709883:GA0070619 RS24505
gene id: 709883:GA0070619_RS24505
uniprot id: A0A1C5J1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

709883:GA0070619 RS24480
gene id: 709883:GA0070619_RS24480
uniprot id: A0A1C5J2H4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

709883:GA0070619 RS02715
gene id: 709883:GA0070619_RS02715
uniprot id: A0A1C5GVK5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

709883:GA0070619 RS26705
gene id: 709883:GA0070619_RS26705
uniprot id: A0A1C5J8F1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

709883:GA0070619 RS24620
gene id: 709883:GA0070619_RS24620
uniprot id: A0A1C5J228
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

709883:GA0070619 RS31560
gene id: 709883:GA0070619_RS31560
uniprot id: A0A1C5JMH3
names: Similarity
messages: Belongs to the thioredoxin family.

709883:GA0070619 RS24605
gene id: 709883:GA0070619_RS24605
uniprot id: A0A1C5J1X9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

709883:GA0070619 RS24630
gene id: 709883:GA0070619_RS24630
uniprot id: A0A1C5J2H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

709883:GA0070619 RS24575
gene id: 709883:GA0070619_RS24575
uniprot id: A0A1C5J1V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

709883:GA0070619 RS24535
gene id: 709883:GA0070619_RS24535
uniprot id: A0A1C5J1Q3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

709883:GA0070619 RS24615
gene id: 709883:GA0070619_RS24615
uniprot id: A0A1C5J377
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

709883:GA0070619 RS12140
gene id: 709883:GA0070619_RS12140
uniprot id: A0A1C5HXF8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

709883:GA0070619 RS27905
gene id: 709883:GA0070619_RS27905
uniprot id: A0A1C5JBV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

709883:GA0070619 RS18765
gene id: 709883:GA0070619_RS18765
uniprot id: A0A1C5IK77
names: Subcellular Location Annotation
messages: Cytoplasm

709883:GA0070619 RS32005
gene id: 709883:GA0070619_RS32005
uniprot id: A0A1C5JNW3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

709883:GA0070619 RS24485
gene id: 709883:GA0070619_RS24485
uniprot id: A0A1C5J1I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

709883:GA0070619 RS21515
gene id: 709883:GA0070619_RS21515
uniprot id: A0A1C5ISZ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

709883:GA0070619 RS24490
gene id: 709883:GA0070619_RS24490
uniprot id: A0A1C5J1N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

709883:GA0070619 RS00895
gene id: 709883:GA0070619_RS00895
uniprot id: A0A1C5GNN3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

709883:GA0070619 RS27915
gene id: 709883:GA0070619_RS27915
uniprot id: A0A1C5JBT0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

709883:GA0070619 RS03685
gene id: 709883:GA0070619_RS03685
uniprot id: A0A1C5H0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

709883:GA0070619 RS28080
gene id: 709883:GA0070619_RS28080
uniprot id: A0A1C5JCC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

709883:GA0070619 RS26960
gene id: 709883:GA0070619_RS26960
uniprot id: A0A1C5J8Z4
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

709883:GA0070619 RS24645
gene id: 709883:GA0070619_RS24645
uniprot id: A0A1C5J329
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

709883:GA0070619 RS24650
gene id: 709883:GA0070619_RS24650
uniprot id: A0A1C5J2C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

709883:GA0070619 RS23520
gene id: 709883:GA0070619_RS23520
uniprot id: A0A1C5IYX4
names: Subcellular Location Annotation
messages: Cytoplasm

709883:GA0070619 RS00435
gene id: 709883:GA0070619_RS00435
uniprot id: A0A1C5GLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

709883:GA0070619 RS25655
gene id: 709883:GA0070619_RS25655
uniprot id: A0A1C5J6M4
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

709883:GA0070619 RS04990
gene id: 709883:GA0070619_RS04990
uniprot id: A0A1C5H430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

709883:GA0070619 RS02770
gene id: 709883:GA0070619_RS02770
uniprot id: A0A1C5GVY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

709883:GA0070619 RS31830
gene id: 709883:GA0070619_RS31830
uniprot id: A0A1C5JN96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

709883:GA0070619 RS12690
gene id: 709883:GA0070619_RS12690
uniprot id: A0A1C5HZF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

709883:GA0070619 RS24600
gene id: 709883:GA0070619_RS24600
uniprot id: A0A1C5J200
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

709883:GA0070619 RS03440
gene id: 709883:GA0070619_RS03440
uniprot id: A0A1C5GY67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

709883:GA0070619 RS24680
gene id: 709883:GA0070619_RS24680
uniprot id: A0A1C5J2F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

709883:GA0070619 RS18700
gene id: 709883:GA0070619_RS18700
uniprot id: A0A1C5IJ79
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

709883:GA0070619 RS24730
gene id: 709883:GA0070619_RS24730
uniprot id: A0A1C5J415
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

709883:GA0070619 RS08960
gene id: 709883:GA0070619_RS08960
uniprot id: A0A1C5HK47
names: Subcellular Location Annotation
messages: Cytoplasm

709883:GA0070619 RS07845
gene id: 709883:GA0070619_RS07845
uniprot id: A0A1C5HFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

709883:GA0070619 RS20525
gene id: 709883:GA0070619_RS20525
uniprot id: A0A1C5IQ06
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

709883:GA0070619 RS26865
gene id: 709883:GA0070619_RS26865
uniprot id: A0A1C5JAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

709883:GA0070619 RS28935
gene id: 709883:GA0070619_RS28935
uniprot id: A0A1C5JFY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

709883:GA0070619 RS08040
gene id: 709883:GA0070619_RS08040
uniprot id: A0A1C5HGL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

709883:GA0070619 RS24590
gene id: 709883:GA0070619_RS24590
uniprot id: A0A1C5J246
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

709883:GA0070619 RS01030
gene id: 709883:GA0070619_RS01030
uniprot id: A0A1C5GNZ8
names: Similarity
messages: Belongs to the UPF0434 family.

709883:GA0070619 RS01155
gene id: 709883:GA0070619_RS01155
uniprot id: A0A1C5GPS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

709883:GA0070619 RS30010
gene id: 709883:GA0070619_RS30010
uniprot id: A0A1C5JI19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

709883:GA0070619 RS24585
gene id: 709883:GA0070619_RS24585
uniprot id: A0A1C5J1Z2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

709883:GA0070619 RS24300
gene id: 709883:GA0070619_RS24300
uniprot id: A0A1C5J1G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

709883:GA0070619 RS24560
gene id: 709883:GA0070619_RS24560
uniprot id: A0A1C5J1U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

709883:GA0070619 RS07910
gene id: 709883:GA0070619_RS07910
uniprot id: A0A1C5HFN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

709883:GA0070619 RS21520
gene id: 709883:GA0070619_RS21520
uniprot id: A0A1C5ISZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

709883:GA0070619 RS30680
gene id: 709883:GA0070619_RS30680
uniprot id: A0A1C5JK26
names: Similarity
messages: Belongs to the citrate synthase family.

709883:GA0070619 RS24580
gene id: 709883:GA0070619_RS24580
uniprot id: A0A1C5J3J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

709883:GA0070619 RS07225
gene id: 709883:GA0070619_RS07225
uniprot id: A0A1C5HD28
names: Subcellular Location Annotation
messages: Cytoplasm

709883:GA0070619 RS18680
gene id: 709883:GA0070619_RS18680
uniprot id: A0A1C5IJA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane