73044:D0Z67 RS04450
gene id: 73044:D0Z67_RS04450
uniprot id: A0A4P6TQL7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

73044:D0Z67 RS11820
gene id: 73044:D0Z67_RS11820
uniprot id: A0A4P6TU09
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

73044:D0Z67 RS11880
gene id: 73044:D0Z67_RS11880
uniprot id: A0A4P6TWW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

73044:D0Z67 RS07390
gene id: 73044:D0Z67_RS07390
uniprot id: A0A4P6TTW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

73044:D0Z67 RS14390
gene id: 73044:D0Z67_RS14390
uniprot id: A0A4P6TV50
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS04425
gene id: 73044:D0Z67_RS04425
uniprot id: A0A4P6TQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

73044:D0Z67 RS04280
gene id: 73044:D0Z67_RS04280
uniprot id: A0A4P6TST5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

73044:D0Z67 RS01025
gene id: 73044:D0Z67_RS01025
uniprot id: A0A4P6TUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

73044:D0Z67 RS26395
gene id: 73044:D0Z67_RS26395
uniprot id: A0A4P6U2X9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS26950
gene id: 73044:D0Z67_RS26950
uniprot id: A0A4P6U3D7
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

73044:D0Z67 RS24255
gene id: 73044:D0Z67_RS24255
uniprot id: A0A4P6U019
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

73044:D0Z67 RS22110
gene id: 73044:D0Z67_RS22110
uniprot id: A0A4P6U172
names: Similarity
messages: Belongs to the Nudix hydrolase family.

73044:D0Z67 RS17250
gene id: 73044:D0Z67_RS17250
uniprot id: A0A4P6TZ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

73044:D0Z67 RS11020
gene id: 73044:D0Z67_RS11020
uniprot id: A0A4P6U3Y7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

73044:D0Z67 RS11865
gene id: 73044:D0Z67_RS11865
uniprot id: A0A4P6TZ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

73044:D0Z67 RS19315
gene id: 73044:D0Z67_RS19315
uniprot id: A0A4P6TZD9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

73044:D0Z67 RS19935
gene id: 73044:D0Z67_RS19935
uniprot id: A0A4P6TXN3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS00310
gene id: 73044:D0Z67_RS00310
uniprot id: A0A4P6TQW0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

73044:D0Z67 RS15050
gene id: 73044:D0Z67_RS15050
uniprot id: A0A4P6TY11
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

73044:D0Z67 RS28345
gene id: 73044:D0Z67_RS28345
uniprot id: A0A4P6U155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

73044:D0Z67 RS13175
gene id: 73044:D0Z67_RS13175
uniprot id: A0A4P6TUL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

73044:D0Z67 RS04920
gene id: 73044:D0Z67_RS04920
uniprot id: A0A4P6TSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS10240
gene id: 73044:D0Z67_RS10240
uniprot id: A0A4V0ZZD0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

73044:D0Z67 RS26915
gene id: 73044:D0Z67_RS26915
uniprot id: A0A4P6U2Q5
names: Similarity
messages: Belongs to the TPP enzyme family.

73044:D0Z67 RS28450
gene id: 73044:D0Z67_RS28450
uniprot id: A0A4P6U444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

73044:D0Z67 RS10320
gene id: 73044:D0Z67_RS10320
uniprot id: A0A4P6TYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS11520
gene id: 73044:D0Z67_RS11520
uniprot id: A0A4P6TVT5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS14570
gene id: 73044:D0Z67_RS14570
uniprot id: A0A4P6TX55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

73044:D0Z67 RS16780
gene id: 73044:D0Z67_RS16780
uniprot id: A0A4V0ZZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS09450
gene id: 73044:D0Z67_RS09450
uniprot id: A0A4P6TVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

73044:D0Z67 RS21460
gene id: 73044:D0Z67_RS21460
uniprot id: A0A4P6U0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

73044:D0Z67 RS17715
gene id: 73044:D0Z67_RS17715
uniprot id: A0A4P6TYM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

73044:D0Z67 RS00690
gene id: 73044:D0Z67_RS00690
uniprot id: A0A4P6TU69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS17315
gene id: 73044:D0Z67_RS17315
uniprot id: A0A4P6TYF2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

73044:D0Z67 RS17280
gene id: 73044:D0Z67_RS17280
uniprot id: A0A4P6TW79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

73044:D0Z67 RS13885
gene id: 73044:D0Z67_RS13885
uniprot id: A0A4V0ZZJ2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

73044:D0Z67 RS03615
gene id: 73044:D0Z67_RS03615
uniprot id: A0A4P6TRY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS14325
gene id: 73044:D0Z67_RS14325
uniprot id: A0A4P6TWT2
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

73044:D0Z67 RS21370
gene id: 73044:D0Z67_RS21370
uniprot id: A0A4P6TZX6
names: Similarity
messages: Belongs to the CdaR family.

73044:D0Z67 RS04410
gene id: 73044:D0Z67_RS04410
uniprot id: A0A4P6TVS4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

73044:D0Z67 RS16800
gene id: 73044:D0Z67_RS16800
uniprot id: A0A4P6TWI7
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

73044:D0Z67 RS04270
gene id: 73044:D0Z67_RS04270
uniprot id: A0A4P6TSH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

73044:D0Z67 RS17710
gene id: 73044:D0Z67_RS17710
uniprot id: A0A4P6TYL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

73044:D0Z67 RS07790
gene id: 73044:D0Z67_RS07790
uniprot id: A0A4P6TUH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

73044:D0Z67 RS20235
gene id: 73044:D0Z67_RS20235
uniprot id: A0A4P6U0D1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS27540
gene id: 73044:D0Z67_RS27540
uniprot id: A0A4P6U347
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS07250
gene id: 73044:D0Z67_RS07250
uniprot id: A0A4V0ZZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

73044:D0Z67 RS11870
gene id: 73044:D0Z67_RS11870
uniprot id: A0A4P6TU19
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS21315
gene id: 73044:D0Z67_RS21315
uniprot id: A0A4P6U3A6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS03780
gene id: 73044:D0Z67_RS03780
uniprot id: A0A4P6TSJ5
names: Similarity
messages: Belongs to the UPF0749 family.

73044:D0Z67 RS05680
gene id: 73044:D0Z67_RS05680
uniprot id: A0A4P6TSW6
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

73044:D0Z67 RS16790
gene id: 73044:D0Z67_RS16790
uniprot id: A0A4P6U1B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS24250
gene id: 73044:D0Z67_RS24250
uniprot id: A0A4P6TZR9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06890
gene id: 73044:D0Z67_RS06890
uniprot id: A0A4V0ZZ71
names: Similarity
messages: Belongs to the group II decarboxylase family.

73044:D0Z67 RS20230
gene id: 73044:D0Z67_RS20230
uniprot id: A0A4P6TZQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

73044:D0Z67 RS00795
gene id: 73044:D0Z67_RS00795
uniprot id: A0A4P6TU83
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS29345
gene id: 73044:D0Z67_RS29345
uniprot id: A0A4P6U822
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS28235
gene id: 73044:D0Z67_RS28235
uniprot id: A0A4P6U385
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS28390
gene id: 73044:D0Z67_RS28390
uniprot id: A0A4P6U431
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

73044:D0Z67 RS12515
gene id: 73044:D0Z67_RS12515
uniprot id: A0A4P6TW13
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

73044:D0Z67 RS16115
gene id: 73044:D0Z67_RS16115
uniprot id: A0A4P6TXU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

73044:D0Z67 RS17170
gene id: 73044:D0Z67_RS17170
uniprot id: A0A4P6TW57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

73044:D0Z67 RS18845
gene id: 73044:D0Z67_RS18845
uniprot id: A0A4P6TYT9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

73044:D0Z67 RS20605
gene id: 73044:D0Z67_RS20605
uniprot id: A0A4P6TXX9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

73044:D0Z67 RS08950
gene id: 73044:D0Z67_RS08950
uniprot id: A0A4P6TXS7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

73044:D0Z67 RS12415
gene id: 73044:D0Z67_RS12415
uniprot id: A0A4P6TVZ0
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

73044:D0Z67 RS10975
gene id: 73044:D0Z67_RS10975
uniprot id: A0A4P6TTL3
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

73044:D0Z67 RS03755
gene id: 73044:D0Z67_RS03755
uniprot id: A0A4P6TQC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

73044:D0Z67 RS19455
gene id: 73044:D0Z67_RS19455
uniprot id: A0A4P6TXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS00620
gene id: 73044:D0Z67_RS00620
uniprot id: A0A4V0ZYW2
names: Similarity
messages: Belongs to the universal stress protein A family.

73044:D0Z67 RS13950
gene id: 73044:D0Z67_RS13950
uniprot id: A0A4P6TXG7
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

73044:D0Z67 RS03925
gene id: 73044:D0Z67_RS03925
uniprot id: A0A4P6TS35
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS05205
gene id: 73044:D0Z67_RS05205
uniprot id: A0A4P6TSP0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS16170
gene id: 73044:D0Z67_RS16170
uniprot id: A0A4P6TXW0
names: Subcellular Location Annotation
messages: Mitochondrion

73044:D0Z67 RS14245
gene id: 73044:D0Z67_RS14245
uniprot id: A0A4P6TWZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

73044:D0Z67 RS11775
gene id: 73044:D0Z67_RS11775
uniprot id: A0A4P6TUB1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

73044:D0Z67 RS10915
gene id: 73044:D0Z67_RS10915
uniprot id: A0A4P6TVA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

73044:D0Z67 RS04225
gene id: 73044:D0Z67_RS04225
uniprot id: A0A4P6TSS6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

73044:D0Z67 RS09965
gene id: 73044:D0Z67_RS09965
uniprot id: A0A4P6TVH9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06740
gene id: 73044:D0Z67_RS06740
uniprot id: A0A4P6TRQ9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

73044:D0Z67 RS13700
gene id: 73044:D0Z67_RS13700
uniprot id: A0A4P6TZU4
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

73044:D0Z67 RS19945
gene id: 73044:D0Z67_RS19945
uniprot id: A0A4P6U082
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

73044:D0Z67 RS10835
gene id: 73044:D0Z67_RS10835
uniprot id: A0A4P6TVH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS00265
gene id: 73044:D0Z67_RS00265
uniprot id: A0A4P6TNU3
names: Subunit
messages: Homodimer.

73044:D0Z67 RS27520
gene id: 73044:D0Z67_RS27520
uniprot id: A0A4P6U615
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

73044:D0Z67 RS27840
gene id: 73044:D0Z67_RS27840
uniprot id: A0A4P6U0R9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

73044:D0Z67 RS17640
gene id: 73044:D0Z67_RS17640
uniprot id: A0A4P6U2G9
names: Similarity
messages: Belongs to the peptidase C40 family.

73044:D0Z67 RS15415
gene id: 73044:D0Z67_RS15415
uniprot id: A0A4P6TVV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS03335
gene id: 73044:D0Z67_RS03335
uniprot id: A0A4P6TQ61
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

73044:D0Z67 RS22710
gene id: 73044:D0Z67_RS22710
uniprot id: A0A4P6U0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

73044:D0Z67 RS11380
gene id: 73044:D0Z67_RS11380
uniprot id: A0A4P6TYV3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

73044:D0Z67 RS18965
gene id: 73044:D0Z67_RS18965
uniprot id: A0A4P6TX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS22450
gene id: 73044:D0Z67_RS22450
uniprot id: A0A4P6U0P9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS18590
gene id: 73044:D0Z67_RS18590
uniprot id: A0A4P6TZL0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08925
gene id: 73044:D0Z67_RS08925
uniprot id: A0A4P6TUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS10930
gene id: 73044:D0Z67_RS10930
uniprot id: A0A4P6TTW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

73044:D0Z67 RS25460
gene id: 73044:D0Z67_RS25460
uniprot id: A0A4P6U098
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

73044:D0Z67 RS18940
gene id: 73044:D0Z67_RS18940
uniprot id: A0A4P6TZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS08610
gene id: 73044:D0Z67_RS08610
uniprot id: A0A4P6TVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

73044:D0Z67 RS17020
gene id: 73044:D0Z67_RS17020
uniprot id: A0A4P6TZ03
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS12650
gene id: 73044:D0Z67_RS12650
uniprot id: A0A4P6TUD6
names: Similarity
messages: Belongs to the FemABX family.

73044:D0Z67 RS23400
gene id: 73044:D0Z67_RS23400
uniprot id: A0A4P6U1M7
names: Similarity
messages: Belongs to the TPP enzyme family.

73044:D0Z67 RS11770
gene id: 73044:D0Z67_RS11770
uniprot id: A0A4P6TTZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

73044:D0Z67 RS05350
gene id: 73044:D0Z67_RS05350
uniprot id: A0A4P6TR40
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS24750
gene id: 73044:D0Z67_RS24750
uniprot id: A0A4P6TZZ5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06840
gene id: 73044:D0Z67_RS06840
uniprot id: A0A4P6TTE8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS10715
gene id: 73044:D0Z67_RS10715
uniprot id: A0A4P6U755
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

73044:D0Z67 RS01380
gene id: 73044:D0Z67_RS01380
uniprot id: A0A4P6TPA3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS00050
gene id: 73044:D0Z67_RS00050
uniprot id: A0A4P6TQV5
names: Similarity
messages: Belongs to the peptidase M13 family.

73044:D0Z67 RS06550
gene id: 73044:D0Z67_RS06550
uniprot id: A0A4P6TTX6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

73044:D0Z67 RS16255
gene id: 73044:D0Z67_RS16255
uniprot id: A0A4P6U132
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS29540
gene id: 73044:D0Z67_RS29540
uniprot id: A0A4P6U594
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS00055
gene id: 73044:D0Z67_RS00055
uniprot id: A0A4P6TNP9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06160
gene id: 73044:D0Z67_RS06160
uniprot id: A0A4P6TUG3
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS10790
gene id: 73044:D0Z67_RS10790
uniprot id: A0A4P6TTI0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS17295
gene id: 73044:D0Z67_RS17295
uniprot id: A0A4P6U1J2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

73044:D0Z67 RS04375
gene id: 73044:D0Z67_RS04375
uniprot id: A0A4P6TTN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

73044:D0Z67 RS27765
gene id: 73044:D0Z67_RS27765
uniprot id: A0A4P6U301
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

73044:D0Z67 RS14080
gene id: 73044:D0Z67_RS14080
uniprot id: A0A4P6TWP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

73044:D0Z67 RS10900
gene id: 73044:D0Z67_RS10900
uniprot id: A0A4P6TVY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

73044:D0Z67 RS02535
gene id: 73044:D0Z67_RS02535
uniprot id: A0A4P6TPT5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04215
gene id: 73044:D0Z67_RS04215
uniprot id: A0A4P6TSG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

73044:D0Z67 RS28655
gene id: 73044:D0Z67_RS28655
uniprot id: A0A4V1A099
names: Similarity
messages: Belongs to the HupF/HypC family.

73044:D0Z67 RS08910
gene id: 73044:D0Z67_RS08910
uniprot id: A0A4P6TSZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS08035
gene id: 73044:D0Z67_RS08035
uniprot id: A0A4V0ZZ91
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

73044:D0Z67 RS09535
gene id: 73044:D0Z67_RS09535
uniprot id: A0A4P6TSY9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

73044:D0Z67 RS22755
gene id: 73044:D0Z67_RS22755
uniprot id: A0A4P6TYN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

73044:D0Z67 RS18500
gene id: 73044:D0Z67_RS18500
uniprot id: A0A4P6TYN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS20225
gene id: 73044:D0Z67_RS20225
uniprot id: A0A4P6TZS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

73044:D0Z67 RS04240
gene id: 73044:D0Z67_RS04240
uniprot id: A0A4P6TS87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

73044:D0Z67 RS20115
gene id: 73044:D0Z67_RS20115
uniprot id: A0A4P6TZN9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

73044:D0Z67 RS09660
gene id: 73044:D0Z67_RS09660
uniprot id: A0A4P6TVD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

73044:D0Z67 RS13530
gene id: 73044:D0Z67_RS13530
uniprot id: A0A4P6TV30
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

73044:D0Z67 RS02845
gene id: 73044:D0Z67_RS02845
uniprot id: A0A4P6TPX6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

73044:D0Z67 RS14560
gene id: 73044:D0Z67_RS14560
uniprot id: A0A4P6TXY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

73044:D0Z67 RS01330
gene id: 73044:D0Z67_RS01330
uniprot id: A0A4V0ZYX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS11180
gene id: 73044:D0Z67_RS11180
uniprot id: A0A4P6TTP8
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS24320
gene id: 73044:D0Z67_RS24320
uniprot id: A0A4P6U230
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

73044:D0Z67 RS17230
gene id: 73044:D0Z67_RS17230
uniprot id: A0A4P6TY35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

73044:D0Z67 RS28815
gene id: 73044:D0Z67_RS28815
uniprot id: A0A4P6U1C2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS05775
gene id: 73044:D0Z67_RS05775
uniprot id: A0A4V0ZZ51
names: Similarity
messages: Belongs to the TlyA family.

73044:D0Z67 RS07600
gene id: 73044:D0Z67_RS07600
uniprot id: A0A4P6TSE0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

73044:D0Z67 RS17445
gene id: 73044:D0Z67_RS17445
uniprot id: A0A4V0ZZQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

73044:D0Z67 RS12920
gene id: 73044:D0Z67_RS12920
uniprot id: A0A4P6TWV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

73044:D0Z67 RS05050
gene id: 73044:D0Z67_RS05050
uniprot id: A0A4P6TR99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

73044:D0Z67 RS16655
gene id: 73044:D0Z67_RS16655
uniprot id: A0A4P6TYT6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS23160
gene id: 73044:D0Z67_RS23160
uniprot id: A0A4P6U0Q7
names: Similarity
messages: Belongs to the terpene synthase family.

73044:D0Z67 RS04390
gene id: 73044:D0Z67_RS04390
uniprot id: A0A4P6TSV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS13995
gene id: 73044:D0Z67_RS13995
uniprot id: A0A4P6TWW4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

73044:D0Z67 RS06815
gene id: 73044:D0Z67_RS06815
uniprot id: A0A4P6TTN5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

73044:D0Z67 RS18900
gene id: 73044:D0Z67_RS18900
uniprot id: A0A4V0ZZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS11575
gene id: 73044:D0Z67_RS11575
uniprot id: A0A4P6TVU3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

73044:D0Z67 RS22015
gene id: 73044:D0Z67_RS22015
uniprot id: A0A4P6TYC3
names: Similarity
messages: Belongs to the IucA/IucC family.

73044:D0Z67 RS19510
gene id: 73044:D0Z67_RS19510
uniprot id: A0A4P6U007
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

73044:D0Z67 RS14700
gene id: 73044:D0Z67_RS14700
uniprot id: A0A4P6TXU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

73044:D0Z67 RS07230
gene id: 73044:D0Z67_RS07230
uniprot id: A0A4P6TTU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS28355
gene id: 73044:D0Z67_RS28355
uniprot id: A0A4P6U3D6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

73044:D0Z67 RS19060
gene id: 73044:D0Z67_RS19060
uniprot id: A0A4V0ZZT3
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

73044:D0Z67 RS11350
gene id: 73044:D0Z67_RS11350
uniprot id: A0A4P6TVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

73044:D0Z67 RS10275
gene id: 73044:D0Z67_RS10275
uniprot id: A0A4P6TW71
names: Similarity
messages: Belongs to the universal stress protein A family.

73044:D0Z67 RS22170
gene id: 73044:D0Z67_RS22170
uniprot id: A0A4P6U0K5
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS16560
gene id: 73044:D0Z67_RS16560
uniprot id: A0A4P6TWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

73044:D0Z67 RS12935
gene id: 73044:D0Z67_RS12935
uniprot id: A0A4P6TW80
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

73044:D0Z67 RS11785
gene id: 73044:D0Z67_RS11785
uniprot id: A0A4P6TVZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

73044:D0Z67 RS03370
gene id: 73044:D0Z67_RS03370
uniprot id: A0A4P6TQ55
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS28125
gene id: 73044:D0Z67_RS28125
uniprot id: A0A4P6U116
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS16985
gene id: 73044:D0Z67_RS16985
uniprot id: A0A4P6TYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

73044:D0Z67 RS04065
gene id: 73044:D0Z67_RS04065
uniprot id: A0A4P6TSF9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS25015
gene id: 73044:D0Z67_RS25015
uniprot id: A0A4P6TZL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS16675
gene id: 73044:D0Z67_RS16675
uniprot id: A0A4P6TVX7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS17765
gene id: 73044:D0Z67_RS17765
uniprot id: A0A4P6TYM1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

73044:D0Z67 RS17405
gene id: 73044:D0Z67_RS17405
uniprot id: A0A4P6TWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

73044:D0Z67 RS18400
gene id: 73044:D0Z67_RS18400
uniprot id: A0A4P6U222
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

73044:D0Z67 RS14440
gene id: 73044:D0Z67_RS14440
uniprot id: A0A4P6U232
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS20160
gene id: 73044:D0Z67_RS20160
uniprot id: A0A4P6TZS0
names: Similarity
messages: Belongs to the UPF0045 family.

73044:D0Z67 RS04300
gene id: 73044:D0Z67_RS04300
uniprot id: A0A4P6TS96
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

73044:D0Z67 RS04315
gene id: 73044:D0Z67_RS04315
uniprot id: A0A4P6TQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

73044:D0Z67 RS02000
gene id: 73044:D0Z67_RS02000
uniprot id: A0A4P6TPK4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS24620
gene id: 73044:D0Z67_RS24620
uniprot id: A0A4P6U1B0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

73044:D0Z67 RS15215
gene id: 73044:D0Z67_RS15215
uniprot id: A0A4P6TY44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

73044:D0Z67 RS09680
gene id: 73044:D0Z67_RS09680
uniprot id: A0A4P6TUQ8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

73044:D0Z67 RS18265
gene id: 73044:D0Z67_RS18265
uniprot id: A0A4P6TZG3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

73044:D0Z67 RS06610
gene id: 73044:D0Z67_RS06610
uniprot id: A0A4V0ZZ66
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS11750
gene id: 73044:D0Z67_RS11750
uniprot id: A0A4P6TTW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

73044:D0Z67 RS25835
gene id: 73044:D0Z67_RS25835
uniprot id: A0A4P6U246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

73044:D0Z67 RS20895
gene id: 73044:D0Z67_RS20895
uniprot id: A0A4P6U018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

73044:D0Z67 RS03425
gene id: 73044:D0Z67_RS03425
uniprot id: A0A4P6TQ65
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS04660
gene id: 73044:D0Z67_RS04660
uniprot id: A0A4P6TQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

73044:D0Z67 RS10235
gene id: 73044:D0Z67_RS10235
uniprot id: A0A4P6TTA5
names: Similarity
messages: Belongs to the group II decarboxylase family.

73044:D0Z67 RS17210
gene id: 73044:D0Z67_RS17210
uniprot id: A0A4P6TYD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

73044:D0Z67 RS12370
gene id: 73044:D0Z67_RS12370
uniprot id: A0A4P6TX30
names: Similarity
messages: Belongs to the peptidase S11 family.

73044:D0Z67 RS10155
gene id: 73044:D0Z67_RS10155
uniprot id: A0A4P6TW55
names: Similarity
messages: Belongs to the TPP enzyme family.

73044:D0Z67 RS03415
gene id: 73044:D0Z67_RS03415
uniprot id: A0A4P6TS59
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

73044:D0Z67 RS23650
gene id: 73044:D0Z67_RS23650
uniprot id: A0A4P6TZS4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

73044:D0Z67 RS25300
gene id: 73044:D0Z67_RS25300
uniprot id: A0A4P6U2N0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

73044:D0Z67 RS11280
gene id: 73044:D0Z67_RS11280
uniprot id: A0A4P6TYT7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

73044:D0Z67 RS16085
gene id: 73044:D0Z67_RS16085
uniprot id: A0A4P6TXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

73044:D0Z67 RS10995
gene id: 73044:D0Z67_RS10995
uniprot id: A0A4P6TVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

73044:D0Z67 RS24945
gene id: 73044:D0Z67_RS24945
uniprot id: A0A4P6U1Q4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

73044:D0Z67 RS26985
gene id: 73044:D0Z67_RS26985
uniprot id: A0A4P6U178
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

73044:D0Z67 RS22835
gene id: 73044:D0Z67_RS22835
uniprot id: A0A4P6U0L3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

73044:D0Z67 RS03800
gene id: 73044:D0Z67_RS03800
uniprot id: A0A4P6TVH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

73044:D0Z67 RS12110
gene id: 73044:D0Z67_RS12110
uniprot id: A0A4P6TW43
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04110
gene id: 73044:D0Z67_RS04110
uniprot id: A0A4P6TTJ0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

73044:D0Z67 RS25310
gene id: 73044:D0Z67_RS25310
uniprot id: A0A4V1A042
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS14540
gene id: 73044:D0Z67_RS14540
uniprot id: A0A4P6TWW8
names: Similarity
messages: Belongs to the thioredoxin family.

73044:D0Z67 RS03520
gene id: 73044:D0Z67_RS03520
uniprot id: A0A4P6TQ90
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

73044:D0Z67 RS04050
gene id: 73044:D0Z67_RS04050
uniprot id: A0A4P6TQQ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS16135
gene id: 73044:D0Z67_RS16135
uniprot id: A0A4P6TXL7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

73044:D0Z67 RS06650
gene id: 73044:D0Z67_RS06650
uniprot id: A0A4P6U3S2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

73044:D0Z67 RS03155
gene id: 73044:D0Z67_RS03155
uniprot id: A0A4P6TV84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

73044:D0Z67 RS20060
gene id: 73044:D0Z67_RS20060
uniprot id: A0A4P6TZQ3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

73044:D0Z67 RS18915
gene id: 73044:D0Z67_RS18915
uniprot id: A0A4P6TX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS26635
gene id: 73044:D0Z67_RS26635
uniprot id: A0A4P6U2Q2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

73044:D0Z67 RS20015
gene id: 73044:D0Z67_RS20015
uniprot id: A0A4P6TZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

73044:D0Z67 RS20170
gene id: 73044:D0Z67_RS20170
uniprot id: A0A4P6TZQ0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS10325
gene id: 73044:D0Z67_RS10325
uniprot id: A0A4P6TTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS16510
gene id: 73044:D0Z67_RS16510
uniprot id: A0A4P6TWD6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

73044:D0Z67 RS07625
gene id: 73044:D0Z67_RS07625
uniprot id: A0A4P6TUF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

73044:D0Z67 RS15880
gene id: 73044:D0Z67_RS15880
uniprot id: A0A4P6TXS1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS06880
gene id: 73044:D0Z67_RS06880
uniprot id: A0A4P6TU33
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

73044:D0Z67 RS05875
gene id: 73044:D0Z67_RS05875
uniprot id: A0A4P6TRC4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS15055
gene id: 73044:D0Z67_RS15055
uniprot id: A0A4P6TV73
names: Similarity
messages: Belongs to the LOR family.

73044:D0Z67 RS16725
gene id: 73044:D0Z67_RS16725
uniprot id: A0A4P6TVY6
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS08140
gene id: 73044:D0Z67_RS08140
uniprot id: A0A4V0ZZ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

73044:D0Z67 RS13335
gene id: 73044:D0Z67_RS13335
uniprot id: A0A4P6TWM0
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

73044:D0Z67 RS26850
gene id: 73044:D0Z67_RS26850
uniprot id: A0A4P6U5R6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS28810
gene id: 73044:D0Z67_RS28810
uniprot id: A0A4P6U4A1
names: Similarity
messages: Belongs to the CFA/CMAS family.

73044:D0Z67 RS11635
gene id: 73044:D0Z67_RS11635
uniprot id: A0A4P6TW90
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS27670
gene id: 73044:D0Z67_RS27670
uniprot id: A0A4P6U0P5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

73044:D0Z67 RS05140
gene id: 73044:D0Z67_RS05140
uniprot id: A0A4P6TQW6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

73044:D0Z67 RS22265
gene id: 73044:D0Z67_RS22265
uniprot id: A0A4P6TYP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS05765
gene id: 73044:D0Z67_RS05765
uniprot id: A0A4P6TTK0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

73044:D0Z67 RS11730
gene id: 73044:D0Z67_RS11730
uniprot id: A0A4P6TWT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

73044:D0Z67 RS09335
gene id: 73044:D0Z67_RS09335
uniprot id: A0A4P6TV83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

73044:D0Z67 RS28460
gene id: 73044:D0Z67_RS28460
uniprot id: A0A4V1A096
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

73044:D0Z67 RS07000
gene id: 73044:D0Z67_RS07000
uniprot id: A0A4P6TTQ6
names: Similarity
messages: Belongs to the TrpC family.

73044:D0Z67 RS14310
gene id: 73044:D0Z67_RS14310
uniprot id: A0A4P6TXM5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS00760
gene id: 73044:D0Z67_RS00760
uniprot id: A0A4P6TPC5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS21435
gene id: 73044:D0Z67_RS21435
uniprot id: A0A4P6TYA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS01275
gene id: 73044:D0Z67_RS01275
uniprot id: A0A4V0ZYX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS22380
gene id: 73044:D0Z67_RS22380
uniprot id: A0A4P6TZ29
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09580
gene id: 73044:D0Z67_RS09580
uniprot id: A0A4P6TY33
names: Similarity
messages: Belongs to the peptidase S8 family.

73044:D0Z67 RS09530
gene id: 73044:D0Z67_RS09530
uniprot id: A0A4P6TY25
names: Similarity
messages: Belongs to the FPG family.

73044:D0Z67 RS10685
gene id: 73044:D0Z67_RS10685
uniprot id: A0A4V0ZZD7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

73044:D0Z67 RS11560
gene id: 73044:D0Z67_RS11560
uniprot id: A0A4P6TU73
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

73044:D0Z67 RS18410
gene id: 73044:D0Z67_RS18410
uniprot id: A0A4P6TX88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS08195
gene id: 73044:D0Z67_RS08195
uniprot id: A0A4P6TSD3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

73044:D0Z67 RS24345
gene id: 73044:D0Z67_RS24345
uniprot id: A0A4V1A025
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

73044:D0Z67 RS03160
gene id: 73044:D0Z67_RS03160
uniprot id: A0A4P6TQ31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS26870
gene id: 73044:D0Z67_RS26870
uniprot id: A0A4P6U161
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS22385
gene id: 73044:D0Z67_RS22385
uniprot id: A0A4P6U185
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

73044:D0Z67 RS04340
gene id: 73044:D0Z67_RS04340
uniprot id: A0A4P6TQJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

73044:D0Z67 RS20470
gene id: 73044:D0Z67_RS20470
uniprot id: A0A4V0ZZV8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

73044:D0Z67 RS06145
gene id: 73044:D0Z67_RS06145
uniprot id: A0A4P6TWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

73044:D0Z67 RS17505
gene id: 73044:D0Z67_RS17505
uniprot id: A0A4P6TY78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS17215
gene id: 73044:D0Z67_RS17215
uniprot id: A0A4P6TYY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

73044:D0Z67 RS17630
gene id: 73044:D0Z67_RS17630
uniprot id: A0A4P6U7E3
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08090
gene id: 73044:D0Z67_RS08090
uniprot id: A0A4V0ZZ92
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

73044:D0Z67 RS17600
gene id: 73044:D0Z67_RS17600
uniprot id: A0A4P6TZ50
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

73044:D0Z67 RS26510
gene id: 73044:D0Z67_RS26510
uniprot id: A0A4P6U2Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

73044:D0Z67 RS11850
gene id: 73044:D0Z67_RS11850
uniprot id: A0A4P6TTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

73044:D0Z67 RS21985
gene id: 73044:D0Z67_RS21985
uniprot id: A0A4P6U121
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS22180
gene id: 73044:D0Z67_RS22180
uniprot id: A0A4P6U4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS28210
gene id: 73044:D0Z67_RS28210
uniprot id: A0A4P6U1R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS09585
gene id: 73044:D0Z67_RS09585
uniprot id: A0A4P6TSZ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS04135
gene id: 73044:D0Z67_RS04135
uniprot id: A0A4V0ZZ22
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS06985
gene id: 73044:D0Z67_RS06985
uniprot id: A0A4P6TS36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

73044:D0Z67 RS15460
gene id: 73044:D0Z67_RS15460
uniprot id: A0A4P6U0N7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS07025
gene id: 73044:D0Z67_RS07025
uniprot id: A0A4P6U4D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS06210
gene id: 73044:D0Z67_RS06210
uniprot id: A0A4P6TRH5
names: Similarity
messages: Belongs to the CobH/CbiC family.

73044:D0Z67 RS23260
gene id: 73044:D0Z67_RS23260
uniprot id: A0A4P6TYV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS26185
gene id: 73044:D0Z67_RS26185
uniprot id: A0A4P6U2A1
names: Similarity
messages: Belongs to the CapA family.

73044:D0Z67 RS03110
gene id: 73044:D0Z67_RS03110
uniprot id: A0A4P6TQ21
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS06485
gene id: 73044:D0Z67_RS06485
uniprot id: A0A4P6TUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

73044:D0Z67 RS02370
gene id: 73044:D0Z67_RS02370
uniprot id: A0A4P6TPR0
names: Subcellular Location Annotation
messages: Cell membrane

73044:D0Z67 RS06220
gene id: 73044:D0Z67_RS06220
uniprot id: A0A4P6TUH2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS15115
gene id: 73044:D0Z67_RS15115
uniprot id: A0A4P6TX66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS14620
gene id: 73044:D0Z67_RS14620
uniprot id: A0A4P6TXZ7
names: Similarity
messages: Belongs to the UPF0232 family.

73044:D0Z67 RS08135
gene id: 73044:D0Z67_RS08135
uniprot id: A0A4P6TSC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

73044:D0Z67 RS25740
gene id: 73044:D0Z67_RS25740
uniprot id: A0A4P6TZW4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

73044:D0Z67 RS19445
gene id: 73044:D0Z67_RS19445
uniprot id: A0A4P6TZF0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

73044:D0Z67 RS11185
gene id: 73044:D0Z67_RS11185
uniprot id: A0A4P6TU06
names: Similarity
messages: Belongs to the PGI/PMI family.

73044:D0Z67 RS14970
gene id: 73044:D0Z67_RS14970
uniprot id: A0A4P6TY46
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

73044:D0Z67 RS01870
gene id: 73044:D0Z67_RS01870
uniprot id: A0A4P6TRP6
names: Similarity
messages: Belongs to the Dps family.

73044:D0Z67 RS06490
gene id: 73044:D0Z67_RS06490
uniprot id: A0A4P6TTH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS05625
gene id: 73044:D0Z67_RS05625
uniprot id: A0A4V0ZZ48
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS23520
gene id: 73044:D0Z67_RS23520
uniprot id: A0A4P6U1D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

73044:D0Z67 RS17000
gene id: 73044:D0Z67_RS17000
uniprot id: A0A4P6TXZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS12005
gene id: 73044:D0Z67_RS12005
uniprot id: A0A4P6U1Z2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

73044:D0Z67 RS20885
gene id: 73044:D0Z67_RS20885
uniprot id: A0A4P6U021
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

73044:D0Z67 RS22980
gene id: 73044:D0Z67_RS22980
uniprot id: A0A4P6U1L2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS19345
gene id: 73044:D0Z67_RS19345
uniprot id: A0A4P6U2G6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

73044:D0Z67 RS08885
gene id: 73044:D0Z67_RS08885
uniprot id: A0A4P6TUC0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS14525
gene id: 73044:D0Z67_RS14525
uniprot id: A0A4P6TXR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS13495
gene id: 73044:D0Z67_RS13495
uniprot id: A0A4P6TWP2
names: Similarity
messages: Belongs to the CsoR family.

73044:D0Z67 RS11170
gene id: 73044:D0Z67_RS11170
uniprot id: A0A4P6TVE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

73044:D0Z67 RS28350
gene id: 73044:D0Z67_RS28350
uniprot id: A0A4V1A094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

73044:D0Z67 RS00440
gene id: 73044:D0Z67_RS00440
uniprot id: A0A4P6U6Q6
names: Similarity
messages: Belongs to the peptidase M4 family.

73044:D0Z67 RS19995
gene id: 73044:D0Z67_RS19995
uniprot id: A0A4P6TXP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

73044:D0Z67 RS06340
gene id: 73044:D0Z67_RS06340
uniprot id: A0A4P6TTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS03795
gene id: 73044:D0Z67_RS03795
uniprot id: A0A4P6TS17
names: Similarity
messages: Belongs to the phosphohexose mutase family.

73044:D0Z67 RS22660
gene id: 73044:D0Z67_RS22660
uniprot id: A0A4P6U0I5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS25235
gene id: 73044:D0Z67_RS25235
uniprot id: A0A4P6U2G5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

73044:D0Z67 RS04420
gene id: 73044:D0Z67_RS04420
uniprot id: A0A4P6TQM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS04755
gene id: 73044:D0Z67_RS04755
uniprot id: A0A4P6TQQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

73044:D0Z67 RS20055
gene id: 73044:D0Z67_RS20055
uniprot id: A0A4P6U0A0
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

73044:D0Z67 RS27605
gene id: 73044:D0Z67_RS27605
uniprot id: A0A4P6U3P5
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

73044:D0Z67 RS20330
gene id: 73044:D0Z67_RS20330
uniprot id: A0A4P6TY30
names: Similarity
messages: Belongs to the thioredoxin family.

73044:D0Z67 RS16995
gene id: 73044:D0Z67_RS16995
uniprot id: A0A4V0ZZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS13800
gene id: 73044:D0Z67_RS13800
uniprot id: A0A4P6TWT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS22290
gene id: 73044:D0Z67_RS22290
uniprot id: A0A4P6U0M3
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

73044:D0Z67 RS26155
gene id: 73044:D0Z67_RS26155
uniprot id: A0A4P6U256
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

73044:D0Z67 RS21400
gene id: 73044:D0Z67_RS21400
uniprot id: A0A4P6U095
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

73044:D0Z67 RS25370
gene id: 73044:D0Z67_RS25370
uniprot id: A0A4V1A043
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS18970
gene id: 73044:D0Z67_RS18970
uniprot id: A0A4P6TXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS08210
gene id: 73044:D0Z67_RS08210
uniprot id: A0A4P6TXF4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

73044:D0Z67 RS05910
gene id: 73044:D0Z67_RS05910
uniprot id: A0A4V0ZZ53
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

73044:D0Z67 RS26190
gene id: 73044:D0Z67_RS26190
uniprot id: A0A4P6U310
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07960
gene id: 73044:D0Z67_RS07960
uniprot id: A0A4P6TU59
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

73044:D0Z67 RS11260
gene id: 73044:D0Z67_RS11260
uniprot id: A0A4P6TW38
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

73044:D0Z67 RS07195
gene id: 73044:D0Z67_RS07195
uniprot id: A0A4V0ZZ76
names: Similarity
messages: Belongs to the YggT family.

73044:D0Z67 RS24940
gene id: 73044:D0Z67_RS24940
uniprot id: A0A4P6U202
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

73044:D0Z67 RS03015
gene id: 73044:D0Z67_RS03015
uniprot id: A0A4P6TRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

73044:D0Z67 RS23670
gene id: 73044:D0Z67_RS23670
uniprot id: A0A4P6U1X8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS05345
gene id: 73044:D0Z67_RS05345
uniprot id: A0A4P6TW81
names: Similarity
messages: Belongs to the Nudix hydrolase family.

73044:D0Z67 RS09050
gene id: 73044:D0Z67_RS09050
uniprot id: A0A4P6TV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS28865
gene id: 73044:D0Z67_RS28865
uniprot id: A0A4P6U1C9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS16700
gene id: 73044:D0Z67_RS16700
uniprot id: A0A4P6TWH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

73044:D0Z67 RS22610
gene id: 73044:D0Z67_RS22610
uniprot id: A0A4P6TZ73
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03745
gene id: 73044:D0Z67_RS03745
uniprot id: A0A4P6TS04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

73044:D0Z67 RS20095
gene id: 73044:D0Z67_RS20095
uniprot id: A0A4P6TXQ6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07335
gene id: 73044:D0Z67_RS07335
uniprot id: A0A4P6TTV5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

73044:D0Z67 RS21485
gene id: 73044:D0Z67_RS21485
uniprot id: A0A4P6U3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

73044:D0Z67 RS11320
gene id: 73044:D0Z67_RS11320
uniprot id: A0A4V0ZZE8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

73044:D0Z67 RS18370
gene id: 73044:D0Z67_RS18370
uniprot id: A0A4P6TZI1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

73044:D0Z67 RS27480
gene id: 73044:D0Z67_RS27480
uniprot id: A0A4P6U335
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

73044:D0Z67 RS07055
gene id: 73044:D0Z67_RS07055
uniprot id: A0A4P6TUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

73044:D0Z67 RS04210
gene id: 73044:D0Z67_RS04210
uniprot id: A0A4P6TTK8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

73044:D0Z67 RS15605
gene id: 73044:D0Z67_RS15605
uniprot id: A0A4P6TXL8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

73044:D0Z67 RS19930
gene id: 73044:D0Z67_RS19930
uniprot id: A0A4P6U2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

73044:D0Z67 RS17815
gene id: 73044:D0Z67_RS17815
uniprot id: A0A4P6TYM9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS01145
gene id: 73044:D0Z67_RS01145
uniprot id: A0A4V0ZYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

73044:D0Z67 RS12240
gene id: 73044:D0Z67_RS12240
uniprot id: A0A4P6TUI4
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

73044:D0Z67 RS21110
gene id: 73044:D0Z67_RS21110
uniprot id: A0A4P6U0R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

73044:D0Z67 RS06270
gene id: 73044:D0Z67_RS06270
uniprot id: A0A4P6TUI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

73044:D0Z67 RS07950
gene id: 73044:D0Z67_RS07950
uniprot id: A0A4P6TV85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS06190
gene id: 73044:D0Z67_RS06190
uniprot id: A0A4P6TRC0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS00340
gene id: 73044:D0Z67_RS00340
uniprot id: A0A4P6TNV6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS25785
gene id: 73044:D0Z67_RS25785
uniprot id: A0A4P6U234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

73044:D0Z67 RS07175
gene id: 73044:D0Z67_RS07175
uniprot id: A0A4P6TTT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

73044:D0Z67 RS21520
gene id: 73044:D0Z67_RS21520
uniprot id: A0A4P6TY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

73044:D0Z67 RS25245
gene id: 73044:D0Z67_RS25245
uniprot id: A0A4P6U1U7
names: Similarity
messages: Belongs to the universal stress protein A family.

73044:D0Z67 RS04950
gene id: 73044:D0Z67_RS04950
uniprot id: A0A4P6TTX8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS22400
gene id: 73044:D0Z67_RS22400
uniprot id: A0A4P6U1C3
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS09290
gene id: 73044:D0Z67_RS09290
uniprot id: A0A4V0ZZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

73044:D0Z67 RS07120
gene id: 73044:D0Z67_RS07120
uniprot id: A0A4P6TTS4
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS03330
gene id: 73044:D0Z67_RS03330
uniprot id: A0A4P6TVA8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

73044:D0Z67 RS19950
gene id: 73044:D0Z67_RS19950
uniprot id: A0A4P6TZN5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

73044:D0Z67 RS26910
gene id: 73044:D0Z67_RS26910
uniprot id: A0A4V1A069
names: Similarity
messages: Belongs to the glutamate synthase family.

73044:D0Z67 RS28730
gene id: 73044:D0Z67_RS28730
uniprot id: A0A4P6U1Y7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

73044:D0Z67 RS06500
gene id: 73044:D0Z67_RS06500
uniprot id: A0A4P6TTW8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

73044:D0Z67 RS19465
gene id: 73044:D0Z67_RS19465
uniprot id: A0A4P6TZ43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

73044:D0Z67 RS12365
gene id: 73044:D0Z67_RS12365
uniprot id: A0A4P6TUK4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS20180
gene id: 73044:D0Z67_RS20180
uniprot id: A0A4P6TXL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS03395
gene id: 73044:D0Z67_RS03395
uniprot id: A0A4P6TQ71
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

73044:D0Z67 RS17425
gene id: 73044:D0Z67_RS17425
uniprot id: A0A4P6TZ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

73044:D0Z67 RS17195
gene id: 73044:D0Z67_RS17195
uniprot id: A0A4P6TWP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

73044:D0Z67 RS11525
gene id: 73044:D0Z67_RS11525
uniprot id: A0A4P6TW74
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS15025
gene id: 73044:D0Z67_RS15025
uniprot id: A0A4P6TVP6
names: Similarity
messages: Belongs to the peptidase S11 family.

73044:D0Z67 RS21900
gene id: 73044:D0Z67_RS21900
uniprot id: A0A4V0ZZY2
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

73044:D0Z67 RS11640
gene id: 73044:D0Z67_RS11640
uniprot id: A0A4P6TTU7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS02490
gene id: 73044:D0Z67_RS02490
uniprot id: A0A4P6TQ29
names: Similarity
messages: Belongs to the UPF0047 family.

73044:D0Z67 RS23115
gene id: 73044:D0Z67_RS23115
uniprot id: A0A4P6U443
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

73044:D0Z67 RS04100
gene id: 73044:D0Z67_RS04100
uniprot id: A0A4P6TQG9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

73044:D0Z67 RS09155
gene id: 73044:D0Z67_RS09155
uniprot id: A0A4P6TV55
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

73044:D0Z67 RS08870
gene id: 73044:D0Z67_RS08870
uniprot id: A0A4P6TV06
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04775
gene id: 73044:D0Z67_RS04775
uniprot id: A0A4P6TQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

73044:D0Z67 RS17305
gene id: 73044:D0Z67_RS17305
uniprot id: A0A4P6TWR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

73044:D0Z67 RS24690
gene id: 73044:D0Z67_RS24690
uniprot id: A0A4P6U1B7
names: Similarity
messages: Belongs to the peptidase M1 family.

73044:D0Z67 RS22930
gene id: 73044:D0Z67_RS22930
uniprot id: A0A4P6TYQ9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

73044:D0Z67 RS18595
gene id: 73044:D0Z67_RS18595
uniprot id: A0A4P6U4K6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS23560
gene id: 73044:D0Z67_RS23560
uniprot id: A0A4P6TZA8
names: Similarity
messages: Belongs to the IucA/IucC family.

73044:D0Z67 RS11780
gene id: 73044:D0Z67_RS11780
uniprot id: A0A4P6TWU3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS17320
gene id: 73044:D0Z67_RS17320
uniprot id: A0A4P6TYF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

73044:D0Z67 RS03245
gene id: 73044:D0Z67_RS03245
uniprot id: A0A4P6TS12
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

73044:D0Z67 RS15705
gene id: 73044:D0Z67_RS15705
uniprot id: A0A4P6TYF7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

73044:D0Z67 RS21020
gene id: 73044:D0Z67_RS21020
uniprot id: A0A4P6TZS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

73044:D0Z67 RS13900
gene id: 73044:D0Z67_RS13900
uniprot id: A0A4P6TUX5
names: Similarity
messages: Belongs to the GARS family.

73044:D0Z67 RS15480
gene id: 73044:D0Z67_RS15480
uniprot id: A0A4P6TXK2
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS11285
gene id: 73044:D0Z67_RS11285
uniprot id: A0A4P6TTR9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

73044:D0Z67 RS03125
gene id: 73044:D0Z67_RS03125
uniprot id: A0A4P6TRZ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS18120
gene id: 73044:D0Z67_RS18120
uniprot id: A0A4P6U1Y6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06885
gene id: 73044:D0Z67_RS06885
uniprot id: A0A4P6TRN1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

73044:D0Z67 RS24960
gene id: 73044:D0Z67_RS24960
uniprot id: A0A4V1A036
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS26440
gene id: 73044:D0Z67_RS26440
uniprot id: A0A4P6U5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

73044:D0Z67 RS05595
gene id: 73044:D0Z67_RS05595
uniprot id: A0A4P6TU82
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

73044:D0Z67 RS26555
gene id: 73044:D0Z67_RS26555
uniprot id: A0A4P6U5M2
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

73044:D0Z67 RS03250
gene id: 73044:D0Z67_RS03250
uniprot id: A0A4P6TS33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS20220
gene id: 73044:D0Z67_RS20220
uniprot id: A0A4P6U0C2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

73044:D0Z67 RS16890
gene id: 73044:D0Z67_RS16890
uniprot id: A0A4P6TW10
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

73044:D0Z67 RS12500
gene id: 73044:D0Z67_RS12500
uniprot id: A0A4P6TWN8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

73044:D0Z67 RS03180
gene id: 73044:D0Z67_RS03180
uniprot id: A0A4P6TSA1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS21910
gene id: 73044:D0Z67_RS21910
uniprot id: A0A4P6U052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS06005
gene id: 73044:D0Z67_RS06005
uniprot id: A0A4P6TTN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

73044:D0Z67 RS20665
gene id: 73044:D0Z67_RS20665
uniprot id: A0A4P6TXY6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS12015
gene id: 73044:D0Z67_RS12015
uniprot id: A0A4P6TU01
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

73044:D0Z67 RS09325
gene id: 73044:D0Z67_RS09325
uniprot id: A0A4P6TUT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

73044:D0Z67 RS21995
gene id: 73044:D0Z67_RS21995
uniprot id: A0A4P6U0L0
names: Similarity
messages: Belongs to the peptidase M1 family.

73044:D0Z67 RS04085
gene id: 73044:D0Z67_RS04085
uniprot id: A0A4V0ZZ21
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS12830
gene id: 73044:D0Z67_RS12830
uniprot id: A0A4P6TUG1
names: Similarity
messages: Belongs to the CutC family.

73044:D0Z67 RS26295
gene id: 73044:D0Z67_RS26295
uniprot id: A0A4P6U2J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

73044:D0Z67 RS23735
gene id: 73044:D0Z67_RS23735
uniprot id: A0A4P6U101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS15085
gene id: 73044:D0Z67_RS15085
uniprot id: A0A4P6TY65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS20125
gene id: 73044:D0Z67_RS20125
uniprot id: A0A4P6TXK3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

73044:D0Z67 RS02060
gene id: 73044:D0Z67_RS02060
uniprot id: A0A4P6TR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

73044:D0Z67 RS08370
gene id: 73044:D0Z67_RS08370
uniprot id: A0A4P6U459
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS21090
gene id: 73044:D0Z67_RS21090
uniprot id: A0A4P6TYF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

73044:D0Z67 RS10510
gene id: 73044:D0Z67_RS10510
uniprot id: A0A4P6TV37
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

73044:D0Z67 RS20865
gene id: 73044:D0Z67_RS20865
uniprot id: A0A4P6U331
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

73044:D0Z67 RS02190
gene id: 73044:D0Z67_RS02190
uniprot id: A0A4P6TUS8
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

73044:D0Z67 RS16475
gene id: 73044:D0Z67_RS16475
uniprot id: A0A4P6TYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

73044:D0Z67 RS16490
gene id: 73044:D0Z67_RS16490
uniprot id: A0A4P6TXS0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

73044:D0Z67 RS19145
gene id: 73044:D0Z67_RS19145
uniprot id: A0A4P6TZV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

73044:D0Z67 RS27290
gene id: 73044:D0Z67_RS27290
uniprot id: A0A4P6U2R9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

73044:D0Z67 RS18785
gene id: 73044:D0Z67_RS18785
uniprot id: A0A4P6U286
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

73044:D0Z67 RS20485
gene id: 73044:D0Z67_RS20485
uniprot id: A0A4P6TXW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

73044:D0Z67 RS14550
gene id: 73044:D0Z67_RS14550
uniprot id: A0A4P6TV78
names: Similarity
messages: Belongs to the ParB family.

73044:D0Z67 RS17085
gene id: 73044:D0Z67_RS17085
uniprot id: A0A4P6TWN1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

73044:D0Z67 RS26545
gene id: 73044:D0Z67_RS26545
uniprot id: A0A4P6U7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

73044:D0Z67 RS11410
gene id: 73044:D0Z67_RS11410
uniprot id: A0A4P6TVR6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

73044:D0Z67 RS22695
gene id: 73044:D0Z67_RS22695
uniprot id: A0A4P6U1H2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

73044:D0Z67 RS22000
gene id: 73044:D0Z67_RS22000
uniprot id: A0A4P6U0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

73044:D0Z67 RS16525
gene id: 73044:D0Z67_RS16525
uniprot id: A0A4P6TY09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS02425
gene id: 73044:D0Z67_RS02425
uniprot id: A0A4P6TPR8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS13520
gene id: 73044:D0Z67_RS13520
uniprot id: A0A4P6TZR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

73044:D0Z67 RS03730
gene id: 73044:D0Z67_RS03730
uniprot id: A0A4P6TSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

73044:D0Z67 RS14455
gene id: 73044:D0Z67_RS14455
uniprot id: A0A4P6TXW8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS20920
gene id: 73044:D0Z67_RS20920
uniprot id: A0A4P6U338
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

73044:D0Z67 RS13260
gene id: 73044:D0Z67_RS13260
uniprot id: A0A4P6TUY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

73044:D0Z67 RS08915
gene id: 73044:D0Z67_RS08915
uniprot id: A0A4P6TVN1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

73044:D0Z67 RS26205
gene id: 73044:D0Z67_RS26205
uniprot id: A0A4P6U264
names: Similarity
messages: Belongs to the universal stress protein A family.

73044:D0Z67 RS27665
gene id: 73044:D0Z67_RS27665
uniprot id: A0A4P6U3Q4
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS23785
gene id: 73044:D0Z67_RS23785
uniprot id: A0A4V1A015
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

73044:D0Z67 RS24270
gene id: 73044:D0Z67_RS24270
uniprot id: A0A4P6U1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

73044:D0Z67 RS28645
gene id: 73044:D0Z67_RS28645
uniprot id: A0A4P6U471
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

73044:D0Z67 RS20660
gene id: 73044:D0Z67_RS20660
uniprot id: A0A4P6U304
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

73044:D0Z67 RS20360
gene id: 73044:D0Z67_RS20360
uniprot id: A0A4P6TXN9
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

73044:D0Z67 RS09590
gene id: 73044:D0Z67_RS09590
uniprot id: A0A4P6TT97
names: Similarity
messages: Belongs to the peptidase M1 family.

73044:D0Z67 RS27775
gene id: 73044:D0Z67_RS27775
uniprot id: A0A4P6U7T8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS11235
gene id: 73044:D0Z67_RS11235
uniprot id: A0A4P6TTQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS06200
gene id: 73044:D0Z67_RS06200
uniprot id: A0A4P6TT36
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

73044:D0Z67 RS03165
gene id: 73044:D0Z67_RS03165
uniprot id: A0A4P6TQC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS21720
gene id: 73044:D0Z67_RS21720
uniprot id: A0A4P6U025
names: Similarity
messages: Belongs to the Dps family.

73044:D0Z67 RS20030
gene id: 73044:D0Z67_RS20030
uniprot id: A0A4V0ZZV0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

73044:D0Z67 RS27200
gene id: 73044:D0Z67_RS27200
uniprot id: A0A4P6U5W8
names: Similarity
messages: Belongs to the peptidase S66 family.

73044:D0Z67 RS08930
gene id: 73044:D0Z67_RS08930
uniprot id: A0A4P6TV15
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS26560
gene id: 73044:D0Z67_RS26560
uniprot id: A0A4P6U0R6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS04275
gene id: 73044:D0Z67_RS04275
uniprot id: A0A4P6TSJ7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS14240
gene id: 73044:D0Z67_RS14240
uniprot id: A0A4P6TXT1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS20005
gene id: 73044:D0Z67_RS20005
uniprot id: A0A4P6U091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

73044:D0Z67 RS17335
gene id: 73044:D0Z67_RS17335
uniprot id: A0A4V0ZZQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

73044:D0Z67 RS14695
gene id: 73044:D0Z67_RS14695
uniprot id: A0A4P6TX72
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS16855
gene id: 73044:D0Z67_RS16855
uniprot id: A0A4P6TWJ2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

73044:D0Z67 RS26310
gene id: 73044:D0Z67_RS26310
uniprot id: A0A4P6U051
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

73044:D0Z67 RS05985
gene id: 73044:D0Z67_RS05985
uniprot id: A0A4P6TRN3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

73044:D0Z67 RS19665
gene id: 73044:D0Z67_RS19665
uniprot id: P80734
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nickel superoxide dismutase family.
messages: Cytoplasm
messages: Homohexamer. The hexameric protein has roughly the shape of a hollow sphere with an outer diameter of 72 Angstroms and a large inner cavity.

73044:D0Z67 RS20945
gene id: 73044:D0Z67_RS20945
uniprot id: A0A4P6U026
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

73044:D0Z67 RS00200
gene id: 73044:D0Z67_RS00200
uniprot id: A0A4P6TQR7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS12060
gene id: 73044:D0Z67_RS12060
uniprot id: A0A4P6TWF8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

73044:D0Z67 RS27115
gene id: 73044:D0Z67_RS27115
uniprot id: A0A4P6U2P1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

73044:D0Z67 RS28120
gene id: 73044:D0Z67_RS28120
uniprot id: A0A4P6U3X6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS26275
gene id: 73044:D0Z67_RS26275
uniprot id: A0A4P6U4L2
names: Similarity
messages: Belongs to the peptidase C40 family.

73044:D0Z67 RS09180
gene id: 73044:D0Z67_RS09180
uniprot id: A0A4P6U429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

73044:D0Z67 RS04470
gene id: 73044:D0Z67_RS04470
uniprot id: A0A4P6TQN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

73044:D0Z67 RS19245
gene id: 73044:D0Z67_RS19245
uniprot id: A0A4P6TXL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS06960
gene id: 73044:D0Z67_RS06960
uniprot id: A0A4V0ZZ72
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

73044:D0Z67 RS01675
gene id: 73044:D0Z67_RS01675
uniprot id: A0A4P6TSH3
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

73044:D0Z67 RS09995
gene id: 73044:D0Z67_RS09995
uniprot id: A0A4P6TT52
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

73044:D0Z67 RS21150
gene id: 73044:D0Z67_RS21150
uniprot id: A0A4P6U0Q3
names: Similarity
messages: Belongs to the DprA/Smf family.

73044:D0Z67 RS05490
gene id: 73044:D0Z67_RS05490
uniprot id: A0A4P6TR18
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS24385
gene id: 73044:D0Z67_RS24385
uniprot id: A0A4P6U2A0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS28650
gene id: 73044:D0Z67_RS28650
uniprot id: A0A4P6U197
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

73044:D0Z67 RS25830
gene id: 73044:D0Z67_RS25830
uniprot id: A0A4P6U2D2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

73044:D0Z67 RS04890
gene id: 73044:D0Z67_RS04890
uniprot id: A0A4P6TSS5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

73044:D0Z67 RS06520
gene id: 73044:D0Z67_RS06520
uniprot id: A0A4P6TWP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

73044:D0Z67 RS10220
gene id: 73044:D0Z67_RS10220
uniprot id: A0A4P6U4V0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS14210
gene id: 73044:D0Z67_RS14210
uniprot id: A0A4P6TUV2
names: Similarity
messages: Belongs to the peptidase M24B family.

73044:D0Z67 RS15950
gene id: 73044:D0Z67_RS15950
uniprot id: A0A4P6TVM4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

73044:D0Z67 RS23680
gene id: 73044:D0Z67_RS23680
uniprot id: A0A4V1A013
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS17745
gene id: 73044:D0Z67_RS17745
uniprot id: A0A4P6U1R9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS15905
gene id: 73044:D0Z67_RS15905
uniprot id: A0A4P6TXI0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

73044:D0Z67 RS17125
gene id: 73044:D0Z67_RS17125
uniprot id: A0A4P6TY17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

73044:D0Z67 RS12570
gene id: 73044:D0Z67_RS12570
uniprot id: A0A4P6TW26
names: Similarity
messages: Belongs to the UPF0309 family.

73044:D0Z67 RS19835
gene id: 73044:D0Z67_RS19835
uniprot id: A0A4P6TZL9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

73044:D0Z67 RS08530
gene id: 73044:D0Z67_RS08530
uniprot id: A0A4V0ZZA0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

73044:D0Z67 RS03560
gene id: 73044:D0Z67_RS03560
uniprot id: A0A4P6TRX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

73044:D0Z67 RS16860
gene id: 73044:D0Z67_RS16860
uniprot id: A0A4P6TYX0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS09365
gene id: 73044:D0Z67_RS09365
uniprot id: A0A4P6TXZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS10885
gene id: 73044:D0Z67_RS10885
uniprot id: A0A4P6TVJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS28440
gene id: 73044:D0Z67_RS28440
uniprot id: A0A4P6U3J1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

73044:D0Z67 RS07160
gene id: 73044:D0Z67_RS07160
uniprot id: A0A4P6TRX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

73044:D0Z67 RS15020
gene id: 73044:D0Z67_RS15020
uniprot id: A0A4P6TVE2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

73044:D0Z67 RS11175
gene id: 73044:D0Z67_RS11175
uniprot id: A0A4P6TYS1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS10520
gene id: 73044:D0Z67_RS10520
uniprot id: A0A4P6TTE1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS02220
gene id: 73044:D0Z67_RS02220
uniprot id: A0A4P6TRM9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

73044:D0Z67 RS16830
gene id: 73044:D0Z67_RS16830
uniprot id: A0A4V0ZZP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS14155
gene id: 73044:D0Z67_RS14155
uniprot id: A0A4P6U012
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS28515
gene id: 73044:D0Z67_RS28515
uniprot id: A0A4P6U454
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS25490
gene id: 73044:D0Z67_RS25490
uniprot id: A0A4P6U2Q6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS14445
gene id: 73044:D0Z67_RS14445
uniprot id: A0A4P6TV60
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

73044:D0Z67 RS17780
gene id: 73044:D0Z67_RS17780
uniprot id: A0A4P6TWG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS02165
gene id: 73044:D0Z67_RS02165
uniprot id: A0A4P6TRM1
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

73044:D0Z67 RS02875
gene id: 73044:D0Z67_RS02875
uniprot id: A0A4P6TQ91
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

73044:D0Z67 RS24925
gene id: 73044:D0Z67_RS24925
uniprot id: A0A4P6U023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS28445
gene id: 73044:D0Z67_RS28445
uniprot id: A0A4P6U3A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

73044:D0Z67 RS25885
gene id: 73044:D0Z67_RS25885
uniprot id: A0A4P6U2D9
names: Similarity
messages: Belongs to the peptidase S33 family.

73044:D0Z67 RS09490
gene id: 73044:D0Z67_RS09490
uniprot id: A0A4P6TUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

73044:D0Z67 RS18755
gene id: 73044:D0Z67_RS18755
uniprot id: A0A4P6TZ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

73044:D0Z67 RS17135
gene id: 73044:D0Z67_RS17135
uniprot id: A0A4P6TWF3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

73044:D0Z67 RS17190
gene id: 73044:D0Z67_RS17190
uniprot id: A0A4P6TWF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

73044:D0Z67 RS25850
gene id: 73044:D0Z67_RS25850
uniprot id: A0A4V1A051
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

73044:D0Z67 RS00745
gene id: 73044:D0Z67_RS00745
uniprot id: A0A4P6TQQ0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

73044:D0Z67 RS02680
gene id: 73044:D0Z67_RS02680
uniprot id: A0A4V0ZYZ7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS07275
gene id: 73044:D0Z67_RS07275
uniprot id: A0A4P6TUY2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

73044:D0Z67 RS07715
gene id: 73044:D0Z67_RS07715
uniprot id: A0A4P6TSF5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06920
gene id: 73044:D0Z67_RS06920
uniprot id: A0A4P6TS28
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS23565
gene id: 73044:D0Z67_RS23565
uniprot id: A0A4P6TZR6
names: Similarity
messages: Belongs to the IucA/IucC family.

73044:D0Z67 RS24965
gene id: 73044:D0Z67_RS24965
uniprot id: A0A4P6U1L6
names: Similarity
messages: Belongs to the barstar family.

73044:D0Z67 RS15295
gene id: 73044:D0Z67_RS15295
uniprot id: A0A4V0ZZL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS14380
gene id: 73044:D0Z67_RS14380
uniprot id: A0A4P6TWU1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

73044:D0Z67 RS04975
gene id: 73044:D0Z67_RS04975
uniprot id: A0A4V0ZZ37
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS21395
gene id: 73044:D0Z67_RS21395
uniprot id: A0A4P6U0A9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS26740
gene id: 73044:D0Z67_RS26740
uniprot id: A0A4P6U567
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

73044:D0Z67 RS04955
gene id: 73044:D0Z67_RS04955
uniprot id: A0A4P6TST4
names: Similarity
messages: Belongs to the glutamine synthetase family.

73044:D0Z67 RS23910
gene id: 73044:D0Z67_RS23910
uniprot id: A0A4P6TZG2
names: Similarity
messages: Belongs to the peptidase S1 family.

73044:D0Z67 RS18365
gene id: 73044:D0Z67_RS18365
uniprot id: A0A4P6TYY2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

73044:D0Z67 RS21095
gene id: 73044:D0Z67_RS21095
uniprot id: A0A4P6U0P1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

73044:D0Z67 RS07880
gene id: 73044:D0Z67_RS07880
uniprot id: A0A4P6TS89
names: Similarity
messages: Belongs to the glutamine synthetase family.

73044:D0Z67 RS22445
gene id: 73044:D0Z67_RS22445
uniprot id: A0A4P6U0T6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03025
gene id: 73044:D0Z67_RS03025
uniprot id: A0A4P6TQ00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

73044:D0Z67 RS26095
gene id: 73044:D0Z67_RS26095
uniprot id: A0A4P6U249
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

73044:D0Z67 RS26180
gene id: 73044:D0Z67_RS26180
uniprot id: A0A4P6U2I2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS19885
gene id: 73044:D0Z67_RS19885
uniprot id: A0A4P6U074
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

73044:D0Z67 RS04105
gene id: 73044:D0Z67_RS04105
uniprot id: A0A4P6TQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

73044:D0Z67 RS17010
gene id: 73044:D0Z67_RS17010
uniprot id: A0A4P6TWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

73044:D0Z67 RS05800
gene id: 73044:D0Z67_RS05800
uniprot id: A0A4P6TUB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

73044:D0Z67 RS00800
gene id: 73044:D0Z67_RS00800
uniprot id: A0A4V1A0A7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

73044:D0Z67 RS07190
gene id: 73044:D0Z67_RS07190
uniprot id: A0A4P6TRT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

73044:D0Z67 RS17140
gene id: 73044:D0Z67_RS17140
uniprot id: A0A4P6TWP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

73044:D0Z67 RS13365
gene id: 73044:D0Z67_RS13365
uniprot id: A0A4P6TZN7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS10655
gene id: 73044:D0Z67_RS10655
uniprot id: A0A4P6TTR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

73044:D0Z67 RS17200
gene id: 73044:D0Z67_RS17200
uniprot id: A0A4P6TZ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

73044:D0Z67 RS17235
gene id: 73044:D0Z67_RS17235
uniprot id: A0A4P6U1I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

73044:D0Z67 RS17310
gene id: 73044:D0Z67_RS17310
uniprot id: A0A4P6TZ39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

73044:D0Z67 RS08190
gene id: 73044:D0Z67_RS08190
uniprot id: A0A4P6TUN6
names: Similarity
messages: Belongs to the UPF0246 family.

73044:D0Z67 RS02065
gene id: 73044:D0Z67_RS02065
uniprot id: A0A4P6TUR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

73044:D0Z67 RS06480
gene id: 73044:D0Z67_RS06480
uniprot id: A0A4P6TRV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

73044:D0Z67 RS03915
gene id: 73044:D0Z67_RS03915
uniprot id: A0A4P6TQD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MSOX/MTOX family. MSOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of sarcosine.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS18740
gene id: 73044:D0Z67_RS18740
uniprot id: A0A4P6TX50
names: Similarity
messages: Belongs to the FBPase class 2 family.

73044:D0Z67 RS11825
gene id: 73044:D0Z67_RS11825
uniprot id: A0A4P6TUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

73044:D0Z67 RS15915
gene id: 73044:D0Z67_RS15915
uniprot id: A0A4P6TVU4
names: Similarity
messages: Belongs to the GSP E family.

73044:D0Z67 RS25800
gene id: 73044:D0Z67_RS25800
uniprot id: A0A4V1A050
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS17735
gene id: 73044:D0Z67_RS17735
uniprot id: A0A4V0ZZQ9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

73044:D0Z67 RS28380
gene id: 73044:D0Z67_RS28380
uniprot id: A0A4P6U3I4
names: Similarity
messages: Belongs to the group II decarboxylase family.

73044:D0Z67 RS14960
gene id: 73044:D0Z67_RS14960
uniprot id: A0A4P6TVN7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

73044:D0Z67 RS06195
gene id: 73044:D0Z67_RS06195
uniprot id: A0A4V0ZZ58
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

73044:D0Z67 RS17975
gene id: 73044:D0Z67_RS17975
uniprot id: A0A4P6TYQ6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

73044:D0Z67 RS08350
gene id: 73044:D0Z67_RS08350
uniprot id: A0A4P6TUR8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS27955
gene id: 73044:D0Z67_RS27955
uniprot id: A0A4V1A087
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07940
gene id: 73044:D0Z67_RS07940
uniprot id: A0A4P6TS98
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

73044:D0Z67 RS09265
gene id: 73044:D0Z67_RS09265
uniprot id: A0A4P6TUS6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

73044:D0Z67 RS16010
gene id: 73044:D0Z67_RS16010
uniprot id: A0A4P6TVN2
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

73044:D0Z67 RS18910
gene id: 73044:D0Z67_RS18910
uniprot id: A0A4P6U2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS23845
gene id: 73044:D0Z67_RS23845
uniprot id: A0A4P6U4G0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

73044:D0Z67 RS05610
gene id: 73044:D0Z67_RS05610
uniprot id: A0A4P6TT63
names: Similarity
messages: Belongs to the peptidase S1 family.

73044:D0Z67 RS06180
gene id: 73044:D0Z67_RS06180
uniprot id: A0A4P6U6Z1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

73044:D0Z67 RS10245
gene id: 73044:D0Z67_RS10245
uniprot id: A0A4P6TV00
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

73044:D0Z67 RS05425
gene id: 73044:D0Z67_RS05425
uniprot id: A0A4P6U4M8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS21330
gene id: 73044:D0Z67_RS21330
uniprot id: A0A4P6U0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS15320
gene id: 73044:D0Z67_RS15320
uniprot id: A0A4P6TXH5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06240
gene id: 73044:D0Z67_RS06240
uniprot id: A0A4P6TRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS10665
gene id: 73044:D0Z67_RS10665
uniprot id: A0A4P6TVF5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS16550
gene id: 73044:D0Z67_RS16550
uniprot id: A0A4P6U174
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

73044:D0Z67 RS16075
gene id: 73044:D0Z67_RS16075
uniprot id: A0A4P6TVP2
names: Similarity
messages: Belongs to the UPF0145 family.

73044:D0Z67 RS07500
gene id: 73044:D0Z67_RS07500
uniprot id: A0A4P6TTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

73044:D0Z67 RS23710
gene id: 73044:D0Z67_RS23710
uniprot id: A0A4P6U1G1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

73044:D0Z67 RS02445
gene id: 73044:D0Z67_RS02445
uniprot id: A0A4P6TRR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

73044:D0Z67 RS18995
gene id: 73044:D0Z67_RS18995
uniprot id: A0A4P6TX38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS17245
gene id: 73044:D0Z67_RS17245
uniprot id: A0A4P6TWQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

73044:D0Z67 RS04635
gene id: 73044:D0Z67_RS04635
uniprot id: A0A4P6TT00
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

73044:D0Z67 RS14295
gene id: 73044:D0Z67_RS14295
uniprot id: A0A4P6TXU1
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

73044:D0Z67 RS16730
gene id: 73044:D0Z67_RS16730
uniprot id: A0A4V0ZZP1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

73044:D0Z67 RS27315
gene id: 73044:D0Z67_RS27315
uniprot id: A0A4P6U5Y6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS10750
gene id: 73044:D0Z67_RS10750
uniprot id: A0A4P6TV79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

73044:D0Z67 RS28375
gene id: 73044:D0Z67_RS28375
uniprot id: A0A4P6U3T4
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

73044:D0Z67 RS11450
gene id: 73044:D0Z67_RS11450
uniprot id: A0A4P6TWN5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

73044:D0Z67 RS09085
gene id: 73044:D0Z67_RS09085
uniprot id: A0A4P6TVQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

73044:D0Z67 RS07235
gene id: 73044:D0Z67_RS07235
uniprot id: A0A4P6TTT6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS26340
gene id: 73044:D0Z67_RS26340
uniprot id: A0A4P6U0Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS12180
gene id: 73044:D0Z67_RS12180
uniprot id: A0A4P6TU64
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS22705
gene id: 73044:D0Z67_RS22705
uniprot id: A0A4V0ZZZ6
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

73044:D0Z67 RS03725
gene id: 73044:D0Z67_RS03725
uniprot id: A0A4P6TSA4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

73044:D0Z67 RS03605
gene id: 73044:D0Z67_RS03605
uniprot id: A0A4P6TQ92
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

73044:D0Z67 RS28045
gene id: 73044:D0Z67_RS28045
uniprot id: A0A4P6U1N5
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS05965
gene id: 73044:D0Z67_RS05965
uniprot id: A0A4P6TT06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

73044:D0Z67 RS17750
gene id: 73044:D0Z67_RS17750
uniprot id: A0A4P6TWP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

73044:D0Z67 RS06745
gene id: 73044:D0Z67_RS06745
uniprot id: A0A4P6TS07
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS00160
gene id: 73044:D0Z67_RS00160
uniprot id: A0A4V0ZYV4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04245
gene id: 73044:D0Z67_RS04245
uniprot id: A0A4P6U1L8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS17015
gene id: 73044:D0Z67_RS17015
uniprot id: A0A4P6TWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS13830
gene id: 73044:D0Z67_RS13830
uniprot id: A0A4P6TUW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

73044:D0Z67 RS09855
gene id: 73044:D0Z67_RS09855
uniprot id: A0A4P6TY77
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

73044:D0Z67 RS25640
gene id: 73044:D0Z67_RS25640
uniprot id: A0A4P6U580
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

73044:D0Z67 RS17805
gene id: 73044:D0Z67_RS17805
uniprot id: A0A4P6TWZ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS10115
gene id: 73044:D0Z67_RS10115
uniprot id: A0A4P6TV64
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

73044:D0Z67 RS19925
gene id: 73044:D0Z67_RS19925
uniprot id: A0A4P6TZB7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

73044:D0Z67 RS03530
gene id: 73044:D0Z67_RS03530
uniprot id: A0A4P6TS58
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS04335
gene id: 73044:D0Z67_RS04335
uniprot id: A0A4P6TSU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS10745
gene id: 73044:D0Z67_RS10745
uniprot id: A0A4V0ZZD8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS28000
gene id: 73044:D0Z67_RS28000
uniprot id: A0A4P6U332
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

73044:D0Z67 RS19955
gene id: 73044:D0Z67_RS19955
uniprot id: A0A4P6TZL7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

73044:D0Z67 RS11830
gene id: 73044:D0Z67_RS11830
uniprot id: A0A4P6TWV4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

73044:D0Z67 RS23090
gene id: 73044:D0Z67_RS23090
uniprot id: A0A4P6U1N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS21705
gene id: 73044:D0Z67_RS21705
uniprot id: A0A4P6U114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

73044:D0Z67 RS17365
gene id: 73044:D0Z67_RS17365
uniprot id: A0A4P6TYG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

73044:D0Z67 RS12505
gene id: 73044:D0Z67_RS12505
uniprot id: A0A4P6TU62
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS25845
gene id: 73044:D0Z67_RS25845
uniprot id: A0A4P6TZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

73044:D0Z67 RS06645
gene id: 73044:D0Z67_RS06645
uniprot id: A0A4P6TTK9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

73044:D0Z67 RS21745
gene id: 73044:D0Z67_RS21745
uniprot id: A0A4P6U0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

73044:D0Z67 RS22765
gene id: 73044:D0Z67_RS22765
uniprot id: A0A4P6U0K4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS18555
gene id: 73044:D0Z67_RS18555
uniprot id: A0A4P6TYP4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

73044:D0Z67 RS27930
gene id: 73044:D0Z67_RS27930
uniprot id: A0A4P6U3L0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

73044:D0Z67 RS21565
gene id: 73044:D0Z67_RS21565
uniprot id: A0A4P6U100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS11295
gene id: 73044:D0Z67_RS11295
uniprot id: A0A4P6TWK8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS11565
gene id: 73044:D0Z67_RS11565
uniprot id: A0A4P6TWQ6
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

73044:D0Z67 RS23625
gene id: 73044:D0Z67_RS23625
uniprot id: A0A4P6TZ09
names: Similarity
messages: Belongs to the malate synthase family.

73044:D0Z67 RS17515
gene id: 73044:D0Z67_RS17515
uniprot id: A0A4P6U1N2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS20875
gene id: 73044:D0Z67_RS20875
uniprot id: A0A4P6TYB8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

73044:D0Z67 RS02275
gene id: 73044:D0Z67_RS02275
uniprot id: A0A4P6TRN5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

73044:D0Z67 RS08825
gene id: 73044:D0Z67_RS08825
uniprot id: A0A4V0ZZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS22010
gene id: 73044:D0Z67_RS22010
uniprot id: A0A4P6U156
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS20375
gene id: 73044:D0Z67_RS20375
uniprot id: A0A4P6U2V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

73044:D0Z67 RS28205
gene id: 73044:D0Z67_RS28205
uniprot id: A0A4P6U1E3
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS05620
gene id: 73044:D0Z67_RS05620
uniprot id: A0A4P6TR41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS27865
gene id: 73044:D0Z67_RS27865
uniprot id: A0A4P6U190
names: Similarity
messages: Belongs to the peptidase S1 family.

73044:D0Z67 RS16165
gene id: 73044:D0Z67_RS16165
uniprot id: A0A4P6TXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS30405
gene id: 73044:D0Z67_RS30405
uniprot id: A0A4P6TX82
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS20940
gene id: 73044:D0Z67_RS20940
uniprot id: A0A4P6U031
names: Similarity
messages: Belongs to the heat shock protein 90 family.

73044:D0Z67 RS16970
gene id: 73044:D0Z67_RS16970
uniprot id: A0A4P6TYZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

73044:D0Z67 RS24585
gene id: 73044:D0Z67_RS24585
uniprot id: A0A4P6U274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

73044:D0Z67 RS11300
gene id: 73044:D0Z67_RS11300
uniprot id: A0A4P6TVR4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

73044:D0Z67 RS09540
gene id: 73044:D0Z67_RS09540
uniprot id: A0A4P6TT88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

73044:D0Z67 RS06535
gene id: 73044:D0Z67_RS06535
uniprot id: A0A4P6TUM9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS24730
gene id: 73044:D0Z67_RS24730
uniprot id: A0A4P6TZI4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

73044:D0Z67 RS23330
gene id: 73044:D0Z67_RS23330
uniprot id: A0A4P6U479
names: Cofactor
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS25150
gene id: 73044:D0Z67_RS25150
uniprot id: A0A4P6U513
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS14830
gene id: 73044:D0Z67_RS14830
uniprot id: A0A4P6U2C3
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

73044:D0Z67 RS00805
gene id: 73044:D0Z67_RS00805
uniprot id: A0A4P6U3P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

73044:D0Z67 RS00785
gene id: 73044:D0Z67_RS00785
uniprot id: A0A4V0ZYW5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

73044:D0Z67 RS21820
gene id: 73044:D0Z67_RS21820
uniprot id: A0A4P6U134
names: Similarity
messages: Belongs to the amidinotransferase family.

73044:D0Z67 RS19990
gene id: 73044:D0Z67_RS19990
uniprot id: A0A4P6U2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

73044:D0Z67 RS22700
gene id: 73044:D0Z67_RS22700
uniprot id: A0A4P6TYN1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

73044:D0Z67 RS17550
gene id: 73044:D0Z67_RS17550
uniprot id: A0A4P6TWC5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

73044:D0Z67 RS02580
gene id: 73044:D0Z67_RS02580
uniprot id: A0A4P6TRG3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

73044:D0Z67 RS16460
gene id: 73044:D0Z67_RS16460
uniprot id: A0A4P6TYR7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS22350
gene id: 73044:D0Z67_RS22350
uniprot id: A0A4P6U1B1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07935
gene id: 73044:D0Z67_RS07935
uniprot id: A0A4P6TXB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

73044:D0Z67 RS16930
gene id: 73044:D0Z67_RS16930
uniprot id: A0A4P6TY82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

73044:D0Z67 RS28700
gene id: 73044:D0Z67_RS28700
uniprot id: A0A4P6U1A4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

73044:D0Z67 RS20385
gene id: 73044:D0Z67_RS20385
uniprot id: A0A4P6TY38
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS20475
gene id: 73044:D0Z67_RS20475
uniprot id: A0A4P6TZK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS19010
gene id: 73044:D0Z67_RS19010
uniprot id: A0A4P6TYX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

73044:D0Z67 RS16480
gene id: 73044:D0Z67_RS16480
uniprot id: A0A4P6TVV1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

73044:D0Z67 RS09445
gene id: 73044:D0Z67_RS09445
uniprot id: A0A4P6TUW0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

73044:D0Z67 RS24755
gene id: 73044:D0Z67_RS24755
uniprot id: A0A4P6U099
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

73044:D0Z67 RS17460
gene id: 73044:D0Z67_RS17460
uniprot id: A0A4P6TWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS20400
gene id: 73044:D0Z67_RS20400
uniprot id: A0A4P6TZT9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS10445
gene id: 73044:D0Z67_RS10445
uniprot id: A0A4P6TYG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS02520
gene id: 73044:D0Z67_RS02520
uniprot id: A0A4V0ZYZ4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08845
gene id: 73044:D0Z67_RS08845
uniprot id: A0A4P6TSN3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS08680
gene id: 73044:D0Z67_RS08680
uniprot id: A0A4P6TUI6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS26595
gene id: 73044:D0Z67_RS26595
uniprot id: A0A4V1A064
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS16625
gene id: 73044:D0Z67_RS16625
uniprot id: A0A4P6U183
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS21170
gene id: 73044:D0Z67_RS21170
uniprot id: A0A4P6U0S9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

73044:D0Z67 RS20980
gene id: 73044:D0Z67_RS20980
uniprot id: A0A4P6TYD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

73044:D0Z67 RS06430
gene id: 73044:D0Z67_RS06430
uniprot id: A0A4P6TUK8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

73044:D0Z67 RS13485
gene id: 73044:D0Z67_RS13485
uniprot id: A0A4P6TXH8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

73044:D0Z67 RS01355
gene id: 73044:D0Z67_RS01355
uniprot id: A0A4P6TPL5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS24570
gene id: 73044:D0Z67_RS24570
uniprot id: A0A4P6U4S4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

73044:D0Z67 RS21180
gene id: 73044:D0Z67_RS21180
uniprot id: A0A4V0ZZX0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS13370
gene id: 73044:D0Z67_RS13370
uniprot id: A0A4P6TUP5
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

73044:D0Z67 RS10910
gene id: 73044:D0Z67_RS10910
uniprot id: A0A4V0ZZE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

73044:D0Z67 RS15585
gene id: 73044:D0Z67_RS15585
uniprot id: A0A4P6TVY7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS20725
gene id: 73044:D0Z67_RS20725
uniprot id: A0A4P6TXZ8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04220
gene id: 73044:D0Z67_RS04220
uniprot id: A0A4P6TSI6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

73044:D0Z67 RS07850
gene id: 73044:D0Z67_RS07850
uniprot id: A0A4P6TU41
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS13540
gene id: 73044:D0Z67_RS13540
uniprot id: A0A4P6TWQ2
names: Similarity
messages: Belongs to the peptidase C40 family.

73044:D0Z67 RS20715
gene id: 73044:D0Z67_RS20715
uniprot id: A0A4P6TZM8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS25130
gene id: 73044:D0Z67_RS25130
uniprot id: A0A4P6U2K5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS15715
gene id: 73044:D0Z67_RS15715
uniprot id: A0A4P6TXN5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

73044:D0Z67 RS08390
gene id: 73044:D0Z67_RS08390
uniprot id: A0A4P6TSR4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

73044:D0Z67 RS13005
gene id: 73044:D0Z67_RS13005
uniprot id: A0A4P6TUI9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

73044:D0Z67 RS09070
gene id: 73044:D0Z67_RS09070
uniprot id: A0A4P6TXU5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS25010
gene id: 73044:D0Z67_RS25010
uniprot id: A0A4P6U2I8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

73044:D0Z67 RS19460
gene id: 73044:D0Z67_RS19460
uniprot id: A0A4V0ZZU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

73044:D0Z67 RS20720
gene id: 73044:D0Z67_RS20720
uniprot id: A0A4P6U313
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

73044:D0Z67 RS19085
gene id: 73044:D0Z67_RS19085
uniprot id: A0A4P6TX98
names: Similarity
messages: Belongs to the LOG family.

73044:D0Z67 RS02650
gene id: 73044:D0Z67_RS02650
uniprot id: A0A4P6TQ57
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS17400
gene id: 73044:D0Z67_RS17400
uniprot id: A0A4P6TWI8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS05630
gene id: 73044:D0Z67_RS05630
uniprot id: A0A4P6TSV8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

73044:D0Z67 RS05615
gene id: 73044:D0Z67_RS05615
uniprot id: A0A4P6TTH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

73044:D0Z67 RS24285
gene id: 73044:D0Z67_RS24285
uniprot id: A0A4P6TZC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS22960
gene id: 73044:D0Z67_RS22960
uniprot id: A0A4P6TZC8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

73044:D0Z67 RS05025
gene id: 73044:D0Z67_RS05025
uniprot id: A0A4V0ZZ38
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

73044:D0Z67 RS22210
gene id: 73044:D0Z67_RS22210
uniprot id: A0A4P6TYN0
names: Similarity
messages: Belongs to the citrate synthase family.

73044:D0Z67 RS05905
gene id: 73044:D0Z67_RS05905
uniprot id: A0A4P6TR82
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS19650
gene id: 73044:D0Z67_RS19650
uniprot id: A0A4P6TXI7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

73044:D0Z67 RS09455
gene id: 73044:D0Z67_RS09455
uniprot id: A0A4P6TSX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

73044:D0Z67 RS28470
gene id: 73044:D0Z67_RS28470
uniprot id: A0A4P6U3F7
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

73044:D0Z67 RS06260
gene id: 73044:D0Z67_RS06260
uniprot id: A0A4P6TRI2
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

73044:D0Z67 RS25050
gene id: 73044:D0Z67_RS25050
uniprot id: A0A4P6U041
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

73044:D0Z67 RS22525
gene id: 73044:D0Z67_RS22525
uniprot id: A0A4P6U0E7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS05735
gene id: 73044:D0Z67_RS05735
uniprot id: A0A4P6TWE0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS05675
gene id: 73044:D0Z67_RS05675
uniprot id: A0A4V0ZZ49
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

73044:D0Z67 RS09380
gene id: 73044:D0Z67_RS09380
uniprot id: A0A4P6TVU0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS06350
gene id: 73044:D0Z67_RS06350
uniprot id: A0A4P6TRE4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

73044:D0Z67 RS20675
gene id: 73044:D0Z67_RS20675
uniprot id: A0A4P6U0I4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS21195
gene id: 73044:D0Z67_RS21195
uniprot id: A0A4P6U386
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

73044:D0Z67 RS18415
gene id: 73044:D0Z67_RS18415
uniprot id: A0A4P6TZK1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

73044:D0Z67 RS28845
gene id: 73044:D0Z67_RS28845
uniprot id: A0A4P6U3Z2
names: Similarity
messages: Belongs to the asp23 family.

73044:D0Z67 RS04380
gene id: 73044:D0Z67_RS04380
uniprot id: A0A4P6TSJ8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

73044:D0Z67 RS28825
gene id: 73044:D0Z67_RS28825
uniprot id: A0A4P6U3K4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS22220
gene id: 73044:D0Z67_RS22220
uniprot id: A0A4P6U158
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

73044:D0Z67 RS15710
gene id: 73044:D0Z67_RS15710
uniprot id: A0A4P6TXP0
names: Similarity
messages: Belongs to the UPF0166 family.

73044:D0Z67 RS17040
gene id: 73044:D0Z67_RS17040
uniprot id: A0A4P6TW42
names: Similarity
messages: Belongs to the UPF0234 family.

73044:D0Z67 RS07475
gene id: 73044:D0Z67_RS07475
uniprot id: A0A4P6TTP5
names: Similarity
messages: Belongs to the arsA ATPase family.

73044:D0Z67 RS09370
gene id: 73044:D0Z67_RS09370
uniprot id: A0A4P6TSW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

73044:D0Z67 RS19105
gene id: 73044:D0Z67_RS19105
uniprot id: A0A4P6TZA3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

73044:D0Z67 RS16080
gene id: 73044:D0Z67_RS16080
uniprot id: A0A4V0ZZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

73044:D0Z67 RS11230
gene id: 73044:D0Z67_RS11230
uniprot id: A0A4P6TYS8
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

73044:D0Z67 RS14070
gene id: 73044:D0Z67_RS14070
uniprot id: A0A4P6U795
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09480
gene id: 73044:D0Z67_RS09480
uniprot id: A0A4P6TT78
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

73044:D0Z67 RS13955
gene id: 73044:D0Z67_RS13955
uniprot id: A0A4P6TUS3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

73044:D0Z67 RS06450
gene id: 73044:D0Z67_RS06450
uniprot id: A0A4P6TRF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS24675
gene id: 73044:D0Z67_RS24675
uniprot id: A0A4P6U4I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

73044:D0Z67 RS11630
gene id: 73044:D0Z67_RS11630
uniprot id: A0A4P6TVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

73044:D0Z67 RS14320
gene id: 73044:D0Z67_RS14320
uniprot id: A0A4V0ZZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

73044:D0Z67 RS15390
gene id: 73044:D0Z67_RS15390
uniprot id: A0A4P6TVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

73044:D0Z67 RS23010
gene id: 73044:D0Z67_RS23010
uniprot id: A0A4P6TZ14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

73044:D0Z67 RS17875
gene id: 73044:D0Z67_RS17875
uniprot id: A0A4P6TYQ7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07045
gene id: 73044:D0Z67_RS07045
uniprot id: A0A4P6TRW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

73044:D0Z67 RS05645
gene id: 73044:D0Z67_RS05645
uniprot id: A0A4P6TRI4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

73044:D0Z67 RS00110
gene id: 73044:D0Z67_RS00110
uniprot id: A0A4V0ZYV3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

73044:D0Z67 RS23880
gene id: 73044:D0Z67_RS23880
uniprot id: A0A4P6U198
names: Similarity
messages: Belongs to the CdaR family.

73044:D0Z67 RS27965
gene id: 73044:D0Z67_RS27965
uniprot id: A0A4P6U691
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

73044:D0Z67 RS29415
gene id: 73044:D0Z67_RS29415
uniprot id: A0A4P6U500
names: Similarity
messages: Belongs to the ParB family.

73044:D0Z67 RS04645
gene id: 73044:D0Z67_RS04645
uniprot id: A0A4V0ZZ31
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

73044:D0Z67 RS25290
gene id: 73044:D0Z67_RS25290
uniprot id: A0A4P6U252
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS21920
gene id: 73044:D0Z67_RS21920
uniprot id: A0A4P6TYI1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

73044:D0Z67 RS02905
gene id: 73044:D0Z67_RS02905
uniprot id: A0A4P6TPY2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

73044:D0Z67 RS13735
gene id: 73044:D0Z67_RS13735
uniprot id: A0A4P6TXE2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09470
gene id: 73044:D0Z67_RS09470
uniprot id: A0A4P6TY16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

73044:D0Z67 RS16305
gene id: 73044:D0Z67_RS16305
uniprot id: A0A4P6TXP5
names: Similarity
messages: Belongs to the Nth/MutY family.

73044:D0Z67 RS08795
gene id: 73044:D0Z67_RS08795
uniprot id: A0A4P6TSX2
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

73044:D0Z67 RS23120
gene id: 73044:D0Z67_RS23120
uniprot id: A0A4P6TZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

73044:D0Z67 RS26100
gene id: 73044:D0Z67_RS26100
uniprot id: A0A4P6U5E4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

73044:D0Z67 RS28805
gene id: 73044:D0Z67_RS28805
uniprot id: A0A4P6U3E6
names: Similarity
messages: Belongs to the CFA/CMAS family.

73044:D0Z67 RS19035
gene id: 73044:D0Z67_RS19035
uniprot id: A0A4P6TZ95
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS14345
gene id: 73044:D0Z67_RS14345
uniprot id: A0A4P6TXV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

73044:D0Z67 RS20860
gene id: 73044:D0Z67_RS20860
uniprot id: A0A4P6TZP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

73044:D0Z67 RS23075
gene id: 73044:D0Z67_RS23075
uniprot id: A0A4P6U119
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

73044:D0Z67 RS17415
gene id: 73044:D0Z67_RS17415
uniprot id: A0A4P6TYH1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

73044:D0Z67 RS17300
gene id: 73044:D0Z67_RS17300
uniprot id: A0A4P6TWH6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

73044:D0Z67 RS23850
gene id: 73044:D0Z67_RS23850
uniprot id: A0A4P6TZF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

73044:D0Z67 RS21240
gene id: 73044:D0Z67_RS21240
uniprot id: A0A4P6U4Q2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS11900
gene id: 73044:D0Z67_RS11900
uniprot id: A0A4P6TTY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS12225
gene id: 73044:D0Z67_RS12225
uniprot id: A0A4P6TVW0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

73044:D0Z67 RS27710
gene id: 73044:D0Z67_RS27710
uniprot id: A0A4P6U374
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS12465
gene id: 73044:D0Z67_RS12465
uniprot id: A0A4P6TW01
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

73044:D0Z67 RS01375
gene id: 73044:D0Z67_RS01375
uniprot id: A0A4P6TRH2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

73044:D0Z67 RS09250
gene id: 73044:D0Z67_RS09250
uniprot id: A0A4P6TVS2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS16795
gene id: 73044:D0Z67_RS16795
uniprot id: A0A4P6TW89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS14435
gene id: 73044:D0Z67_RS14435
uniprot id: A0A4P6U061
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

73044:D0Z67 RS12380
gene id: 73044:D0Z67_RS12380
uniprot id: A0A4P6TW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

73044:D0Z67 RS05990
gene id: 73044:D0Z67_RS05990
uniprot id: A0A4P6TUD8
names: Similarity
messages: Belongs to the peptidase U62 family.

73044:D0Z67 RS23095
gene id: 73044:D0Z67_RS23095
uniprot id: A0A4P6TYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS02560
gene id: 73044:D0Z67_RS02560
uniprot id: A0A4P6TRT4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

73044:D0Z67 RS21965
gene id: 73044:D0Z67_RS21965
uniprot id: A0A4P6U3K8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

73044:D0Z67 RS24840
gene id: 73044:D0Z67_RS24840
uniprot id: A0A4P6U1J7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS07755
gene id: 73044:D0Z67_RS07755
uniprot id: A0A4P6TTU1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

73044:D0Z67 RS28965
gene id: 73044:D0Z67_RS28965
uniprot id: A0A4P6U3S4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS17150
gene id: 73044:D0Z67_RS17150
uniprot id: A0A4P6TYC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

73044:D0Z67 RS22905
gene id: 73044:D0Z67_RS22905
uniprot id: A0A4P6TZB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

73044:D0Z67 RS22125
gene id: 73044:D0Z67_RS22125
uniprot id: A0A4P6U5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

73044:D0Z67 RS09665
gene id: 73044:D0Z67_RS09665
uniprot id: A0A4P6TT10
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

73044:D0Z67 RS19170
gene id: 73044:D0Z67_RS19170
uniprot id: A0A4P6TX63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

73044:D0Z67 RS07945
gene id: 73044:D0Z67_RS07945
uniprot id: A0A4P6TSJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

73044:D0Z67 RS02110
gene id: 73044:D0Z67_RS02110
uniprot id: A0A4P6TPL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS04640
gene id: 73044:D0Z67_RS04640
uniprot id: A0A4P6TQN9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

73044:D0Z67 RS10530
gene id: 73044:D0Z67_RS10530
uniprot id: A0A4P6TWA4
names: Similarity
messages: Belongs to the UPF0303 family.

73044:D0Z67 RS24290
gene id: 73044:D0Z67_RS24290
uniprot id: A0A4V1A024
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS17130
gene id: 73044:D0Z67_RS17130
uniprot id: A0A4P6U1G6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

73044:D0Z67 RS27275
gene id: 73044:D0Z67_RS27275
uniprot id: A0A4P6U1C0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

73044:D0Z67 RS03320
gene id: 73044:D0Z67_RS03320
uniprot id: A0A4V0ZZ08
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS14535
gene id: 73044:D0Z67_RS14535
uniprot id: A0A4V0ZZK3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

73044:D0Z67 RS17535
gene id: 73044:D0Z67_RS17535
uniprot id: A0A4P6TYI5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

73044:D0Z67 RS13515
gene id: 73044:D0Z67_RS13515
uniprot id: A0A4P6TWG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

73044:D0Z67 RS05660
gene id: 73044:D0Z67_RS05660
uniprot id: A0A4P6TT66
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

73044:D0Z67 RS19800
gene id: 73044:D0Z67_RS19800
uniprot id: A0A4P6TXE8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

73044:D0Z67 RS18875
gene id: 73044:D0Z67_RS18875
uniprot id: A0A4P6TZR0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

73044:D0Z67 RS11735
gene id: 73044:D0Z67_RS11735
uniprot id: A0A4P6TVY4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03215
gene id: 73044:D0Z67_RS03215
uniprot id: A0A4P6U1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

73044:D0Z67 RS17370
gene id: 73044:D0Z67_RS17370
uniprot id: A0A4P6TYG4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

73044:D0Z67 RS04455
gene id: 73044:D0Z67_RS04455
uniprot id: A0A4V0ZZ28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

73044:D0Z67 RS23775
gene id: 73044:D0Z67_RS23775
uniprot id: A0A4P6U1Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

73044:D0Z67 RS14690
gene id: 73044:D0Z67_RS14690
uniprot id: A0A4P6TX68
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

73044:D0Z67 RS23430
gene id: 73044:D0Z67_RS23430
uniprot id: A0A4V1A009
names: Similarity
messages: Belongs to the CdaR family.

73044:D0Z67 RS11845
gene id: 73044:D0Z67_RS11845
uniprot id: A0A4P6TWC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

73044:D0Z67 RS07700
gene id: 73044:D0Z67_RS07700
uniprot id: A0A4P6TTT2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

73044:D0Z67 RS11190
gene id: 73044:D0Z67_RS11190
uniprot id: A0A4P6TWJ4
names: Similarity
messages: Belongs to the UPF0434 family.

73044:D0Z67 RS06025
gene id: 73044:D0Z67_RS06025
uniprot id: A0A4P6TWI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

73044:D0Z67 RS28970
gene id: 73044:D0Z67_RS28970
uniprot id: A0A4P6U3H2
names: Similarity
messages: Belongs to the catalase family.

73044:D0Z67 RS18570
gene id: 73044:D0Z67_RS18570
uniprot id: A0A4P6TXB3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS01655
gene id: 73044:D0Z67_RS01655
uniprot id: A0A4P6TR20
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

73044:D0Z67 RS16145
gene id: 73044:D0Z67_RS16145
uniprot id: A0A4P6U456
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

73044:D0Z67 RS14515
gene id: 73044:D0Z67_RS14515
uniprot id: A0A4P6TX41
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07430
gene id: 73044:D0Z67_RS07430
uniprot id: A0A4P6TS18
names: Similarity
messages: Belongs to the ice-binding protein family.

73044:D0Z67 RS21155
gene id: 73044:D0Z67_RS21155
uniprot id: A0A4P6U068
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

73044:D0Z67 RS04355
gene id: 73044:D0Z67_RS04355
uniprot id: A0A4P6TSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

73044:D0Z67 RS18115
gene id: 73044:D0Z67_RS18115
uniprot id: A0A4P6TYH0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS28950
gene id: 73044:D0Z67_RS28950
uniprot id: A0A4P6U1Q0
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

73044:D0Z67 RS07315
gene id: 73044:D0Z67_RS07315
uniprot id: A0A4P6TS02
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS24090
gene id: 73044:D0Z67_RS24090
uniprot id: A0A4P6U1Y8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS24815
gene id: 73044:D0Z67_RS24815
uniprot id: A0A4P6U1X9
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

73044:D0Z67 RS17545
gene id: 73044:D0Z67_RS17545
uniprot id: A0A4P6TZ42
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

73044:D0Z67 RS13810
gene id: 73044:D0Z67_RS13810
uniprot id: A0A4P6TUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

73044:D0Z67 RS04290
gene id: 73044:D0Z67_RS04290
uniprot id: A0A4P6TQI9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS14990
gene id: 73044:D0Z67_RS14990
uniprot id: A0A4P6TY01
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

73044:D0Z67 RS00015
gene id: 73044:D0Z67_RS00015
uniprot id: A0A4P6TQE6
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

73044:D0Z67 RS03225
gene id: 73044:D0Z67_RS03225
uniprot id: A0A4P6U288
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

73044:D0Z67 RS09715
gene id: 73044:D0Z67_RS09715
uniprot id: A0A4P6TVE3
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

73044:D0Z67 RS17225
gene id: 73044:D0Z67_RS17225
uniprot id: A0A4V0ZZQ0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

73044:D0Z67 RS12590
gene id: 73044:D0Z67_RS12590
uniprot id: A0A4P6TUC4
names: Similarity
messages: Belongs to the citrate synthase family.

73044:D0Z67 RS17205
gene id: 73044:D0Z67_RS17205
uniprot id: A0A4P6TYD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

73044:D0Z67 RS20515
gene id: 73044:D0Z67_RS20515
uniprot id: A0A4P6TXR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS01240
gene id: 73044:D0Z67_RS01240
uniprot id: A0A4P6TPJ5
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

73044:D0Z67 RS16515
gene id: 73044:D0Z67_RS16515
uniprot id: A0A4P6TYS3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

73044:D0Z67 RS07075
gene id: 73044:D0Z67_RS07075
uniprot id: A0A4P6TRR0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS12690
gene id: 73044:D0Z67_RS12690
uniprot id: A0A4V0ZZH2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

73044:D0Z67 RS03440
gene id: 73044:D0Z67_RS03440
uniprot id: A0A4P6TVC7
names: Similarity
messages: Belongs to the IMPACT family.

73044:D0Z67 RS14605
gene id: 73044:D0Z67_RS14605
uniprot id: A0A4P6U094
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

73044:D0Z67 RS18340
gene id: 73044:D0Z67_RS18340
uniprot id: A0A4P6TWY8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.
messages: Cytoplasm

73044:D0Z67 RS26995
gene id: 73044:D0Z67_RS26995
uniprot id: A0A4P6U2W1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

73044:D0Z67 RS02935
gene id: 73044:D0Z67_RS02935
uniprot id: A0A4P6TQ99
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS12035
gene id: 73044:D0Z67_RS12035
uniprot id: A0A4P6TU46
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

73044:D0Z67 RS08235
gene id: 73044:D0Z67_RS08235
uniprot id: A0A4P6TUA4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS02865
gene id: 73044:D0Z67_RS02865
uniprot id: A0A4P6TV39
names: Similarity
messages: Belongs to the asparagine synthetase family.

73044:D0Z67 RS06615
gene id: 73044:D0Z67_RS06615
uniprot id: A0A4P6TTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

73044:D0Z67 RS17110
gene id: 73044:D0Z67_RS17110
uniprot id: A0A4P6TW49
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

73044:D0Z67 RS04550
gene id: 73044:D0Z67_RS04550
uniprot id: A0A4P6TSP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

73044:D0Z67 RS17030
gene id: 73044:D0Z67_RS17030
uniprot id: A0A4P6TYA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

73044:D0Z67 RS10710
gene id: 73044:D0Z67_RS10710
uniprot id: A0A4P6TWC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

73044:D0Z67 RS25240
gene id: 73044:D0Z67_RS25240
uniprot id: A0A4P6U245
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

73044:D0Z67 RS26575
gene id: 73044:D0Z67_RS26575
uniprot id: A0A4P6U2P3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

73044:D0Z67 RS10105
gene id: 73044:D0Z67_RS10105
uniprot id: A0A4P6TW46
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS15555
gene id: 73044:D0Z67_RS15555
uniprot id: A0A4P6TVF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS09630
gene id: 73044:D0Z67_RS09630
uniprot id: A0A4P6TY42
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS28365
gene id: 73044:D0Z67_RS28365
uniprot id: A0A4P6U1H6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS07680
gene id: 73044:D0Z67_RS07680
uniprot id: A0A4P6TU14
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07545
gene id: 73044:D0Z67_RS07545
uniprot id: A0A4P6TSD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS13840
gene id: 73044:D0Z67_RS13840
uniprot id: A0A4P6TXM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

73044:D0Z67 RS05190
gene id: 73044:D0Z67_RS05190
uniprot id: A0A4P6TTA0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

73044:D0Z67 RS19700
gene id: 73044:D0Z67_RS19700
uniprot id: A0A4P6TZ80
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

73044:D0Z67 RS21385
gene id: 73044:D0Z67_RS21385
uniprot id: A0A4P6TYK7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS16320
gene id: 73044:D0Z67_RS16320
uniprot id: A0A4P6TW09
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

73044:D0Z67 RS07795
gene id: 73044:D0Z67_RS07795
uniprot id: A0A4P6TS60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

73044:D0Z67 RS12655
gene id: 73044:D0Z67_RS12655
uniprot id: A0A4P6TUP7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

73044:D0Z67 RS06000
gene id: 73044:D0Z67_RS06000
uniprot id: A0A4P6TTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS10215
gene id: 73044:D0Z67_RS10215
uniprot id: A0A4P6U3X1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

73044:D0Z67 RS14460
gene id: 73044:D0Z67_RS14460
uniprot id: A0A4P6TX34
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

73044:D0Z67 RS23985
gene id: 73044:D0Z67_RS23985
uniprot id: A0A4P6U236
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

73044:D0Z67 RS14470
gene id: 73044:D0Z67_RS14470
uniprot id: A0A4P6TXQ1
names: Similarity
messages: Belongs to the FemABX family.

73044:D0Z67 RS17520
gene id: 73044:D0Z67_RS17520
uniprot id: A0A4P6TWK5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

73044:D0Z67 RS05080
gene id: 73044:D0Z67_RS05080
uniprot id: A0A4P6TT81
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

73044:D0Z67 RS25335
gene id: 73044:D0Z67_RS25335
uniprot id: A0A4P6U081
names: Similarity
messages: Belongs to the UPF0098 family.

73044:D0Z67 RS06395
gene id: 73044:D0Z67_RS06395
uniprot id: A0A4P6TTU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

73044:D0Z67 RS20900
gene id: 73044:D0Z67_RS20900
uniprot id: A0A4P6U0M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

73044:D0Z67 RS26980
gene id: 73044:D0Z67_RS26980
uniprot id: A0A4P6U0W0
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

73044:D0Z67 RS10440
gene id: 73044:D0Z67_RS10440
uniprot id: A0A4P6TV28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS09080
gene id: 73044:D0Z67_RS09080
uniprot id: A0A4P6TT19
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS26465
gene id: 73044:D0Z67_RS26465
uniprot id: A0A4P6U2E6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS05200
gene id: 73044:D0Z67_RS05200
uniprot id: A0A4V0ZZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

73044:D0Z67 RS16215
gene id: 73044:D0Z67_RS16215
uniprot id: A0A4P6TW91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS04295
gene id: 73044:D0Z67_RS04295
uniprot id: A0A4V0ZZ25
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

73044:D0Z67 RS21050
gene id: 73044:D0Z67_RS21050
uniprot id: A0A4P6U044
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS16050
gene id: 73044:D0Z67_RS16050
uniprot id: A0A4P6TYL1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS20690
gene id: 73044:D0Z67_RS20690
uniprot id: A0A4P6TZZ4
names: Cofactor
messages: Binds 1 FAD per subunit.

73044:D0Z67 RS02495
gene id: 73044:D0Z67_RS02495
uniprot id: A0A4P6TSU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS19435
gene id: 73044:D0Z67_RS19435
uniprot id: A0A4P6U005
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS22300
gene id: 73044:D0Z67_RS22300
uniprot id: A0A4P6TYG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS27280
gene id: 73044:D0Z67_RS27280
uniprot id: A0A4P6U3B2
names: Subcellular Location Annotation
messages: Secreted

73044:D0Z67 RS15875
gene id: 73044:D0Z67_RS15875
uniprot id: A0A4P6TYI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

73044:D0Z67 RS28165
gene id: 73044:D0Z67_RS28165
uniprot id: A0A4P6U3E2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS18690
gene id: 73044:D0Z67_RS18690
uniprot id: A0A4P6TZN3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS11935
gene id: 73044:D0Z67_RS11935
uniprot id: A0A4P6TW17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS08670
gene id: 73044:D0Z67_RS08670
uniprot id: A0A4P6TVJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS11265
gene id: 73044:D0Z67_RS11265
uniprot id: A0A4P6TTP6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

73044:D0Z67 RS01755
gene id: 73044:D0Z67_RS01755
uniprot id: A0A4P6TPF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS21810
gene id: 73044:D0Z67_RS21810
uniprot id: A0A4P6U0F7
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS14145
gene id: 73044:D0Z67_RS14145
uniprot id: A0A4V0ZZJ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS08165
gene id: 73044:D0Z67_RS08165
uniprot id: A0A4P6TVC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

73044:D0Z67 RS05130
gene id: 73044:D0Z67_RS05130
uniprot id: A0A4P6TSY2
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

73044:D0Z67 RS10970
gene id: 73044:D0Z67_RS10970
uniprot id: A0A4P6TYP2
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

73044:D0Z67 RS15855
gene id: 73044:D0Z67_RS15855
uniprot id: A0A4P6TXH1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS20250
gene id: 73044:D0Z67_RS20250
uniprot id: A0A4P6U4N4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS18525
gene id: 73044:D0Z67_RS18525
uniprot id: A0A4P6TZL5
names: Similarity
messages: Belongs to the DSD1 family.

73044:D0Z67 RS22515
gene id: 73044:D0Z67_RS22515
uniprot id: A0A4P6TYK5
names: Similarity
messages: Belongs to the thioesterase family.

73044:D0Z67 RS05370
gene id: 73044:D0Z67_RS05370
uniprot id: A0A4P6TT18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS04575
gene id: 73044:D0Z67_RS04575
uniprot id: A0A4P6TSD7
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

73044:D0Z67 RS03240
gene id: 73044:D0Z67_RS03240
uniprot id: A0A4P6TT58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

73044:D0Z67 RS18160
gene id: 73044:D0Z67_RS18160
uniprot id: A0A4V0ZZR7
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

73044:D0Z67 RS08770
gene id: 73044:D0Z67_RS08770
uniprot id: A0A4P6TSM0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS01300
gene id: 73044:D0Z67_RS01300
uniprot id: A0A4P6TSC6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08785
gene id: 73044:D0Z67_RS08785
uniprot id: A0A4P6TXP6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

73044:D0Z67 RS03085
gene id: 73044:D0Z67_RS03085
uniprot id: A0A4P6TS82
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS21635
gene id: 73044:D0Z67_RS21635
uniprot id: A0A4P6U017
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

73044:D0Z67 RS10375
gene id: 73044:D0Z67_RS10375
uniprot id: A0A4P6TYF6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS16205
gene id: 73044:D0Z67_RS16205
uniprot id: A0A4P6TVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

73044:D0Z67 RS04200
gene id: 73044:D0Z67_RS04200
uniprot id: A0A4P6TQI7
names: Similarity
messages: Belongs to the barstar family.

73044:D0Z67 RS07020
gene id: 73044:D0Z67_RS07020
uniprot id: A0A4P6U2D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

73044:D0Z67 RS06530
gene id: 73044:D0Z67_RS06530
uniprot id: A0A4P6TRV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

73044:D0Z67 RS08620
gene id: 73044:D0Z67_RS08620
uniprot id: A0A4P6TUH7
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

73044:D0Z67 RS06415
gene id: 73044:D0Z67_RS06415
uniprot id: A0A4P6TWM5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

73044:D0Z67 RS07560
gene id: 73044:D0Z67_RS07560
uniprot id: A0A4P6TTZ5
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

73044:D0Z67 RS10080
gene id: 73044:D0Z67_RS10080
uniprot id: A0A4V0ZZC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS19570
gene id: 73044:D0Z67_RS19570
uniprot id: A0A4P6U016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS07810
gene id: 73044:D0Z67_RS07810
uniprot id: A0A4P6TTU9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09550
gene id: 73044:D0Z67_RS09550
uniprot id: A0A4P6TUX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

73044:D0Z67 RS27530
gene id: 73044:D0Z67_RS27530
uniprot id: A0A4P6U1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS13145
gene id: 73044:D0Z67_RS13145
uniprot id: A0A4P6TWJ0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

73044:D0Z67 RS15345
gene id: 73044:D0Z67_RS15345
uniprot id: A0A4P6TXA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

73044:D0Z67 RS07420
gene id: 73044:D0Z67_RS07420
uniprot id: A0A4P6TX32
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09355
gene id: 73044:D0Z67_RS09355
uniprot id: A0A4P6TUJ7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

73044:D0Z67 RS09555
gene id: 73044:D0Z67_RS09555
uniprot id: A0A4P6TUX7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

73044:D0Z67 RS04235
gene id: 73044:D0Z67_RS04235
uniprot id: A0A4V0ZZ24
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS23005
gene id: 73044:D0Z67_RS23005
uniprot id: A0A4P6U428
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

73044:D0Z67 RS04385
gene id: 73044:D0Z67_RS04385
uniprot id: A0A4P6TSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

73044:D0Z67 RS17855
gene id: 73044:D0Z67_RS17855
uniprot id: A0A4P6TX02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS27385
gene id: 73044:D0Z67_RS27385
uniprot id: A0A4P6U2Y0
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS00285
gene id: 73044:D0Z67_RS00285
uniprot id: A0A4P6TU10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

73044:D0Z67 RS25765
gene id: 73044:D0Z67_RS25765
uniprot id: A0A4P6U0Q4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

73044:D0Z67 RS01565
gene id: 73044:D0Z67_RS01565
uniprot id: A0A4P6TRA1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS11920
gene id: 73044:D0Z67_RS11920
uniprot id: A0A4P6TU28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

73044:D0Z67 RS00905
gene id: 73044:D0Z67_RS00905
uniprot id: A0A4V0ZYW7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

73044:D0Z67 RS14650
gene id: 73044:D0Z67_RS14650
uniprot id: A0A4P6TV17
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

73044:D0Z67 RS22760
gene id: 73044:D0Z67_RS22760
uniprot id: A0A4V0ZZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

73044:D0Z67 RS00645
gene id: 73044:D0Z67_RS00645
uniprot id: A0A4P6TS29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

73044:D0Z67 RS26365
gene id: 73044:D0Z67_RS26365
uniprot id: A0A4P6U059
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

73044:D0Z67 RS16755
gene id: 73044:D0Z67_RS16755
uniprot id: A0A4P6TYV1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

73044:D0Z67 RS03120
gene id: 73044:D0Z67_RS03120
uniprot id: A0A4P6TT40
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

73044:D0Z67 RS09160
gene id: 73044:D0Z67_RS09160
uniprot id: A0A4P6TSS8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

73044:D0Z67 RS06265
gene id: 73044:D0Z67_RS06265
uniprot id: A0A4P6TRS7
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

73044:D0Z67 RS09620
gene id: 73044:D0Z67_RS09620
uniprot id: A0A4V0ZZB9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

73044:D0Z67 RS06455
gene id: 73044:D0Z67_RS06455
uniprot id: A0A4V0ZZ63
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS28310
gene id: 73044:D0Z67_RS28310
uniprot id: A0A4P6U6E5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

73044:D0Z67 RS13270
gene id: 73044:D0Z67_RS13270
uniprot id: A0A4P6TWL1
names: Similarity
messages: Belongs to the peptidase C40 family.

73044:D0Z67 RS17835
gene id: 73044:D0Z67_RS17835
uniprot id: A0A4V0ZZR1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS17540
gene id: 73044:D0Z67_RS17540
uniprot id: A0A4P6TYJ1
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

73044:D0Z67 RS19625
gene id: 73044:D0Z67_RS19625
uniprot id: A0A4P6U027
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

73044:D0Z67 RS11945
gene id: 73044:D0Z67_RS11945
uniprot id: A0A4P6TWE4
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

73044:D0Z67 RS06555
gene id: 73044:D0Z67_RS06555
uniprot id: A0A4P6TRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

73044:D0Z67 RS08025
gene id: 73044:D0Z67_RS08025
uniprot id: A0A4P6TSA2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS09195
gene id: 73044:D0Z67_RS09195
uniprot id: A0A4P6TVS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

73044:D0Z67 RS23175
gene id: 73044:D0Z67_RS23175
uniprot id: A0A4P6TZG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

73044:D0Z67 RS17090
gene id: 73044:D0Z67_RS17090
uniprot id: A0A4P6TZ11
names: Similarity
messages: Belongs to the UPF0336 family.

73044:D0Z67 RS19970
gene id: 73044:D0Z67_RS19970
uniprot id: A0A4V0ZZU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS24530
gene id: 73044:D0Z67_RS24530
uniprot id: A0A4P6U267
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09920
gene id: 73044:D0Z67_RS09920
uniprot id: A0A4P6TY86
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS18725
gene id: 73044:D0Z67_RS18725
uniprot id: A0A4V1A0D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

73044:D0Z67 RS28055
gene id: 73044:D0Z67_RS28055
uniprot id: A0A4P6U3C6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

73044:D0Z67 RS07515
gene id: 73044:D0Z67_RS07515
uniprot id: A0A4P6TUD5
names: Similarity
messages: Belongs to the peptidase C40 family.

73044:D0Z67 RS16690
gene id: 73044:D0Z67_RS16690
uniprot id: A0A4P6U195
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS17860
gene id: 73044:D0Z67_RS17860
uniprot id: A0A4P6U4U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS07735
gene id: 73044:D0Z67_RS07735
uniprot id: A0A4P6TU23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

73044:D0Z67 RS01995
gene id: 73044:D0Z67_RS01995
uniprot id: A0A4P6TUQ5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07975
gene id: 73044:D0Z67_RS07975
uniprot id: A0A4V0ZZ90
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

73044:D0Z67 RS10250
gene id: 73044:D0Z67_RS10250
uniprot id: A0A4P6TYD9
names: Similarity
messages: Belongs to the IucA/IucC family.

73044:D0Z67 RS26060
gene id: 73044:D0Z67_RS26060
uniprot id: A0A4P6U284
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

73044:D0Z67 RS02270
gene id: 73044:D0Z67_RS02270
uniprot id: A0A4P6TRL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

73044:D0Z67 RS16820
gene id: 73044:D0Z67_RS16820
uniprot id: A0A4P6TYR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS22195
gene id: 73044:D0Z67_RS22195
uniprot id: A0A4V0ZZY7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS05605
gene id: 73044:D0Z67_RS05605
uniprot id: A0A4P6TT35
names: Similarity
messages: Belongs to the peptidase S1 family.

73044:D0Z67 RS23305
gene id: 73044:D0Z67_RS23305
uniprot id: A0A4P6U118
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

73044:D0Z67 RS22395
gene id: 73044:D0Z67_RS22395
uniprot id: A0A4P6U0P3
names: Similarity
messages: Belongs to the thioesterase family.

73044:D0Z67 RS07205
gene id: 73044:D0Z67_RS07205
uniprot id: A0A4P6TWZ5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

73044:D0Z67 RS16740
gene id: 73044:D0Z67_RS16740
uniprot id: A0A4P6U1A7
names: Similarity
messages: Belongs to the peptidase A24 family.

73044:D0Z67 RS10130
gene id: 73044:D0Z67_RS10130
uniprot id: A0A4V0ZZC8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS19870
gene id: 73044:D0Z67_RS19870
uniprot id: A0A4P6U2N4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS17005
gene id: 73044:D0Z67_RS17005
uniprot id: A0A4P6U1F7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS10190
gene id: 73044:D0Z67_RS10190
uniprot id: A0A4P6TYD0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS16110
gene id: 73044:D0Z67_RS16110
uniprot id: A0A4P6TXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

73044:D0Z67 RS02690
gene id: 73044:D0Z67_RS02690
uniprot id: A0A4P6TV11
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

73044:D0Z67 RS07105
gene id: 73044:D0Z67_RS07105
uniprot id: A0A4P6TS53
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS23295
gene id: 73044:D0Z67_RS23295
uniprot id: A0A4P6U1L0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

73044:D0Z67 RS19405
gene id: 73044:D0Z67_RS19405
uniprot id: A0A4P6U2H2
names: Similarity
messages: Belongs to the peptidase S16 family.

73044:D0Z67 RS16150
gene id: 73044:D0Z67_RS16150
uniprot id: A0A4P6TVX9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS10420
gene id: 73044:D0Z67_RS10420
uniprot id: A0A4P6TTC8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

73044:D0Z67 RS04120
gene id: 73044:D0Z67_RS04120
uniprot id: A0A4P6TSG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

73044:D0Z67 RS08360
gene id: 73044:D0Z67_RS08360
uniprot id: A0A4V0ZZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

73044:D0Z67 RS25995
gene id: 73044:D0Z67_RS25995
uniprot id: A0A4P6U0T5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

73044:D0Z67 RS17465
gene id: 73044:D0Z67_RS17465
uniprot id: A0A4P6TWU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS04895
gene id: 73044:D0Z67_RS04895
uniprot id: A0A4P6TSU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

73044:D0Z67 RS26735
gene id: 73044:D0Z67_RS26735
uniprot id: A0A4P6U334
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS10960
gene id: 73044:D0Z67_RS10960
uniprot id: A0A4V0ZZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS07065
gene id: 73044:D0Z67_RS07065
uniprot id: A0A4P6TTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

73044:D0Z67 RS20460
gene id: 73044:D0Z67_RS20460
uniprot id: A0A4P6U0G3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

73044:D0Z67 RS08840
gene id: 73044:D0Z67_RS08840
uniprot id: A0A4P6TXQ5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

73044:D0Z67 RS03995
gene id: 73044:D0Z67_RS03995
uniprot id: A0A4P6TQF2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS28385
gene id: 73044:D0Z67_RS28385
uniprot id: A0A4P6U392
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

73044:D0Z67 RS05695
gene id: 73044:D0Z67_RS05695
uniprot id: A0A4P6TRJ4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

73044:D0Z67 RS07220
gene id: 73044:D0Z67_RS07220
uniprot id: A0A4P6TUX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

73044:D0Z67 RS07095
gene id: 73044:D0Z67_RS07095
uniprot id: A0A4P6TWY3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

73044:D0Z67 RS07530
gene id: 73044:D0Z67_RS07530
uniprot id: A0A4P6TTQ5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS18055
gene id: 73044:D0Z67_RS18055
uniprot id: A0A4V0ZZR5
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

73044:D0Z67 RS28665
gene id: 73044:D0Z67_RS28665
uniprot id: A0A4P6U6K1
names: Similarity
messages: Belongs to the HypE family.

73044:D0Z67 RS25610
gene id: 73044:D0Z67_RS25610
uniprot id: A0A4P6U207
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS26130
gene id: 73044:D0Z67_RS26130
uniprot id: A0A4P6U2H3
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

73044:D0Z67 RS00750
gene id: 73044:D0Z67_RS00750
uniprot id: A0A4P6TU77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS05860
gene id: 73044:D0Z67_RS05860
uniprot id: A0A4V0ZZ52
names: Similarity
messages: Belongs to the UPF0098 family.

73044:D0Z67 RS24760
gene id: 73044:D0Z67_RS24760
uniprot id: A0A4P6U299
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

73044:D0Z67 RS08940
gene id: 73044:D0Z67_RS08940
uniprot id: A0A4V0ZZA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

73044:D0Z67 RS09300
gene id: 73044:D0Z67_RS09300
uniprot id: A0A4P6TXY7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

73044:D0Z67 RS17260
gene id: 73044:D0Z67_RS17260
uniprot id: A0A4P6TYE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

73044:D0Z67 RS15980
gene id: 73044:D0Z67_RS15980
uniprot id: A0A4P6TW50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

73044:D0Z67 RS14450
gene id: 73044:D0Z67_RS14450
uniprot id: A0A4P6TVG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

73044:D0Z67 RS09040
gene id: 73044:D0Z67_RS09040
uniprot id: A0A4P6TUP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

73044:D0Z67 RS15925
gene id: 73044:D0Z67_RS15925
uniprot id: A0A4P6TYJ5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08130
gene id: 73044:D0Z67_RS08130
uniprot id: A0A4P6TUM6
names: Similarity
messages: Belongs to the EfeM/EfeO family.

73044:D0Z67 RS07245
gene id: 73044:D0Z67_RS07245
uniprot id: A0A4P6TRV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS02385
gene id: 73044:D0Z67_RS02385
uniprot id: A0A4P6TRN2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS27610
gene id: 73044:D0Z67_RS27610
uniprot id: A0A4P6U0N8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS10620
gene id: 73044:D0Z67_RS10620
uniprot id: A0A4P6TTF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

73044:D0Z67 RS16680
gene id: 73044:D0Z67_RS16680
uniprot id: A0A4V0ZZP0
names: Similarity
messages: Belongs to the UbiD family.

73044:D0Z67 RS23875
gene id: 73044:D0Z67_RS23875
uniprot id: A0A4P6U1I7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS08775
gene id: 73044:D0Z67_RS08775
uniprot id: A0A4V0ZZA4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS13525
gene id: 73044:D0Z67_RS13525
uniprot id: A0A4P6TUS4
names: Similarity
messages: Belongs to the PstS family.

73044:D0Z67 RS02545
gene id: 73044:D0Z67_RS02545
uniprot id: A0A4P6TQ38
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

73044:D0Z67 RS08805
gene id: 73044:D0Z67_RS08805
uniprot id: A0A4P6TUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

73044:D0Z67 RS00520
gene id: 73044:D0Z67_RS00520
uniprot id: A0A4P6TU43
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

73044:D0Z67 RS10110
gene id: 73044:D0Z67_RS10110
uniprot id: A0A4P6TV67
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

73044:D0Z67 RS18760
gene id: 73044:D0Z67_RS18760
uniprot id: A0A4P6TZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

73044:D0Z67 RS06440
gene id: 73044:D0Z67_RS06440
uniprot id: A0A4P6TTH8
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

73044:D0Z67 RS09310
gene id: 73044:D0Z67_RS09310
uniprot id: A0A4P6TT51
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS03230
gene id: 73044:D0Z67_RS03230
uniprot id: A0A4P6TQ42
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

73044:D0Z67 RS16530
gene id: 73044:D0Z67_RS16530
uniprot id: A0A4P6TYM4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS06975
gene id: 73044:D0Z67_RS06975
uniprot id: A0A4P6TWW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

73044:D0Z67 RS24295
gene id: 73044:D0Z67_RS24295
uniprot id: A0A4P6U167
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

73044:D0Z67 RS02785
gene id: 73044:D0Z67_RS02785
uniprot id: A0A4P6TRX0
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

73044:D0Z67 RS15105
gene id: 73044:D0Z67_RS15105
uniprot id: A0A4P6TV81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

73044:D0Z67 RS29225
gene id: 73044:D0Z67_RS29225
uniprot id: A0A4P6U556
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

73044:D0Z67 RS14815
gene id: 73044:D0Z67_RS14815
uniprot id: A0A4P6TX89
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

73044:D0Z67 RS27660
gene id: 73044:D0Z67_RS27660
uniprot id: A0A4P6U2Y4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

73044:D0Z67 RS20615
gene id: 73044:D0Z67_RS20615
uniprot id: A0A4P6U0H5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

73044:D0Z67 RS13240
gene id: 73044:D0Z67_RS13240
uniprot id: A0A4V0ZZI1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03150
gene id: 73044:D0Z67_RS03150
uniprot id: A0A4P6TRP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

73044:D0Z67 RS28720
gene id: 73044:D0Z67_RS28720
uniprot id: A0A4P6U6K8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS03525
gene id: 73044:D0Z67_RS03525
uniprot id: A0A4P6TTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS17220
gene id: 73044:D0Z67_RS17220
uniprot id: A0A4P6TW67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

73044:D0Z67 RS17530
gene id: 73044:D0Z67_RS17530
uniprot id: A0A4P6TZ68
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS17350
gene id: 73044:D0Z67_RS17350
uniprot id: A0A4P6TWI5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

73044:D0Z67 RS21600
gene id: 73044:D0Z67_RS21600
uniprot id: A0A4P6TYQ1
names: Similarity
messages: Belongs to the peptidase M16 family.

73044:D0Z67 RS03145
gene id: 73044:D0Z67_RS03145
uniprot id: A0A4V0ZZ05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

73044:D0Z67 RS28415
gene id: 73044:D0Z67_RS28415
uniprot id: A0A4P6U1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

73044:D0Z67 RS27525
gene id: 73044:D0Z67_RS27525
uniprot id: A0A4P6U144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS17340
gene id: 73044:D0Z67_RS17340
uniprot id: A0A4P6TY52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

73044:D0Z67 RS16425
gene id: 73044:D0Z67_RS16425
uniprot id: A0A4P6TYK9
names: Similarity
messages: Belongs to the histone deacetylase family.

73044:D0Z67 RS11105
gene id: 73044:D0Z67_RS11105
uniprot id: A0A4P6TTN8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

73044:D0Z67 RS12000
gene id: 73044:D0Z67_RS12000
uniprot id: A0A4P6TW11
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

73044:D0Z67 RS22795
gene id: 73044:D0Z67_RS22795
uniprot id: A0A4P6U0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

73044:D0Z67 RS20575
gene id: 73044:D0Z67_RS20575
uniprot id: A0A4P6U2L1
names: Similarity
messages: Belongs to the LOG family.

73044:D0Z67 RS10270
gene id: 73044:D0Z67_RS10270
uniprot id: A0A4P6TTK4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS25755
gene id: 73044:D0Z67_RS25755
uniprot id: A0A4P6U599
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

73044:D0Z67 RS02360
gene id: 73044:D0Z67_RS02360
uniprot id: A0A4P6TRC7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

73044:D0Z67 RS22855
gene id: 73044:D0Z67_RS22855
uniprot id: A0A4P6TZA6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS05120
gene id: 73044:D0Z67_RS05120
uniprot id: A0A4P6TU07
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

73044:D0Z67 RS24785
gene id: 73044:D0Z67_RS24785
uniprot id: A0A4V1A033
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS22670
gene id: 73044:D0Z67_RS22670
uniprot id: A0A4P6TYW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS06605
gene id: 73044:D0Z67_RS06605
uniprot id: A0A4P6TRI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

73044:D0Z67 RS03435
gene id: 73044:D0Z67_RS03435
uniprot id: A0A4P6TRV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

73044:D0Z67 RS04330
gene id: 73044:D0Z67_RS04330
uniprot id: A0A4P6TSK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS20670
gene id: 73044:D0Z67_RS20670
uniprot id: A0A4P6TY88
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

73044:D0Z67 RS03955
gene id: 73044:D0Z67_RS03955
uniprot id: A0A4P6U3P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

73044:D0Z67 RS21335
gene id: 73044:D0Z67_RS21335
uniprot id: A0A4P6U097
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS05795
gene id: 73044:D0Z67_RS05795
uniprot id: A0A4P6TRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

73044:D0Z67 RS05105
gene id: 73044:D0Z67_RS05105
uniprot id: A0A4P6TW40
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

73044:D0Z67 RS09045
gene id: 73044:D0Z67_RS09045
uniprot id: A0A4V1A0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS27220
gene id: 73044:D0Z67_RS27220
uniprot id: A0A4P6U1B3
names: Similarity
messages: Belongs to the threonine aldolase family.

73044:D0Z67 RS15635
gene id: 73044:D0Z67_RS15635
uniprot id: A0A4P6TVP3
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

73044:D0Z67 RS22030
gene id: 73044:D0Z67_RS22030
uniprot id: A0A4P6U3L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

73044:D0Z67 RS17155
gene id: 73044:D0Z67_RS17155
uniprot id: A0A4P6TYC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

73044:D0Z67 RS18855
gene id: 73044:D0Z67_RS18855
uniprot id: A0A4P6U2I4
names: Similarity
messages: Belongs to the serpin family.

73044:D0Z67 RS15095
gene id: 73044:D0Z67_RS15095
uniprot id: A0A4P6TXD2
names: Similarity
messages: Belongs to the pirin family.

73044:D0Z67 RS17355
gene id: 73044:D0Z67_RS17355
uniprot id: A0A4P6TWS3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS11195
gene id: 73044:D0Z67_RS11195
uniprot id: A0A4P6TVP4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

73044:D0Z67 RS23890
gene id: 73044:D0Z67_RS23890
uniprot id: A0A4P6TZ53
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

73044:D0Z67 RS28145
gene id: 73044:D0Z67_RS28145
uniprot id: A0A4P6U1D5
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

73044:D0Z67 RS16745
gene id: 73044:D0Z67_RS16745
uniprot id: A0A4P6TW76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

73044:D0Z67 RS01780
gene id: 73044:D0Z67_RS01780
uniprot id: A0A4P6TPS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

73044:D0Z67 RS06105
gene id: 73044:D0Z67_RS06105
uniprot id: A0A4P6TTD2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

73044:D0Z67 RS00035
gene id: 73044:D0Z67_RS00035
uniprot id: A0A4P6TRT0
names: Similarity
messages: Belongs to the peptidase S9C family.

73044:D0Z67 RS17720
gene id: 73044:D0Z67_RS17720
uniprot id: A0A4P6TZ67
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS07770
gene id: 73044:D0Z67_RS07770
uniprot id: A0A4P6TSG5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS23730
gene id: 73044:D0Z67_RS23730
uniprot id: A0A4V1A014
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS04170
gene id: 73044:D0Z67_RS04170
uniprot id: A0A4P6TSH5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

73044:D0Z67 RS16835
gene id: 73044:D0Z67_RS16835
uniprot id: A0A4P6TXX2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03100
gene id: 73044:D0Z67_RS03100
uniprot id: A0A4P6TRN4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

73044:D0Z67 RS25005
gene id: 73044:D0Z67_RS25005
uniprot id: A0A4P6U1R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

73044:D0Z67 RS12190
gene id: 73044:D0Z67_RS12190
uniprot id: A0A4P6TX05
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

73044:D0Z67 RS24475
gene id: 73044:D0Z67_RS24475
uniprot id: A0A4P6U054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS28940
gene id: 73044:D0Z67_RS28940
uniprot id: A0A4P6U3M0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS16385
gene id: 73044:D0Z67_RS16385
uniprot id: A0A4P6TY04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

73044:D0Z67 RS10600
gene id: 73044:D0Z67_RS10600
uniprot id: A0A4P6TVE5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

73044:D0Z67 RS12865
gene id: 73044:D0Z67_RS12865
uniprot id: A0A4P6TUB6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

73044:D0Z67 RS21730
gene id: 73044:D0Z67_RS21730
uniprot id: A0A4P6U3G9
names: Similarity
messages: Belongs to the FPG family.

73044:D0Z67 RS10840
gene id: 73044:D0Z67_RS10840
uniprot id: A0A4P6TVX6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

73044:D0Z67 RS26420
gene id: 73044:D0Z67_RS26420
uniprot id: A0A4P6U067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS20560
gene id: 73044:D0Z67_RS20560
uniprot id: A0A4P6TZX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS18270
gene id: 73044:D0Z67_RS18270
uniprot id: A0A4P6TWR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

73044:D0Z67 RS04990
gene id: 73044:D0Z67_RS04990
uniprot id: A0A4P6TQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

73044:D0Z67 RS09345
gene id: 73044:D0Z67_RS09345
uniprot id: A0A4P6TSV3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

73044:D0Z67 RS28255
gene id: 73044:D0Z67_RS28255
uniprot id: A0A4P6U6D6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

73044:D0Z67 RS04080
gene id: 73044:D0Z67_RS04080
uniprot id: A0A4P6U4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

73044:D0Z67 RS03135
gene id: 73044:D0Z67_RS03135
uniprot id: A0A4P6TS92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS11910
gene id: 73044:D0Z67_RS11910
uniprot id: A0A4P6TVR9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS11995
gene id: 73044:D0Z67_RS11995
uniprot id: A0A4P6TW23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

73044:D0Z67 RS03080
gene id: 73044:D0Z67_RS03080
uniprot id: A0A4P6TS08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS04460
gene id: 73044:D0Z67_RS04460
uniprot id: A0A4P6TSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

73044:D0Z67 RS25750
gene id: 73044:D0Z67_RS25750
uniprot id: A0A4P6U1Z3
names: Subunit
messages: Homodimer.

73044:D0Z67 RS21590
gene id: 73044:D0Z67_RS21590
uniprot id: A0A4P6U3F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

73044:D0Z67 RS02150
gene id: 73044:D0Z67_RS02150
uniprot id: A0A4P6TPY0
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

73044:D0Z67 RS16380
gene id: 73044:D0Z67_RS16380
uniprot id: A0A4P6TYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS00580
gene id: 73044:D0Z67_RS00580
uniprot id: A0A4P6TU52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS25155
gene id: 73044:D0Z67_RS25155
uniprot id: A0A4P6U057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS13505
gene id: 73044:D0Z67_RS13505
uniprot id: A0A4P6TUL3
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS11365
gene id: 73044:D0Z67_RS11365
uniprot id: A0A4P6TTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

73044:D0Z67 RS08120
gene id: 73044:D0Z67_RS08120
uniprot id: A0A4P6TU81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

73044:D0Z67 RS08040
gene id: 73044:D0Z67_RS08040
uniprot id: A0A4P6TTY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

73044:D0Z67 RS12065
gene id: 73044:D0Z67_RS12065
uniprot id: A0A4P6TU08
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

73044:D0Z67 RS14705
gene id: 73044:D0Z67_RS14705
uniprot id: A0A4P6TV23
names: Similarity
messages: Belongs to the UPF0749 family.

73044:D0Z67 RS28495
gene id: 73044:D0Z67_RS28495
uniprot id: A0A4P6U5J0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

73044:D0Z67 RS14415
gene id: 73044:D0Z67_RS14415
uniprot id: A0A4P6TXP3
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS14355
gene id: 73044:D0Z67_RS14355
uniprot id: A0A4P6TX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

73044:D0Z67 RS24595
gene id: 73044:D0Z67_RS24595
uniprot id: A0A4P6U1K3
names: Similarity
messages: Belongs to the YciI family.

73044:D0Z67 RS24835
gene id: 73044:D0Z67_RS24835
uniprot id: A0A4V1A034
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

73044:D0Z67 RS09495
gene id: 73044:D0Z67_RS09495
uniprot id: A0A4P6TUW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

73044:D0Z67 RS17290
gene id: 73044:D0Z67_RS17290
uniprot id: A0A4P6TY43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

73044:D0Z67 RS15340
gene id: 73044:D0Z67_RS15340
uniprot id: A0A4V0ZZL7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

73044:D0Z67 RS00360
gene id: 73044:D0Z67_RS00360
uniprot id: A0A4P6TQU2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

73044:D0Z67 RS04360
gene id: 73044:D0Z67_RS04360
uniprot id: A0A4P6TVR8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

73044:D0Z67 RS01590
gene id: 73044:D0Z67_RS01590
uniprot id: A0A4V0ZYX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

73044:D0Z67 RS05310
gene id: 73044:D0Z67_RS05310
uniprot id: A0A4P6TSZ4
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

73044:D0Z67 RS04760
gene id: 73044:D0Z67_RS04760
uniprot id: A0A4V0ZZ33
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

73044:D0Z67 RS02625
gene id: 73044:D0Z67_RS02625
uniprot id: A0A4P6TPU2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS21125
gene id: 73044:D0Z67_RS21125
uniprot id: A0A4V0ZZW9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

73044:D0Z67 RS08555
gene id: 73044:D0Z67_RS08555
uniprot id: A0A4P6TVI2
names: Similarity
messages: Belongs to the aldose epimerase family.

73044:D0Z67 RS20130
gene id: 73044:D0Z67_RS20130
uniprot id: A0A4V0ZZV2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS23640
gene id: 73044:D0Z67_RS23640
uniprot id: A0A4P6U4C3
names: Similarity
messages: Belongs to the allantoicase family.

73044:D0Z67 RS20925
gene id: 73044:D0Z67_RS20925
uniprot id: A0A4P6TY22
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

73044:D0Z67 RS14745
gene id: 73044:D0Z67_RS14745
uniprot id: A0A4P6TX78
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06590
gene id: 73044:D0Z67_RS06590
uniprot id: A0A4P6TTJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

73044:D0Z67 RS26415
gene id: 73044:D0Z67_RS26415
uniprot id: A0A4P6U349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS18185
gene id: 73044:D0Z67_RS18185
uniprot id: A0A4P6TZH4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS27340
gene id: 73044:D0Z67_RS27340
uniprot id: A0A4P6U2T0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

73044:D0Z67 RS12730
gene id: 73044:D0Z67_RS12730
uniprot id: A0A4P6TWB7
names: Subcellular Location Annotation
messages: Cell membrane

73044:D0Z67 RS03845
gene id: 73044:D0Z67_RS03845
uniprot id: A0A4P6TSC0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS16200
gene id: 73044:D0Z67_RS16200
uniprot id: A0A4P6U122
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

73044:D0Z67 RS14585
gene id: 73044:D0Z67_RS14585
uniprot id: A0A4V0ZZK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

73044:D0Z67 RS05150
gene id: 73044:D0Z67_RS05150
uniprot id: A0A4P6TSN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

73044:D0Z67 RS06120
gene id: 73044:D0Z67_RS06120
uniprot id: A0A4P6TTQ1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08180
gene id: 73044:D0Z67_RS08180
uniprot id: A0A4P6TU97
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS16975
gene id: 73044:D0Z67_RS16975
uniprot id: A0A4P6TYA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS17775
gene id: 73044:D0Z67_RS17775
uniprot id: A0A4P6TZ74
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS27335
gene id: 73044:D0Z67_RS27335
uniprot id: A0A4P6U316
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS00700
gene id: 73044:D0Z67_RS00700
uniprot id: A0A4P6TPB7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS21140
gene id: 73044:D0Z67_RS21140
uniprot id: A0A4P6TY57
names: Similarity
messages: Belongs to the UPF0102 family.

73044:D0Z67 RS28905
gene id: 73044:D0Z67_RS28905
uniprot id: A0A4P6U210
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03380
gene id: 73044:D0Z67_RS03380
uniprot id: A0A4P6U3N3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

73044:D0Z67 RS12770
gene id: 73044:D0Z67_RS12770
uniprot id: A0A4P6TUR3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

73044:D0Z67 RS04255
gene id: 73044:D0Z67_RS04255
uniprot id: A0A4P6TQK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

73044:D0Z67 RS26300
gene id: 73044:D0Z67_RS26300
uniprot id: A0A4P6U2C1
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

73044:D0Z67 RS18130
gene id: 73044:D0Z67_RS18130
uniprot id: A0A4P6TX45
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

73044:D0Z67 RS13815
gene id: 73044:D0Z67_RS13815
uniprot id: A0A4V0ZZJ1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

73044:D0Z67 RS03285
gene id: 73044:D0Z67_RS03285
uniprot id: A0A4P6TQE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS15080
gene id: 73044:D0Z67_RS15080
uniprot id: A0A4P6TVQ6
names: Similarity
messages: Belongs to the peptidase M18 family.

73044:D0Z67 RS20020
gene id: 73044:D0Z67_RS20020
uniprot id: A0A4P6U096
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

73044:D0Z67 RS16845
gene id: 73044:D0Z67_RS16845
uniprot id: A0A4P6U1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS26505
gene id: 73044:D0Z67_RS26505
uniprot id: A0A4P6U109
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

73044:D0Z67 RS21065
gene id: 73044:D0Z67_RS21065
uniprot id: A0A4V0ZZW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

73044:D0Z67 RS20395
gene id: 73044:D0Z67_RS20395
uniprot id: A0A4P6TZV1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09030
gene id: 73044:D0Z67_RS09030
uniprot id: A0A4P6TVP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

73044:D0Z67 RS20790
gene id: 73044:D0Z67_RS20790
uniprot id: A0A4P6TY06
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

73044:D0Z67 RS24425
gene id: 73044:D0Z67_RS24425
uniprot id: A0A4P6U1S3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

73044:D0Z67 RS21175
gene id: 73044:D0Z67_RS21175
uniprot id: A0A4P6TY03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

73044:D0Z67 RS17285
gene id: 73044:D0Z67_RS17285
uniprot id: A0A4V0ZZQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

73044:D0Z67 RS06575
gene id: 73044:D0Z67_RS06575
uniprot id: A0A4P6TRN7
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

73044:D0Z67 RS15640
gene id: 73044:D0Z67_RS15640
uniprot id: A0A4P6TVZ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS07070
gene id: 73044:D0Z67_RS07070
uniprot id: A0A4P6TU60
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

73044:D0Z67 RS16350
gene id: 73044:D0Z67_RS16350
uniprot id: A0A4P6TVT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS05870
gene id: 73044:D0Z67_RS05870
uniprot id: A0A4P6TWG4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

73044:D0Z67 RS10090
gene id: 73044:D0Z67_RS10090
uniprot id: A0A4P6TYB2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

73044:D0Z67 RS06630
gene id: 73044:D0Z67_RS06630
uniprot id: A0A4P6TRY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

73044:D0Z67 RS09730
gene id: 73044:D0Z67_RS09730
uniprot id: A0A4P6TUR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

73044:D0Z67 RS20770
gene id: 73044:D0Z67_RS20770
uniprot id: A0A4V0ZZW3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

73044:D0Z67 RS08515
gene id: 73044:D0Z67_RS08515
uniprot id: A0A4P6TUF8
names: Similarity
messages: Belongs to the pirin family.

73044:D0Z67 RS00525
gene id: 73044:D0Z67_RS00525
uniprot id: A0A4P6TNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

73044:D0Z67 RS26425
gene id: 73044:D0Z67_RS26425
uniprot id: A0A4V1A061
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

73044:D0Z67 RS16065
gene id: 73044:D0Z67_RS16065
uniprot id: A0A4P6TYG3
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04310
gene id: 73044:D0Z67_RS04310
uniprot id: A0A4P6TQL0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

73044:D0Z67 RS30250
gene id: 73044:D0Z67_RS30250
uniprot id: A0A4P6U291
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03235
gene id: 73044:D0Z67_RS03235
uniprot id: A0A4P6TQD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

73044:D0Z67 RS09440
gene id: 73044:D0Z67_RS09440
uniprot id: A0A4P6TUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

73044:D0Z67 RS13025
gene id: 73044:D0Z67_RS13025
uniprot id: A0A4P6TWF0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS21605
gene id: 73044:D0Z67_RS21605
uniprot id: A0A4P6U0X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

73044:D0Z67 RS23050
gene id: 73044:D0Z67_RS23050
uniprot id: A0A4P6U0P4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

73044:D0Z67 RS11055
gene id: 73044:D0Z67_RS11055
uniprot id: A0A4P6TWH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

73044:D0Z67 RS17740
gene id: 73044:D0Z67_RS17740
uniprot id: A0A4P6TYB3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

73044:D0Z67 RS12100
gene id: 73044:D0Z67_RS12100
uniprot id: A0A4P6TUG6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

73044:D0Z67 RS26165
gene id: 73044:D0Z67_RS26165
uniprot id: A0A4P6U0L2
names: Similarity
messages: Belongs to the FPG family.

73044:D0Z67 RS12955
gene id: 73044:D0Z67_RS12955
uniprot id: A0A4P6TXA4
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

73044:D0Z67 RS27790
gene id: 73044:D0Z67_RS27790
uniprot id: A0A4P6U343
names: Similarity
messages: Belongs to the peptidase S1 family.

73044:D0Z67 RS25645
gene id: 73044:D0Z67_RS25645
uniprot id: A0A4P6U0C6
names: Similarity
messages: Belongs to the HIBADH-related family.

73044:D0Z67 RS18030
gene id: 73044:D0Z67_RS18030
uniprot id: A0A4P6TYR5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS23150
gene id: 73044:D0Z67_RS23150
uniprot id: A0A4P6TYU1
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.

73044:D0Z67 RS20445
gene id: 73044:D0Z67_RS20445
uniprot id: A0A4P6U0F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

73044:D0Z67 RS23960
gene id: 73044:D0Z67_RS23960
uniprot id: A0A4P6TZG9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS05110
gene id: 73044:D0Z67_RS05110
uniprot id: A0A4P6TR01
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

73044:D0Z67 RS19975
gene id: 73044:D0Z67_RS19975
uniprot id: A0A4P6U7H7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS19475
gene id: 73044:D0Z67_RS19475
uniprot id: A0A4P6TXG1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

73044:D0Z67 RS21360
gene id: 73044:D0Z67_RS21360
uniprot id: A0A4P6TY27
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS16815
gene id: 73044:D0Z67_RS16815
uniprot id: A0A4P6TY58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

73044:D0Z67 RS06810
gene id: 73044:D0Z67_RS06810
uniprot id: A0A4P6TUR9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

73044:D0Z67 RS24370
gene id: 73044:D0Z67_RS24370
uniprot id: A0A4P6U239
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

73044:D0Z67 RS04870
gene id: 73044:D0Z67_RS04870
uniprot id: A0A4P6TW02
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

73044:D0Z67 RS23230
gene id: 73044:D0Z67_RS23230
uniprot id: A0A4P6TZG7
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

73044:D0Z67 RS09200
gene id: 73044:D0Z67_RS09200
uniprot id: A0A4P6TUR2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

73044:D0Z67 RS04720
gene id: 73044:D0Z67_RS04720
uniprot id: A0A4P6TR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

73044:D0Z67 RS18585
gene id: 73044:D0Z67_RS18585
uniprot id: A0A4P6TZ17
names: Similarity
messages: Belongs to the GSP E family.

73044:D0Z67 RS14625
gene id: 73044:D0Z67_RS14625
uniprot id: A0A4P6TX58
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

73044:D0Z67 RS18685
gene id: 73044:D0Z67_RS18685
uniprot id: A0A4P6TXC9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09430
gene id: 73044:D0Z67_RS09430
uniprot id: A0A4P6TT70
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS25125
gene id: 73044:D0Z67_RS25125
uniprot id: A0A4P6U1S9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS10075
gene id: 73044:D0Z67_RS10075
uniprot id: A0A4P6TT77
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09350
gene id: 73044:D0Z67_RS09350
uniprot id: A0A4V0ZZB4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

73044:D0Z67 RS07990
gene id: 73044:D0Z67_RS07990
uniprot id: A0A4P6TXB8
names: Similarity
messages: Belongs to the glutamine synthetase family.

73044:D0Z67 RS18105
gene id: 73044:D0Z67_RS18105
uniprot id: A0A4P6TWN6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

73044:D0Z67 RS04015
gene id: 73044:D0Z67_RS04015
uniprot id: A0A4P6TSF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

73044:D0Z67 RS15350
gene id: 73044:D0Z67_RS15350
uniprot id: A0A4P6U0L5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

73044:D0Z67 RS06205
gene id: 73044:D0Z67_RS06205
uniprot id: A0A4P6TWJ3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

73044:D0Z67 RS18330
gene id: 73044:D0Z67_RS18330
uniprot id: A0A4P6TYK4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

73044:D0Z67 RS21490
gene id: 73044:D0Z67_RS21490
uniprot id: A0A4P6TYB0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

73044:D0Z67 RS17185
gene id: 73044:D0Z67_RS17185
uniprot id: A0A4P6U1H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

73044:D0Z67 RS02465
gene id: 73044:D0Z67_RS02465
uniprot id: A0A4P6U3X4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS21855
gene id: 73044:D0Z67_RS21855
uniprot id: A0A4P6U104
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

73044:D0Z67 RS02630
gene id: 73044:D0Z67_RS02630
uniprot id: A0A4V0ZYZ6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

73044:D0Z67 RS24745
gene id: 73044:D0Z67_RS24745
uniprot id: A0A4P6U4U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

73044:D0Z67 RS11220
gene id: 73044:D0Z67_RS11220
uniprot id: A0A4V0ZZE6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

73044:D0Z67 RS28395
gene id: 73044:D0Z67_RS28395
uniprot id: A0A4P6U169
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

73044:D0Z67 RS08535
gene id: 73044:D0Z67_RS08535
uniprot id: A0A4P6TU65
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

73044:D0Z67 RS16650
gene id: 73044:D0Z67_RS16650
uniprot id: A0A4P6TWF2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS21540
gene id: 73044:D0Z67_RS21540
uniprot id: A0A4P6TYB9
names: Similarity
messages: Belongs to the WXG100 family.

73044:D0Z67 RS11555
gene id: 73044:D0Z67_RS11555
uniprot id: A0A4P6TTW3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

73044:D0Z67 RS20185
gene id: 73044:D0Z67_RS20185
uniprot id: A0A4V0ZZV3
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

73044:D0Z67 RS15520
gene id: 73044:D0Z67_RS15520
uniprot id: A0A4P6TVM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

73044:D0Z67 RS04440
gene id: 73044:D0Z67_RS04440
uniprot id: A0A4P6TSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

73044:D0Z67 RS25960
gene id: 73044:D0Z67_RS25960
uniprot id: A0A4P6U2X4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

73044:D0Z67 RS02950
gene id: 73044:D0Z67_RS02950
uniprot id: A0A4P6TRZ0
names: Similarity
messages: Belongs to the peptidase C56 family.

73044:D0Z67 RS26035
gene id: 73044:D0Z67_RS26035
uniprot id: A0A4P6U5D5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

73044:D0Z67 RS17325
gene id: 73044:D0Z67_RS17325
uniprot id: A0A4P6TZ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

73044:D0Z67 RS08865
gene id: 73044:D0Z67_RS08865
uniprot id: A0A4P6TUL1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

73044:D0Z67 RS05430
gene id: 73044:D0Z67_RS05430
uniprot id: A0A4P6TTE4
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

73044:D0Z67 RS17495
gene id: 73044:D0Z67_RS17495
uniprot id: A0A4P6TWB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

73044:D0Z67 RS08710
gene id: 73044:D0Z67_RS08710
uniprot id: A0A4P6TXN7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

73044:D0Z67 RS04995
gene id: 73044:D0Z67_RS04995
uniprot id: A0A4P6TR89
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS17255
gene id: 73044:D0Z67_RS17255
uniprot id: A0A4P6TYE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

73044:D0Z67 RS17345
gene id: 73044:D0Z67_RS17345
uniprot id: A0A4P6U1K2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

73044:D0Z67 RS02245
gene id: 73044:D0Z67_RS02245
uniprot id: A0A4P6TRA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

73044:D0Z67 RS06410
gene id: 73044:D0Z67_RS06410
uniprot id: A0A4P6TT71
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

73044:D0Z67 RS28200
gene id: 73044:D0Z67_RS28200
uniprot id: A0A4P6U6C7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

73044:D0Z67 RS07710
gene id: 73044:D0Z67_RS07710
uniprot id: A0A4P6TS64
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

73044:D0Z67 RS20600
gene id: 73044:D0Z67_RS20600
uniprot id: A0A4P6U2Z0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

73044:D0Z67 RS09970
gene id: 73044:D0Z67_RS09970
uniprot id: A0A4P6TT61
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS19915
gene id: 73044:D0Z67_RS19915
uniprot id: A0A4V0ZZU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

73044:D0Z67 RS12245
gene id: 73044:D0Z67_RS12245
uniprot id: A0A4P6TX14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

73044:D0Z67 RS05850
gene id: 73044:D0Z67_RS05850
uniprot id: A0A4P6TTL0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

73044:D0Z67 RS25465
gene id: 73044:D0Z67_RS25465
uniprot id: A0A4P6U0K9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS21060
gene id: 73044:D0Z67_RS21060
uniprot id: A0A4P6TXY5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

73044:D0Z67 RS09115
gene id: 73044:D0Z67_RS09115
uniprot id: A0A4V0ZZB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

73044:D0Z67 RS12350
gene id: 73044:D0Z67_RS12350
uniprot id: A0A4P6TVY0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

73044:D0Z67 RS04150
gene id: 73044:D0Z67_RS04150
uniprot id: A0A4P6TQH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

73044:D0Z67 RS20240
gene id: 73044:D0Z67_RS20240
uniprot id: A0A4P6TXM2
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS21015
gene id: 73044:D0Z67_RS21015
uniprot id: A0A4V0ZZW7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

73044:D0Z67 RS25340
gene id: 73044:D0Z67_RS25340
uniprot id: A0A4P6U0J0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS21500
gene id: 73044:D0Z67_RS21500
uniprot id: A0A4P6U0V9
names: Similarity
messages: Belongs to the ribF family.

73044:D0Z67 RS11240
gene id: 73044:D0Z67_RS11240
uniprot id: A0A4P6TU15
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

73044:D0Z67 RS10540
gene id: 73044:D0Z67_RS10540
uniprot id: A0A4P6TVC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

73044:D0Z67 RS25280
gene id: 73044:D0Z67_RS25280
uniprot id: A0A4P6U0H9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

73044:D0Z67 RS20065
gene id: 73044:D0Z67_RS20065
uniprot id: A0A4P6TZN1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

73044:D0Z67 RS03865
gene id: 73044:D0Z67_RS03865
uniprot id: A0A4P6TS26
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

73044:D0Z67 RS08325
gene id: 73044:D0Z67_RS08325
uniprot id: A0A4P6TSG2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04795
gene id: 73044:D0Z67_RS04795
uniprot id: A0A4P6TST0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

73044:D0Z67 RS24600
gene id: 73044:D0Z67_RS24600
uniprot id: A0A4P6U2D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

73044:D0Z67 RS03785
gene id: 73044:D0Z67_RS03785
uniprot id: A0A4P6TQB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

73044:D0Z67 RS19535
gene id: 73044:D0Z67_RS19535
uniprot id: A0A4P6TZ52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

73044:D0Z67 RS08060
gene id: 73044:D0Z67_RS08060
uniprot id: A0A4P6TSL2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS11390
gene id: 73044:D0Z67_RS11390
uniprot id: A0A4P6TU45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

73044:D0Z67 RS25900
gene id: 73044:D0Z67_RS25900
uniprot id: A0A4P6TZY9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS17265
gene id: 73044:D0Z67_RS17265
uniprot id: A0A4P6TYZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

73044:D0Z67 RS26195
gene id: 73044:D0Z67_RS26195
uniprot id: A0A4P6U032
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS20590
gene id: 73044:D0Z67_RS20590
uniprot id: A0A4V0ZZW0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

73044:D0Z67 RS02365
gene id: 73044:D0Z67_RS02365
uniprot id: A0A4P6TUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

73044:D0Z67 RS22295
gene id: 73044:D0Z67_RS22295
uniprot id: A0A4P6U1A2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS19940
gene id: 73044:D0Z67_RS19940
uniprot id: A0A4P6TXW6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

73044:D0Z67 RS21525
gene id: 73044:D0Z67_RS21525
uniprot id: A0A4V0ZZX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS12595
gene id: 73044:D0Z67_RS12595
uniprot id: A0A4P6TUN9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

73044:D0Z67 RS03280
gene id: 73044:D0Z67_RS03280
uniprot id: A0A4P6TQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS12605
gene id: 73044:D0Z67_RS12605
uniprot id: A0A4P6TWB2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

73044:D0Z67 RS07685
gene id: 73044:D0Z67_RS07685
uniprot id: A0A4P6TUG0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS10765
gene id: 73044:D0Z67_RS10765
uniprot id: A0A4P6TTS7
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

73044:D0Z67 RS06990
gene id: 73044:D0Z67_RS06990
uniprot id: A0A4P6TUU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

73044:D0Z67 RS08765
gene id: 73044:D0Z67_RS08765
uniprot id: A0A4P6TUY9
names: Similarity
messages: Belongs to the FGGY kinase family.

73044:D0Z67 RS21100
gene id: 73044:D0Z67_RS21100
uniprot id: A0A4P6U058
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

73044:D0Z67 RS10290
gene id: 73044:D0Z67_RS10290
uniprot id: A0A4P6TVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

73044:D0Z67 RS21915
gene id: 73044:D0Z67_RS21915
uniprot id: A0A4P6U3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS06870
gene id: 73044:D0Z67_RS06870
uniprot id: A0A4P6TTP2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

73044:D0Z67 RS21105
gene id: 73044:D0Z67_RS21105
uniprot id: A0A4P6U053
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

73044:D0Z67 RS26470
gene id: 73044:D0Z67_RS26470
uniprot id: A0A4P6U358
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

73044:D0Z67 RS20640
gene id: 73044:D0Z67_RS20640
uniprot id: A0A4P6TXT0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

73044:D0Z67 RS23525
gene id: 73044:D0Z67_RS23525
uniprot id: A0A4P6U151
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

73044:D0Z67 RS05895
gene id: 73044:D0Z67_RS05895
uniprot id: A0A4P6TTA2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

73044:D0Z67 RS11715
gene id: 73044:D0Z67_RS11715
uniprot id: A0A4P6TZ02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

73044:D0Z67 RS08820
gene id: 73044:D0Z67_RS08820
uniprot id: A0A4P6TSM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS24480
gene id: 73044:D0Z67_RS24480
uniprot id: A0A4P6U258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS21185
gene id: 73044:D0Z67_RS21185
uniprot id: A0A4P6U2Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

73044:D0Z67 RS29355
gene id: 73044:D0Z67_RS29355
uniprot id: A0A4P6U3G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WhiB family.
messages: Cytoplasm

73044:D0Z67 RS28340
gene id: 73044:D0Z67_RS28340
uniprot id: A0A4P6U414
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

73044:D0Z67 RS19540
gene id: 73044:D0Z67_RS19540
uniprot id: A0A4P6U2I7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

73044:D0Z67 RS05225
gene id: 73044:D0Z67_RS05225
uniprot id: A0A4P6U1Z0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

73044:D0Z67 RS18170
gene id: 73044:D0Z67_RS18170
uniprot id: A0A4P6U1Z1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS11875
gene id: 73044:D0Z67_RS11875
uniprot id: A0A4P6TUD0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS16840
gene id: 73044:D0Z67_RS16840
uniprot id: A0A4V1A0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

73044:D0Z67 RS13070
gene id: 73044:D0Z67_RS13070
uniprot id: A0A4P6TXB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

73044:D0Z67 RS20010
gene id: 73044:D0Z67_RS20010
uniprot id: A0A4P6TZP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

73044:D0Z67 RS25670
gene id: 73044:D0Z67_RS25670
uniprot id: A0A4P6U5F1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS13835
gene id: 73044:D0Z67_RS13835
uniprot id: A0A4P6TV71
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

73044:D0Z67 RS19585
gene id: 73044:D0Z67_RS19585
uniprot id: A0A4P6TZ62
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS05210
gene id: 73044:D0Z67_RS05210
uniprot id: A0A4P6TW62
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

73044:D0Z67 RS05445
gene id: 73044:D0Z67_RS05445
uniprot id: A0A4P6TST3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

73044:D0Z67 RS05125
gene id: 73044:D0Z67_RS05125
uniprot id: A0A4P6TSW7
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

73044:D0Z67 RS22875
gene id: 73044:D0Z67_RS22875
uniprot id: A0A4P6U1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS16500
gene id: 73044:D0Z67_RS16500
uniprot id: A0A4P6U2F1
names: Similarity
messages: Belongs to the DprA/Smf family.

73044:D0Z67 RS05545
gene id: 73044:D0Z67_RS05545
uniprot id: A0A4P6TT50
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

73044:D0Z67 RS16120
gene id: 73044:D0Z67_RS16120
uniprot id: A0A4P6TYG9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

73044:D0Z67 RS11710
gene id: 73044:D0Z67_RS11710
uniprot id: A0A4P6TVN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

73044:D0Z67 RS02660
gene id: 73044:D0Z67_RS02660
uniprot id: A0A4P6TRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS24770
gene id: 73044:D0Z67_RS24770
uniprot id: A0A4P6U1N1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

73044:D0Z67 RS15435
gene id: 73044:D0Z67_RS15435
uniprot id: A0A4P6TY76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

73044:D0Z67 RS02985
gene id: 73044:D0Z67_RS02985
uniprot id: A0A4P6TQ03
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS03305
gene id: 73044:D0Z67_RS03305
uniprot id: A0A4P6TS41
names: Similarity
messages: Belongs to the DEAD box helicase family.

73044:D0Z67 RS19595
gene id: 73044:D0Z67_RS19595
uniprot id: A0A4P6TXH9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

73044:D0Z67 RS28670
gene id: 73044:D0Z67_RS28670
uniprot id: A0A4P6U1L4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

73044:D0Z67 RS08520
gene id: 73044:D0Z67_RS08520
uniprot id: A0A4P6TUV4
names: Similarity
messages: Belongs to the CdaR family.

73044:D0Z67 RS04515
gene id: 73044:D0Z67_RS04515
uniprot id: A0A4P6TVU6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS08095
gene id: 73044:D0Z67_RS08095
uniprot id: A0A4P6TTZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS17810
gene id: 73044:D0Z67_RS17810
uniprot id: A0A4P6TZA5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

73044:D0Z67 RS24790
gene id: 73044:D0Z67_RS24790
uniprot id: A0A4P6U1D3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS23770
gene id: 73044:D0Z67_RS23770
uniprot id: A0A4P6U179
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

73044:D0Z67 RS22040
gene id: 73044:D0Z67_RS22040
uniprot id: A0A4P6TYW7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

73044:D0Z67 RS10185
gene id: 73044:D0Z67_RS10185
uniprot id: A0A4P6TUZ0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

73044:D0Z67 RS27515
gene id: 73044:D0Z67_RS27515
uniprot id: A0A4P6U2Z8
names: Similarity
messages: Belongs to the pirin family.

73044:D0Z67 RS05770
gene id: 73044:D0Z67_RS05770
uniprot id: A0A4P6TR65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS23220
gene id: 73044:D0Z67_RS23220
uniprot id: A0A4P6U462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS12615
gene id: 73044:D0Z67_RS12615
uniprot id: A0A4P6TWQ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS19760
gene id: 73044:D0Z67_RS19760
uniprot id: A0A4P6U2L8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

73044:D0Z67 RS24390
gene id: 73044:D0Z67_RS24390
uniprot id: A0A4P6TZD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

73044:D0Z67 RS03830
gene id: 73044:D0Z67_RS03830
uniprot id: A0A4P6TQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

73044:D0Z67 RS17330
gene id: 73044:D0Z67_RS17330
uniprot id: A0A4P6TW88
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

73044:D0Z67 RS23195
gene id: 73044:D0Z67_RS23195
uniprot id: A0A4P6U0Z7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

73044:D0Z67 RS03855
gene id: 73044:D0Z67_RS03855
uniprot id: A0A4P6TQC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

73044:D0Z67 RS04705
gene id: 73044:D0Z67_RS04705
uniprot id: A0A4P6TSG0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS26305
gene id: 73044:D0Z67_RS26305
uniprot id: A0A4P6U327
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

73044:D0Z67 RS15510
gene id: 73044:D0Z67_RS15510
uniprot id: A0A4P6TXC2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

73044:D0Z67 RS13865
gene id: 73044:D0Z67_RS13865
uniprot id: A0A4P6TXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS02200
gene id: 73044:D0Z67_RS02200
uniprot id: A0A4P6TPN4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

73044:D0Z67 RS12665
gene id: 73044:D0Z67_RS12665
uniprot id: A0A4P6TWC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS07590
gene id: 73044:D0Z67_RS07590
uniprot id: A0A4P6U2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

73044:D0Z67 RS26590
gene id: 73044:D0Z67_RS26590
uniprot id: A0A4P6U092
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS09770
gene id: 73044:D0Z67_RS09770
uniprot id: A0A4P6TV13
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS22035
gene id: 73044:D0Z67_RS22035
uniprot id: A0A4P6TYJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

73044:D0Z67 RS05670
gene id: 73044:D0Z67_RS05670
uniprot id: A0A4P6TR49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

73044:D0Z67 RS02195
gene id: 73044:D0Z67_RS02195
uniprot id: A0A4P6U3S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

73044:D0Z67 RS04770
gene id: 73044:D0Z67_RS04770
uniprot id: A0A4P6TVY2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

73044:D0Z67 RS11315
gene id: 73044:D0Z67_RS11315
uniprot id: A0A4P6TTQ3
names: Similarity
messages: Belongs to the YoeB family.

73044:D0Z67 RS04140
gene id: 73044:D0Z67_RS04140
uniprot id: A0A4P6TS69
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS15430
gene id: 73044:D0Z67_RS15430
uniprot id: A0A4P6TXJ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS14935
gene id: 73044:D0Z67_RS14935
uniprot id: A0A4P6TV54
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

73044:D0Z67 RS14230
gene id: 73044:D0Z67_RS14230
uniprot id: A0A4P6TV25
names: Similarity
messages: Belongs to the SCO1/2 family.

73044:D0Z67 RS11405
gene id: 73044:D0Z67_RS11405
uniprot id: A0A4P6TVT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS16210
gene id: 73044:D0Z67_RS16210
uniprot id: A0A4P6U265
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

73044:D0Z67 RS17660
gene id: 73044:D0Z67_RS17660
uniprot id: A0A4P6TYK3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

73044:D0Z67 RS01480
gene id: 73044:D0Z67_RS01480
uniprot id: A0A4P6TUH4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

73044:D0Z67 RS23320
gene id: 73044:D0Z67_RS23320
uniprot id: A0A4V1A007
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS20260
gene id: 73044:D0Z67_RS20260
uniprot id: A0A4P6U2U2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS20915
gene id: 73044:D0Z67_RS20915
uniprot id: A0A4P6TZQ2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

73044:D0Z67 RS03675
gene id: 73044:D0Z67_RS03675
uniprot id: A0A4V0ZZ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

73044:D0Z67 RS23635
gene id: 73044:D0Z67_RS23635
uniprot id: A0A4P6U0Y6
names: Subunit
messages: Homotetramer.

73044:D0Z67 RS20505
gene id: 73044:D0Z67_RS20505
uniprot id: A0A4P6TZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS29430
gene id: 73044:D0Z67_RS29430
uniprot id: A0A4V1A0G4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

73044:D0Z67 RS00170
gene id: 73044:D0Z67_RS00170
uniprot id: A0A4P6TTZ3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS21205
gene id: 73044:D0Z67_RS21205
uniprot id: A0A4P6U4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS17500
gene id: 73044:D0Z67_RS17500
uniprot id: A0A4V0ZZQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

73044:D0Z67 RS07415
gene id: 73044:D0Z67_RS07415
uniprot id: A0A4P6TTN7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

73044:D0Z67 RS21245
gene id: 73044:D0Z67_RS21245
uniprot id: A0A4P6TY10
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS04445
gene id: 73044:D0Z67_RS04445
uniprot id: A0A4P6TSW9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

73044:D0Z67 RS06155
gene id: 73044:D0Z67_RS06155
uniprot id: A0A4P6TRR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

73044:D0Z67 RS02850
gene id: 73044:D0Z67_RS02850
uniprot id: A0A4V0ZZ00
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS07380
gene id: 73044:D0Z67_RS07380
uniprot id: A0A4P6TUZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

73044:D0Z67 RS27395
gene id: 73044:D0Z67_RS27395
uniprot id: A0A4P6U126
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

73044:D0Z67 RS14495
gene id: 73044:D0Z67_RS14495
uniprot id: A0A4P6U073
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

73044:D0Z67 RS10160
gene id: 73044:D0Z67_RS10160
uniprot id: A0A4P6TV77
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

73044:D0Z67 RS02635
gene id: 73044:D0Z67_RS02635
uniprot id: A0A4P6TRH0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS25905
gene id: 73044:D0Z67_RS25905
uniprot id: A0A4V1A052
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS17240
gene id: 73044:D0Z67_RS17240
uniprot id: A0A4P6TWG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

73044:D0Z67 RS25625
gene id: 73044:D0Z67_RS25625
uniprot id: A0A4P6U4W5
names: Similarity
messages: Belongs to the hyi family.

73044:D0Z67 RS04465
gene id: 73044:D0Z67_RS04465
uniprot id: A0A4P6TVT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

73044:D0Z67 RS05960
gene id: 73044:D0Z67_RS05960
uniprot id: A0A4V0ZZ54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

73044:D0Z67 RS16105
gene id: 73044:D0Z67_RS16105
uniprot id: A0A4P6TYL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

73044:D0Z67 RS19090
gene id: 73044:D0Z67_RS19090
uniprot id: A0A4P6TXJ1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

73044:D0Z67 RS14610
gene id: 73044:D0Z67_RS14610
uniprot id: A0A4P6TV86
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

73044:D0Z67 RS22165
gene id: 73044:D0Z67_RS22165
uniprot id: A0A4P6U0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

73044:D0Z67 RS03295
gene id: 73044:D0Z67_RS03295
uniprot id: A0A4P6TT68
names: Similarity
messages: Belongs to the ABC transporter superfamily.

73044:D0Z67 RS00860
gene id: 73044:D0Z67_RS00860
uniprot id: A0A4P6TP32
names: Similarity
messages: Belongs to the universal stress protein A family.

73044:D0Z67 RS05390
gene id: 73044:D0Z67_RS05390
uniprot id: A0A4P6TSS0
names: Similarity
messages: Belongs to the peptidase S45 family.

73044:D0Z67 RS27190
gene id: 73044:D0Z67_RS27190
uniprot id: A0A4V1A074
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

73044:D0Z67 RS10475
gene id: 73044:D0Z67_RS10475
uniprot id: A0A4P6TVC9
names: Similarity
messages: Belongs to the peptidase C40 family.

73044:D0Z67 RS25580
gene id: 73044:D0Z67_RS25580
uniprot id: A0A4P6U1W0
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06345
gene id: 73044:D0Z67_RS06345
uniprot id: A0A4P6TTU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS20710
gene id: 73044:D0Z67_RS20710
uniprot id: A0A4V0ZZW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS13130
gene id: 73044:D0Z67_RS13130
uniprot id: A0A4P6TUW7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS20390
gene id: 73044:D0Z67_RS20390
uniprot id: A0A4P6U0E9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06525
gene id: 73044:D0Z67_RS06525
uniprot id: A0A4P6TRN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

73044:D0Z67 RS12090
gene id: 73044:D0Z67_RS12090
uniprot id: A0A4P6TZ56
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

73044:D0Z67 RS03270
gene id: 73044:D0Z67_RS03270
uniprot id: A0A4P6TRR4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS15600
gene id: 73044:D0Z67_RS15600
uniprot id: A0A4P6TXM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

73044:D0Z67 RS28630
gene id: 73044:D0Z67_RS28630
uniprot id: A0A4P6U3L5
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

73044:D0Z67 RS18670
gene id: 73044:D0Z67_RS18670
uniprot id: A0A4P6TYR1
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

73044:D0Z67 RS07955
gene id: 73044:D0Z67_RS07955
uniprot id: A0A4P6TU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS16300
gene id: 73044:D0Z67_RS16300
uniprot id: A0A4V0ZZN4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS10700
gene id: 73044:D0Z67_RS10700
uniprot id: A0A4P6TTG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

73044:D0Z67 RS21300
gene id: 73044:D0Z67_RS21300
uniprot id: A0A4P6TY18
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

73044:D0Z67 RS07745
gene id: 73044:D0Z67_RS07745
uniprot id: Q9Z6I4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

73044:D0Z67 RS16810
gene id: 73044:D0Z67_RS16810
uniprot id: A0A4P6TY64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS26120
gene id: 73044:D0Z67_RS26120
uniprot id: A0A4P6U0V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

73044:D0Z67 RS06255
gene id: 73044:D0Z67_RS06255
uniprot id: A0A4P6TWJ7
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

73044:D0Z67 RS24905
gene id: 73044:D0Z67_RS24905
uniprot id: A0A4V1A0E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS21815
gene id: 73044:D0Z67_RS21815
uniprot id: A0A4P6U4L9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

73044:D0Z67 RS02685
gene id: 73044:D0Z67_RS02685
uniprot id: A0A4P6TRH9
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

73044:D0Z67 RS23900
gene id: 73044:D0Z67_RS23900
uniprot id: A0A4P6U120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

73044:D0Z67 RS04115
gene id: 73044:D0Z67_RS04115
uniprot id: A0A4P6TSF0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

73044:D0Z67 RS06140
gene id: 73044:D0Z67_RS06140
uniprot id: A0A4P6U3Y6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

73044:D0Z67 RS20155
gene id: 73044:D0Z67_RS20155
uniprot id: A0A4P6U0B8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS03540
gene id: 73044:D0Z67_RS03540
uniprot id: A0A4P6TSF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS15035
gene id: 73044:D0Z67_RS15035
uniprot id: A0A4P6TY56
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS17115
gene id: 73044:D0Z67_RS17115
uniprot id: A0A4V0ZZP8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS26255
gene id: 73044:D0Z67_RS26255
uniprot id: A0A4P6U042
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS09485
gene id: 73044:D0Z67_RS09485
uniprot id: A0A4P6TVV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

73044:D0Z67 RS15125
gene id: 73044:D0Z67_RS15125
uniprot id: A0A4P6TVF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

73044:D0Z67 RS21630
gene id: 73044:D0Z67_RS21630
uniprot id: A0A4V0ZZX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

73044:D0Z67 RS06665
gene id: 73044:D0Z67_RS06665
uniprot id: A0A4V0ZZ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

73044:D0Z67 RS18715
gene id: 73044:D0Z67_RS18715
uniprot id: A0A4P6TWZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

73044:D0Z67 RS21085
gene id: 73044:D0Z67_RS21085
uniprot id: A0A4P6TY50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

73044:D0Z67 RS18380
gene id: 73044:D0Z67_RS18380
uniprot id: A0A4V0ZZS1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

73044:D0Z67 RS12230
gene id: 73044:D0Z67_RS12230
uniprot id: A0A4P6TZ75
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

73044:D0Z67 RS07740
gene id: 73044:D0Z67_RS07740
uniprot id: Q9Z6I5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

73044:D0Z67 RS09105
gene id: 73044:D0Z67_RS09105
uniprot id: A0A4P6TSR9
names: Similarity
messages: Belongs to the DapA family.

73044:D0Z67 RS16785
gene id: 73044:D0Z67_RS16785
uniprot id: A0A4P6TXW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS21035
gene id: 73044:D0Z67_RS21035
uniprot id: A0A4P6TYF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

73044:D0Z67 RS28660
gene id: 73044:D0Z67_RS28660
uniprot id: A0A4P6U3I0
names: Similarity
messages: Belongs to the HypD family.

73044:D0Z67 RS27400
gene id: 73044:D0Z67_RS27400
uniprot id: A0A4P6U1D9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS10845
gene id: 73044:D0Z67_RS10845
uniprot id: A0A4P6TTI8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

73044:D0Z67 RS27565
gene id: 73044:D0Z67_RS27565
uniprot id: A0A4P6U308
names: Similarity
messages: Belongs to the cytochrome P450 family.

73044:D0Z67 RS00540
gene id: 73044:D0Z67_RS00540
uniprot id: A0A4P6TQW7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

73044:D0Z67 RS16825
gene id: 73044:D0Z67_RS16825
uniprot id: A0A4P6TW04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

73044:D0Z67 RS26270
gene id: 73044:D0Z67_RS26270
uniprot id: A0A4P6U5H0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

73044:D0Z67 RS12870
gene id: 73044:D0Z67_RS12870
uniprot id: A0A4P6U213
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04265
gene id: 73044:D0Z67_RS04265
uniprot id: A0A4P6TTL5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

73044:D0Z67 RS12980
gene id: 73044:D0Z67_RS12980
uniprot id: A0A4P6TUD3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

73044:D0Z67 RS27770
gene id: 73044:D0Z67_RS27770
uniprot id: A0A4P6U3R9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS19805
gene id: 73044:D0Z67_RS19805
uniprot id: A0A4V0ZZU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

73044:D0Z67 RS09375
gene id: 73044:D0Z67_RS09375
uniprot id: A0A4P6TT59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

73044:D0Z67 RS07200
gene id: 73044:D0Z67_RS07200
uniprot id: A0A4P6TTK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

73044:D0Z67 RS03220
gene id: 73044:D0Z67_RS03220
uniprot id: A0A4P6TV92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

73044:D0Z67 RS20480
gene id: 73044:D0Z67_RS20480
uniprot id: A0A4P6U2X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

73044:D0Z67 RS00870
gene id: 73044:D0Z67_RS00870
uniprot id: A0A4P6TS65
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

73044:D0Z67 RS24030
gene id: 73044:D0Z67_RS24030
uniprot id: A0A4P6TZY4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

73044:D0Z67 RS17375
gene id: 73044:D0Z67_RS17375
uniprot id: A0A4P6TZ16
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

73044:D0Z67 RS06035
gene id: 73044:D0Z67_RS06035
uniprot id: A0A4P6TRP5
names: Similarity
messages: Belongs to the peptidase S8 family.

73044:D0Z67 RS21325
gene id: 73044:D0Z67_RS21325
uniprot id: A0A4P6TYJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

73044:D0Z67 RS06900
gene id: 73044:D0Z67_RS06900
uniprot id: A0A4V1A0B8
names: Similarity
messages: Belongs to the peptidase M1 family.

73044:D0Z67 RS07340
gene id: 73044:D0Z67_RS07340
uniprot id: A0A4P6TUA5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS26570
gene id: 73044:D0Z67_RS26570
uniprot id: A0A4P6U306
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS14270
gene id: 73044:D0Z67_RS14270
uniprot id: A0A4P6TWS2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS11460
gene id: 73044:D0Z67_RS11460
uniprot id: A0A4P6TVS6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

73044:D0Z67 RS17970
gene id: 73044:D0Z67_RS17970
uniprot id: A0A4P6TZE0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

73044:D0Z67 RS23780
gene id: 73044:D0Z67_RS23780
uniprot id: A0A4P6TZ34
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03910
gene id: 73044:D0Z67_RS03910
uniprot id: A0A4P6TSL6
names: Similarity
messages: Belongs to the GcvT family.

73044:D0Z67 RS28910
gene id: 73044:D0Z67_RS28910
uniprot id: A0A4P6U402
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS28590
gene id: 73044:D0Z67_RS28590
uniprot id: A0A4P6U188
names: Similarity
messages: Belongs to the phosphohexose mutase family.

73044:D0Z67 RS10035
gene id: 73044:D0Z67_RS10035
uniprot id: A0A4P6TUW2
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS11010
gene id: 73044:D0Z67_RS11010
uniprot id: A0A4P6TW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS19300
gene id: 73044:D0Z67_RS19300
uniprot id: A0A4P6TXD3
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04250
gene id: 73044:D0Z67_RS04250
uniprot id: A0A4P6TVP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

73044:D0Z67 RS16485
gene id: 73044:D0Z67_RS16485
uniprot id: A0A4V0ZZN7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

73044:D0Z67 RS14385
gene id: 73044:D0Z67_RS14385
uniprot id: A0A4P6U049
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

73044:D0Z67 RS12565
gene id: 73044:D0Z67_RS12565
uniprot id: A0A4V0ZZH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS10165
gene id: 73044:D0Z67_RS10165
uniprot id: A0A4P6TV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

73044:D0Z67 RS11530
gene id: 73044:D0Z67_RS11530
uniprot id: A0A4P6TTT3
names: Similarity
messages: Belongs to the CFA/CMAS family.

73044:D0Z67 RS27820
gene id: 73044:D0Z67_RS27820
uniprot id: A0A4P6U391
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

73044:D0Z67 RS14480
gene id: 73044:D0Z67_RS14480
uniprot id: A0A4V0ZZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

73044:D0Z67 RS13690
gene id: 73044:D0Z67_RS13690
uniprot id: A0A4V0ZZI9
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

73044:D0Z67 RS25250
gene id: 73044:D0Z67_RS25250
uniprot id: A0A4P6U2M0
names: Similarity
messages: Belongs to the universal stress protein A family.

73044:D0Z67 RS09710
gene id: 73044:D0Z67_RS09710
uniprot id: A0A4P6TV03
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

73044:D0Z67 RS13905
gene id: 73044:D0Z67_RS13905
uniprot id: A0A4P6U223
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

73044:D0Z67 RS07565
gene id: 73044:D0Z67_RS07565
uniprot id: A0A4P6TUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS15985
gene id: 73044:D0Z67_RS15985
uniprot id: A0A4P6TYK1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

73044:D0Z67 RS25500
gene id: 73044:D0Z67_RS25500
uniprot id: A0A4V1A045
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS19050
gene id: 73044:D0Z67_RS19050
uniprot id: A0A4P6TZS9
names: Similarity
messages: Belongs to the UPF0162 family.

73044:D0Z67 RS17585
gene id: 73044:D0Z67_RS17585
uniprot id: A0A4P6TYJ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS07775
gene id: 73044:D0Z67_RS07775
uniprot id: A0A4P6TV61
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

73044:D0Z67 RS15235
gene id: 73044:D0Z67_RS15235
uniprot id: A0A4P6U0J9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS01005
gene id: 73044:D0Z67_RS01005
uniprot id: A0A4P6TRA5
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS14315
gene id: 73044:D0Z67_RS14315
uniprot id: A0A4P6TUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

73044:D0Z67 RS12435
gene id: 73044:D0Z67_RS12435
uniprot id: A0A4P6TX39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS03950
gene id: 73044:D0Z67_RS03950
uniprot id: A0A4P6TSB8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08475
gene id: 73044:D0Z67_RS08475
uniprot id: A0A4P6TSH6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS07060
gene id: 73044:D0Z67_RS07060
uniprot id: A0A4P6TTR7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

73044:D0Z67 RS00595
gene id: 73044:D0Z67_RS00595
uniprot id: A0A4P6TS19
names: Similarity
messages: Belongs to the peptidase M1 family.

73044:D0Z67 RS04765
gene id: 73044:D0Z67_RS04765
uniprot id: A0A4P6TSG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

73044:D0Z67 RS20000
gene id: 73044:D0Z67_RS20000
uniprot id: A0A4P6TXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

73044:D0Z67 RS02090
gene id: 73044:D0Z67_RS02090
uniprot id: A0A4P6U3L2
names: Similarity
messages: Belongs to the CdaR family.

73044:D0Z67 RS10740
gene id: 73044:D0Z67_RS10740
uniprot id: A0A4P6TTH1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08590
gene id: 73044:D0Z67_RS08590
uniprot id: A0A4P6U4S6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

73044:D0Z67 RS10980
gene id: 73044:D0Z67_RS10980
uniprot id: A0A4P6TTX0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

73044:D0Z67 RS23380
gene id: 73044:D0Z67_RS23380
uniprot id: A0A4V1A0E6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

73044:D0Z67 RS07215
gene id: 73044:D0Z67_RS07215
uniprot id: A0A4P6TS77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

73044:D0Z67 RS07555
gene id: 73044:D0Z67_RS07555
uniprot id: A0A4P6TTZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

73044:D0Z67 RS21595
gene id: 73044:D0Z67_RS21595
uniprot id: A0A4P6TYD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

73044:D0Z67 RS02115
gene id: 73044:D0Z67_RS02115
uniprot id: A0A4P6U4G3
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS05745
gene id: 73044:D0Z67_RS05745
uniprot id: A0A4P6TRK2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

73044:D0Z67 RS24235
gene id: 73044:D0Z67_RS24235
uniprot id: A0A4V1A023
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS25860
gene id: 73044:D0Z67_RS25860
uniprot id: A0A4P6U5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

73044:D0Z67 RS19575
gene id: 73044:D0Z67_RS19575
uniprot id: A0A4P6TXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS09565
gene id: 73044:D0Z67_RS09565
uniprot id: A0A4P6TSY8
names: Similarity
messages: Belongs to the peptidase M1 family.

73044:D0Z67 RS12440
gene id: 73044:D0Z67_RS12440
uniprot id: A0A4P6TW84
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

73044:D0Z67 RS23110
gene id: 73044:D0Z67_RS23110
uniprot id: A0A4P6U5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

73044:D0Z67 RS21030
gene id: 73044:D0Z67_RS21030
uniprot id: A0A4P6TY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

73044:D0Z67 RS22065
gene id: 73044:D0Z67_RS22065
uniprot id: A0A4P6TYD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

73044:D0Z67 RS19630
gene id: 73044:D0Z67_RS19630
uniprot id: A0A4P6TXC1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

73044:D0Z67 RS10965
gene id: 73044:D0Z67_RS10965
uniprot id: A0A4P6TVB5
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

73044:D0Z67 RS22215
gene id: 73044:D0Z67_RS22215
uniprot id: A0A4P6TYZ6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

73044:D0Z67 RS04090
gene id: 73044:D0Z67_RS04090
uniprot id: A0A4P6TS61
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS21465
gene id: 73044:D0Z67_RS21465
uniprot id: A0A4P6U0X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

73044:D0Z67 RS09220
gene id: 73044:D0Z67_RS09220
uniprot id: A0A4P6TST7
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

73044:D0Z67 RS13345
gene id: 73044:D0Z67_RS13345
uniprot id: A0A4P6TX17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS08540
gene id: 73044:D0Z67_RS08540
uniprot id: A0A4P6TXK9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

73044:D0Z67 RS18275
gene id: 73044:D0Z67_RS18275
uniprot id: A0A4V0ZZR9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

73044:D0Z67 RS21990
gene id: 73044:D0Z67_RS21990
uniprot id: A0A4P6U4R1
names: Similarity
messages: Belongs to the RelA/SpoT family.

73044:D0Z67 RS17995
gene id: 73044:D0Z67_RS17995
uniprot id: A0A4V0ZZR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

73044:D0Z67 RS15885
gene id: 73044:D0Z67_RS15885
uniprot id: A0A4P6TXR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

73044:D0Z67 RS14615
gene id: 73044:D0Z67_RS14615
uniprot id: A0A4P6TVI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

73044:D0Z67 RS14255
gene id: 73044:D0Z67_RS14255
uniprot id: A0A4P6TXL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

73044:D0Z67 RS12025
gene id: 73044:D0Z67_RS12025
uniprot id: A0A4P6TVT1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS13140
gene id: 73044:D0Z67_RS13140
uniprot id: A0A4P6TWH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS04875
gene id: 73044:D0Z67_RS04875
uniprot id: A0A4P6TQV2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

73044:D0Z67 RS23855
gene id: 73044:D0Z67_RS23855
uniprot id: A0A4P6TZV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

73044:D0Z67 RS04655
gene id: 73044:D0Z67_RS04655
uniprot id: A0A4P6TVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

73044:D0Z67 RS05460
gene id: 73044:D0Z67_RS05460
uniprot id: A0A4P6U1P0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS15670
gene id: 73044:D0Z67_RS15670
uniprot id: A0A4V0ZZM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS03315
gene id: 73044:D0Z67_RS03315
uniprot id: A0A4P6TQ46
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS18080
gene id: 73044:D0Z67_RS18080
uniprot id: A0A4P6TX36
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

73044:D0Z67 RS05090
gene id: 73044:D0Z67_RS05090
uniprot id: A0A4V0ZZ39
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

73044:D0Z67 RS07185
gene id: 73044:D0Z67_RS07185
uniprot id: A0A4P6TU78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

73044:D0Z67 RS22305
gene id: 73044:D0Z67_RS22305
uniprot id: A0A4V0ZZY9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

73044:D0Z67 RS03260
gene id: 73044:D0Z67_RS03260
uniprot id: A0A4P6TQ34
names: Similarity
messages: Belongs to the peptidase C40 family.

73044:D0Z67 RS02515
gene id: 73044:D0Z67_RS02515
uniprot id: A0A4P6TPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

73044:D0Z67 RS19845
gene id: 73044:D0Z67_RS19845
uniprot id: A0A4P6U069
names: Similarity
messages: Belongs to the peptidase C40 family.

73044:D0Z67 RS06565
gene id: 73044:D0Z67_RS06565
uniprot id: A0A4P6TT98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

73044:D0Z67 RS28710
gene id: 73044:D0Z67_RS28710
uniprot id: A0A4V1A0A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS04970
gene id: 73044:D0Z67_RS04970
uniprot id: A0A4P6TQT9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS07170
gene id: 73044:D0Z67_RS07170
uniprot id: A0A4P6TUW4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

73044:D0Z67 RS19250
gene id: 73044:D0Z67_RS19250
uniprot id: A0A4P6TZX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS03300
gene id: 73044:D0Z67_RS03300
uniprot id: A0A4P6TS20
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08320
gene id: 73044:D0Z67_RS08320
uniprot id: A0A4P6TXH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

73044:D0Z67 RS12925
gene id: 73044:D0Z67_RS12925
uniprot id: A0A4P6TUC5
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS18645
gene id: 73044:D0Z67_RS18645
uniprot id: A0A4P6TZ21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS12715
gene id: 73044:D0Z67_RS12715
uniprot id: A0A4P6TUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

73044:D0Z67 RS28285
gene id: 73044:D0Z67_RS28285
uniprot id: A0A4P6U371
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

73044:D0Z67 RS12075
gene id: 73044:D0Z67_RS12075
uniprot id: A0A4V1A0C7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS25565
gene id: 73044:D0Z67_RS25565
uniprot id: A0A4P6U2R4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS13235
gene id: 73044:D0Z67_RS13235
uniprot id: A0A4P6TUH0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

73044:D0Z67 RS22880
gene id: 73044:D0Z67_RS22880
uniprot id: A0A4P6TYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS18295
gene id: 73044:D0Z67_RS18295
uniprot id: A0A4P6TX73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

73044:D0Z67 RS13635
gene id: 73044:D0Z67_RS13635
uniprot id: A0A4P6TWI1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

73044:D0Z67 RS11720
gene id: 73044:D0Z67_RS11720
uniprot id: A0A4P6TTZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

73044:D0Z67 RS19190
gene id: 73044:D0Z67_RS19190
uniprot id: A0A4P6TXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS26360
gene id: 73044:D0Z67_RS26360
uniprot id: A0A4P6U336
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

73044:D0Z67 RS06835
gene id: 73044:D0Z67_RS06835
uniprot id: A0A4V0ZZ70
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS13500
gene id: 73044:D0Z67_RS13500
uniprot id: A0A4P6TX47
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

73044:D0Z67 RS16280
gene id: 73044:D0Z67_RS16280
uniprot id: A0A4P6TXX6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS06770
gene id: 73044:D0Z67_RS06770
uniprot id: A0A4P6TU11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

73044:D0Z67 RS16005
gene id: 73044:D0Z67_RS16005
uniprot id: A0A4P6TYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS14920
gene id: 73044:D0Z67_RS14920
uniprot id: A0A4P6TXA3
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS03705
gene id: 73044:D0Z67_RS03705
uniprot id: A0A4P6TTD0
names: Similarity
messages: Belongs to the universal stress protein A family.

73044:D0Z67 RS17180
gene id: 73044:D0Z67_RS17180
uniprot id: A0A4P6TY26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

73044:D0Z67 RS17165
gene id: 73044:D0Z67_RS17165
uniprot id: A0A4P6TYX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

73044:D0Z67 RS28360
gene id: 73044:D0Z67_RS28360
uniprot id: A0A4P6U6G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

73044:D0Z67 RS02930
gene id: 73044:D0Z67_RS02930
uniprot id: A0A4P6TPZ5
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

73044:D0Z67 RS06540
gene id: 73044:D0Z67_RS06540
uniprot id: A0A4P6TTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

73044:D0Z67 RS13725
gene id: 73044:D0Z67_RS13725
uniprot id: A0A4P6TWS7
names: Subcellular Location Annotation
messages: Cytoplasm

73044:D0Z67 RS05995
gene id: 73044:D0Z67_RS05995
uniprot id: A0A4P6TT95
names: Similarity
messages: Belongs to the peptidase U62 family.

73044:D0Z67 RS03050
gene id: 73044:D0Z67_RS03050
uniprot id: A0A4P6TV68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

73044:D0Z67 RS17270
gene id: 73044:D0Z67_RS17270
uniprot id: A0A4P6U4T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

73044:D0Z67 RS00190
gene id: 73044:D0Z67_RS00190
uniprot id: A0A4P6TP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

73044:D0Z67 RS21130
gene id: 73044:D0Z67_RS21130
uniprot id: A0A4P6TZT7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

73044:D0Z67 RS22985
gene id: 73044:D0Z67_RS22985
uniprot id: A0A4P6TYR8
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09020
gene id: 73044:D0Z67_RS09020
uniprot id: A0A4P6TT09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

73044:D0Z67 RS16060
gene id: 73044:D0Z67_RS16060
uniprot id: A0A4P6TXT5
names: Similarity
messages: Belongs to the group II decarboxylase family.

73044:D0Z67 RS02925
gene id: 73044:D0Z67_RS02925
uniprot id: A0A4P6U1V8
names: Similarity
messages: Belongs to the CdaR family.

73044:D0Z67 RS11440
gene id: 73044:D0Z67_RS11440
uniprot id: A0A4P6TTU5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

73044:D0Z67 RS24395
gene id: 73044:D0Z67_RS24395
uniprot id: A0A4V1A026
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

73044:D0Z67 RS08380
gene id: 73044:D0Z67_RS08380
uniprot id: A0A4P6TXI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS13455
gene id: 73044:D0Z67_RS13455
uniprot id: A0A4P6TUK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

73044:D0Z67 RS20420
gene id: 73044:D0Z67_RS20420
uniprot id: A0A4V1A0E1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

73044:D0Z67 RS28435
gene id: 73044:D0Z67_RS28435
uniprot id: A0A4P6U3T7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS09225
gene id: 73044:D0Z67_RS09225
uniprot id: A0A4V0ZZB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

73044:D0Z67 RS24575
gene id: 73044:D0Z67_RS24575
uniprot id: A0A4P6TZX0
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

73044:D0Z67 RS20530
gene id: 73044:D0Z67_RS20530
uniprot id: A0A4P6TZK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

73044:D0Z67 RS09145
gene id: 73044:D0Z67_RS09145
uniprot id: A0A4P6TUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

73044:D0Z67 RS07580
gene id: 73044:D0Z67_RS07580
uniprot id: A0A4P6TTR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

73044:D0Z67 RS19135
gene id: 73044:D0Z67_RS19135
uniprot id: A0A4P6TXA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

73044:D0Z67 RS11160
gene id: 73044:D0Z67_RS11160
uniprot id: A0A4P6TTN1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS18210
gene id: 73044:D0Z67_RS18210
uniprot id: A0A4V0ZZR8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

73044:D0Z67 RS22885
gene id: 73044:D0Z67_RS22885
uniprot id: A0A4V0ZZZ9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS24120
gene id: 73044:D0Z67_RS24120
uniprot id: A0A4P6U146
names: Similarity
messages: Belongs to the peptidase S66 family.

73044:D0Z67 RS20970
gene id: 73044:D0Z67_RS20970
uniprot id: A0A4P6U350
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

73044:D0Z67 RS26765
gene id: 73044:D0Z67_RS26765
uniprot id: A0A4V1A067
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

73044:D0Z67 RS05055
gene id: 73044:D0Z67_RS05055
uniprot id: A0A4P6TTZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

73044:D0Z67 RS07815
gene id: 73044:D0Z67_RS07815
uniprot id: A0A4P6TX94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

73044:D0Z67 RS09120
gene id: 73044:D0Z67_RS09120
uniprot id: A0A4P6TUF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

73044:D0Z67 RS16090
gene id: 73044:D0Z67_RS16090
uniprot id: A0A4P6U103
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

73044:D0Z67 RS15440
gene id: 73044:D0Z67_RS15440
uniprot id: A0A4P6TVE1
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS28410
gene id: 73044:D0Z67_RS28410
uniprot id: A0A4P6U6G9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS24025
gene id: 73044:D0Z67_RS24025
uniprot id: A0A4P6TZH9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

73044:D0Z67 RS26900
gene id: 73044:D0Z67_RS26900
uniprot id: A0A4P6U3C7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

73044:D0Z67 RS07730
gene id: 73044:D0Z67_RS07730
uniprot id: A0A4P6TU21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

73044:D0Z67 RS09545
gene id: 73044:D0Z67_RS09545
uniprot id: A0A4P6TVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

73044:D0Z67 RS26825
gene id: 73044:D0Z67_RS26825
uniprot id: A0A4P6U0C4
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS02400
gene id: 73044:D0Z67_RS02400
uniprot id: A0A4P6TRW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

73044:D0Z67 RS02085
gene id: 73044:D0Z67_RS02085
uniprot id: A0A4P6TRI6
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS01855
gene id: 73044:D0Z67_RS01855
uniprot id: A0A4P6TSK0
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

73044:D0Z67 RS07465
gene id: 73044:D0Z67_RS07465
uniprot id: A0A4P6TS05
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

73044:D0Z67 RS03275
gene id: 73044:D0Z67_RS03275
uniprot id: A0A4P6TV99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

73044:D0Z67 RS10330
gene id: 73044:D0Z67_RS10330
uniprot id: A0A4P6TTL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

73044:D0Z67 RS08085
gene id: 73044:D0Z67_RS08085
uniprot id: A0A4P6TSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

73044:D0Z67 RS21255
gene id: 73044:D0Z67_RS21255
uniprot id: A0A4P6TZV8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

73044:D0Z67 RS25630
gene id: 73044:D0Z67_RS25630
uniprot id: A0A4V1A047
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS01605
gene id: 73044:D0Z67_RS01605
uniprot id: A0A4P6TPD7
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS08470
gene id: 73044:D0Z67_RS08470
uniprot id: A0A4P6TUU0
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

73044:D0Z67 RS13065
gene id: 73044:D0Z67_RS13065
uniprot id: A0A4P6TUV9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

73044:D0Z67 RS16315
gene id: 73044:D0Z67_RS16315
uniprot id: A0A4P6U140
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

73044:D0Z67 RS19690
gene id: 73044:D0Z67_RS19690
uniprot id: A0A4P6TXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

73044:D0Z67 RS15465
gene id: 73044:D0Z67_RS15465
uniprot id: A0A4P6TVL7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

73044:D0Z67 RS00130
gene id: 73044:D0Z67_RS00130
uniprot id: A0A4P6TP29
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

73044:D0Z67 RS22900
gene id: 73044:D0Z67_RS22900
uniprot id: A0A4P6TYZ9
names: Subcellular Location Annotation
messages: Membrane

73044:D0Z67 RS04010
gene id: 73044:D0Z67_RS04010
uniprot id: A0A4P6TSC7
names: Subcellular Location Annotation
messages: Membrane