694427:PALPR RS08460
gene id: 694427:PALPR_RS08460
uniprot id: E4T543
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

694427:PALPR RS02560
gene id: 694427:PALPR_RS02560
uniprot id: E4T1T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

694427:PALPR RS13440
gene id: 694427:PALPR_RS13440
uniprot id: E4T7Y3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS02730
gene id: 694427:PALPR_RS02730
uniprot id: E4T1W7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS08850
gene id: 694427:PALPR_RS08850
uniprot id: E4T5B6
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14080
gene id: 694427:PALPR_RS14080
uniprot id: E4T8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

694427:PALPR RS06900
gene id: 694427:PALPR_RS06900
uniprot id: E4T482
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

694427:PALPR RS03170
gene id: 694427:PALPR_RS03170
uniprot id: E4T257
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

694427:PALPR RS11525
gene id: 694427:PALPR_RS11525
uniprot id: E4T6U8
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

694427:PALPR RS03625
gene id: 694427:PALPR_RS03625
uniprot id: E4T2E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

694427:PALPR RS09430
gene id: 694427:PALPR_RS09430
uniprot id: E4T5N0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

694427:PALPR RS03295
gene id: 694427:PALPR_RS03295
uniprot id: E4T283
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

694427:PALPR RS04220
gene id: 694427:PALPR_RS04220
uniprot id: E4T2R2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

694427:PALPR RS14100
gene id: 694427:PALPR_RS14100
uniprot id: E4T8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

694427:PALPR RS15480
gene id: 694427:PALPR_RS15480
uniprot id: E4T6N2
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS03095
gene id: 694427:PALPR_RS03095
uniprot id: E4T240
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

694427:PALPR RS03100
gene id: 694427:PALPR_RS03100
uniprot id: E4T241
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS03340
gene id: 694427:PALPR_RS03340
uniprot id: E4T291
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS02915
gene id: 694427:PALPR_RS02915
uniprot id: E4T206
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

694427:PALPR RS04520
gene id: 694427:PALPR_RS04520
uniprot id: E4T2X1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

694427:PALPR RS15380
gene id: 694427:PALPR_RS15380
uniprot id: E4T4X6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS13685
gene id: 694427:PALPR_RS13685
uniprot id: E4T833
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

694427:PALPR RS00545
gene id: 694427:PALPR_RS00545
uniprot id: E4T081
names: Similarity
messages: Belongs to the peptidase S9A family.

694427:PALPR RS06400
gene id: 694427:PALPR_RS06400
uniprot id: E4T3Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

694427:PALPR RS02650
gene id: 694427:PALPR_RS02650
uniprot id: E4T1V0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

694427:PALPR RS12230
gene id: 694427:PALPR_RS12230
uniprot id: E4T783
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

694427:PALPR RS04750
gene id: 694427:PALPR_RS04750
uniprot id: E4T315
names: Similarity
messages: Belongs to the polysaccharide synthase family.

694427:PALPR RS12235
gene id: 694427:PALPR_RS12235
uniprot id: E4T784
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

694427:PALPR RS09160
gene id: 694427:PALPR_RS09160
uniprot id: E4T5H7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

694427:PALPR RS07655
gene id: 694427:PALPR_RS07655
uniprot id: E4T4N4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS01450
gene id: 694427:PALPR_RS01450
uniprot id: E4T173
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

694427:PALPR RS08175
gene id: 694427:PALPR_RS08175
uniprot id: E4T4Y6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

694427:PALPR RS02975
gene id: 694427:PALPR_RS02975
uniprot id: E4T218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

694427:PALPR RS06850
gene id: 694427:PALPR_RS06850
uniprot id: E4T471
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

694427:PALPR RS06490
gene id: 694427:PALPR_RS06490
uniprot id: E4T403
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

694427:PALPR RS08455
gene id: 694427:PALPR_RS08455
uniprot id: E4T542
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS04965
gene id: 694427:PALPR_RS04965
uniprot id: E4T359
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

694427:PALPR RS11680
gene id: 694427:PALPR_RS11680
uniprot id: E4T6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS05820
gene id: 694427:PALPR_RS05820
uniprot id: E4T3M2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

694427:PALPR RS02045
gene id: 694427:PALPR_RS02045
uniprot id: E4T1H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

694427:PALPR RS14145
gene id: 694427:PALPR_RS14145
uniprot id: E4T8C7
names: Similarity
messages: Belongs to the ArsC family.

694427:PALPR RS10155
gene id: 694427:PALPR_RS10155
uniprot id: E4T619
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

694427:PALPR RS05045
gene id: 694427:PALPR_RS05045
uniprot id: E4T373
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS01195
gene id: 694427:PALPR_RS01195
uniprot id: E4T117
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

694427:PALPR RS04240
gene id: 694427:PALPR_RS04240
uniprot id: E4T2R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

694427:PALPR RS10285
gene id: 694427:PALPR_RS10285
uniprot id: E4T645
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

694427:PALPR RS01210
gene id: 694427:PALPR_RS01210
uniprot id: E4T120
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

694427:PALPR RS12250
gene id: 694427:PALPR_RS12250
uniprot id: E4T787
names: Subcellular Location Annotation
messages: Cytoplasm

694427:PALPR RS00285
gene id: 694427:PALPR_RS00285
uniprot id: E4T0U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

694427:PALPR RS10705
gene id: 694427:PALPR_RS10705
uniprot id: E4T6D3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS06995
gene id: 694427:PALPR_RS06995
uniprot id: E4T4A0
names: Similarity
messages: Belongs to the peptidase C40 family.

694427:PALPR RS04435
gene id: 694427:PALPR_RS04435
uniprot id: E4T2V4
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS12800
gene id: 694427:PALPR_RS12800
uniprot id: E4T7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

694427:PALPR RS07550
gene id: 694427:PALPR_RS07550
uniprot id: E4T4L2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

694427:PALPR RS03085
gene id: 694427:PALPR_RS03085
uniprot id: E4T238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

694427:PALPR RS09710
gene id: 694427:PALPR_RS09710
uniprot id: E4T5T2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

694427:PALPR RS15175
gene id: 694427:PALPR_RS15175
uniprot id: E4T8R9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

694427:PALPR RS08760
gene id: 694427:PALPR_RS08760
uniprot id: E4T597
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

694427:PALPR RS11945
gene id: 694427:PALPR_RS11945
uniprot id: E4T730
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

694427:PALPR RS09265
gene id: 694427:PALPR_RS09265
uniprot id: E4T5J7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

694427:PALPR RS14285
gene id: 694427:PALPR_RS14285
uniprot id: E4T8F5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

694427:PALPR RS03980
gene id: 694427:PALPR_RS03980
uniprot id: E4T2L7
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS12320
gene id: 694427:PALPR_RS12320
uniprot id: E4T7A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

694427:PALPR RS06205
gene id: 694427:PALPR_RS06205
uniprot id: E4T3U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

694427:PALPR RS00710
gene id: 694427:PALPR_RS00710
uniprot id: E4T0E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

694427:PALPR RS03925
gene id: 694427:PALPR_RS03925
uniprot id: E4T2K5
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

694427:PALPR RS12325
gene id: 694427:PALPR_RS12325
uniprot id: E4T7A3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

694427:PALPR RS14420
gene id: 694427:PALPR_RS14420
uniprot id: E4T8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

694427:PALPR RS12385
gene id: 694427:PALPR_RS12385
uniprot id: E4T7B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

694427:PALPR RS11160
gene id: 694427:PALPR_RS11160
uniprot id: E4T6M7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

694427:PALPR RS10000
gene id: 694427:PALPR_RS10000
uniprot id: E4T5Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

694427:PALPR RS14320
gene id: 694427:PALPR_RS14320
uniprot id: E4T8G2
names: Similarity
messages: Belongs to the universal stress protein A family.

694427:PALPR RS11215
gene id: 694427:PALPR_RS11215
uniprot id: E4T6N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

694427:PALPR RS05455
gene id: 694427:PALPR_RS05455
uniprot id: E4T3E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

694427:PALPR RS02550
gene id: 694427:PALPR_RS02550
uniprot id: E4T1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS15375
gene id: 694427:PALPR_RS15375
uniprot id: E4T4X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

694427:PALPR RS00150
gene id: 694427:PALPR_RS00150
uniprot id: E4T0R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

694427:PALPR RS07620
gene id: 694427:PALPR_RS07620
uniprot id: E4T4M6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS10745
gene id: 694427:PALPR_RS10745
uniprot id: E4T6E1
names: Similarity
messages: Belongs to the peptidase S49 family.

694427:PALPR RS04250
gene id: 694427:PALPR_RS04250
uniprot id: E4T2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS09080
gene id: 694427:PALPR_RS09080
uniprot id: E4T5G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

694427:PALPR RS07515
gene id: 694427:PALPR_RS07515
uniprot id: E4T4K5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS08865
gene id: 694427:PALPR_RS08865
uniprot id: E4T5B9
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

694427:PALPR RS08485
gene id: 694427:PALPR_RS08485
uniprot id: E4T548
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

694427:PALPR RS03645
gene id: 694427:PALPR_RS03645
uniprot id: E4T2F3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

694427:PALPR RS06045
gene id: 694427:PALPR_RS06045
uniprot id: E4T3R7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

694427:PALPR RS13870
gene id: 694427:PALPR_RS13870
uniprot id: E4T872
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS05475
gene id: 694427:PALPR_RS05475
uniprot id: E4T3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS01755
gene id: 694427:PALPR_RS01755
uniprot id: E4T1C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

694427:PALPR RS14075
gene id: 694427:PALPR_RS14075
uniprot id: E4T8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

694427:PALPR RS13640
gene id: 694427:PALPR_RS13640
uniprot id: E4T824
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

694427:PALPR RS06085
gene id: 694427:PALPR_RS06085
uniprot id: E4T3S6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS05825
gene id: 694427:PALPR_RS05825
uniprot id: E4T3M3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

694427:PALPR RS06635
gene id: 694427:PALPR_RS06635
uniprot id: E4T430
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

694427:PALPR RS04065
gene id: 694427:PALPR_RS04065
uniprot id: E4T2N4
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS09055
gene id: 694427:PALPR_RS09055
uniprot id: E4T5F7
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

694427:PALPR RS04140
gene id: 694427:PALPR_RS04140
uniprot id: E4T2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

694427:PALPR RS12635
gene id: 694427:PALPR_RS12635
uniprot id: E4T7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS13700
gene id: 694427:PALPR_RS13700
uniprot id: E4T836
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

694427:PALPR RS12065
gene id: 694427:PALPR_RS12065
uniprot id: E4T752
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS13270
gene id: 694427:PALPR_RS13270
uniprot id: E4T7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

694427:PALPR RS07395
gene id: 694427:PALPR_RS07395
uniprot id: E4T4I1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

694427:PALPR RS12090
gene id: 694427:PALPR_RS12090
uniprot id: E4T757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

694427:PALPR RS13500
gene id: 694427:PALPR_RS13500
uniprot id: E4T7Z6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

694427:PALPR RS15155
gene id: 694427:PALPR_RS15155
uniprot id: E4T8R5
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

694427:PALPR RS04900
gene id: 694427:PALPR_RS04900
uniprot id: E4T345
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

694427:PALPR RS03380
gene id: 694427:PALPR_RS03380
uniprot id: E4T299
names: Similarity
messages: Belongs to the fabD family.

694427:PALPR RS06100
gene id: 694427:PALPR_RS06100
uniprot id: E4T3S9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

694427:PALPR RS03630
gene id: 694427:PALPR_RS03630
uniprot id: E4T2E9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

694427:PALPR RS05335
gene id: 694427:PALPR_RS05335
uniprot id: E4T3C7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

694427:PALPR RS02725
gene id: 694427:PALPR_RS02725
uniprot id: E4T1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

694427:PALPR RS10425
gene id: 694427:PALPR_RS10425
uniprot id: E4T673
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

694427:PALPR RS08140
gene id: 694427:PALPR_RS08140
uniprot id: E4T4X9
names: Similarity
messages: Belongs to the UPF0311 family.

694427:PALPR RS12605
gene id: 694427:PALPR_RS12605
uniprot id: E4T7G1
names: Similarity
messages: Belongs to the peptidase M16 family.

694427:PALPR RS11020
gene id: 694427:PALPR_RS11020
uniprot id: E4T6J8
names: Similarity
messages: Belongs to the UPF0758 family.

694427:PALPR RS09640
gene id: 694427:PALPR_RS09640
uniprot id: E4T5R8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

694427:PALPR RS12905
gene id: 694427:PALPR_RS12905
uniprot id: E4T7M2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

694427:PALPR RS11440
gene id: 694427:PALPR_RS11440
uniprot id: E4T6T1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS03750
gene id: 694427:PALPR_RS03750
uniprot id: E4T2H1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

694427:PALPR RS11780
gene id: 694427:PALPR_RS11780
uniprot id: E4T6Z9
names: Similarity
messages: Belongs to the SUI1 family.

694427:PALPR RS10385
gene id: 694427:PALPR_RS10385
uniprot id: E4T665
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

694427:PALPR RS15025
gene id: 694427:PALPR_RS15025
uniprot id: E4T8N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

694427:PALPR RS07105
gene id: 694427:PALPR_RS07105
uniprot id: E4T4C1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

694427:PALPR RS01030
gene id: 694427:PALPR_RS01030
uniprot id: E4T0Y4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

694427:PALPR RS08785
gene id: 694427:PALPR_RS08785
uniprot id: E4T5A3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS03950
gene id: 694427:PALPR_RS03950
uniprot id: E4T2L0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS06370
gene id: 694427:PALPR_RS06370
uniprot id: E4T3X9
names: Similarity
messages: Belongs to the type IA topoisomerase family.

694427:PALPR RS09950
gene id: 694427:PALPR_RS09950
uniprot id: E4T5X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

694427:PALPR RS07660
gene id: 694427:PALPR_RS07660
uniprot id: E4T4N5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

694427:PALPR RS01880
gene id: 694427:PALPR_RS01880
uniprot id: E4T1E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

694427:PALPR RS13275
gene id: 694427:PALPR_RS13275
uniprot id: E4T7V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

694427:PALPR RS13510
gene id: 694427:PALPR_RS13510
uniprot id: E4T7Z8
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS08705
gene id: 694427:PALPR_RS08705
uniprot id: E4T586
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS12340
gene id: 694427:PALPR_RS12340
uniprot id: E4T7A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

694427:PALPR RS10530
gene id: 694427:PALPR_RS10530
uniprot id: E4T696
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

694427:PALPR RS04355
gene id: 694427:PALPR_RS04355
uniprot id: E4T2T9
names: Similarity
messages: Belongs to the SecB family.

694427:PALPR RS00165
gene id: 694427:PALPR_RS00165
uniprot id: E4T0R7
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS09300
gene id: 694427:PALPR_RS09300
uniprot id: E4T5K4
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS15150
gene id: 694427:PALPR_RS15150
uniprot id: E4T8R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS04925
gene id: 694427:PALPR_RS04925
uniprot id: E4T350
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

694427:PALPR RS13405
gene id: 694427:PALPR_RS13405
uniprot id: E4T7X6
names: Similarity
messages: Belongs to the CapA family.

694427:PALPR RS02785
gene id: 694427:PALPR_RS02785
uniprot id: E4T1X9
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

694427:PALPR RS02955
gene id: 694427:PALPR_RS02955
uniprot id: E4T214
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06610
gene id: 694427:PALPR_RS06610
uniprot id: E4T425
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

694427:PALPR RS01530
gene id: 694427:PALPR_RS01530
uniprot id: E4T190
names: Similarity
messages: Belongs to the OprB family.

694427:PALPR RS14350
gene id: 694427:PALPR_RS14350
uniprot id: E4T8G8
names: Similarity
messages: Belongs to the UPF0111 family.

694427:PALPR RS01060
gene id: 694427:PALPR_RS01060
uniprot id: E4T0Z0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

694427:PALPR RS01510
gene id: 694427:PALPR_RS01510
uniprot id: E4T185
names: Similarity
messages: Belongs to the DEAD box helicase family.

694427:PALPR RS06650
gene id: 694427:PALPR_RS06650
uniprot id: E4T433
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

694427:PALPR RS07950
gene id: 694427:PALPR_RS07950
uniprot id: E4T4U2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

694427:PALPR RS00980
gene id: 694427:PALPR_RS00980
uniprot id: E4T0X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

694427:PALPR RS11720
gene id: 694427:PALPR_RS11720
uniprot id: E4T6Y8
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14590
gene id: 694427:PALPR_RS14590
uniprot id: E4T0J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

694427:PALPR RS05075
gene id: 694427:PALPR_RS05075
uniprot id: E4T378
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS01890
gene id: 694427:PALPR_RS01890
uniprot id: E4T1E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

694427:PALPR RS00495
gene id: 694427:PALPR_RS00495
uniprot id: E4T072
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

694427:PALPR RS16025
gene id: 694427:PALPR_RS16025
uniprot id: E4T0W0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS11725
gene id: 694427:PALPR_RS11725
uniprot id: E4T6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

694427:PALPR RS02525
gene id: 694427:PALPR_RS02525
uniprot id: E4T1S4
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS13675
gene id: 694427:PALPR_RS13675
uniprot id: E4T831
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS08015
gene id: 694427:PALPR_RS08015
uniprot id: E4T4V5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

694427:PALPR RS12375
gene id: 694427:PALPR_RS12375
uniprot id: E4T7B3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

694427:PALPR RS12335
gene id: 694427:PALPR_RS12335
uniprot id: E4T7A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

694427:PALPR RS07930
gene id: 694427:PALPR_RS07930
uniprot id: E4T4T8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

694427:PALPR RS07110
gene id: 694427:PALPR_RS07110
uniprot id: E4T4C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

694427:PALPR RS13045
gene id: 694427:PALPR_RS13045
uniprot id: E4T7P9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

694427:PALPR RS14605
gene id: 694427:PALPR_RS14605
uniprot id: E4T0K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

694427:PALPR RS12015
gene id: 694427:PALPR_RS12015
uniprot id: E4T743
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

694427:PALPR RS08925
gene id: 694427:PALPR_RS08925
uniprot id: E4T5D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

694427:PALPR RS12885
gene id: 694427:PALPR_RS12885
uniprot id: E4T7L8
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

694427:PALPR RS10005
gene id: 694427:PALPR_RS10005
uniprot id: E4T5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

694427:PALPR RS14850
gene id: 694427:PALPR_RS14850
uniprot id: E4T0P8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

694427:PALPR RS06005
gene id: 694427:PALPR_RS06005
uniprot id: E4T3Q7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

694427:PALPR RS00295
gene id: 694427:PALPR_RS00295
uniprot id: E4T0U5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS05275
gene id: 694427:PALPR_RS05275
uniprot id: E4T3B7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

694427:PALPR RS13605
gene id: 694427:PALPR_RS13605
uniprot id: E4T817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

694427:PALPR RS02490
gene id: 694427:PALPR_RS02490
uniprot id: E4T1R7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

694427:PALPR RS10735
gene id: 694427:PALPR_RS10735
uniprot id: E4T6D9
names: Similarity
messages: Belongs to the peptidase M13 family.

694427:PALPR RS01985
gene id: 694427:PALPR_RS01985
uniprot id: E4T1G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

694427:PALPR RS10940
gene id: 694427:PALPR_RS10940
uniprot id: E4T6I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

694427:PALPR RS02665
gene id: 694427:PALPR_RS02665
uniprot id: E4T1V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

694427:PALPR RS09425
gene id: 694427:PALPR_RS09425
uniprot id: E4T5M9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

694427:PALPR RS12440
gene id: 694427:PALPR_RS12440
uniprot id: E4T7C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

694427:PALPR RS11400
gene id: 694427:PALPR_RS11400
uniprot id: E4T6S5
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

694427:PALPR RS03420
gene id: 694427:PALPR_RS03420
uniprot id: E4T2A7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

694427:PALPR RS08395
gene id: 694427:PALPR_RS08395
uniprot id: E4T531
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

694427:PALPR RS07530
gene id: 694427:PALPR_RS07530
uniprot id: E4T4K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

694427:PALPR RS08280
gene id: 694427:PALPR_RS08280
uniprot id: E4T507
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

694427:PALPR RS04205
gene id: 694427:PALPR_RS04205
uniprot id: E4T2Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

694427:PALPR RS07750
gene id: 694427:PALPR_RS07750
uniprot id: E4T4Q4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

694427:PALPR RS01500
gene id: 694427:PALPR_RS01500
uniprot id: E4T183
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

694427:PALPR RS08585
gene id: 694427:PALPR_RS08585
uniprot id: E4T563
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

694427:PALPR RS00430
gene id: 694427:PALPR_RS00430
uniprot id: E4T058
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS08240
gene id: 694427:PALPR_RS08240
uniprot id: E4T4Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS10725
gene id: 694427:PALPR_RS10725
uniprot id: E4T6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

694427:PALPR RS10315
gene id: 694427:PALPR_RS10315
uniprot id: E4T651
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

694427:PALPR RS09155
gene id: 694427:PALPR_RS09155
uniprot id: E4T5H6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

694427:PALPR RS14475
gene id: 694427:PALPR_RS14475
uniprot id: E4T8J4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

694427:PALPR RS10780
gene id: 694427:PALPR_RS10780
uniprot id: E4T6E8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

694427:PALPR RS00830
gene id: 694427:PALPR_RS00830
uniprot id: E4T0G5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

694427:PALPR RS08555
gene id: 694427:PALPR_RS08555
uniprot id: E4T561
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

694427:PALPR RS06420
gene id: 694427:PALPR_RS06420
uniprot id: E4T3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

694427:PALPR RS07160
gene id: 694427:PALPR_RS07160
uniprot id: E4T4D2
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

694427:PALPR RS13840
gene id: 694427:PALPR_RS13840
uniprot id: E4T864
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

694427:PALPR RS07145
gene id: 694427:PALPR_RS07145
uniprot id: E4T4C9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

694427:PALPR RS08605
gene id: 694427:PALPR_RS08605
uniprot id: E4T566
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

694427:PALPR RS04905
gene id: 694427:PALPR_RS04905
uniprot id: E4T346
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

694427:PALPR RS00680
gene id: 694427:PALPR_RS00680
uniprot id: E4T0D9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS02385
gene id: 694427:PALPR_RS02385
uniprot id: E4T1P7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

694427:PALPR RS00795
gene id: 694427:PALPR_RS00795
uniprot id: E4T0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

694427:PALPR RS00640
gene id: 694427:PALPR_RS00640
uniprot id: E4T0D1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

694427:PALPR RS06765
gene id: 694427:PALPR_RS06765
uniprot id: E4T455
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

694427:PALPR RS14545
gene id: 694427:PALPR_RS14545
uniprot id: E4T8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

694427:PALPR RS10455
gene id: 694427:PALPR_RS10455
uniprot id: E4T679
names: Similarity
messages: Belongs to the peptidase M13 family.

694427:PALPR RS10935
gene id: 694427:PALPR_RS10935
uniprot id: E4T6I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

694427:PALPR RS05850
gene id: 694427:PALPR_RS05850
uniprot id: E4T3M9
names: Similarity
messages: Belongs to the CinA family.

694427:PALPR RS13385
gene id: 694427:PALPR_RS13385
uniprot id: E4T7X3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

694427:PALPR RS00230
gene id: 694427:PALPR_RS00230
uniprot id: E4T0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

694427:PALPR RS07325
gene id: 694427:PALPR_RS07325
uniprot id: E4T4G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

694427:PALPR RS00800
gene id: 694427:PALPR_RS00800
uniprot id: E4T0G4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

694427:PALPR RS07080
gene id: 694427:PALPR_RS07080
uniprot id: E4T4B6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

694427:PALPR RS15475
gene id: 694427:PALPR_RS15475
uniprot id: E4T6J4
names: Similarity
messages: Belongs to the peptidase C40 family.

694427:PALPR RS05280
gene id: 694427:PALPR_RS05280
uniprot id: E4T3B8
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS03020
gene id: 694427:PALPR_RS03020
uniprot id: E4T226
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

694427:PALPR RS05830
gene id: 694427:PALPR_RS05830
uniprot id: E4T3M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

694427:PALPR RS01615
gene id: 694427:PALPR_RS01615
uniprot id: E4T0A1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

694427:PALPR RS13860
gene id: 694427:PALPR_RS13860
uniprot id: E4T869
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

694427:PALPR RS05570
gene id: 694427:PALPR_RS05570
uniprot id: E4T3H2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

694427:PALPR RS14220
gene id: 694427:PALPR_RS14220
uniprot id: E4T8E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

694427:PALPR RS00360
gene id: 694427:PALPR_RS00360
uniprot id: E4T0V8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS01255
gene id: 694427:PALPR_RS01255
uniprot id: E4T129
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

694427:PALPR RS00455
gene id: 694427:PALPR_RS00455
uniprot id: E4T063
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS12200
gene id: 694427:PALPR_RS12200
uniprot id: E4T777
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

694427:PALPR RS12125
gene id: 694427:PALPR_RS12125
uniprot id: E4T764
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

694427:PALPR RS07685
gene id: 694427:PALPR_RS07685
uniprot id: E4T4P0
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS10925
gene id: 694427:PALPR_RS10925
uniprot id: E4T6H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

694427:PALPR RS11675
gene id: 694427:PALPR_RS11675
uniprot id: E4T6X9
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS12310
gene id: 694427:PALPR_RS12310
uniprot id: E4T7A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

694427:PALPR RS12070
gene id: 694427:PALPR_RS12070
uniprot id: E4T753
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS04215
gene id: 694427:PALPR_RS04215
uniprot id: E4T2R1
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS13830
gene id: 694427:PALPR_RS13830
uniprot id: E4T862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

694427:PALPR RS08955
gene id: 694427:PALPR_RS08955
uniprot id: E4T5D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

694427:PALPR RS00760
gene id: 694427:PALPR_RS00760
uniprot id: E4T0F5
names: Similarity
messages: Belongs to the UPF0246 family.

694427:PALPR RS03905
gene id: 694427:PALPR_RS03905
uniprot id: E4T2K1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS03445
gene id: 694427:PALPR_RS03445
uniprot id: E4T2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

694427:PALPR RS14415
gene id: 694427:PALPR_RS14415
uniprot id: E4T8I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

694427:PALPR RS14235
gene id: 694427:PALPR_RS14235
uniprot id: E4T8E5
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06155
gene id: 694427:PALPR_RS06155
uniprot id: E4T3T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

694427:PALPR RS02335
gene id: 694427:PALPR_RS02335
uniprot id: E4T1N7
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS11995
gene id: 694427:PALPR_RS11995
uniprot id: E4T739
names: Similarity
messages: Belongs to the peptidase M16 family.

694427:PALPR RS09970
gene id: 694427:PALPR_RS09970
uniprot id: E4T5Y3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS10895
gene id: 694427:PALPR_RS10895
uniprot id: E4T6H2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS00395
gene id: 694427:PALPR_RS00395
uniprot id: E4T0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS12585
gene id: 694427:PALPR_RS12585
uniprot id: E4T7F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS03560
gene id: 694427:PALPR_RS03560
uniprot id: E4T2D5
names: Subcellular Location Annotation
messages: Secreted

694427:PALPR RS00310
gene id: 694427:PALPR_RS00310
uniprot id: E4T0V0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

694427:PALPR RS00920
gene id: 694427:PALPR_RS00920
uniprot id: E4T0I2
names: Activity Regulation
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CRISPR-associated endoribonuclease Cas13a family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. Unlike many single-component effectors, this CRISPR-Cas system targets RNA (PubMed:28475872). CRISPR clusters are transcribed from pre-CRISPR RNA (crRNA) and processed into crRNA by this protein (PubMed:28475872). Cleaves linear target ssRNA in a pre-crRNA-dependent fashion, preferentially before U residues (PubMed:28475872). Binding a viable target RNA target activates this protein for non-specific RNA degradation in vitro (called collateral RNA degradation), which is fairly sensitive as it requires picomolar levels of viable target RNA (PubMed:28475872).
messages: Part of a type VI-A uridine-prefering CRISPR-Cas system.
messages: Pre-crRNA processing is metal independent, while crRNA-guided target RNA cleavage is dependent on divalent metal.
messages: Target RNA acts as an activator for non-specific ssRNA degradation (PubMed:28475872).
messages: The target ssRNase active sites are probably within the 2 HEPN-like folds, and the 2 folds interact in vivo.

694427:PALPR RS06565
gene id: 694427:PALPR_RS06565
uniprot id: E4T416
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

694427:PALPR RS10330
gene id: 694427:PALPR_RS10330
uniprot id: E4T654
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS13090
gene id: 694427:PALPR_RS13090
uniprot id: E4T7Q8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

694427:PALPR RS14425
gene id: 694427:PALPR_RS14425
uniprot id: E4T8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

694427:PALPR RS08005
gene id: 694427:PALPR_RS08005
uniprot id: E4T4V3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

694427:PALPR RS06955
gene id: 694427:PALPR_RS06955
uniprot id: E4T492
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

694427:PALPR RS11210
gene id: 694427:PALPR_RS11210
uniprot id: E4T6N7
names: Similarity
messages: Belongs to the pyruvate kinase family.

694427:PALPR RS08510
gene id: 694427:PALPR_RS08510
uniprot id: E4T553
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

694427:PALPR RS02095
gene id: 694427:PALPR_RS02095
uniprot id: E4T1I9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS07665
gene id: 694427:PALPR_RS07665
uniprot id: E4T4N6
names: Similarity
messages: Belongs to the isochorismate synthase family.

694427:PALPR RS09400
gene id: 694427:PALPR_RS09400
uniprot id: E4T5M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

694427:PALPR RS05905
gene id: 694427:PALPR_RS05905
uniprot id: E4T3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

694427:PALPR RS00675
gene id: 694427:PALPR_RS00675
uniprot id: E4T0D8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

694427:PALPR RS06035
gene id: 694427:PALPR_RS06035
uniprot id: E4T3R5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

694427:PALPR RS10355
gene id: 694427:PALPR_RS10355
uniprot id: E4T659
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

694427:PALPR RS07690
gene id: 694427:PALPR_RS07690
uniprot id: E4T4P1
names: Similarity
messages: Belongs to the peptidase C69 family.

694427:PALPR RS01590
gene id: 694427:PALPR_RS01590
uniprot id: E4T096
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

694427:PALPR RS06815
gene id: 694427:PALPR_RS06815
uniprot id: E4T465
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

694427:PALPR RS09085
gene id: 694427:PALPR_RS09085
uniprot id: E4T5G1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

694427:PALPR RS05965
gene id: 694427:PALPR_RS05965
uniprot id: E4T3P8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

694427:PALPR RS07535
gene id: 694427:PALPR_RS07535
uniprot id: E4T4K9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

694427:PALPR RS07995
gene id: 694427:PALPR_RS07995
uniprot id: E4T4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS12240
gene id: 694427:PALPR_RS12240
uniprot id: E4T785
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

694427:PALPR RS08265
gene id: 694427:PALPR_RS08265
uniprot id: E4T504
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

694427:PALPR RS09395
gene id: 694427:PALPR_RS09395
uniprot id: E4T5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS11065
gene id: 694427:PALPR_RS11065
uniprot id: E4T6K8
names: Similarity
messages: Belongs to the peptidase C1 family.

694427:PALPR RS03620
gene id: 694427:PALPR_RS03620
uniprot id: E4T2E7
names: Similarity
messages: Belongs to the CapA family.

694427:PALPR RS00300
gene id: 694427:PALPR_RS00300
uniprot id: E4T0U8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

694427:PALPR RS05960
gene id: 694427:PALPR_RS05960
uniprot id: E4T3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

694427:PALPR RS03910
gene id: 694427:PALPR_RS03910
uniprot id: E4T2K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

694427:PALPR RS07260
gene id: 694427:PALPR_RS07260
uniprot id: E4T4F3
names: Similarity
messages: Belongs to the ParB family.

694427:PALPR RS06385
gene id: 694427:PALPR_RS06385
uniprot id: E4T3Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

694427:PALPR RS06805
gene id: 694427:PALPR_RS06805
uniprot id: E4T463
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

694427:PALPR RS02050
gene id: 694427:PALPR_RS02050
uniprot id: E4T1H9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

694427:PALPR RS07305
gene id: 694427:PALPR_RS07305
uniprot id: E4T4G3
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

694427:PALPR RS14040
gene id: 694427:PALPR_RS14040
uniprot id: E4T8A6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

694427:PALPR RS12455
gene id: 694427:PALPR_RS12455
uniprot id: E4T7D0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

694427:PALPR RS08815
gene id: 694427:PALPR_RS08815
uniprot id: E4T5A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

694427:PALPR RS02115
gene id: 694427:PALPR_RS02115
uniprot id: E4T1J3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

694427:PALPR RS13690
gene id: 694427:PALPR_RS13690
uniprot id: E4T834
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS00845
gene id: 694427:PALPR_RS00845
uniprot id: E4T0G8
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

694427:PALPR RS06075
gene id: 694427:PALPR_RS06075
uniprot id: E4T3S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

694427:PALPR RS12360
gene id: 694427:PALPR_RS12360
uniprot id: E4T7B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

694427:PALPR RS07445
gene id: 694427:PALPR_RS07445
uniprot id: E4T4J3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

694427:PALPR RS02680
gene id: 694427:PALPR_RS02680
uniprot id: E4T1V7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

694427:PALPR RS14095
gene id: 694427:PALPR_RS14095
uniprot id: E4T8B6
names: Similarity
messages: Belongs to the peptidase S8 family.

694427:PALPR RS03150
gene id: 694427:PALPR_RS03150
uniprot id: E4T252
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

694427:PALPR RS07770
gene id: 694427:PALPR_RS07770
uniprot id: E4T4Q7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS03055
gene id: 694427:PALPR_RS03055
uniprot id: E4T232
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

694427:PALPR RS10130
gene id: 694427:PALPR_RS10130
uniprot id: E4T614
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

694427:PALPR RS14520
gene id: 694427:PALPR_RS14520
uniprot id: E4T8K2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS12365
gene id: 694427:PALPR_RS12365
uniprot id: E4T7B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

694427:PALPR RS13725
gene id: 694427:PALPR_RS13725
uniprot id: E4T841
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

694427:PALPR RS08135
gene id: 694427:PALPR_RS08135
uniprot id: E4T4X8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS14355
gene id: 694427:PALPR_RS14355
uniprot id: E4T8G9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

694427:PALPR RS07140
gene id: 694427:PALPR_RS07140
uniprot id: E4T4C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

694427:PALPR RS06025
gene id: 694427:PALPR_RS06025
uniprot id: E4T3R1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

694427:PALPR RS10035
gene id: 694427:PALPR_RS10035
uniprot id: E4T5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

694427:PALPR RS05305
gene id: 694427:PALPR_RS05305
uniprot id: E4T3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

694427:PALPR RS01205
gene id: 694427:PALPR_RS01205
uniprot id: E4T119
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

694427:PALPR RS05200
gene id: 694427:PALPR_RS05200
uniprot id: E4T3A2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

694427:PALPR RS04035
gene id: 694427:PALPR_RS04035
uniprot id: E4T2M6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS14270
gene id: 694427:PALPR_RS14270
uniprot id: E4T8F2
names: Similarity
messages: Belongs to the RutC family.

694427:PALPR RS03745
gene id: 694427:PALPR_RS03745
uniprot id: E4T2H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

694427:PALPR RS01875
gene id: 694427:PALPR_RS01875
uniprot id: E4T1E4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

694427:PALPR RS06020
gene id: 694427:PALPR_RS06020
uniprot id: E4T3R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS02355
gene id: 694427:PALPR_RS02355
uniprot id: E4T1P1
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS07565
gene id: 694427:PALPR_RS07565
uniprot id: E4T4L5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

694427:PALPR RS03845
gene id: 694427:PALPR_RS03845
uniprot id: E4T2J0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

694427:PALPR RS14600
gene id: 694427:PALPR_RS14600
uniprot id: E4T0J9
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06685
gene id: 694427:PALPR_RS06685
uniprot id: E4T439
names: Similarity
messages: Belongs to the peptidase M24B family.

694427:PALPR RS00965
gene id: 694427:PALPR_RS00965
uniprot id: E4T0X1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

694427:PALPR RS00875
gene id: 694427:PALPR_RS00875
uniprot id: E4T0H3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS01790
gene id: 694427:PALPR_RS01790
uniprot id: E4T1C7
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06275
gene id: 694427:PALPR_RS06275
uniprot id: E4T3W0
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

694427:PALPR RS00035
gene id: 694427:PALPR_RS00035
uniprot id: E4T0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

694427:PALPR RS08405
gene id: 694427:PALPR_RS08405
uniprot id: E4T533
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

694427:PALPR RS14230
gene id: 694427:PALPR_RS14230
uniprot id: E4T8E4
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS02040
gene id: 694427:PALPR_RS02040
uniprot id: E4T1H7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

694427:PALPR RS03360
gene id: 694427:PALPR_RS03360
uniprot id: E4T295
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

694427:PALPR RS04235
gene id: 694427:PALPR_RS04235
uniprot id: E4T2R5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

694427:PALPR RS04600
gene id: 694427:PALPR_RS04600
uniprot id: E4T2Y8
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

694427:PALPR RS03375
gene id: 694427:PALPR_RS03375
uniprot id: E4T298
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

694427:PALPR RS01640
gene id: 694427:PALPR_RS01640
uniprot id: E4T0A6
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS13845
gene id: 694427:PALPR_RS13845
uniprot id: E4T865
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

694427:PALPR RS12640
gene id: 694427:PALPR_RS12640
uniprot id: E4T7G8
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS08595
gene id: 694427:PALPR_RS08595
uniprot id: E4T564
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

694427:PALPR RS10010
gene id: 694427:PALPR_RS10010
uniprot id: E4T5Z0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS06860
gene id: 694427:PALPR_RS06860
uniprot id: E4T473
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

694427:PALPR RS10955
gene id: 694427:PALPR_RS10955
uniprot id: E4T6I4
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

694427:PALPR RS10450
gene id: 694427:PALPR_RS10450
uniprot id: E4T678
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

694427:PALPR RS00895
gene id: 694427:PALPR_RS00895
uniprot id: E4T0H7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

694427:PALPR RS00025
gene id: 694427:PALPR_RS00025
uniprot id: E4T0B1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

694427:PALPR RS10995
gene id: 694427:PALPR_RS10995
uniprot id: E4T6J2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

694427:PALPR RS06770
gene id: 694427:PALPR_RS06770
uniprot id: E4T456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

694427:PALPR RS14435
gene id: 694427:PALPR_RS14435
uniprot id: E4T8I6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

694427:PALPR RS04025
gene id: 694427:PALPR_RS04025
uniprot id: E4T2M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

694427:PALPR RS02750
gene id: 694427:PALPR_RS02750
uniprot id: E4T1X1
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS02780
gene id: 694427:PALPR_RS02780
uniprot id: E4T1X8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

694427:PALPR RS08640
gene id: 694427:PALPR_RS08640
uniprot id: E4T573
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

694427:PALPR RS02480
gene id: 694427:PALPR_RS02480
uniprot id: E4T1R5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

694427:PALPR RS14115
gene id: 694427:PALPR_RS14115
uniprot id: E4T8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

694427:PALPR RS09135
gene id: 694427:PALPR_RS09135
uniprot id: E4T5H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS10310
gene id: 694427:PALPR_RS10310
uniprot id: E4T650
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

694427:PALPR RS11695
gene id: 694427:PALPR_RS11695
uniprot id: E4T6Y3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

694427:PALPR RS06380
gene id: 694427:PALPR_RS06380
uniprot id: E4T3Y1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS11690
gene id: 694427:PALPR_RS11690
uniprot id: E4T6Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

694427:PALPR RS12560
gene id: 694427:PALPR_RS12560
uniprot id: E4T7F1
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS06375
gene id: 694427:PALPR_RS06375
uniprot id: E4T3Y0
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

694427:PALPR RS02475
gene id: 694427:PALPR_RS02475
uniprot id: E4T1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS11340
gene id: 694427:PALPR_RS11340
uniprot id: E4T6R3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

694427:PALPR RS12810
gene id: 694427:PALPR_RS12810
uniprot id: E4T7K3
names: Similarity
messages: Belongs to the CobH/CbiC family.

694427:PALPR RS15445
gene id: 694427:PALPR_RS15445
uniprot id: E4T687
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

694427:PALPR RS07330
gene id: 694427:PALPR_RS07330
uniprot id: E4T4G8
names: Similarity
messages: Belongs to the OprB family.

694427:PALPR RS02325
gene id: 694427:PALPR_RS02325
uniprot id: E4T1N5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

694427:PALPR RS04500
gene id: 694427:PALPR_RS04500
uniprot id: E4T2W7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS03025
gene id: 694427:PALPR_RS03025
uniprot id: E4T227
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

694427:PALPR RS11960
gene id: 694427:PALPR_RS11960
uniprot id: E4T733
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

694427:PALPR RS01250
gene id: 694427:PALPR_RS01250
uniprot id: E4T128
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

694427:PALPR RS05345
gene id: 694427:PALPR_RS05345
uniprot id: E4T3C9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

694427:PALPR RS10715
gene id: 694427:PALPR_RS10715
uniprot id: E4T6D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

694427:PALPR RS11360
gene id: 694427:PALPR_RS11360
uniprot id: E4T6R7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

694427:PALPR RS14995
gene id: 694427:PALPR_RS14995
uniprot id: E4T8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS10695
gene id: 694427:PALPR_RS10695
uniprot id: E4T6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

694427:PALPR RS00435
gene id: 694427:PALPR_RS00435
uniprot id: E4T059
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS01170
gene id: 694427:PALPR_RS01170
uniprot id: E4T112
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS05895
gene id: 694427:PALPR_RS05895
uniprot id: E4T3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

694427:PALPR RS01315
gene id: 694427:PALPR_RS01315
uniprot id: E4T143
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS03005
gene id: 694427:PALPR_RS03005
uniprot id: E4T223
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

694427:PALPR RS11705
gene id: 694427:PALPR_RS11705
uniprot id: E4T6Y5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

694427:PALPR RS05865
gene id: 694427:PALPR_RS05865
uniprot id: E4T3N2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

694427:PALPR RS11930
gene id: 694427:PALPR_RS11930
uniprot id: E4T727
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

694427:PALPR RS03015
gene id: 694427:PALPR_RS03015
uniprot id: E4T225
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

694427:PALPR RS01610
gene id: 694427:PALPR_RS01610
uniprot id: E4T0A0
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS10570
gene id: 694427:PALPR_RS10570
uniprot id: E4T6A4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

694427:PALPR RS00340
gene id: 694427:PALPR_RS00340
uniprot id: E4T0V4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

694427:PALPR RS02790
gene id: 694427:PALPR_RS02790
uniprot id: E4T1Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS13825
gene id: 694427:PALPR_RS13825
uniprot id: E4T861
names: Similarity
messages: Belongs to the aldose epimerase family.

694427:PALPR RS06330
gene id: 694427:PALPR_RS06330
uniprot id: E4T3X1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

694427:PALPR RS14830
gene id: 694427:PALPR_RS14830
uniprot id: E4T0P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

694427:PALPR RS06455
gene id: 694427:PALPR_RS06455
uniprot id: E4T3Z6
names: Similarity
messages: Belongs to the UPF0045 family.

694427:PALPR RS06545
gene id: 694427:PALPR_RS06545
uniprot id: E4T412
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS12405
gene id: 694427:PALPR_RS12405
uniprot id: E4T7C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

694427:PALPR RS08390
gene id: 694427:PALPR_RS08390
uniprot id: E4T530
names: Similarity
messages: Belongs to the LOG family.

694427:PALPR RS01605
gene id: 694427:PALPR_RS01605
uniprot id: E4T099
names: Similarity
messages: Belongs to the pirin family.

694427:PALPR RS14670
gene id: 694427:PALPR_RS14670
uniprot id: E4T0L3
names: Similarity
messages: Belongs to the peptidase S24 family.

694427:PALPR RS14965
gene id: 694427:PALPR_RS14965
uniprot id: E4T8M7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

694427:PALPR RS02160
gene id: 694427:PALPR_RS02160
uniprot id: E4T1K3
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS02545
gene id: 694427:PALPR_RS02545
uniprot id: E4T1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

694427:PALPR RS11670
gene id: 694427:PALPR_RS11670
uniprot id: E4T6X8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS13920
gene id: 694427:PALPR_RS13920
uniprot id: E4T882
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

694427:PALPR RS00215
gene id: 694427:PALPR_RS00215
uniprot id: E4T0S7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

694427:PALPR RS04380
gene id: 694427:PALPR_RS04380
uniprot id: E4T2U4
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06405
gene id: 694427:PALPR_RS06405
uniprot id: E4T3Y6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

694427:PALPR RS11740
gene id: 694427:PALPR_RS11740
uniprot id: E4T6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

694427:PALPR RS08870
gene id: 694427:PALPR_RS08870
uniprot id: E4T5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS13585
gene id: 694427:PALPR_RS13585
uniprot id: E4T813
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS09140
gene id: 694427:PALPR_RS09140
uniprot id: E4T5H3
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

694427:PALPR RS14165
gene id: 694427:PALPR_RS14165
uniprot id: E4T8D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

694427:PALPR RS07240
gene id: 694427:PALPR_RS07240
uniprot id: E4T4E8
names: Similarity
messages: Belongs to the Skp family.

694427:PALPR RS10750
gene id: 694427:PALPR_RS10750
uniprot id: E4T6E2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

694427:PALPR RS11005
gene id: 694427:PALPR_RS11005
uniprot id: E4T6J3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

694427:PALPR RS14160
gene id: 694427:PALPR_RS14160
uniprot id: E4T8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

694427:PALPR RS01745
gene id: 694427:PALPR_RS01745
uniprot id: E4T1B8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

694427:PALPR RS11135
gene id: 694427:PALPR_RS11135
uniprot id: E4T6M2
names: Similarity
messages: Belongs to the sigma-54 factor family.

694427:PALPR RS07060
gene id: 694427:PALPR_RS07060
uniprot id: E4T4B2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

694427:PALPR RS05505
gene id: 694427:PALPR_RS05505
uniprot id: E4T3F9
names: Similarity
messages: Belongs to the glutamate synthase family.

694427:PALPR RS01785
gene id: 694427:PALPR_RS01785
uniprot id: E4T1C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

694427:PALPR RS08115
gene id: 694427:PALPR_RS08115
uniprot id: E4T4X4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

694427:PALPR RS04420
gene id: 694427:PALPR_RS04420
uniprot id: E4T2V1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

694427:PALPR RS05365
gene id: 694427:PALPR_RS05365
uniprot id: E4T3D3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

694427:PALPR RS14440
gene id: 694427:PALPR_RS14440
uniprot id: E4T8I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

694427:PALPR RS14780
gene id: 694427:PALPR_RS14780
uniprot id: E4T0N5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

694427:PALPR RS00960
gene id: 694427:PALPR_RS00960
uniprot id: E4T0X0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

694427:PALPR RS15130
gene id: 694427:PALPR_RS15130
uniprot id: E4T8R1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

694427:PALPR RS12300
gene id: 694427:PALPR_RS12300
uniprot id: E4T798
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

694427:PALPR RS12870
gene id: 694427:PALPR_RS12870
uniprot id: E4T7L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

694427:PALPR RS04605
gene id: 694427:PALPR_RS04605
uniprot id: E4T2Y9
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

694427:PALPR RS12750
gene id: 694427:PALPR_RS12750
uniprot id: E4T7J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS12695
gene id: 694427:PALPR_RS12695
uniprot id: E4T7I0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS12790
gene id: 694427:PALPR_RS12790
uniprot id: E4T7J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

694427:PALPR RS11470
gene id: 694427:PALPR_RS11470
uniprot id: E4T6T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

694427:PALPR RS03765
gene id: 694427:PALPR_RS03765
uniprot id: E4T2H4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

694427:PALPR RS07215
gene id: 694427:PALPR_RS07215
uniprot id: E4T4E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

694427:PALPR RS15395
gene id: 694427:PALPR_RS15395
uniprot id: E4T5B7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS13555
gene id: 694427:PALPR_RS13555
uniprot id: E4T807
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS02685
gene id: 694427:PALPR_RS02685
uniprot id: E4T1V8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS01885
gene id: 694427:PALPR_RS01885
uniprot id: E4T1E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

694427:PALPR RS03690
gene id: 694427:PALPR_RS03690
uniprot id: E4T2G1
names: Similarity
messages: Belongs to the aldose epimerase family.

694427:PALPR RS15180
gene id: 694427:PALPR_RS15180
uniprot id: E4T8S0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

694427:PALPR RS00600
gene id: 694427:PALPR_RS00600
uniprot id: E4T092
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS10345
gene id: 694427:PALPR_RS10345
uniprot id: E4T657
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

694427:PALPR RS06530
gene id: 694427:PALPR_RS06530
uniprot id: E4T409
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

694427:PALPR RS12475
gene id: 694427:PALPR_RS12475
uniprot id: E4T7D4
names: Similarity
messages: Belongs to the peptidase S41A family.

694427:PALPR RS06190
gene id: 694427:PALPR_RS06190
uniprot id: E4T3U5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

694427:PALPR RS04940
gene id: 694427:PALPR_RS04940
uniprot id: E4T354
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

694427:PALPR RS05145
gene id: 694427:PALPR_RS05145
uniprot id: E4T392
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS11715
gene id: 694427:PALPR_RS11715
uniprot id: E4T6Y7
names: Similarity
messages: Belongs to the XseB family.

694427:PALPR RS06495
gene id: 694427:PALPR_RS06495
uniprot id: E4T404
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

694427:PALPR RS01000
gene id: 694427:PALPR_RS01000
uniprot id: E4T0X8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

694427:PALPR RS04695
gene id: 694427:PALPR_RS04695
uniprot id: E4T304
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

694427:PALPR RS14990
gene id: 694427:PALPR_RS14990
uniprot id: E4T8N2
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS12890
gene id: 694427:PALPR_RS12890
uniprot id: E4T7L9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS08295
gene id: 694427:PALPR_RS08295
uniprot id: E4T510
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

694427:PALPR RS00880
gene id: 694427:PALPR_RS00880
uniprot id: E4T0H4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS00375
gene id: 694427:PALPR_RS00375
uniprot id: E4T0W1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

694427:PALPR RS03145
gene id: 694427:PALPR_RS03145
uniprot id: E4T251
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

694427:PALPR RS08025
gene id: 694427:PALPR_RS08025
uniprot id: E4T4V7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

694427:PALPR RS13560
gene id: 694427:PALPR_RS13560
uniprot id: E4T808
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS01100
gene id: 694427:PALPR_RS01100
uniprot id: E4T0Z8
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14400
gene id: 694427:PALPR_RS14400
uniprot id: E4T8H9
names: Similarity
messages: Belongs to the TrpC family.

694427:PALPR RS08700
gene id: 694427:PALPR_RS08700
uniprot id: E4T585
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

694427:PALPR RS10950
gene id: 694427:PALPR_RS10950
uniprot id: E4T6I3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS07555
gene id: 694427:PALPR_RS07555
uniprot id: E4T4L3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS10100
gene id: 694427:PALPR_RS10100
uniprot id: E4T608
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

694427:PALPR RS09965
gene id: 694427:PALPR_RS09965
uniprot id: E4T5Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

694427:PALPR RS12730
gene id: 694427:PALPR_RS12730
uniprot id: E4T7I8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

694427:PALPR RS15125
gene id: 694427:PALPR_RS15125
uniprot id: E4T8R0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

694427:PALPR RS01575
gene id: 694427:PALPR_RS01575
uniprot id: E4T198
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS01935
gene id: 694427:PALPR_RS01935
uniprot id: E4T1F6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS13100
gene id: 694427:PALPR_RS13100
uniprot id: E4T7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

694427:PALPR RS12395
gene id: 694427:PALPR_RS12395
uniprot id: E4T7B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

694427:PALPR RS04210
gene id: 694427:PALPR_RS04210
uniprot id: E4T2R0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

694427:PALPR RS03930
gene id: 694427:PALPR_RS03930
uniprot id: E4T2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

694427:PALPR RS03955
gene id: 694427:PALPR_RS03955
uniprot id: E4T2L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

694427:PALPR RS10790
gene id: 694427:PALPR_RS10790
uniprot id: E4T6F0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

694427:PALPR RS08995
gene id: 694427:PALPR_RS08995
uniprot id: E4T5E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS04040
gene id: 694427:PALPR_RS04040
uniprot id: E4T2M7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS06870
gene id: 694427:PALPR_RS06870
uniprot id: E4T475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

694427:PALPR RS15550
gene id: 694427:PALPR_RS15550
uniprot id: E4T7S4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS08630
gene id: 694427:PALPR_RS08630
uniprot id: E4T571
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

694427:PALPR RS05170
gene id: 694427:PALPR_RS05170
uniprot id: E4T397
names: Similarity
messages: Belongs to the citrate synthase family.

694427:PALPR RS04775
gene id: 694427:PALPR_RS04775
uniprot id: E4T321
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS02420
gene id: 694427:PALPR_RS02420
uniprot id: E4T1Q4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

694427:PALPR RS01770
gene id: 694427:PALPR_RS01770
uniprot id: E4T1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

694427:PALPR RS02495
gene id: 694427:PALPR_RS02495
uniprot id: E4T1R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

694427:PALPR RS12835
gene id: 694427:PALPR_RS12835
uniprot id: E4T7K8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

694427:PALPR RS00235
gene id: 694427:PALPR_RS00235
uniprot id: E4T0T2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

694427:PALPR RS01475
gene id: 694427:PALPR_RS01475
uniprot id: E4T178
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

694427:PALPR RS06230
gene id: 694427:PALPR_RS06230
uniprot id: E4T3V2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

694427:PALPR RS09830
gene id: 694427:PALPR_RS09830
uniprot id: E4T5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

694427:PALPR RS01630
gene id: 694427:PALPR_RS01630
uniprot id: E4T0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS01795
gene id: 694427:PALPR_RS01795
uniprot id: E4T1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

694427:PALPR RS01085
gene id: 694427:PALPR_RS01085
uniprot id: E4T0Z5
names: Similarity
messages: Belongs to the transketolase family.

694427:PALPR RS01160
gene id: 694427:PALPR_RS01160
uniprot id: E4T110
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

694427:PALPR RS00740
gene id: 694427:PALPR_RS00740
uniprot id: E4T0F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

694427:PALPR RS07570
gene id: 694427:PALPR_RS07570
uniprot id: E4T4L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

694427:PALPR RS11370
gene id: 694427:PALPR_RS11370
uniprot id: E4T6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

694427:PALPR RS11540
gene id: 694427:PALPR_RS11540
uniprot id: E4T6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

694427:PALPR RS14240
gene id: 694427:PALPR_RS14240
uniprot id: E4T8E6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

694427:PALPR RS02170
gene id: 694427:PALPR_RS02170
uniprot id: E4T1K5
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS07735
gene id: 694427:PALPR_RS07735
uniprot id: E4T4Q0
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS09245
gene id: 694427:PALPR_RS09245
uniprot id: E4T5J3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06760
gene id: 694427:PALPR_RS06760
uniprot id: E4T454
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

694427:PALPR RS13515
gene id: 694427:PALPR_RS13515
uniprot id: E4T7Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS08950
gene id: 694427:PALPR_RS08950
uniprot id: E4T5D6
names: Similarity
messages: Belongs to the thioredoxin family.

694427:PALPR RS12815
gene id: 694427:PALPR_RS12815
uniprot id: E4T7K4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

694427:PALPR RS04885
gene id: 694427:PALPR_RS04885
uniprot id: E4T342
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

694427:PALPR RS07730
gene id: 694427:PALPR_RS07730
uniprot id: E4T4P9
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS08130
gene id: 694427:PALPR_RS08130
uniprot id: E4T4X7
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

694427:PALPR RS06510
gene id: 694427:PALPR_RS06510
uniprot id: E4T407
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

694427:PALPR RS07480
gene id: 694427:PALPR_RS07480
uniprot id: E4T4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

694427:PALPR RS00585
gene id: 694427:PALPR_RS00585
uniprot id: E4T089
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS08695
gene id: 694427:PALPR_RS08695
uniprot id: E4T584
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

694427:PALPR RS05515
gene id: 694427:PALPR_RS05515
uniprot id: E4T3G1
names: Similarity
messages: Belongs to the asparagine synthetase family.

694427:PALPR RS07070
gene id: 694427:PALPR_RS07070
uniprot id: E4T4B4
names: Similarity
messages: Belongs to the ArsC family.

694427:PALPR RS14365
gene id: 694427:PALPR_RS14365
uniprot id: E4T8H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

694427:PALPR RS07500
gene id: 694427:PALPR_RS07500
uniprot id: E4T4K2
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS00785
gene id: 694427:PALPR_RS00785
uniprot id: E4T0G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

694427:PALPR RS05370
gene id: 694427:PALPR_RS05370
uniprot id: E4T3D4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

694427:PALPR RS14620
gene id: 694427:PALPR_RS14620
uniprot id: E4T0K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS13590
gene id: 694427:PALPR_RS13590
uniprot id: E4T814
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS12880
gene id: 694427:PALPR_RS12880
uniprot id: E4T7L7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

694427:PALPR RS04585
gene id: 694427:PALPR_RS04585
uniprot id: E4T2Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS09015
gene id: 694427:PALPR_RS09015
uniprot id: E4T5E9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS12590
gene id: 694427:PALPR_RS12590
uniprot id: E4T7F8
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS06625
gene id: 694427:PALPR_RS06625
uniprot id: E4T428
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

694427:PALPR RS02365
gene id: 694427:PALPR_RS02365
uniprot id: E4T1P2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

694427:PALPR RS10980
gene id: 694427:PALPR_RS10980
uniprot id: E4T6I9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

694427:PALPR RS15100
gene id: 694427:PALPR_RS15100
uniprot id: E4T8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

694427:PALPR RS05330
gene id: 694427:PALPR_RS05330
uniprot id: E4T3C6
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14310
gene id: 694427:PALPR_RS14310
uniprot id: E4T8G0
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS10550
gene id: 694427:PALPR_RS10550
uniprot id: E4T6A0
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

694427:PALPR RS08490
gene id: 694427:PALPR_RS08490
uniprot id: E4T549
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS10055
gene id: 694427:PALPR_RS10055
uniprot id: E4T5Z8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

694427:PALPR RS06395
gene id: 694427:PALPR_RS06395
uniprot id: E4T3Y4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

694427:PALPR RS06630
gene id: 694427:PALPR_RS06630
uniprot id: E4T429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

694427:PALPR RS15055
gene id: 694427:PALPR_RS15055
uniprot id: E4T8P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

694427:PALPR RS06875
gene id: 694427:PALPR_RS06875
uniprot id: E4T476
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS14775
gene id: 694427:PALPR_RS14775
uniprot id: E4T0N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

694427:PALPR RS14370
gene id: 694427:PALPR_RS14370
uniprot id: E4T8H2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS05210
gene id: 694427:PALPR_RS05210
uniprot id: E4T3A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

694427:PALPR RS08060
gene id: 694427:PALPR_RS08060
uniprot id: E4T4W4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

694427:PALPR RS09130
gene id: 694427:PALPR_RS09130
uniprot id: E4T5H0
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS05835
gene id: 694427:PALPR_RS05835
uniprot id: E4T3M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

694427:PALPR RS01045
gene id: 694427:PALPR_RS01045
uniprot id: E4T0Y7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

694427:PALPR RS09770
gene id: 694427:PALPR_RS09770
uniprot id: E4T5U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

694427:PALPR RS02405
gene id: 694427:PALPR_RS02405
uniprot id: E4T1Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS01780
gene id: 694427:PALPR_RS01780
uniprot id: E4T1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

694427:PALPR RS04060
gene id: 694427:PALPR_RS04060
uniprot id: E4T2N3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

694427:PALPR RS15245
gene id: 694427:PALPR_RS15245
uniprot id: E4T1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

694427:PALPR RS10015
gene id: 694427:PALPR_RS10015
uniprot id: E4T5Z1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS03575
gene id: 694427:PALPR_RS03575
uniprot id: E4T2D8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

694427:PALPR RS02215
gene id: 694427:PALPR_RS02215
uniprot id: E4T1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS12165
gene id: 694427:PALPR_RS12165
uniprot id: E4T772
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

694427:PALPR RS03920
gene id: 694427:PALPR_RS03920
uniprot id: E4T2K4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

694427:PALPR RS13880
gene id: 694427:PALPR_RS13880
uniprot id: E4T874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

694427:PALPR RS07005
gene id: 694427:PALPR_RS07005
uniprot id: E4T4A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS02690
gene id: 694427:PALPR_RS02690
uniprot id: E4T1V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

694427:PALPR RS00955
gene id: 694427:PALPR_RS00955
uniprot id: E4T0W9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

694427:PALPR RS11190
gene id: 694427:PALPR_RS11190
uniprot id: E4T6N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

694427:PALPR RS02840
gene id: 694427:PALPR_RS02840
uniprot id: E4T1Z1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

694427:PALPR RS08450
gene id: 694427:PALPR_RS08450
uniprot id: E4T541
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

694427:PALPR RS05470
gene id: 694427:PALPR_RS05470
uniprot id: E4T3F2
names: Similarity
messages: Belongs to the P(II) protein family.

694427:PALPR RS03830
gene id: 694427:PALPR_RS03830
uniprot id: E4T2I7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

694427:PALPR RS03780
gene id: 694427:PALPR_RS03780
uniprot id: E4T2H7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

694427:PALPR RS03175
gene id: 694427:PALPR_RS03175
uniprot id: E4T258
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

694427:PALPR RS10770
gene id: 694427:PALPR_RS10770
uniprot id: E4T6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

694427:PALPR RS05840
gene id: 694427:PALPR_RS05840
uniprot id: E4T3M7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

694427:PALPR RS06960
gene id: 694427:PALPR_RS06960
uniprot id: E4T493
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

694427:PALPR RS08260
gene id: 694427:PALPR_RS08260
uniprot id: E4T503
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS00945
gene id: 694427:PALPR_RS00945
uniprot id: E4T0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

694427:PALPR RS06415
gene id: 694427:PALPR_RS06415
uniprot id: E4T3Y8
names: Similarity
messages: Belongs to the AIR synthase family.

694427:PALPR RS15050
gene id: 694427:PALPR_RS15050
uniprot id: E4T8P5
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS02305
gene id: 694427:PALPR_RS02305
uniprot id: E4T1N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS03355
gene id: 694427:PALPR_RS03355
uniprot id: E4T294
names: Similarity
messages: Belongs to the YicC/YloC family.

694427:PALPR RS08740
gene id: 694427:PALPR_RS08740
uniprot id: E4T592
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

694427:PALPR RS07235
gene id: 694427:PALPR_RS07235
uniprot id: E4T4E7
names: Similarity
messages: Belongs to the Skp family.

694427:PALPR RS11975
gene id: 694427:PALPR_RS11975
uniprot id: E4T736
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

694427:PALPR RS15600
gene id: 694427:PALPR_RS15600
uniprot id: E4T0M3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

694427:PALPR RS12345
gene id: 694427:PALPR_RS12345
uniprot id: E4T7A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

694427:PALPR RS03655
gene id: 694427:PALPR_RS03655
uniprot id: E4T2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

694427:PALPR RS15115
gene id: 694427:PALPR_RS15115
uniprot id: E4T8Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

694427:PALPR RS08245
gene id: 694427:PALPR_RS08245
uniprot id: E4T500
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

694427:PALPR RS06055
gene id: 694427:PALPR_RS06055
uniprot id: E4T3S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

694427:PALPR RS07510
gene id: 694427:PALPR_RS07510
uniprot id: E4T4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

694427:PALPR RS06195
gene id: 694427:PALPR_RS06195
uniprot id: E4T3U6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

694427:PALPR RS15065
gene id: 694427:PALPR_RS15065
uniprot id: E4T8P8
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

694427:PALPR RS01065
gene id: 694427:PALPR_RS01065
uniprot id: E4T0Z1
names: Similarity
messages: Belongs to the UPF0166 family.

694427:PALPR RS14665
gene id: 694427:PALPR_RS14665
uniprot id: E4T0L2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

694427:PALPR RS06480
gene id: 694427:PALPR_RS06480
uniprot id: E4T401
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS10690
gene id: 694427:PALPR_RS10690
uniprot id: E4T6D0
names: Similarity
messages: Belongs to the aldose epimerase family.

694427:PALPR RS12195
gene id: 694427:PALPR_RS12195
uniprot id: E4T776
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

694427:PALPR RS06185
gene id: 694427:PALPR_RS06185
uniprot id: E4T3U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

694427:PALPR RS09305
gene id: 694427:PALPR_RS09305
uniprot id: E4T5K5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

694427:PALPR RS01700
gene id: 694427:PALPR_RS01700
uniprot id: E4T1A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

694427:PALPR RS02140
gene id: 694427:PALPR_RS02140
uniprot id: E4T1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

694427:PALPR RS00200
gene id: 694427:PALPR_RS00200
uniprot id: E4T0S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS06325
gene id: 694427:PALPR_RS06325
uniprot id: E4T3X0
names: Similarity
messages: Belongs to the tannase family.

694427:PALPR RS07650
gene id: 694427:PALPR_RS07650
uniprot id: E4T4N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

694427:PALPR RS06310
gene id: 694427:PALPR_RS06310
uniprot id: E4T3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

694427:PALPR RS04375
gene id: 694427:PALPR_RS04375
uniprot id: E4T2U3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14255
gene id: 694427:PALPR_RS14255
uniprot id: E4T8E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS02920
gene id: 694427:PALPR_RS02920
uniprot id: E4T207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

694427:PALPR RS03490
gene id: 694427:PALPR_RS03490
uniprot id: E4T2C1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS12390
gene id: 694427:PALPR_RS12390
uniprot id: E4T7B6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

694427:PALPR RS09825
gene id: 694427:PALPR_RS09825
uniprot id: E4T5V3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

694427:PALPR RS14005
gene id: 694427:PALPR_RS14005
uniprot id: E4T899
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

694427:PALPR RS03345
gene id: 694427:PALPR_RS03345
uniprot id: E4T292
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

694427:PALPR RS00840
gene id: 694427:PALPR_RS00840
uniprot id: E4T0G7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

694427:PALPR RS01320
gene id: 694427:PALPR_RS01320
uniprot id: E4T144
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14130
gene id: 694427:PALPR_RS14130
uniprot id: E4T8C4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS14815
gene id: 694427:PALPR_RS14815
uniprot id: E4T0P1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

694427:PALPR RS01360
gene id: 694427:PALPR_RS01360
uniprot id: E4T154
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

694427:PALPR RS13265
gene id: 694427:PALPR_RS13265
uniprot id: E4T7V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

694427:PALPR RS00290
gene id: 694427:PALPR_RS00290
uniprot id: E4T0U3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

694427:PALPR RS02540
gene id: 694427:PALPR_RS02540
uniprot id: E4T1S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

694427:PALPR RS09720
gene id: 694427:PALPR_RS09720
uniprot id: E4T5T4
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS01620
gene id: 694427:PALPR_RS01620
uniprot id: E4T0A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

694427:PALPR RS04895
gene id: 694427:PALPR_RS04895
uniprot id: E4T344
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS13390
gene id: 694427:PALPR_RS13390
uniprot id: E4T7X4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

694427:PALPR RS09565
gene id: 694427:PALPR_RS09565
uniprot id: E4T5Q3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS09365
gene id: 694427:PALPR_RS09365
uniprot id: E4T5L7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

694427:PALPR RS13575
gene id: 694427:PALPR_RS13575
uniprot id: E4T811
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

694427:PALPR RS05980
gene id: 694427:PALPR_RS05980
uniprot id: E4T3Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

694427:PALPR RS14265
gene id: 694427:PALPR_RS14265
uniprot id: E4T8F1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

694427:PALPR RS06225
gene id: 694427:PALPR_RS06225
uniprot id: E4T3V1
names: Similarity
messages: Belongs to the SufE family.

694427:PALPR RS09580
gene id: 694427:PALPR_RS09580
uniprot id: E4T5Q6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

694427:PALPR RS05860
gene id: 694427:PALPR_RS05860
uniprot id: E4T3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

694427:PALPR RS12910
gene id: 694427:PALPR_RS12910
uniprot id: E4T7M3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

694427:PALPR RS07085
gene id: 694427:PALPR_RS07085
uniprot id: E4T4B7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

694427:PALPR RS06710
gene id: 694427:PALPR_RS06710
uniprot id: E4T444
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS09090
gene id: 694427:PALPR_RS09090
uniprot id: E4T5G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

694427:PALPR RS04050
gene id: 694427:PALPR_RS04050
uniprot id: E4T2N1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

694427:PALPR RS08670
gene id: 694427:PALPR_RS08670
uniprot id: E4T579
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS07225
gene id: 694427:PALPR_RS07225
uniprot id: E4T4E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

694427:PALPR RS12265
gene id: 694427:PALPR_RS12265
uniprot id: E4T791
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

694427:PALPR RS13350
gene id: 694427:PALPR_RS13350
uniprot id: E4T7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

694427:PALPR RS14410
gene id: 694427:PALPR_RS14410
uniprot id: E4T8I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

694427:PALPR RS12220
gene id: 694427:PALPR_RS12220
uniprot id: E4T781
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

694427:PALPR RS09185
gene id: 694427:PALPR_RS09185
uniprot id: E4T5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

694427:PALPR RS14085
gene id: 694427:PALPR_RS14085
uniprot id: E4T8B4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

694427:PALPR RS06890
gene id: 694427:PALPR_RS06890
uniprot id: E4T480
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

694427:PALPR RS01815
gene id: 694427:PALPR_RS01815
uniprot id: E4T1D2
names: Similarity
messages: Belongs to the UPF0047 family.

694427:PALPR RS03155
gene id: 694427:PALPR_RS03155
uniprot id: E4T253
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

694427:PALPR RS11935
gene id: 694427:PALPR_RS11935
uniprot id: E4T728
names: Similarity
messages: Belongs to the NDK family.

694427:PALPR RS12960
gene id: 694427:PALPR_RS12960
uniprot id: E4T7N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

694427:PALPR RS08680
gene id: 694427:PALPR_RS08680
uniprot id: E4T581
names: Similarity
messages: Belongs to the serpin family.

694427:PALPR RS10905
gene id: 694427:PALPR_RS10905
uniprot id: E4T6H4
names: Similarity
messages: Belongs to the LOG family.

694427:PALPR RS03720
gene id: 694427:PALPR_RS03720
uniprot id: E4T2G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

694427:PALPR RS04365
gene id: 694427:PALPR_RS04365
uniprot id: E4T2U1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS10400
gene id: 694427:PALPR_RS10400
uniprot id: E4T668
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

694427:PALPR RS13625
gene id: 694427:PALPR_RS13625
uniprot id: E4T821
names: Subcellular Location Annotation
messages: Cytoplasm

694427:PALPR RS12805
gene id: 694427:PALPR_RS12805
uniprot id: E4T7K2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

694427:PALPR RS06105
gene id: 694427:PALPR_RS06105
uniprot id: E4T3T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

694427:PALPR RS06810
gene id: 694427:PALPR_RS06810
uniprot id: E4T464
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

694427:PALPR RS00770
gene id: 694427:PALPR_RS00770
uniprot id: E4T0F7
names: Similarity
messages: Belongs to the DEAD box helicase family.

694427:PALPR RS12355
gene id: 694427:PALPR_RS12355
uniprot id: E4T7A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

694427:PALPR RS02380
gene id: 694427:PALPR_RS02380
uniprot id: E4T1P5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS11220
gene id: 694427:PALPR_RS11220
uniprot id: E4T6N9
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS03825
gene id: 694427:PALPR_RS03825
uniprot id: E4T2I6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

694427:PALPR RS04275
gene id: 694427:PALPR_RS04275
uniprot id: E4T2S3
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

694427:PALPR RS14345
gene id: 694427:PALPR_RS14345
uniprot id: E4T8G7
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS05080
gene id: 694427:PALPR_RS05080
uniprot id: E4T379
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS01625
gene id: 694427:PALPR_RS01625
uniprot id: E4T0A3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

694427:PALPR RS06070
gene id: 694427:PALPR_RS06070
uniprot id: E4T3S3
names: Similarity
messages: Belongs to the HSP15 family.

694427:PALPR RS08180
gene id: 694427:PALPR_RS08180
uniprot id: E4T4Y7
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS12745
gene id: 694427:PALPR_RS12745
uniprot id: E4T7J1
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

694427:PALPR RS08820
gene id: 694427:PALPR_RS08820
uniprot id: E4T5B0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

694427:PALPR RS06580
gene id: 694427:PALPR_RS06580
uniprot id: E4T419
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14900
gene id: 694427:PALPR_RS14900
uniprot id: E4T8L3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

694427:PALPR RS09985
gene id: 694427:PALPR_RS09985
uniprot id: E4T5Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

694427:PALPR RS10380
gene id: 694427:PALPR_RS10380
uniprot id: E4T664
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

694427:PALPR RS01470
gene id: 694427:PALPR_RS01470
uniprot id: E4T177
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

694427:PALPR RS11665
gene id: 694427:PALPR_RS11665
uniprot id: E4T6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

694427:PALPR RS10810
gene id: 694427:PALPR_RS10810
uniprot id: E4T6F4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS14455
gene id: 694427:PALPR_RS14455
uniprot id: E4T8J0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

694427:PALPR RS12120
gene id: 694427:PALPR_RS12120
uniprot id: E4T763
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

694427:PALPR RS07960
gene id: 694427:PALPR_RS07960
uniprot id: E4T4U4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

694427:PALPR RS11755
gene id: 694427:PALPR_RS11755
uniprot id: E4T6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

694427:PALPR RS04930
gene id: 694427:PALPR_RS04930
uniprot id: E4T351
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

694427:PALPR RS06060
gene id: 694427:PALPR_RS06060
uniprot id: E4T3S1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

694427:PALPR RS04245
gene id: 694427:PALPR_RS04245
uniprot id: E4T2R7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

694427:PALPR RS06260
gene id: 694427:PALPR_RS06260
uniprot id: E4T3V7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

694427:PALPR RS10505
gene id: 694427:PALPR_RS10505
uniprot id: E4T690
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS10520
gene id: 694427:PALPR_RS10520
uniprot id: E4T694
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

694427:PALPR RS09380
gene id: 694427:PALPR_RS09380
uniprot id: E4T5M0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

694427:PALPR RS07055
gene id: 694427:PALPR_RS07055
uniprot id: E4T4B1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS12545
gene id: 694427:PALPR_RS12545
uniprot id: E4T7E8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS05155
gene id: 694427:PALPR_RS05155
uniprot id: E4T394
names: Similarity
messages: Belongs to the pirin family.

694427:PALPR RS11735
gene id: 694427:PALPR_RS11735
uniprot id: E4T6Z1
names: Similarity
messages: Belongs to the RecJ family.

694427:PALPR RS02645
gene id: 694427:PALPR_RS02645
uniprot id: E4T1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

694427:PALPR RS06290
gene id: 694427:PALPR_RS06290
uniprot id: E4T3W3
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

694427:PALPR RS02930
gene id: 694427:PALPR_RS02930
uniprot id: E4T209
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

694427:PALPR RS03140
gene id: 694427:PALPR_RS03140
uniprot id: E4T250
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

694427:PALPR RS00480
gene id: 694427:PALPR_RS00480
uniprot id: E4T069
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

694427:PALPR RS12285
gene id: 694427:PALPR_RS12285
uniprot id: E4T795
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

694427:PALPR RS02530
gene id: 694427:PALPR_RS02530
uniprot id: E4T1S6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

694427:PALPR RS00700
gene id: 694427:PALPR_RS00700
uniprot id: E4T0E3
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS14405
gene id: 694427:PALPR_RS14405
uniprot id: E4T8I0
names: Similarity
messages: Belongs to the TrpF family.

694427:PALPR RS11075
gene id: 694427:PALPR_RS11075
uniprot id: E4T6L0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

694427:PALPR RS01335
gene id: 694427:PALPR_RS01335
uniprot id: E4T148
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS03125
gene id: 694427:PALPR_RS03125
uniprot id: E4T247
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

694427:PALPR RS04970
gene id: 694427:PALPR_RS04970
uniprot id: E4T360
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

694427:PALPR RS01220
gene id: 694427:PALPR_RS01220
uniprot id: E4T122
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS12225
gene id: 694427:PALPR_RS12225
uniprot id: E4T782
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

694427:PALPR RS10990
gene id: 694427:PALPR_RS10990
uniprot id: E4T6J1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

694427:PALPR RS09225
gene id: 694427:PALPR_RS09225
uniprot id: E4T5I8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

694427:PALPR RS09040
gene id: 694427:PALPR_RS09040
uniprot id: E4T5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS15070
gene id: 694427:PALPR_RS15070
uniprot id: E4T8P9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

694427:PALPR RS10390
gene id: 694427:PALPR_RS10390
uniprot id: E4T666
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

694427:PALPR RS13155
gene id: 694427:PALPR_RS13155
uniprot id: E4T7S2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

694427:PALPR RS06485
gene id: 694427:PALPR_RS06485
uniprot id: E4T402
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

694427:PALPR RS04095
gene id: 694427:PALPR_RS04095
uniprot id: E4T2P0
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS00870
gene id: 694427:PALPR_RS00870
uniprot id: E4T0H2
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS12915
gene id: 694427:PALPR_RS12915
uniprot id: E4T7M4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

694427:PALPR RS00995
gene id: 694427:PALPR_RS00995
uniprot id: E4T0X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

694427:PALPR RS09555
gene id: 694427:PALPR_RS09555
uniprot id: E4T5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

694427:PALPR RS00350
gene id: 694427:PALPR_RS00350
uniprot id: E4T0V6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

694427:PALPR RS01260
gene id: 694427:PALPR_RS01260
uniprot id: E4T130
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS07380
gene id: 694427:PALPR_RS07380
uniprot id: E4T4H8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

694427:PALPR RS11745
gene id: 694427:PALPR_RS11745
uniprot id: E4T6Z3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

694427:PALPR RS04850
gene id: 694427:PALPR_RS04850
uniprot id: E4T335
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

694427:PALPR RS00520
gene id: 694427:PALPR_RS00520
uniprot id: E4T077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

694427:PALPR RS12900
gene id: 694427:PALPR_RS12900
uniprot id: E4T7M1
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

694427:PALPR RS02190
gene id: 694427:PALPR_RS02190
uniprot id: E4T1K9
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

694427:PALPR RS00755
gene id: 694427:PALPR_RS00755
uniprot id: E4T0F4
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

694427:PALPR RS10820
gene id: 694427:PALPR_RS10820
uniprot id: E4T6F6
names: Similarity
messages: Belongs to the GARS family.

694427:PALPR RS08805
gene id: 694427:PALPR_RS08805
uniprot id: E4T5A7
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

694427:PALPR RS08070
gene id: 694427:PALPR_RS08070
uniprot id: E4T4W6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

694427:PALPR RS09700
gene id: 694427:PALPR_RS09700
uniprot id: E4T5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

694427:PALPR RS08735
gene id: 694427:PALPR_RS08735
uniprot id: E4T591
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

694427:PALPR RS11275
gene id: 694427:PALPR_RS11275
uniprot id: E4T6Q0
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS01090
gene id: 694427:PALPR_RS01090
uniprot id: E4T0Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

694427:PALPR RS12380
gene id: 694427:PALPR_RS12380
uniprot id: E4T7B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

694427:PALPR RS13890
gene id: 694427:PALPR_RS13890
uniprot id: E4T876
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

694427:PALPR RS01185
gene id: 694427:PALPR_RS01185
uniprot id: E4T115
names: Similarity
messages: Belongs to the aspartokinase family.

694427:PALPR RS09520
gene id: 694427:PALPR_RS09520
uniprot id: E4T5P4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

694427:PALPR RS09050
gene id: 694427:PALPR_RS09050
uniprot id: E4T5F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

694427:PALPR RS13130
gene id: 694427:PALPR_RS13130
uniprot id: E4T7R6
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS12875
gene id: 694427:PALPR_RS12875
uniprot id: E4T7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

694427:PALPR RS10920
gene id: 694427:PALPR_RS10920
uniprot id: E4T6H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

694427:PALPR RS11415
gene id: 694427:PALPR_RS11415
uniprot id: E4T6S8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

694427:PALPR RS05500
gene id: 694427:PALPR_RS05500
uniprot id: E4T3F8
names: Similarity
messages: Belongs to the glutamine synthetase family.

694427:PALPR RS01715
gene id: 694427:PALPR_RS01715
uniprot id: E4T1B2
names: Similarity
messages: Belongs to the peptidase C40 family.

694427:PALPR RS02735
gene id: 694427:PALPR_RS02735
uniprot id: E4T1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

694427:PALPR RS06460
gene id: 694427:PALPR_RS06460
uniprot id: E4T3Z7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

694427:PALPR RS00140
gene id: 694427:PALPR_RS00140
uniprot id: E4T0R2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS10930
gene id: 694427:PALPR_RS10930
uniprot id: E4T6H9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

694427:PALPR RS01800
gene id: 694427:PALPR_RS01800
uniprot id: E4T1C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

694427:PALPR RS09695
gene id: 694427:PALPR_RS09695
uniprot id: E4T5S9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS12280
gene id: 694427:PALPR_RS12280
uniprot id: E4T794
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

694427:PALPR RS12110
gene id: 694427:PALPR_RS12110
uniprot id: E4T761
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS10600
gene id: 694427:PALPR_RS10600
uniprot id: E4T6B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

694427:PALPR RS04565
gene id: 694427:PALPR_RS04565
uniprot id: E4T2Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS14430
gene id: 694427:PALPR_RS14430
uniprot id: E4T8I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

694427:PALPR RS08620
gene id: 694427:PALPR_RS08620
uniprot id: E4T569
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

694427:PALPR RS06220
gene id: 694427:PALPR_RS06220
uniprot id: E4T3V0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

694427:PALPR RS12995
gene id: 694427:PALPR_RS12995
uniprot id: E4T7P1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS12080
gene id: 694427:PALPR_RS12080
uniprot id: E4T755
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

694427:PALPR RS02865
gene id: 694427:PALPR_RS02865
uniprot id: E4T1Z6
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

694427:PALPR RS12430
gene id: 694427:PALPR_RS12430
uniprot id: E4T7C5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS12895
gene id: 694427:PALPR_RS12895
uniprot id: E4T7M0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

694427:PALPR RS12100
gene id: 694427:PALPR_RS12100
uniprot id: E4T759
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

694427:PALPR RS05265
gene id: 694427:PALPR_RS05265
uniprot id: E4T3B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

694427:PALPR RS14570
gene id: 694427:PALPR_RS14570
uniprot id: E4T0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

694427:PALPR RS08830
gene id: 694427:PALPR_RS08830
uniprot id: E4T5B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

694427:PALPR RS00450
gene id: 694427:PALPR_RS00450
uniprot id: E4T062
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS04950
gene id: 694427:PALPR_RS04950
uniprot id: E4T356
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

694427:PALPR RS13540
gene id: 694427:PALPR_RS13540
uniprot id: E4T804
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

694427:PALPR RS01150
gene id: 694427:PALPR_RS01150
uniprot id: E4T108
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

694427:PALPR RS10470
gene id: 694427:PALPR_RS10470
uniprot id: E4T683
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

694427:PALPR RS04055
gene id: 694427:PALPR_RS04055
uniprot id: E4T2N2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

694427:PALPR RS00775
gene id: 694427:PALPR_RS00775
uniprot id: E4T0F9
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS11700
gene id: 694427:PALPR_RS11700
uniprot id: E4T6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

694427:PALPR RS12785
gene id: 694427:PALPR_RS12785
uniprot id: E4T7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

694427:PALPR RS13930
gene id: 694427:PALPR_RS13930
uniprot id: E4T884
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

694427:PALPR RS08505
gene id: 694427:PALPR_RS08505
uniprot id: E4T552
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

694427:PALPR RS00780
gene id: 694427:PALPR_RS00780
uniprot id: E4T0G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

694427:PALPR RS09765
gene id: 694427:PALPR_RS09765
uniprot id: E4T5U3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06575
gene id: 694427:PALPR_RS06575
uniprot id: E4T418
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

694427:PALPR RS15235
gene id: 694427:PALPR_RS15235
uniprot id: E4T168
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

694427:PALPR RS08970
gene id: 694427:PALPR_RS08970
uniprot id: E4T5E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

694427:PALPR RS02755
gene id: 694427:PALPR_RS02755
uniprot id: E4T1X2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

694427:PALPR RS08110
gene id: 694427:PALPR_RS08110
uniprot id: E4T4X3
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

694427:PALPR RS03660
gene id: 694427:PALPR_RS03660
uniprot id: E4T2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS09620
gene id: 694427:PALPR_RS09620
uniprot id: E4T5R4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

694427:PALPR RS01290
gene id: 694427:PALPR_RS01290
uniprot id: E4T136
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

694427:PALPR RS12650
gene id: 694427:PALPR_RS12650
uniprot id: E4T7H0
names: Similarity
messages: Belongs to the UPF0597 family.

694427:PALPR RS14275
gene id: 694427:PALPR_RS14275
uniprot id: E4T8F3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

694427:PALPR RS13075
gene id: 694427:PALPR_RS13075
uniprot id: E4T7Q5
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

694427:PALPR RS05050
gene id: 694427:PALPR_RS05050
uniprot id: E4T374
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS13365
gene id: 694427:PALPR_RS13365
uniprot id: E4T7W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

694427:PALPR RS02855
gene id: 694427:PALPR_RS02855
uniprot id: E4T1Z4
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

694427:PALPR RS12400
gene id: 694427:PALPR_RS12400
uniprot id: E4T7B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

694427:PALPR RS05975
gene id: 694427:PALPR_RS05975
uniprot id: E4T3Q0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

694427:PALPR RS12470
gene id: 694427:PALPR_RS12470
uniprot id: E4T7D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

694427:PALPR RS08610
gene id: 694427:PALPR_RS08610
uniprot id: E4T567
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

694427:PALPR RS05715
gene id: 694427:PALPR_RS05715
uniprot id: E4T3K1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

694427:PALPR RS12275
gene id: 694427:PALPR_RS12275
uniprot id: E4T793
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

694427:PALPR RS07505
gene id: 694427:PALPR_RS07505
uniprot id: E4T4K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

694427:PALPR RS06840
gene id: 694427:PALPR_RS06840
uniprot id: E4T469
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

694427:PALPR RS05910
gene id: 694427:PALPR_RS05910
uniprot id: E4T3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

694427:PALPR RS13410
gene id: 694427:PALPR_RS13410
uniprot id: E4T7X7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

694427:PALPR RS09655
gene id: 694427:PALPR_RS09655
uniprot id: E4T5S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS13645
gene id: 694427:PALPR_RS13645
uniprot id: E4T825
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

694427:PALPR RS09200
gene id: 694427:PALPR_RS09200
uniprot id: E4T5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS07780
gene id: 694427:PALPR_RS07780
uniprot id: E4T4Q9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

694427:PALPR RS10540
gene id: 694427:PALPR_RS10540
uniprot id: E4T698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

694427:PALPR RS01420
gene id: 694427:PALPR_RS01420
uniprot id: E4T167
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

694427:PALPR RS04015
gene id: 694427:PALPR_RS04015
uniprot id: E4T2M2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

694427:PALPR RS06080
gene id: 694427:PALPR_RS06080
uniprot id: E4T3S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

694427:PALPR RS07125
gene id: 694427:PALPR_RS07125
uniprot id: E4T4C5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

694427:PALPR RS13905
gene id: 694427:PALPR_RS13905
uniprot id: E4T879
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

694427:PALPR RS04430
gene id: 694427:PALPR_RS04430
uniprot id: E4T2V3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS01905
gene id: 694427:PALPR_RS01905
uniprot id: E4T1F0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS13080
gene id: 694427:PALPR_RS13080
uniprot id: E4T7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

694427:PALPR RS06845
gene id: 694427:PALPR_RS06845
uniprot id: E4T470
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

694427:PALPR RS05580
gene id: 694427:PALPR_RS05580
uniprot id: E4T3H4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

694427:PALPR RS03390
gene id: 694427:PALPR_RS03390
uniprot id: E4T2A1
names: Similarity
messages: Belongs to the YjdM family.

694427:PALPR RS08625
gene id: 694427:PALPR_RS08625
uniprot id: E4T570
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

694427:PALPR RS04730
gene id: 694427:PALPR_RS04730
uniprot id: E4T311
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

694427:PALPR RS08370
gene id: 694427:PALPR_RS08370
uniprot id: E4T526
names: Similarity
messages: Belongs to the heat shock protein 90 family.

694427:PALPR RS06825
gene id: 694427:PALPR_RS06825
uniprot id: E4T467
names: Similarity
messages: Belongs to the P(II) protein family.

694427:PALPR RS12625
gene id: 694427:PALPR_RS12625
uniprot id: E4T7G5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS13915
gene id: 694427:PALPR_RS13915
uniprot id: E4T881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

694427:PALPR RS05845
gene id: 694427:PALPR_RS05845
uniprot id: E4T3M8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

694427:PALPR RS05770
gene id: 694427:PALPR_RS05770
uniprot id: E4T3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

694427:PALPR RS05700
gene id: 694427:PALPR_RS05700
uniprot id: E4T3J8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

694427:PALPR RS08325
gene id: 694427:PALPR_RS08325
uniprot id: E4T516
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

694427:PALPR RS05655
gene id: 694427:PALPR_RS05655
uniprot id: E4T3I9
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

694427:PALPR RS09175
gene id: 694427:PALPR_RS09175
uniprot id: E4T5I0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

694427:PALPR RS06365
gene id: 694427:PALPR_RS06365
uniprot id: E4T3X8
names: Similarity
messages: Belongs to the peptidase M16 family.

694427:PALPR RS01635
gene id: 694427:PALPR_RS01635
uniprot id: E4T0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

694427:PALPR RS11315
gene id: 694427:PALPR_RS11315
uniprot id: E4T6Q8
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS07340
gene id: 694427:PALPR_RS07340
uniprot id: E4T4H0
names: Subcellular Location Annotation
messages: Cytoplasm

694427:PALPR RS14970
gene id: 694427:PALPR_RS14970
uniprot id: E4T8M8
names: Similarity
messages: Belongs to the peptidase S41A family.

694427:PALPR RS10465
gene id: 694427:PALPR_RS10465
uniprot id: E4T682
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

694427:PALPR RS06115
gene id: 694427:PALPR_RS06115
uniprot id: E4T3T2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

694427:PALPR RS08120
gene id: 694427:PALPR_RS08120
uniprot id: E4T4X5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS13220
gene id: 694427:PALPR_RS13220
uniprot id: E4T7T7
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS03415
gene id: 694427:PALPR_RS03415
uniprot id: E4T2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

694427:PALPR RS04405
gene id: 694427:PALPR_RS04405
uniprot id: E4T2U8
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS00500
gene id: 694427:PALPR_RS00500
uniprot id: E4T073
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

694427:PALPR RS01585
gene id: 694427:PALPR_RS01585
uniprot id: E4T1A0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

694427:PALPR RS10340
gene id: 694427:PALPR_RS10340
uniprot id: E4T656
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

694427:PALPR RS00275
gene id: 694427:PALPR_RS00275
uniprot id: E4T0U0
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

694427:PALPR RS03350
gene id: 694427:PALPR_RS03350
uniprot id: E4T293
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

694427:PALPR RS05590
gene id: 694427:PALPR_RS05590
uniprot id: E4T3H6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

694427:PALPR RS09615
gene id: 694427:PALPR_RS09615
uniprot id: E4T5R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

694427:PALPR RS04815
gene id: 694427:PALPR_RS04815
uniprot id: E4T329
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

694427:PALPR RS10295
gene id: 694427:PALPR_RS10295
uniprot id: E4T647
names: Similarity
messages: Belongs to the DprA/Smf family.

694427:PALPR RS08010
gene id: 694427:PALPR_RS08010
uniprot id: E4T4V4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

694427:PALPR RS09570
gene id: 694427:PALPR_RS09570
uniprot id: E4T5Q4
names: Similarity
messages: Belongs to the UPF0102 family.

694427:PALPR RS10720
gene id: 694427:PALPR_RS10720
uniprot id: E4T6D6
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

694427:PALPR RS02390
gene id: 694427:PALPR_RS02390
uniprot id: E4T1P8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

694427:PALPR RS00245
gene id: 694427:PALPR_RS00245
uniprot id: E4T0T4
names: Similarity
messages: Belongs to the DEAD box helicase family.

694427:PALPR RS11330
gene id: 694427:PALPR_RS11330
uniprot id: E4T6R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

694427:PALPR RS02885
gene id: 694427:PALPR_RS02885
uniprot id: E4T200
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

694427:PALPR RS04000
gene id: 694427:PALPR_RS04000
uniprot id: E4T2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

694427:PALPR RS05110
gene id: 694427:PALPR_RS05110
uniprot id: E4T385
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

694427:PALPR RS03900
gene id: 694427:PALPR_RS03900
uniprot id: E4T2K0
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS10515
gene id: 694427:PALPR_RS10515
uniprot id: E4T693
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

694427:PALPR RS03755
gene id: 694427:PALPR_RS03755
uniprot id: E4T2H2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

694427:PALPR RS02055
gene id: 694427:PALPR_RS02055
uniprot id: E4T1I0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

694427:PALPR RS12435
gene id: 694427:PALPR_RS12435
uniprot id: E4T7C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

694427:PALPR RS09325
gene id: 694427:PALPR_RS09325
uniprot id: E4T5K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS01365
gene id: 694427:PALPR_RS01365
uniprot id: E4T155
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

694427:PALPR RS12410
gene id: 694427:PALPR_RS12410
uniprot id: E4T7C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

694427:PALPR RS13730
gene id: 694427:PALPR_RS13730
uniprot id: E4T842
names: Similarity
messages: Belongs to the ribF family.

694427:PALPR RS11800
gene id: 694427:PALPR_RS11800
uniprot id: E4T703
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

694427:PALPR RS02450
gene id: 694427:PALPR_RS02450
uniprot id: E4T1Q9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS12370
gene id: 694427:PALPR_RS12370
uniprot id: E4T7B2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

694427:PALPR RS11810
gene id: 694427:PALPR_RS11810
uniprot id: E4T705
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

694427:PALPR RS15405
gene id: 694427:PALPR_RS15405
uniprot id: E4T5F9
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14595
gene id: 694427:PALPR_RS14595
uniprot id: E4T0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS12425
gene id: 694427:PALPR_RS12425
uniprot id: E4T7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS01765
gene id: 694427:PALPR_RS01765
uniprot id: E4T1C2
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

694427:PALPR RS11405
gene id: 694427:PALPR_RS11405
uniprot id: E4T6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

694427:PALPR RS01200
gene id: 694427:PALPR_RS01200
uniprot id: E4T118
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

694427:PALPR RS06450
gene id: 694427:PALPR_RS06450
uniprot id: E4T3Z5
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS14140
gene id: 694427:PALPR_RS14140
uniprot id: E4T8C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

694427:PALPR RS08095
gene id: 694427:PALPR_RS08095
uniprot id: E4T4X0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

694427:PALPR RS08615
gene id: 694427:PALPR_RS08615
uniprot id: E4T568
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

694427:PALPR RS13430
gene id: 694427:PALPR_RS13430
uniprot id: E4T7Y1
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06865
gene id: 694427:PALPR_RS06865
uniprot id: E4T474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

694427:PALPR RS12420
gene id: 694427:PALPR_RS12420
uniprot id: E4T7C3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

694427:PALPR RS03565
gene id: 694427:PALPR_RS03565
uniprot id: E4T2D6
names: Subcellular Location Annotation
messages: Secreted

694427:PALPR RS01645
gene id: 694427:PALPR_RS01645
uniprot id: E4T0A7
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS01105
gene id: 694427:PALPR_RS01105
uniprot id: E4T0Z9
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06095
gene id: 694427:PALPR_RS06095
uniprot id: E4T3S8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

694427:PALPR RS08030
gene id: 694427:PALPR_RS08030
uniprot id: E4T4V8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

694427:PALPR RS12135
gene id: 694427:PALPR_RS12135
uniprot id: E4T766
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

694427:PALPR RS12570
gene id: 694427:PALPR_RS12570
uniprot id: E4T7F3
names: Similarity
messages: Belongs to the peptidase M16 family.

694427:PALPR RS03385
gene id: 694427:PALPR_RS03385
uniprot id: E4T2A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS06640
gene id: 694427:PALPR_RS06640
uniprot id: E4T431
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

694427:PALPR RS06540
gene id: 694427:PALPR_RS06540
uniprot id: E4T411
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

694427:PALPR RS00015
gene id: 694427:PALPR_RS00015
uniprot id: E4T0A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

694427:PALPR RS14530
gene id: 694427:PALPR_RS14530
uniprot id: E4T8K4
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

694427:PALPR RS08320
gene id: 694427:PALPR_RS08320
uniprot id: E4T515
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

694427:PALPR RS13035
gene id: 694427:PALPR_RS13035
uniprot id: E4T7P8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

694427:PALPR RS12465
gene id: 694427:PALPR_RS12465
uniprot id: E4T7D2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

694427:PALPR RS03885
gene id: 694427:PALPR_RS03885
uniprot id: E4T2J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS07740
gene id: 694427:PALPR_RS07740
uniprot id: E4T4Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

694427:PALPR RS14260
gene id: 694427:PALPR_RS14260
uniprot id: E4T8F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS06830
gene id: 694427:PALPR_RS06830
uniprot id: E4T468
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

694427:PALPR RS08895
gene id: 694427:PALPR_RS08895
uniprot id: E4T5C5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS08710
gene id: 694427:PALPR_RS08710
uniprot id: E4T587
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

694427:PALPR RS12205
gene id: 694427:PALPR_RS12205
uniprot id: E4T778
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

694427:PALPR RS02660
gene id: 694427:PALPR_RS02660
uniprot id: E4T1V2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

694427:PALPR RS14800
gene id: 694427:PALPR_RS14800
uniprot id: E4T0N8
names: Similarity
messages: Belongs to the aspartokinase family.

694427:PALPR RS08540
gene id: 694427:PALPR_RS08540
uniprot id: E4T558
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

694427:PALPR RS04575
gene id: 694427:PALPR_RS04575
uniprot id: E4T2Y3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

694427:PALPR RS09320
gene id: 694427:PALPR_RS09320
uniprot id: E4T5K8
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS10775
gene id: 694427:PALPR_RS10775
uniprot id: E4T6E7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

694427:PALPR RS14215
gene id: 694427:PALPR_RS14215
uniprot id: E4T8E1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

694427:PALPR RS05495
gene id: 694427:PALPR_RS05495
uniprot id: E4T3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

694427:PALPR RS12305
gene id: 694427:PALPR_RS12305
uniprot id: E4T799
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

694427:PALPR RS00100
gene id: 694427:PALPR_RS00100
uniprot id: E4T0C5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS10960
gene id: 694427:PALPR_RS10960
uniprot id: E4T6I5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

694427:PALPR RS05760
gene id: 694427:PALPR_RS05760
uniprot id: E4T3L0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

694427:PALPR RS07165
gene id: 694427:PALPR_RS07165
uniprot id: E4T4D3
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

694427:PALPR RS02765
gene id: 694427:PALPR_RS02765
uniprot id: E4T1X4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

694427:PALPR RS07180
gene id: 694427:PALPR_RS07180
uniprot id: E4T4D6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

694427:PALPR RS00685
gene id: 694427:PALPR_RS00685
uniprot id: E4T0E0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

694427:PALPR RS12010
gene id: 694427:PALPR_RS12010
uniprot id: E4T742
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS08550
gene id: 694427:PALPR_RS08550
uniprot id: E4T560
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

694427:PALPR RS05340
gene id: 694427:PALPR_RS05340
uniprot id: E4T3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

694427:PALPR RS06140
gene id: 694427:PALPR_RS06140
uniprot id: E4T3T7
names: Similarity
messages: Belongs to the nitroreductase family.

694427:PALPR RS06475
gene id: 694427:PALPR_RS06475
uniprot id: E4T400
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS12575
gene id: 694427:PALPR_RS12575
uniprot id: E4T7F4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS07275
gene id: 694427:PALPR_RS07275
uniprot id: E4T4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS11015
gene id: 694427:PALPR_RS11015
uniprot id: E4T6J5
names: Similarity
messages: Belongs to the peptidase S66 family.

694427:PALPR RS10685
gene id: 694427:PALPR_RS10685
uniprot id: E4T6C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

694427:PALPR RS04400
gene id: 694427:PALPR_RS04400
uniprot id: E4T2U7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

694427:PALPR RS02960
gene id: 694427:PALPR_RS02960
uniprot id: E4T215
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

694427:PALPR RS07490
gene id: 694427:PALPR_RS07490
uniprot id: E4T4K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

694427:PALPR RS05095
gene id: 694427:PALPR_RS05095
uniprot id: E4T382
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

694427:PALPR RS14120
gene id: 694427:PALPR_RS14120
uniprot id: E4T8C1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

694427:PALPR RS12270
gene id: 694427:PALPR_RS12270
uniprot id: E4T792
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

694427:PALPR RS01430
gene id: 694427:PALPR_RS01430
uniprot id: E4T169
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

694427:PALPR RS03805
gene id: 694427:PALPR_RS03805
uniprot id: E4T2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS09635
gene id: 694427:PALPR_RS09635
uniprot id: E4T5R7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

694427:PALPR RS01655
gene id: 694427:PALPR_RS01655
uniprot id: E4T1A1
names: Similarity
messages: Belongs to the AHA1 family.

694427:PALPR RS01295
gene id: 694427:PALPR_RS01295
uniprot id: E4T138
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

694427:PALPR RS09500
gene id: 694427:PALPR_RS09500
uniprot id: E4T5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

694427:PALPR RS13835
gene id: 694427:PALPR_RS13835
uniprot id: E4T863
names: Similarity
messages: Belongs to the ribulokinase family.

694427:PALPR RS14465
gene id: 694427:PALPR_RS14465
uniprot id: E4T8J2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS00380
gene id: 694427:PALPR_RS00380
uniprot id: E4T0W2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

694427:PALPR RS00655
gene id: 694427:PALPR_RS00655
uniprot id: E4T0D4
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS08345
gene id: 694427:PALPR_RS08345
uniprot id: E4T520
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

694427:PALPR RS12830
gene id: 694427:PALPR_RS12830
uniprot id: E4T7K7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

694427:PALPR RS10040
gene id: 694427:PALPR_RS10040
uniprot id: E4T5Z5
names: Similarity
messages: Belongs to the SusD family.

694427:PALPR RS14105
gene id: 694427:PALPR_RS14105
uniprot id: E4T8B8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

694427:PALPR RS07410
gene id: 694427:PALPR_RS07410
uniprot id: E4T4I4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

694427:PALPR RS06990
gene id: 694427:PALPR_RS06990
uniprot id: E4T499
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

694427:PALPR RS04075
gene id: 694427:PALPR_RS04075
uniprot id: E4T2N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

694427:PALPR RS09285
gene id: 694427:PALPR_RS09285
uniprot id: E4T5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

694427:PALPR RS14135
gene id: 694427:PALPR_RS14135
uniprot id: E4T8C5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

694427:PALPR RS00440
gene id: 694427:PALPR_RS00440
uniprot id: E4T060
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS12350
gene id: 694427:PALPR_RS12350
uniprot id: E4T7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

694427:PALPR RS12720
gene id: 694427:PALPR_RS12720
uniprot id: E4T7I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

694427:PALPR RS13925
gene id: 694427:PALPR_RS13925
uniprot id: E4T883
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS16095
gene id: 694427:PALPR_RS16095
uniprot id: E4T4B5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

694427:PALPR RS07030
gene id: 694427:PALPR_RS07030
uniprot id: E4T4A7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

694427:PALPR RS10305
gene id: 694427:PALPR_RS10305
uniprot id: E4T649
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

694427:PALPR RS12295
gene id: 694427:PALPR_RS12295
uniprot id: E4T797
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

694427:PALPR RS14560
gene id: 694427:PALPR_RS14560
uniprot id: E4T8L0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

694427:PALPR RS00730
gene id: 694427:PALPR_RS00730
uniprot id: E4T0E9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

694427:PALPR RS13705
gene id: 694427:PALPR_RS13705
uniprot id: E4T837
names: Similarity
messages: Belongs to the threonine synthase family.

694427:PALPR RS09600
gene id: 694427:PALPR_RS09600
uniprot id: E4T5R0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

694427:PALPR RS03000
gene id: 694427:PALPR_RS03000
uniprot id: E4T222
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

694427:PALPR RS10320
gene id: 694427:PALPR_RS10320
uniprot id: E4T652
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

694427:PALPR RS06570
gene id: 694427:PALPR_RS06570
uniprot id: E4T417
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS12180
gene id: 694427:PALPR_RS12180
uniprot id: E4T775
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

694427:PALPR RS13280
gene id: 694427:PALPR_RS13280
uniprot id: E4T7V3
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS02185
gene id: 694427:PALPR_RS02185
uniprot id: E4T1K8
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

694427:PALPR RS15220
gene id: 694427:PALPR_RS15220
uniprot id: E4T065
names: Subcellular Location Annotation
messages: Membrane

694427:PALPR RS06050
gene id: 694427:PALPR_RS06050
uniprot id: E4T3R9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

694427:PALPR RS00725
gene id: 694427:PALPR_RS00725
uniprot id: E4T0E8
names: Similarity
messages: Belongs to the Skp family.

694427:PALPR RS04810
gene id: 694427:PALPR_RS04810
uniprot id: E4T328
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

694427:PALPR RS01840
gene id: 694427:PALPR_RS01840
uniprot id: E4T1D7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

694427:PALPR RS12415
gene id: 694427:PALPR_RS12415
uniprot id: E4T7C2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

694427:PALPR RS02065
gene id: 694427:PALPR_RS02065
uniprot id: E4T1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

694427:PALPR RS09360
gene id: 694427:PALPR_RS09360
uniprot id: E4T5L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

694427:PALPR RS09345
gene id: 694427:PALPR_RS09345
uniprot id: E4T5L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

694427:PALPR RS14700
gene id: 694427:PALPR_RS14700
uniprot id: E4T0M0
names: Similarity
messages: Belongs to the HsdR family.

694427:PALPR RS08250
gene id: 694427:PALPR_RS08250
uniprot id: E4T501
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

694427:PALPR RS05165
gene id: 694427:PALPR_RS05165
uniprot id: E4T396
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

694427:PALPR RS08385
gene id: 694427:PALPR_RS08385
uniprot id: E4T529
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

694427:PALPR RS12315
gene id: 694427:PALPR_RS12315
uniprot id: E4T7A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

694427:PALPR RS00625
gene id: 694427:PALPR_RS00625
uniprot id: E4T0C8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS12290
gene id: 694427:PALPR_RS12290
uniprot id: E4T796
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

694427:PALPR RS11055
gene id: 694427:PALPR_RS11055
uniprot id: E4T6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

694427:PALPR RS01675
gene id: 694427:PALPR_RS01675
uniprot id: E4T1A4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

694427:PALPR RS11590
gene id: 694427:PALPR_RS11590
uniprot id: E4T6W1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

694427:PALPR RS04100
gene id: 694427:PALPR_RS04100
uniprot id: E4T2P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

694427:PALPR RS00695
gene id: 694427:PALPR_RS00695
uniprot id: E4T0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

694427:PALPR RS00485
gene id: 694427:PALPR_RS00485
uniprot id: E4T070
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

694427:PALPR RS00030
gene id: 694427:PALPR_RS00030
uniprot id: E4T0B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm