697329:RUMAL RS17440
gene id: 697329:RUMAL_RS17440
uniprot id: E6UJM5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

697329:RUMAL RS10110
gene id: 697329:RUMAL_RS10110
uniprot id: E6UAR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

697329:RUMAL RS09970
gene id: 697329:RUMAL_RS09970
uniprot id: E6UAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

697329:RUMAL RS13025
gene id: 697329:RUMAL_RS13025
uniprot id: E6UFQ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

697329:RUMAL RS16250
gene id: 697329:RUMAL_RS16250
uniprot id: E6UFZ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

697329:RUMAL RS15780
gene id: 697329:RUMAL_RS15780
uniprot id: E6UF48
names: Similarity
messages: Belongs to the HisA/HisF family.

697329:RUMAL RS14035
gene id: 697329:RUMAL_RS14035
uniprot id: E6UHU2
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

697329:RUMAL RS16520
gene id: 697329:RUMAL_RS16520
uniprot id: E6UGQ9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

697329:RUMAL RS16495
gene id: 697329:RUMAL_RS16495
uniprot id: E6UGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

697329:RUMAL RS15985
gene id: 697329:RUMAL_RS15985
uniprot id: E6UF89
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

697329:RUMAL RS12580
gene id: 697329:RUMAL_RS12580
uniprot id: E6UEW3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

697329:RUMAL RS14360
gene id: 697329:RUMAL_RS14360
uniprot id: E6UI06
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

697329:RUMAL RS04360
gene id: 697329:RUMAL_RS04360
uniprot id: E6UIS7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Both RaMP1 and RaMP2 (Rumal_0099) catalyze the phosphorolysis of a beta-1,4-mannosidic linkage at the non-reducing end of a substrate, but acceptor specificities are clearly different.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose. Involved in a mannan catabolic pathway which feeds into glycolysis.
messages: Homodimer in solution.

697329:RUMAL RS12030
gene id: 697329:RUMAL_RS12030
uniprot id: E6UDH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

697329:RUMAL RS09960
gene id: 697329:RUMAL_RS09960
uniprot id: E6UAN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

697329:RUMAL RS01310
gene id: 697329:RUMAL_RS01310
uniprot id: E6UD22
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

697329:RUMAL RS20170
gene id: 697329:RUMAL_RS20170
uniprot id: E6UL46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

697329:RUMAL RS05975
gene id: 697329:RUMAL_RS05975
uniprot id: E6UD92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

697329:RUMAL RS02230
gene id: 697329:RUMAL_RS02230
uniprot id: E6UFA2
names: Similarity
messages: Belongs to the EamA transporter family.

697329:RUMAL RS06450
gene id: 697329:RUMAL_RS06450
uniprot id: E6UBX6
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

697329:RUMAL RS11120
gene id: 697329:RUMAL_RS11120
uniprot id: E6UC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS03385
gene id: 697329:RUMAL_RS03385
uniprot id: E6UHG7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

697329:RUMAL RS13255
gene id: 697329:RUMAL_RS13255
uniprot id: E6UGG0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

697329:RUMAL RS20165
gene id: 697329:RUMAL_RS20165
uniprot id: E6UL45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

697329:RUMAL RS01205
gene id: 697329:RUMAL_RS01205
uniprot id: E6UD01
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

697329:RUMAL RS00315
gene id: 697329:RUMAL_RS00315
uniprot id: E6UBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

697329:RUMAL RS17185
gene id: 697329:RUMAL_RS17185
uniprot id: E6UJI2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

697329:RUMAL RS02400
gene id: 697329:RUMAL_RS02400
uniprot id: E6UFD6
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS12085
gene id: 697329:RUMAL_RS12085
uniprot id: E6UDI5
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

697329:RUMAL RS11890
gene id: 697329:RUMAL_RS11890
uniprot id: E6UDE5
names: Subunit
messages: Homodimer.

697329:RUMAL RS12735
gene id: 697329:RUMAL_RS12735
uniprot id: E6UEZ4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

697329:RUMAL RS18420
gene id: 697329:RUMAL_RS18420
uniprot id: E6UK63
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

697329:RUMAL RS16780
gene id: 697329:RUMAL_RS16780
uniprot id: E6UJB4
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS10615
gene id: 697329:RUMAL_RS10615
uniprot id: E6UBG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS03595
gene id: 697329:RUMAL_RS03595
uniprot id: E6UHK5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

697329:RUMAL RS00865
gene id: 697329:RUMAL_RS00865
uniprot id: E6UCD8
names: Similarity
messages: Belongs to the peptidase S8 family.

697329:RUMAL RS12450
gene id: 697329:RUMAL_RS12450
uniprot id: E6UE75
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS15500
gene id: 697329:RUMAL_RS15500
uniprot id: E6UED1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

697329:RUMAL RS11040
gene id: 697329:RUMAL_RS11040
uniprot id: E6UC43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

697329:RUMAL RS08850
gene id: 697329:RUMAL_RS08850
uniprot id: E6UIX2
names: Similarity
messages: Belongs to the peptidase S66 family.

697329:RUMAL RS13200
gene id: 697329:RUMAL_RS13200
uniprot id: E6UFT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS05305
gene id: 697329:RUMAL_RS05305
uniprot id: E6UC21
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

697329:RUMAL RS00465
gene id: 697329:RUMAL_RS00465
uniprot id: E6UBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

697329:RUMAL RS05210
gene id: 697329:RUMAL_RS05210
uniprot id: E6UC03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

697329:RUMAL RS19115
gene id: 697329:RUMAL_RS19115
uniprot id: E6UKK0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

697329:RUMAL RS09825
gene id: 697329:RUMAL_RS09825
uniprot id: E6UAL0
names: Similarity
messages: Belongs to the thioesterase family.

697329:RUMAL RS18885
gene id: 697329:RUMAL_RS18885
uniprot id: E6UKF6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

697329:RUMAL RS02370
gene id: 697329:RUMAL_RS02370
uniprot id: E6UFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS10945
gene id: 697329:RUMAL_RS10945
uniprot id: E6UC24
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

697329:RUMAL RS00355
gene id: 697329:RUMAL_RS00355
uniprot id: E6UBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

697329:RUMAL RS08305
gene id: 697329:RUMAL_RS08305
uniprot id: E6UHT1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

697329:RUMAL RS03080
gene id: 697329:RUMAL_RS03080
uniprot id: E6UGX0
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS06410
gene id: 697329:RUMAL_RS06410
uniprot id: E6UDZ2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

697329:RUMAL RS00870
gene id: 697329:RUMAL_RS00870
uniprot id: E6UCD9
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS03120
gene id: 697329:RUMAL_RS03120
uniprot id: E6UGX8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

697329:RUMAL RS14325
gene id: 697329:RUMAL_RS14325
uniprot id: E6UHZ9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

697329:RUMAL RS05070
gene id: 697329:RUMAL_RS05070
uniprot id: E6UBX3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

697329:RUMAL RS11995
gene id: 697329:RUMAL_RS11995
uniprot id: E6UDG6
names: Similarity
messages: Belongs to the UPF0297 family.

697329:RUMAL RS09760
gene id: 697329:RUMAL_RS09760
uniprot id: E6UAJ7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

697329:RUMAL RS01245
gene id: 697329:RUMAL_RS01245
uniprot id: E6UD09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

697329:RUMAL RS12830
gene id: 697329:RUMAL_RS12830
uniprot id: E6UF09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

697329:RUMAL RS09585
gene id: 697329:RUMAL_RS09585
uniprot id: E6UAG5
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS13435
gene id: 697329:RUMAL_RS13435
uniprot id: E6UGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

697329:RUMAL RS03185
gene id: 697329:RUMAL_RS03185
uniprot id: E6UGY9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

697329:RUMAL RS07665
gene id: 697329:RUMAL_RS07665
uniprot id: E6UH13
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS12100
gene id: 697329:RUMAL_RS12100
uniprot id: E6UE06
names: Similarity
messages: Belongs to the GSP E family.

697329:RUMAL RS15970
gene id: 697329:RUMAL_RS15970
uniprot id: E6UF86
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

697329:RUMAL RS14175
gene id: 697329:RUMAL_RS14175
uniprot id: E6UHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS20290
gene id: 697329:RUMAL_RS20290
uniprot id: E6UL72
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS18310
gene id: 697329:RUMAL_RS18310
uniprot id: E6UK41
names: Similarity
messages: Belongs to the polysaccharide synthase family.

697329:RUMAL RS10695
gene id: 697329:RUMAL_RS10695
uniprot id: E6UBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

697329:RUMAL RS05455
gene id: 697329:RUMAL_RS05455
uniprot id: E6UCJ6
names: Similarity
messages: Belongs to the peptidase S66 family.

697329:RUMAL RS12470
gene id: 697329:RUMAL_RS12470
uniprot id: E6UEU5
names: Similarity
messages: Belongs to the polypeptide deformylase family.

697329:RUMAL RS04625
gene id: 697329:RUMAL_RS04625
uniprot id: E6UB83
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

697329:RUMAL RS22315
gene id: 697329:RUMAL_RS22315
uniprot id: E6UFE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

697329:RUMAL RS05140
gene id: 697329:RUMAL_RS05140
uniprot id: E6UBY8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

697329:RUMAL RS13550
gene id: 697329:RUMAL_RS13550
uniprot id: E6UGL9
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

697329:RUMAL RS04805
gene id: 697329:RUMAL_RS04805
uniprot id: E6UBB7
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS15385
gene id: 697329:RUMAL_RS15385
uniprot id: E6UEA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

697329:RUMAL RS15675
gene id: 697329:RUMAL_RS15675
uniprot id: E6UF27
names: Similarity
messages: Belongs to the Nudix hydrolase family.

697329:RUMAL RS13465
gene id: 697329:RUMAL_RS13465
uniprot id: E6UGK1
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

697329:RUMAL RS19080
gene id: 697329:RUMAL_RS19080
uniprot id: E6UKJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

697329:RUMAL RS10495
gene id: 697329:RUMAL_RS10495
uniprot id: E6UB17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

697329:RUMAL RS11265
gene id: 697329:RUMAL_RS11265
uniprot id: E6UC89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

697329:RUMAL RS14840
gene id: 697329:RUMAL_RS14840
uniprot id: E6UJ42
names: Similarity
messages: Belongs to the phosphohexose mutase family.

697329:RUMAL RS07895
gene id: 697329:RUMAL_RS07895
uniprot id: E6UH56
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS01200
gene id: 697329:RUMAL_RS01200
uniprot id: E6UD00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

697329:RUMAL RS06725
gene id: 697329:RUMAL_RS06725
uniprot id: E6UES3
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

697329:RUMAL RS05265
gene id: 697329:RUMAL_RS05265
uniprot id: E6UC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

697329:RUMAL RS07250
gene id: 697329:RUMAL_RS07250
uniprot id: E6UGA0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS18830
gene id: 697329:RUMAL_RS18830
uniprot id: E6UKE4
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS16670
gene id: 697329:RUMAL_RS16670
uniprot id: E6UGT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

697329:RUMAL RS09230
gene id: 697329:RUMAL_RS09230
uniprot id: E6UA93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

697329:RUMAL RS00325
gene id: 697329:RUMAL_RS00325
uniprot id: E6UBN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

697329:RUMAL RS10555
gene id: 697329:RUMAL_RS10555
uniprot id: E6UBF6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

697329:RUMAL RS12275
gene id: 697329:RUMAL_RS12275
uniprot id: E6UE41
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

697329:RUMAL RS09990
gene id: 697329:RUMAL_RS09990
uniprot id: E6UAP1
names: Similarity
messages: Belongs to the asp23 family.

697329:RUMAL RS09205
gene id: 697329:RUMAL_RS09205
uniprot id: E6UA88
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

697329:RUMAL RS04620
gene id: 697329:RUMAL_RS04620
uniprot id: E6UB82
names: Similarity
messages: Belongs to the serpin family.

697329:RUMAL RS09930
gene id: 697329:RUMAL_RS09930
uniprot id: E6UAM9
names: Similarity
messages: Belongs to the thymidylate kinase family.

697329:RUMAL RS02365
gene id: 697329:RUMAL_RS02365
uniprot id: E6UFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS10600
gene id: 697329:RUMAL_RS10600
uniprot id: E6UBG2
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.

697329:RUMAL RS15810
gene id: 697329:RUMAL_RS15810
uniprot id: E6UF55
names: Similarity
messages: Belongs to the UPF0473 family.

697329:RUMAL RS10545
gene id: 697329:RUMAL_RS10545
uniprot id: E6UBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

697329:RUMAL RS08275
gene id: 697329:RUMAL_RS08275
uniprot id: E6UHS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS11805
gene id: 697329:RUMAL_RS11805
uniprot id: E6UDC8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

697329:RUMAL RS01530
gene id: 697329:RUMAL_RS01530
uniprot id: E6UDN3
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS20315
gene id: 697329:RUMAL_RS20315
uniprot id: E6UL78
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

697329:RUMAL RS09860
gene id: 697329:RUMAL_RS09860
uniprot id: E6UAL5
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

697329:RUMAL RS09925
gene id: 697329:RUMAL_RS09925
uniprot id: E6UAM8
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS05090
gene id: 697329:RUMAL_RS05090
uniprot id: E6UBX8
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS01525
gene id: 697329:RUMAL_RS01525
uniprot id: E6UDN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

697329:RUMAL RS09940
gene id: 697329:RUMAL_RS09940
uniprot id: E6UAN1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

697329:RUMAL RS07745
gene id: 697329:RUMAL_RS07745
uniprot id: E6UH29
names: Similarity
messages: Belongs to the asparagine synthetase family.

697329:RUMAL RS09060
gene id: 697329:RUMAL_RS09060
uniprot id: E6UJ15
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

697329:RUMAL RS14385
gene id: 697329:RUMAL_RS14385
uniprot id: E6UIF3
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS10745
gene id: 697329:RUMAL_RS10745
uniprot id: E6UBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

697329:RUMAL RS04705
gene id: 697329:RUMAL_RS04705
uniprot id: E6UB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

697329:RUMAL RS07995
gene id: 697329:RUMAL_RS07995
uniprot id: E6UHL9
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

697329:RUMAL RS20080
gene id: 697329:RUMAL_RS20080
uniprot id: E6UL27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

697329:RUMAL RS00475
gene id: 697329:RUMAL_RS00475
uniprot id: E6UBR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

697329:RUMAL RS15265
gene id: 697329:RUMAL_RS15265
uniprot id: E6UE84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

697329:RUMAL RS05910
gene id: 697329:RUMAL_RS05910
uniprot id: E6UD79
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

697329:RUMAL RS05410
gene id: 697329:RUMAL_RS05410
uniprot id: E6UCI7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS10955
gene id: 697329:RUMAL_RS10955
uniprot id: E6UC26
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

697329:RUMAL RS00170
gene id: 697329:RUMAL_RS00170
uniprot id: E6UB54
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

697329:RUMAL RS03785
gene id: 697329:RUMAL_RS03785
uniprot id: E6UI27
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

697329:RUMAL RS16105
gene id: 697329:RUMAL_RS16105
uniprot id: E6UFW5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

697329:RUMAL RS08085
gene id: 697329:RUMAL_RS08085
uniprot id: E6UHN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

697329:RUMAL RS15525
gene id: 697329:RUMAL_RS15525
uniprot id: E6UED6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

697329:RUMAL RS02135
gene id: 697329:RUMAL_RS02135
uniprot id: E6UEM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

697329:RUMAL RS10775
gene id: 697329:RUMAL_RS10775
uniprot id: E6UBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

697329:RUMAL RS08375
gene id: 697329:RUMAL_RS08375
uniprot id: E6UI83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

697329:RUMAL RS00470
gene id: 697329:RUMAL_RS00470
uniprot id: E6UBR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS14355
gene id: 697329:RUMAL_RS14355
uniprot id: E6UI05
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS00375
gene id: 697329:RUMAL_RS00375
uniprot id: E6UBP2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

697329:RUMAL RS08205
gene id: 697329:RUMAL_RS08205
uniprot id: E6UHQ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS08220
gene id: 697329:RUMAL_RS08220
uniprot id: E6UHR2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

697329:RUMAL RS18900
gene id: 697329:RUMAL_RS18900
uniprot id: E6UKF9
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

697329:RUMAL RS09255
gene id: 697329:RUMAL_RS09255
uniprot id: E6UA98
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS10430
gene id: 697329:RUMAL_RS10430
uniprot id: E6UB04
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

697329:RUMAL RS14850
gene id: 697329:RUMAL_RS14850
uniprot id: E6UJ44
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

697329:RUMAL RS12630
gene id: 697329:RUMAL_RS12630
uniprot id: E6UEX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

697329:RUMAL RS02290
gene id: 697329:RUMAL_RS02290
uniprot id: E6UFB3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

697329:RUMAL RS20040
gene id: 697329:RUMAL_RS20040
uniprot id: E6UL19
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

697329:RUMAL RS09800
gene id: 697329:RUMAL_RS09800
uniprot id: E6UAK5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

697329:RUMAL RS15590
gene id: 697329:RUMAL_RS15590
uniprot id: E6UEE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

697329:RUMAL RS00275
gene id: 697329:RUMAL_RS00275
uniprot id: E6UB74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

697329:RUMAL RS01935
gene id: 697329:RUMAL_RS01935
uniprot id: E6UEI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

697329:RUMAL RS16415
gene id: 697329:RUMAL_RS16415
uniprot id: E6UGN8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

697329:RUMAL RS10735
gene id: 697329:RUMAL_RS10735
uniprot id: E6UBI8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

697329:RUMAL RS15605
gene id: 697329:RUMAL_RS15605
uniprot id: E6UEF0
names: Similarity
messages: Belongs to the DprA/Smf family.

697329:RUMAL RS01470
gene id: 697329:RUMAL_RS01470
uniprot id: O50141
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

697329:RUMAL RS20735
gene id: 697329:RUMAL_RS20735
uniprot id: E6UHP8
names: Similarity
messages: Belongs to the peptidase S11 family.

697329:RUMAL RS14425
gene id: 697329:RUMAL_RS14425
uniprot id: E6UIG2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS16040
gene id: 697329:RUMAL_RS16040
uniprot id: E6UFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

697329:RUMAL RS07820
gene id: 697329:RUMAL_RS07820
uniprot id: E6UH42
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS12135
gene id: 697329:RUMAL_RS12135
uniprot id: E6UE13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS16270
gene id: 697329:RUMAL_RS16270
uniprot id: E6UFZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS13345
gene id: 697329:RUMAL_RS13345
uniprot id: E6UGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

697329:RUMAL RS06320
gene id: 697329:RUMAL_RS06320
uniprot id: E6UDX4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

697329:RUMAL RS12520
gene id: 697329:RUMAL_RS12520
uniprot id: E6UEV1
names: Similarity
messages: Belongs to the 'phage' integrase family.

697329:RUMAL RS06425
gene id: 697329:RUMAL_RS06425
uniprot id: E6UDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

697329:RUMAL RS16785
gene id: 697329:RUMAL_RS16785
uniprot id: E6UJB5
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS15100
gene id: 697329:RUMAL_RS15100
uniprot id: E6UJ94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

697329:RUMAL RS16160
gene id: 697329:RUMAL_RS16160
uniprot id: E6UFX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS10610
gene id: 697329:RUMAL_RS10610
uniprot id: E6UBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

697329:RUMAL RS00190
gene id: 697329:RUMAL_RS00190
uniprot id: E6UB57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

697329:RUMAL RS09855
gene id: 697329:RUMAL_RS09855
uniprot id: E6UAL4
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

697329:RUMAL RS10320
gene id: 697329:RUMAL_RS10320
uniprot id: E6UAY3
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS07695
gene id: 697329:RUMAL_RS07695
uniprot id: E6UH19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

697329:RUMAL RS16130
gene id: 697329:RUMAL_RS16130
uniprot id: E6UFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS07870
gene id: 697329:RUMAL_RS07870
uniprot id: E6UH51
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

697329:RUMAL RS09210
gene id: 697329:RUMAL_RS09210
uniprot id: E6UA89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

697329:RUMAL RS05345
gene id: 697329:RUMAL_RS05345
uniprot id: E6UCH4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

697329:RUMAL RS04895
gene id: 697329:RUMAL_RS04895
uniprot id: E6UBD7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

697329:RUMAL RS08870
gene id: 697329:RUMAL_RS08870
uniprot id: E6UIX6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

697329:RUMAL RS14800
gene id: 697329:RUMAL_RS14800
uniprot id: E6UJ34
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS00020
gene id: 697329:RUMAL_RS00020
uniprot id: E6UB27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

697329:RUMAL RS13275
gene id: 697329:RUMAL_RS13275
uniprot id: E6UGG5
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS05120
gene id: 697329:RUMAL_RS05120
uniprot id: E6UBY4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

697329:RUMAL RS18735
gene id: 697329:RUMAL_RS18735
uniprot id: E6UKC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

697329:RUMAL RS03105
gene id: 697329:RUMAL_RS03105
uniprot id: E6UGX5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

697329:RUMAL RS13995
gene id: 697329:RUMAL_RS13995
uniprot id: E6UHE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

697329:RUMAL RS00215
gene id: 697329:RUMAL_RS00215
uniprot id: E6UB62
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

697329:RUMAL RS10805
gene id: 697329:RUMAL_RS10805
uniprot id: E6UBK2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

697329:RUMAL RS00855
gene id: 697329:RUMAL_RS00855
uniprot id: E6UCD0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

697329:RUMAL RS00300
gene id: 697329:RUMAL_RS00300
uniprot id: E6UBM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

697329:RUMAL RS13040
gene id: 697329:RUMAL_RS13040
uniprot id: E6UFQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS11115
gene id: 697329:RUMAL_RS11115
uniprot id: E6UC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS08465
gene id: 697329:RUMAL_RS08465
uniprot id: E6UIA1
names: Similarity
messages: Belongs to the DprA/Smf family.

697329:RUMAL RS16035
gene id: 697329:RUMAL_RS16035
uniprot id: E6UFV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

697329:RUMAL RS08720
gene id: 697329:RUMAL_RS08720
uniprot id: E6UIU8
names: Similarity
messages: Belongs to the TrpC family.

697329:RUMAL RS06435
gene id: 697329:RUMAL_RS06435
uniprot id: E6UDZ7
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

697329:RUMAL RS01535
gene id: 697329:RUMAL_RS01535
uniprot id: E6UDN4
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS14680
gene id: 697329:RUMAL_RS14680
uniprot id: E6UIL2
names: Similarity
messages: Belongs to the FemABX family.

697329:RUMAL RS15710
gene id: 697329:RUMAL_RS15710
uniprot id: E6UF34
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS12840
gene id: 697329:RUMAL_RS12840
uniprot id: E6UF11
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

697329:RUMAL RS11025
gene id: 697329:RUMAL_RS11025
uniprot id: E6UC40
names: Similarity
messages: Belongs to the UxaA family.

697329:RUMAL RS19035
gene id: 697329:RUMAL_RS19035
uniprot id: E6UKI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

697329:RUMAL RS05520
gene id: 697329:RUMAL_RS05520
uniprot id: E6UCK8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS01445
gene id: 697329:RUMAL_RS01445
uniprot id: E6UDL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

697329:RUMAL RS15830
gene id: 697329:RUMAL_RS15830
uniprot id: E6UF59
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

697329:RUMAL RS09340
gene id: 697329:RUMAL_RS09340
uniprot id: E6UAB5
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS04300
gene id: 697329:RUMAL_RS04300
uniprot id: E6UF02
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS09875
gene id: 697329:RUMAL_RS09875
uniprot id: E6UAL8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

697329:RUMAL RS16275
gene id: 697329:RUMAL_RS16275
uniprot id: E6UFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

697329:RUMAL RS16655
gene id: 697329:RUMAL_RS16655
uniprot id: E6UGS8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS18820
gene id: 697329:RUMAL_RS18820
uniprot id: E6UKE2
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS09150
gene id: 697329:RUMAL_RS09150
uniprot id: E6UA77
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

697329:RUMAL RS16310
gene id: 697329:RUMAL_RS16310
uniprot id: E6UG04
names: Similarity
messages: Belongs to the ParB family.

697329:RUMAL RS13135
gene id: 697329:RUMAL_RS13135
uniprot id: E6UFS2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

697329:RUMAL RS08605
gene id: 697329:RUMAL_RS08605
uniprot id: E6UID1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

697329:RUMAL RS01710
gene id: 697329:RUMAL_RS01710
uniprot id: E6UDR9
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS13565
gene id: 697329:RUMAL_RS13565
uniprot id: E6UGM2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

697329:RUMAL RS16045
gene id: 697329:RUMAL_RS16045
uniprot id: E6UFV4
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

697329:RUMAL RS04420
gene id: 697329:RUMAL_RS04420
uniprot id: E6UIU0
names: Similarity
messages: Belongs to the thioesterase family.

697329:RUMAL RS20995
gene id: 697329:RUMAL_RS20995
uniprot id: E6UJM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

697329:RUMAL RS11275
gene id: 697329:RUMAL_RS11275
uniprot id: E6UC91
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

697329:RUMAL RS01145
gene id: 697329:RUMAL_RS01145
uniprot id: E6UCZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS11260
gene id: 697329:RUMAL_RS11260
uniprot id: E6UC88
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

697329:RUMAL RS03355
gene id: 697329:RUMAL_RS03355
uniprot id: E6UHG1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS15945
gene id: 697329:RUMAL_RS15945
uniprot id: E6UF82
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

697329:RUMAL RS12945
gene id: 697329:RUMAL_RS12945
uniprot id: E6UFN4
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS22535
gene id: 697329:RUMAL_RS22535
uniprot id: E6UFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

697329:RUMAL RS11835
gene id: 697329:RUMAL_RS11835
uniprot id: E6UDD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

697329:RUMAL RS12990
gene id: 697329:RUMAL_RS12990
uniprot id: E6UFP3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

697329:RUMAL RS02675
gene id: 697329:RUMAL_RS02675
uniprot id: E6UG49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

697329:RUMAL RS04430
gene id: 697329:RUMAL_RS04430
uniprot id: E6UIU2
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS00105
gene id: 697329:RUMAL_RS00105
uniprot id: E6UB41
names: Function
names: Similarity
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

697329:RUMAL RS05360
gene id: 697329:RUMAL_RS05360
uniprot id: E6UCH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

697329:RUMAL RS06360
gene id: 697329:RUMAL_RS06360
uniprot id: E6UDY2
names: Similarity
messages: Belongs to the peptidase C40 family.

697329:RUMAL RS11855
gene id: 697329:RUMAL_RS11855
uniprot id: E6UDD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

697329:RUMAL RS15610
gene id: 697329:RUMAL_RS15610
uniprot id: E6UEF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

697329:RUMAL RS11590
gene id: 697329:RUMAL_RS11590
uniprot id: E6UCU5
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS12295
gene id: 697329:RUMAL_RS12295
uniprot id: E6UE45
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family.

697329:RUMAL RS09430
gene id: 697329:RUMAL_RS09430
uniprot id: E6UAD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

697329:RUMAL RS13930
gene id: 697329:RUMAL_RS13930
uniprot id: E6UHD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

697329:RUMAL RS08925
gene id: 697329:RUMAL_RS08925
uniprot id: E6UIY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

697329:RUMAL RS14125
gene id: 697329:RUMAL_RS14125
uniprot id: E6UHW0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

697329:RUMAL RS11010
gene id: 697329:RUMAL_RS11010
uniprot id: E6UC37
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS11765
gene id: 697329:RUMAL_RS11765
uniprot id: E6UDC0
names: Similarity
messages: Belongs to the peptidase S66 family.

697329:RUMAL RS15255
gene id: 697329:RUMAL_RS15255
uniprot id: E6UE82
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

697329:RUMAL RS12685
gene id: 697329:RUMAL_RS12685
uniprot id: E6UEY5
names: Similarity
messages: Belongs to the plasmid mobilization pre family.

697329:RUMAL RS04825
gene id: 697329:RUMAL_RS04825
uniprot id: E6UBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

697329:RUMAL RS05745
gene id: 697329:RUMAL_RS05745
uniprot id: E6UD49
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

697329:RUMAL RS20260
gene id: 697329:RUMAL_RS20260
uniprot id: E6UL64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

697329:RUMAL RS02795
gene id: 697329:RUMAL_RS02795
uniprot id: E6UG71
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

697329:RUMAL RS11225
gene id: 697329:RUMAL_RS11225
uniprot id: E6UC81
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS09185
gene id: 697329:RUMAL_RS09185
uniprot id: E6UA84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

697329:RUMAL RS08730
gene id: 697329:RUMAL_RS08730
uniprot id: E6UIV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

697329:RUMAL RS04135
gene id: 697329:RUMAL_RS04135
uniprot id: E6UIN8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS00330
gene id: 697329:RUMAL_RS00330
uniprot id: E6UBN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

697329:RUMAL RS08395
gene id: 697329:RUMAL_RS08395
uniprot id: E6UI87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

697329:RUMAL RS01480
gene id: 697329:RUMAL_RS01480
uniprot id: E6UDM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

697329:RUMAL RS08970
gene id: 697329:RUMAL_RS08970
uniprot id: E6UIZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

697329:RUMAL RS03390
gene id: 697329:RUMAL_RS03390
uniprot id: E6UHG9
names: Function
names: Similarity
messages: A P subtype restriction enzyme that recognizes the double-stranded unmethylated sequence 5'-GATC-3'.
messages: Belongs to the DpnII type II restriction endonuclease family.

697329:RUMAL RS01495
gene id: 697329:RUMAL_RS01495
uniprot id: E6UDM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

697329:RUMAL RS17625
gene id: 697329:RUMAL_RS17625
uniprot id: E6UJQ8
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS11155
gene id: 697329:RUMAL_RS11155
uniprot id: E6UC67
names: Function
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

697329:RUMAL RS00960
gene id: 697329:RUMAL_RS00960
uniprot id: E6UCF7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

697329:RUMAL RS09180
gene id: 697329:RUMAL_RS09180
uniprot id: E6UA83
names: Similarity
messages: Belongs to the RemA family.

697329:RUMAL RS20075
gene id: 697329:RUMAL_RS20075
uniprot id: E6UL26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

697329:RUMAL RS04410
gene id: 697329:RUMAL_RS04410
uniprot id: E6UIT8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

697329:RUMAL RS15975
gene id: 697329:RUMAL_RS15975
uniprot id: E6UF87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

697329:RUMAL RS10710
gene id: 697329:RUMAL_RS10710
uniprot id: E6UBI3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

697329:RUMAL RS16010
gene id: 697329:RUMAL_RS16010
uniprot id: E6UFU7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

697329:RUMAL RS01675
gene id: 697329:RUMAL_RS01675
uniprot id: E6UDR2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

697329:RUMAL RS02150
gene id: 697329:RUMAL_RS02150
uniprot id: E6UF92
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

697329:RUMAL RS07675
gene id: 697329:RUMAL_RS07675
uniprot id: E6UH15
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS16050
gene id: 697329:RUMAL_RS16050
uniprot id: E6UFV5
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

697329:RUMAL RS00415
gene id: 697329:RUMAL_RS00415
uniprot id: E6UBQ0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS09395
gene id: 697329:RUMAL_RS09395
uniprot id: E6UAC6
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

697329:RUMAL RS08315
gene id: 697329:RUMAL_RS08315
uniprot id: E6UHT3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

697329:RUMAL RS14320
gene id: 697329:RUMAL_RS14320
uniprot id: E6UHZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

697329:RUMAL RS00200
gene id: 697329:RUMAL_RS00200
uniprot id: E6UB59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

697329:RUMAL RS08590
gene id: 697329:RUMAL_RS08590
uniprot id: E6UIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

697329:RUMAL RS14220
gene id: 697329:RUMAL_RS14220
uniprot id: E6UHX9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

697329:RUMAL RS10455
gene id: 697329:RUMAL_RS10455
uniprot id: E6UB09
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

697329:RUMAL RS12570
gene id: 697329:RUMAL_RS12570
uniprot id: E6UEW1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

697329:RUMAL RS12635
gene id: 697329:RUMAL_RS12635
uniprot id: E6UEX5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

697329:RUMAL RS04325
gene id: 697329:RUMAL_RS04325
uniprot id: E6UIS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

697329:RUMAL RS09240
gene id: 697329:RUMAL_RS09240
uniprot id: E6UA95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS11585
gene id: 697329:RUMAL_RS11585
uniprot id: E6UCU4
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS02875
gene id: 697329:RUMAL_RS02875
uniprot id: E6UG86
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS05060
gene id: 697329:RUMAL_RS05060
uniprot id: E6UBX0
names: Similarity
messages: Belongs to the asparagine synthetase family.

697329:RUMAL RS00655
gene id: 697329:RUMAL_RS00655
uniprot id: E6UBU7
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS01315
gene id: 697329:RUMAL_RS01315
uniprot id: E6UD23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

697329:RUMAL RS16135
gene id: 697329:RUMAL_RS16135
uniprot id: E6UFX1
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS10460
gene id: 697329:RUMAL_RS10460
uniprot id: E6UB10
names: Similarity
messages: Belongs to the band 7/mec-2 family.

697329:RUMAL RS12005
gene id: 697329:RUMAL_RS12005
uniprot id: E6UDG8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

697329:RUMAL RS12370
gene id: 697329:RUMAL_RS12370
uniprot id: E6UE59
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

697329:RUMAL RS00405
gene id: 697329:RUMAL_RS00405
uniprot id: E6UBP8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

697329:RUMAL RS21070
gene id: 697329:RUMAL_RS21070
uniprot id: E6UKJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

697329:RUMAL RS00195
gene id: 697329:RUMAL_RS00195
uniprot id: E6UB58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

697329:RUMAL RS12330
gene id: 697329:RUMAL_RS12330
uniprot id: E6UE51
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

697329:RUMAL RS11840
gene id: 697329:RUMAL_RS11840
uniprot id: E6UDD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

697329:RUMAL RS12500
gene id: 697329:RUMAL_RS12500
uniprot id: E6UEU7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

697329:RUMAL RS13080
gene id: 697329:RUMAL_RS13080
uniprot id: E6UFR1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

697329:RUMAL RS01460
gene id: 697329:RUMAL_RS01460
uniprot id: O50143
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

697329:RUMAL RS06440
gene id: 697329:RUMAL_RS06440
uniprot id: E6UDZ8
names: Similarity
messages: Belongs to the GerABKA family.

697329:RUMAL RS06770
gene id: 697329:RUMAL_RS06770
uniprot id: E6UET2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

697329:RUMAL RS16120
gene id: 697329:RUMAL_RS16120
uniprot id: E6UFW8
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

697329:RUMAL RS08175
gene id: 697329:RUMAL_RS08175
uniprot id: E6UHQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

697329:RUMAL RS08575
gene id: 697329:RUMAL_RS08575
uniprot id: E6UIC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS00835
gene id: 697329:RUMAL_RS00835
uniprot id: E6UCC6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS14120
gene id: 697329:RUMAL_RS14120
uniprot id: E6UHV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS13010
gene id: 697329:RUMAL_RS13010
uniprot id: E6UFP7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

697329:RUMAL RS10225
gene id: 697329:RUMAL_RS10225
uniprot id: E6UAW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS08440
gene id: 697329:RUMAL_RS08440
uniprot id: E6UI96
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

697329:RUMAL RS10675
gene id: 697329:RUMAL_RS10675
uniprot id: E6UBH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS15400
gene id: 697329:RUMAL_RS15400
uniprot id: E6UEB1
names: Similarity
messages: Belongs to the RutC family.

697329:RUMAL RS10810
gene id: 697329:RUMAL_RS10810
uniprot id: E6UBK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

697329:RUMAL RS10130
gene id: 697329:RUMAL_RS10130
uniprot id: E6UAR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

697329:RUMAL RS09910
gene id: 697329:RUMAL_RS09910
uniprot id: E6UAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

697329:RUMAL RS19600
gene id: 697329:RUMAL_RS19600
uniprot id: E6UKT4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

697329:RUMAL RS02090
gene id: 697329:RUMAL_RS02090
uniprot id: E6UEL1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

697329:RUMAL RS09020
gene id: 697329:RUMAL_RS09020
uniprot id: E6UJ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

697329:RUMAL RS08135
gene id: 697329:RUMAL_RS08135
uniprot id: E6UHP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

697329:RUMAL RS05510
gene id: 697329:RUMAL_RS05510
uniprot id: E6UCK6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

697329:RUMAL RS18615
gene id: 697329:RUMAL_RS18615
uniprot id: E6UKA3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

697329:RUMAL RS04240
gene id: 697329:RUMAL_RS04240
uniprot id: E6UIQ7
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS12680
gene id: 697329:RUMAL_RS12680
uniprot id: E6UEY4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS00585
gene id: 697329:RUMAL_RS00585
uniprot id: E6UBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

697329:RUMAL RS15005
gene id: 697329:RUMAL_RS15005
uniprot id: E6UJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS14565
gene id: 697329:RUMAL_RS14565
uniprot id: E6UII8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

697329:RUMAL RS16795
gene id: 697329:RUMAL_RS16795
uniprot id: E6UJB7
names: Similarity
messages: Belongs to the peptidase A24 family.

697329:RUMAL RS20695
gene id: 697329:RUMAL_RS20695
uniprot id: E6UGE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

697329:RUMAL RS14245
gene id: 697329:RUMAL_RS14245
uniprot id: E6UHY4
names: Similarity
messages: Belongs to the CpsD/CapB family.

697329:RUMAL RS11875
gene id: 697329:RUMAL_RS11875
uniprot id: E6UDE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

697329:RUMAL RS00940
gene id: 697329:RUMAL_RS00940
uniprot id: E6UCF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS12310
gene id: 697329:RUMAL_RS12310
uniprot id: E6UE48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

697329:RUMAL RS20245
gene id: 697329:RUMAL_RS20245
uniprot id: E6UL61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

697329:RUMAL RS19405
gene id: 697329:RUMAL_RS19405
uniprot id: E6UKQ5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS04545
gene id: 697329:RUMAL_RS04545
uniprot id: E6UAT8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS00075
gene id: 697329:RUMAL_RS00075
uniprot id: E6UB36
names: Similarity
messages: Belongs to the ParB family.

697329:RUMAL RS04225
gene id: 697329:RUMAL_RS04225
uniprot id: E6UIQ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS10670
gene id: 697329:RUMAL_RS10670
uniprot id: E6UBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

697329:RUMAL RS15645
gene id: 697329:RUMAL_RS15645
uniprot id: E6UF21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

697329:RUMAL RS09480
gene id: 697329:RUMAL_RS09480
uniprot id: E6UAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS06280
gene id: 697329:RUMAL_RS06280
uniprot id: E6UDW6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS07165
gene id: 697329:RUMAL_RS07165
uniprot id: E6UFL8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

697329:RUMAL RS01045
gene id: 697329:RUMAL_RS01045
uniprot id: E6UCX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

697329:RUMAL RS14100
gene id: 697329:RUMAL_RS14100
uniprot id: E6UHV5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

697329:RUMAL RS06940
gene id: 697329:RUMAL_RS06940
uniprot id: E6UFH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS08390
gene id: 697329:RUMAL_RS08390
uniprot id: E6UI86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

697329:RUMAL RS15775
gene id: 697329:RUMAL_RS15775
uniprot id: E6UF47
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

697329:RUMAL RS10570
gene id: 697329:RUMAL_RS10570
uniprot id: E6UBF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spermidine/spermine synthase family.
messages: Cell membrane

697329:RUMAL RS09015
gene id: 697329:RUMAL_RS09015
uniprot id: E6UJ06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

697329:RUMAL RS15345
gene id: 697329:RUMAL_RS15345
uniprot id: E6UEA0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

697329:RUMAL RS02200
gene id: 697329:RUMAL_RS02200
uniprot id: E6UF97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

697329:RUMAL RS02270
gene id: 697329:RUMAL_RS02270
uniprot id: E6UFA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

697329:RUMAL RS14590
gene id: 697329:RUMAL_RS14590
uniprot id: E6UIJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS05080
gene id: 697329:RUMAL_RS05080
uniprot id: E6UBX6
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

697329:RUMAL RS02130
gene id: 697329:RUMAL_RS02130
uniprot id: E6UEL9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

697329:RUMAL RS02525
gene id: 697329:RUMAL_RS02525
uniprot id: E6UG20
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

697329:RUMAL RS09545
gene id: 697329:RUMAL_RS09545
uniprot id: E6UAF7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS03340
gene id: 697329:RUMAL_RS03340
uniprot id: E6UHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

697329:RUMAL RS20965
gene id: 697329:RUMAL_RS20965
uniprot id: E6UJA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

697329:RUMAL RS06745
gene id: 697329:RUMAL_RS06745
uniprot id: E6UES7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

697329:RUMAL RS14505
gene id: 697329:RUMAL_RS14505
uniprot id: E6UIH7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

697329:RUMAL RS17640
gene id: 697329:RUMAL_RS17640
uniprot id: E6UJR1
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS15455
gene id: 697329:RUMAL_RS15455
uniprot id: E6UEC2
names: Similarity
messages: Belongs to the transpeptidase family.

697329:RUMAL RS06980
gene id: 697329:RUMAL_RS06980
uniprot id: E6UFI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

697329:RUMAL RS01165
gene id: 697329:RUMAL_RS01165
uniprot id: E6UCZ5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

697329:RUMAL RS00345
gene id: 697329:RUMAL_RS00345
uniprot id: E6UBN7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

697329:RUMAL RS02635
gene id: 697329:RUMAL_RS02635
uniprot id: E6UG41
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS10830
gene id: 697329:RUMAL_RS10830
uniprot id: E6UBK7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

697329:RUMAL RS02410
gene id: 697329:RUMAL_RS02410
uniprot id: E6UFD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS19000
gene id: 697329:RUMAL_RS19000
uniprot id: E6UKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS06415
gene id: 697329:RUMAL_RS06415
uniprot id: E6UDZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

697329:RUMAL RS10730
gene id: 697329:RUMAL_RS10730
uniprot id: E6UBI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

697329:RUMAL RS17565
gene id: 697329:RUMAL_RS17565
uniprot id: E6UJP6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

697329:RUMAL RS19415
gene id: 697329:RUMAL_RS19415
uniprot id: E6UKQ7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS13570
gene id: 697329:RUMAL_RS13570
uniprot id: E6UGM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

697329:RUMAL RS11930
gene id: 697329:RUMAL_RS11930
uniprot id: E6UDF3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

697329:RUMAL RS14965
gene id: 697329:RUMAL_RS14965
uniprot id: E6UJ66
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS04695
gene id: 697329:RUMAL_RS04695
uniprot id: E6UB94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

697329:RUMAL RS05030
gene id: 697329:RUMAL_RS05030
uniprot id: E6UBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

697329:RUMAL RS06640
gene id: 697329:RUMAL_RS06640
uniprot id: E6UEQ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS08225
gene id: 697329:RUMAL_RS08225
uniprot id: E6UHR3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS09485
gene id: 697329:RUMAL_RS09485
uniprot id: E6UAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

697329:RUMAL RS00335
gene id: 697329:RUMAL_RS00335
uniprot id: E6UBN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

697329:RUMAL RS14410
gene id: 697329:RUMAL_RS14410
uniprot id: E6UIF8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

697329:RUMAL RS03400
gene id: 697329:RUMAL_RS03400
uniprot id: E6UHH1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

697329:RUMAL RS11795
gene id: 697329:RUMAL_RS11795
uniprot id: E6UDC6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS13505
gene id: 697329:RUMAL_RS13505
uniprot id: E6UGK9
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

697329:RUMAL RS13400
gene id: 697329:RUMAL_RS13400
uniprot id: E6UGI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS06225
gene id: 697329:RUMAL_RS06225
uniprot id: E6UDV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

697329:RUMAL RS18940
gene id: 697329:RUMAL_RS18940
uniprot id: E6UKG7
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

697329:RUMAL RS10245
gene id: 697329:RUMAL_RS10245
uniprot id: E6UAW8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

697329:RUMAL RS00880
gene id: 697329:RUMAL_RS00880
uniprot id: E6UCE1
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS01065
gene id: 697329:RUMAL_RS01065
uniprot id: E6UCX5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

697329:RUMAL RS05010
gene id: 697329:RUMAL_RS05010
uniprot id: E6UBV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

697329:RUMAL RS01865
gene id: 697329:RUMAL_RS01865
uniprot id: E6UEH2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

697329:RUMAL RS00320
gene id: 697329:RUMAL_RS00320
uniprot id: E6UBN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

697329:RUMAL RS05065
gene id: 697329:RUMAL_RS05065
uniprot id: E6UBX2
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS05895
gene id: 697329:RUMAL_RS05895
uniprot id: E6UD76
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

697329:RUMAL RS19565
gene id: 697329:RUMAL_RS19565
uniprot id: E6UKS9
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS09715
gene id: 697329:RUMAL_RS09715
uniprot id: E6UAI8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

697329:RUMAL RS05150
gene id: 697329:RUMAL_RS05150
uniprot id: E6UBZ0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

697329:RUMAL RS18045
gene id: 697329:RUMAL_RS18045
uniprot id: E6UJY8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

697329:RUMAL RS00745
gene id: 697329:RUMAL_RS00745
uniprot id: E6UCB2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS14270
gene id: 697329:RUMAL_RS14270
uniprot id: E6UHY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

697329:RUMAL RS04780
gene id: 697329:RUMAL_RS04780
uniprot id: E6UBB2
names: Similarity
messages: Belongs to the acylphosphatase family.

697329:RUMAL RS12935
gene id: 697329:RUMAL_RS12935
uniprot id: E6UFN2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

697329:RUMAL RS04810
gene id: 697329:RUMAL_RS04810
uniprot id: E6UBB8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

697329:RUMAL RS10475
gene id: 697329:RUMAL_RS10475
uniprot id: E6UB13
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS11830
gene id: 697329:RUMAL_RS11830
uniprot id: E6UDD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

697329:RUMAL RS13385
gene id: 697329:RUMAL_RS13385
uniprot id: E6UGI5
names: Similarity
messages: Belongs to the NAPRTase family.

697329:RUMAL RS04000
gene id: 697329:RUMAL_RS04000
uniprot id: E6UI63
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

697329:RUMAL RS17875
gene id: 697329:RUMAL_RS17875
uniprot id: E6UJV6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

697329:RUMAL RS13060
gene id: 697329:RUMAL_RS13060
uniprot id: E6UFQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

697329:RUMAL RS12265
gene id: 697329:RUMAL_RS12265
uniprot id: E6UE39
names: Similarity
messages: Belongs to the asp23 family.

697329:RUMAL RS12455
gene id: 697329:RUMAL_RS12455
uniprot id: E6UE76
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

697329:RUMAL RS12560
gene id: 697329:RUMAL_RS12560
uniprot id: E6UEV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

697329:RUMAL RS00600
gene id: 697329:RUMAL_RS00600
uniprot id: E6UBT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

697329:RUMAL RS14815
gene id: 697329:RUMAL_RS14815
uniprot id: E6UJ37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

697329:RUMAL RS06720
gene id: 697329:RUMAL_RS06720
uniprot id: E6UES2
names: Similarity
messages: Belongs to the UPF0751 family.

697329:RUMAL RS01100
gene id: 697329:RUMAL_RS01100
uniprot id: E6UCY2
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

697329:RUMAL RS11385
gene id: 697329:RUMAL_RS11385
uniprot id: E6UCQ6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS14975
gene id: 697329:RUMAL_RS14975
uniprot id: E6UJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

697329:RUMAL RS12015
gene id: 697329:RUMAL_RS12015
uniprot id: E6UDH0
names: Similarity
messages: Belongs to the EamA transporter family.

697329:RUMAL RS06335
gene id: 697329:RUMAL_RS06335
uniprot id: E6UDX7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

697329:RUMAL RS03535
gene id: 697329:RUMAL_RS03535
uniprot id: E6UHJ3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS13585
gene id: 697329:RUMAL_RS13585
uniprot id: E6UGM6
names: Function
names: Subcellular Location Annotation
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Membrane

697329:RUMAL RS15680
gene id: 697329:RUMAL_RS15680
uniprot id: E6UF28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

697329:RUMAL RS15470
gene id: 697329:RUMAL_RS15470
uniprot id: E6UEC5
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS15875
gene id: 697329:RUMAL_RS15875
uniprot id: E6UF68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

697329:RUMAL RS07725
gene id: 697329:RUMAL_RS07725
uniprot id: E6UH25
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

697329:RUMAL RS13450
gene id: 697329:RUMAL_RS13450
uniprot id: E6UGJ8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS10465
gene id: 697329:RUMAL_RS10465
uniprot id: E6UB11
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS19265
gene id: 697329:RUMAL_RS19265
uniprot id: E6UF02
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS10785
gene id: 697329:RUMAL_RS10785
uniprot id: E6UBJ8
names: Similarity
messages: Belongs to the UPF0047 family.

697329:RUMAL RS10145
gene id: 697329:RUMAL_RS10145
uniprot id: E6UAU7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

697329:RUMAL RS20495
gene id: 697329:RUMAL_RS20495
uniprot id: E6UGZ6
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS01490
gene id: 697329:RUMAL_RS01490
uniprot id: E6UDM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

697329:RUMAL RS14430
gene id: 697329:RUMAL_RS14430
uniprot id: E6UIG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

697329:RUMAL RS15025
gene id: 697329:RUMAL_RS15025
uniprot id: E6UJ78
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

697329:RUMAL RS07315
gene id: 697329:RUMAL_RS07315
uniprot id: E6UGB0
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS09570
gene id: 697329:RUMAL_RS09570
uniprot id: E6UAG2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

697329:RUMAL RS14925
gene id: 697329:RUMAL_RS14925
uniprot id: E6UJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

697329:RUMAL RS14640
gene id: 697329:RUMAL_RS14640
uniprot id: E6UIK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS06805
gene id: 697329:RUMAL_RS06805
uniprot id: E6UET9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

697329:RUMAL RS12215
gene id: 697329:RUMAL_RS12215
uniprot id: E6UE29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

697329:RUMAL RS16015
gene id: 697329:RUMAL_RS16015
uniprot id: E6UFU8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

697329:RUMAL RS15325
gene id: 697329:RUMAL_RS15325
uniprot id: E6UE96
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS02215
gene id: 697329:RUMAL_RS02215
uniprot id: E6UFA0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

697329:RUMAL RS18860
gene id: 697329:RUMAL_RS18860
uniprot id: E6UKF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

697329:RUMAL RS13180
gene id: 697329:RUMAL_RS13180
uniprot id: E6UFT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

697329:RUMAL RS12595
gene id: 697329:RUMAL_RS12595
uniprot id: E6UEW7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS12335
gene id: 697329:RUMAL_RS12335
uniprot id: E6UE52
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

697329:RUMAL RS10120
gene id: 697329:RUMAL_RS10120
uniprot id: E6UAR6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

697329:RUMAL RS05770
gene id: 697329:RUMAL_RS05770
uniprot id: E6UD54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

697329:RUMAL RS19070
gene id: 697329:RUMAL_RS19070
uniprot id: E6UKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS09455
gene id: 697329:RUMAL_RS09455
uniprot id: E6UAD8
names: Similarity
messages: Belongs to the TrpF family.

697329:RUMAL RS04495
gene id: 697329:RUMAL_RS04495
uniprot id: E6UAS8
names: Similarity
messages: Belongs to the thioesterase family.

697329:RUMAL RS08780
gene id: 697329:RUMAL_RS08780
uniprot id: E6UIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

697329:RUMAL RS09380
gene id: 697329:RUMAL_RS09380
uniprot id: E6UAC3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

697329:RUMAL RS13190
gene id: 697329:RUMAL_RS13190
uniprot id: E6UFT3
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS12185
gene id: 697329:RUMAL_RS12185
uniprot id: E6UE23
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS06150
gene id: 697329:RUMAL_RS06150
uniprot id: E6UDU0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS05145
gene id: 697329:RUMAL_RS05145
uniprot id: E6UBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS13035
gene id: 697329:RUMAL_RS13035
uniprot id: E6UFQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

697329:RUMAL RS18765
gene id: 697329:RUMAL_RS18765
uniprot id: E6UKD1
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS00250
gene id: 697329:RUMAL_RS00250
uniprot id: E6UB69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

697329:RUMAL RS15825
gene id: 697329:RUMAL_RS15825
uniprot id: E6UF58
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

697329:RUMAL RS10715
gene id: 697329:RUMAL_RS10715
uniprot id: E6UBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

697329:RUMAL RS17510
gene id: 697329:RUMAL_RS17510
uniprot id: E6UF02
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS13105
gene id: 697329:RUMAL_RS13105
uniprot id: E6UFR6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

697329:RUMAL RS17605
gene id: 697329:RUMAL_RS17605
uniprot id: E6UJQ4
names: Similarity
messages: Belongs to the ParB family.

697329:RUMAL RS20180
gene id: 697329:RUMAL_RS20180
uniprot id: E6UL48
names: Similarity
messages: Belongs to the peptidase M18 family.

697329:RUMAL RS12930
gene id: 697329:RUMAL_RS12930
uniprot id: E6UFN1
names: Similarity
messages: Belongs to the SleB family.

697329:RUMAL RS15445
gene id: 697329:RUMAL_RS15445
uniprot id: E6UEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

697329:RUMAL RS11900
gene id: 697329:RUMAL_RS11900
uniprot id: E6UDE7
names: Similarity
messages: Belongs to the DtxR/MntR family.

697329:RUMAL RS05330
gene id: 697329:RUMAL_RS05330
uniprot id: E6UCH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

697329:RUMAL RS16085
gene id: 697329:RUMAL_RS16085
uniprot id: E6UFW1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

697329:RUMAL RS01255
gene id: 697329:RUMAL_RS01255
uniprot id: E6UD11
names: Caution
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

697329:RUMAL RS09065
gene id: 697329:RUMAL_RS09065
uniprot id: E6UJ16
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

697329:RUMAL RS01345
gene id: 697329:RUMAL_RS01345
uniprot id: E6UD30
names: Similarity
messages: Belongs to the GARS family.

697329:RUMAL RS14895
gene id: 697329:RUMAL_RS14895
uniprot id: E6UJ53
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

697329:RUMAL RS12375
gene id: 697329:RUMAL_RS12375
uniprot id: E6UE60
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

697329:RUMAL RS06515
gene id: 697329:RUMAL_RS06515
uniprot id: E6UEN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS19030
gene id: 697329:RUMAL_RS19030
uniprot id: E6UKI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

697329:RUMAL RS14650
gene id: 697329:RUMAL_RS14650
uniprot id: E6UIK6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

697329:RUMAL RS13525
gene id: 697329:RUMAL_RS13525
uniprot id: E6UGL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

697329:RUMAL RS09175
gene id: 697329:RUMAL_RS09175
uniprot id: E6UA82
names: Similarity
messages: Belongs to the YicC/YloC family.

697329:RUMAL RS10070
gene id: 697329:RUMAL_RS10070
uniprot id: E6UAQ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

697329:RUMAL RS01645
gene id: 697329:RUMAL_RS01645
uniprot id: E6UDQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

697329:RUMAL RS09310
gene id: 697329:RUMAL_RS09310
uniprot id: E6UAA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

697329:RUMAL RS02335
gene id: 697329:RUMAL_RS02335
uniprot id: E6UFC3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

697329:RUMAL RS11595
gene id: 697329:RUMAL_RS11595
uniprot id: E6UCU6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

697329:RUMAL RS13120
gene id: 697329:RUMAL_RS13120
uniprot id: E6UFR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

697329:RUMAL RS10750
gene id: 697329:RUMAL_RS10750
uniprot id: E6UBJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

697329:RUMAL RS02810
gene id: 697329:RUMAL_RS02810
uniprot id: E6UG74
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS18315
gene id: 697329:RUMAL_RS18315
uniprot id: E6UK42
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

697329:RUMAL RS08320
gene id: 697329:RUMAL_RS08320
uniprot id: E6UHT4
names: Similarity
messages: Belongs to the NAD synthetase family.

697329:RUMAL RS00095
gene id: 697329:RUMAL_RS00095
uniprot id: E6UB39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

697329:RUMAL RS08825
gene id: 697329:RUMAL_RS08825
uniprot id: E6UIW7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

697329:RUMAL RS09490
gene id: 697329:RUMAL_RS09490
uniprot id: E6UAE5
names: Similarity
messages: Belongs to the asparagine synthetase family.

697329:RUMAL RS01150
gene id: 697329:RUMAL_RS01150
uniprot id: E6UCZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS01920
gene id: 697329:RUMAL_RS01920
uniprot id: E6UEI3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

697329:RUMAL RS07640
gene id: 697329:RUMAL_RS07640
uniprot id: E6UH08
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

697329:RUMAL RS19585
gene id: 697329:RUMAL_RS19585
uniprot id: E6UKT1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

697329:RUMAL RS05035
gene id: 697329:RUMAL_RS05035
uniprot id: E6UBW4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

697329:RUMAL RS02445
gene id: 697329:RUMAL_RS02445
uniprot id: E6UFE5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

697329:RUMAL RS02990
gene id: 697329:RUMAL_RS02990
uniprot id: E6UGV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS08985
gene id: 697329:RUMAL_RS08985
uniprot id: E6UJ00
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

697329:RUMAL RS09290
gene id: 697329:RUMAL_RS09290
uniprot id: E6UAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

697329:RUMAL RS10760
gene id: 697329:RUMAL_RS10760
uniprot id: E6UBJ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS09415
gene id: 697329:RUMAL_RS09415
uniprot id: E6UAD0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

697329:RUMAL RS00380
gene id: 697329:RUMAL_RS00380
uniprot id: E6UBP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

697329:RUMAL RS07855
gene id: 697329:RUMAL_RS07855
uniprot id: E6UH48
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS04435
gene id: 697329:RUMAL_RS04435
uniprot id: E6UIU3
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS09520
gene id: 697329:RUMAL_RS09520
uniprot id: E6UAF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS10350
gene id: 697329:RUMAL_RS10350
uniprot id: E6UAY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

697329:RUMAL RS13540
gene id: 697329:RUMAL_RS13540
uniprot id: E6UGL6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

697329:RUMAL RS12835
gene id: 697329:RUMAL_RS12835
uniprot id: E6UF10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

697329:RUMAL RS00245
gene id: 697329:RUMAL_RS00245
uniprot id: E6UB68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

697329:RUMAL RS13160
gene id: 697329:RUMAL_RS13160
uniprot id: E6UFS7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

697329:RUMAL RS08415
gene id: 697329:RUMAL_RS08415
uniprot id: E6UI91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS15910
gene id: 697329:RUMAL_RS15910
uniprot id: E6UF75
names: Similarity
messages: Belongs to the fabD family.

697329:RUMAL RS01605
gene id: 697329:RUMAL_RS01605
uniprot id: E6UDP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

697329:RUMAL RS09215
gene id: 697329:RUMAL_RS09215
uniprot id: E6UA90
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

697329:RUMAL RS10950
gene id: 697329:RUMAL_RS10950
uniprot id: E6UC25
names: Similarity
messages: Belongs to the ThiD family.

697329:RUMAL RS15620
gene id: 697329:RUMAL_RS15620
uniprot id: E6UEF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

697329:RUMAL RS03100
gene id: 697329:RUMAL_RS03100
uniprot id: E6UGX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS20105
gene id: 697329:RUMAL_RS20105
uniprot id: E6UL33
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

697329:RUMAL RS05445
gene id: 697329:RUMAL_RS05445
uniprot id: E6UCJ4
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS00265
gene id: 697329:RUMAL_RS00265
uniprot id: E6UB72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

697329:RUMAL RS05750
gene id: 697329:RUMAL_RS05750
uniprot id: E6UD50
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

697329:RUMAL RS12385
gene id: 697329:RUMAL_RS12385
uniprot id: E6UE62
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

697329:RUMAL RS07700
gene id: 697329:RUMAL_RS07700
uniprot id: E6UH20
names: Similarity
messages: Belongs to the IMPACT family.

697329:RUMAL RS19645
gene id: 697329:RUMAL_RS19645
uniprot id: E6UKU3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

697329:RUMAL RS10240
gene id: 697329:RUMAL_RS10240
uniprot id: E6UAW7
names: Similarity
messages: Belongs to the SfsA family.

697329:RUMAL RS08635
gene id: 697329:RUMAL_RS08635
uniprot id: E6UID7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

697329:RUMAL RS12875
gene id: 697329:RUMAL_RS12875
uniprot id: E6UFM7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

697329:RUMAL RS00530
gene id: 697329:RUMAL_RS00530
uniprot id: E6UBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

697329:RUMAL RS02820
gene id: 697329:RUMAL_RS02820
uniprot id: E6UG76
names: Similarity
messages: Belongs to the HupF/HypC family.

697329:RUMAL RS01030
gene id: 697329:RUMAL_RS01030
uniprot id: E6UCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

697329:RUMAL RS10790
gene id: 697329:RUMAL_RS10790
uniprot id: E6UBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

697329:RUMAL RS06355
gene id: 697329:RUMAL_RS06355
uniprot id: E6UDY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

697329:RUMAL RS08355
gene id: 697329:RUMAL_RS08355
uniprot id: E6UI79
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

697329:RUMAL RS18745
gene id: 697329:RUMAL_RS18745
uniprot id: E6UKC7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

697329:RUMAL RS20210
gene id: 697329:RUMAL_RS20210
uniprot id: E6UL54
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS00285
gene id: 697329:RUMAL_RS00285
uniprot id: E6UBM5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

697329:RUMAL RS04850
gene id: 697329:RUMAL_RS04850
uniprot id: E6UBC7
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

697329:RUMAL RS12230
gene id: 697329:RUMAL_RS12230
uniprot id: E6UE32
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

697329:RUMAL RS03940
gene id: 697329:RUMAL_RS03940
uniprot id: E6UI51
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

697329:RUMAL RS18790
gene id: 697329:RUMAL_RS18790
uniprot id: E6UKD6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS11020
gene id: 697329:RUMAL_RS11020
uniprot id: E6UC39
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

697329:RUMAL RS02115
gene id: 697329:RUMAL_RS02115
uniprot id: E6UEL6
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

697329:RUMAL RS14790
gene id: 697329:RUMAL_RS14790
uniprot id: E6UJ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

697329:RUMAL RS08310
gene id: 697329:RUMAL_RS08310
uniprot id: E6UHT2
names: Subcellular Location Annotation
messages: Cytoplasm

697329:RUMAL RS18080
gene id: 697329:RUMAL_RS18080
uniprot id: E6UJZ5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

697329:RUMAL RS11970
gene id: 697329:RUMAL_RS11970
uniprot id: E6UDG1
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

697329:RUMAL RS01905
gene id: 697329:RUMAL_RS01905
uniprot id: E6UEI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

697329:RUMAL RS00610
gene id: 697329:RUMAL_RS00610
uniprot id: E6UBT8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS11870
gene id: 697329:RUMAL_RS11870
uniprot id: E6UDE1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

697329:RUMAL RS02080
gene id: 697329:RUMAL_RS02080
uniprot id: E6UEK9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

697329:RUMAL RS01340
gene id: 697329:RUMAL_RS01340
uniprot id: E6UD28
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS08410
gene id: 697329:RUMAL_RS08410
uniprot id: E6UI90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

697329:RUMAL RS14955
gene id: 697329:RUMAL_RS14955
uniprot id: E6UJ64
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

697329:RUMAL RS15515
gene id: 697329:RUMAL_RS15515
uniprot id: E6UED4
names: Similarity
messages: Belongs to the serpin family.

697329:RUMAL RS16235
gene id: 697329:RUMAL_RS16235
uniprot id: E6UFY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

697329:RUMAL RS20070
gene id: 697329:RUMAL_RS20070
uniprot id: E6UL25
names: Similarity
messages: Belongs to the pyruvate kinase family.

697329:RUMAL RS02155
gene id: 697329:RUMAL_RS02155
uniprot id: E6UF93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

697329:RUMAL RS01215
gene id: 697329:RUMAL_RS01215
uniprot id: E6UD03
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

697329:RUMAL RS00715
gene id: 697329:RUMAL_RS00715
uniprot id: E6UCA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

697329:RUMAL RS08385
gene id: 697329:RUMAL_RS08385
uniprot id: E6UI85
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

697329:RUMAL RS08420
gene id: 697329:RUMAL_RS08420
uniprot id: E6UI92
names: Similarity
messages: Belongs to the UPF0237 family.

697329:RUMAL RS05055
gene id: 697329:RUMAL_RS05055
uniprot id: E6UBW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

697329:RUMAL RS09350
gene id: 697329:RUMAL_RS09350
uniprot id: E6UAB7
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS07580
gene id: 697329:RUMAL_RS07580
uniprot id: E6UGF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS12785
gene id: 697329:RUMAL_RS12785
uniprot id: E6UF02
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS15950
gene id: 697329:RUMAL_RS15950
uniprot id: E6UF83
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

697329:RUMAL RS10780
gene id: 697329:RUMAL_RS10780
uniprot id: E6UBJ7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS15460
gene id: 697329:RUMAL_RS15460
uniprot id: E6UEC3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS16230
gene id: 697329:RUMAL_RS16230
uniprot id: E6UFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

697329:RUMAL RS03055
gene id: 697329:RUMAL_RS03055
uniprot id: E6UGW5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS04320
gene id: 697329:RUMAL_RS04320
uniprot id: E6UIR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

697329:RUMAL RS15695
gene id: 697329:RUMAL_RS15695
uniprot id: E6UF31
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

697329:RUMAL RS00005
gene id: 697329:RUMAL_RS00005
uniprot id: E6UB24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

697329:RUMAL RS15595
gene id: 697329:RUMAL_RS15595
uniprot id: E6UEE8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

697329:RUMAL RS15670
gene id: 697329:RUMAL_RS15670
uniprot id: E6UF26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

697329:RUMAL RS01485
gene id: 697329:RUMAL_RS01485
uniprot id: E6UDM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

697329:RUMAL RS10095
gene id: 697329:RUMAL_RS10095
uniprot id: E6UAR1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

697329:RUMAL RS01125
gene id: 697329:RUMAL_RS01125
uniprot id: E6UCY7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

697329:RUMAL RS11170
gene id: 697329:RUMAL_RS11170
uniprot id: E6UC70
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

697329:RUMAL RS19590
gene id: 697329:RUMAL_RS19590
uniprot id: E6UKT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

697329:RUMAL RS09115
gene id: 697329:RUMAL_RS09115
uniprot id: E6UA70
names: Similarity
messages: Belongs to the FBPase class 3 family.

697329:RUMAL RS16660
gene id: 697329:RUMAL_RS16660
uniprot id: E6UGS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

697329:RUMAL RS12200
gene id: 697329:RUMAL_RS12200
uniprot id: E6UE26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

697329:RUMAL RS02535
gene id: 697329:RUMAL_RS02535
uniprot id: E6UG22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

697329:RUMAL RS04460
gene id: 697329:RUMAL_RS04460
uniprot id: E6UAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS08630
gene id: 697329:RUMAL_RS08630
uniprot id: E6UID6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

697329:RUMAL RS02895
gene id: 697329:RUMAL_RS02895
uniprot id: E6UG91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

697329:RUMAL RS11180
gene id: 697329:RUMAL_RS11180
uniprot id: E6UC72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

697329:RUMAL RS10825
gene id: 697329:RUMAL_RS10825
uniprot id: E6UBK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS01295
gene id: 697329:RUMAL_RS01295
uniprot id: E6UD19
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

697329:RUMAL RS15205
gene id: 697329:RUMAL_RS15205
uniprot id: E6UDK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS03030
gene id: 697329:RUMAL_RS03030
uniprot id: E6UGW0
names: Subcellular Location Annotation
messages: Cell membrane

697329:RUMAL RS04675
gene id: 697329:RUMAL_RS04675
uniprot id: E6UB90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS19050
gene id: 697329:RUMAL_RS19050
uniprot id: E6UKI7
names: Similarity
messages: Belongs to the threonine synthase family.

697329:RUMAL RS12565
gene id: 697329:RUMAL_RS12565
uniprot id: E6UEW0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS08265
gene id: 697329:RUMAL_RS08265
uniprot id: E6UHS1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

697329:RUMAL RS02120
gene id: 697329:RUMAL_RS02120
uniprot id: E6UEL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

697329:RUMAL RS02075
gene id: 697329:RUMAL_RS02075
uniprot id: E6UEK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

697329:RUMAL RS01585
gene id: 697329:RUMAL_RS01585
uniprot id: E6UDP4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

697329:RUMAL RS00435
gene id: 697329:RUMAL_RS00435
uniprot id: E6UBQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

697329:RUMAL RS08330
gene id: 697329:RUMAL_RS08330
uniprot id: E6UHT6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

697329:RUMAL RS16665
gene id: 697329:RUMAL_RS16665
uniprot id: E6UGT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

697329:RUMAL RS11980
gene id: 697329:RUMAL_RS11980
uniprot id: E6UDG3
names: Similarity
messages: Belongs to the TelA family.

697329:RUMAL RS15870
gene id: 697329:RUMAL_RS15870
uniprot id: E6UF67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

697329:RUMAL RS06130
gene id: 697329:RUMAL_RS06130
uniprot id: E6UDT7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

697329:RUMAL RS15270
gene id: 697329:RUMAL_RS15270
uniprot id: E6UE85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

697329:RUMAL RS15770
gene id: 697329:RUMAL_RS15770
uniprot id: E6UF46
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

697329:RUMAL RS05185
gene id: 697329:RUMAL_RS05185
uniprot id: E6UBZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS15000
gene id: 697329:RUMAL_RS15000
uniprot id: E6UJ73
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

697329:RUMAL RS01075
gene id: 697329:RUMAL_RS01075
uniprot id: E6UCX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

697329:RUMAL RS09105
gene id: 697329:RUMAL_RS09105
uniprot id: E6UJ24
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS04395
gene id: 697329:RUMAL_RS04395
uniprot id: E6UIT5
names: Similarity
messages: Belongs to the peptidase A8 family.

697329:RUMAL RS04905
gene id: 697329:RUMAL_RS04905
uniprot id: E6UBD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

697329:RUMAL RS19835
gene id: 697329:RUMAL_RS19835
uniprot id: E6UKY1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

697329:RUMAL RS20155
gene id: 697329:RUMAL_RS20155
uniprot id: E6UL43
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

697329:RUMAL RS01595
gene id: 697329:RUMAL_RS01595
uniprot id: E6UDP6
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

697329:RUMAL RS08200
gene id: 697329:RUMAL_RS08200
uniprot id: E6UHQ8
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

697329:RUMAL RS20115
gene id: 697329:RUMAL_RS20115
uniprot id: E6UL35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

697329:RUMAL RS03110
gene id: 697329:RUMAL_RS03110
uniprot id: E6UGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS16095
gene id: 697329:RUMAL_RS16095
uniprot id: E6UFW3
names: Similarity
messages: Belongs to the thioredoxin family.

697329:RUMAL RS00205
gene id: 697329:RUMAL_RS00205
uniprot id: E6UB60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

697329:RUMAL RS02385
gene id: 697329:RUMAL_RS02385
uniprot id: E6UFD3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

697329:RUMAL RS09975
gene id: 697329:RUMAL_RS09975
uniprot id: E6UAN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

697329:RUMAL RS10305
gene id: 697329:RUMAL_RS10305
uniprot id: E6UAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS07805
gene id: 697329:RUMAL_RS07805
uniprot id: E6UH38
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS00605
gene id: 697329:RUMAL_RS00605
uniprot id: E6UBT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

697329:RUMAL RS13990
gene id: 697329:RUMAL_RS13990
uniprot id: E6UHE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

697329:RUMAL RS08725
gene id: 697329:RUMAL_RS08725
uniprot id: E6UIU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS11270
gene id: 697329:RUMAL_RS11270
uniprot id: E6UC90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

697329:RUMAL RS01465
gene id: 697329:RUMAL_RS01465
uniprot id: E6UDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

697329:RUMAL RS15475
gene id: 697329:RUMAL_RS15475
uniprot id: E6UEC6
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS11360
gene id: 697329:RUMAL_RS11360
uniprot id: E6UCQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS08245
gene id: 697329:RUMAL_RS08245
uniprot id: E6UHR7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

697329:RUMAL RS12000
gene id: 697329:RUMAL_RS12000
uniprot id: E6UDG7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

697329:RUMAL RS20050
gene id: 697329:RUMAL_RS20050
uniprot id: E6UL21
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

697329:RUMAL RS05160
gene id: 697329:RUMAL_RS05160
uniprot id: E6UBZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS04535
gene id: 697329:RUMAL_RS04535
uniprot id: E6UAT6
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS04505
gene id: 697329:RUMAL_RS04505
uniprot id: E6UAT0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

697329:RUMAL RS16155
gene id: 697329:RUMAL_RS16155
uniprot id: E6UFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS08455
gene id: 697329:RUMAL_RS08455
uniprot id: E6UI99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS15310
gene id: 697329:RUMAL_RS15310
uniprot id: E6UE93
names: Similarity
messages: Belongs to the ribF family.

697329:RUMAL RS07875
gene id: 697329:RUMAL_RS07875
uniprot id: E6UH52
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS19065
gene id: 697329:RUMAL_RS19065
uniprot id: E6UKJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

697329:RUMAL RS01285
gene id: 697329:RUMAL_RS01285
uniprot id: E6UD17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

697329:RUMAL RS01520
gene id: 697329:RUMAL_RS01520
uniprot id: E6UDN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

697329:RUMAL RS08425
gene id: 697329:RUMAL_RS08425
uniprot id: E6UI93
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

697329:RUMAL RS00090
gene id: 697329:RUMAL_RS00090
uniprot id: E6UB38
names: Similarity
messages: Belongs to the ParB family.

697329:RUMAL RS02540
gene id: 697329:RUMAL_RS02540
uniprot id: E6UG23
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS00360
gene id: 697329:RUMAL_RS00360
uniprot id: E6UBN9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

697329:RUMAL RS15130
gene id: 697329:RUMAL_RS15130
uniprot id: E6UDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

697329:RUMAL RS09735
gene id: 697329:RUMAL_RS09735
uniprot id: E6UAJ2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS11545
gene id: 697329:RUMAL_RS11545
uniprot id: E6UCT5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

697329:RUMAL RS14655
gene id: 697329:RUMAL_RS14655
uniprot id: E6UIK7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS14915
gene id: 697329:RUMAL_RS14915
uniprot id: E6UJ57
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

697329:RUMAL RS00385
gene id: 697329:RUMAL_RS00385
uniprot id: E6UBP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

697329:RUMAL RS16590
gene id: 697329:RUMAL_RS16590
uniprot id: E6UGS4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS10315
gene id: 697329:RUMAL_RS10315
uniprot id: E6UAY2
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS15480
gene id: 697329:RUMAL_RS15480
uniprot id: E6UEC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS00260
gene id: 697329:RUMAL_RS00260
uniprot id: E6UB71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

697329:RUMAL RS08705
gene id: 697329:RUMAL_RS08705
uniprot id: E6UIF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

697329:RUMAL RS09915
gene id: 697329:RUMAL_RS09915
uniprot id: E6UAM6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

697329:RUMAL RS15075
gene id: 697329:RUMAL_RS15075
uniprot id: E6UJ89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS20760
gene id: 697329:RUMAL_RS20760
uniprot id: E6UAI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

697329:RUMAL RS13155
gene id: 697329:RUMAL_RS13155
uniprot id: E6UFS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

697329:RUMAL RS13285
gene id: 697329:RUMAL_RS13285
uniprot id: E6UGG7
names: Similarity
messages: Belongs to the glutamine synthetase family.

697329:RUMAL RS01405
gene id: 697329:RUMAL_RS01405
uniprot id: E6UDK8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

697329:RUMAL RS09500
gene id: 697329:RUMAL_RS09500
uniprot id: E6UAE8
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

697329:RUMAL RS09280
gene id: 697329:RUMAL_RS09280
uniprot id: E6UAA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

697329:RUMAL RS01225
gene id: 697329:RUMAL_RS01225
uniprot id: E6UD05
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

697329:RUMAL RS14295
gene id: 697329:RUMAL_RS14295
uniprot id: E6UHZ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS01005
gene id: 697329:RUMAL_RS01005
uniprot id: E6UCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

697329:RUMAL RS18375
gene id: 697329:RUMAL_RS18375
uniprot id: E6UK54
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS01845
gene id: 697329:RUMAL_RS01845
uniprot id: E6UEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

697329:RUMAL RS08380
gene id: 697329:RUMAL_RS08380
uniprot id: E6UI84
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

697329:RUMAL RS14580
gene id: 697329:RUMAL_RS14580
uniprot id: E6UIJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS05980
gene id: 697329:RUMAL_RS05980
uniprot id: E6UD93
names: Similarity
messages: Belongs to the CapA family.

697329:RUMAL RS15560
gene id: 697329:RUMAL_RS15560
uniprot id: E6UEE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS12235
gene id: 697329:RUMAL_RS12235
uniprot id: E6UE33
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

697329:RUMAL RS02905
gene id: 697329:RUMAL_RS02905
uniprot id: E6UGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

697329:RUMAL RS13975
gene id: 697329:RUMAL_RS13975
uniprot id: E6UHE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

697329:RUMAL RS02755
gene id: 697329:RUMAL_RS02755
uniprot id: E6UG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

697329:RUMAL RS01635
gene id: 697329:RUMAL_RS01635
uniprot id: E6UDQ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS09425
gene id: 697329:RUMAL_RS09425
uniprot id: E6UAD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

697329:RUMAL RS00220
gene id: 697329:RUMAL_RS00220
uniprot id: E6UB63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

697329:RUMAL RS12350
gene id: 697329:RUMAL_RS12350
uniprot id: E6UE55
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

697329:RUMAL RS09370
gene id: 697329:RUMAL_RS09370
uniprot id: E6UAC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS01235
gene id: 697329:RUMAL_RS01235
uniprot id: E6UD07
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS06985
gene id: 697329:RUMAL_RS06985
uniprot id: E6UFI2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

697329:RUMAL RS01720
gene id: 697329:RUMAL_RS01720
uniprot id: E6UDS3
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS08435
gene id: 697329:RUMAL_RS08435
uniprot id: E6UI95
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

697329:RUMAL RS06555
gene id: 697329:RUMAL_RS06555
uniprot id: E6UEN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

697329:RUMAL RS07080
gene id: 697329:RUMAL_RS07080
uniprot id: E6UFK1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

697329:RUMAL RS14180
gene id: 697329:RUMAL_RS14180
uniprot id: E6UHX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

697329:RUMAL RS09755
gene id: 697329:RUMAL_RS09755
uniprot id: E6UAJ6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

697329:RUMAL RS14770
gene id: 697329:RUMAL_RS14770
uniprot id: E6UJ28
names: Function
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.

697329:RUMAL RS18915
gene id: 697329:RUMAL_RS18915
uniprot id: E6UKG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

697329:RUMAL RS11065
gene id: 697329:RUMAL_RS11065
uniprot id: E6UC48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS20045
gene id: 697329:RUMAL_RS20045
uniprot id: E6UL20
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

697329:RUMAL RS05400
gene id: 697329:RUMAL_RS05400
uniprot id: E6UCI5
names: Similarity
messages: Belongs to the CarB family.

697329:RUMAL RS13090
gene id: 697329:RUMAL_RS13090
uniprot id: E6UFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

697329:RUMAL RS15465
gene id: 697329:RUMAL_RS15465
uniprot id: E6UEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

697329:RUMAL RS10520
gene id: 697329:RUMAL_RS10520
uniprot id: E6UB22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

697329:RUMAL RS16070
gene id: 697329:RUMAL_RS16070
uniprot id: E6UFV8
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

697329:RUMAL RS00305
gene id: 697329:RUMAL_RS00305
uniprot id: E6UBM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

697329:RUMAL RS10075
gene id: 697329:RUMAL_RS10075
uniprot id: E6UAQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

697329:RUMAL RS01240
gene id: 697329:RUMAL_RS01240
uniprot id: E6UD08
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS09965
gene id: 697329:RUMAL_RS09965
uniprot id: E6UAN6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

697329:RUMAL RS13085
gene id: 697329:RUMAL_RS13085
uniprot id: E6UFR2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

697329:RUMAL RS11080
gene id: 697329:RUMAL_RS11080
uniprot id: E6UC51
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

697329:RUMAL RS14210
gene id: 697329:RUMAL_RS14210
uniprot id: E6UHX7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

697329:RUMAL RS00240
gene id: 697329:RUMAL_RS00240
uniprot id: E6UB67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

697329:RUMAL RS02185
gene id: 697329:RUMAL_RS02185
uniprot id: E6UF94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

697329:RUMAL RS14145
gene id: 697329:RUMAL_RS14145
uniprot id: E6UHW4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

697329:RUMAL RS10080
gene id: 697329:RUMAL_RS10080
uniprot id: E6UAQ8
names: Subcellular Location Annotation
messages: Cytoplasm

697329:RUMAL RS20890
gene id: 697329:RUMAL_RS20890
uniprot id: E6UHD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

697329:RUMAL RS16940
gene id: 697329:RUMAL_RS16940
uniprot id: E6UJE3
names: Similarity
messages: Belongs to the RecJ family.

697329:RUMAL RS08880
gene id: 697329:RUMAL_RS08880
uniprot id: E6UIX8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

697329:RUMAL RS08490
gene id: 697329:RUMAL_RS08490
uniprot id: E6UIA6
names: Similarity
messages: Belongs to the RecJ family.

697329:RUMAL RS04575
gene id: 697329:RUMAL_RS04575
uniprot id: E6UAU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS13075
gene id: 697329:RUMAL_RS13075
uniprot id: E6UFR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

697329:RUMAL RS02210
gene id: 697329:RUMAL_RS02210
uniprot id: E6UF99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

697329:RUMAL RS10990
gene id: 697329:RUMAL_RS10990
uniprot id: E6UC33
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

697329:RUMAL RS01275
gene id: 697329:RUMAL_RS01275
uniprot id: E6UD15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

697329:RUMAL RS15030
gene id: 697329:RUMAL_RS15030
uniprot id: E6UJ79
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS16125
gene id: 697329:RUMAL_RS16125
uniprot id: E6UFW9
names: Similarity
messages: Belongs to the CapA family.

697329:RUMAL RS18835
gene id: 697329:RUMAL_RS18835
uniprot id: E6UKE5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS00010
gene id: 697329:RUMAL_RS00010
uniprot id: E6UB25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

697329:RUMAL RS18840
gene id: 697329:RUMAL_RS18840
uniprot id: E6UKE6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS15650
gene id: 697329:RUMAL_RS15650
uniprot id: E6UF22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

697329:RUMAL RS14825
gene id: 697329:RUMAL_RS14825
uniprot id: E6UJ39
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

697329:RUMAL RS01070
gene id: 697329:RUMAL_RS01070
uniprot id: E6UCX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

697329:RUMAL RS05990
gene id: 697329:RUMAL_RS05990
uniprot id: E6UD95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

697329:RUMAL RS12600
gene id: 697329:RUMAL_RS12600
uniprot id: E6UEW8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

697329:RUMAL RS07715
gene id: 697329:RUMAL_RS07715
uniprot id: E6UH23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

697329:RUMAL RS01305
gene id: 697329:RUMAL_RS01305
uniprot id: E6UD21
names: Similarity
messages: Belongs to the SAICAR synthetase family.

697329:RUMAL RS15295
gene id: 697329:RUMAL_RS15295
uniprot id: E6UE90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

697329:RUMAL RS02585
gene id: 697329:RUMAL_RS02585
uniprot id: E6UG31
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

697329:RUMAL RS05095
gene id: 697329:RUMAL_RS05095
uniprot id: E6UBX9
names: Similarity
messages: Belongs to the EamA transporter family.

697329:RUMAL RS02285
gene id: 697329:RUMAL_RS02285
uniprot id: E6UFB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

697329:RUMAL RS09945
gene id: 697329:RUMAL_RS09945
uniprot id: E6UAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

697329:RUMAL RS08955
gene id: 697329:RUMAL_RS08955
uniprot id: E6UIZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS08685
gene id: 697329:RUMAL_RS08685
uniprot id: E6UIE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

697329:RUMAL RS18590
gene id: 697329:RUMAL_RS18590
uniprot id: E6UK99
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

697329:RUMAL RS09070
gene id: 697329:RUMAL_RS09070
uniprot id: E6UJ17
names: Similarity
messages: Belongs to the polysaccharide synthase family.

697329:RUMAL RS00965
gene id: 697329:RUMAL_RS00965
uniprot id: E6UCF8
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

697329:RUMAL RS09985
gene id: 697329:RUMAL_RS09985
uniprot id: E6UAP0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

697329:RUMAL RS00630
gene id: 697329:RUMAL_RS00630
uniprot id: E6UBU2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

697329:RUMAL RS12145
gene id: 697329:RUMAL_RS12145
uniprot id: E6UE15
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

697329:RUMAL RS17880
gene id: 697329:RUMAL_RS17880
uniprot id: E6UJV7
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

697329:RUMAL RS15415
gene id: 697329:RUMAL_RS15415
uniprot id: E6UEB4
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

697329:RUMAL RS00210
gene id: 697329:RUMAL_RS00210
uniprot id: E6UB61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

697329:RUMAL RS11235
gene id: 697329:RUMAL_RS11235
uniprot id: E6UC83
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

697329:RUMAL RS15110
gene id: 697329:RUMAL_RS15110
uniprot id: E6UJ96
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

697329:RUMAL RS09285
gene id: 697329:RUMAL_RS09285
uniprot id: E6UAA4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

697329:RUMAL RS14130
gene id: 697329:RUMAL_RS14130
uniprot id: E6UHW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

697329:RUMAL RS01115
gene id: 697329:RUMAL_RS01115
uniprot id: E6UCY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

697329:RUMAL RS14700
gene id: 697329:RUMAL_RS14700
uniprot id: E6UIL6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

697329:RUMAL RS19075
gene id: 697329:RUMAL_RS19075
uniprot id: E6UKJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS09190
gene id: 697329:RUMAL_RS09190
uniprot id: E6UA85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

697329:RUMAL RS04365
gene id: 697329:RUMAL_RS04365
uniprot id: E6UIS9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS03130
gene id: 697329:RUMAL_RS03130
uniprot id: E6UGY0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

697329:RUMAL RS01055
gene id: 697329:RUMAL_RS01055
uniprot id: E6UCX3
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

697329:RUMAL RS01105
gene id: 697329:RUMAL_RS01105
uniprot id: E6UCY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

697329:RUMAL RS19055
gene id: 697329:RUMAL_RS19055
uniprot id: E6UKI8
names: Similarity
messages: Belongs to the UPF0102 family.

697329:RUMAL RS15095
gene id: 697329:RUMAL_RS15095
uniprot id: E6UJ93
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

697329:RUMAL RS05230
gene id: 697329:RUMAL_RS05230
uniprot id: E6UC07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS05985
gene id: 697329:RUMAL_RS05985
uniprot id: E6UD94
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

697329:RUMAL RS03435
gene id: 697329:RUMAL_RS03435
uniprot id: E6UHH7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS00340
gene id: 697329:RUMAL_RS00340
uniprot id: E6UBN6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

697329:RUMAL RS00765
gene id: 697329:RUMAL_RS00765
uniprot id: E6UCB6
names: Similarity
messages: Belongs to the glycosyl hydrolase.

697329:RUMAL RS12095
gene id: 697329:RUMAL_RS12095
uniprot id: E6UE05
names: Similarity
messages: Belongs to the GSP E family.

697329:RUMAL RS14275
gene id: 697329:RUMAL_RS14275
uniprot id: E6UHZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS16775
gene id: 697329:RUMAL_RS16775
uniprot id: E6UJB3
names: Similarity
messages: Belongs to the GSP E family.

697329:RUMAL RS03440
gene id: 697329:RUMAL_RS03440
uniprot id: E6UHH8
names: Similarity
messages: Belongs to the plasmid mobilization pre family.

697329:RUMAL RS15845
gene id: 697329:RUMAL_RS15845
uniprot id: E6UF62
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

697329:RUMAL RS14780
gene id: 697329:RUMAL_RS14780
uniprot id: E6UJ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

697329:RUMAL RS09555
gene id: 697329:RUMAL_RS09555
uniprot id: E6UAF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

697329:RUMAL RS08510
gene id: 697329:RUMAL_RS08510
uniprot id: E6UIB0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

697329:RUMAL RS13175
gene id: 697329:RUMAL_RS13175
uniprot id: E6UFT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

697329:RUMAL RS19665
gene id: 697329:RUMAL_RS19665
uniprot id: E6UKU7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS01085
gene id: 697329:RUMAL_RS01085
uniprot id: E6UCX9
names: Similarity
messages: Belongs to the glutamine synthetase family.

697329:RUMAL RS10755
gene id: 697329:RUMAL_RS10755
uniprot id: E6UBJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

697329:RUMAL RS11975
gene id: 697329:RUMAL_RS11975
uniprot id: E6UDG2
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

697329:RUMAL RS13590
gene id: 697329:RUMAL_RS13590
uniprot id: E6UGM7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

697329:RUMAL RS10115
gene id: 697329:RUMAL_RS10115
uniprot id: E6UAR5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

697329:RUMAL RS01750
gene id: 697329:RUMAL_RS01750
uniprot id: E6UDS9
names: Similarity
messages: Belongs to the class-I fumarase family.

697329:RUMAL RS11320
gene id: 697329:RUMAL_RS11320
uniprot id: E6UCP3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

697329:RUMAL RS01265
gene id: 697329:RUMAL_RS01265
uniprot id: E6UD13
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

697329:RUMAL RS06650
gene id: 697329:RUMAL_RS06650
uniprot id: E6UEQ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

697329:RUMAL RS20135
gene id: 697329:RUMAL_RS20135
uniprot id: E6UL39
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

697329:RUMAL RS13330
gene id: 697329:RUMAL_RS13330
uniprot id: E6UGH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

697329:RUMAL RS12225
gene id: 697329:RUMAL_RS12225
uniprot id: E6UE31
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

697329:RUMAL RS17585
gene id: 697329:RUMAL_RS17585
uniprot id: E6UJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

697329:RUMAL RS06700
gene id: 697329:RUMAL_RS06700
uniprot id: E6UER7
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

697329:RUMAL RS00280
gene id: 697329:RUMAL_RS00280
uniprot id: E6UB75
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

697329:RUMAL RS11810
gene id: 697329:RUMAL_RS11810
uniprot id: E6UDC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

697329:RUMAL RS08980
gene id: 697329:RUMAL_RS08980
uniprot id: E6UIZ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS12105
gene id: 697329:RUMAL_RS12105
uniprot id: E6UE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

697329:RUMAL RS00450
gene id: 697329:RUMAL_RS00450
uniprot id: E6UBQ7
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

697329:RUMAL RS06430
gene id: 697329:RUMAL_RS06430
uniprot id: E6UDZ6
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

697329:RUMAL RS11240
gene id: 697329:RUMAL_RS11240
uniprot id: E6UC84
names: Similarity
messages: Belongs to the LacAB/RpiB family.

697329:RUMAL RS02830
gene id: 697329:RUMAL_RS02830
uniprot id: E6UG78
names: Similarity
messages: Belongs to the HypE family.

697329:RUMAL RS20895
gene id: 697329:RUMAL_RS20895
uniprot id: E6UHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS15885
gene id: 697329:RUMAL_RS15885
uniprot id: E6UF70
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

697329:RUMAL RS08690
gene id: 697329:RUMAL_RS08690
uniprot id: E6UIE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

697329:RUMAL RS00595
gene id: 697329:RUMAL_RS00595
uniprot id: E6UBT5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

697329:RUMAL RS04150
gene id: 697329:RUMAL_RS04150
uniprot id: E6UIP1
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS14060
gene id: 697329:RUMAL_RS14060
uniprot id: E6UHU7
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

697329:RUMAL RS05075
gene id: 697329:RUMAL_RS05075
uniprot id: E6UBX5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

697329:RUMAL RS14610
gene id: 697329:RUMAL_RS14610
uniprot id: E6UIJ7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

697329:RUMAL RS10155
gene id: 697329:RUMAL_RS10155
uniprot id: E6UAV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

697329:RUMAL RS06715
gene id: 697329:RUMAL_RS06715
uniprot id: E6UES0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

697329:RUMAL RS05775
gene id: 697329:RUMAL_RS05775
uniprot id: E6UD55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

697329:RUMAL RS14995
gene id: 697329:RUMAL_RS14995
uniprot id: E6UJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

697329:RUMAL RS05385
gene id: 697329:RUMAL_RS05385
uniprot id: E6UCI2
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS12270
gene id: 697329:RUMAL_RS12270
uniprot id: E6UE40
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

697329:RUMAL RS10930
gene id: 697329:RUMAL_RS10930
uniprot id: E6UBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

697329:RUMAL RS13575
gene id: 697329:RUMAL_RS13575
uniprot id: E6UGM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

697329:RUMAL RS01450
gene id: 697329:RUMAL_RS01450
uniprot id: E6UDL7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

697329:RUMAL RS13970
gene id: 697329:RUMAL_RS13970
uniprot id: E6UHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

697329:RUMAL RS15305
gene id: 697329:RUMAL_RS15305
uniprot id: E6UE92
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

697329:RUMAL RS06880
gene id: 697329:RUMAL_RS06880
uniprot id: E6UFG0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

697329:RUMAL RS01900
gene id: 697329:RUMAL_RS01900
uniprot id: E6UEH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS06240
gene id: 697329:RUMAL_RS06240
uniprot id: E6UDV9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

697329:RUMAL RS15510
gene id: 697329:RUMAL_RS15510
uniprot id: E6UED3
names: Similarity
messages: Belongs to the class-I fumarase family.

697329:RUMAL RS16240
gene id: 697329:RUMAL_RS16240
uniprot id: E6UFZ0
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS10165
gene id: 697329:RUMAL_RS10165
uniprot id: E6UAV2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

697329:RUMAL RS03470
gene id: 697329:RUMAL_RS03470
uniprot id: E6UDT7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

697329:RUMAL RS14810
gene id: 697329:RUMAL_RS14810
uniprot id: E6UJ36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

697329:RUMAL RS01060
gene id: 697329:RUMAL_RS01060
uniprot id: E6UCX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS09775
gene id: 697329:RUMAL_RS09775
uniprot id: E6UAK0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

697329:RUMAL RS13980
gene id: 697329:RUMAL_RS13980
uniprot id: E6UHE1
names: Similarity
messages: Belongs to the CdaR family.

697329:RUMAL RS09950
gene id: 697329:RUMAL_RS09950
uniprot id: E6UAN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS07985
gene id: 697329:RUMAL_RS07985
uniprot id: E6UH74
names: Similarity
messages: Belongs to the UPF0251 family.

697329:RUMAL RS00235
gene id: 697329:RUMAL_RS00235
uniprot id: E6UB66
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

697329:RUMAL RS10485
gene id: 697329:RUMAL_RS10485
uniprot id: E6UB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

697329:RUMAL RS05415
gene id: 697329:RUMAL_RS05415
uniprot id: E6UCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

697329:RUMAL RS19025
gene id: 697329:RUMAL_RS19025
uniprot id: E6UKI1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

697329:RUMAL RS02425
gene id: 697329:RUMAL_RS02425
uniprot id: E6UFE1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

697329:RUMAL RS07635
gene id: 697329:RUMAL_RS07635
uniprot id: E6UH07
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

697329:RUMAL RS02825
gene id: 697329:RUMAL_RS02825
uniprot id: E6UG77
names: Similarity
messages: Belongs to the HypD family.

697329:RUMAL RS20415
gene id: 697329:RUMAL_RS20415
uniprot id: E6UBU0
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS05605
gene id: 697329:RUMAL_RS05605
uniprot id: E6UCM3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS03065
gene id: 697329:RUMAL_RS03065
uniprot id: E6UGW7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

697329:RUMAL RS09160
gene id: 697329:RUMAL_RS09160
uniprot id: E6UA79
names: Similarity
messages: Belongs to the UPF0178 family.

697329:RUMAL RS00225
gene id: 697329:RUMAL_RS00225
uniprot id: E6UB64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

697329:RUMAL RS14635
gene id: 697329:RUMAL_RS14635
uniprot id: E6UIK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS12245
gene id: 697329:RUMAL_RS12245
uniprot id: E6UE35
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS17430
gene id: 697329:RUMAL_RS17430
uniprot id: E6UJM3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

697329:RUMAL RS15315
gene id: 697329:RUMAL_RS15315
uniprot id: E6UE94
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS02625
gene id: 697329:RUMAL_RS02625
uniprot id: E6UG39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

697329:RUMAL RS08040
gene id: 697329:RUMAL_RS08040
uniprot id: E6UHM8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

697329:RUMAL RS06420
gene id: 697329:RUMAL_RS06420
uniprot id: E6UDZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

697329:RUMAL RS15990
gene id: 697329:RUMAL_RS15990
uniprot id: E6UF90
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

697329:RUMAL RS10105
gene id: 697329:RUMAL_RS10105
uniprot id: E6UAR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

697329:RUMAL RS06350
gene id: 697329:RUMAL_RS06350
uniprot id: E6UDY0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

697329:RUMAL RS00230
gene id: 697329:RUMAL_RS00230
uniprot id: E6UB65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

697329:RUMAL RS11195
gene id: 697329:RUMAL_RS11195
uniprot id: P49985
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Sequence (AAA73925.1) highly divergent from genome sequence. It could originate from another bacterial species.

697329:RUMAL RS08115
gene id: 697329:RUMAL_RS08115
uniprot id: E6UHP2
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS15940
gene id: 697329:RUMAL_RS15940
uniprot id: E6UF81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

697329:RUMAL RS02780
gene id: 697329:RUMAL_RS02780
uniprot id: E6UG68
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

697329:RUMAL RS04710
gene id: 697329:RUMAL_RS04710
uniprot id: E6UB97
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS14250
gene id: 697329:RUMAL_RS14250
uniprot id: E6UHY5
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS10505
gene id: 697329:RUMAL_RS10505
uniprot id: E6UB19
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

697329:RUMAL RS08450
gene id: 697329:RUMAL_RS08450
uniprot id: E6UI98
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

697329:RUMAL RS05460
gene id: 697329:RUMAL_RS05460
uniprot id: E6UCJ7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

697329:RUMAL RS01840
gene id: 697329:RUMAL_RS01840
uniprot id: E6UEG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

697329:RUMAL RS00290
gene id: 697329:RUMAL_RS00290
uniprot id: E6UBM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

697329:RUMAL RS00750
gene id: 697329:RUMAL_RS00750
uniprot id: E6UCB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

697329:RUMAL RS05955
gene id: 697329:RUMAL_RS05955
uniprot id: E6UD88
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS05170
gene id: 697329:RUMAL_RS05170
uniprot id: E6UBZ5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

697329:RUMAL RS09955
gene id: 697329:RUMAL_RS09955
uniprot id: E6UAN4
names: Similarity
messages: Belongs to the TlyA family.

697329:RUMAL RS13530
gene id: 697329:RUMAL_RS13530
uniprot id: E6UGL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

697329:RUMAL RS16650
gene id: 697329:RUMAL_RS16650
uniprot id: E6UGS7
names: Similarity
messages: Belongs to the peptidase S51 family.

697329:RUMAL RS05275
gene id: 697329:RUMAL_RS05275
uniprot id: E6UC17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS07430
gene id: 697329:RUMAL_RS07430
uniprot id: E6UGC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

697329:RUMAL RS07710
gene id: 697329:RUMAL_RS07710
uniprot id: E6UH22
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

697329:RUMAL RS11820
gene id: 697329:RUMAL_RS11820
uniprot id: E6UDD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

697329:RUMAL RS00510
gene id: 697329:RUMAL_RS00510
uniprot id: E6UBR9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Both RaMP1 (Rumal_0852) and RaMP2 catalyze the phosphorolysis of a beta-1,4-mannosidic linkage at the non-reducing end of a substrate, but acceptor specificities are clearly different.
messages: Catalyzes the phosphorolysis of beta-1,4-mannooligosaccharides to mannose 1-phosphate (Man1P) and shorter mannooligosaccharides. Can also catalyze the phosphorolysis of 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc), but shows higher activity toward longer mannooligosaccharides. Involved in a mannan catabolic pathway which feeds into glycolysis.
messages: Homohexamer in solution.

697329:RUMAL RS06345
gene id: 697329:RUMAL_RS06345
uniprot id: E6UDX9
names: Similarity
messages: Belongs to the peptidase S8 family.

697329:RUMAL RS00905
gene id: 697329:RUMAL_RS00905
uniprot id: E6UCE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

697329:RUMAL RS02000
gene id: 697329:RUMAL_RS02000
uniprot id: E6UEJ3
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS06455
gene id: 697329:RUMAL_RS06455
uniprot id: E6UE01
names: Similarity
messages: Belongs to the AlaDH/PNT family.

697329:RUMAL RS05355
gene id: 697329:RUMAL_RS05355
uniprot id: E6UCH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

697329:RUMAL RS12205
gene id: 697329:RUMAL_RS12205
uniprot id: E6UE27
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

697329:RUMAL RS15585
gene id: 697329:RUMAL_RS15585
uniprot id: E6UEE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

697329:RUMAL RS02235
gene id: 697329:RUMAL_RS02235
uniprot id: E6UFA3
names: Similarity
messages: Belongs to the EamA transporter family.

697329:RUMAL RS16640
gene id: 697329:RUMAL_RS16640
uniprot id: E6UGS5
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS09100
gene id: 697329:RUMAL_RS09100
uniprot id: E6UJ23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

697329:RUMAL RS00120
gene id: 697329:RUMAL_RS00120
uniprot id: E6UB44
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS10290
gene id: 697329:RUMAL_RS10290
uniprot id: E6UAX6
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS02295
gene id: 697329:RUMAL_RS02295
uniprot id: E6UFB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

697329:RUMAL RS08105
gene id: 697329:RUMAL_RS08105
uniprot id: E6UHP0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

697329:RUMAL RS14555
gene id: 697329:RUMAL_RS14555
uniprot id: E6UII6
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

697329:RUMAL RS00270
gene id: 697329:RUMAL_RS00270
uniprot id: E6UB73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

697329:RUMAL RS18850
gene id: 697329:RUMAL_RS18850
uniprot id: E6UKE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

697329:RUMAL RS09090
gene id: 697329:RUMAL_RS09090
uniprot id: E6UJ21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

697329:RUMAL RS01505
gene id: 697329:RUMAL_RS01505
uniprot id: E6UDM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

697329:RUMAL RS19550
gene id: 697329:RUMAL_RS19550
uniprot id: E6UKS6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

697329:RUMAL RS04870
gene id: 697329:RUMAL_RS04870
uniprot id: E6UBD1
names: Similarity
messages: Belongs to the ArsC family.

697329:RUMAL RS20060
gene id: 697329:RUMAL_RS20060
uniprot id: E6UL23
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

697329:RUMAL RS00255
gene id: 697329:RUMAL_RS00255
uniprot id: E6UB70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

697329:RUMAL RS05765
gene id: 697329:RUMAL_RS05765
uniprot id: E6UD53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

697329:RUMAL RS13475
gene id: 697329:RUMAL_RS13475
uniprot id: E6UGK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS05005
gene id: 697329:RUMAL_RS05005
uniprot id: E6UBV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

697329:RUMAL RS14775
gene id: 697329:RUMAL_RS14775
uniprot id: E6UJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

697329:RUMAL RS17355
gene id: 697329:RUMAL_RS17355
uniprot id: E6UJL1
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

697329:RUMAL RS16005
gene id: 697329:RUMAL_RS16005
uniprot id: E6UFU6
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS13600
gene id: 697329:RUMAL_RS13600
uniprot id: E6UGM8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS09080
gene id: 697329:RUMAL_RS09080
uniprot id: E6UJ19
names: Similarity
messages: Belongs to the ArsC family.

697329:RUMAL RS20035
gene id: 697329:RUMAL_RS20035
uniprot id: E6UL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

697329:RUMAL RS09195
gene id: 697329:RUMAL_RS09195
uniprot id: E6UA86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

697329:RUMAL RS01475
gene id: 697329:RUMAL_RS01475
uniprot id: E6UDM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

697329:RUMAL RS05245
gene id: 697329:RUMAL_RS05245
uniprot id: E6UC10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

697329:RUMAL RS15725
gene id: 697329:RUMAL_RS15725
uniprot id: E6UF37
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

697329:RUMAL RS01455
gene id: 697329:RUMAL_RS01455
uniprot id: E6UDL8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

697329:RUMAL RS18875
gene id: 697329:RUMAL_RS18875
uniprot id: E6UKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

697329:RUMAL RS18960
gene id: 697329:RUMAL_RS18960
uniprot id: E6UKG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS19860
gene id: 697329:RUMAL_RS19860
uniprot id: E6UKY5
names: Similarity
messages: Belongs to the HsdR family.

697329:RUMAL RS08010
gene id: 697329:RUMAL_RS08010
uniprot id: E6UHM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

697329:RUMAL RS15805
gene id: 697329:RUMAL_RS15805
uniprot id: E6UF54
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

697329:RUMAL RS09510
gene id: 697329:RUMAL_RS09510
uniprot id: E6UAF0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

697329:RUMAL RS02070
gene id: 697329:RUMAL_RS02070
uniprot id: E6UEK7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

697329:RUMAL RS10800
gene id: 697329:RUMAL_RS10800
uniprot id: E6UBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

697329:RUMAL RS13065
gene id: 697329:RUMAL_RS13065
uniprot id: E6UFQ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

697329:RUMAL RS08255
gene id: 697329:RUMAL_RS08255
uniprot id: E6UHR9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

697329:RUMAL RS17350
gene id: 697329:RUMAL_RS17350
uniprot id: E6UJL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

697329:RUMAL RS00295
gene id: 697329:RUMAL_RS00295
uniprot id: E6UBM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

697329:RUMAL RS15055
gene id: 697329:RUMAL_RS15055
uniprot id: E6UJ84
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

697329:RUMAL RS15705
gene id: 697329:RUMAL_RS15705
uniprot id: E6UF33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

697329:RUMAL RS15430
gene id: 697329:RUMAL_RS15430
uniprot id: E6UEB7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS13425
gene id: 697329:RUMAL_RS13425
uniprot id: E6UGJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS13195
gene id: 697329:RUMAL_RS13195
uniprot id: E6UFT4
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS04955
gene id: 697329:RUMAL_RS04955
uniprot id: E6UBE9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS06815
gene id: 697329:RUMAL_RS06815
uniprot id: E6UEU1
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS20585
gene id: 697329:RUMAL_RS20585
uniprot id: E6UB84
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

697329:RUMAL RS09435
gene id: 697329:RUMAL_RS09435
uniprot id: E6UAD4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

697329:RUMAL RS03155
gene id: 697329:RUMAL_RS03155
uniprot id: E6UGY3
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS15185
gene id: 697329:RUMAL_RS15185
uniprot id: E6UDJ8
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

697329:RUMAL RS13440
gene id: 697329:RUMAL_RS13440
uniprot id: E6UGJ6
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS08270
gene id: 697329:RUMAL_RS08270
uniprot id: E6UHS2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

697329:RUMAL RS13100
gene id: 697329:RUMAL_RS13100
uniprot id: E6UFR5
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS11160
gene id: 697329:RUMAL_RS11160
uniprot id: E6UC68
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

697329:RUMAL RS06040
gene id: 697329:RUMAL_RS06040
uniprot id: E6UDA5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

697329:RUMAL RS12615
gene id: 697329:RUMAL_RS12615
uniprot id: E6UEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

697329:RUMAL RS18575
gene id: 697329:RUMAL_RS18575
uniprot id: E6UK96
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

697329:RUMAL RS09200
gene id: 697329:RUMAL_RS09200
uniprot id: E6UA87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

697329:RUMAL RS08560
gene id: 697329:RUMAL_RS08560
uniprot id: E6UIC0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

697329:RUMAL RS04935
gene id: 697329:RUMAL_RS04935
uniprot id: E6UBE5
names: Similarity
messages: Belongs to the manganese catalase family.

697329:RUMAL RS00515
gene id: 697329:RUMAL_RS00515
uniprot id: E6UBS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

697329:RUMAL RS13795
gene id: 697329:RUMAL_RS13795
uniprot id: E6UHA6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS13985
gene id: 697329:RUMAL_RS13985
uniprot id: E6UHE2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

697329:RUMAL RS15490
gene id: 697329:RUMAL_RS15490
uniprot id: E6UEC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS04735
gene id: 697329:RUMAL_RS04735
uniprot id: E6UBA2
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS10845
gene id: 697329:RUMAL_RS10845
uniprot id: E6UBL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

697329:RUMAL RS09245
gene id: 697329:RUMAL_RS09245
uniprot id: E6UA96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS19675
gene id: 697329:RUMAL_RS19675
uniprot id: E6UKU9
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

697329:RUMAL RS08140
gene id: 697329:RUMAL_RS08140
uniprot id: E6UHP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

697329:RUMAL RS19850
gene id: 697329:RUMAL_RS19850
uniprot id: E6UKY3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

697329:RUMAL RS15765
gene id: 697329:RUMAL_RS15765
uniprot id: E6UF45
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS10635
gene id: 697329:RUMAL_RS10635
uniprot id: E6UBG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

697329:RUMAL RS05235
gene id: 697329:RUMAL_RS05235
uniprot id: E6UC08
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

697329:RUMAL RS19255
gene id: 697329:RUMAL_RS19255
uniprot id: E6UKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

697329:RUMAL RS01220
gene id: 697329:RUMAL_RS01220
uniprot id: E6UD04
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

697329:RUMAL RS07060
gene id: 697329:RUMAL_RS07060
uniprot id: E6UFJ6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

697329:RUMAL RS08710
gene id: 697329:RUMAL_RS08710
uniprot id: E6UIF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

697329:RUMAL RS12620
gene id: 697329:RUMAL_RS12620
uniprot id: E6UEX2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

697329:RUMAL RS07405
gene id: 697329:RUMAL_RS07405
uniprot id: E6UGC3
names: Similarity
messages: Belongs to the peptidase S8 family.

697329:RUMAL RS04155
gene id: 697329:RUMAL_RS04155
uniprot id: E6UIP2
names: Subcellular Location Annotation
messages: Membrane

697329:RUMAL RS13095
gene id: 697329:RUMAL_RS13095
uniprot id: E6UFR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

697329:RUMAL RS02100
gene id: 697329:RUMAL_RS02100
uniprot id: E6UEL3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

697329:RUMAL RS05905
gene id: 697329:RUMAL_RS05905
uniprot id: E6UD78
names: Subcellular Location Annotation
messages: Membrane