706587:DESTI RS05840
gene id: 706587:DESTI_RS05840
uniprot id: I4C2U2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

706587:DESTI RS12615
gene id: 706587:DESTI_RS12615
uniprot id: I4C6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

706587:DESTI RS17910
gene id: 706587:DESTI_RS17910
uniprot id: I4C9K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

706587:DESTI RS26570
gene id: 706587:DESTI_RS26570
uniprot id: I4CEF7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS15935
gene id: 706587:DESTI_RS15935
uniprot id: I4C8G7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18065
gene id: 706587:DESTI_RS18065
uniprot id: I4C9N6
names: Similarity
messages: Belongs to the UPF0045 family.

706587:DESTI RS10375
gene id: 706587:DESTI_RS10375
uniprot id: I4C5D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS25105
gene id: 706587:DESTI_RS25105
uniprot id: I4CDN1
names: Similarity
messages: Belongs to the PstS family.

706587:DESTI RS01950
gene id: 706587:DESTI_RS01950
uniprot id: I4C0N6
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

706587:DESTI RS21040
gene id: 706587:DESTI_RS21040
uniprot id: I4CBD7
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

706587:DESTI RS04130
gene id: 706587:DESTI_RS04130
uniprot id: I4C1W3
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

706587:DESTI RS09645
gene id: 706587:DESTI_RS09645
uniprot id: I4C4Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS14150
gene id: 706587:DESTI_RS14150
uniprot id: I4C7H5
names: Similarity
messages: Belongs to the UPF0434 family.

706587:DESTI RS19445
gene id: 706587:DESTI_RS19445
uniprot id: I4CAG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS26090
gene id: 706587:DESTI_RS26090
uniprot id: I4CE58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

706587:DESTI RS12875
gene id: 706587:DESTI_RS12875
uniprot id: I4C6S3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

706587:DESTI RS00285
gene id: 706587:DESTI_RS00285
uniprot id: I4BZR5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

706587:DESTI RS06810
gene id: 706587:DESTI_RS06810
uniprot id: I4C3D5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS09065
gene id: 706587:DESTI_RS09065
uniprot id: I4C4M8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS22465
gene id: 706587:DESTI_RS22465
uniprot id: I4CC69
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

706587:DESTI RS20820
gene id: 706587:DESTI_RS20820
uniprot id: I4CB93
names: Similarity
messages: Belongs to the glutamate synthase family.

706587:DESTI RS17645
gene id: 706587:DESTI_RS17645
uniprot id: I4C9F7
names: Similarity
messages: Belongs to the PstS family.

706587:DESTI RS12245
gene id: 706587:DESTI_RS12245
uniprot id: I4C6E5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS19360
gene id: 706587:DESTI_RS19360
uniprot id: I4CAE7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

706587:DESTI RS23565
gene id: 706587:DESTI_RS23565
uniprot id: I4CCT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS27760
gene id: 706587:DESTI_RS27760
uniprot id: I4CF29
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

706587:DESTI RS20800
gene id: 706587:DESTI_RS20800
uniprot id: I4CB89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

706587:DESTI RS14480
gene id: 706587:DESTI_RS14480
uniprot id: I4C7N7
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.

706587:DESTI RS19255
gene id: 706587:DESTI_RS19255
uniprot id: I4CAC5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS05735
gene id: 706587:DESTI_RS05735
uniprot id: I4C2S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

706587:DESTI RS26960
gene id: 706587:DESTI_RS26960
uniprot id: I4CEN5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

706587:DESTI RS03975
gene id: 706587:DESTI_RS03975
uniprot id: I4C1T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

706587:DESTI RS20545
gene id: 706587:DESTI_RS20545
uniprot id: I4CB38
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

706587:DESTI RS21580
gene id: 706587:DESTI_RS21580
uniprot id: I4CBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS12180
gene id: 706587:DESTI_RS12180
uniprot id: I4C6D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS09730
gene id: 706587:DESTI_RS09730
uniprot id: I4C510
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

706587:DESTI RS09805
gene id: 706587:DESTI_RS09805
uniprot id: I4C524
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS27650
gene id: 706587:DESTI_RS27650
uniprot id: I4CF08
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

706587:DESTI RS01020
gene id: 706587:DESTI_RS01020
uniprot id: I4C060
names: Similarity
messages: Belongs to the AdoMet synthase family.

706587:DESTI RS28190
gene id: 706587:DESTI_RS28190
uniprot id: I4BZU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS15510
gene id: 706587:DESTI_RS15510
uniprot id: I4C886
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

706587:DESTI RS06275
gene id: 706587:DESTI_RS06275
uniprot id: I4C327
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

706587:DESTI RS21325
gene id: 706587:DESTI_RS21325
uniprot id: I4CBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS08775
gene id: 706587:DESTI_RS08775
uniprot id: I4C4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

706587:DESTI RS00370
gene id: 706587:DESTI_RS00370
uniprot id: I4BZT1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS26180
gene id: 706587:DESTI_RS26180
uniprot id: I4CE76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

706587:DESTI RS15710
gene id: 706587:DESTI_RS15710
uniprot id: I4C8C5
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

706587:DESTI RS18745
gene id: 706587:DESTI_RS18745
uniprot id: I4CA24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

706587:DESTI RS20375
gene id: 706587:DESTI_RS20375
uniprot id: I4CB04
names: Similarity
messages: Belongs to the HypD family.

706587:DESTI RS07495
gene id: 706587:DESTI_RS07495
uniprot id: I4C3S0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

706587:DESTI RS01695
gene id: 706587:DESTI_RS01695
uniprot id: I4C0I5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06300
gene id: 706587:DESTI_RS06300
uniprot id: I4C332
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS06115
gene id: 706587:DESTI_RS06115
uniprot id: I4C2Z4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

706587:DESTI RS23770
gene id: 706587:DESTI_RS23770
uniprot id: I4CCX3
names: Similarity
messages: Belongs to the PrpD family.

706587:DESTI RS12635
gene id: 706587:DESTI_RS12635
uniprot id: I4C6M1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

706587:DESTI RS19755
gene id: 706587:DESTI_RS19755
uniprot id: I4CAN0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS10725
gene id: 706587:DESTI_RS10725
uniprot id: I4C5J5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS00350
gene id: 706587:DESTI_RS00350
uniprot id: I4BZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

706587:DESTI RS05320
gene id: 706587:DESTI_RS05320
uniprot id: I4C2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

706587:DESTI RS06630
gene id: 706587:DESTI_RS06630
uniprot id: I4C398
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS23245
gene id: 706587:DESTI_RS23245
uniprot id: I4CCM2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

706587:DESTI RS04840
gene id: 706587:DESTI_RS04840
uniprot id: I4C294
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS03955
gene id: 706587:DESTI_RS03955
uniprot id: I4C1S8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

706587:DESTI RS13700
gene id: 706587:DESTI_RS13700
uniprot id: I4C790
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

706587:DESTI RS00705
gene id: 706587:DESTI_RS00705
uniprot id: I4BZZ5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

706587:DESTI RS00870
gene id: 706587:DESTI_RS00870
uniprot id: I4C028
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

706587:DESTI RS14665
gene id: 706587:DESTI_RS14665
uniprot id: I4C7S6
names: Similarity
messages: Belongs to the glutamate synthase family.

706587:DESTI RS02015
gene id: 706587:DESTI_RS02015
uniprot id: I4C0P7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

706587:DESTI RS02500
gene id: 706587:DESTI_RS02500
uniprot id: I4C0Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS19365
gene id: 706587:DESTI_RS19365
uniprot id: I4CAE8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06100
gene id: 706587:DESTI_RS06100
uniprot id: I4C2Z1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

706587:DESTI RS09975
gene id: 706587:DESTI_RS09975
uniprot id: I4C556
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS04920
gene id: 706587:DESTI_RS04920
uniprot id: I4C2B1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18930
gene id: 706587:DESTI_RS18930
uniprot id: I4CA58
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

706587:DESTI RS22875
gene id: 706587:DESTI_RS22875
uniprot id: I4CCF3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

706587:DESTI RS26095
gene id: 706587:DESTI_RS26095
uniprot id: I4CE45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

706587:DESTI RS21650
gene id: 706587:DESTI_RS21650
uniprot id: I4CBQ6
names: Similarity
messages: Belongs to the UPF0111 family.

706587:DESTI RS22770
gene id: 706587:DESTI_RS22770
uniprot id: I4CCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS05245
gene id: 706587:DESTI_RS05245
uniprot id: I4C2I0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS10800
gene id: 706587:DESTI_RS10800
uniprot id: I4C5L1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS13750
gene id: 706587:DESTI_RS13750
uniprot id: I4C7A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS13740
gene id: 706587:DESTI_RS13740
uniprot id: I4C798
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

706587:DESTI RS06640
gene id: 706587:DESTI_RS06640
uniprot id: I4C3A0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

706587:DESTI RS22110
gene id: 706587:DESTI_RS22110
uniprot id: I4CC00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

706587:DESTI RS04530
gene id: 706587:DESTI_RS04530
uniprot id: I4C232
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS16630
gene id: 706587:DESTI_RS16630
uniprot id: I4C8V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

706587:DESTI RS25140
gene id: 706587:DESTI_RS25140
uniprot id: I4CDN8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS17795
gene id: 706587:DESTI_RS17795
uniprot id: I4C9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

706587:DESTI RS02200
gene id: 706587:DESTI_RS02200
uniprot id: I4C0T4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

706587:DESTI RS00440
gene id: 706587:DESTI_RS00440
uniprot id: I4BZU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

706587:DESTI RS15545
gene id: 706587:DESTI_RS15545
uniprot id: I4C893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS23330
gene id: 706587:DESTI_RS23330
uniprot id: I4CCN7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS15945
gene id: 706587:DESTI_RS15945
uniprot id: I4C8G9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS05060
gene id: 706587:DESTI_RS05060
uniprot id: I4C2E0
names: Similarity
messages: Belongs to the AdoMet synthase family.

706587:DESTI RS12160
gene id: 706587:DESTI_RS12160
uniprot id: I4C6C7
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

706587:DESTI RS17335
gene id: 706587:DESTI_RS17335
uniprot id: I4C997
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS07910
gene id: 706587:DESTI_RS07910
uniprot id: I4C401
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS31360
gene id: 706587:DESTI_RS31360
uniprot id: I4C1N8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

706587:DESTI RS15285
gene id: 706587:DESTI_RS15285
uniprot id: I4C842
names: Similarity
messages: Belongs to the transglycosylase Slt family.

706587:DESTI RS27205
gene id: 706587:DESTI_RS27205
uniprot id: I4CES5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

706587:DESTI RS25985
gene id: 706587:DESTI_RS25985
uniprot id: I4CE41
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

706587:DESTI RS01620
gene id: 706587:DESTI_RS01620
uniprot id: I4C0G9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS03410
gene id: 706587:DESTI_RS03410
uniprot id: I4C1H3
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

706587:DESTI RS07400
gene id: 706587:DESTI_RS07400
uniprot id: I4C3Q1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS10840
gene id: 706587:DESTI_RS10840
uniprot id: I4C5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

706587:DESTI RS09565
gene id: 706587:DESTI_RS09565
uniprot id: I4C4X9
names: Similarity
messages: Belongs to the AOR/FOR family.

706587:DESTI RS09295
gene id: 706587:DESTI_RS09295
uniprot id: I4C4S4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

706587:DESTI RS19770
gene id: 706587:DESTI_RS19770
uniprot id: I4CAN3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

706587:DESTI RS27780
gene id: 706587:DESTI_RS27780
uniprot id: I4CF33
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

706587:DESTI RS13290
gene id: 706587:DESTI_RS13290
uniprot id: I4C711
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS08995
gene id: 706587:DESTI_RS08995
uniprot id: I4C4L6
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

706587:DESTI RS03475
gene id: 706587:DESTI_RS03475
uniprot id: I4C1I5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS27385
gene id: 706587:DESTI_RS27385
uniprot id: I4CEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS08865
gene id: 706587:DESTI_RS08865
uniprot id: I4C4J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

706587:DESTI RS10570
gene id: 706587:DESTI_RS10570
uniprot id: I4C5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

706587:DESTI RS07820
gene id: 706587:DESTI_RS07820
uniprot id: I4C3Y2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

706587:DESTI RS01680
gene id: 706587:DESTI_RS01680
uniprot id: I4C0I2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

706587:DESTI RS23340
gene id: 706587:DESTI_RS23340
uniprot id: I4CCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

706587:DESTI RS27145
gene id: 706587:DESTI_RS27145
uniprot id: I4CER5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS02010
gene id: 706587:DESTI_RS02010
uniprot id: I4C0P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

706587:DESTI RS08185
gene id: 706587:DESTI_RS08185
uniprot id: I4C457
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS14530
gene id: 706587:DESTI_RS14530
uniprot id: I4C7P9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

706587:DESTI RS15990
gene id: 706587:DESTI_RS15990
uniprot id: I4C8H8
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

706587:DESTI RS12995
gene id: 706587:DESTI_RS12995
uniprot id: I4C6V0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

706587:DESTI RS26195
gene id: 706587:DESTI_RS26195
uniprot id: I4CE79
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

706587:DESTI RS24250
gene id: 706587:DESTI_RS24250
uniprot id: I4CD65
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS15280
gene id: 706587:DESTI_RS15280
uniprot id: I4C841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

706587:DESTI RS21745
gene id: 706587:DESTI_RS21745
uniprot id: I4CBS4
names: Similarity
messages: Belongs to the thioredoxin family.

706587:DESTI RS23710
gene id: 706587:DESTI_RS23710
uniprot id: I4CCW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS06335
gene id: 706587:DESTI_RS06335
uniprot id: I4C339
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

706587:DESTI RS17485
gene id: 706587:DESTI_RS17485
uniprot id: I4C9C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS05915
gene id: 706587:DESTI_RS05915
uniprot id: I4C2V8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

706587:DESTI RS20265
gene id: 706587:DESTI_RS20265
uniprot id: I4CAY0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

706587:DESTI RS23155
gene id: 706587:DESTI_RS23155
uniprot id: I4CCK4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS04790
gene id: 706587:DESTI_RS04790
uniprot id: I4C286
names: Similarity
messages: Belongs to the UPF0145 family.

706587:DESTI RS24130
gene id: 706587:DESTI_RS24130
uniprot id: I4CD42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

706587:DESTI RS23485
gene id: 706587:DESTI_RS23485
uniprot id: I4CCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

706587:DESTI RS22870
gene id: 706587:DESTI_RS22870
uniprot id: I4CCF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

706587:DESTI RS24100
gene id: 706587:DESTI_RS24100
uniprot id: I4CD36
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

706587:DESTI RS26175
gene id: 706587:DESTI_RS26175
uniprot id: I4CE75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

706587:DESTI RS15310
gene id: 706587:DESTI_RS15310
uniprot id: I4C847
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

706587:DESTI RS02150
gene id: 706587:DESTI_RS02150
uniprot id: I4C0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS02845
gene id: 706587:DESTI_RS02845
uniprot id: I4C160
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

706587:DESTI RS08195
gene id: 706587:DESTI_RS08195
uniprot id: I4C459
names: Subcellular Location Annotation
messages: Peroxisome

706587:DESTI RS09155
gene id: 706587:DESTI_RS09155
uniprot id: I4C4P6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

706587:DESTI RS15405
gene id: 706587:DESTI_RS15405
uniprot id: I4C866
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

706587:DESTI RS16510
gene id: 706587:DESTI_RS16510
uniprot id: I4C8T3
names: Similarity
messages: Belongs to the peptidase C40 family.

706587:DESTI RS27130
gene id: 706587:DESTI_RS27130
uniprot id: I4CER3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

706587:DESTI RS19735
gene id: 706587:DESTI_RS19735
uniprot id: I4CAM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

706587:DESTI RS10245
gene id: 706587:DESTI_RS10245
uniprot id: I4C5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

706587:DESTI RS18410
gene id: 706587:DESTI_RS18410
uniprot id: I4C9V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

706587:DESTI RS03950
gene id: 706587:DESTI_RS03950
uniprot id: I4C1S7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

706587:DESTI RS23575
gene id: 706587:DESTI_RS23575
uniprot id: I4CCT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS07840
gene id: 706587:DESTI_RS07840
uniprot id: I4C3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

706587:DESTI RS20910
gene id: 706587:DESTI_RS20910
uniprot id: I4CBB0
names: Similarity
messages: Belongs to the UPF0111 family.

706587:DESTI RS27400
gene id: 706587:DESTI_RS27400
uniprot id: I4CEW0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS06695
gene id: 706587:DESTI_RS06695
uniprot id: I4C3B2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

706587:DESTI RS12730
gene id: 706587:DESTI_RS12730
uniprot id: I4C6P3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

706587:DESTI RS11255
gene id: 706587:DESTI_RS11255
uniprot id: I4C5U8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS12470
gene id: 706587:DESTI_RS12470
uniprot id: I4C6I8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

706587:DESTI RS28615
gene id: 706587:DESTI_RS28615
uniprot id: I4C4H4
names: Similarity
messages: Belongs to the DtxR/MntR family.

706587:DESTI RS18630
gene id: 706587:DESTI_RS18630
uniprot id: I4CA01
names: Similarity
messages: Belongs to the Ahb/Nir family.

706587:DESTI RS06775
gene id: 706587:DESTI_RS06775
uniprot id: I4C3C9
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

706587:DESTI RS19215
gene id: 706587:DESTI_RS19215
uniprot id: I4CAB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

706587:DESTI RS27805
gene id: 706587:DESTI_RS27805
uniprot id: I4CF37
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS12275
gene id: 706587:DESTI_RS12275
uniprot id: I4C6F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

706587:DESTI RS27165
gene id: 706587:DESTI_RS27165
uniprot id: I4CER7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS26130
gene id: 706587:DESTI_RS26130
uniprot id: I4CE66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

706587:DESTI RS14905
gene id: 706587:DESTI_RS14905
uniprot id: I4C7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

706587:DESTI RS25010
gene id: 706587:DESTI_RS25010
uniprot id: I4CDL2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18650
gene id: 706587:DESTI_RS18650
uniprot id: I4CA05
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

706587:DESTI RS29470
gene id: 706587:DESTI_RS29470
uniprot id: I4CDP0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

706587:DESTI RS05995
gene id: 706587:DESTI_RS05995
uniprot id: I4C2X2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

706587:DESTI RS06460
gene id: 706587:DESTI_RS06460
uniprot id: I4C364
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

706587:DESTI RS27335
gene id: 706587:DESTI_RS27335
uniprot id: I4CEU7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00015
gene id: 706587:DESTI_RS00015
uniprot id: I4BZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

706587:DESTI RS23935
gene id: 706587:DESTI_RS23935
uniprot id: I4CD05
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

706587:DESTI RS12050
gene id: 706587:DESTI_RS12050
uniprot id: I4C6A4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS24140
gene id: 706587:DESTI_RS24140
uniprot id: I4CD44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

706587:DESTI RS05855
gene id: 706587:DESTI_RS05855
uniprot id: I4C2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS24600
gene id: 706587:DESTI_RS24600
uniprot id: I4CDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

706587:DESTI RS13575
gene id: 706587:DESTI_RS13575
uniprot id: I4C766
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

706587:DESTI RS05545
gene id: 706587:DESTI_RS05545
uniprot id: I4C2N5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

706587:DESTI RS26225
gene id: 706587:DESTI_RS26225
uniprot id: I4CE86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

706587:DESTI RS13965
gene id: 706587:DESTI_RS13965
uniprot id: I4C7D7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

706587:DESTI RS21260
gene id: 706587:DESTI_RS21260
uniprot id: I4CBH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

706587:DESTI RS21560
gene id: 706587:DESTI_RS21560
uniprot id: I4CBN9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS01720
gene id: 706587:DESTI_RS01720
uniprot id: I4C0I8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

706587:DESTI RS18625
gene id: 706587:DESTI_RS18625
uniprot id: I4CA00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS10565
gene id: 706587:DESTI_RS10565
uniprot id: I4C5G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

706587:DESTI RS10720
gene id: 706587:DESTI_RS10720
uniprot id: I4C5J4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS09270
gene id: 706587:DESTI_RS09270
uniprot id: I4C4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

706587:DESTI RS25215
gene id: 706587:DESTI_RS25215
uniprot id: I4CDQ2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS28115
gene id: 706587:DESTI_RS28115
uniprot id: I4CFA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

706587:DESTI RS24020
gene id: 706587:DESTI_RS24020
uniprot id: I4CD21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

706587:DESTI RS24500
gene id: 706587:DESTI_RS24500
uniprot id: I4CDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

706587:DESTI RS09060
gene id: 706587:DESTI_RS09060
uniprot id: I4C4M7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05885
gene id: 706587:DESTI_RS05885
uniprot id: I4C2V1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

706587:DESTI RS21275
gene id: 706587:DESTI_RS21275
uniprot id: I4CBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

706587:DESTI RS24870
gene id: 706587:DESTI_RS24870
uniprot id: I4CDI6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS15210
gene id: 706587:DESTI_RS15210
uniprot id: I4C830
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

706587:DESTI RS06145
gene id: 706587:DESTI_RS06145
uniprot id: I4C300
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

706587:DESTI RS27275
gene id: 706587:DESTI_RS27275
uniprot id: I4CET9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20080
gene id: 706587:DESTI_RS20080
uniprot id: I4CAU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

706587:DESTI RS08210
gene id: 706587:DESTI_RS08210
uniprot id: I4C463
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

706587:DESTI RS26420
gene id: 706587:DESTI_RS26420
uniprot id: I4CEC7
names: Subunit
messages: Heterodimer of a large and a small subunit.

706587:DESTI RS18965
gene id: 706587:DESTI_RS18965
uniprot id: I4CA65
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

706587:DESTI RS21690
gene id: 706587:DESTI_RS21690
uniprot id: I4CBR5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26235
gene id: 706587:DESTI_RS26235
uniprot id: I4CE88
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

706587:DESTI RS29100
gene id: 706587:DESTI_RS29100
uniprot id: I4C9H7
names: Subcellular Location Annotation
messages: Cell inner membrane

706587:DESTI RS06455
gene id: 706587:DESTI_RS06455
uniprot id: I4C363
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

706587:DESTI RS23585
gene id: 706587:DESTI_RS23585
uniprot id: I4CCT7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

706587:DESTI RS11820
gene id: 706587:DESTI_RS11820
uniprot id: I4C659
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05775
gene id: 706587:DESTI_RS05775
uniprot id: I4C2S9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

706587:DESTI RS07830
gene id: 706587:DESTI_RS07830
uniprot id: I4C3Y4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

706587:DESTI RS10650
gene id: 706587:DESTI_RS10650
uniprot id: I4C5I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

706587:DESTI RS03580
gene id: 706587:DESTI_RS03580
uniprot id: I4C1K5
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

706587:DESTI RS27415
gene id: 706587:DESTI_RS27415
uniprot id: I4CEW3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

706587:DESTI RS16730
gene id: 706587:DESTI_RS16730
uniprot id: I4C8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

706587:DESTI RS21035
gene id: 706587:DESTI_RS21035
uniprot id: I4CBD6
names: Similarity
messages: Belongs to the HepT RNase toxin family.

706587:DESTI RS14280
gene id: 706587:DESTI_RS14280
uniprot id: I4C7K0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

706587:DESTI RS08070
gene id: 706587:DESTI_RS08070
uniprot id: I4C433
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS27950
gene id: 706587:DESTI_RS27950
uniprot id: I4CF67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS16580
gene id: 706587:DESTI_RS16580
uniprot id: I4C8U7
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

706587:DESTI RS21025
gene id: 706587:DESTI_RS21025
uniprot id: I4CBD4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18465
gene id: 706587:DESTI_RS18465
uniprot id: I4C9W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

706587:DESTI RS05030
gene id: 706587:DESTI_RS05030
uniprot id: I4C2D5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS23520
gene id: 706587:DESTI_RS23520
uniprot id: I4CCS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

706587:DESTI RS28905
gene id: 706587:DESTI_RS28905
uniprot id: I4C7D4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS21065
gene id: 706587:DESTI_RS21065
uniprot id: I4CBE2
names: Similarity
messages: Belongs to the peptidase S58 family.

706587:DESTI RS02710
gene id: 706587:DESTI_RS02710
uniprot id: I4C138
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

706587:DESTI RS13070
gene id: 706587:DESTI_RS13070
uniprot id: I4C6W4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS02560
gene id: 706587:DESTI_RS02560
uniprot id: I4C104
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

706587:DESTI RS00515
gene id: 706587:DESTI_RS00515
uniprot id: I4BZV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

706587:DESTI RS21210
gene id: 706587:DESTI_RS21210
uniprot id: I4CBG7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

706587:DESTI RS14780
gene id: 706587:DESTI_RS14780
uniprot id: I4C7V0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

706587:DESTI RS07860
gene id: 706587:DESTI_RS07860
uniprot id: I4C3Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

706587:DESTI RS27725
gene id: 706587:DESTI_RS27725
uniprot id: I4CF22
names: Similarity
messages: Belongs to the CutA family.

706587:DESTI RS13730
gene id: 706587:DESTI_RS13730
uniprot id: I4C796
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS07125
gene id: 706587:DESTI_RS07125
uniprot id: I4C3J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

706587:DESTI RS15815
gene id: 706587:DESTI_RS15815
uniprot id: I4C8E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

706587:DESTI RS23540
gene id: 706587:DESTI_RS23540
uniprot id: I4CCS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS20415
gene id: 706587:DESTI_RS20415
uniprot id: I4CB12
names: Similarity
messages: Belongs to the TrpF family.

706587:DESTI RS13630
gene id: 706587:DESTI_RS13630
uniprot id: I4C776
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

706587:DESTI RS18655
gene id: 706587:DESTI_RS18655
uniprot id: I4CA06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

706587:DESTI RS03555
gene id: 706587:DESTI_RS03555
uniprot id: I4C1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS13385
gene id: 706587:DESTI_RS13385
uniprot id: I4C729
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS01670
gene id: 706587:DESTI_RS01670
uniprot id: I4C0I0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

706587:DESTI RS05760
gene id: 706587:DESTI_RS05760
uniprot id: I4C2S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

706587:DESTI RS23905
gene id: 706587:DESTI_RS23905
uniprot id: I4CCZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

706587:DESTI RS18050
gene id: 706587:DESTI_RS18050
uniprot id: I4C9N3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS08610
gene id: 706587:DESTI_RS08610
uniprot id: I4C4E1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS01815
gene id: 706587:DESTI_RS01815
uniprot id: I4C0K7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS18505
gene id: 706587:DESTI_RS18505
uniprot id: I4C9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

706587:DESTI RS20200
gene id: 706587:DESTI_RS20200
uniprot id: I4CAW9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS21945
gene id: 706587:DESTI_RS21945
uniprot id: I4CBW4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

706587:DESTI RS23775
gene id: 706587:DESTI_RS23775
uniprot id: I4CCX4
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

706587:DESTI RS04380
gene id: 706587:DESTI_RS04380
uniprot id: I4C209
names: Similarity
messages: Belongs to the MtrH family.

706587:DESTI RS26160
gene id: 706587:DESTI_RS26160
uniprot id: I4CE72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

706587:DESTI RS18530
gene id: 706587:DESTI_RS18530
uniprot id: I4C9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

706587:DESTI RS07060
gene id: 706587:DESTI_RS07060
uniprot id: I4C3I6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

706587:DESTI RS12905
gene id: 706587:DESTI_RS12905
uniprot id: I4C6S9
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

706587:DESTI RS12815
gene id: 706587:DESTI_RS12815
uniprot id: I4C6R1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS00665
gene id: 706587:DESTI_RS00665
uniprot id: I4BZY7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

706587:DESTI RS01825
gene id: 706587:DESTI_RS01825
uniprot id: I4C0K9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

706587:DESTI RS03970
gene id: 706587:DESTI_RS03970
uniprot id: I4C1T1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

706587:DESTI RS14565
gene id: 706587:DESTI_RS14565
uniprot id: I4C7Q6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

706587:DESTI RS15330
gene id: 706587:DESTI_RS15330
uniprot id: I4C851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

706587:DESTI RS23550
gene id: 706587:DESTI_RS23550
uniprot id: I4CCT0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS14460
gene id: 706587:DESTI_RS14460
uniprot id: I4C7N3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS13985
gene id: 706587:DESTI_RS13985
uniprot id: I4C7E1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

706587:DESTI RS27975
gene id: 706587:DESTI_RS27975
uniprot id: I4CF72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

706587:DESTI RS03815
gene id: 706587:DESTI_RS03815
uniprot id: I4C1Q0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS23160
gene id: 706587:DESTI_RS23160
uniprot id: I4CCK5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS21455
gene id: 706587:DESTI_RS21455
uniprot id: I4CBL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

706587:DESTI RS08460
gene id: 706587:DESTI_RS08460
uniprot id: I4C4B2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS02350
gene id: 706587:DESTI_RS02350
uniprot id: I4C0W5
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

706587:DESTI RS05415
gene id: 706587:DESTI_RS05415
uniprot id: I4C2K9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

706587:DESTI RS21715
gene id: 706587:DESTI_RS21715
uniprot id: I4CBR9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

706587:DESTI RS09980
gene id: 706587:DESTI_RS09980
uniprot id: I4C557
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS27505
gene id: 706587:DESTI_RS27505
uniprot id: I4CEX9
names: Similarity
messages: Belongs to the class-I fumarase family.

706587:DESTI RS18725
gene id: 706587:DESTI_RS18725
uniprot id: I4CA21
names: Similarity
messages: Belongs to the NodU/CmcH family.

706587:DESTI RS01625
gene id: 706587:DESTI_RS01625
uniprot id: I4C0H0
names: Similarity
messages: Belongs to the YggT family.

706587:DESTI RS11265
gene id: 706587:DESTI_RS11265
uniprot id: I4C5V0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS09695
gene id: 706587:DESTI_RS09695
uniprot id: I4C504
names: Similarity
messages: Belongs to the AOR/FOR family.

706587:DESTI RS07580
gene id: 706587:DESTI_RS07580
uniprot id: I4C3T8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS26120
gene id: 706587:DESTI_RS26120
uniprot id: I4CE64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

706587:DESTI RS15520
gene id: 706587:DESTI_RS15520
uniprot id: I4C888
names: Similarity
messages: Belongs to the Skp family.

706587:DESTI RS23110
gene id: 706587:DESTI_RS23110
uniprot id: I4CCJ7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

706587:DESTI RS14555
gene id: 706587:DESTI_RS14555
uniprot id: I4C7Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

706587:DESTI RS09130
gene id: 706587:DESTI_RS09130
uniprot id: I4C4P1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS08575
gene id: 706587:DESTI_RS08575
uniprot id: I4C4D5
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

706587:DESTI RS24495
gene id: 706587:DESTI_RS24495
uniprot id: I4CDB0
names: Similarity
messages: Belongs to the AAA ATPase family.

706587:DESTI RS13000
gene id: 706587:DESTI_RS13000
uniprot id: I4C6V1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

706587:DESTI RS25820
gene id: 706587:DESTI_RS25820
uniprot id: I4CE12
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

706587:DESTI RS11070
gene id: 706587:DESTI_RS11070
uniprot id: I4C5Q9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

706587:DESTI RS13080
gene id: 706587:DESTI_RS13080
uniprot id: I4C6W6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

706587:DESTI RS24505
gene id: 706587:DESTI_RS24505
uniprot id: I4CDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

706587:DESTI RS01115
gene id: 706587:DESTI_RS01115
uniprot id: I4C077
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

706587:DESTI RS15500
gene id: 706587:DESTI_RS15500
uniprot id: I4C884
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26685
gene id: 706587:DESTI_RS26685
uniprot id: I4CEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

706587:DESTI RS03565
gene id: 706587:DESTI_RS03565
uniprot id: I4C1K2
names: Similarity
messages: Belongs to the peptidase S16 family.

706587:DESTI RS05070
gene id: 706587:DESTI_RS05070
uniprot id: I4C2E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

706587:DESTI RS13980
gene id: 706587:DESTI_RS13980
uniprot id: I4C7E0
names: Similarity
messages: Belongs to the asparagine synthetase family.

706587:DESTI RS01895
gene id: 706587:DESTI_RS01895
uniprot id: I4C0M3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

706587:DESTI RS12935
gene id: 706587:DESTI_RS12935
uniprot id: I4C6T5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

706587:DESTI RS13520
gene id: 706587:DESTI_RS13520
uniprot id: I4C755
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS16650
gene id: 706587:DESTI_RS16650
uniprot id: I4C8W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

706587:DESTI RS11140
gene id: 706587:DESTI_RS11140
uniprot id: I4C5S3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS28140
gene id: 706587:DESTI_RS28140
uniprot id: I4CFA5
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

706587:DESTI RS23345
gene id: 706587:DESTI_RS23345
uniprot id: I4CCP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

706587:DESTI RS07425
gene id: 706587:DESTI_RS07425
uniprot id: I4C3Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

706587:DESTI RS18455
gene id: 706587:DESTI_RS18455
uniprot id: I4C9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

706587:DESTI RS22030
gene id: 706587:DESTI_RS22030
uniprot id: I4CBY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS14470
gene id: 706587:DESTI_RS14470
uniprot id: I4C7N5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

706587:DESTI RS00955
gene id: 706587:DESTI_RS00955
uniprot id: I4C047
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

706587:DESTI RS08365
gene id: 706587:DESTI_RS08365
uniprot id: I4C494
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

706587:DESTI RS18010
gene id: 706587:DESTI_RS18010
uniprot id: I4C9M5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS28895
gene id: 706587:DESTI_RS28895
uniprot id: I4C772
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

706587:DESTI RS22200
gene id: 706587:DESTI_RS22200
uniprot id: I4CC19
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS11175
gene id: 706587:DESTI_RS11175
uniprot id: I4C5T1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

706587:DESTI RS19195
gene id: 706587:DESTI_RS19195
uniprot id: I4CAB3
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

706587:DESTI RS02060
gene id: 706587:DESTI_RS02060
uniprot id: I4C0Q5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26185
gene id: 706587:DESTI_RS26185
uniprot id: I4CE77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

706587:DESTI RS06655
gene id: 706587:DESTI_RS06655
uniprot id: I4C3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS18905
gene id: 706587:DESTI_RS18905
uniprot id: I4CA53
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

706587:DESTI RS19965
gene id: 706587:DESTI_RS19965
uniprot id: I4CAS2
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

706587:DESTI RS01935
gene id: 706587:DESTI_RS01935
uniprot id: I4C0N2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS08615
gene id: 706587:DESTI_RS08615
uniprot id: I4C4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

706587:DESTI RS19165
gene id: 706587:DESTI_RS19165
uniprot id: I4CAA7
names: Similarity
messages: Belongs to the HdrA family.

706587:DESTI RS01845
gene id: 706587:DESTI_RS01845
uniprot id: I4C0L3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

706587:DESTI RS19460
gene id: 706587:DESTI_RS19460
uniprot id: I4CAG7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS24965
gene id: 706587:DESTI_RS24965
uniprot id: I4CDK3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

706587:DESTI RS10870
gene id: 706587:DESTI_RS10870
uniprot id: I4C5M3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

706587:DESTI RS15995
gene id: 706587:DESTI_RS15995
uniprot id: I4C8H9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS07865
gene id: 706587:DESTI_RS07865
uniprot id: I4C3Z2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

706587:DESTI RS06430
gene id: 706587:DESTI_RS06430
uniprot id: I4C358
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

706587:DESTI RS26125
gene id: 706587:DESTI_RS26125
uniprot id: I4CE65
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

706587:DESTI RS19960
gene id: 706587:DESTI_RS19960
uniprot id: I4CAS1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

706587:DESTI RS09960
gene id: 706587:DESTI_RS09960
uniprot id: I4C553
names: Similarity
messages: Belongs to the universal stress protein A family.

706587:DESTI RS00030
gene id: 706587:DESTI_RS00030
uniprot id: I4BZL4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

706587:DESTI RS19720
gene id: 706587:DESTI_RS19720
uniprot id: I4CAM3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

706587:DESTI RS03165
gene id: 706587:DESTI_RS03165
uniprot id: I4C1C3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06660
gene id: 706587:DESTI_RS06660
uniprot id: I4C3A3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS09515
gene id: 706587:DESTI_RS09515
uniprot id: I4C4X0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS17935
gene id: 706587:DESTI_RS17935
uniprot id: I4C9L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS00950
gene id: 706587:DESTI_RS00950
uniprot id: I4C045
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS19520
gene id: 706587:DESTI_RS19520
uniprot id: I4CAH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

706587:DESTI RS05660
gene id: 706587:DESTI_RS05660
uniprot id: I4C2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

706587:DESTI RS14685
gene id: 706587:DESTI_RS14685
uniprot id: I4C7T0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS27115
gene id: 706587:DESTI_RS27115
uniprot id: I4CER0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

706587:DESTI RS01365
gene id: 706587:DESTI_RS01365
uniprot id: I4C0C3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

706587:DESTI RS20735
gene id: 706587:DESTI_RS20735
uniprot id: I4CB76
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

706587:DESTI RS12990
gene id: 706587:DESTI_RS12990
uniprot id: I4C6U8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

706587:DESTI RS10370
gene id: 706587:DESTI_RS10370
uniprot id: I4C5D2
names: Similarity
messages: Belongs to the universal stress protein A family.

706587:DESTI RS15335
gene id: 706587:DESTI_RS15335
uniprot id: I4C852
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

706587:DESTI RS26280
gene id: 706587:DESTI_RS26280
uniprot id: I4CE97
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

706587:DESTI RS06625
gene id: 706587:DESTI_RS06625
uniprot id: I4C397
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

706587:DESTI RS08010
gene id: 706587:DESTI_RS08010
uniprot id: I4C420
names: Similarity
messages: Belongs to the asparagine synthetase family.

706587:DESTI RS03500
gene id: 706587:DESTI_RS03500
uniprot id: I4C1I9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS22100
gene id: 706587:DESTI_RS22100
uniprot id: I4CBZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

706587:DESTI RS27225
gene id: 706587:DESTI_RS27225
uniprot id: I4CES9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

706587:DESTI RS08200
gene id: 706587:DESTI_RS08200
uniprot id: I4C460
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

706587:DESTI RS18565
gene id: 706587:DESTI_RS18565
uniprot id: I4C9Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS29225
gene id: 706587:DESTI_RS29225
uniprot id: I4CBB5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

706587:DESTI RS16195
gene id: 706587:DESTI_RS16195
uniprot id: I4C8L8
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

706587:DESTI RS17945
gene id: 706587:DESTI_RS17945
uniprot id: I4C9L4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

706587:DESTI RS07320
gene id: 706587:DESTI_RS07320
uniprot id: I4C3N5
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

706587:DESTI RS18025
gene id: 706587:DESTI_RS18025
uniprot id: I4C9M8
names: Similarity
messages: Belongs to the AHA1 family.

706587:DESTI RS20120
gene id: 706587:DESTI_RS20120
uniprot id: I4CAV3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

706587:DESTI RS24450
gene id: 706587:DESTI_RS24450
uniprot id: I4CDA3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS10495
gene id: 706587:DESTI_RS10495
uniprot id: I4C5F3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05400
gene id: 706587:DESTI_RS05400
uniprot id: I4C2K7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

706587:DESTI RS12285
gene id: 706587:DESTI_RS12285
uniprot id: I4C6F3
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

706587:DESTI RS07065
gene id: 706587:DESTI_RS07065
uniprot id: I4C3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

706587:DESTI RS14710
gene id: 706587:DESTI_RS14710
uniprot id: I4C7T5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

706587:DESTI RS19560
gene id: 706587:DESTI_RS19560
uniprot id: I4CAJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS01635
gene id: 706587:DESTI_RS01635
uniprot id: I4C0H2
names: Similarity
messages: Belongs to the UbiD family.

706587:DESTI RS07920
gene id: 706587:DESTI_RS07920
uniprot id: I4C403
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

706587:DESTI RS13050
gene id: 706587:DESTI_RS13050
uniprot id: I4C6W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

706587:DESTI RS10820
gene id: 706587:DESTI_RS10820
uniprot id: I4C5L4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

706587:DESTI RS21815
gene id: 706587:DESTI_RS21815
uniprot id: I4CBT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

706587:DESTI RS21700
gene id: 706587:DESTI_RS21700
uniprot id: I4CBR7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS07595
gene id: 706587:DESTI_RS07595
uniprot id: I4C3U1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20420
gene id: 706587:DESTI_RS20420
uniprot id: I4CB13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

706587:DESTI RS20030
gene id: 706587:DESTI_RS20030
uniprot id: I4CAT5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

706587:DESTI RS01930
gene id: 706587:DESTI_RS01930
uniprot id: I4C0N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS05685
gene id: 706587:DESTI_RS05685
uniprot id: I4C2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

706587:DESTI RS18450
gene id: 706587:DESTI_RS18450
uniprot id: I4C9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

706587:DESTI RS00430
gene id: 706587:DESTI_RS00430
uniprot id: I4BZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TolB family.
messages: Periplasm

706587:DESTI RS27770
gene id: 706587:DESTI_RS27770
uniprot id: I4CF31
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

706587:DESTI RS19710
gene id: 706587:DESTI_RS19710
uniprot id: I4CAM1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS13760
gene id: 706587:DESTI_RS13760
uniprot id: I4C7A2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

706587:DESTI RS24220
gene id: 706587:DESTI_RS24220
uniprot id: I4CD59
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS23335
gene id: 706587:DESTI_RS23335
uniprot id: I4CCN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS27090
gene id: 706587:DESTI_RS27090
uniprot id: I4CEQ5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

706587:DESTI RS08000
gene id: 706587:DESTI_RS08000
uniprot id: I4C419
names: Similarity
messages: Belongs to the AOR/FOR family.

706587:DESTI RS08630
gene id: 706587:DESTI_RS08630
uniprot id: I4C4E5
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS12830
gene id: 706587:DESTI_RS12830
uniprot id: I4C6R4
names: Similarity
messages: Belongs to the CinA family.

706587:DESTI RS27985
gene id: 706587:DESTI_RS27985
uniprot id: I4CF74
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06110
gene id: 706587:DESTI_RS06110
uniprot id: I4C2Z3
names: Similarity
messages: Belongs to the peptidase M18 family.

706587:DESTI RS20585
gene id: 706587:DESTI_RS20585
uniprot id: I4CB47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

706587:DESTI RS08155
gene id: 706587:DESTI_RS08155
uniprot id: I4C451
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

706587:DESTI RS27065
gene id: 706587:DESTI_RS27065
uniprot id: I4CEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

706587:DESTI RS08355
gene id: 706587:DESTI_RS08355
uniprot id: I4C492
names: Similarity
messages: Belongs to the UPF0047 family.

706587:DESTI RS25550
gene id: 706587:DESTI_RS25550
uniprot id: I4CDW4
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

706587:DESTI RS27100
gene id: 706587:DESTI_RS27100
uniprot id: I4CEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS20560
gene id: 706587:DESTI_RS20560
uniprot id: I4CB41
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS26625
gene id: 706587:DESTI_RS26625
uniprot id: I4CEG8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20195
gene id: 706587:DESTI_RS20195
uniprot id: I4CAW8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS12835
gene id: 706587:DESTI_RS12835
uniprot id: I4C6R5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

706587:DESTI RS17500
gene id: 706587:DESTI_RS17500
uniprot id: I4C9C8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

706587:DESTI RS20425
gene id: 706587:DESTI_RS20425
uniprot id: I4CB14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

706587:DESTI RS16285
gene id: 706587:DESTI_RS16285
uniprot id: I4C8N5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

706587:DESTI RS18380
gene id: 706587:DESTI_RS18380
uniprot id: I4C9V0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00980
gene id: 706587:DESTI_RS00980
uniprot id: I4C052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

706587:DESTI RS21085
gene id: 706587:DESTI_RS21085
uniprot id: I4CBE6
names: Similarity
messages: Belongs to the peptidase S16 family.

706587:DESTI RS14695
gene id: 706587:DESTI_RS14695
uniprot id: I4C7T2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS14220
gene id: 706587:DESTI_RS14220
uniprot id: I4C7I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

706587:DESTI RS27970
gene id: 706587:DESTI_RS27970
uniprot id: I4CF71
names: Similarity
messages: Belongs to the CFA/CMAS family.

706587:DESTI RS17930
gene id: 706587:DESTI_RS17930
uniprot id: I4C9L1
names: Similarity
messages: Belongs to the P(II) protein family.

706587:DESTI RS04670
gene id: 706587:DESTI_RS04670
uniprot id: I4C260
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS15320
gene id: 706587:DESTI_RS15320
uniprot id: I4C849
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

706587:DESTI RS01820
gene id: 706587:DESTI_RS01820
uniprot id: I4C0K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

706587:DESTI RS18700
gene id: 706587:DESTI_RS18700
uniprot id: I4CA15
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS04780
gene id: 706587:DESTI_RS04780
uniprot id: I4C284
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

706587:DESTI RS02065
gene id: 706587:DESTI_RS02065
uniprot id: I4C0Q6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS11165
gene id: 706587:DESTI_RS11165
uniprot id: I4C5S9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06295
gene id: 706587:DESTI_RS06295
uniprot id: I4C331
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS08950
gene id: 706587:DESTI_RS08950
uniprot id: I4C4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

706587:DESTI RS25540
gene id: 706587:DESTI_RS25540
uniprot id: I4CDW2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26145
gene id: 706587:DESTI_RS26145
uniprot id: I4CE69
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

706587:DESTI RS05220
gene id: 706587:DESTI_RS05220
uniprot id: I4C2H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

706587:DESTI RS00885
gene id: 706587:DESTI_RS00885
uniprot id: I4C031
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

706587:DESTI RS08435
gene id: 706587:DESTI_RS08435
uniprot id: I4C4A7
names: Similarity
messages: Belongs to the disproportionating enzyme family.

706587:DESTI RS09675
gene id: 706587:DESTI_RS09675
uniprot id: I4C500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS23685
gene id: 706587:DESTI_RS23685
uniprot id: I4CCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

706587:DESTI RS30890
gene id: 706587:DESTI_RS30890
uniprot id: I4CAI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

706587:DESTI RS18425
gene id: 706587:DESTI_RS18425
uniprot id: I4C9V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

706587:DESTI RS00775
gene id: 706587:DESTI_RS00775
uniprot id: I4C010
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

706587:DESTI RS14870
gene id: 706587:DESTI_RS14870
uniprot id: I4C7W4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

706587:DESTI RS00300
gene id: 706587:DESTI_RS00300
uniprot id: I4BZR8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

706587:DESTI RS05420
gene id: 706587:DESTI_RS05420
uniprot id: I4C2L0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

706587:DESTI RS14910
gene id: 706587:DESTI_RS14910
uniprot id: I4C7X2
names: Similarity
messages: Belongs to the aspartokinase family.

706587:DESTI RS02020
gene id: 706587:DESTI_RS02020
uniprot id: I4C0P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

706587:DESTI RS11630
gene id: 706587:DESTI_RS11630
uniprot id: I4C623
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

706587:DESTI RS12860
gene id: 706587:DESTI_RS12860
uniprot id: I4C6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

706587:DESTI RS22880
gene id: 706587:DESTI_RS22880
uniprot id: I4CCF4
names: Similarity
messages: Belongs to the peptidase S49 family.

706587:DESTI RS26075
gene id: 706587:DESTI_RS26075
uniprot id: I4CE54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

706587:DESTI RS16275
gene id: 706587:DESTI_RS16275
uniprot id: I4C8N4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

706587:DESTI RS29575
gene id: 706587:DESTI_RS29575
uniprot id: I4CEW8
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

706587:DESTI RS17700
gene id: 706587:DESTI_RS17700
uniprot id: I4C9G7
names: Similarity
messages: Belongs to the hemerythrin family.

706587:DESTI RS02415
gene id: 706587:DESTI_RS02415
uniprot id: I4C0X7
names: Similarity
messages: Belongs to the hemerythrin family.

706587:DESTI RS05155
gene id: 706587:DESTI_RS05155
uniprot id: I4C2G0
names: Similarity
messages: Belongs to the fabD family.

706587:DESTI RS27075
gene id: 706587:DESTI_RS27075
uniprot id: I4CEQ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS08635
gene id: 706587:DESTI_RS08635
uniprot id: I4C4E7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

706587:DESTI RS16155
gene id: 706587:DESTI_RS16155
uniprot id: I4C8L0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20955
gene id: 706587:DESTI_RS20955
uniprot id: I4CBC0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

706587:DESTI RS23490
gene id: 706587:DESTI_RS23490
uniprot id: I4CCR9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

706587:DESTI RS05730
gene id: 706587:DESTI_RS05730
uniprot id: I4C2S0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS13625
gene id: 706587:DESTI_RS13625
uniprot id: I4C775
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

706587:DESTI RS01350
gene id: 706587:DESTI_RS01350
uniprot id: I4C0C0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS06610
gene id: 706587:DESTI_RS06610
uniprot id: I4C394
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

706587:DESTI RS15450
gene id: 706587:DESTI_RS15450
uniprot id: I4C874
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS23170
gene id: 706587:DESTI_RS23170
uniprot id: I4CCK7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18475
gene id: 706587:DESTI_RS18475
uniprot id: I4C9W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

706587:DESTI RS16675
gene id: 706587:DESTI_RS16675
uniprot id: I4C8W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

706587:DESTI RS18075
gene id: 706587:DESTI_RS18075
uniprot id: I4C9N8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS13270
gene id: 706587:DESTI_RS13270
uniprot id: I4C707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

706587:DESTI RS23675
gene id: 706587:DESTI_RS23675
uniprot id: I4CCV5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS13200
gene id: 706587:DESTI_RS13200
uniprot id: I4C6Z2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS03465
gene id: 706587:DESTI_RS03465
uniprot id: I4C1I3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05575
gene id: 706587:DESTI_RS05575
uniprot id: I4C2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

706587:DESTI RS27870
gene id: 706587:DESTI_RS27870
uniprot id: I4CF50
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

706587:DESTI RS12655
gene id: 706587:DESTI_RS12655
uniprot id: I4C6M5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

706587:DESTI RS10795
gene id: 706587:DESTI_RS10795
uniprot id: I4C5L0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS01790
gene id: 706587:DESTI_RS01790
uniprot id: I4C0K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

706587:DESTI RS22785
gene id: 706587:DESTI_RS22785
uniprot id: I4CCD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

706587:DESTI RS04200
gene id: 706587:DESTI_RS04200
uniprot id: I4C1X7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS07660
gene id: 706587:DESTI_RS07660
uniprot id: I4C3V2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

706587:DESTI RS18785
gene id: 706587:DESTI_RS18785
uniprot id: I4CA31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

706587:DESTI RS27955
gene id: 706587:DESTI_RS27955
uniprot id: I4CF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS25165
gene id: 706587:DESTI_RS25165
uniprot id: I4CDP3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

706587:DESTI RS24415
gene id: 706587:DESTI_RS24415
uniprot id: I4CD96
names: Similarity
messages: Belongs to the UxaA family.

706587:DESTI RS02365
gene id: 706587:DESTI_RS02365
uniprot id: I4C0W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

706587:DESTI RS27325
gene id: 706587:DESTI_RS27325
uniprot id: I4CEU5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS18805
gene id: 706587:DESTI_RS18805
uniprot id: I4CA34
names: Similarity
messages: Belongs to the TrpF family.

706587:DESTI RS26485
gene id: 706587:DESTI_RS26485
uniprot id: I4CEE1
names: Similarity
messages: Belongs to the ELP3 family.

706587:DESTI RS04885
gene id: 706587:DESTI_RS04885
uniprot id: I4C2A4
names: Similarity
messages: Belongs to the UPF0145 family.

706587:DESTI RS09190
gene id: 706587:DESTI_RS09190
uniprot id: I4C4Q3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

706587:DESTI RS26165
gene id: 706587:DESTI_RS26165
uniprot id: I4CE73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

706587:DESTI RS12330
gene id: 706587:DESTI_RS12330
uniprot id: I4C6G2
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

706587:DESTI RS11190
gene id: 706587:DESTI_RS11190
uniprot id: I4C5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

706587:DESTI RS03065
gene id: 706587:DESTI_RS03065
uniprot id: I4C1A3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

706587:DESTI RS15395
gene id: 706587:DESTI_RS15395
uniprot id: I4C864
names: Similarity
messages: Belongs to the MEMO1 family.

706587:DESTI RS26105
gene id: 706587:DESTI_RS26105
uniprot id: I4CE61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

706587:DESTI RS14445
gene id: 706587:DESTI_RS14445
uniprot id: I4C7N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

706587:DESTI RS03985
gene id: 706587:DESTI_RS03985
uniprot id: I4C1T5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

706587:DESTI RS24990
gene id: 706587:DESTI_RS24990
uniprot id: I4CDK8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS24260
gene id: 706587:DESTI_RS24260
uniprot id: I4CD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS15725
gene id: 706587:DESTI_RS15725
uniprot id: I4C8C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

706587:DESTI RS18545
gene id: 706587:DESTI_RS18545
uniprot id: I4C9Y2
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

706587:DESTI RS21670
gene id: 706587:DESTI_RS21670
uniprot id: I4CBR1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00575
gene id: 706587:DESTI_RS00575
uniprot id: I4BZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS05250
gene id: 706587:DESTI_RS05250
uniprot id: I4C2I1
names: Similarity
messages: Belongs to the group II decarboxylase family.

706587:DESTI RS25780
gene id: 706587:DESTI_RS25780
uniprot id: I4CE05
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS22070
gene id: 706587:DESTI_RS22070
uniprot id: I4CBZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

706587:DESTI RS25130
gene id: 706587:DESTI_RS25130
uniprot id: I4CDN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

706587:DESTI RS07620
gene id: 706587:DESTI_RS07620
uniprot id: I4C3U5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

706587:DESTI RS21205
gene id: 706587:DESTI_RS21205
uniprot id: I4CBG6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

706587:DESTI RS10175
gene id: 706587:DESTI_RS10175
uniprot id: I4C595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

706587:DESTI RS14240
gene id: 706587:DESTI_RS14240
uniprot id: I4C7J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS26305
gene id: 706587:DESTI_RS26305
uniprot id: I4CEA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

706587:DESTI RS02155
gene id: 706587:DESTI_RS02155
uniprot id: I4C0S4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS09340
gene id: 706587:DESTI_RS09340
uniprot id: I4C4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

706587:DESTI RS18040
gene id: 706587:DESTI_RS18040
uniprot id: I4C9N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

706587:DESTI RS06890
gene id: 706587:DESTI_RS06890
uniprot id: I4C3F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS21940
gene id: 706587:DESTI_RS21940
uniprot id: I4CBW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS17625
gene id: 706587:DESTI_RS17625
uniprot id: I4C9F3
names: Similarity
messages: Belongs to the PstS family.

706587:DESTI RS13715
gene id: 706587:DESTI_RS13715
uniprot id: I4C793
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS07315
gene id: 706587:DESTI_RS07315
uniprot id: I4C3N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

706587:DESTI RS06330
gene id: 706587:DESTI_RS06330
uniprot id: I4C338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

706587:DESTI RS02580
gene id: 706587:DESTI_RS02580
uniprot id: I4C108
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS27320
gene id: 706587:DESTI_RS27320
uniprot id: I4CEU4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS09955
gene id: 706587:DESTI_RS09955
uniprot id: I4C552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

706587:DESTI RS21765
gene id: 706587:DESTI_RS21765
uniprot id: I4CBS8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05965
gene id: 706587:DESTI_RS05965
uniprot id: I4C2W8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05410
gene id: 706587:DESTI_RS05410
uniprot id: I4C2K8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS03290
gene id: 706587:DESTI_RS03290
uniprot id: I4C1E9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26065
gene id: 706587:DESTI_RS26065
uniprot id: I4CE52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

706587:DESTI RS08710
gene id: 706587:DESTI_RS08710
uniprot id: I4C4G0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS27795
gene id: 706587:DESTI_RS27795
uniprot id: I4CF36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

706587:DESTI RS14625
gene id: 706587:DESTI_RS14625
uniprot id: I4C7R8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

706587:DESTI RS18755
gene id: 706587:DESTI_RS18755
uniprot id: I4CA26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

706587:DESTI RS17025
gene id: 706587:DESTI_RS17025
uniprot id: I4C937
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

706587:DESTI RS00045
gene id: 706587:DESTI_RS00045
uniprot id: I4BZL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

706587:DESTI RS06000
gene id: 706587:DESTI_RS06000
uniprot id: I4C2X3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

706587:DESTI RS24535
gene id: 706587:DESTI_RS24535
uniprot id: I4CDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

706587:DESTI RS27540
gene id: 706587:DESTI_RS27540
uniprot id: I4CEY7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS07800
gene id: 706587:DESTI_RS07800
uniprot id: I4C3X8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

706587:DESTI RS18370
gene id: 706587:DESTI_RS18370
uniprot id: I4C9U8
names: Similarity
messages: Belongs to the leucine-binding protein family.

706587:DESTI RS10010
gene id: 706587:DESTI_RS10010
uniprot id: I4C563
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS07100
gene id: 706587:DESTI_RS07100
uniprot id: I4C3J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

706587:DESTI RS12490
gene id: 706587:DESTI_RS12490
uniprot id: I4C6J2
names: Similarity
messages: Belongs to the sulfatase family.

706587:DESTI RS01915
gene id: 706587:DESTI_RS01915
uniprot id: I4C0M8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS25545
gene id: 706587:DESTI_RS25545
uniprot id: I4CDW3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06060
gene id: 706587:DESTI_RS06060
uniprot id: I4C2Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS13725
gene id: 706587:DESTI_RS13725
uniprot id: I4C795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

706587:DESTI RS22575
gene id: 706587:DESTI_RS22575
uniprot id: I4CC96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

706587:DESTI RS18510
gene id: 706587:DESTI_RS18510
uniprot id: I4C9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

706587:DESTI RS29525
gene id: 706587:DESTI_RS29525
uniprot id: I4CEB8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

706587:DESTI RS20710
gene id: 706587:DESTI_RS20710
uniprot id: I4CB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

706587:DESTI RS29260
gene id: 706587:DESTI_RS29260
uniprot id: I4CBM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Membrane

706587:DESTI RS14295
gene id: 706587:DESTI_RS14295
uniprot id: I4C7K3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

706587:DESTI RS04595
gene id: 706587:DESTI_RS04595
uniprot id: I4C245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS04535
gene id: 706587:DESTI_RS04535
uniprot id: I4C233
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS02305
gene id: 706587:DESTI_RS02305
uniprot id: I4C0V6
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS04875
gene id: 706587:DESTI_RS04875
uniprot id: I4C2A2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18495
gene id: 706587:DESTI_RS18495
uniprot id: I4C9X3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS23545
gene id: 706587:DESTI_RS23545
uniprot id: I4CCS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

706587:DESTI RS03320
gene id: 706587:DESTI_RS03320
uniprot id: I4C1F4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS03600
gene id: 706587:DESTI_RS03600
uniprot id: I4C1K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

706587:DESTI RS20565
gene id: 706587:DESTI_RS20565
uniprot id: I4CB42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

706587:DESTI RS23590
gene id: 706587:DESTI_RS23590
uniprot id: I4CCT8
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS08505
gene id: 706587:DESTI_RS08505
uniprot id: I4C4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

706587:DESTI RS15475
gene id: 706587:DESTI_RS15475
uniprot id: I4C879
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

706587:DESTI RS12065
gene id: 706587:DESTI_RS12065
uniprot id: I4C6A7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS11725
gene id: 706587:DESTI_RS11725
uniprot id: I4C641
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

706587:DESTI RS15315
gene id: 706587:DESTI_RS15315
uniprot id: I4C848
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

706587:DESTI RS23755
gene id: 706587:DESTI_RS23755
uniprot id: I4CCX0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS28365
gene id: 706587:DESTI_RS28365
uniprot id: I4C1H8
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

706587:DESTI RS13225
gene id: 706587:DESTI_RS13225
uniprot id: I4C6Z6
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

706587:DESTI RS09160
gene id: 706587:DESTI_RS09160
uniprot id: I4C4P7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS07490
gene id: 706587:DESTI_RS07490
uniprot id: I4C3R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

706587:DESTI RS13860
gene id: 706587:DESTI_RS13860
uniprot id: I4C7B7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

706587:DESTI RS29160
gene id: 706587:DESTI_RS29160
uniprot id: I4CAG2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18620
gene id: 706587:DESTI_RS18620
uniprot id: I4C9Z9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

706587:DESTI RS18520
gene id: 706587:DESTI_RS18520
uniprot id: I4C9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

706587:DESTI RS19085
gene id: 706587:DESTI_RS19085
uniprot id: I4CA90
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

706587:DESTI RS24025
gene id: 706587:DESTI_RS24025
uniprot id: I4CD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

706587:DESTI RS21045
gene id: 706587:DESTI_RS21045
uniprot id: I4CBD8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

706587:DESTI RS22405
gene id: 706587:DESTI_RS22405
uniprot id: I4CC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

706587:DESTI RS11735
gene id: 706587:DESTI_RS11735
uniprot id: I4C643
names: Similarity
messages: Belongs to the histone deacetylase family.

706587:DESTI RS10090
gene id: 706587:DESTI_RS10090
uniprot id: I4C579
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS24305
gene id: 706587:DESTI_RS24305
uniprot id: I4CD76
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

706587:DESTI RS01630
gene id: 706587:DESTI_RS01630
uniprot id: I4C0H1
names: Similarity
messages: Belongs to the UPF0235 family.

706587:DESTI RS17970
gene id: 706587:DESTI_RS17970
uniprot id: I4C9L8
names: Similarity
messages: Belongs to the asparagine synthetase family.

706587:DESTI RS04025
gene id: 706587:DESTI_RS04025
uniprot id: I4C1U4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS19440
gene id: 706587:DESTI_RS19440
uniprot id: I4CAG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

706587:DESTI RS18985
gene id: 706587:DESTI_RS18985
uniprot id: I4CA69
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

706587:DESTI RS09325
gene id: 706587:DESTI_RS09325
uniprot id: I4C4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

706587:DESTI RS11250
gene id: 706587:DESTI_RS11250
uniprot id: I4C5U7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS12945
gene id: 706587:DESTI_RS12945
uniprot id: I4C6T7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

706587:DESTI RS12320
gene id: 706587:DESTI_RS12320
uniprot id: I4C6G0
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

706587:DESTI RS15065
gene id: 706587:DESTI_RS15065
uniprot id: I4C802
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

706587:DESTI RS23870
gene id: 706587:DESTI_RS23870
uniprot id: I4CCZ3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS13190
gene id: 706587:DESTI_RS13190
uniprot id: I4C6Z0
names: Similarity
messages: Belongs to the peptidase S58 family.

706587:DESTI RS15155
gene id: 706587:DESTI_RS15155
uniprot id: I4C819
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS23370
gene id: 706587:DESTI_RS23370
uniprot id: I4CCP5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

706587:DESTI RS13060
gene id: 706587:DESTI_RS13060
uniprot id: I4C6W2
names: Similarity
messages: Belongs to the LOG family.

706587:DESTI RS18445
gene id: 706587:DESTI_RS18445
uniprot id: I4C9W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

706587:DESTI RS00470
gene id: 706587:DESTI_RS00470
uniprot id: I4BZU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

706587:DESTI RS27655
gene id: 706587:DESTI_RS27655
uniprot id: I4CBT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

706587:DESTI RS13650
gene id: 706587:DESTI_RS13650
uniprot id: I4C780
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS05140
gene id: 706587:DESTI_RS05140
uniprot id: I4C2F6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS06895
gene id: 706587:DESTI_RS06895
uniprot id: I4C3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS16045
gene id: 706587:DESTI_RS16045
uniprot id: I4C8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

706587:DESTI RS20240
gene id: 706587:DESTI_RS20240
uniprot id: I4CAX5
names: Similarity
messages: Belongs to the leucine-binding protein family.

706587:DESTI RS11675
gene id: 706587:DESTI_RS11675
uniprot id: I4C633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

706587:DESTI RS15415
gene id: 706587:DESTI_RS15415
uniprot id: I4C868
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

706587:DESTI RS06280
gene id: 706587:DESTI_RS06280
uniprot id: I4C328
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

706587:DESTI RS21090
gene id: 706587:DESTI_RS21090
uniprot id: I4CBE8
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

706587:DESTI RS13440
gene id: 706587:DESTI_RS13440
uniprot id: I4C739
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

706587:DESTI RS27460
gene id: 706587:DESTI_RS27460
uniprot id: I4CEX0
names: Similarity
messages: Belongs to the SAICAR synthetase family.

706587:DESTI RS20940
gene id: 706587:DESTI_RS20940
uniprot id: I4CBB7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

706587:DESTI RS14420
gene id: 706587:DESTI_RS14420
uniprot id: I4C7M4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

706587:DESTI RS00425
gene id: 706587:DESTI_RS00425
uniprot id: I4BZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

706587:DESTI RS24145
gene id: 706587:DESTI_RS24145
uniprot id: I4CD45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

706587:DESTI RS01090
gene id: 706587:DESTI_RS01090
uniprot id: I4C072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

706587:DESTI RS06700
gene id: 706587:DESTI_RS06700
uniprot id: I4C3B3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

706587:DESTI RS21465
gene id: 706587:DESTI_RS21465
uniprot id: I4CBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS18485
gene id: 706587:DESTI_RS18485
uniprot id: I4C9X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

706587:DESTI RS13540
gene id: 706587:DESTI_RS13540
uniprot id: I4C759
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS10645
gene id: 706587:DESTI_RS10645
uniprot id: I4C5I1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS14065
gene id: 706587:DESTI_RS14065
uniprot id: I4C7F7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

706587:DESTI RS03595
gene id: 706587:DESTI_RS03595
uniprot id: I4C1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

706587:DESTI RS27905
gene id: 706587:DESTI_RS27905
uniprot id: I4CF57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

706587:DESTI RS27825
gene id: 706587:DESTI_RS27825
uniprot id: I4CF41
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

706587:DESTI RS15260
gene id: 706587:DESTI_RS15260
uniprot id: I4C839
names: Similarity
messages: Belongs to the peptidase S66 family.

706587:DESTI RS19030
gene id: 706587:DESTI_RS19030
uniprot id: I4CA78
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

706587:DESTI RS15535
gene id: 706587:DESTI_RS15535
uniprot id: I4C891
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS02025
gene id: 706587:DESTI_RS02025
uniprot id: I4C0P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS01040
gene id: 706587:DESTI_RS01040
uniprot id: I4C063
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS10775
gene id: 706587:DESTI_RS10775
uniprot id: I4C5K6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS13515
gene id: 706587:DESTI_RS13515
uniprot id: I4C754
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

706587:DESTI RS19300
gene id: 706587:DESTI_RS19300
uniprot id: I4CAD5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

706587:DESTI RS15180
gene id: 706587:DESTI_RS15180
uniprot id: I4C824
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS12930
gene id: 706587:DESTI_RS12930
uniprot id: I4C6T4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS08380
gene id: 706587:DESTI_RS08380
uniprot id: I4C497
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

706587:DESTI RS13755
gene id: 706587:DESTI_RS13755
uniprot id: I4C7A1
names: Similarity
messages: Belongs to the histone deacetylase family.

706587:DESTI RS26865
gene id: 706587:DESTI_RS26865
uniprot id: I4CEL6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS03110
gene id: 706587:DESTI_RS03110
uniprot id: I4C1B1
names: Similarity
messages: Belongs to the FGGY kinase family.

706587:DESTI RS18845
gene id: 706587:DESTI_RS18845
uniprot id: I4CA41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

706587:DESTI RS26715
gene id: 706587:DESTI_RS26715
uniprot id: I4CEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS19170
gene id: 706587:DESTI_RS19170
uniprot id: I4CAA8
names: Similarity
messages: Belongs to the HdrA family.

706587:DESTI RS00935
gene id: 706587:DESTI_RS00935
uniprot id: I4C042
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

706587:DESTI RS25055
gene id: 706587:DESTI_RS25055
uniprot id: I4CDM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

706587:DESTI RS26200
gene id: 706587:DESTI_RS26200
uniprot id: I4CE80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

706587:DESTI RS03630
gene id: 706587:DESTI_RS03630
uniprot id: I4C1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

706587:DESTI RS26050
gene id: 706587:DESTI_RS26050
uniprot id: I4CE49
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

706587:DESTI RS18280
gene id: 706587:DESTI_RS18280
uniprot id: I4C9S9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS14745
gene id: 706587:DESTI_RS14745
uniprot id: I4C7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

706587:DESTI RS07625
gene id: 706587:DESTI_RS07625
uniprot id: I4C3U6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

706587:DESTI RS19600
gene id: 706587:DESTI_RS19600
uniprot id: I4CAJ8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06040
gene id: 706587:DESTI_RS06040
uniprot id: I4C2X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

706587:DESTI RS29105
gene id: 706587:DESTI_RS29105
uniprot id: I4C9K6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

706587:DESTI RS20290
gene id: 706587:DESTI_RS20290
uniprot id: I4CAY5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

706587:DESTI RS11865
gene id: 706587:DESTI_RS11865
uniprot id: I4C667
names: Similarity
messages: Belongs to the GSP E family.

706587:DESTI RS23360
gene id: 706587:DESTI_RS23360
uniprot id: I4CCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

706587:DESTI RS27660
gene id: 706587:DESTI_RS27660
uniprot id: I4CBT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

706587:DESTI RS28880
gene id: 706587:DESTI_RS28880
uniprot id: I4C6Y9
names: Similarity
messages: Belongs to the barstar family.

706587:DESTI RS10360
gene id: 706587:DESTI_RS10360
uniprot id: I4C5D0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS24110
gene id: 706587:DESTI_RS24110
uniprot id: I4CD38
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

706587:DESTI RS22010
gene id: 706587:DESTI_RS22010
uniprot id: I4CBX8
names: Similarity
messages: Belongs to the Nth/MutY family.

706587:DESTI RS19480
gene id: 706587:DESTI_RS19480
uniprot id: I4CAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

706587:DESTI RS22120
gene id: 706587:DESTI_RS22120
uniprot id: I4CC03
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

706587:DESTI RS27535
gene id: 706587:DESTI_RS27535
uniprot id: I4CEY6
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18900
gene id: 706587:DESTI_RS18900
uniprot id: I4CA52
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS14875
gene id: 706587:DESTI_RS14875
uniprot id: I4C7W5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

706587:DESTI RS28255
gene id: 706587:DESTI_RS28255
uniprot id: I4C0E0
names: Subcellular Location Annotation
messages: Cell inner membrane

706587:DESTI RS24445
gene id: 706587:DESTI_RS24445
uniprot id: I4CDA2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS08100
gene id: 706587:DESTI_RS08100
uniprot id: I4C439
names: Similarity
messages: Belongs to the peptidase S16 family.

706587:DESTI RS02575
gene id: 706587:DESTI_RS02575
uniprot id: I4C107
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

706587:DESTI RS04030
gene id: 706587:DESTI_RS04030
uniprot id: I4C1U5
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

706587:DESTI RS06285
gene id: 706587:DESTI_RS06285
uniprot id: I4C329
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

706587:DESTI RS05870
gene id: 706587:DESTI_RS05870
uniprot id: I4C2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

706587:DESTI RS24135
gene id: 706587:DESTI_RS24135
uniprot id: I4CD43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

706587:DESTI RS17350
gene id: 706587:DESTI_RS17350
uniprot id: I4C9A0
names: Similarity
messages: Belongs to the UPF0597 family.

706587:DESTI RS09740
gene id: 706587:DESTI_RS09740
uniprot id: I4C512
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

706587:DESTI RS03610
gene id: 706587:DESTI_RS03610
uniprot id: I4C1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

706587:DESTI RS26270
gene id: 706587:DESTI_RS26270
uniprot id: I4CE95
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS16430
gene id: 706587:DESTI_RS16430
uniprot id: I4C8R8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

706587:DESTI RS26155
gene id: 706587:DESTI_RS26155
uniprot id: I4CE71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

706587:DESTI RS03715
gene id: 706587:DESTI_RS03715
uniprot id: I4C1N2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

706587:DESTI RS18760
gene id: 706587:DESTI_RS18760
uniprot id: I4CA27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

706587:DESTI RS02715
gene id: 706587:DESTI_RS02715
uniprot id: I4C139
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

706587:DESTI RS20595
gene id: 706587:DESTI_RS20595
uniprot id: I4CB49
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

706587:DESTI RS08475
gene id: 706587:DESTI_RS08475
uniprot id: I4C4B5
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

706587:DESTI RS22855
gene id: 706587:DESTI_RS22855
uniprot id: I4CCE9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS11775
gene id: 706587:DESTI_RS11775
uniprot id: I4C649
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

706587:DESTI RS05670
gene id: 706587:DESTI_RS05670
uniprot id: I4C2Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

706587:DESTI RS27915
gene id: 706587:DESTI_RS27915
uniprot id: I4CF60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

706587:DESTI RS28510
gene id: 706587:DESTI_RS28510
uniprot id: I4C326
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

706587:DESTI RS28450
gene id: 706587:DESTI_RS28450
uniprot id: I4C272
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

706587:DESTI RS15600
gene id: 706587:DESTI_RS15600
uniprot id: I4C8A3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

706587:DESTI RS18615
gene id: 706587:DESTI_RS18615
uniprot id: I4C9Z8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

706587:DESTI RS15400
gene id: 706587:DESTI_RS15400
uniprot id: I4C865
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

706587:DESTI RS27085
gene id: 706587:DESTI_RS27085
uniprot id: I4CEQ4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

706587:DESTI RS22255
gene id: 706587:DESTI_RS22255
uniprot id: I4CC28
names: Similarity
messages: Belongs to the LarC family.

706587:DESTI RS18435
gene id: 706587:DESTI_RS18435
uniprot id: I4C9W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

706587:DESTI RS18210
gene id: 706587:DESTI_RS18210
uniprot id: I4C9R5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS05700
gene id: 706587:DESTI_RS05700
uniprot id: I4C2R5
names: Subcellular Location Annotation
messages: Cytoplasm

706587:DESTI RS21285
gene id: 706587:DESTI_RS21285
uniprot id: I4CBI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

706587:DESTI RS12070
gene id: 706587:DESTI_RS12070
uniprot id: I4C6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

706587:DESTI RS18970
gene id: 706587:DESTI_RS18970
uniprot id: I4CA66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

706587:DESTI RS14340
gene id: 706587:DESTI_RS14340
uniprot id: I4C7L2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

706587:DESTI RS14060
gene id: 706587:DESTI_RS14060
uniprot id: I4C7F6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

706587:DESTI RS18055
gene id: 706587:DESTI_RS18055
uniprot id: I4C9N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

706587:DESTI RS16655
gene id: 706587:DESTI_RS16655
uniprot id: I4C8W2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

706587:DESTI RS20540
gene id: 706587:DESTI_RS20540
uniprot id: I4CB37
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

706587:DESTI RS05330
gene id: 706587:DESTI_RS05330
uniprot id: I4C2J6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

706587:DESTI RS08190
gene id: 706587:DESTI_RS08190
uniprot id: I4C458
names: Subcellular Location Annotation
messages: Peroxisome

706587:DESTI RS09510
gene id: 706587:DESTI_RS09510
uniprot id: I4C4W8
names: Similarity
messages: Belongs to the UxaA family.

706587:DESTI RS27215
gene id: 706587:DESTI_RS27215
uniprot id: I4CES7
names: Similarity
messages: Belongs to the P(II) protein family.

706587:DESTI RS14215
gene id: 706587:DESTI_RS14215
uniprot id: I4C7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

706587:DESTI RS24355
gene id: 706587:DESTI_RS24355
uniprot id: I4CD85
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

706587:DESTI RS14560
gene id: 706587:DESTI_RS14560
uniprot id: I4C7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

706587:DESTI RS06260
gene id: 706587:DESTI_RS06260
uniprot id: I4C323
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

706587:DESTI RS27380
gene id: 706587:DESTI_RS27380
uniprot id: I4CEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS19190
gene id: 706587:DESTI_RS19190
uniprot id: I4CAB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

706587:DESTI RS21160
gene id: 706587:DESTI_RS21160
uniprot id: I4CBF7
names: Similarity
messages: Belongs to the HdrA family.

706587:DESTI RS03390
gene id: 706587:DESTI_RS03390
uniprot id: I4C1G9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS19850
gene id: 706587:DESTI_RS19850
uniprot id: I4CAP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS23320
gene id: 706587:DESTI_RS23320
uniprot id: I4CCN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS05310
gene id: 706587:DESTI_RS05310
uniprot id: I4C2J3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

706587:DESTI RS05180
gene id: 706587:DESTI_RS05180
uniprot id: I4C2G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS06355
gene id: 706587:DESTI_RS06355
uniprot id: I4C343
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

706587:DESTI RS19130
gene id: 706587:DESTI_RS19130
uniprot id: I4CA99
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

706587:DESTI RS03155
gene id: 706587:DESTI_RS03155
uniprot id: I4C1C1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

706587:DESTI RS14335
gene id: 706587:DESTI_RS14335
uniprot id: I4C7L1
names: Similarity
messages: Belongs to the acylphosphatase family.

706587:DESTI RS13720
gene id: 706587:DESTI_RS13720
uniprot id: I4C794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

706587:DESTI RS20410
gene id: 706587:DESTI_RS20410
uniprot id: I4CB11
names: Similarity
messages: Belongs to the TrpC family.

706587:DESTI RS05605
gene id: 706587:DESTI_RS05605
uniprot id: I4C2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

706587:DESTI RS18765
gene id: 706587:DESTI_RS18765
uniprot id: I4CA28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

706587:DESTI RS28655
gene id: 706587:DESTI_RS28655
uniprot id: I4C4W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS26025
gene id: 706587:DESTI_RS26025
uniprot id: I4CE45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

706587:DESTI RS01920
gene id: 706587:DESTI_RS01920
uniprot id: I4C0M9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

706587:DESTI RS24015
gene id: 706587:DESTI_RS24015
uniprot id: I4CD20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

706587:DESTI RS09470
gene id: 706587:DESTI_RS09470
uniprot id: I4C4V9
names: Similarity
messages: Belongs to the class-I fumarase family.

706587:DESTI RS19060
gene id: 706587:DESTI_RS19060
uniprot id: I4CA85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

706587:DESTI RS19115
gene id: 706587:DESTI_RS19115
uniprot id: I4CA96
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

706587:DESTI RS21355
gene id: 706587:DESTI_RS21355
uniprot id: I4CBJ7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00840
gene id: 706587:DESTI_RS00840
uniprot id: I4C022
names: Similarity
messages: Belongs to the AOR/FOR family.

706587:DESTI RS28260
gene id: 706587:DESTI_RS28260
uniprot id: I4C0E5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

706587:DESTI RS03590
gene id: 706587:DESTI_RS03590
uniprot id: I4C1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

706587:DESTI RS02300
gene id: 706587:DESTI_RS02300
uniprot id: I4C0V5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS04865
gene id: 706587:DESTI_RS04865
uniprot id: I4C2A0
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

706587:DESTI RS08585
gene id: 706587:DESTI_RS08585
uniprot id: I4C4D7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

706587:DESTI RS08035
gene id: 706587:DESTI_RS08035
uniprot id: I4C425
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

706587:DESTI RS02540
gene id: 706587:DESTI_RS02540
uniprot id: I4C0Z9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

706587:DESTI RS24345
gene id: 706587:DESTI_RS24345
uniprot id: I4CD84
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

706587:DESTI RS00250
gene id: 706587:DESTI_RS00250
uniprot id: I4BZQ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

706587:DESTI RS13005
gene id: 706587:DESTI_RS13005
uniprot id: I4C6V2
names: Similarity
messages: Belongs to the citrate synthase family.

706587:DESTI RS07590
gene id: 706587:DESTI_RS07590
uniprot id: I4C3U0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS09070
gene id: 706587:DESTI_RS09070
uniprot id: I4C4M9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS23815
gene id: 706587:DESTI_RS23815
uniprot id: I4CCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

706587:DESTI RS26955
gene id: 706587:DESTI_RS26955
uniprot id: I4CEN4
names: Similarity
messages: Belongs to the MtrH family.

706587:DESTI RS19785
gene id: 706587:DESTI_RS19785
uniprot id: I4CAN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

706587:DESTI RS20485
gene id: 706587:DESTI_RS20485
uniprot id: I4CB25
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

706587:DESTI RS19550
gene id: 706587:DESTI_RS19550
uniprot id: I4CAI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

706587:DESTI RS13690
gene id: 706587:DESTI_RS13690
uniprot id: I4C788
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

706587:DESTI RS20165
gene id: 706587:DESTI_RS20165
uniprot id: I4CAW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

706587:DESTI RS06845
gene id: 706587:DESTI_RS06845
uniprot id: I4C3E3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS16450
gene id: 706587:DESTI_RS16450
uniprot id: I4C8S1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

706587:DESTI RS05665
gene id: 706587:DESTI_RS05665
uniprot id: I4C2Q8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

706587:DESTI RS26085
gene id: 706587:DESTI_RS26085
uniprot id: I4CE57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

706587:DESTI RS01725
gene id: 706587:DESTI_RS01725
uniprot id: I4C0I9
names: Subcellular Location Annotation
messages: Periplasm

706587:DESTI RS06080
gene id: 706587:DESTI_RS06080
uniprot id: I4C2Y6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS20380
gene id: 706587:DESTI_RS20380
uniprot id: I4CB05
names: Similarity
messages: Belongs to the HupF/HypC family.

706587:DESTI RS16965
gene id: 706587:DESTI_RS16965
uniprot id: I4C927
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

706587:DESTI RS20745
gene id: 706587:DESTI_RS20745
uniprot id: I4CB78
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS10020
gene id: 706587:DESTI_RS10020
uniprot id: I4C565
names: Similarity
messages: Belongs to the leucine-binding protein family.

706587:DESTI RS18800
gene id: 706587:DESTI_RS18800
uniprot id: I4CA33
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

706587:DESTI RS07875
gene id: 706587:DESTI_RS07875
uniprot id: I4C3Z4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

706587:DESTI RS22135
gene id: 706587:DESTI_RS22135
uniprot id: I4CC05
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

706587:DESTI RS10590
gene id: 706587:DESTI_RS10590
uniprot id: I4C5H1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS11805
gene id: 706587:DESTI_RS11805
uniprot id: I4C655
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

706587:DESTI RS21290
gene id: 706587:DESTI_RS21290
uniprot id: I4CBI4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS21645
gene id: 706587:DESTI_RS21645
uniprot id: I4CBQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

706587:DESTI RS12350
gene id: 706587:DESTI_RS12350
uniprot id: I4C6G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

706587:DESTI RS14190
gene id: 706587:DESTI_RS14190
uniprot id: I4C7I2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

706587:DESTI RS24575
gene id: 706587:DESTI_RS24575
uniprot id: I4CDC6
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

706587:DESTI RS06320
gene id: 706587:DESTI_RS06320
uniprot id: I4C336
names: Similarity
messages: Belongs to the UDPGP type 1 family.

706587:DESTI RS09425
gene id: 706587:DESTI_RS09425
uniprot id: I4C4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS08470
gene id: 706587:DESTI_RS08470
uniprot id: I4C4B4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

706587:DESTI RS23285
gene id: 706587:DESTI_RS23285
uniprot id: I4CCM9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

706587:DESTI RS24705
gene id: 706587:DESTI_RS24705
uniprot id: I4CDF2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

706587:DESTI RS20480
gene id: 706587:DESTI_RS20480
uniprot id: I4CB24
names: Subcellular Location Annotation
messages: Cytoplasm

706587:DESTI RS01655
gene id: 706587:DESTI_RS01655
uniprot id: I4C0H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS23015
gene id: 706587:DESTI_RS23015
uniprot id: I4CCH8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

706587:DESTI RS08180
gene id: 706587:DESTI_RS08180
uniprot id: I4C456
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS10310
gene id: 706587:DESTI_RS10310
uniprot id: I4C5C1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS26045
gene id: 706587:DESTI_RS26045
uniprot id: I4CE48
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

706587:DESTI RS28540
gene id: 706587:DESTI_RS28540
uniprot id: I4C3H8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

706587:DESTI RS09850
gene id: 706587:DESTI_RS09850
uniprot id: I4C532
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

706587:DESTI RS15495
gene id: 706587:DESTI_RS15495
uniprot id: I4C883
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

706587:DESTI RS22620
gene id: 706587:DESTI_RS22620
uniprot id: I4CCA3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS09765
gene id: 706587:DESTI_RS09765
uniprot id: I4C517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

706587:DESTI RS01045
gene id: 706587:DESTI_RS01045
uniprot id: I4C064
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

706587:DESTI RS08860
gene id: 706587:DESTI_RS08860
uniprot id: I4C4I9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06815
gene id: 706587:DESTI_RS06815
uniprot id: I4C3D6
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS19905
gene id: 706587:DESTI_RS19905
uniprot id: I4CAQ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

706587:DESTI RS28535
gene id: 706587:DESTI_RS28535
uniprot id: I4C3H5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18880
gene id: 706587:DESTI_RS18880
uniprot id: I4CA48
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS17925
gene id: 706587:DESTI_RS17925
uniprot id: I4C9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS23180
gene id: 706587:DESTI_RS23180
uniprot id: I4CCK9
names: Similarity
messages: Belongs to the GARS family.

706587:DESTI RS27570
gene id: 706587:DESTI_RS27570
uniprot id: I4CEZ4
names: Similarity
messages: Belongs to the Lgt family.

706587:DESTI RS27810
gene id: 706587:DESTI_RS27810
uniprot id: I4CF38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

706587:DESTI RS15925
gene id: 706587:DESTI_RS15925
uniprot id: I4C8G5
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

706587:DESTI RS21400
gene id: 706587:DESTI_RS21400
uniprot id: I4CBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS05750
gene id: 706587:DESTI_RS05750
uniprot id: I4C2S4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS25990
gene id: 706587:DESTI_RS25990
uniprot id: I4CE42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

706587:DESTI RS24680
gene id: 706587:DESTI_RS24680
uniprot id: I4CDE6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS26140
gene id: 706587:DESTI_RS26140
uniprot id: I4CE68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

706587:DESTI RS05565
gene id: 706587:DESTI_RS05565
uniprot id: I4C2N9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

706587:DESTI RS08335
gene id: 706587:DESTI_RS08335
uniprot id: I4C488
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

706587:DESTI RS08440
gene id: 706587:DESTI_RS08440
uniprot id: I4C4A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

706587:DESTI RS07945
gene id: 706587:DESTI_RS07945
uniprot id: I4C408
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

706587:DESTI RS02570
gene id: 706587:DESTI_RS02570
uniprot id: I4C106
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

706587:DESTI RS02545
gene id: 706587:DESTI_RS02545
uniprot id: I4C100
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

706587:DESTI RS22470
gene id: 706587:DESTI_RS22470
uniprot id: I4CC70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS07900
gene id: 706587:DESTI_RS07900
uniprot id: I4C3Z9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS15555
gene id: 706587:DESTI_RS15555
uniprot id: I4C895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

706587:DESTI RS05165
gene id: 706587:DESTI_RS05165
uniprot id: I4C2G2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

706587:DESTI RS14635
gene id: 706587:DESTI_RS14635
uniprot id: I4C7S0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

706587:DESTI RS29250
gene id: 706587:DESTI_RS29250
uniprot id: I4CBJ9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

706587:DESTI RS05615
gene id: 706587:DESTI_RS05615
uniprot id: I4C2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

706587:DESTI RS23600
gene id: 706587:DESTI_RS23600
uniprot id: I4CCU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS13940
gene id: 706587:DESTI_RS13940
uniprot id: I4C7D2
names: Similarity
messages: Belongs to the AAA ATPase family.

706587:DESTI RS07385
gene id: 706587:DESTI_RS07385
uniprot id: I4C3P8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS17765
gene id: 706587:DESTI_RS17765
uniprot id: I4C9I0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

706587:DESTI RS20920
gene id: 706587:DESTI_RS20920
uniprot id: I4CBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

706587:DESTI RS04195
gene id: 706587:DESTI_RS04195
uniprot id: I4C1X6
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS12670
gene id: 706587:DESTI_RS12670
uniprot id: I4C6M8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS03675
gene id: 706587:DESTI_RS03675
uniprot id: I4C1M4
names: Similarity
messages: Belongs to the CapA family.

706587:DESTI RS24235
gene id: 706587:DESTI_RS24235
uniprot id: I4CD62
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

706587:DESTI RS01475
gene id: 706587:DESTI_RS01475
uniprot id: I4C0E2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS24970
gene id: 706587:DESTI_RS24970
uniprot id: I4CDK4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS26820
gene id: 706587:DESTI_RS26820
uniprot id: I4CEK7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

706587:DESTI RS06920
gene id: 706587:DESTI_RS06920
uniprot id: I4C3F8
names: Subunit
messages: Heterodimer of a large and a small subunit.

706587:DESTI RS16150
gene id: 706587:DESTI_RS16150
uniprot id: I4C8K9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS18480
gene id: 706587:DESTI_RS18480
uniprot id: I4C9X0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

706587:DESTI RS00900
gene id: 706587:DESTI_RS00900
uniprot id: I4C034
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

706587:DESTI RS19310
gene id: 706587:DESTI_RS19310
uniprot id: I4CAD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

706587:DESTI RS01850
gene id: 706587:DESTI_RS01850
uniprot id: I4C0L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

706587:DESTI RS24690
gene id: 706587:DESTI_RS24690
uniprot id: I4CDE8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05695
gene id: 706587:DESTI_RS05695
uniprot id: I4C2R4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS01740
gene id: 706587:DESTI_RS01740
uniprot id: I4C0J2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

706587:DESTI RS11310
gene id: 706587:DESTI_RS11310
uniprot id: I4C5W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS21280
gene id: 706587:DESTI_RS21280
uniprot id: I4CBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

706587:DESTI RS21750
gene id: 706587:DESTI_RS21750
uniprot id: I4CBS5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

706587:DESTI RS14915
gene id: 706587:DESTI_RS14915
uniprot id: I4C7X3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

706587:DESTI RS19000
gene id: 706587:DESTI_RS19000
uniprot id: I4CA72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

706587:DESTI RS12375
gene id: 706587:DESTI_RS12375
uniprot id: I4C6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

706587:DESTI RS13705
gene id: 706587:DESTI_RS13705
uniprot id: I4C791
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS08445
gene id: 706587:DESTI_RS08445
uniprot id: I4C4A9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

706587:DESTI RS02135
gene id: 706587:DESTI_RS02135
uniprot id: I4C0S0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

706587:DESTI RS02360
gene id: 706587:DESTI_RS02360
uniprot id: I4C0W7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

706587:DESTI RS24490
gene id: 706587:DESTI_RS24490
uniprot id: I4CDA9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

706587:DESTI RS17460
gene id: 706587:DESTI_RS17460
uniprot id: I4C9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

706587:DESTI RS00480
gene id: 706587:DESTI_RS00480
uniprot id: I4BZV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

706587:DESTI RS15770
gene id: 706587:DESTI_RS15770
uniprot id: I4C8D7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS23210
gene id: 706587:DESTI_RS23210
uniprot id: I4CCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

706587:DESTI RS21810
gene id: 706587:DESTI_RS21810
uniprot id: I4CBT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

706587:DESTI RS15235
gene id: 706587:DESTI_RS15235
uniprot id: I4C834
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

706587:DESTI RS14395
gene id: 706587:DESTI_RS14395
uniprot id: I4C7L9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS23310
gene id: 706587:DESTI_RS23310
uniprot id: I4CCN3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS16260
gene id: 706587:DESTI_RS16260
uniprot id: I4C8N1
names: Similarity
messages: Belongs to the UxaA family.

706587:DESTI RS18715
gene id: 706587:DESTI_RS18715
uniprot id: I4CA18
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS31620
gene id: 706587:DESTI_RS31620
uniprot id: I4C9S6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

706587:DESTI RS11135
gene id: 706587:DESTI_RS11135
uniprot id: I4C5S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS02225
gene id: 706587:DESTI_RS02225
uniprot id: I4C0T9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS19120
gene id: 706587:DESTI_RS19120
uniprot id: I4CA97
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

706587:DESTI RS25305
gene id: 706587:DESTI_RS25305
uniprot id: I4CDR9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS10015
gene id: 706587:DESTI_RS10015
uniprot id: I4C564
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05435
gene id: 706587:DESTI_RS05435
uniprot id: I4C2L2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

706587:DESTI RS13660
gene id: 706587:DESTI_RS13660
uniprot id: I4C782
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS16090
gene id: 706587:DESTI_RS16090
uniprot id: I4C8J8
names: Similarity
messages: Belongs to the TPP enzyme family.

706587:DESTI RS23315
gene id: 706587:DESTI_RS23315
uniprot id: I4CCN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

706587:DESTI RS15145
gene id: 706587:DESTI_RS15145
uniprot id: I4C817
names: Similarity
messages: Belongs to the leucine-binding protein family.

706587:DESTI RS22615
gene id: 706587:DESTI_RS22615
uniprot id: I4CCA2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS16305
gene id: 706587:DESTI_RS16305
uniprot id: I4C8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

706587:DESTI RS10525
gene id: 706587:DESTI_RS10525
uniprot id: I4C5F9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS21230
gene id: 706587:DESTI_RS21230
uniprot id: I4CBH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

706587:DESTI RS26870
gene id: 706587:DESTI_RS26870
uniprot id: I4CEL7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS09595
gene id: 706587:DESTI_RS09595
uniprot id: I4C4Y4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

706587:DESTI RS20295
gene id: 706587:DESTI_RS20295
uniprot id: I4CAY6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

706587:DESTI RS19780
gene id: 706587:DESTI_RS19780
uniprot id: I4CAN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

706587:DESTI RS23895
gene id: 706587:DESTI_RS23895
uniprot id: I4CCZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS05295
gene id: 706587:DESTI_RS05295
uniprot id: I4C2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

706587:DESTI RS08465
gene id: 706587:DESTI_RS08465
uniprot id: I4C4B3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

706587:DESTI RS10335
gene id: 706587:DESTI_RS10335
uniprot id: I4C5C5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

706587:DESTI RS00040
gene id: 706587:DESTI_RS00040
uniprot id: I4BZL6
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20980
gene id: 706587:DESTI_RS20980
uniprot id: I4CBC5
names: Similarity
messages: Belongs to the leucine-binding protein family.

706587:DESTI RS14485
gene id: 706587:DESTI_RS14485
uniprot id: I4C7N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

706587:DESTI RS23525
gene id: 706587:DESTI_RS23525
uniprot id: I4CCS6
names: Similarity
messages: Belongs to the DprA/Smf family.

706587:DESTI RS10125
gene id: 706587:DESTI_RS10125
uniprot id: I4C585
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS29285
gene id: 706587:DESTI_RS29285
uniprot id: I4CC11
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

706587:DESTI RS03385
gene id: 706587:DESTI_RS03385
uniprot id: I4C1G8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05945
gene id: 706587:DESTI_RS05945
uniprot id: I4C2W4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

706587:DESTI RS18430
gene id: 706587:DESTI_RS18430
uniprot id: I4C9V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

706587:DESTI RS18240
gene id: 706587:DESTI_RS18240
uniprot id: I4C9S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS23400
gene id: 706587:DESTI_RS23400
uniprot id: I4CCQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

706587:DESTI RS09440
gene id: 706587:DESTI_RS09440
uniprot id: I4C4V3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05455
gene id: 706587:DESTI_RS05455
uniprot id: I4C2L6
names: Similarity
messages: Belongs to the bacterial secretin family.

706587:DESTI RS12410
gene id: 706587:DESTI_RS12410
uniprot id: I4C6H6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS09475
gene id: 706587:DESTI_RS09475
uniprot id: I4C4W0
names: Similarity
messages: Belongs to the class-I fumarase family.

706587:DESTI RS27235
gene id: 706587:DESTI_RS27235
uniprot id: I4CET1
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

706587:DESTI RS04760
gene id: 706587:DESTI_RS04760
uniprot id: I4C280
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

706587:DESTI RS02285
gene id: 706587:DESTI_RS02285
uniprot id: I4C0V2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06085
gene id: 706587:DESTI_RS06085
uniprot id: I4C2Y7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

706587:DESTI RS09350
gene id: 706587:DESTI_RS09350
uniprot id: I4C4T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

706587:DESTI RS27530
gene id: 706587:DESTI_RS27530
uniprot id: I4CEY5
names: Similarity
messages: Belongs to the leucine-binding protein family.

706587:DESTI RS09630
gene id: 706587:DESTI_RS09630
uniprot id: I4C4Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

706587:DESTI RS08310
gene id: 706587:DESTI_RS08310
uniprot id: I4C483
names: Similarity
messages: Belongs to the thioredoxin family.

706587:DESTI RS20360
gene id: 706587:DESTI_RS20360
uniprot id: I4CB01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS28445
gene id: 706587:DESTI_RS28445
uniprot id: I4C259
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

706587:DESTI RS16975
gene id: 706587:DESTI_RS16975
uniprot id: I4C929
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

706587:DESTI RS12630
gene id: 706587:DESTI_RS12630
uniprot id: I4C6M0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS03350
gene id: 706587:DESTI_RS03350
uniprot id: I4C1G0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS00255
gene id: 706587:DESTI_RS00255
uniprot id: I4BZQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

706587:DESTI RS15350
gene id: 706587:DESTI_RS15350
uniprot id: I4C855
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

706587:DESTI RS20990
gene id: 706587:DESTI_RS20990
uniprot id: I4CBC7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS01205
gene id: 706587:DESTI_RS01205
uniprot id: I4C095
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

706587:DESTI RS19210
gene id: 706587:DESTI_RS19210
uniprot id: I4CAB6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS26215
gene id: 706587:DESTI_RS26215
uniprot id: I4CE84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

706587:DESTI RS23355
gene id: 706587:DESTI_RS23355
uniprot id: I4CCP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

706587:DESTI RS12870
gene id: 706587:DESTI_RS12870
uniprot id: I4C6S2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

706587:DESTI RS00280
gene id: 706587:DESTI_RS00280
uniprot id: I4BZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

706587:DESTI RS02175
gene id: 706587:DESTI_RS02175
uniprot id: I4C0S8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS14390
gene id: 706587:DESTI_RS14390
uniprot id: I4C7L8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26150
gene id: 706587:DESTI_RS26150
uniprot id: I4CE70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

706587:DESTI RS24630
gene id: 706587:DESTI_RS24630
uniprot id: I4CDD8
names: Similarity
messages: Belongs to the UPF0751 family.

706587:DESTI RS12650
gene id: 706587:DESTI_RS12650
uniprot id: I4C6M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

706587:DESTI RS26110
gene id: 706587:DESTI_RS26110
uniprot id: I4CE62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

706587:DESTI RS04070
gene id: 706587:DESTI_RS04070
uniprot id: I4C1V2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS19915
gene id: 706587:DESTI_RS19915
uniprot id: I4CAR2
names: Similarity
messages: Belongs to the ribF family.

706587:DESTI RS01735
gene id: 706587:DESTI_RS01735
uniprot id: I4C0J1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

706587:DESTI RS18215
gene id: 706587:DESTI_RS18215
uniprot id: I4C9R6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

706587:DESTI RS12280
gene id: 706587:DESTI_RS12280
uniprot id: I4C6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

706587:DESTI RS19830
gene id: 706587:DESTI_RS19830
uniprot id: I4CAP5
names: Similarity
messages: Belongs to the TlyA family.

706587:DESTI RS25490
gene id: 706587:DESTI_RS25490
uniprot id: I4CDV0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS02220
gene id: 706587:DESTI_RS02220
uniprot id: I4C0T8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS05255
gene id: 706587:DESTI_RS05255
uniprot id: I4C2I2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

706587:DESTI RS15705
gene id: 706587:DESTI_RS15705
uniprot id: I4C8C4
names: Similarity
messages: Belongs to the peptidase A31 family.

706587:DESTI RS14500
gene id: 706587:DESTI_RS14500
uniprot id: I4C7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

706587:DESTI RS04860
gene id: 706587:DESTI_RS04860
uniprot id: I4C299
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS08320
gene id: 706587:DESTI_RS08320
uniprot id: I4C485
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

706587:DESTI RS11160
gene id: 706587:DESTI_RS11160
uniprot id: I4C5S8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS05990
gene id: 706587:DESTI_RS05990
uniprot id: I4C2X1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

706587:DESTI RS20050
gene id: 706587:DESTI_RS20050
uniprot id: I4CAT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

706587:DESTI RS20500
gene id: 706587:DESTI_RS20500
uniprot id: I4CB28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

706587:DESTI RS02620
gene id: 706587:DESTI_RS02620
uniprot id: I4C117
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00890
gene id: 706587:DESTI_RS00890
uniprot id: I4C032
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

706587:DESTI RS20935
gene id: 706587:DESTI_RS20935
uniprot id: I4CBB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS00025
gene id: 706587:DESTI_RS00025
uniprot id: I4BZL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

706587:DESTI RS26070
gene id: 706587:DESTI_RS26070
uniprot id: I4CE53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

706587:DESTI RS19890
gene id: 706587:DESTI_RS19890
uniprot id: I4CAQ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS27815
gene id: 706587:DESTI_RS27815
uniprot id: I4CF39
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

706587:DESTI RS20230
gene id: 706587:DESTI_RS20230
uniprot id: I4CAX3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS22115
gene id: 706587:DESTI_RS22115
uniprot id: I4CC02
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS03980
gene id: 706587:DESTI_RS03980
uniprot id: I4C1T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

706587:DESTI RS27490
gene id: 706587:DESTI_RS27490
uniprot id: I4CEX6
names: Similarity
messages: Belongs to the sigma-54 factor family.

706587:DESTI RS07525
gene id: 706587:DESTI_RS07525
uniprot id: I4C3S6
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS04730
gene id: 706587:DESTI_RS04730
uniprot id: I4C273
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS29510
gene id: 706587:DESTI_RS29510
uniprot id: I4CE44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

706587:DESTI RS09460
gene id: 706587:DESTI_RS09460
uniprot id: I4C4V7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

706587:DESTI RS04590
gene id: 706587:DESTI_RS04590
uniprot id: I4C244
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS02260
gene id: 706587:DESTI_RS02260
uniprot id: I4C0U7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

706587:DESTI RS31640
gene id: 706587:DESTI_RS31640
uniprot id: I4CC46
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS18910
gene id: 706587:DESTI_RS18910
uniprot id: I4CA54
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

706587:DESTI RS17640
gene id: 706587:DESTI_RS17640
uniprot id: I4C9F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

706587:DESTI RS05300
gene id: 706587:DESTI_RS05300
uniprot id: I4C2J1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

706587:DESTI RS18375
gene id: 706587:DESTI_RS18375
uniprot id: I4C9U9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS12235
gene id: 706587:DESTI_RS12235
uniprot id: I4C6E3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS28440
gene id: 706587:DESTI_RS28440
uniprot id: I4C258
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

706587:DESTI RS01120
gene id: 706587:DESTI_RS01120
uniprot id: I4C078
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

706587:DESTI RS24245
gene id: 706587:DESTI_RS24245
uniprot id: I4CD64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

706587:DESTI RS07975
gene id: 706587:DESTI_RS07975
uniprot id: I4C414
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

706587:DESTI RS06250
gene id: 706587:DESTI_RS06250
uniprot id: I4C321
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20555
gene id: 706587:DESTI_RS20555
uniprot id: I4CB40
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

706587:DESTI RS26495
gene id: 706587:DESTI_RS26495
uniprot id: I4CEE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

706587:DESTI RS09625
gene id: 706587:DESTI_RS09625
uniprot id: I4C4Z0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

706587:DESTI RS12735
gene id: 706587:DESTI_RS12735
uniprot id: I4C6P4
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

706587:DESTI RS05925
gene id: 706587:DESTI_RS05925
uniprot id: I4C2W0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS08375
gene id: 706587:DESTI_RS08375
uniprot id: I4C496
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

706587:DESTI RS15575
gene id: 706587:DESTI_RS15575
uniprot id: I4C899
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

706587:DESTI RS14450
gene id: 706587:DESTI_RS14450
uniprot id: I4C7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

706587:DESTI RS06710
gene id: 706587:DESTI_RS06710
uniprot id: I4C3B5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

706587:DESTI RS16360
gene id: 706587:DESTI_RS16360
uniprot id: I4C8Q2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS06230
gene id: 706587:DESTI_RS06230
uniprot id: I4C317
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

706587:DESTI RS18440
gene id: 706587:DESTI_RS18440
uniprot id: I4C9W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

706587:DESTI RS19125
gene id: 706587:DESTI_RS19125
uniprot id: I4CA98
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

706587:DESTI RS04120
gene id: 706587:DESTI_RS04120
uniprot id: I4C1W1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS27220
gene id: 706587:DESTI_RS27220
uniprot id: I4CES8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

706587:DESTI RS16660
gene id: 706587:DESTI_RS16660
uniprot id: I4C8W3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS12305
gene id: 706587:DESTI_RS12305
uniprot id: I4C6F7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

706587:DESTI RS24980
gene id: 706587:DESTI_RS24980
uniprot id: I4CDK6
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26210
gene id: 706587:DESTI_RS26210
uniprot id: I4CE82
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

706587:DESTI RS18150
gene id: 706587:DESTI_RS18150
uniprot id: I4C9Q4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS11870
gene id: 706587:DESTI_RS11870
uniprot id: I4C668
names: Similarity
messages: Belongs to the GSP E family.

706587:DESTI RS19390
gene id: 706587:DESTI_RS19390
uniprot id: I4CAF3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26030
gene id: 706587:DESTI_RS26030
uniprot id: I4CE46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

706587:DESTI RS05640
gene id: 706587:DESTI_RS05640
uniprot id: I4C2Q3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

706587:DESTI RS03345
gene id: 706587:DESTI_RS03345
uniprot id: I4C1F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

706587:DESTI RS13170
gene id: 706587:DESTI_RS13170
uniprot id: I4C6Y6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS03455
gene id: 706587:DESTI_RS03455
uniprot id: I4C1I1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00215
gene id: 706587:DESTI_RS00215
uniprot id: I4BZQ0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

706587:DESTI RS15410
gene id: 706587:DESTI_RS15410
uniprot id: I4C867
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

706587:DESTI RS26170
gene id: 706587:DESTI_RS26170
uniprot id: I4CE74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

706587:DESTI RS13075
gene id: 706587:DESTI_RS13075
uniprot id: I4C6W5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS12760
gene id: 706587:DESTI_RS12760
uniprot id: I4C6P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

706587:DESTI RS04750
gene id: 706587:DESTI_RS04750
uniprot id: I4C277
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20280
gene id: 706587:DESTI_RS20280
uniprot id: I4CAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

706587:DESTI RS06635
gene id: 706587:DESTI_RS06635
uniprot id: I4C399
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

706587:DESTI RS03575
gene id: 706587:DESTI_RS03575
uniprot id: I4C1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

706587:DESTI RS11905
gene id: 706587:DESTI_RS11905
uniprot id: I4C675
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

706587:DESTI RS12205
gene id: 706587:DESTI_RS12205
uniprot id: I4C6D6
names: Similarity
messages: Belongs to the UPF0047 family.

706587:DESTI RS07050
gene id: 706587:DESTI_RS07050
uniprot id: I4C3I5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

706587:DESTI RS09480
gene id: 706587:DESTI_RS09480
uniprot id: I4C4W1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS26475
gene id: 706587:DESTI_RS26475
uniprot id: I4CED9
names: Similarity
messages: Belongs to the leucine-binding protein family.

706587:DESTI RS26055
gene id: 706587:DESTI_RS26055
uniprot id: I4CE50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

706587:DESTI RS19725
gene id: 706587:DESTI_RS19725
uniprot id: I4CAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

706587:DESTI RS19930
gene id: 706587:DESTI_RS19930
uniprot id: I4CAR5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

706587:DESTI RS04115
gene id: 706587:DESTI_RS04115
uniprot id: I4C1W0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

706587:DESTI RS07835
gene id: 706587:DESTI_RS07835
uniprot id: I4C3Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS22525
gene id: 706587:DESTI_RS22525
uniprot id: I4CC85
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS26635
gene id: 706587:DESTI_RS26635
uniprot id: I4CEH0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

706587:DESTI RS08705
gene id: 706587:DESTI_RS08705
uniprot id: I4C4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS07610
gene id: 706587:DESTI_RS07610
uniprot id: I4C3U4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

706587:DESTI RS00315
gene id: 706587:DESTI_RS00315
uniprot id: I4BZS0
names: Similarity
messages: Belongs to the CarB family.

706587:DESTI RS21675
gene id: 706587:DESTI_RS21675
uniprot id: I4CBR2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS00290
gene id: 706587:DESTI_RS00290
uniprot id: I4BZR6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

706587:DESTI RS01135
gene id: 706587:DESTI_RS01135
uniprot id: I4C081
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS01685
gene id: 706587:DESTI_RS01685
uniprot id: I4C0I3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS20915
gene id: 706587:DESTI_RS20915
uniprot id: I4CBB1
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00505
gene id: 706587:DESTI_RS00505
uniprot id: I4BZV6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

706587:DESTI RS15420
gene id: 706587:DESTI_RS15420
uniprot id: I4C869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

706587:DESTI RS05175
gene id: 706587:DESTI_RS05175
uniprot id: I4C2G4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

706587:DESTI RS29175
gene id: 706587:DESTI_RS29175
uniprot id: I4CAV7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

706587:DESTI RS14235
gene id: 706587:DESTI_RS14235
uniprot id: I4C7J1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

706587:DESTI RS30710
gene id: 706587:DESTI_RS30710
uniprot id: I4C5Y2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

706587:DESTI RS08285
gene id: 706587:DESTI_RS08285
uniprot id: I4C477
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

706587:DESTI RS06205
gene id: 706587:DESTI_RS06205
uniprot id: I4C312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

706587:DESTI RS26465
gene id: 706587:DESTI_RS26465
uniprot id: I4CED7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

706587:DESTI RS05585
gene id: 706587:DESTI_RS05585
uniprot id: I4C2P3
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

706587:DESTI RS12940
gene id: 706587:DESTI_RS12940
uniprot id: I4C6T6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

706587:DESTI RS22060
gene id: 706587:DESTI_RS22060
uniprot id: I4CBY8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00615
gene id: 706587:DESTI_RS00615
uniprot id: I4BZX8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

706587:DESTI RS05430
gene id: 706587:DESTI_RS05430
uniprot id: I4C2L1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS21585
gene id: 706587:DESTI_RS21585
uniprot id: I4CBP4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS15340
gene id: 706587:DESTI_RS15340
uniprot id: I4C853
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

706587:DESTI RS02000
gene id: 706587:DESTI_RS02000
uniprot id: I4C0P4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

706587:DESTI RS27735
gene id: 706587:DESTI_RS27735
uniprot id: I4CF24
names: Similarity
messages: Belongs to the ycf81 family.

706587:DESTI RS15695
gene id: 706587:DESTI_RS15695
uniprot id: I4C8C2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

706587:DESTI RS06580
gene id: 706587:DESTI_RS06580
uniprot id: I4C388
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS26700
gene id: 706587:DESTI_RS26700
uniprot id: I4CEI2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS19845
gene id: 706587:DESTI_RS19845
uniprot id: I4CAP8
names: Similarity
messages: Belongs to the peptidase C56 family.

706587:DESTI RS27135
gene id: 706587:DESTI_RS27135
uniprot id: I4CER4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

706587:DESTI RS12890
gene id: 706587:DESTI_RS12890
uniprot id: I4C6S6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

706587:DESTI RS05865
gene id: 706587:DESTI_RS05865
uniprot id: I4C2U7
names: Similarity
messages: Belongs to the GSP E family.

706587:DESTI RS02725
gene id: 706587:DESTI_RS02725
uniprot id: I4C141
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

706587:DESTI RS08730
gene id: 706587:DESTI_RS08730
uniprot id: I4C4G4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS24520
gene id: 706587:DESTI_RS24520
uniprot id: I4CDB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

706587:DESTI RS09910
gene id: 706587:DESTI_RS09910
uniprot id: I4C544
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

706587:DESTI RS29325
gene id: 706587:DESTI_RS29325
uniprot id: I4CCD6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

706587:DESTI RS29125
gene id: 706587:DESTI_RS29125
uniprot id: I4C9Q0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

706587:DESTI RS08090
gene id: 706587:DESTI_RS08090
uniprot id: I4C437
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

706587:DESTI RS17855
gene id: 706587:DESTI_RS17855
uniprot id: I4C9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

706587:DESTI RS22150
gene id: 706587:DESTI_RS22150
uniprot id: I4CC09
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

706587:DESTI RS05470
gene id: 706587:DESTI_RS05470
uniprot id: I4C2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

706587:DESTI RS18350
gene id: 706587:DESTI_RS18350
uniprot id: I4C9U4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

706587:DESTI RS26060
gene id: 706587:DESTI_RS26060
uniprot id: I4CE51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

706587:DESTI RS28000
gene id: 706587:DESTI_RS28000
uniprot id: I4CF77
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

706587:DESTI RS27340
gene id: 706587:DESTI_RS27340
uniprot id: I4CEU8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS13645
gene id: 706587:DESTI_RS13645
uniprot id: I4C779
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

706587:DESTI RS25400
gene id: 706587:DESTI_RS25400
uniprot id: I4CDT5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

706587:DESTI RS09235
gene id: 706587:DESTI_RS09235
uniprot id: I4C4R2
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS01315
gene id: 706587:DESTI_RS01315
uniprot id: I4C0B5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

706587:DESTI RS25085
gene id: 706587:DESTI_RS25085
uniprot id: I4CDM6
names: Similarity
messages: Belongs to the sulfatase family.

706587:DESTI RS18030
gene id: 706587:DESTI_RS18030
uniprot id: I4C9M9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

706587:DESTI RS07240
gene id: 706587:DESTI_RS07240
uniprot id: I4C3M0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

706587:DESTI RS24155
gene id: 706587:DESTI_RS24155
uniprot id: I4CD47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

706587:DESTI RS23580
gene id: 706587:DESTI_RS23580
uniprot id: I4CCT6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

706587:DESTI RS15885
gene id: 706587:DESTI_RS15885
uniprot id: I4C8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

706587:DESTI RS10350
gene id: 706587:DESTI_RS10350
uniprot id: I4C5C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

706587:DESTI RS24810
gene id: 706587:DESTI_RS24810
uniprot id: I4CDH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS03245
gene id: 706587:DESTI_RS03245
uniprot id: I4C1E0
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS23215
gene id: 706587:DESTI_RS23215
uniprot id: I4CCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS22970
gene id: 706587:DESTI_RS22970
uniprot id: I4CCH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

706587:DESTI RS06305
gene id: 706587:DESTI_RS06305
uniprot id: I4C333
names: Similarity
messages: Belongs to the phosphohexose mutase family.

706587:DESTI RS14830
gene id: 706587:DESTI_RS14830
uniprot id: I4C7V9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS14985
gene id: 706587:DESTI_RS14985
uniprot id: I4C7Y8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

706587:DESTI RS09640
gene id: 706587:DESTI_RS09640
uniprot id: I4C4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS27980
gene id: 706587:DESTI_RS27980
uniprot id: I4CF73
names: Similarity
messages: Belongs to the MEMO1 family.

706587:DESTI RS18555
gene id: 706587:DESTI_RS18555
uniprot id: I4C9Y5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS20970
gene id: 706587:DESTI_RS20970
uniprot id: I4CBC3
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

706587:DESTI RS15345
gene id: 706587:DESTI_RS15345
uniprot id: I4C854
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

706587:DESTI RS07565
gene id: 706587:DESTI_RS07565
uniprot id: I4C3T5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

706587:DESTI RS11025
gene id: 706587:DESTI_RS11025
uniprot id: I4C5Q3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS28310
gene id: 706587:DESTI_RS28310
uniprot id: I4C0U5
names: Subcellular Location Annotation
messages: Cell inner membrane

706587:DESTI RS19285
gene id: 706587:DESTI_RS19285
uniprot id: I4CAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

706587:DESTI RS20790
gene id: 706587:DESTI_RS20790
uniprot id: I4CB87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

706587:DESTI RS15515
gene id: 706587:DESTI_RS15515
uniprot id: I4C887
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

706587:DESTI RS19295
gene id: 706587:DESTI_RS19295
uniprot id: I4CAD4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

706587:DESTI RS29185
gene id: 706587:DESTI_RS29185
uniprot id: I4CAZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Membrane

706587:DESTI RS27830
gene id: 706587:DESTI_RS27830
uniprot id: I4CF42
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

706587:DESTI RS21550
gene id: 706587:DESTI_RS21550
uniprot id: I4CBN7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

706587:DESTI RS02880
gene id: 706587:DESTI_RS02880
uniprot id: I4C167
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

706587:DESTI RS04330
gene id: 706587:DESTI_RS04330
uniprot id: I4C200
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

706587:DESTI RS00825
gene id: 706587:DESTI_RS00825
uniprot id: I4C020
names: Similarity
messages: Belongs to the histone deacetylase family.

706587:DESTI RS18345
gene id: 706587:DESTI_RS18345
uniprot id: I4C9U3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS26135
gene id: 706587:DESTI_RS26135
uniprot id: I4CE67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

706587:DESTI RS27775
gene id: 706587:DESTI_RS27775
uniprot id: I4CF32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

706587:DESTI RS00385
gene id: 706587:DESTI_RS00385
uniprot id: I4BZT4
names: Similarity
messages: Belongs to the peptidase S41A family.

706587:DESTI RS27710
gene id: 706587:DESTI_RS27710
uniprot id: I4CF19
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

706587:DESTI RS17365
gene id: 706587:DESTI_RS17365
uniprot id: I4C9A3
names: Similarity
messages: Belongs to the RutC family.

706587:DESTI RS07215
gene id: 706587:DESTI_RS07215
uniprot id: I4C3L6
names: Similarity
messages: Belongs to the HdrA family.

706587:DESTI RS03405
gene id: 706587:DESTI_RS03405
uniprot id: I4C1H2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

706587:DESTI RS20370
gene id: 706587:DESTI_RS20370
uniprot id: I4CB03
names: Similarity
messages: Belongs to the HypE family.

706587:DESTI RS11540
gene id: 706587:DESTI_RS11540
uniprot id: I4C606
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

706587:DESTI RS20235
gene id: 706587:DESTI_RS20235
uniprot id: I4CAX4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20705
gene id: 706587:DESTI_RS20705
uniprot id: I4CB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS04280
gene id: 706587:DESTI_RS04280
uniprot id: I4C1Z0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

706587:DESTI RS23230
gene id: 706587:DESTI_RS23230
uniprot id: I4CCL9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

706587:DESTI RS09150
gene id: 706587:DESTI_RS09150
uniprot id: I4C4P5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

706587:DESTI RS17955
gene id: 706587:DESTI_RS17955
uniprot id: I4C9L5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS08085
gene id: 706587:DESTI_RS08085
uniprot id: I4C436
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

706587:DESTI RS18045
gene id: 706587:DESTI_RS18045
uniprot id: I4C9N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

706587:DESTI RS11890
gene id: 706587:DESTI_RS11890
uniprot id: I4C672
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

706587:DESTI RS26040
gene id: 706587:DESTI_RS26040
uniprot id: I4CE47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

706587:DESTI RS23275
gene id: 706587:DESTI_RS23275
uniprot id: I4CCM7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

706587:DESTI RS17915
gene id: 706587:DESTI_RS17915
uniprot id: I4C9K8
names: Similarity
messages: Belongs to the Ahb/Nir family.

706587:DESTI RS00990
gene id: 706587:DESTI_RS00990
uniprot id: I4C054
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

706587:DESTI RS31570
gene id: 706587:DESTI_RS31570
uniprot id: I4C1H5
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

706587:DESTI RS10695
gene id: 706587:DESTI_RS10695
uniprot id: I4C5I9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18735
gene id: 706587:DESTI_RS18735
uniprot id: I4CA23
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

706587:DESTI RS04775
gene id: 706587:DESTI_RS04775
uniprot id: I4C283
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

706587:DESTI RS03230
gene id: 706587:DESTI_RS03230
uniprot id: I4C1D7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS14415
gene id: 706587:DESTI_RS14415
uniprot id: I4C7M3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS20550
gene id: 706587:DESTI_RS20550
uniprot id: I4CB39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

706587:DESTI RS15150
gene id: 706587:DESTI_RS15150
uniprot id: I4C818
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS27765
gene id: 706587:DESTI_RS27765
uniprot id: I4CF30
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

706587:DESTI RS02245
gene id: 706587:DESTI_RS02245
uniprot id: I4C0U3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS09465
gene id: 706587:DESTI_RS09465
uniprot id: I4C4V8
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS16375
gene id: 706587:DESTI_RS16375
uniprot id: I4C8Q6
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

706587:DESTI RS09600
gene id: 706587:DESTI_RS09600
uniprot id: I4C4Y5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

706587:DESTI RS15790
gene id: 706587:DESTI_RS15790
uniprot id: I4C8E1
names: Subunit
messages: Homodimer.

706587:DESTI RS20085
gene id: 706587:DESTI_RS20085
uniprot id: I4CAU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

706587:DESTI RS04940
gene id: 706587:DESTI_RS04940
uniprot id: I4C2B5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS31470
gene id: 706587:DESTI_RS31470
uniprot id: I4CCP4
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS13030
gene id: 706587:DESTI_RS13030
uniprot id: I4C6V6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

706587:DESTI RS11275
gene id: 706587:DESTI_RS11275
uniprot id: I4C5V2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS31395
gene id: 706587:DESTI_RS31395
uniprot id: I4C826
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

706587:DESTI RS18320
gene id: 706587:DESTI_RS18320
uniprot id: I4C9T8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

706587:DESTI RS18235
gene id: 706587:DESTI_RS18235
uniprot id: I4C9S0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

706587:DESTI RS09535
gene id: 706587:DESTI_RS09535
uniprot id: I4C4X4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

706587:DESTI RS01975
gene id: 706587:DESTI_RS01975
uniprot id: I4C0P0
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

706587:DESTI RS19750
gene id: 706587:DESTI_RS19750
uniprot id: I4CAM9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS27495
gene id: 706587:DESTI_RS27495
uniprot id: I4CEX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

706587:DESTI RS17375
gene id: 706587:DESTI_RS17375
uniprot id: I4C9A5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS21820
gene id: 706587:DESTI_RS21820
uniprot id: I4CF08
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

706587:DESTI RS07905
gene id: 706587:DESTI_RS07905
uniprot id: I4C400
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

706587:DESTI RS10580
gene id: 706587:DESTI_RS10580
uniprot id: I4C5G9
names: Similarity
messages: Belongs to the transketolase family.

706587:DESTI RS27740
gene id: 706587:DESTI_RS27740
uniprot id: I4CF25
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

706587:DESTI RS06125
gene id: 706587:DESTI_RS06125
uniprot id: I4C2Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS15635
gene id: 706587:DESTI_RS15635
uniprot id: I4C8B0
names: Similarity
messages: Belongs to the transketolase family.

706587:DESTI RS19730
gene id: 706587:DESTI_RS19730
uniprot id: I4CAM5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS13410
gene id: 706587:DESTI_RS13410
uniprot id: I4C734
names: Similarity
messages: Belongs to the RutC family.

706587:DESTI RS24070
gene id: 706587:DESTI_RS24070
uniprot id: I4CD31
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

706587:DESTI RS02660
gene id: 706587:DESTI_RS02660
uniprot id: I4C126
names: Similarity
messages: Belongs to the pyruvate kinase family.

706587:DESTI RS26220
gene id: 706587:DESTI_RS26220
uniprot id: I4CE85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

706587:DESTI RS19150
gene id: 706587:DESTI_RS19150
uniprot id: I4CAA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

706587:DESTI RS23930
gene id: 706587:DESTI_RS23930
uniprot id: I4CD04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS14260
gene id: 706587:DESTI_RS14260
uniprot id: I4C7J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

706587:DESTI RS00895
gene id: 706587:DESTI_RS00895
uniprot id: I4C033
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS06910
gene id: 706587:DESTI_RS06910
uniprot id: I4C3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

706587:DESTI RS28635
gene id: 706587:DESTI_RS28635
uniprot id: I4C4J6
names: Subcellular Location Annotation
messages: Cell inner membrane

706587:DESTI RS17920
gene id: 706587:DESTI_RS17920
uniprot id: I4C9K9
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

706587:DESTI RS14865
gene id: 706587:DESTI_RS14865
uniprot id: I4C7W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

706587:DESTI RS09300
gene id: 706587:DESTI_RS09300
uniprot id: I4C4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

706587:DESTI RS24200
gene id: 706587:DESTI_RS24200
uniprot id: I4CD56
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS14175
gene id: 706587:DESTI_RS14175
uniprot id: I4C7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

706587:DESTI RS17620
gene id: 706587:DESTI_RS17620
uniprot id: I4C9F2
names: Similarity
messages: Belongs to the peptidase C56 family.

706587:DESTI RS28110
gene id: 706587:DESTI_RS28110
uniprot id: I4CF99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

706587:DESTI RS16720
gene id: 706587:DESTI_RS16720
uniprot id: I4C8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

706587:DESTI RS13180
gene id: 706587:DESTI_RS13180
uniprot id: I4C6Y8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

706587:DESTI RS09345
gene id: 706587:DESTI_RS09345
uniprot id: I4C4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

706587:DESTI RS20775
gene id: 706587:DESTI_RS20775
uniprot id: I4CB84
names: Similarity
messages: Belongs to the malic enzymes family.

706587:DESTI RS08045
gene id: 706587:DESTI_RS08045
uniprot id: I4C427
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

706587:DESTI RS14595
gene id: 706587:DESTI_RS14595
uniprot id: I4C7R2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

706587:DESTI RS24555
gene id: 706587:DESTI_RS24555
uniprot id: I4CDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

706587:DESTI RS23835
gene id: 706587:DESTI_RS23835
uniprot id: I4CCY3
names: Subunit
messages: Heterodimer of a large and a small subunit.

706587:DESTI RS24950
gene id: 706587:DESTI_RS24950
uniprot id: I4CDK0
names: Similarity
messages: Belongs to the HdrA family.

706587:DESTI RS25320
gene id: 706587:DESTI_RS25320
uniprot id: I4CDS2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

706587:DESTI RS01110
gene id: 706587:DESTI_RS01110
uniprot id: I4C076
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

706587:DESTI RS26370
gene id: 706587:DESTI_RS26370
uniprot id: I4CEB6
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS15570
gene id: 706587:DESTI_RS15570
uniprot id: I4C898
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

706587:DESTI RS27510
gene id: 706587:DESTI_RS27510
uniprot id: I4CEY0
names: Similarity
messages: Belongs to the class-I fumarase family.

706587:DESTI RS28015
gene id: 706587:DESTI_RS28015
uniprot id: I4CF80
names: Similarity
messages: Belongs to the ParB family.

706587:DESTI RS07670
gene id: 706587:DESTI_RS07670
uniprot id: I4C3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

706587:DESTI RS02005
gene id: 706587:DESTI_RS02005
uniprot id: I4C0P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

706587:DESTI RS01180
gene id: 706587:DESTI_RS01180
uniprot id: I4C089
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

706587:DESTI RS02790
gene id: 706587:DESTI_RS02790
uniprot id: I4C149
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

706587:DESTI RS12880
gene id: 706587:DESTI_RS12880
uniprot id: I4C6S4
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

706587:DESTI RS24695
gene id: 706587:DESTI_RS24695
uniprot id: I4CDE9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS10655
gene id: 706587:DESTI_RS10655
uniprot id: I4C5I3
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS04050
gene id: 706587:DESTI_RS04050
uniprot id: I4C1U8
names: Subcellular Location Annotation
messages: Secreted

706587:DESTI RS19620
gene id: 706587:DESTI_RS19620
uniprot id: I4CAK2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

706587:DESTI RS16640
gene id: 706587:DESTI_RS16640
uniprot id: I4C8W0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

706587:DESTI RS01375
gene id: 706587:DESTI_RS01375
uniprot id: I4C0C5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS24300
gene id: 706587:DESTI_RS24300
uniprot id: I4CD75
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS00600
gene id: 706587:DESTI_RS00600
uniprot id: I4BZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

706587:DESTI RS15540
gene id: 706587:DESTI_RS15540
uniprot id: I4C892
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS09985
gene id: 706587:DESTI_RS09985
uniprot id: I4C558
names: Similarity
names: Subunit
messages: Belongs to the leucine-binding protein family.
messages: Heterodimer of a large and a small subunit.

706587:DESTI RS26900
gene id: 706587:DESTI_RS26900
uniprot id: I4CEM4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS17805
gene id: 706587:DESTI_RS17805
uniprot id: I4C9I8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

706587:DESTI RS21695
gene id: 706587:DESTI_RS21695
uniprot id: I4CBR6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

706587:DESTI RS12800
gene id: 706587:DESTI_RS12800
uniprot id: I4C6Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

706587:DESTI RS03755
gene id: 706587:DESTI_RS03755
uniprot id: I4C1P0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

706587:DESTI RS08830
gene id: 706587:DESTI_RS08830
uniprot id: I4C4I3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

706587:DESTI RS24985
gene id: 706587:DESTI_RS24985
uniprot id: I4CDK7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

706587:DESTI RS21490
gene id: 706587:DESTI_RS21490
uniprot id: I4CBM5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS13405
gene id: 706587:DESTI_RS13405
uniprot id: I4C733
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

706587:DESTI RS20160
gene id: 706587:DESTI_RS20160
uniprot id: I4CAW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

706587:DESTI RS05975
gene id: 706587:DESTI_RS05975
uniprot id: I4C2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

706587:DESTI RS26080
gene id: 706587:DESTI_RS26080
uniprot id: I4CE56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

706587:DESTI RS19055
gene id: 706587:DESTI_RS19055
uniprot id: I4CA83
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

706587:DESTI RS26620
gene id: 706587:DESTI_RS26620
uniprot id: I4CEG7
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS14890
gene id: 706587:DESTI_RS14890
uniprot id: I4C7W8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

706587:DESTI RS19260
gene id: 706587:DESTI_RS19260
uniprot id: I4CAC6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

706587:DESTI RS12865
gene id: 706587:DESTI_RS12865
uniprot id: I4C6S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

706587:DESTI RS04740
gene id: 706587:DESTI_RS04740
uniprot id: I4C275
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS18675
gene id: 706587:DESTI_RS18675
uniprot id: I4CA10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

706587:DESTI RS27240
gene id: 706587:DESTI_RS27240
uniprot id: I4CET2
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

706587:DESTI RS04185
gene id: 706587:DESTI_RS04185
uniprot id: I4C1X4
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

706587:DESTI RS26115
gene id: 706587:DESTI_RS26115
uniprot id: I4CE63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

706587:DESTI RS12720
gene id: 706587:DESTI_RS12720
uniprot id: I4C6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

706587:DESTI RS14660
gene id: 706587:DESTI_RS14660
uniprot id: I4C7S5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

706587:DESTI RS19160
gene id: 706587:DESTI_RS19160
uniprot id: I4CAA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

706587:DESTI RS19865
gene id: 706587:DESTI_RS19865
uniprot id: I4CAQ2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

706587:DESTI RS18155
gene id: 706587:DESTI_RS18155
uniprot id: I4C9Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS20405
gene id: 706587:DESTI_RS20405
uniprot id: I4CB10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

706587:DESTI RS07120
gene id: 706587:DESTI_RS07120
uniprot id: I4C3J7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

706587:DESTI RS18750
gene id: 706587:DESTI_RS18750
uniprot id: I4CA25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

706587:DESTI RS07885
gene id: 706587:DESTI_RS07885
uniprot id: I4C3Z6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS04645
gene id: 706587:DESTI_RS04645
uniprot id: I4C255
names: Similarity
messages: Belongs to the asparagine synthetase family.

706587:DESTI RS21615
gene id: 706587:DESTI_RS21615
uniprot id: I4CBP9
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

706587:DESTI RS20440
gene id: 706587:DESTI_RS20440
uniprot id: I4CB17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

706587:DESTI RS01660
gene id: 706587:DESTI_RS01660
uniprot id: I4C0H7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

706587:DESTI RS14290
gene id: 706587:DESTI_RS14290
uniprot id: I4C7K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

706587:DESTI RS04850
gene id: 706587:DESTI_RS04850
uniprot id: I4C296
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

706587:DESTI RS10740
gene id: 706587:DESTI_RS10740
uniprot id: I4C5J9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS26915
gene id: 706587:DESTI_RS26915
uniprot id: I4CEM7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

706587:DESTI RS06550
gene id: 706587:DESTI_RS06550
uniprot id: I4C382
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

706587:DESTI RS27015
gene id: 706587:DESTI_RS27015
uniprot id: I4CEP4
names: Similarity
messages: Belongs to the MtrH family.

706587:DESTI RS19350
gene id: 706587:DESTI_RS19350
uniprot id: I4CAE5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

706587:DESTI RS13975
gene id: 706587:DESTI_RS13975
uniprot id: I4C7D9
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS12360
gene id: 706587:DESTI_RS12360
uniprot id: I4C6G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

706587:DESTI RS00260
gene id: 706587:DESTI_RS00260
uniprot id: I4BZR0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

706587:DESTI RS23430
gene id: 706587:DESTI_RS23430
uniprot id: I4CCQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

706587:DESTI RS07175
gene id: 706587:DESTI_RS07175
uniprot id: I4C3K8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

706587:DESTI RS03750
gene id: 706587:DESTI_RS03750
uniprot id: I4C1N9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

706587:DESTI RS09240
gene id: 706587:DESTI_RS09240
uniprot id: I4C4R3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS02405
gene id: 706587:DESTI_RS02405
uniprot id: I4C0X5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS19740
gene id: 706587:DESTI_RS19740
uniprot id: I4CAM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

706587:DESTI RS03690
gene id: 706587:DESTI_RS03690
uniprot id: I4C1M7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

706587:DESTI RS24150
gene id: 706587:DESTI_RS24150
uniprot id: I4CD46
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

706587:DESTI RS17940
gene id: 706587:DESTI_RS17940
uniprot id: I4C9L3
names: Similarity
messages: Belongs to the P(II) protein family.

706587:DESTI RS17540
gene id: 706587:DESTI_RS17540
uniprot id: I4C9D5
names: Subcellular Location Annotation
messages: Membrane

706587:DESTI RS20890
gene id: 706587:DESTI_RS20890
uniprot id: I4CBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

706587:DESTI RS12700
gene id: 706587:DESTI_RS12700
uniprot id: I4C6N4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm