717605:THECO RS00100
gene id: 717605:THECO_RS00100
uniprot id: L0E7L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS02405
gene id: 717605:THECO_RS02405
uniprot id: L0E8T6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

717605:THECO RS04785
gene id: 717605:THECO_RS04785
uniprot id: L0EBW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

717605:THECO RS13890
gene id: 717605:THECO_RS13890
uniprot id: L0EGM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18660
gene id: 717605:THECO_RS18660
uniprot id: L0EHZ0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

717605:THECO RS01925
gene id: 717605:THECO_RS01925
uniprot id: L0E8J0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS10480
gene id: 717605:THECO_RS10480
uniprot id: L0EEZ7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS16780
gene id: 717605:THECO_RS16780
uniprot id: L0EJT4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS05765
gene id: 717605:THECO_RS05765
uniprot id: L0EAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09090
gene id: 717605:THECO_RS09090
uniprot id: L0EFR2
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

717605:THECO RS02785
gene id: 717605:THECO_RS02785
uniprot id: L0E915
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS11730
gene id: 717605:THECO_RS11730
uniprot id: L0EFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

717605:THECO RS04560
gene id: 717605:THECO_RS04560
uniprot id: L0EBX7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

717605:THECO RS18895
gene id: 717605:THECO_RS18895
uniprot id: L0EKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

717605:THECO RS15320
gene id: 717605:THECO_RS15320
uniprot id: L0EJ66
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS11575
gene id: 717605:THECO_RS11575
uniprot id: L0EH51
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS16980
gene id: 717605:THECO_RS16980
uniprot id: L0EIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

717605:THECO RS00370
gene id: 717605:THECO_RS00370
uniprot id: L0E7U1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS02020
gene id: 717605:THECO_RS02020
uniprot id: L0EAB5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

717605:THECO RS08805
gene id: 717605:THECO_RS08805
uniprot id: L0EDQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

717605:THECO RS01255
gene id: 717605:THECO_RS01255
uniprot id: G4EC90
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS18770
gene id: 717605:THECO_RS18770
uniprot id: L0EKS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

717605:THECO RS04370
gene id: 717605:THECO_RS04370
uniprot id: L0EJT4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS12950
gene id: 717605:THECO_RS12950
uniprot id: L0EHV7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

717605:THECO RS13845
gene id: 717605:THECO_RS13845
uniprot id: L0EF86
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

717605:THECO RS07525
gene id: 717605:THECO_RS07525
uniprot id: L0ED13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS16200
gene id: 717605:THECO_RS16200
uniprot id: L0EIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS05705
gene id: 717605:THECO_RS05705
uniprot id: L0ECE4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

717605:THECO RS01380
gene id: 717605:THECO_RS01380
uniprot id: L0EA55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

717605:THECO RS18105
gene id: 717605:THECO_RS18105
uniprot id: L0EHL2
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

717605:THECO RS07385
gene id: 717605:THECO_RS07385
uniprot id: L0EBL8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

717605:THECO RS08860
gene id: 717605:THECO_RS08860
uniprot id: L0ECE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

717605:THECO RS17290
gene id: 717605:THECO_RS17290
uniprot id: L0EIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09330
gene id: 717605:THECO_RS09330
uniprot id: L0EEJ2
names: Similarity
messages: Belongs to the GerABKA family.

717605:THECO RS16840
gene id: 717605:THECO_RS16840
uniprot id: L0EJU0
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS06605
gene id: 717605:THECO_RS06605
uniprot id: L0ED14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS04910
gene id: 717605:THECO_RS04910
uniprot id: L0EBY5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS12550
gene id: 717605:THECO_RS12550
uniprot id: L0EGB3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

717605:THECO RS15055
gene id: 717605:THECO_RS15055
uniprot id: L0EHP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

717605:THECO RS09025
gene id: 717605:THECO_RS09025
uniprot id: L0EE67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

717605:THECO RS03110
gene id: 717605:THECO_RS03110
uniprot id: L0EB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS03515
gene id: 717605:THECO_RS03515
uniprot id: L0EBD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

717605:THECO RS01915
gene id: 717605:THECO_RS01915
uniprot id: L0EA94
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

717605:THECO RS10385
gene id: 717605:THECO_RS10385
uniprot id: L0EEM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

717605:THECO RS00900
gene id: 717605:THECO_RS00900
uniprot id: L0E9R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

717605:THECO RS04230
gene id: 717605:THECO_RS04230
uniprot id: L0EB85
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717605:THECO RS17190
gene id: 717605:THECO_RS17190
uniprot id: L0EIP1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS13840
gene id: 717605:THECO_RS13840
uniprot id: L0EGM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS02795
gene id: 717605:THECO_RS02795
uniprot id: L0EC74
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

717605:THECO RS12665
gene id: 717605:THECO_RS12665
uniprot id: L0EEI6
names: Similarity
messages: Belongs to the asparagine synthetase family.

717605:THECO RS10260
gene id: 717605:THECO_RS10260
uniprot id: L0EEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

717605:THECO RS18415
gene id: 717605:THECO_RS18415
uniprot id: L0EJ96
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

717605:THECO RS06025
gene id: 717605:THECO_RS06025
uniprot id: L0EC96
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

717605:THECO RS01385
gene id: 717605:THECO_RS01385
uniprot id: L0EBJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

717605:THECO RS18710
gene id: 717605:THECO_RS18710
uniprot id: L0EHZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

717605:THECO RS11240
gene id: 717605:THECO_RS11240
uniprot id: L0EFF8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

717605:THECO RS11930
gene id: 717605:THECO_RS11930
uniprot id: L0EHB9
names: Subcellular Location Annotation
messages: Cell membrane

717605:THECO RS04740
gene id: 717605:THECO_RS04740
uniprot id: L0EBV8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

717605:THECO RS11140
gene id: 717605:THECO_RS11140
uniprot id: L0EFE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09565
gene id: 717605:THECO_RS09565
uniprot id: L0EE46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

717605:THECO RS04305
gene id: 717605:THECO_RS04305
uniprot id: L0E9V8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS08980
gene id: 717605:THECO_RS08980
uniprot id: L0EDT4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

717605:THECO RS02145
gene id: 717605:THECO_RS02145
uniprot id: L0EBW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS14530
gene id: 717605:THECO_RS14530
uniprot id: L0EH86
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS09440
gene id: 717605:THECO_RS09440
uniprot id: L0EEL0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

717605:THECO RS05325
gene id: 717605:THECO_RS05325
uniprot id: L0EDN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

717605:THECO RS12675
gene id: 717605:THECO_RS12675
uniprot id: L0EHQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

717605:THECO RS16095
gene id: 717605:THECO_RS16095
uniprot id: L0EGI7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS13975
gene id: 717605:THECO_RS13975
uniprot id: L0EH56
names: Similarity
messages: Belongs to the peptidase S33 family.

717605:THECO RS08605
gene id: 717605:THECO_RS08605
uniprot id: L0ECB2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

717605:THECO RS05350
gene id: 717605:THECO_RS05350
uniprot id: L0EDP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

717605:THECO RS14365
gene id: 717605:THECO_RS14365
uniprot id: L0EFG7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

717605:THECO RS11050
gene id: 717605:THECO_RS11050
uniprot id: L0EGU7
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

717605:THECO RS05290
gene id: 717605:THECO_RS05290
uniprot id: L0ECA9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

717605:THECO RS08120
gene id: 717605:THECO_RS08120
uniprot id: L0EC07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

717605:THECO RS17765
gene id: 717605:THECO_RS17765
uniprot id: L0EJ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

717605:THECO RS17015
gene id: 717605:THECO_RS17015
uniprot id: L0EIM0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS20095
gene id: 717605:THECO_RS20095
uniprot id: L0ELD8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

717605:THECO RS18915
gene id: 717605:THECO_RS18915
uniprot id: L0EJR1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

717605:THECO RS16180
gene id: 717605:THECO_RS16180
uniprot id: L0EJK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10415
gene id: 717605:THECO_RS10415
uniprot id: L0EDA5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

717605:THECO RS10410
gene id: 717605:THECO_RS10410
uniprot id: L0EEN4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

717605:THECO RS18835
gene id: 717605:THECO_RS18835
uniprot id: L0EI16
names: Function
messages: Required for transformation and DNA binding.

717605:THECO RS12725
gene id: 717605:THECO_RS12725
uniprot id: L0EHR8
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

717605:THECO RS01320
gene id: 717605:THECO_RS01320
uniprot id: L0E882
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

717605:THECO RS18115
gene id: 717605:THECO_RS18115
uniprot id: L0EKF0
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

717605:THECO RS13635
gene id: 717605:THECO_RS13635
uniprot id: L0EF54
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS11235
gene id: 717605:THECO_RS11235
uniprot id: L0EGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

717605:THECO RS08385
gene id: 717605:THECO_RS08385
uniprot id: L0EE15
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

717605:THECO RS11310
gene id: 717605:THECO_RS11310
uniprot id: L0EFH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

717605:THECO RS09810
gene id: 717605:THECO_RS09810
uniprot id: L0EEA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

717605:THECO RS02240
gene id: 717605:THECO_RS02240
uniprot id: L0EAF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS16740
gene id: 717605:THECO_RS16740
uniprot id: L0EGU2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

717605:THECO RS10430
gene id: 717605:THECO_RS10430
uniprot id: L0EEY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

717605:THECO RS03850
gene id: 717605:THECO_RS03850
uniprot id: L0EBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

717605:THECO RS13280
gene id: 717605:THECO_RS13280
uniprot id: L0EGR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

717605:THECO RS08620
gene id: 717605:THECO_RS08620
uniprot id: L0EDZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS02780
gene id: 717605:THECO_RS02780
uniprot id: L0EAH7
names: Similarity
messages: Belongs to the Nth/MutY family.

717605:THECO RS16185
gene id: 717605:THECO_RS16185
uniprot id: L0EI67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS17040
gene id: 717605:THECO_RS17040
uniprot id: L0EIM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

717605:THECO RS18790
gene id: 717605:THECO_RS18790
uniprot id: L0EJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

717605:THECO RS10655
gene id: 717605:THECO_RS10655
uniprot id: L0EF37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

717605:THECO RS10665
gene id: 717605:THECO_RS10665
uniprot id: L0EDF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

717605:THECO RS03500
gene id: 717605:THECO_RS03500
uniprot id: L0EB58
names: Similarity
messages: Belongs to the arginase family.

717605:THECO RS17970
gene id: 717605:THECO_RS17970
uniprot id: L0EKC1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

717605:THECO RS18730
gene id: 717605:THECO_RS18730
uniprot id: L0EK29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

717605:THECO RS09135
gene id: 717605:THECO_RS09135
uniprot id: L0ECJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

717605:THECO RS07005
gene id: 717605:THECO_RS07005
uniprot id: L0EBF0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS11055
gene id: 717605:THECO_RS11055
uniprot id: L0EFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS08405
gene id: 717605:THECO_RS08405
uniprot id: L0EC85
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

717605:THECO RS10420
gene id: 717605:THECO_RS10420
uniprot id: L0EF51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

717605:THECO RS00475
gene id: 717605:THECO_RS00475
uniprot id: L0E9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS11380
gene id: 717605:THECO_RS11380
uniprot id: L0EH13
names: Subcellular Location Annotation
messages: Mitochondrion

717605:THECO RS01355
gene id: 717605:THECO_RS01355
uniprot id: L0EA50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

717605:THECO RS05405
gene id: 717605:THECO_RS05405
uniprot id: L0EC73
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

717605:THECO RS12325
gene id: 717605:THECO_RS12325
uniprot id: L0EEC0
names: Similarity
messages: Belongs to the UPF0735 family.

717605:THECO RS07430
gene id: 717605:THECO_RS07430
uniprot id: L0ED03
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS17265
gene id: 717605:THECO_RS17265
uniprot id: L0EIQ5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

717605:THECO RS15800
gene id: 717605:THECO_RS15800
uniprot id: L0EJD2
names: Similarity
messages: Belongs to the Dps family.

717605:THECO RS08005
gene id: 717605:THECO_RS08005
uniprot id: G4EC90
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS08515
gene id: 717605:THECO_RS08515
uniprot id: L0EFF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717605:THECO RS08990
gene id: 717605:THECO_RS08990
uniprot id: L0EEC6
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

717605:THECO RS04900
gene id: 717605:THECO_RS04900
uniprot id: U3GLD5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

717605:THECO RS12210
gene id: 717605:THECO_RS12210
uniprot id: L0EHH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS05935
gene id: 717605:THECO_RS05935
uniprot id: L0ECQ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

717605:THECO RS13575
gene id: 717605:THECO_RS13575
uniprot id: L0EGY1
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

717605:THECO RS12435
gene id: 717605:THECO_RS12435
uniprot id: L0EFS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

717605:THECO RS15350
gene id: 717605:THECO_RS15350
uniprot id: L0EHP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

717605:THECO RS01195
gene id: 717605:THECO_RS01195
uniprot id: L0E861
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

717605:THECO RS13075
gene id: 717605:THECO_RS13075
uniprot id: L0EHY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS01270
gene id: 717605:THECO_RS01270
uniprot id: L0E874
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

717605:THECO RS12235
gene id: 717605:THECO_RS12235
uniprot id: L0EHH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

717605:THECO RS16975
gene id: 717605:THECO_RS16975
uniprot id: L0EGY7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

717605:THECO RS09190
gene id: 717605:THECO_RS09190
uniprot id: L0EFT1
names: Similarity
messages: Belongs to the MecA family.

717605:THECO RS17935
gene id: 717605:THECO_RS17935
uniprot id: L0EHH7
names: Similarity
messages: Belongs to the AHA1 family.

717605:THECO RS01040
gene id: 717605:THECO_RS01040
uniprot id: L0E9U7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

717605:THECO RS16850
gene id: 717605:THECO_RS16850
uniprot id: L0EI70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

717605:THECO RS03495
gene id: 717605:THECO_RS03495
uniprot id: L0ECP6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS07785
gene id: 717605:THECO_RS07785
uniprot id: L0EDM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

717605:THECO RS12200
gene id: 717605:THECO_RS12200
uniprot id: L0EE95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS08430
gene id: 717605:THECO_RS08430
uniprot id: L0EC88
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

717605:THECO RS10300
gene id: 717605:THECO_RS10300
uniprot id: L0EGE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

717605:THECO RS06630
gene id: 717605:THECO_RS06630
uniprot id: L0ED19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09605
gene id: 717605:THECO_RS09605
uniprot id: L0EG15
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

717605:THECO RS18280
gene id: 717605:THECO_RS18280
uniprot id: L0EKH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

717605:THECO RS01680
gene id: 717605:THECO_RS01680
uniprot id: L0E8E0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS10030
gene id: 717605:THECO_RS10030
uniprot id: L0EEF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

717605:THECO RS12615
gene id: 717605:THECO_RS12615
uniprot id: L0EEH6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS18995
gene id: 717605:THECO_RS18995
uniprot id: L0EJS2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

717605:THECO RS06925
gene id: 717605:THECO_RS06925
uniprot id: L0ECP8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS09985
gene id: 717605:THECO_RS09985
uniprot id: L0ED21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

717605:THECO RS00300
gene id: 717605:THECO_RS00300
uniprot id: L0E9I2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS14035
gene id: 717605:THECO_RS14035
uniprot id: L0EH12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12350
gene id: 717605:THECO_RS12350
uniprot id: L0EEC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

717605:THECO RS12515
gene id: 717605:THECO_RS12515
uniprot id: L0EFU5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

717605:THECO RS03405
gene id: 717605:THECO_RS03405
uniprot id: L0E9E2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS04160
gene id: 717605:THECO_RS04160
uniprot id: L0E9S8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS18880
gene id: 717605:THECO_RS18880
uniprot id: L0EK57
names: Similarity
messages: Belongs to the UPF0340 family.

717605:THECO RS07620
gene id: 717605:THECO_RS07620
uniprot id: L0EDD5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

717605:THECO RS12020
gene id: 717605:THECO_RS12020
uniprot id: L0EE55
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS06305
gene id: 717605:THECO_RS06305
uniprot id: L0ECD8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS16265
gene id: 717605:THECO_RS16265
uniprot id: L0EHY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS01500
gene id: 717605:THECO_RS01500
uniprot id: L0E8C0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

717605:THECO RS18885
gene id: 717605:THECO_RS18885
uniprot id: L0EI23
names: Similarity
messages: Belongs to the LacAB/RpiB family.

717605:THECO RS16320
gene id: 717605:THECO_RS16320
uniprot id: L0EI93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09595
gene id: 717605:THECO_RS09595
uniprot id: L0ECU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

717605:THECO RS18815
gene id: 717605:THECO_RS18815
uniprot id: L0EJP8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

717605:THECO RS02745
gene id: 717605:THECO_RS02745
uniprot id: L0EC63
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

717605:THECO RS09765
gene id: 717605:THECO_RS09765
uniprot id: L0EE91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

717605:THECO RS12230
gene id: 717605:THECO_RS12230
uniprot id: L0EG55
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS18890
gene id: 717605:THECO_RS18890
uniprot id: L0EJQ7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

717605:THECO RS02620
gene id: 717605:THECO_RS02620
uniprot id: L0EC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10620
gene id: 717605:THECO_RS10620
uniprot id: L0EF89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

717605:THECO RS02970
gene id: 717605:THECO_RS02970
uniprot id: L0EAW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

717605:THECO RS13505
gene id: 717605:THECO_RS13505
uniprot id: L0EGW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

717605:THECO RS13045
gene id: 717605:THECO_RS13045
uniprot id: L0EER8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

717605:THECO RS13560
gene id: 717605:THECO_RS13560
uniprot id: L0EGS3
names: Similarity
messages: Belongs to the GerABKA family.

717605:THECO RS02285
gene id: 717605:THECO_RS02285
uniprot id: L0EAL2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS16135
gene id: 717605:THECO_RS16135
uniprot id: L0EI59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS13750
gene id: 717605:THECO_RS13750
uniprot id: L0EIE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10120
gene id: 717605:THECO_RS10120
uniprot id: L0EGB5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

717605:THECO RS08350
gene id: 717605:THECO_RS08350
uniprot id: L0EDI3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

717605:THECO RS14960
gene id: 717605:THECO_RS14960
uniprot id: L0EIZ8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

717605:THECO RS06945
gene id: 717605:THECO_RS06945
uniprot id: L0ED17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. CshA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
messages: Oligomerizes, may be a member of the RNA degradosome.

717605:THECO RS04935
gene id: 717605:THECO_RS04935
uniprot id: L0EBZ0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

717605:THECO RS01395
gene id: 717605:THECO_RS01395
uniprot id: L0E9R2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

717605:THECO RS06675
gene id: 717605:THECO_RS06675
uniprot id: L0ECV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS03535
gene id: 717605:THECO_RS03535
uniprot id: L0EAV8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

717605:THECO RS11350
gene id: 717605:THECO_RS11350
uniprot id: L0EFP0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

717605:THECO RS06350
gene id: 717605:THECO_RS06350
uniprot id: L0ECQ3
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

717605:THECO RS13680
gene id: 717605:THECO_RS13680
uniprot id: L0EGU4
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

717605:THECO RS17195
gene id: 717605:THECO_RS17195
uniprot id: L0EIC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS05490
gene id: 717605:THECO_RS05490
uniprot id: L0EAL6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

717605:THECO RS10775
gene id: 717605:THECO_RS10775
uniprot id: L0EGQ1
names: Similarity
messages: Belongs to the peptidase M29 family.

717605:THECO RS17415
gene id: 717605:THECO_RS17415
uniprot id: L0EIG8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS10085
gene id: 717605:THECO_RS10085
uniprot id: L0ED41
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

717605:THECO RS11475
gene id: 717605:THECO_RS11475
uniprot id: L0EFR4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

717605:THECO RS10470
gene id: 717605:THECO_RS10470
uniprot id: L0EF59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

717605:THECO RS05515
gene id: 717605:THECO_RS05515
uniprot id: L0EAL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

717605:THECO RS11940
gene id: 717605:THECO_RS11940
uniprot id: L0EFG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS03955
gene id: 717605:THECO_RS03955
uniprot id: L0ECY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS01365
gene id: 717605:THECO_RS01365
uniprot id: L0EA08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

717605:THECO RS13065
gene id: 717605:THECO_RS13065
uniprot id: L0EES3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS12405
gene id: 717605:THECO_RS12405
uniprot id: L0EG89
names: Similarity
messages: Belongs to the UPF0758 family.

717605:THECO RS01485
gene id: 717605:THECO_RS01485
uniprot id: L0EBL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

717605:THECO RS11980
gene id: 717605:THECO_RS11980
uniprot id: L0EHD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

717605:THECO RS08180
gene id: 717605:THECO_RS08180
uniprot id: L0EF79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS15030
gene id: 717605:THECO_RS15030
uniprot id: L0EHP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

717605:THECO RS02250
gene id: 717605:THECO_RS02250
uniprot id: L0E8Q4
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

717605:THECO RS09615
gene id: 717605:THECO_RS09615
uniprot id: L0EE57
names: Similarity
messages: Belongs to the asp23 family.

717605:THECO RS08215
gene id: 717605:THECO_RS08215
uniprot id: L0EDQ4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

717605:THECO RS08480
gene id: 717605:THECO_RS08480
uniprot id: L0EC97
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

717605:THECO RS08895
gene id: 717605:THECO_RS08895
uniprot id: L0EEA6
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS09325
gene id: 717605:THECO_RS09325
uniprot id: L0ECN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

717605:THECO RS07420
gene id: 717605:THECO_RS07420
uniprot id: L0EEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS15035
gene id: 717605:THECO_RS15035
uniprot id: L0EJ14
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

717605:THECO RS18875
gene id: 717605:THECO_RS18875
uniprot id: L0EJH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS09855
gene id: 717605:THECO_RS09855
uniprot id: L0EEN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

717605:THECO RS13145
gene id: 717605:THECO_RS13145
uniprot id: L0EHZ8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS09735
gene id: 717605:THECO_RS09735
uniprot id: L0EEK8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

717605:THECO RS19275
gene id: 717605:THECO_RS19275
uniprot id: L0EL03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

717605:THECO RS06195
gene id: 717605:THECO_RS06195
uniprot id: L0ECM4
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS04775
gene id: 717605:THECO_RS04775
uniprot id: L0EC13
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

717605:THECO RS18690
gene id: 717605:THECO_RS18690
uniprot id: L0EJM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS13795
gene id: 717605:THECO_RS13795
uniprot id: L0EF76
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS13740
gene id: 717605:THECO_RS13740
uniprot id: L0EF70
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

717605:THECO RS09105
gene id: 717605:THECO_RS09105
uniprot id: L0EDV3
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

717605:THECO RS01875
gene id: 717605:THECO_RS01875
uniprot id: L0EAD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

717605:THECO RS09225
gene id: 717605:THECO_RS09225
uniprot id: L0EDX3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

717605:THECO RS16205
gene id: 717605:THECO_RS16205
uniprot id: L0EJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS05230
gene id: 717605:THECO_RS05230
uniprot id: L0EBT7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS17895
gene id: 717605:THECO_RS17895
uniprot id: L0EJ22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

717605:THECO RS06965
gene id: 717605:THECO_RS06965
uniprot id: L0EEL1
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS09010
gene id: 717605:THECO_RS09010
uniprot id: L0ECH0
names: Similarity
messages: Belongs to the TrpF family.

717605:THECO RS18300
gene id: 717605:THECO_RS18300
uniprot id: L0EJF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

717605:THECO RS00325
gene id: 717605:THECO_RS00325
uniprot id: L0E9J9
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS13105
gene id: 717605:THECO_RS13105
uniprot id: L0EG70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

717605:THECO RS14845
gene id: 717605:THECO_RS14845
uniprot id: L0EH44
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

717605:THECO RS03030
gene id: 717605:THECO_RS03030
uniprot id: L0E988
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

717605:THECO RS17850
gene id: 717605:THECO_RS17850
uniprot id: L0EIP7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS14790
gene id: 717605:THECO_RS14790
uniprot id: L0EHD7
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

717605:THECO RS06835
gene id: 717605:THECO_RS06835
uniprot id: L0ED59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

717605:THECO RS08190
gene id: 717605:THECO_RS08190
uniprot id: L0EDP9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

717605:THECO RS07705
gene id: 717605:THECO_RS07705
uniprot id: L0EBS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

717605:THECO RS00530
gene id: 717605:THECO_RS00530
uniprot id: L0E7V9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

717605:THECO RS07070
gene id: 717605:THECO_RS07070
uniprot id: L0ECT1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS00760
gene id: 717605:THECO_RS00760
uniprot id: L0E9T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

717605:THECO RS02520
gene id: 717605:THECO_RS02520
uniprot id: L0EC24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

717605:THECO RS02660
gene id: 717605:THECO_RS02660
uniprot id: L0E8Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS15585
gene id: 717605:THECO_RS15585
uniprot id: L0EHJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS18330
gene id: 717605:THECO_RS18330
uniprot id: L0EKI7
names: Similarity
messages: Belongs to the ParB family.

717605:THECO RS09875
gene id: 717605:THECO_RS09875
uniprot id: L0EG67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

717605:THECO RS08470
gene id: 717605:THECO_RS08470
uniprot id: L0EDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

717605:THECO RS06395
gene id: 717605:THECO_RS06395
uniprot id: L0ECY3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

717605:THECO RS17795
gene id: 717605:THECO_RS17795
uniprot id: L0EK90
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

717605:THECO RS02595
gene id: 717605:THECO_RS02595
uniprot id: L0EAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

717605:THECO RS13315
gene id: 717605:THECO_RS13315
uniprot id: L0EGN4
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

717605:THECO RS20695
gene id: 717605:THECO_RS20695
uniprot id: L0EHS8
names: Similarity
messages: Belongs to the PspA/IM30 family.

717605:THECO RS03075
gene id: 717605:THECO_RS03075
uniprot id: L0EAP2
names: Similarity
messages: Belongs to the UxaA family.

717605:THECO RS01450
gene id: 717605:THECO_RS01450
uniprot id: L0E8B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

717605:THECO RS02880
gene id: 717605:THECO_RS02880
uniprot id: L0EAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS00920
gene id: 717605:THECO_RS00920
uniprot id: L0E9S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

717605:THECO RS18450
gene id: 717605:THECO_RS18450
uniprot id: L0EHS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

717605:THECO RS00220
gene id: 717605:THECO_RS00220
uniprot id: L0E7P3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

717605:THECO RS09485
gene id: 717605:THECO_RS09485
uniprot id: L0EEM0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717605:THECO RS13440
gene id: 717605:THECO_RS13440
uniprot id: L0EGQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS00735
gene id: 717605:THECO_RS00735
uniprot id: L0E9T0
names: Similarity
messages: Belongs to the FlgM family.

717605:THECO RS11590
gene id: 717605:THECO_RS11590
uniprot id: L0EFA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

717605:THECO RS04140
gene id: 717605:THECO_RS04140
uniprot id: L0EBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

717605:THECO RS15880
gene id: 717605:THECO_RS15880
uniprot id: L0EI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS15025
gene id: 717605:THECO_RS15025
uniprot id: L0EFU9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

717605:THECO RS12390
gene id: 717605:THECO_RS12390
uniprot id: L0EG35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

717605:THECO RS19855
gene id: 717605:THECO_RS19855
uniprot id: L0EKK5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS16565
gene id: 717605:THECO_RS16565
uniprot id: L0EIK9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

717605:THECO RS00665
gene id: 717605:THECO_RS00665
uniprot id: L0EB57
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

717605:THECO RS00780
gene id: 717605:THECO_RS00780
uniprot id: L0E7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

717605:THECO RS08140
gene id: 717605:THECO_RS08140
uniprot id: L0EDE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS13640
gene id: 717605:THECO_RS13640
uniprot id: L0EGZ2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS22355
gene id: 717605:THECO_RS22355
uniprot id: L0EGL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS06900
gene id: 717605:THECO_RS06900
uniprot id: L0ECP2
names: Subcellular Location Annotation
messages: Cytoplasm

717605:THECO RS00905
gene id: 717605:THECO_RS00905
uniprot id: L0E9I5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

717605:THECO RS13195
gene id: 717605:THECO_RS13195
uniprot id: L0EGI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS14350
gene id: 717605:THECO_RS14350
uniprot id: L0EIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09510
gene id: 717605:THECO_RS09510
uniprot id: L0EEG5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

717605:THECO RS18315
gene id: 717605:THECO_RS18315
uniprot id: L0EIY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

717605:THECO RS17865
gene id: 717605:THECO_RS17865
uniprot id: L0EKA3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

717605:THECO RS14025
gene id: 717605:THECO_RS14025
uniprot id: L0EH65
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01325
gene id: 717605:THECO_RS01325
uniprot id: L0EA45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

717605:THECO RS00205
gene id: 717605:THECO_RS00205
uniprot id: L0EAW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS17030
gene id: 717605:THECO_RS17030
uniprot id: L0EIU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

717605:THECO RS01200
gene id: 717605:THECO_RS01200
uniprot id: L0EA20
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

717605:THECO RS02185
gene id: 717605:THECO_RS02185
uniprot id: L0E8P1
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS14545
gene id: 717605:THECO_RS14545
uniprot id: L0EHF1
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS12215
gene id: 717605:THECO_RS12215
uniprot id: L0EFZ9
names: Similarity
messages: Belongs to the RecJ family.

717605:THECO RS14640
gene id: 717605:THECO_RS14640
uniprot id: L0EFM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

717605:THECO RS08255
gene id: 717605:THECO_RS08255
uniprot id: L0EDX6
names: Similarity
messages: Belongs to the peptidase C40 family.

717605:THECO RS12330
gene id: 717605:THECO_RS12330
uniprot id: L0EG74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

717605:THECO RS16705
gene id: 717605:THECO_RS16705
uniprot id: L0EIG0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

717605:THECO RS06660
gene id: 717605:THECO_RS06660
uniprot id: L0EB79
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS02150
gene id: 717605:THECO_RS02150
uniprot id: L0EAE0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

717605:THECO RS16535
gene id: 717605:THECO_RS16535
uniprot id: L0EGQ3
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS16915
gene id: 717605:THECO_RS16915
uniprot id: L0EJV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

717605:THECO RS15525
gene id: 717605:THECO_RS15525
uniprot id: L0EHX8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS10395
gene id: 717605:THECO_RS10395
uniprot id: L0EF46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

717605:THECO RS10170
gene id: 717605:THECO_RS10170
uniprot id: U3GLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

717605:THECO RS12250
gene id: 717605:THECO_RS12250
uniprot id: L0EEA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

717605:THECO RS12205
gene id: 717605:THECO_RS12205
uniprot id: L0EG50
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

717605:THECO RS13150
gene id: 717605:THECO_RS13150
uniprot id: L0EGH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717605:THECO RS02715
gene id: 717605:THECO_RS02715
uniprot id: L0EAU9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS03680
gene id: 717605:THECO_RS03680
uniprot id: L0EAY4
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01390
gene id: 717605:THECO_RS01390
uniprot id: L0EA13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

717605:THECO RS17230
gene id: 717605:THECO_RS17230
uniprot id: L0EIX1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

717605:THECO RS01660
gene id: 717605:THECO_RS01660
uniprot id: L0EA97
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

717605:THECO RS00465
gene id: 717605:THECO_RS00465
uniprot id: L0E9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

717605:THECO RS06560
gene id: 717605:THECO_RS06560
uniprot id: L0ECT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS11015
gene id: 717605:THECO_RS11015
uniprot id: L0EF01
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS08885
gene id: 717605:THECO_RS08885
uniprot id: L0ECE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

717605:THECO RS14690
gene id: 717605:THECO_RS14690
uniprot id: L0EH17
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

717605:THECO RS08020
gene id: 717605:THECO_RS08020
uniprot id: L0EDB8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS07335
gene id: 717605:THECO_RS07335
uniprot id: L0EET3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

717605:THECO RS06060
gene id: 717605:THECO_RS06060
uniprot id: L0ECS2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

717605:THECO RS10660
gene id: 717605:THECO_RS10660
uniprot id: L0EET5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS13695
gene id: 717605:THECO_RS13695
uniprot id: L0EH02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12185
gene id: 717605:THECO_RS12185
uniprot id: L0EG45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS05650
gene id: 717605:THECO_RS05650
uniprot id: L0EAR7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

717605:THECO RS10265
gene id: 717605:THECO_RS10265
uniprot id: L0ED77
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

717605:THECO RS20720
gene id: 717605:THECO_RS20720
uniprot id: L0EIB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

717605:THECO RS04885
gene id: 717605:THECO_RS04885
uniprot id: L0EBY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

717605:THECO RS11320
gene id: 717605:THECO_RS11320
uniprot id: L0EDT5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS05740
gene id: 717605:THECO_RS05740
uniprot id: L0EAT1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

717605:THECO RS02605
gene id: 717605:THECO_RS02605
uniprot id: L0EAM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

717605:THECO RS11525
gene id: 717605:THECO_RS11525
uniprot id: L0EH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

717605:THECO RS02630
gene id: 717605:THECO_RS02630
uniprot id: L0EAE7
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

717605:THECO RS12375
gene id: 717605:THECO_RS12375
uniprot id: L0EED0
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS13535
gene id: 717605:THECO_RS13535
uniprot id: L0EGR9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

717605:THECO RS12940
gene id: 717605:THECO_RS12940
uniprot id: L0EEP6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

717605:THECO RS18900
gene id: 717605:THECO_RS18900
uniprot id: L0EJH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

717605:THECO RS06510
gene id: 717605:THECO_RS06510
uniprot id: L0ECT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

717605:THECO RS01280
gene id: 717605:THECO_RS01280
uniprot id: L0EBH1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

717605:THECO RS12285
gene id: 717605:THECO_RS12285
uniprot id: L0EHI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

717605:THECO RS11070
gene id: 717605:THECO_RS11070
uniprot id: L0EFI6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS05620
gene id: 717605:THECO_RS05620
uniprot id: L0EC34
names: Similarity
messages: Belongs to the polysaccharide synthase family.

717605:THECO RS09600
gene id: 717605:THECO_RS09600
uniprot id: L0EEP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

717605:THECO RS01205
gene id: 717605:THECO_RS01205
uniprot id: L0EBF7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

717605:THECO RS03930
gene id: 717605:THECO_RS03930
uniprot id: L0ECY0
names: Similarity
messages: Belongs to the DinB family.

717605:THECO RS02980
gene id: 717605:THECO_RS02980
uniprot id: L0E971
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

717605:THECO RS11175
gene id: 717605:THECO_RS11175
uniprot id: L0EDR3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

717605:THECO RS01150
gene id: 717605:THECO_RS01150
uniprot id: L0EA10
names: Similarity
messages: Belongs to the PspA/IM30 family.

717605:THECO RS11275
gene id: 717605:THECO_RS11275
uniprot id: L0EFM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

717605:THECO RS13375
gene id: 717605:THECO_RS13375
uniprot id: L0EF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS08600
gene id: 717605:THECO_RS08600
uniprot id: L0EDM2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

717605:THECO RS00255
gene id: 717605:THECO_RS00255
uniprot id: L0EAX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS09880
gene id: 717605:THECO_RS09880
uniprot id: L0EEN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

717605:THECO RS17450
gene id: 717605:THECO_RS17450
uniprot id: L0EJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS15315
gene id: 717605:THECO_RS15315
uniprot id: L0EHT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS01405
gene id: 717605:THECO_RS01405
uniprot id: L0EA61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

717605:THECO RS01455
gene id: 717605:THECO_RS01455
uniprot id: L0EA71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

717605:THECO RS01445
gene id: 717605:THECO_RS01445
uniprot id: L0E9S4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

717605:THECO RS14795
gene id: 717605:THECO_RS14795
uniprot id: L0EH34
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

717605:THECO RS17075
gene id: 717605:THECO_RS17075
uniprot id: L0EH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

717605:THECO RS06970
gene id: 717605:THECO_RS06970
uniprot id: L0ED22
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS08635
gene id: 717605:THECO_RS08635
uniprot id: L0EE61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

717605:THECO RS06720
gene id: 717605:THECO_RS06720
uniprot id: L0EEG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacteriophage holin family. Cp-1 holin subfamily.
messages: Membrane

717605:THECO RS18795
gene id: 717605:THECO_RS18795
uniprot id: L0EKT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

717605:THECO RS10055
gene id: 717605:THECO_RS10055
uniprot id: L0EEF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS01330
gene id: 717605:THECO_RS01330
uniprot id: L0EBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

717605:THECO RS16905
gene id: 717605:THECO_RS16905
uniprot id: L0EGX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

717605:THECO RS00090
gene id: 717605:THECO_RS00090
uniprot id: L0E994
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

717605:THECO RS10350
gene id: 717605:THECO_RS10350
uniprot id: L0EGF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

717605:THECO RS18090
gene id: 717605:THECO_RS18090
uniprot id: L0EKE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS00590
gene id: 717605:THECO_RS00590
uniprot id: L0EB44
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS11405
gene id: 717605:THECO_RS11405
uniprot id: L0EH14
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

717605:THECO RS01275
gene id: 717605:THECO_RS01275
uniprot id: L0EA34
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

717605:THECO RS04330
gene id: 717605:THECO_RS04330
uniprot id: L0E9W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

717605:THECO RS06855
gene id: 717605:THECO_RS06855
uniprot id: L0EBB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

717605:THECO RS11245
gene id: 717605:THECO_RS11245
uniprot id: L0EF49
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

717605:THECO RS10615
gene id: 717605:THECO_RS10615
uniprot id: L0EDE7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS03775
gene id: 717605:THECO_RS03775
uniprot id: L0EBB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

717605:THECO RS15045
gene id: 717605:THECO_RS15045
uniprot id: L0EH85
names: Similarity
messages: Belongs to the SAICAR synthetase family.

717605:THECO RS09885
gene id: 717605:THECO_RS09885
uniprot id: L0EEB9
names: Similarity
messages: Belongs to the UPF0234 family.

717605:THECO RS10280
gene id: 717605:THECO_RS10280
uniprot id: L0EEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

717605:THECO RS15935
gene id: 717605:THECO_RS15935
uniprot id: L0EJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

717605:THECO RS17200
gene id: 717605:THECO_RS17200
uniprot id: L0EH28
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

717605:THECO RS01350
gene id: 717605:THECO_RS01350
uniprot id: L0E887
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

717605:THECO RS10405
gene id: 717605:THECO_RS10405
uniprot id: L0EEY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

717605:THECO RS09460
gene id: 717605:THECO_RS09460
uniprot id: L0ECQ9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

717605:THECO RS18760
gene id: 717605:THECO_RS18760
uniprot id: L0EI03
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS14725
gene id: 717605:THECO_RS14725
uniprot id: L0EHI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

717605:THECO RS14235
gene id: 717605:THECO_RS14235
uniprot id: L0EH93
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

717605:THECO RS10425
gene id: 717605:THECO_RS10425
uniprot id: L0EGG7
names: Similarity
messages: Belongs to the fabD family.

717605:THECO RS02265
gene id: 717605:THECO_RS02265
uniprot id: L0EAF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS18135
gene id: 717605:THECO_RS18135
uniprot id: L0EJD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

717605:THECO RS14970
gene id: 717605:THECO_RS14970
uniprot id: L0EH71
names: Similarity
messages: Belongs to the ComB family.

717605:THECO RS18335
gene id: 717605:THECO_RS18335
uniprot id: L0EJ86
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

717605:THECO RS11445
gene id: 717605:THECO_RS11445
uniprot id: L0EDV5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

717605:THECO RS12500
gene id: 717605:THECO_RS12500
uniprot id: L0EGA5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

717605:THECO RS16945
gene id: 717605:THECO_RS16945
uniprot id: L0EIK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

717605:THECO RS12110
gene id: 717605:THECO_RS12110
uniprot id: L0EG33
names: Similarity
messages: Belongs to the UPF0473 family.

717605:THECO RS16910
gene id: 717605:THECO_RS16910
uniprot id: L0EIS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

717605:THECO RS10755
gene id: 717605:THECO_RS10755
uniprot id: L0EF77
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS05700
gene id: 717605:THECO_RS05700
uniprot id: L0EDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

717605:THECO RS07495
gene id: 717605:THECO_RS07495
uniprot id: L0EDB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

717605:THECO RS12855
gene id: 717605:THECO_RS12855
uniprot id: L0EGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

717605:THECO RS09625
gene id: 717605:THECO_RS09625
uniprot id: L0EEP7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

717605:THECO RS14805
gene id: 717605:THECO_RS14805
uniprot id: L0EHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

717605:THECO RS08985
gene id: 717605:THECO_RS08985
uniprot id: L0ECG6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717605:THECO RS18295
gene id: 717605:THECO_RS18295
uniprot id: L0EHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

717605:THECO RS16625
gene id: 717605:THECO_RS16625
uniprot id: L0EIE8
names: Similarity
messages: Belongs to the AHA1 family.

717605:THECO RS20405
gene id: 717605:THECO_RS20405
uniprot id: L0EBX0
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01285
gene id: 717605:THECO_RS01285
uniprot id: L0E9Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

717605:THECO RS19105
gene id: 717605:THECO_RS19105
uniprot id: L0EI51
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

717605:THECO RS09690
gene id: 717605:THECO_RS09690
uniprot id: L0EE75
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

717605:THECO RS03225
gene id: 717605:THECO_RS03225
uniprot id: L0E9B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

717605:THECO RS10705
gene id: 717605:THECO_RS10705
uniprot id: L0EF47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS14030
gene id: 717605:THECO_RS14030
uniprot id: L0EIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

717605:THECO RS00850
gene id: 717605:THECO_RS00850
uniprot id: L0E9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

717605:THECO RS14765
gene id: 717605:THECO_RS14765
uniprot id: L0EHD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

717605:THECO RS12530
gene id: 717605:THECO_RS12530
uniprot id: L0EHN9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

717605:THECO RS18930
gene id: 717605:THECO_RS18930
uniprot id: L0EK66
names: Similarity
messages: Belongs to the thioredoxin family.

717605:THECO RS20665
gene id: 717605:THECO_RS20665
uniprot id: L0EHH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS18075
gene id: 717605:THECO_RS18075
uniprot id: L0EIU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

717605:THECO RS14475
gene id: 717605:THECO_RS14475
uniprot id: L0EHD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12190
gene id: 717605:THECO_RS12190
uniprot id: L0EHG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS10560
gene id: 717605:THECO_RS10560
uniprot id: L0EER4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

717605:THECO RS04605
gene id: 717605:THECO_RS04605
uniprot id: L0EA24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

717605:THECO RS08700
gene id: 717605:THECO_RS08700
uniprot id: L0EE06
names: Similarity
messages: Belongs to the CapA family.

717605:THECO RS18110
gene id: 717605:THECO_RS18110
uniprot id: L0EJC7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

717605:THECO RS09055
gene id: 717605:THECO_RS09055
uniprot id: L0ECH8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

717605:THECO RS11685
gene id: 717605:THECO_RS11685
uniprot id: L0EFB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

717605:THECO RS05615
gene id: 717605:THECO_RS05615
uniprot id: L0ECD4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

717605:THECO RS11700
gene id: 717605:THECO_RS11700
uniprot id: L0EFQ6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

717605:THECO RS02995
gene id: 717605:THECO_RS02995
uniprot id: L0EAX1
names: Similarity
messages: Belongs to the IMPACT family.

717605:THECO RS08040
gene id: 717605:THECO_RS08040
uniprot id: L0EDL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

717605:THECO RS06465
gene id: 717605:THECO_RS06465
uniprot id: L0EB46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

717605:THECO RS03570
gene id: 717605:THECO_RS03570
uniprot id: L0ECR1
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

717605:THECO RS11665
gene id: 717605:THECO_RS11665
uniprot id: L0EDY6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

717605:THECO RS07790
gene id: 717605:THECO_RS07790
uniprot id: L0EF05
names: Similarity
messages: Belongs to the DinB family.

717605:THECO RS08685
gene id: 717605:THECO_RS08685
uniprot id: L0ECC2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717605:THECO RS07575
gene id: 717605:THECO_RS07575
uniprot id: L0ED26
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

717605:THECO RS18615
gene id: 717605:THECO_RS18615
uniprot id: L0EJL5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

717605:THECO RS11640
gene id: 717605:THECO_RS11640
uniprot id: L0EDY4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

717605:THECO RS18095
gene id: 717605:THECO_RS18095
uniprot id: L0EJ55
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

717605:THECO RS11440
gene id: 717605:THECO_RS11440
uniprot id: L0EF80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

717605:THECO RS13380
gene id: 717605:THECO_RS13380
uniprot id: L0EGU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS14605
gene id: 717605:THECO_RS14605
uniprot id: L0EH99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

717605:THECO RS02600
gene id: 717605:THECO_RS02600
uniprot id: L0EC36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS14745
gene id: 717605:THECO_RS14745
uniprot id: L0EFP2
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

717605:THECO RS13080
gene id: 717605:THECO_RS13080
uniprot id: L0EGF9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

717605:THECO RS01465
gene id: 717605:THECO_RS01465
uniprot id: L0EA27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

717605:THECO RS11985
gene id: 717605:THECO_RS11985
uniprot id: L0EFV8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

717605:THECO RS14925
gene id: 717605:THECO_RS14925
uniprot id: L0EFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12475
gene id: 717605:THECO_RS12475
uniprot id: L0EHM9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

717605:THECO RS15090
gene id: 717605:THECO_RS15090
uniprot id: L0EJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS00895
gene id: 717605:THECO_RS00895
uniprot id: L0EBA0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

717605:THECO RS00065
gene id: 717605:THECO_RS00065
uniprot id: L0E931
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01950
gene id: 717605:THECO_RS01950
uniprot id: L0EA11
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

717605:THECO RS12275
gene id: 717605:THECO_RS12275
uniprot id: L0EEB0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

717605:THECO RS13865
gene id: 717605:THECO_RS13865
uniprot id: L0EGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS06825
gene id: 717605:THECO_RS06825
uniprot id: L0ECM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS10535
gene id: 717605:THECO_RS10535
uniprot id: L0EEQ9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

717605:THECO RS00750
gene id: 717605:THECO_RS00750
uniprot id: L0E9G1
names: Similarity
messages: Belongs to the bacterial flagellin family.

717605:THECO RS03180
gene id: 717605:THECO_RS03180
uniprot id: L0E9A8
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

717605:THECO RS05260
gene id: 717605:THECO_RS05260
uniprot id: L0EBU2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

717605:THECO RS10790
gene id: 717605:THECO_RS10790
uniprot id: L0EDK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

717605:THECO RS04335
gene id: 717605:THECO_RS04335
uniprot id: L0EBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

717605:THECO RS00765
gene id: 717605:THECO_RS00765
uniprot id: L0EB78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

717605:THECO RS12305
gene id: 717605:THECO_RS12305
uniprot id: L0EG69
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

717605:THECO RS08095
gene id: 717605:THECO_RS08095
uniprot id: L0EDD3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

717605:THECO RS14800
gene id: 717605:THECO_RS14800
uniprot id: L0EFQ2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

717605:THECO RS00070
gene id: 717605:THECO_RS00070
uniprot id: L0E7L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12320
gene id: 717605:THECO_RS12320
uniprot id: L0EFP9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

717605:THECO RS12545
gene id: 717605:THECO_RS12545
uniprot id: L0EEG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

717605:THECO RS00295
gene id: 717605:THECO_RS00295
uniprot id: L0E7Q7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS15855
gene id: 717605:THECO_RS15855
uniprot id: L0EHZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

717605:THECO RS02735
gene id: 717605:THECO_RS02735
uniprot id: L0E905
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

717605:THECO RS17180
gene id: 717605:THECO_RS17180
uniprot id: L0EIW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

717605:THECO RS02575
gene id: 717605:THECO_RS02575
uniprot id: L0EC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS04465
gene id: 717605:THECO_RS04465
uniprot id: L0E9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS19210
gene id: 717605:THECO_RS19210
uniprot id: L0EI65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS13690
gene id: 717605:THECO_RS13690
uniprot id: L0EF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS15910
gene id: 717605:THECO_RS15910
uniprot id: L0EI22
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS12520
gene id: 717605:THECO_RS12520
uniprot id: L0EEG3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

717605:THECO RS00110
gene id: 717605:THECO_RS00110
uniprot id: L0EAU6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS15600
gene id: 717605:THECO_RS15600
uniprot id: L0EJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18275
gene id: 717605:THECO_RS18275
uniprot id: L0EJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

717605:THECO RS10795
gene id: 717605:THECO_RS10795
uniprot id: L0EFD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS12125
gene id: 717605:THECO_RS12125
uniprot id: L0EFK5
names: Similarity
messages: Belongs to the UPF0297 family.

717605:THECO RS10565
gene id: 717605:THECO_RS10565
uniprot id: L0EDD8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

717605:THECO RS12370
gene id: 717605:THECO_RS12370
uniprot id: L0EFR0
names: Similarity
messages: Belongs to the EamA transporter family.

717605:THECO RS07290
gene id: 717605:THECO_RS07290
uniprot id: L0ED82
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

717605:THECO RS04825
gene id: 717605:THECO_RS04825
uniprot id: L0EC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09145
gene id: 717605:THECO_RS09145
uniprot id: L0EFS1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

717605:THECO RS10255
gene id: 717605:THECO_RS10255
uniprot id: L0EEV8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

717605:THECO RS12400
gene id: 717605:THECO_RS12400
uniprot id: L0EED6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

717605:THECO RS09760
gene id: 717605:THECO_RS09760
uniprot id: L0EEL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS10730
gene id: 717605:THECO_RS10730
uniprot id: L0EF65
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

717605:THECO RS12040
gene id: 717605:THECO_RS12040
uniprot id: L0EFI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

717605:THECO RS05185
gene id: 717605:THECO_RS05185
uniprot id: L0EAF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS01520
gene id: 717605:THECO_RS01520
uniprot id: L0E9U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

717605:THECO RS01310
gene id: 717605:THECO_RS01310
uniprot id: L0E9Z8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

717605:THECO RS05010
gene id: 717605:THECO_RS05010
uniprot id: L0EC06
names: Similarity
messages: Belongs to the glutathione peroxidase family.

717605:THECO RS01815
gene id: 717605:THECO_RS01815
uniprot id: L0EAC5
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS04210
gene id: 717605:THECO_RS04210
uniprot id: L0E9U1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

717605:THECO RS13225
gene id: 717605:THECO_RS13225
uniprot id: L0EG98
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

717605:THECO RS09505
gene id: 717605:THECO_RS09505
uniprot id: L0EEM4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

717605:THECO RS20310
gene id: 717605:THECO_RS20310
uniprot id: L0E9J7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS09975
gene id: 717605:THECO_RS09975
uniprot id: L0EEQ5
names: Similarity
messages: Belongs to the peptidase M16 family.

717605:THECO RS11975
gene id: 717605:THECO_RS11975
uniprot id: L0EG08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS00835
gene id: 717605:THECO_RS00835
uniprot id: L0E802
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

717605:THECO RS15570
gene id: 717605:THECO_RS15570
uniprot id: L0EHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

717605:THECO RS11110
gene id: 717605:THECO_RS11110
uniprot id: L0EF25
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS09395
gene id: 717605:THECO_RS09395
uniprot id: L0EBL8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

717605:THECO RS04470
gene id: 717605:THECO_RS04470
uniprot id: L0EBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18500
gene id: 717605:THECO_RS18500
uniprot id: L0EJ21
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

717605:THECO RS02960
gene id: 717605:THECO_RS02960
uniprot id: L0EAZ9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

717605:THECO RS01505
gene id: 717605:THECO_RS01505
uniprot id: L0EA79
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS18705
gene id: 717605:THECO_RS18705
uniprot id: L0EK25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

717605:THECO RS16955
gene id: 717605:THECO_RS16955
uniprot id: L0EGY3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

717605:THECO RS04955
gene id: 717605:THECO_RS04955
uniprot id: L0EDG3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS12060
gene id: 717605:THECO_RS12060
uniprot id: L0EG22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

717605:THECO RS06830
gene id: 717605:THECO_RS06830
uniprot id: L0EBB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS05980
gene id: 717605:THECO_RS05980
uniprot id: L0EAW6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS11190
gene id: 717605:THECO_RS11190
uniprot id: L0EFF0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

717605:THECO RS04010
gene id: 717605:THECO_RS04010
uniprot id: L0EBH0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717605:THECO RS17885
gene id: 717605:THECO_RS17885
uniprot id: L0EJ98
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

717605:THECO RS05870
gene id: 717605:THECO_RS05870
uniprot id: L0ECG8
names: Subcellular Location Annotation
messages: Cytoplasm

717605:THECO RS09685
gene id: 717605:THECO_RS09685
uniprot id: L0EEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

717605:THECO RS00645
gene id: 717605:THECO_RS00645
uniprot id: L0E9M4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS18480
gene id: 717605:THECO_RS18480
uniprot id: L0EHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

717605:THECO RS08590
gene id: 717605:THECO_RS08590
uniprot id: L0EFG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717605:THECO RS05150
gene id: 717605:THECO_RS05150
uniprot id: L0EC25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717605:THECO RS19200
gene id: 717605:THECO_RS19200
uniprot id: L0EJK4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

717605:THECO RS21055
gene id: 717605:THECO_RS21055
uniprot id: L0EEW4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS09445
gene id: 717605:THECO_RS09445
uniprot id: L0EFX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

717605:THECO RS11325
gene id: 717605:THECO_RS11325
uniprot id: L0EFN5
names: Similarity
messages: Belongs to the transpeptidase family.

717605:THECO RS17210
gene id: 717605:THECO_RS17210
uniprot id: L0EJY8
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

717605:THECO RS15125
gene id: 717605:THECO_RS15125
uniprot id: G4EC90
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS07320
gene id: 717605:THECO_RS07320
uniprot id: L0ECY1
names: Similarity
messages: Belongs to the HisA/HisF family.

717605:THECO RS17050
gene id: 717605:THECO_RS17050
uniprot id: L0EH05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

717605:THECO RS05465
gene id: 717605:THECO_RS05465
uniprot id: L0EAK9
names: Similarity
messages: Belongs to the peptidase M29 family.

717605:THECO RS08065
gene id: 717605:THECO_RS08065
uniprot id: L0EDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS17160
gene id: 717605:THECO_RS17160
uniprot id: L0EJY1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

717605:THECO RS18800
gene id: 717605:THECO_RS18800
uniprot id: L0EJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

717605:THECO RS15750
gene id: 717605:THECO_RS15750
uniprot id: L0EJC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

717605:THECO RS02640
gene id: 717605:THECO_RS02640
uniprot id: L0EAT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

717605:THECO RS06485
gene id: 717605:THECO_RS06485
uniprot id: L0ECS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

717605:THECO RS03285
gene id: 717605:THECO_RS03285
uniprot id: L0ECK6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS03905
gene id: 717605:THECO_RS03905
uniprot id: L0EBK9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

717605:THECO RS11935
gene id: 717605:THECO_RS11935
uniprot id: L0EFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS08485
gene id: 717605:THECO_RS08485
uniprot id: L0EE35
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

717605:THECO RS13905
gene id: 717605:THECO_RS13905
uniprot id: L0EIH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS08950
gene id: 717605:THECO_RS08950
uniprot id: L0EFN6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS00010
gene id: 717605:THECO_RS00010
uniprot id: L0E980
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

717605:THECO RS02815
gene id: 717605:THECO_RS02815
uniprot id: L0EAW8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

717605:THECO RS17300
gene id: 717605:THECO_RS17300
uniprot id: L0EH48
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

717605:THECO RS06135
gene id: 717605:THECO_RS06135
uniprot id: L0ECT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

717605:THECO RS02195
gene id: 717605:THECO_RS02195
uniprot id: L0EBX1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homodimer.
messages: Secreted

717605:THECO RS05095
gene id: 717605:THECO_RS05095
uniprot id: L0EC15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

717605:THECO RS13460
gene id: 717605:THECO_RS13460
uniprot id: L0EI80
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS17770
gene id: 717605:THECO_RS17770
uniprot id: L0EK83
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

717605:THECO RS01360
gene id: 717605:THECO_RS01360
uniprot id: L0EBI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

717605:THECO RS14825
gene id: 717605:THECO_RS14825
uniprot id: L0EFQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

717605:THECO RS01495
gene id: 717605:THECO_RS01495
uniprot id: L0E9T4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

717605:THECO RS15775
gene id: 717605:THECO_RS15775
uniprot id: L0EJC9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

717605:THECO RS10440
gene id: 717605:THECO_RS10440
uniprot id: L0EDB0
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

717605:THECO RS17820
gene id: 717605:THECO_RS17820
uniprot id: L0EK94
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

717605:THECO RS02655
gene id: 717605:THECO_RS02655
uniprot id: L0EAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

717605:THECO RS14710
gene id: 717605:THECO_RS14710
uniprot id: L0EHC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

717605:THECO RS07520
gene id: 717605:THECO_RS07520
uniprot id: L0EDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS05970
gene id: 717605:THECO_RS05970
uniprot id: L0ECI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS08560
gene id: 717605:THECO_RS08560
uniprot id: L0EE48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

717605:THECO RS14420
gene id: 717605:THECO_RS14420
uniprot id: L0EFH6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS10640
gene id: 717605:THECO_RS10640
uniprot id: L0EDF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

717605:THECO RS07245
gene id: 717605:THECO_RS07245
uniprot id: L0EDD4
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS12380
gene id: 717605:THECO_RS12380
uniprot id: L0EG84
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

717605:THECO RS09630
gene id: 717605:THECO_RS09630
uniprot id: L0EG20
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

717605:THECO RS01415
gene id: 717605:THECO_RS01415
uniprot id: L0EA17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

717605:THECO RS12955
gene id: 717605:THECO_RS12955
uniprot id: L0EGD3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

717605:THECO RS18630
gene id: 717605:THECO_RS18630
uniprot id: L0EK11
names: Similarity
messages: Belongs to the phosphohexose mutase family.

717605:THECO RS13850
gene id: 717605:THECO_RS13850
uniprot id: L0EH29
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS06905
gene id: 717605:THECO_RS06905
uniprot id: L0EBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

717605:THECO RS11170
gene id: 717605:THECO_RS11170
uniprot id: L0EF35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

717605:THECO RS14490
gene id: 717605:THECO_RS14490
uniprot id: L0EGX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

717605:THECO RS09005
gene id: 717605:THECO_RS09005
uniprot id: L0EDT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

717605:THECO RS12840
gene id: 717605:THECO_RS12840
uniprot id: L0EGG0
names: Similarity
messages: Belongs to the manganese catalase family.

717605:THECO RS17035
gene id: 717605:THECO_RS17035
uniprot id: L0EJX0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

717605:THECO RS01665
gene id: 717605:THECO_RS01665
uniprot id: L0EBM8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

717605:THECO RS07845
gene id: 717605:THECO_RS07845
uniprot id: L0EDH5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

717605:THECO RS18475
gene id: 717605:THECO_RS18475
uniprot id: L0EJ18
names: Similarity
messages: Belongs to the thioredoxin family.

717605:THECO RS11045
gene id: 717605:THECO_RS11045
uniprot id: L0EFI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

717605:THECO RS09820
gene id: 717605:THECO_RS09820
uniprot id: L0EET6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

717605:THECO RS09435
gene id: 717605:THECO_RS09435
uniprot id: L0EE13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

717605:THECO RS19115
gene id: 717605:THECO_RS19115
uniprot id: L0EKX6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

717605:THECO RS08880
gene id: 717605:THECO_RS08880
uniprot id: L0EDR7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

717605:THECO RS09995
gene id: 717605:THECO_RS09995
uniprot id: L0EG90
names: Similarity
messages: Belongs to the ribF family.

717605:THECO RS08585
gene id: 717605:THECO_RS08585
uniprot id: L0EE53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

717605:THECO RS12115
gene id: 717605:THECO_RS12115
uniprot id: L0EHF5
names: Similarity
messages: Belongs to the UPF0473 family.

717605:THECO RS04780
gene id: 717605:THECO_RS04780
uniprot id: L0EDD0
names: Similarity
messages: Belongs to the ribulokinase family.

717605:THECO RS14205
gene id: 717605:THECO_RS14205
uniprot id: L0EFD4
names: Similarity
messages: Belongs to the GSP E family.

717605:THECO RS02190
gene id: 717605:THECO_RS02190
uniprot id: L0EAJ6
names: Similarity
messages: Belongs to the fructosamine kinase family.

717605:THECO RS02975
gene id: 717605:THECO_RS02975
uniprot id: L0EAM9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

717605:THECO RS08770
gene id: 717605:THECO_RS08770
uniprot id: L0EFK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS10445
gene id: 717605:THECO_RS10445
uniprot id: L0EF55
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

717605:THECO RS01290
gene id: 717605:THECO_RS01290
uniprot id: L0E9P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

717605:THECO RS17700
gene id: 717605:THECO_RS17700
uniprot id: L0EHC8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS13415
gene id: 717605:THECO_RS13415
uniprot id: L0EGQ0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

717605:THECO RS18100
gene id: 717605:THECO_RS18100
uniprot id: L0EIV0
names: Similarity
messages: Belongs to the RutC family.

717605:THECO RS18700
gene id: 717605:THECO_RS18700
uniprot id: L0EJF3
names: Similarity
messages: Belongs to the peptidase S8 family.

717605:THECO RS17755
gene id: 717605:THECO_RS17755
uniprot id: L0EIM5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS09100
gene id: 717605:THECO_RS09100
uniprot id: L0EE81
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

717605:THECO RS07155
gene id: 717605:THECO_RS07155
uniprot id: L0ECU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS10270
gene id: 717605:THECO_RS10270
uniprot id: L0EF18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

717605:THECO RS10575
gene id: 717605:THECO_RS10575
uniprot id: L0EGK0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

717605:THECO RS07805
gene id: 717605:THECO_RS07805
uniprot id: L0EBU9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

717605:THECO RS10190
gene id: 717605:THECO_RS10190
uniprot id: L0EF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

717605:THECO RS09015
gene id: 717605:THECO_RS09015
uniprot id: L0EEC9
names: Similarity
messages: Belongs to the TrpC family.

717605:THECO RS11080
gene id: 717605:THECO_RS11080
uniprot id: L0EFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS14895
gene id: 717605:THECO_RS14895
uniprot id: L0EH55
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

717605:THECO RS13255
gene id: 717605:THECO_RS13255
uniprot id: L0EEW4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS04845
gene id: 717605:THECO_RS04845
uniprot id: L0EA74
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

717605:THECO RS03200
gene id: 717605:THECO_RS03200
uniprot id: L0E9B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS14000
gene id: 717605:THECO_RS14000
uniprot id: L0EH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

717605:THECO RS17280
gene id: 717605:THECO_RS17280
uniprot id: L0EIZ2
names: Subcellular Location Annotation
messages: Cell membrane

717605:THECO RS18755
gene id: 717605:THECO_RS18755
uniprot id: L0EK34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

717605:THECO RS11215
gene id: 717605:THECO_RS11215
uniprot id: L0EFF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

717605:THECO RS02830
gene id: 717605:THECO_RS02830
uniprot id: L0EJT4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS10045
gene id: 717605:THECO_RS10045
uniprot id: L0EGA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS00140
gene id: 717605:THECO_RS00140
uniprot id: L0E9A7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS01335
gene id: 717605:THECO_RS01335
uniprot id: L0EA02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

717605:THECO RS18735
gene id: 717605:THECO_RS18735
uniprot id: L0EI00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

717605:THECO RS18585
gene id: 717605:THECO_RS18585
uniprot id: L0EHX4
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

717605:THECO RS09350
gene id: 717605:THECO_RS09350
uniprot id: L0ECN8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

717605:THECO RS10375
gene id: 717605:THECO_RS10375
uniprot id: L0EGF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

717605:THECO RS15685
gene id: 717605:THECO_RS15685
uniprot id: L0EHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS05115
gene id: 717605:THECO_RS05115
uniprot id: L0EC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS07610
gene id: 717605:THECO_RS07610
uniprot id: L0EDI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS19110
gene id: 717605:THECO_RS19110
uniprot id: L0EJT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS15480
gene id: 717605:THECO_RS15480
uniprot id: L0EJ88
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01490
gene id: 717605:THECO_RS01490
uniprot id: L0EA32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

717605:THECO RS10160
gene id: 717605:THECO_RS10160
uniprot id: U3GKF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

717605:THECO RS05175
gene id: 717605:THECO_RS05175
uniprot id: L0EC29
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS12385
gene id: 717605:THECO_RS12385
uniprot id: L0EHK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

717605:THECO RS02705
gene id: 717605:THECO_RS02705
uniprot id: L0EAG2
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

717605:THECO RS17815
gene id: 717605:THECO_RS17815
uniprot id: L0EJ89
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

717605:THECO RS00085
gene id: 717605:THECO_RS00085
uniprot id: L0EAU1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

717605:THECO RS11955
gene id: 717605:THECO_RS11955
uniprot id: L0EHC5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS11820
gene id: 717605:THECO_RS11820
uniprot id: L0EHA2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

717605:THECO RS10210
gene id: 717605:THECO_RS10210
uniprot id: L0ED67
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

717605:THECO RS13385
gene id: 717605:THECO_RS13385
uniprot id: L0EI68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS00785
gene id: 717605:THECO_RS00785
uniprot id: U3GK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

717605:THECO RS02085
gene id: 717605:THECO_RS02085
uniprot id: L0EAH6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

717605:THECO RS09805
gene id: 717605:THECO_RS09805
uniprot id: L0EEM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

717605:THECO RS07345
gene id: 717605:THECO_RS07345
uniprot id: L0ECY7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

717605:THECO RS05145
gene id: 717605:THECO_RS05145
uniprot id: L0EDJ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS04860
gene id: 717605:THECO_RS04860
uniprot id: L0EBL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS11535
gene id: 717605:THECO_RS11535
uniprot id: L0EF96
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

717605:THECO RS11220
gene id: 717605:THECO_RS11220
uniprot id: L0EF44
names: Subcellular Location Annotation
messages: Cytoplasm

717605:THECO RS00055
gene id: 717605:THECO_RS00055
uniprot id: L0EAT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

717605:THECO RS17170
gene id: 717605:THECO_RS17170
uniprot id: L0EIB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

717605:THECO RS10040
gene id: 717605:THECO_RS10040
uniprot id: L0EEX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

717605:THECO RS09290
gene id: 717605:THECO_RS09290
uniprot id: L0EFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

717605:THECO RS06770
gene id: 717605:THECO_RS06770
uniprot id: L0ECX9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

717605:THECO RS19005
gene id: 717605:THECO_RS19005
uniprot id: L0EJI7
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

717605:THECO RS11655
gene id: 717605:THECO_RS11655
uniprot id: L0EFP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS00575
gene id: 717605:THECO_RS00575
uniprot id: L0E7W4
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS12280
gene id: 717605:THECO_RS12280
uniprot id: L0EG64
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

717605:THECO RS14945
gene id: 717605:THECO_RS14945
uniprot id: L0EH67
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01675
gene id: 717605:THECO_RS01675
uniprot id: L0E9V7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

717605:THECO RS13085
gene id: 717605:THECO_RS13085
uniprot id: L0EG65
names: Similarity
messages: Belongs to the glutamine synthetase family.

717605:THECO RS01420
gene id: 717605:THECO_RS01420
uniprot id: L0E9R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

717605:THECO RS14775
gene id: 717605:THECO_RS14775
uniprot id: L0EFP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09270
gene id: 717605:THECO_RS09270
uniprot id: L0EEB8
names: Similarity
messages: Belongs to the peptidase S11 family.

717605:THECO RS04590
gene id: 717605:THECO_RS04590
uniprot id: L0EBS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

717605:THECO RS07555
gene id: 717605:THECO_RS07555
uniprot id: L0ED18
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

717605:THECO RS08450
gene id: 717605:THECO_RS08450
uniprot id: L0EDJ7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS10220
gene id: 717605:THECO_RS10220
uniprot id: L0EGD0
names: Similarity
messages: Belongs to the FlgD family.

717605:THECO RS09360
gene id: 717605:THECO_RS09360
uniprot id: L0EFW8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

717605:THECO RS03250
gene id: 717605:THECO_RS03250
uniprot id: L0E9B9
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS09035
gene id: 717605:THECO_RS09035
uniprot id: L0ECH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS11770
gene id: 717605:THECO_RS11770
uniprot id: L0EH90
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.
messages: Membrane

717605:THECO RS17340
gene id: 717605:THECO_RS17340
uniprot id: L0EIS2
names: Similarity
messages: Belongs to the peptidase C40 family.

717605:THECO RS02255
gene id: 717605:THECO_RS02255
uniprot id: L0EAK7
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

717605:THECO RS13510
gene id: 717605:THECO_RS13510
uniprot id: L0EI92
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

717605:THECO RS02850
gene id: 717605:THECO_RS02850
uniprot id: L0EAR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

717605:THECO RS11520
gene id: 717605:THECO_RS11520
uniprot id: L0EDW4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

717605:THECO RS06985
gene id: 717605:THECO_RS06985
uniprot id: L0ED84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

717605:THECO RS06505
gene id: 717605:THECO_RS06505
uniprot id: L0EEC7
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

717605:THECO RS03005
gene id: 717605:THECO_RS03005
uniprot id: L0E984
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS03040
gene id: 717605:THECO_RS03040
uniprot id: L0ECF8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS03145
gene id: 717605:THECO_RS03145
uniprot id: L0EB01
names: Similarity
messages: Belongs to the PspA/IM30 family.

717605:THECO RS09940
gene id: 717605:THECO_RS09940
uniprot id: L0EEV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

717605:THECO RS14855
gene id: 717605:THECO_RS14855
uniprot id: L0EHK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

717605:THECO RS18085
gene id: 717605:THECO_RS18085
uniprot id: L0EJC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

717605:THECO RS04920
gene id: 717605:THECO_RS04920
uniprot id: L0EA93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS13240
gene id: 717605:THECO_RS13240
uniprot id: L0EI15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS10365
gene id: 717605:THECO_RS10365
uniprot id: L0ED94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

717605:THECO RS15310
gene id: 717605:THECO_RS15310
uniprot id: L0EG07
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

717605:THECO RS20275
gene id: 717605:THECO_RS20275
uniprot id: L0E9P6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

717605:THECO RS15200
gene id: 717605:THECO_RS15200
uniprot id: L0EHL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

717605:THECO RS08370
gene id: 717605:THECO_RS08370
uniprot id: L0EDV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS08855
gene id: 717605:THECO_RS08855
uniprot id: L0EDR4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS13920
gene id: 717605:THECO_RS13920
uniprot id: L0EF98
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

717605:THECO RS15015
gene id: 717605:THECO_RS15015
uniprot id: L0EHI0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

717605:THECO RS02990
gene id: 717605:THECO_RS02990
uniprot id: L0ECD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS17285
gene id: 717605:THECO_RS17285
uniprot id: L0EJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09255
gene id: 717605:THECO_RS09255
uniprot id: L0ECL6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

717605:THECO RS08765
gene id: 717605:THECO_RS08765
uniprot id: L0EE85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

717605:THECO RS06960
gene id: 717605:THECO_RS06960
uniprot id: L0ED80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

717605:THECO RS17775
gene id: 717605:THECO_RS17775
uniprot id: L0EJ00
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

717605:THECO RS00245
gene id: 717605:THECO_RS00245
uniprot id: L0E7P7
names: Similarity
messages: Belongs to the MQO family.

717605:THECO RS17910
gene id: 717605:THECO_RS17910
uniprot id: L0EJA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

717605:THECO RS18305
gene id: 717605:THECO_RS18305
uniprot id: L0EKI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS18385
gene id: 717605:THECO_RS18385
uniprot id: L0EKJ7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

717605:THECO RS05965
gene id: 717605:THECO_RS05965
uniprot id: L0EE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS13420
gene id: 717605:THECO_RS13420
uniprot id: L0EGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18580
gene id: 717605:THECO_RS18580
uniprot id: L0EK04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

717605:THECO RS09870
gene id: 717605:THECO_RS09870
uniprot id: L0EEU6
names: Similarity
messages: Belongs to the CinA family.

717605:THECO RS00840
gene id: 717605:THECO_RS00840
uniprot id: L0E9U9
names: Subcellular Location Annotation
messages: Cytoplasm

717605:THECO RS09950
gene id: 717605:THECO_RS09950
uniprot id: L0EEQ0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

717605:THECO RS06710
gene id: 717605:THECO_RS06710
uniprot id: L0EB88
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

717605:THECO RS19000
gene id: 717605:THECO_RS19000
uniprot id: L0EKW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

717605:THECO RS17710
gene id: 717605:THECO_RS17710
uniprot id: L0EK73
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS10635
gene id: 717605:THECO_RS10635
uniprot id: L0EET0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

717605:THECO RS04890
gene id: 717605:THECO_RS04890
uniprot id: L0EBL7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

717605:THECO RS01440
gene id: 717605:THECO_RS01440
uniprot id: L0EA22
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

717605:THECO RS09345
gene id: 717605:THECO_RS09345
uniprot id: L0EDZ7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS03945
gene id: 717605:THECO_RS03945
uniprot id: L0E9N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

717605:THECO RS06455
gene id: 717605:THECO_RS06455
uniprot id: L0ECS3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

717605:THECO RS18865
gene id: 717605:THECO_RS18865
uniprot id: L0EJQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12090
gene id: 717605:THECO_RS12090
uniprot id: L0EHE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

717605:THECO RS10370
gene id: 717605:THECO_RS10370
uniprot id: L0EF41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

717605:THECO RS13330
gene id: 717605:THECO_RS13330
uniprot id: L0EGS4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS01990
gene id: 717605:THECO_RS01990
uniprot id: L0EBT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

717605:THECO RS10240
gene id: 717605:THECO_RS10240
uniprot id: L0ED73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18240
gene id: 717605:THECO_RS18240
uniprot id: L0EIX5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

717605:THECO RS14625
gene id: 717605:THECO_RS14625
uniprot id: L0EIT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS01170
gene id: 717605:THECO_RS01170
uniprot id: L0E856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

717605:THECO RS18960
gene id: 717605:THECO_RS18960
uniprot id: L0EK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

717605:THECO RS13170
gene id: 717605:THECO_RS13170
uniprot id: L0EI02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

717605:THECO RS15060
gene id: 717605:THECO_RS15060
uniprot id: L0EJ27
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

717605:THECO RS11165
gene id: 717605:THECO_RS11165
uniprot id: L0EFE5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

717605:THECO RS15050
gene id: 717605:THECO_RS15050
uniprot id: L0EFV4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

717605:THECO RS17005
gene id: 717605:THECO_RS17005
uniprot id: L0EIT7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

717605:THECO RS10050
gene id: 717605:THECO_RS10050
uniprot id: L0EER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

717605:THECO RS03095
gene id: 717605:THECO_RS03095
uniprot id: L0EAZ3
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS11295
gene id: 717605:THECO_RS11295
uniprot id: L0EDT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS16620
gene id: 717605:THECO_RS16620
uniprot id: L0EJR2
names: Similarity
messages: Belongs to the GerABKA family.

717605:THECO RS06240
gene id: 717605:THECO_RS06240
uniprot id: L0EE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS16750
gene id: 717605:THECO_RS16750
uniprot id: L0EJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717605:THECO RS02695
gene id: 717605:THECO_RS02695
uniprot id: L0EC53
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

717605:THECO RS00215
gene id: 717605:THECO_RS00215
uniprot id: L0E960
names: Similarity
messages: Belongs to the ABC transporter superfamily.

717605:THECO RS14150
gene id: 717605:THECO_RS14150
uniprot id: L0EH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

717605:THECO RS15920
gene id: 717605:THECO_RS15920
uniprot id: L0EGE7
names: Subcellular Location Annotation
messages: Cell membrane

717605:THECO RS16735
gene id: 717605:THECO_RS16735
uniprot id: L0EIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12710
gene id: 717605:THECO_RS12710
uniprot id: L0EFY3
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

717605:THECO RS17220
gene id: 717605:THECO_RS17220
uniprot id: L0EIC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

717605:THECO RS13160
gene id: 717605:THECO_RS13160
uniprot id: L0EEU5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS12690
gene id: 717605:THECO_RS12690
uniprot id: L0EEJ3
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

717605:THECO RS02750
gene id: 717605:THECO_RS02750
uniprot id: L0EAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

717605:THECO RS15275
gene id: 717605:THECO_RS15275
uniprot id: L0EHN0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

717605:THECO RS18715
gene id: 717605:THECO_RS18715
uniprot id: L0EJN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

717605:THECO RS09530
gene id: 717605:THECO_RS09530
uniprot id: L0EG01
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

717605:THECO RS04355
gene id: 717605:THECO_RS04355
uniprot id: L0EBU0
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01160
gene id: 717605:THECO_RS01160
uniprot id: L0E9X1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

717605:THECO RS01980
gene id: 717605:THECO_RS01980
uniprot id: L0E8K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS17790
gene id: 717605:THECO_RS17790
uniprot id: L0EJ85
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

717605:THECO RS10875
gene id: 717605:THECO_RS10875
uniprot id: L0EEY3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

717605:THECO RS11285
gene id: 717605:THECO_RS11285
uniprot id: L0EFG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS15835
gene id: 717605:THECO_RS15835
uniprot id: L0EHP1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

717605:THECO RS19045
gene id: 717605:THECO_RS19045
uniprot id: L0EI43
names: Similarity
messages: Belongs to the ABC transporter superfamily.

717605:THECO RS14580
gene id: 717605:THECO_RS14580
uniprot id: L0EH94
names: Subcellular Location Annotation
messages: Cell membrane

717605:THECO RS13810
gene id: 717605:THECO_RS13810
uniprot id: L0EGW9
names: PTM
messages: Binds 1 heme c group covalently per subunit.

717605:THECO RS17225
gene id: 717605:THECO_RS17225
uniprot id: L0EH33
names: Similarity
messages: Belongs to the peptidase S8 family.

717605:THECO RS13525
gene id: 717605:THECO_RS13525
uniprot id: L0EGX1
names: Similarity
messages: Belongs to the GerABKA family.

717605:THECO RS08760
gene id: 717605:THECO_RS08760
uniprot id: L0ECD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

717605:THECO RS16410
gene id: 717605:THECO_RS16410
uniprot id: L0EJN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

717605:THECO RS15205
gene id: 717605:THECO_RS15205
uniprot id: L0EHB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

717605:THECO RS12735
gene id: 717605:THECO_RS12735
uniprot id: L0EFY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

717605:THECO RS08530
gene id: 717605:THECO_RS08530
uniprot id: L0ECA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

717605:THECO RS16545
gene id: 717605:THECO_RS16545
uniprot id: L0EJP9
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

717605:THECO RS10175
gene id: 717605:THECO_RS10175
uniprot id: U3GM50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

717605:THECO RS06090
gene id: 717605:THECO_RS06090
uniprot id: L0EE49
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS00655
gene id: 717605:THECO_RS00655
uniprot id: L0E7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

717605:THECO RS19170
gene id: 717605:THECO_RS19170
uniprot id: L0EJK3
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS12985
gene id: 717605:THECO_RS12985
uniprot id: L0EGD8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

717605:THECO RS10600
gene id: 717605:THECO_RS10600
uniprot id: L0EGK4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS10455
gene id: 717605:THECO_RS10455
uniprot id: L0EEZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS01475
gene id: 717605:THECO_RS01475
uniprot id: L0E8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

717605:THECO RS08830
gene id: 717605:THECO_RS08830
uniprot id: L0EDR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

717605:THECO RS00045
gene id: 717605:THECO_RS00045
uniprot id: L0E7K7
names: Similarity
messages: Belongs to the threonine synthase family.

717605:THECO RS04705
gene id: 717605:THECO_RS04705
uniprot id: L0EA46
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

717605:THECO RS09860
gene id: 717605:THECO_RS09860
uniprot id: L0EEB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

717605:THECO RS11500
gene id: 717605:THECO_RS11500
uniprot id: L0EFR9
names: Similarity
messages: Belongs to the UPF0178 family.

717605:THECO RS08780
gene id: 717605:THECO_RS08780
uniprot id: L0EDQ3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

717605:THECO RS14820
gene id: 717605:THECO_RS14820
uniprot id: L0EH40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

717605:THECO RS16660
gene id: 717605:THECO_RS16660
uniprot id: L0EGS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18010
gene id: 717605:THECO_RS18010
uniprot id: L0EHJ2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS03940
gene id: 717605:THECO_RS03940
uniprot id: L0EB29
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

717605:THECO RS01880
gene id: 717605:THECO_RS01880
uniprot id: L0EBR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

717605:THECO RS02530
gene id: 717605:THECO_RS02530
uniprot id: L0EAC8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS15765
gene id: 717605:THECO_RS15765
uniprot id: L0EGA2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

717605:THECO RS08800
gene id: 717605:THECO_RS08800
uniprot id: L0EE27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

717605:THECO RS18390
gene id: 717605:THECO_RS18390
uniprot id: L0EJ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

717605:THECO RS13120
gene id: 717605:THECO_RS13120
uniprot id: L0EHZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09865
gene id: 717605:THECO_RS09865
uniprot id: L0ECZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

717605:THECO RS12490
gene id: 717605:THECO_RS12490
uniprot id: L0EFT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

717605:THECO RS09990
gene id: 717605:THECO_RS09990
uniprot id: L0EEW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

717605:THECO RS08540
gene id: 717605:THECO_RS08540
uniprot id: L0EFG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

717605:THECO RS05790
gene id: 717605:THECO_RS05790
uniprot id: L0EC58
names: Similarity
messages: Belongs to the Nudix hydrolase family.

717605:THECO RS16015
gene id: 717605:THECO_RS16015
uniprot id: L0EHU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homodimer.
messages: Secreted

717605:THECO RS08680
gene id: 717605:THECO_RS08680
uniprot id: L0EDN5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

717605:THECO RS08375
gene id: 717605:THECO_RS08375
uniprot id: L0EDI8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

717605:THECO RS08725
gene id: 717605:THECO_RS08725
uniprot id: L0EE12
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS18380
gene id: 717605:THECO_RS18380
uniprot id: L0EJG0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

717605:THECO RS01180
gene id: 717605:THECO_RS01180
uniprot id: L0EBF1
names: Similarity
messages: Belongs to the ycf81 family.

717605:THECO RS06575
gene id: 717605:THECO_RS06575
uniprot id: L0ED10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717605:THECO RS13185
gene id: 717605:THECO_RS13185
uniprot id: L0EEU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

717605:THECO RS00845
gene id: 717605:THECO_RS00845
uniprot id: L0EB90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

717605:THECO RS07570
gene id: 717605:THECO_RS07570
uniprot id: L0EDC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

717605:THECO RS01985
gene id: 717605:THECO_RS01985
uniprot id: L0EAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS17640
gene id: 717605:THECO_RS17640
uniprot id: L0EIX6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717605:THECO RS12535
gene id: 717605:THECO_RS12535
uniprot id: L0EG62
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

717605:THECO RS11530
gene id: 717605:THECO_RS11530
uniprot id: L0EFM0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

717605:THECO RS08030
gene id: 717605:THECO_RS08030
uniprot id: L0EDR9
names: Similarity
messages: Belongs to the SleB family.

717605:THECO RS07045
gene id: 717605:THECO_RS07045
uniprot id: L0ECS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Monomer.

717605:THECO RS02570
gene id: 717605:THECO_RS02570
uniprot id: L0EAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18265
gene id: 717605:THECO_RS18265
uniprot id: L0EIX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

717605:THECO RS09140
gene id: 717605:THECO_RS09140
uniprot id: L0EEF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

717605:THECO RS17875
gene id: 717605:THECO_RS17875
uniprot id: L0EIQ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

717605:THECO RS00745
gene id: 717605:THECO_RS00745
uniprot id: L0E9P0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

717605:THECO RS01265
gene id: 717605:THECO_RS01265
uniprot id: L0E9N9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

717605:THECO RS03230
gene id: 717605:THECO_RS03230
uniprot id: L0EB81
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

717605:THECO RS02280
gene id: 717605:THECO_RS02280
uniprot id: L0E8Q8
names: Similarity
messages: Belongs to the SfsA family.

717605:THECO RS10835
gene id: 717605:THECO_RS10835
uniprot id: L0EFE2
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

717605:THECO RS09560
gene id: 717605:THECO_RS09560
uniprot id: L0EEH5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

717605:THECO RS02825
gene id: 717605:THECO_RS02825
uniprot id: L0EAR4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

717605:THECO RS02760
gene id: 717605:THECO_RS02760
uniprot id: L0E910
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

717605:THECO RS04915
gene id: 717605:THECO_RS04915
uniprot id: L0EBM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

717605:THECO RS12425
gene id: 717605:THECO_RS12425
uniprot id: L0EHL9
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS00910
gene id: 717605:THECO_RS00910
uniprot id: L0E812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

717605:THECO RS06745
gene id: 717605:THECO_RS06745
uniprot id: L0ECX4
names: Similarity
messages: Belongs to the HepT RNase toxin family.

717605:THECO RS03205
gene id: 717605:THECO_RS03205
uniprot id: L0EB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS07975
gene id: 717605:THECO_RS07975
uniprot id: L0EBX6
names: Similarity
messages: Belongs to the AAA ATPase family.

717605:THECO RS11260
gene id: 717605:THECO_RS11260
uniprot id: L0EFG3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

717605:THECO RS17395
gene id: 717605:THECO_RS17395
uniprot id: L0EH69
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

717605:THECO RS00885
gene id: 717605:THECO_RS00885
uniprot id: L0E808
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

717605:THECO RS05440
gene id: 717605:THECO_RS05440
uniprot id: L0EAK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

717605:THECO RS13275
gene id: 717605:THECO_RS13275
uniprot id: L0EEX8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

717605:THECO RS15085
gene id: 717605:THECO_RS15085
uniprot id: L0EHQ0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

717605:THECO RS08820
gene id: 717605:THECO_RS08820
uniprot id: L0EFL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

717605:THECO RS17680
gene id: 717605:THECO_RS17680
uniprot id: L0EJ70
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

717605:THECO RS10195
gene id: 717605:THECO_RS10195
uniprot id: L0EGC6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

717605:THECO RS08545
gene id: 717605:THECO_RS08545
uniprot id: L0EDX8
names: Similarity
messages: Belongs to the glutamine synthetase family.

717605:THECO RS05395
gene id: 717605:THECO_RS05395
uniprot id: L0ECC7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717605:THECO RS11830
gene id: 717605:THECO_RS11830
uniprot id: L0EFE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS05365
gene id: 717605:THECO_RS05365
uniprot id: L0EAJ0
names: Subcellular Location Annotation
messages: Cell membrane

717605:THECO RS02025
gene id: 717605:THECO_RS02025
uniprot id: L0EA28
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

717605:THECO RS09575
gene id: 717605:THECO_RS09575
uniprot id: L0EEN8
names: Similarity
messages: Belongs to the TlyA family.

717605:THECO RS01525
gene id: 717605:THECO_RS01525
uniprot id: L0E8C5
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

717605:THECO RS07505
gene id: 717605:THECO_RS07505
uniprot id: L0EBN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

717605:THECO RS04185
gene id: 717605:THECO_RS04185
uniprot id: L0E9T3
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS14680
gene id: 717605:THECO_RS14680
uniprot id: L0EIU8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

717605:THECO RS02140
gene id: 717605:THECO_RS02140
uniprot id: L0EAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS13285
gene id: 717605:THECO_RS13285
uniprot id: L0EI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

717605:THECO RS19095
gene id: 717605:THECO_RS19095
uniprot id: L0EJJ5
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS10150
gene id: 717605:THECO_RS10150
uniprot id: U3GKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

717605:THECO RS05070
gene id: 717605:THECO_RS05070
uniprot id: L0EC11
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS01375
gene id: 717605:THECO_RS01375
uniprot id: L0E892
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

717605:THECO RS05285
gene id: 717605:THECO_RS05285
uniprot id: L0EAH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

717605:THECO RS12340
gene id: 717605:THECO_RS12340
uniprot id: L0EG24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

717605:THECO RS16415
gene id: 717605:THECO_RS16415
uniprot id: L0EIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10035
gene id: 717605:THECO_RS10035
uniprot id: L0ED30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

717605:THECO RS02475
gene id: 717605:THECO_RS02475
uniprot id: L0EAB9
names: Similarity
messages: Belongs to the UPF0312 family.

717605:THECO RS11510
gene id: 717605:THECO_RS11510
uniprot id: L0EFL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

717605:THECO RS06445
gene id: 717605:THECO_RS06445
uniprot id: L0ECZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

717605:THECO RS11420
gene id: 717605:THECO_RS11420
uniprot id: L0EDV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

717605:THECO RS12555
gene id: 717605:THECO_RS12555
uniprot id: L0EHP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

717605:THECO RS13710
gene id: 717605:THECO_RS13710
uniprot id: L0EGK2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01295
gene id: 717605:THECO_RS01295
uniprot id: L0E877
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

717605:THECO RS02885
gene id: 717605:THECO_RS02885
uniprot id: L0E938
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

717605:THECO RS07700
gene id: 717605:THECO_RS07700
uniprot id: L0ED50
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

717605:THECO RS02925
gene id: 717605:THECO_RS02925
uniprot id: L0EAK8
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS08920
gene id: 717605:THECO_RS08920
uniprot id: L0EEB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

717605:THECO RS13020
gene id: 717605:THECO_RS13020
uniprot id: L0EER3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS06840
gene id: 717605:THECO_RS06840
uniprot id: L0EEI7
names: Similarity
messages: Belongs to the CapA family.

717605:THECO RS04095
gene id: 717605:THECO_RS04095
uniprot id: L0ED09
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS12960
gene id: 717605:THECO_RS12960
uniprot id: L0EG38
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

717605:THECO RS19090
gene id: 717605:THECO_RS19090
uniprot id: L0EKX1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

717605:THECO RS18820
gene id: 717605:THECO_RS18820
uniprot id: L0EKT7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

717605:THECO RS12670
gene id: 717605:THECO_RS12670
uniprot id: L0EGC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

717605:THECO RS00890
gene id: 717605:THECO_RS00890
uniprot id: L0E9V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

717605:THECO RS11695
gene id: 717605:THECO_RS11695
uniprot id: L0EH76
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

717605:THECO RS16755
gene id: 717605:THECO_RS16755
uniprot id: L0EIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717605:THECO RS14360
gene id: 717605:THECO_RS14360
uniprot id: L0EGU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

717605:THECO RS07200
gene id: 717605:THECO_RS07200
uniprot id: L0EEQ7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

717605:THECO RS01535
gene id: 717605:THECO_RS01535
uniprot id: L0EBM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

717605:THECO RS02070
gene id: 717605:THECO_RS02070
uniprot id: L0EAC4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

717605:THECO RS12135
gene id: 717605:THECO_RS12135
uniprot id: L0EG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

717605:THECO RS05180
gene id: 717605:THECO_RS05180
uniprot id: L0EBS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

717605:THECO RS01400
gene id: 717605:THECO_RS01400
uniprot id: L0E897
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

717605:THECO RS08865
gene id: 717605:THECO_RS08865
uniprot id: L0EEA1
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

717605:THECO RS17505
gene id: 717605:THECO_RS17505
uniprot id: L0EK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

717605:THECO RS17880
gene id: 717605:THECO_RS17880
uniprot id: L0EHG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS01115
gene id: 717605:THECO_RS01115
uniprot id: L0E9L6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS18640
gene id: 717605:THECO_RS18640
uniprot id: L0EJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

717605:THECO RS18750
gene id: 717605:THECO_RS18750
uniprot id: L0EJF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

717605:THECO RS02430
gene id: 717605:THECO_RS02430
uniprot id: L0E8U2
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

717605:THECO RS20760
gene id: 717605:THECO_RS20760
uniprot id: L0EI19
names: Function
messages: Required for transformation and DNA binding.

717605:THECO RS07025
gene id: 717605:THECO_RS07025
uniprot id: L0ECR9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

717605:THECO RS10390
gene id: 717605:THECO_RS10390
uniprot id: L0ED99
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

717605:THECO RS04120
gene id: 717605:THECO_RS04120
uniprot id: L0ED15
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS08795
gene id: 717605:THECO_RS08795
uniprot id: L0EFK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

717605:THECO RS16970
gene id: 717605:THECO_RS16970
uniprot id: L0EI90
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

717605:THECO RS01085
gene id: 717605:THECO_RS01085
uniprot id: L0E9L2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

717605:THECO RS06800
gene id: 717605:THECO_RS06800
uniprot id: L0ECM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

717605:THECO RS02480
gene id: 717605:THECO_RS02480
uniprot id: L0E8V2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

717605:THECO RS20690
gene id: 717605:THECO_RS20690
uniprot id: L0EI84
names: Similarity
messages: Belongs to the peptidase S16 family.

717605:THECO RS10015
gene id: 717605:THECO_RS10015
uniprot id: L0EEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

717605:THECO RS16615
gene id: 717605:THECO_RS16615
uniprot id: L0EIL8
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

717605:THECO RS17275
gene id: 717605:THECO_RS17275
uniprot id: L0EH43
names: Similarity
messages: Belongs to the PrpD family.

717605:THECO RS18435
gene id: 717605:THECO_RS18435
uniprot id: L0EKK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

717605:THECO RS02155
gene id: 717605:THECO_RS02155
uniprot id: L0EA54
names: Similarity
messages: Belongs to the ABC transporter superfamily.

717605:THECO RS06620
gene id: 717605:THECO_RS06620
uniprot id: L0ECI5
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS13945
gene id: 717605:THECO_RS13945
uniprot id: L0EFA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

717605:THECO RS03530
gene id: 717605:THECO_RS03530
uniprot id: L0EB62
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

717605:THECO RS07015
gene id: 717605:THECO_RS07015
uniprot id: L0EEM2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

717605:THECO RS01510
gene id: 717605:THECO_RS01510
uniprot id: L0EBL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

717605:THECO RS04630
gene id: 717605:THECO_RS04630
uniprot id: L0EA29
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

717605:THECO RS00610
gene id: 717605:THECO_RS00610
uniprot id: L0EEW4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS09705
gene id: 717605:THECO_RS09705
uniprot id: L0EG32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

717605:THECO RS02525
gene id: 717605:THECO_RS02525
uniprot id: L0EAL1
names: Similarity
messages: Belongs to the universal stress protein A family.

717605:THECO RS16065
gene id: 717605:THECO_RS16065
uniprot id: L0EHU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

717605:THECO RS11160
gene id: 717605:THECO_RS11160
uniprot id: L0EGW6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS02290
gene id: 717605:THECO_RS02290
uniprot id: L0EBY7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS12560
gene id: 717605:THECO_RS12560
uniprot id: L0EG66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

717605:THECO RS12465
gene id: 717605:THECO_RS12465
uniprot id: L0EEF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

717605:THECO RS19135
gene id: 717605:THECO_RS19135
uniprot id: L0EJT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

717605:THECO RS15595
gene id: 717605:THECO_RS15595
uniprot id: L0EHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09355
gene id: 717605:THECO_RS09355
uniprot id: L0EEJ5
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

717605:THECO RS15635
gene id: 717605:THECO_RS15635
uniprot id: L0EHJ9
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

717605:THECO RS18785
gene id: 717605:THECO_RS18785
uniprot id: L0EI07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

717605:THECO RS04950
gene id: 717605:THECO_RS04950
uniprot id: L0EC43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

717605:THECO RS07510
gene id: 717605:THECO_RS07510
uniprot id: L0EDH2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS11505
gene id: 717605:THECO_RS11505
uniprot id: L0EH37
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

717605:THECO RS06570
gene id: 717605:THECO_RS06570
uniprot id: L0EB61
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

717605:THECO RS05905
gene id: 717605:THECO_RS05905
uniprot id: L0EAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS01765
gene id: 717605:THECO_RS01765
uniprot id: L0EAB6
names: Similarity
messages: Belongs to the LOG family.

717605:THECO RS08775
gene id: 717605:THECO_RS08775
uniprot id: L0EE23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Membrane

717605:THECO RS10065
gene id: 717605:THECO_RS10065
uniprot id: L0EEX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

717605:THECO RS18805
gene id: 717605:THECO_RS18805
uniprot id: L0EK42
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS20065
gene id: 717605:THECO_RS20065
uniprot id: L0EK84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm

717605:THECO RS06795
gene id: 717605:THECO_RS06795
uniprot id: L0ECY4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS04610
gene id: 717605:THECO_RS04610
uniprot id: L0EBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

717605:THECO RS01650
gene id: 717605:THECO_RS01650
uniprot id: L0E9V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

717605:THECO RS16950
gene id: 717605:THECO_RS16950
uniprot id: L0EI86
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

717605:THECO RS12080
gene id: 717605:THECO_RS12080
uniprot id: L0EE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

717605:THECO RS13860
gene id: 717605:THECO_RS13860
uniprot id: L0EGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS00015
gene id: 717605:THECO_RS00015
uniprot id: L0E920
names: Similarity
messages: Belongs to the glutamate synthase family.

717605:THECO RS18285
gene id: 717605:THECO_RS18285
uniprot id: L0EJ77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

717605:THECO RS13200
gene id: 717605:THECO_RS13200
uniprot id: L0EG92
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS05680
gene id: 717605:THECO_RS05680
uniprot id: L0ECE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS02770
gene id: 717605:THECO_RS02770
uniprot id: L0EC69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

717605:THECO RS14165
gene id: 717605:THECO_RS14165
uniprot id: L0EH78
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

717605:THECO RS00620
gene id: 717605:THECO_RS00620
uniprot id: L0E9M1
names: Similarity
messages: Belongs to the PemK/MazF family.

717605:THECO RS19215
gene id: 717605:THECO_RS19215
uniprot id: L0EJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS17905
gene id: 717605:THECO_RS17905
uniprot id: L0EHH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

717605:THECO RS07740
gene id: 717605:THECO_RS07740
uniprot id: L0EEZ3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

717605:THECO RS14330
gene id: 717605:THECO_RS14330
uniprot id: L0EH49
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS02120
gene id: 717605:THECO_RS02120
uniprot id: L0EBV6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS06870
gene id: 717605:THECO_RS06870
uniprot id: L0ED01
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS16240
gene id: 717605:THECO_RS16240
uniprot id: L0EHX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS11290
gene id: 717605:THECO_RS11290
uniprot id: L0EF56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

717605:THECO RS01070
gene id: 717605:THECO_RS01070
uniprot id: L0E9Z6
names: Similarity
messages: Belongs to the CtsR family.

717605:THECO RS11805
gene id: 717605:THECO_RS11805
uniprot id: L0EFE3
names: Similarity
messages: Belongs to the CvfB family.

717605:THECO RS11970
gene id: 717605:THECO_RS11970
uniprot id: L0EE45
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

717605:THECO RS18925
gene id: 717605:THECO_RS18925
uniprot id: L0EJH8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

717605:THECO RS18665
gene id: 717605:THECO_RS18665
uniprot id: L0EJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

717605:THECO RS00170
gene id: 717605:THECO_RS00170
uniprot id: L0E7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

717605:THECO RS02865
gene id: 717605:THECO_RS02865
uniprot id: L0EAY0
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS01230
gene id: 717605:THECO_RS01230
uniprot id: L0EBG3
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS16940
gene id: 717605:THECO_RS16940
uniprot id: L0EJV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

717605:THECO RS12870
gene id: 717605:THECO_RS12870
uniprot id: L0EGG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

717605:THECO RS02985
gene id: 717605:THECO_RS02985
uniprot id: L0EB16
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

717605:THECO RS17520
gene id: 717605:THECO_RS17520
uniprot id: L0EH96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

717605:THECO RS05330
gene id: 717605:THECO_RS05330
uniprot id: L0EC56
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

717605:THECO RS14485
gene id: 717605:THECO_RS14485
uniprot id: L0EH77
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

717605:THECO RS13190
gene id: 717605:THECO_RS13190
uniprot id: L0EI06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

717605:THECO RS16895
gene id: 717605:THECO_RS16895
uniprot id: L0EIJ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

717605:THECO RS08505
gene id: 717605:THECO_RS08505
uniprot id: L0ECA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

717605:THECO RS08125
gene id: 717605:THECO_RS08125
uniprot id: L0EDT9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

717605:THECO RS09050
gene id: 717605:THECO_RS09050
uniprot id: L0EDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

717605:THECO RS18725
gene id: 717605:THECO_RS18725
uniprot id: L0EJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

717605:THECO RS07990
gene id: 717605:THECO_RS07990
uniprot id: L0EDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09790
gene id: 717605:THECO_RS09790
uniprot id: L0ECY2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS13940
gene id: 717605:THECO_RS13940
uniprot id: L0EGN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS11255
gene id: 717605:THECO_RS11255
uniprot id: L0EGY4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

717605:THECO RS04060
gene id: 717605:THECO_RS04060
uniprot id: L0EB55
names: Similarity
messages: Belongs to the SCO1/2 family.

717605:THECO RS15650
gene id: 717605:THECO_RS15650
uniprot id: L0EJB2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS11635
gene id: 717605:THECO_RS11635
uniprot id: L0EFB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

717605:THECO RS17810
gene id: 717605:THECO_RS17810
uniprot id: L0EHF0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

717605:THECO RS10155
gene id: 717605:THECO_RS10155
uniprot id: L0EEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

717605:THECO RS11615
gene id: 717605:THECO_RS11615
uniprot id: L0EDY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

717605:THECO RS05355
gene id: 717605:THECO_RS05355
uniprot id: L0EC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

717605:THECO RS15040
gene id: 717605:THECO_RS15040
uniprot id: L0EHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

717605:THECO RS04240
gene id: 717605:THECO_RS04240
uniprot id: L0EBS0
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS10315
gene id: 717605:THECO_RS10315
uniprot id: L0ED87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

717605:THECO RS06695
gene id: 717605:THECO_RS06695
uniprot id: L0EEF8
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS08205
gene id: 717605:THECO_RS08205
uniprot id: L0EDV4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

717605:THECO RS15195
gene id: 717605:THECO_RS15195
uniprot id: L0EJ48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

717605:THECO RS22540
gene id: 717605:THECO_RS22540
uniprot id: L0EET2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS05485
gene id: 717605:THECO_RS05485
uniprot id: L0EBZ3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

717605:THECO RS09920
gene id: 717605:THECO_RS09920
uniprot id: L0EG77
names: Similarity
messages: Belongs to the SleB family.

717605:THECO RS08195
gene id: 717605:THECO_RS08195
uniprot id: L0EDF2
names: Similarity
messages: Belongs to the manganese catalase family.

717605:THECO RS03855
gene id: 717605:THECO_RS03855
uniprot id: L0EB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS00630
gene id: 717605:THECO_RS00630
uniprot id: L0E7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

717605:THECO RS11030
gene id: 717605:THECO_RS11030
uniprot id: L0EFC2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS15660
gene id: 717605:THECO_RS15660
uniprot id: L0EHK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS05255
gene id: 717605:THECO_RS05255
uniprot id: L0EC41
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

717605:THECO RS15690
gene id: 717605:THECO_RS15690
uniprot id: L0EG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS07920
gene id: 717605:THECO_RS07920
uniprot id: L0EBW7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS02690
gene id: 717605:THECO_RS02690
uniprot id: L0EAU3
names: Similarity
messages: Belongs to the peptidase C40 family.

717605:THECO RS11570
gene id: 717605:THECO_RS11570
uniprot id: L0EFT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

717605:THECO RS15000
gene id: 717605:THECO_RS15000
uniprot id: L0EFU3
names: Similarity
messages: Belongs to the GARS family.

717605:THECO RS18980
gene id: 717605:THECO_RS18980
uniprot id: L0EJI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

717605:THECO RS19080
gene id: 717605:THECO_RS19080
uniprot id: L0EI47
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717605:THECO RS13855
gene id: 717605:THECO_RS13855
uniprot id: L0EIG7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

717605:THECO RS16480
gene id: 717605:THECO_RS16480
uniprot id: L0EIJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS02415
gene id: 717605:THECO_RS02415
uniprot id: L0EC09
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

717605:THECO RS02845
gene id: 717605:THECO_RS02845
uniprot id: L0EC84
names: Similarity
messages: Belongs to the FBPase class 2 family.

717605:THECO RS15730
gene id: 717605:THECO_RS15730
uniprot id: L0EHW8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

717605:THECO RS17020
gene id: 717605:THECO_RS17020
uniprot id: L0EIA1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

717605:THECO RS10760
gene id: 717605:THECO_RS10760
uniprot id: L0EEX0
names: Similarity
messages: Belongs to the asp23 family.

717605:THECO RS16160
gene id: 717605:THECO_RS16160
uniprot id: L0EI64
names: Similarity
messages: Belongs to the AlaDH/PNT family.

717605:THECO RS17025
gene id: 717605:THECO_RS17025
uniprot id: L0EH00
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

717605:THECO RS10880
gene id: 717605:THECO_RS10880
uniprot id: L0EDL6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

717605:THECO RS02100
gene id: 717605:THECO_RS02100
uniprot id: L0EA44
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS16315
gene id: 717605:THECO_RS16315
uniprot id: L0EJL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS04065
gene id: 717605:THECO_RS04065
uniprot id: L0E9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

717605:THECO RS02245
gene id: 717605:THECO_RS02245
uniprot id: L0EA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18965
gene id: 717605:THECO_RS18965
uniprot id: L0EI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10895
gene id: 717605:THECO_RS10895
uniprot id: L0EFA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

717605:THECO RS00680
gene id: 717605:THECO_RS00680
uniprot id: L0E7X9
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS06030
gene id: 717605:THECO_RS06030
uniprot id: L0EAX5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS19065
gene id: 717605:THECO_RS19065
uniprot id: L0EKW7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS05565
gene id: 717605:THECO_RS05565
uniprot id: L0ECB7
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

717605:THECO RS08935
gene id: 717605:THECO_RS08935
uniprot id: L0EDS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS09955
gene id: 717605:THECO_RS09955
uniprot id: L0EED5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS16250
gene id: 717605:THECO_RS16250
uniprot id: L0EIF0
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS13365
gene id: 717605:THECO_RS13365
uniprot id: L0EGP3
names: Subcellular Location Annotation
messages: Cell membrane

717605:THECO RS00980
gene id: 717605:THECO_RS00980
uniprot id: L0E9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

717605:THECO RS04055
gene id: 717605:THECO_RS04055
uniprot id: L0EBI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

717605:THECO RS08995
gene id: 717605:THECO_RS08995
uniprot id: L0EFP5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

717605:THECO RS10650
gene id: 717605:THECO_RS10650
uniprot id: L0EGL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

717605:THECO RS10290
gene id: 717605:THECO_RS10290
uniprot id: L0ED81
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

717605:THECO RS15370
gene id: 717605:THECO_RS15370
uniprot id: L0EJ73
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

717605:THECO RS17900
gene id: 717605:THECO_RS17900
uniprot id: L0EIQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

717605:THECO RS15210
gene id: 717605:THECO_RS15210
uniprot id: L0EFY7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

717605:THECO RS06390
gene id: 717605:THECO_RS06390
uniprot id: L0EB30
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

717605:THECO RS15100
gene id: 717605:THECO_RS15100
uniprot id: L0EH97
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS14700
gene id: 717605:THECO_RS14700
uniprot id: L0EHI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

717605:THECO RS19230
gene id: 717605:THECO_RS19230
uniprot id: L0EKB0
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS08900
gene id: 717605:THECO_RS08900
uniprot id: L0EFM6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

717605:THECO RS14225
gene id: 717605:THECO_RS14225
uniprot id: L0EGS2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

717605:THECO RS00390
gene id: 717605:THECO_RS00390
uniprot id: L0E9I6
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS11680
gene id: 717605:THECO_RS11680
uniprot id: L0EFQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

717605:THECO RS09525
gene id: 717605:THECO_RS09525
uniprot id: L0EEM9
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

717605:THECO RS03800
gene id: 717605:THECO_RS03800
uniprot id: L0EBC1
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01430
gene id: 717605:THECO_RS01430
uniprot id: L0EA66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

717605:THECO RS06225
gene id: 717605:THECO_RS06225
uniprot id: L0ECC5
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS01945
gene id: 717605:THECO_RS01945
uniprot id: L0EAA0
names: Similarity
messages: Belongs to the AHA1 family.

717605:THECO RS06785
gene id: 717605:THECO_RS06785
uniprot id: L0ED49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

717605:THECO RS05170
gene id: 717605:THECO_RS05170
uniprot id: L0EDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS08265
gene id: 717605:THECO_RS08265
uniprot id: L0EDT6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

717605:THECO RS08875
gene id: 717605:THECO_RS08875
uniprot id: L0EE42
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

717605:THECO RS11490
gene id: 717605:THECO_RS11490
uniprot id: L0EF88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

717605:THECO RS15830
gene id: 717605:THECO_RS15830
uniprot id: L0EHY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

717605:THECO RS17485
gene id: 717605:THECO_RS17485
uniprot id: L0EIV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS07075
gene id: 717605:THECO_RS07075
uniprot id: L0EBG4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

717605:THECO RS13885
gene id: 717605:THECO_RS13885
uniprot id: L0EGY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS04520
gene id: 717605:THECO_RS04520
uniprot id: L0EA06
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

717605:THECO RS15825
gene id: 717605:THECO_RS15825
uniprot id: L0EJD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS17405
gene id: 717605:THECO_RS17405
uniprot id: L0EK22
names: Subcellular Location Annotation
messages: Cell membrane

717605:THECO RS01480
gene id: 717605:THECO_RS01480
uniprot id: L0EA75
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

717605:THECO RS22455
gene id: 717605:THECO_RS22455
uniprot id: L0EAC0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

717605:THECO RS10200
gene id: 717605:THECO_RS10200
uniprot id: L0EEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

717605:THECO RS16420
gene id: 717605:THECO_RS16420
uniprot id: L0EI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS03740
gene id: 717605:THECO_RS03740
uniprot id: L0EBH6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

717605:THECO RS10345
gene id: 717605:THECO_RS10345
uniprot id: L0EF38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

717605:THECO RS05730
gene id: 717605:THECO_RS05730
uniprot id: L0ECE8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

717605:THECO RS10915
gene id: 717605:THECO_RS10915
uniprot id: L0EGS7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

717605:THECO RS16930
gene id: 717605:THECO_RS16930
uniprot id: L0EGX8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

717605:THECO RS09060
gene id: 717605:THECO_RS09060
uniprot id: L0EED9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

717605:THECO RS01515
gene id: 717605:THECO_RS01515
uniprot id: L0EA37
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

717605:THECO RS03510
gene id: 717605:THECO_RS03510
uniprot id: L0E9F8
names: Similarity
messages: Belongs to the DinB family.

717605:THECO RS00420
gene id: 717605:THECO_RS00420
uniprot id: L0E9B4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

717605:THECO RS06355
gene id: 717605:THECO_RS06355
uniprot id: L0ECE6
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS12720
gene id: 717605:THECO_RS12720
uniprot id: L0EGD6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

717605:THECO RS17165
gene id: 717605:THECO_RS17165
uniprot id: L0EIN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

717605:THECO RS22460
gene id: 717605:THECO_RS22460
uniprot id: L0EAA3
names: Similarity
messages: Belongs to the peptidase C40 family.

717605:THECO RS20715
gene id: 717605:THECO_RS20715
uniprot id: L0EJM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

717605:THECO RS19075
gene id: 717605:THECO_RS19075
uniprot id: L0EK85
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

717605:THECO RS00105
gene id: 717605:THECO_RS00105
uniprot id: L0E9D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS03935
gene id: 717605:THECO_RS03935
uniprot id: L0EBF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

717605:THECO RS06820
gene id: 717605:THECO_RS06820
uniprot id: L0ECZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

717605:THECO RS10080
gene id: 717605:THECO_RS10080
uniprot id: L0EEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

717605:THECO RS17990
gene id: 717605:THECO_RS17990
uniprot id: L0EJB0
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS02390
gene id: 717605:THECO_RS02390
uniprot id: L0EC05
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

717605:THECO RS09240
gene id: 717605:THECO_RS09240
uniprot id: L0EFU1
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS14155
gene id: 717605:THECO_RS14155
uniprot id: L0EGQ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

717605:THECO RS02015
gene id: 717605:THECO_RS02015
uniprot id: L0EBT6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

717605:THECO RS09300
gene id: 717605:THECO_RS09300
uniprot id: L0EDY9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

717605:THECO RS02550
gene id: 717605:THECO_RS02550
uniprot id: L0EAL5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

717605:THECO RS06220
gene id: 717605:THECO_RS06220
uniprot id: L0ECM8
names: Similarity
messages: Belongs to the FGGY kinase family.

717605:THECO RS08170
gene id: 717605:THECO_RS08170
uniprot id: L0EC18
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

717605:THECO RS06325
gene id: 717605:THECO_RS06325
uniprot id: L0ECP7
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

717605:THECO RS06495
gene id: 717605:THECO_RS06495
uniprot id: L0EB51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

717605:THECO RS16935
gene id: 717605:THECO_RS16935
uniprot id: L0EIS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

717605:THECO RS13220
gene id: 717605:THECO_RS13220
uniprot id: L0EGJ2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

717605:THECO RS08840
gene id: 717605:THECO_RS08840
uniprot id: L0EE98
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

717605:THECO RS09320
gene id: 717605:THECO_RS09320
uniprot id: L0EDZ3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

717605:THECO RS19290
gene id: 717605:THECO_RS19290
uniprot id: L0EI78
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

717605:THECO RS12825
gene id: 717605:THECO_RS12825
uniprot id: L0EHT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

717605:THECO RS05110
gene id: 717605:THECO_RS05110
uniprot id: L0EAD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS07995
gene id: 717605:THECO_RS07995
uniprot id: L0EBY0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

717605:THECO RS04570
gene id: 717605:THECO_RS04570
uniprot id: L0EBS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

717605:THECO RS03140
gene id: 717605:THECO_RS03140
uniprot id: L0ECH7
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS08100
gene id: 717605:THECO_RS08100
uniprot id: L0EC03
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

717605:THECO RS19860
gene id: 717605:THECO_RS19860
uniprot id: L0EII1
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

717605:THECO RS11540
gene id: 717605:THECO_RS11540
uniprot id: L0EDW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

717605:THECO RS10400
gene id: 717605:THECO_RS10400
uniprot id: L0EGG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

717605:THECO RS17330
gene id: 717605:THECO_RS17330
uniprot id: L0EJ02
names: Cofactor
messages: Binds 1 zinc ion per subunit.

717605:THECO RS11305
gene id: 717605:THECO_RS11305
uniprot id: L0EGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

717605:THECO RS14770
gene id: 717605:THECO_RS14770
uniprot id: L0EH30
names: Function
names: Subunit
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

717605:THECO RS10675
gene id: 717605:THECO_RS10675
uniprot id: L0EGL7
names: Similarity
messages: Belongs to the RemA family.

717605:THECO RS06050
gene id: 717605:THECO_RS06050
uniprot id: L0ECA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS02685
gene id: 717605:THECO_RS02685
uniprot id: L0E8Z6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS11340
gene id: 717605:THECO_RS11340
uniprot id: L0EF63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

717605:THECO RS12495
gene id: 717605:THECO_RS12495
uniprot id: L0EEF7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

717605:THECO RS08445
gene id: 717605:THECO_RS08445
uniprot id: L0EDW3
names: Similarity
messages: Belongs to the peptidase C40 family.

717605:THECO RS18765
gene id: 717605:THECO_RS18765
uniprot id: L0EJP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

717605:THECO RS07020
gene id: 717605:THECO_RS07020
uniprot id: L0ED32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

717605:THECO RS08380
gene id: 717605:THECO_RS08380
uniprot id: L0EC75
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

717605:THECO RS16990
gene id: 717605:THECO_RS16990
uniprot id: L0EIL6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

717605:THECO RS07220
gene id: 717605:THECO_RS07220
uniprot id: L0EDC9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

717605:THECO RS18565
gene id: 717605:THECO_RS18565
uniprot id: L0EJK6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

717605:THECO RS13260
gene id: 717605:THECO_RS13260
uniprot id: L0EGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

717605:THECO RS09680
gene id: 717605:THECO_RS09680
uniprot id: L0EG29
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

717605:THECO RS18505
gene id: 717605:THECO_RS18505
uniprot id: L0EHT7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

717605:THECO RS16645
gene id: 717605:THECO_RS16645
uniprot id: L0EJR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

717605:THECO RS17240
gene id: 717605:THECO_RS17240
uniprot id: L0EIQ0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

717605:THECO RS15340
gene id: 717605:THECO_RS15340
uniprot id: L0EHU4
names: Similarity
messages: Belongs to the glutamate synthase family.

717605:THECO RS11625
gene id: 717605:THECO_RS11625
uniprot id: L0EH62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

717605:THECO RS14345
gene id: 717605:THECO_RS14345
uniprot id: L0EHB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

717605:THECO RS12540
gene id: 717605:THECO_RS12540
uniprot id: L0EFV0
names: Similarity
messages: Belongs to the peptidase S16 family.

717605:THECO RS13530
gene id: 717605:THECO_RS13530
uniprot id: L0EI97
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

717605:THECO RS17045
gene id: 717605:THECO_RS17045
uniprot id: L0EIA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

717605:THECO RS11725
gene id: 717605:THECO_RS11725
uniprot id: L0EFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

717605:THECO RS12980
gene id: 717605:THECO_RS12980
uniprot id: L0EHW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

717605:THECO RS11965
gene id: 717605:THECO_RS11965
uniprot id: L0EFH1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

717605:THECO RS15915
gene id: 717605:THECO_RS15915
uniprot id: L0EHS2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS14780
gene id: 717605:THECO_RS14780
uniprot id: L0EHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS08365
gene id: 717605:THECO_RS08365
uniprot id: L0EFC8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

717605:THECO RS09550
gene id: 717605:THECO_RS09550
uniprot id: L0EEN3
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

717605:THECO RS12130
gene id: 717605:THECO_RS12130
uniprot id: L0EE78
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

717605:THECO RS16450
gene id: 717605:THECO_RS16450
uniprot id: L0EGP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

717605:THECO RS02650
gene id: 717605:THECO_RS02650
uniprot id: L0EAN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

717605:THECO RS02055
gene id: 717605:THECO_RS02055
uniprot id: L0E8L6
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

717605:THECO RS06005
gene id: 717605:THECO_RS06005
uniprot id: L0EAX0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

717605:THECO RS11300
gene id: 717605:THECO_RS11300
uniprot id: L0EFN0
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS12580
gene id: 717605:THECO_RS12580
uniprot id: L0EEH2
names: Similarity
messages: Belongs to the asparagine synthetase family.

717605:THECO RS15260
gene id: 717605:THECO_RS15260
uniprot id: L0EFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

717605:THECO RS05500
gene id: 717605:THECO_RS05500
uniprot id: L0EDS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

717605:THECO RS16890
gene id: 717605:THECO_RS16890
uniprot id: L0EJU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

717605:THECO RS16035
gene id: 717605:THECO_RS16035
uniprot id: L0EIA0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

717605:THECO RS11790
gene id: 717605:THECO_RS11790
uniprot id: L0EFX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS09620
gene id: 717605:THECO_RS09620
uniprot id: L0ECU6
names: Similarity
messages: Belongs to the asp23 family.

717605:THECO RS18355
gene id: 717605:THECO_RS18355
uniprot id: L0EKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

717605:THECO RS10530
gene id: 717605:THECO_RS10530
uniprot id: L0EF11
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

717605:THECO RS03755
gene id: 717605:THECO_RS03755
uniprot id: L0EAZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS07390
gene id: 717605:THECO_RS07390
uniprot id: L0EJT4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS02765
gene id: 717605:THECO_RS02765
uniprot id: L0EAV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

717605:THECO RS11270
gene id: 717605:THECO_RS11270
uniprot id: L0EDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

717605:THECO RS12765
gene id: 717605:THECO_RS12765
uniprot id: L0ED03
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS09945
gene id: 717605:THECO_RS09945
uniprot id: L0EG83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

717605:THECO RS11345
gene id: 717605:THECO_RS11345
uniprot id: L0EDT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

717605:THECO RS01955
gene id: 717605:THECO_RS01955
uniprot id: L0E8J5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

717605:THECO RS14325
gene id: 717605:THECO_RS14325
uniprot id: L0EIN1
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS13565
gene id: 717605:THECO_RS13565
uniprot id: L0EGH4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

717605:THECO RS00095
gene id: 717605:THECO_RS00095
uniprot id: L0E935
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

717605:THECO RS20680
gene id: 717605:THECO_RS20680
uniprot id: L0EHE8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

717605:THECO RS11710
gene id: 717605:THECO_RS11710
uniprot id: L0EDZ5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

717605:THECO RS15780
gene id: 717605:THECO_RS15780
uniprot id: L0EHX6
names: Similarity
messages: Belongs to the UPF0047 family.

717605:THECO RS10310
gene id: 717605:THECO_RS10310
uniprot id: L0EEL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

717605:THECO RS05415
gene id: 717605:THECO_RS05415
uniprot id: L0EAK0
names: Similarity
messages: Belongs to the ArsC family.

717605:THECO RS09970
gene id: 717605:THECO_RS09970
uniprot id: L0EG87
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

717605:THECO RS14930
gene id: 717605:THECO_RS14930
uniprot id: L0EHM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS15505
gene id: 717605:THECO_RS15505
uniprot id: L0EJ91
names: Similarity
messages: Belongs to the asparagine synthetase family.

717605:THECO RS00880
gene id: 717605:THECO_RS00880
uniprot id: L0E9I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

717605:THECO RS11515
gene id: 717605:THECO_RS11515
uniprot id: L0EF92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

717605:THECO RS04020
gene id: 717605:THECO_RS04020
uniprot id: L0E9P9
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

717605:THECO RS00395
gene id: 717605:THECO_RS00395
uniprot id: L0E9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

717605:THECO RS02505
gene id: 717605:THECO_RS02505
uniprot id: L0EAC3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

717605:THECO RS08710
gene id: 717605:THECO_RS08710
uniprot id: L0ECC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

717605:THECO RS07625
gene id: 717605:THECO_RS07625
uniprot id: L0ED36
names: Similarity
messages: Belongs to the UPF0145 family.

717605:THECO RS09000
gene id: 717605:THECO_RS09000
uniprot id: L0EE63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

717605:THECO RS08395
gene id: 717605:THECO_RS08395
uniprot id: L0EDV6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

717605:THECO RS01185
gene id: 717605:THECO_RS01185
uniprot id: L0E9X5
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS04375
gene id: 717605:THECO_RS04375
uniprot id: L0EBL8
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

717605:THECO RS18440
gene id: 717605:THECO_RS18440
uniprot id: L0EJA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

717605:THECO RS17890
gene id: 717605:THECO_RS17890
uniprot id: L0EKA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

717605:THECO RS10870
gene id: 717605:THECO_RS10870
uniprot id: L0EFA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

717605:THECO RS09755
gene id: 717605:THECO_RS09755
uniprot id: L0EG42
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

717605:THECO RS17080
gene id: 717605:THECO_RS17080
uniprot id: L0EIV3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

717605:THECO RS18830
gene id: 717605:THECO_RS18830
uniprot id: L0EK47
names: Function
messages: Required for transformation and DNA binding.

717605:THECO RS11745
gene id: 717605:THECO_RS11745
uniprot id: L0EH87
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

717605:THECO RS11945
gene id: 717605:THECO_RS11945
uniprot id: L0EE41
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

717605:THECO RS09695
gene id: 717605:THECO_RS09695
uniprot id: L0ECW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

717605:THECO RS11660
gene id: 717605:THECO_RS11660
uniprot id: L0EFB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

717605:THECO RS13480
gene id: 717605:THECO_RS13480
uniprot id: L0EGW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

717605:THECO RS10695
gene id: 717605:THECO_RS10695
uniprot id: L0EFA0
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

717605:THECO RS10380
gene id: 717605:THECO_RS10380
uniprot id: L0EEY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

717605:THECO RS10140
gene id: 717605:THECO_RS10140
uniprot id: L0EEZ8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

717605:THECO RS12715
gene id: 717605:THECO_RS12715
uniprot id: L0EEJ8
names: Similarity
messages: Belongs to the citrate synthase family.

717605:THECO RS16605
gene id: 717605:THECO_RS16605
uniprot id: L0EI33
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

717605:THECO RS17445
gene id: 717605:THECO_RS17445
uniprot id: L0EH79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12000
gene id: 717605:THECO_RS12000
uniprot id: L0EG13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

717605:THECO RS12705
gene id: 717605:THECO_RS12705
uniprot id: L0EG93
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

717605:THECO RS13025
gene id: 717605:THECO_RS13025
uniprot id: L0EGJ7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

717605:THECO RS02320
gene id: 717605:THECO_RS02320
uniprot id: L0EAG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

717605:THECO RS05165
gene id: 717605:THECO_RS05165
uniprot id: L0EC81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10145
gene id: 717605:THECO_RS10145
uniprot id: L0EGB8
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

717605:THECO RS01460
gene id: 717605:THECO_RS01460
uniprot id: L0EBK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

717605:THECO RS07695
gene id: 717605:THECO_RS07695
uniprot id: L0EDF0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

717605:THECO RS15470
gene id: 717605:THECO_RS15470
uniprot id: L0EG40
names: Similarity
messages: Belongs to the UDPGP type 2 family.

717605:THECO RS14145
gene id: 717605:THECO_RS14145
uniprot id: L0EIJ9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

717605:THECO RS18465
gene id: 717605:THECO_RS18465
uniprot id: L0EKL0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

717605:THECO RS10010
gene id: 717605:THECO_RS10010
uniprot id: L0ED25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

717605:THECO RS14400
gene id: 717605:THECO_RS14400
uniprot id: L0EHC0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS07595
gene id: 717605:THECO_RS07595
uniprot id: L0EDD1
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

717605:THECO RS06610
gene id: 717605:THECO_RS06610
uniprot id: L0EEE4
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

717605:THECO RS13655
gene id: 717605:THECO_RS13655
uniprot id: L0EGJ3
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS09185
gene id: 717605:THECO_RS09185
uniprot id: L0EEG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

717605:THECO RS09040
gene id: 717605:THECO_RS09040
uniprot id: L0EED4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

717605:THECO RS06480
gene id: 717605:THECO_RS06480
uniprot id: L0EEC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

717605:THECO RS10925
gene id: 717605:THECO_RS10925
uniprot id: L0EEZ4
names: Similarity
messages: Belongs to the UPF0473 family.

717605:THECO RS10505
gene id: 717605:THECO_RS10505
uniprot id: L0EF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10590
gene id: 717605:THECO_RS10590
uniprot id: L0EDE3
names: Similarity
messages: Belongs to the asp23 family.

717605:THECO RS10360
gene id: 717605:THECO_RS10360
uniprot id: L0EEM3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

717605:THECO RS04030
gene id: 717605:THECO_RS04030
uniprot id: L0ED02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

717605:THECO RS13360
gene id: 717605:THECO_RS13360
uniprot id: L0EI63
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS11765
gene id: 717605:THECO_RS11765
uniprot id: L0EFW9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

717605:THECO RS17665
gene id: 717605:THECO_RS17665
uniprot id: L0EIY1
names: Similarity
messages: Belongs to the DapA family.

717605:THECO RS06105
gene id: 717605:THECO_RS06105
uniprot id: L0EAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS00180
gene id: 717605:THECO_RS00180
uniprot id: L0EAW2
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS10070
gene id: 717605:THECO_RS10070
uniprot id: L0EGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

717605:THECO RS14395
gene id: 717605:THECO_RS14395
uniprot id: L0EFH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS10595
gene id: 717605:THECO_RS10595
uniprot id: L0EF82
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

717605:THECO RS09795
gene id: 717605:THECO_RS09795
uniprot id: L0EET1
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS16350
gene id: 717605:THECO_RS16350
uniprot id: L0EHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS04905
gene id: 717605:THECO_RS04905
uniprot id: L0EDF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

717605:THECO RS10305
gene id: 717605:THECO_RS10305
uniprot id: L0EEW3
names: Similarity
messages: Belongs to the DprA/Smf family.

717605:THECO RS10510
gene id: 717605:THECO_RS10510
uniprot id: L0EEQ4
names: Similarity
messages: Belongs to the UPF0045 family.

717605:THECO RS15940
gene id: 717605:THECO_RS15940
uniprot id: L0EI26
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS22525
gene id: 717605:THECO_RS22525
uniprot id: L0EFQ9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

717605:THECO RS13400
gene id: 717605:THECO_RS13400
uniprot id: L0EF06
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

717605:THECO RS00545
gene id: 717605:THECO_RS00545
uniprot id: L0E9L0
names: Similarity
messages: Belongs to the UPF0310 family.

717605:THECO RS03135
gene id: 717605:THECO_RS03135
uniprot id: L0EB64
names: Similarity
messages: Belongs to the PspA/IM30 family.

717605:THECO RS00770
gene id: 717605:THECO_RS00770
uniprot id: L0E9P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

717605:THECO RS04635
gene id: 717605:THECO_RS04635
uniprot id: L0EBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

717605:THECO RS04320
gene id: 717605:THECO_RS04320
uniprot id: L0EBM6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS06045
gene id: 717605:THECO_RS06045
uniprot id: L0ECJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS13425
gene id: 717605:THECO_RS13425
uniprot id: L0EF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10330
gene id: 717605:THECO_RS10330
uniprot id: L0EEW8
names: Similarity
messages: Belongs to the UPF0102 family.

717605:THECO RS06000
gene id: 717605:THECO_RS06000
uniprot id: L0EC91
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

717605:THECO RS08070
gene id: 717605:THECO_RS08070
uniprot id: L0EDC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS07350
gene id: 717605:THECO_RS07350
uniprot id: L0EBL3
names: Similarity
messages: Belongs to the UPF0236 family.

717605:THECO RS05625
gene id: 717605:THECO_RS05625
uniprot id: L0EAR2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

717605:THECO RS13410
gene id: 717605:THECO_RS13410
uniprot id: L0EI73
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS02035
gene id: 717605:THECO_RS02035
uniprot id: L0EAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS01885
gene id: 717605:THECO_RS01885
uniprot id: L0EA91
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

717605:THECO RS08740
gene id: 717605:THECO_RS08740
uniprot id: L0EE80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

717605:THECO RS15020
gene id: 717605:THECO_RS15020
uniprot id: L0EH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

717605:THECO RS19195
gene id: 717605:THECO_RS19195
uniprot id: L0EKY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPF0173 family.
messages: Counteracts the endogenous Pycsar antiviral defense system. Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
messages: Homodimer.

717605:THECO RS08815
gene id: 717605:THECO_RS08815
uniprot id: L0EE94
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. MtnX family.
messages: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

717605:THECO RS11470
gene id: 717605:THECO_RS11470
uniprot id: L0EDV8
names: Similarity
messages: Belongs to the peptidase S8 family.

717605:THECO RS11925
gene id: 717605:THECO_RS11925
uniprot id: L0EFZ8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

717605:THECO RS13875
gene id: 717605:THECO_RS13875
uniprot id: L0EH36
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS10275
gene id: 717605:THECO_RS10275
uniprot id: L0EGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

717605:THECO RS18205
gene id: 717605:THECO_RS18205
uniprot id: L0EHN2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

717605:THECO RS16765
gene id: 717605:THECO_RS16765
uniprot id: L0EGU8
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

717605:THECO RS11230
gene id: 717605:THECO_RS11230
uniprot id: L0EFL4
names: Similarity
messages: Belongs to the YggT family.

717605:THECO RS01755
gene id: 717605:THECO_RS01755
uniprot id: L0E9X3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

717605:THECO RS09825
gene id: 717605:THECO_RS09825
uniprot id: L0EG58
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

717605:THECO RS01370
gene id: 717605:THECO_RS01370
uniprot id: L0E9Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

717605:THECO RS18775
gene id: 717605:THECO_RS18775
uniprot id: L0EJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

717605:THECO RS13245
gene id: 717605:THECO_RS13245
uniprot id: L0EGJ6
names: Subcellular Location Annotation
messages: Membrane

717605:THECO RS16590
gene id: 717605:THECO_RS16590
uniprot id: L0EIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

717605:THECO RS01030
gene id: 717605:THECO_RS01030
uniprot id: L0E9Y6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

717605:THECO RS14470
gene id: 717605:THECO_RS14470
uniprot id: L0EFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

717605:THECO RS12240
gene id: 717605:THECO_RS12240
uniprot id: L0EG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

717605:THECO RS10075
gene id: 717605:THECO_RS10075
uniprot id: L0EES4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS18255
gene id: 717605:THECO_RS18255
uniprot id: L0EKH5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

717605:THECO RS01435
gene id: 717605:THECO_RS01435
uniprot id: L0EBK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

717605:THECO RS06680
gene id: 717605:THECO_RS06680
uniprot id: L0ECJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS07945
gene id: 717605:THECO_RS07945
uniprot id: L0EBX2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS14160
gene id: 717605:THECO_RS14160
uniprot id: L0EFC4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

717605:THECO RS18655
gene id: 717605:THECO_RS18655
uniprot id: L0EK16
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

717605:THECO RS08000
gene id: 717605:THECO_RS08000
uniprot id: L0EDR5
names: Similarity
messages: Belongs to the GbsR family.

717605:THECO RS11150
gene id: 717605:THECO_RS11150
uniprot id: L0EDR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

717605:THECO RS02740
gene id: 717605:THECO_RS02740
uniprot id: L0EAV3
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

717605:THECO RS02875
gene id: 717605:THECO_RS02875
uniprot id: L0EAS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

717605:THECO RS18740
gene id: 717605:THECO_RS18740
uniprot id: L0EJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

717605:THECO RS11330
gene id: 717605:THECO_RS11330
uniprot id: L0EH01
names: Similarity
messages: Belongs to the transpeptidase family.

717605:THECO RS08510
gene id: 717605:THECO_RS08510
uniprot id: L0EE38
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

717605:THECO RS10285
gene id: 717605:THECO_RS10285
uniprot id: L0EEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

717605:THECO RS01425
gene id: 717605:THECO_RS01425
uniprot id: L0E8A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

717605:THECO RS10165
gene id: 717605:THECO_RS10165
uniprot id: U3GK43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

717605:THECO RS07305
gene id: 717605:THECO_RS07305
uniprot id: L0EDE4
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

717605:THECO RS00040
gene id: 717605:THECO_RS00040
uniprot id: L0E925
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

717605:THECO RS03090
gene id: 717605:THECO_RS03090
uniprot id: L0ECG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane