693977:DEIPR RS01380
gene id: 693977:DEIPR_RS01380
uniprot id: F0RJ24
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

693977:DEIPR RS06610
gene id: 693977:DEIPR_RS06610
uniprot id: F0RPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

693977:DEIPR RS10075
gene id: 693977:DEIPR_RS10075
uniprot id: F0RMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

693977:DEIPR RS06410
gene id: 693977:DEIPR_RS06410
uniprot id: F0RP06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

693977:DEIPR RS04350
gene id: 693977:DEIPR_RS04350
uniprot id: F0RM86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

693977:DEIPR RS01930
gene id: 693977:DEIPR_RS01930
uniprot id: F0RJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

693977:DEIPR RS02080
gene id: 693977:DEIPR_RS02080
uniprot id: F0RJU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

693977:DEIPR RS06110
gene id: 693977:DEIPR_RS06110
uniprot id: F0RNU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

693977:DEIPR RS01765
gene id: 693977:DEIPR_RS01765
uniprot id: F0RJG3
names: Similarity
messages: Belongs to the ribF family.

693977:DEIPR RS05550
gene id: 693977:DEIPR_RS05550
uniprot id: F0RNA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

693977:DEIPR RS01625
gene id: 693977:DEIPR_RS01625
uniprot id: F0RJE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

693977:DEIPR RS13215
gene id: 693977:DEIPR_RS13215
uniprot id: F0RR21
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

693977:DEIPR RS02000
gene id: 693977:DEIPR_RS02000
uniprot id: F0RJS7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

693977:DEIPR RS10855
gene id: 693977:DEIPR_RS10855
uniprot id: F0RPG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

693977:DEIPR RS03140
gene id: 693977:DEIPR_RS03140
uniprot id: F0RL03
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

693977:DEIPR RS03590
gene id: 693977:DEIPR_RS03590
uniprot id: F0RLG1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

693977:DEIPR RS03110
gene id: 693977:DEIPR_RS03110
uniprot id: F0RKZ6
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

693977:DEIPR RS09505
gene id: 693977:DEIPR_RS09505
uniprot id: F0RLZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

693977:DEIPR RS03820
gene id: 693977:DEIPR_RS03820
uniprot id: F0RLR4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

693977:DEIPR RS09060
gene id: 693977:DEIPR_RS09060
uniprot id: F0RLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

693977:DEIPR RS00355
gene id: 693977:DEIPR_RS00355
uniprot id: F0RIY0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

693977:DEIPR RS10850
gene id: 693977:DEIPR_RS10850
uniprot id: F0RPG5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

693977:DEIPR RS04495
gene id: 693977:DEIPR_RS04495
uniprot id: F0RMI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

693977:DEIPR RS03735
gene id: 693977:DEIPR_RS03735
uniprot id: F0RLQ4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

693977:DEIPR RS02840
gene id: 693977:DEIPR_RS02840
uniprot id: F0RKM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS10560
gene id: 693977:DEIPR_RS10560
uniprot id: F0RQ12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

693977:DEIPR RS09665
gene id: 693977:DEIPR_RS09665
uniprot id: F0RMA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS05250
gene id: 693977:DEIPR_RS05250
uniprot id: F0RN46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

693977:DEIPR RS05300
gene id: 693977:DEIPR_RS05300
uniprot id: F0RN55
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

693977:DEIPR RS01510
gene id: 693977:DEIPR_RS01510
uniprot id: F0RJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS06340
gene id: 693977:DEIPR_RS06340
uniprot id: F0RNZ3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

693977:DEIPR RS09315
gene id: 693977:DEIPR_RS09315
uniprot id: F0RLV8
names: Similarity
messages: Belongs to the peptidase S8 family.

693977:DEIPR RS04895
gene id: 693977:DEIPR_RS04895
uniprot id: F0RMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

693977:DEIPR RS04470
gene id: 693977:DEIPR_RS04470
uniprot id: F0RMI0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

693977:DEIPR RS09215
gene id: 693977:DEIPR_RS09215
uniprot id: F0RLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

693977:DEIPR RS06675
gene id: 693977:DEIPR_RS06675
uniprot id: F0RPC7
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS07765
gene id: 693977:DEIPR_RS07765
uniprot id: F0RK22
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS08700
gene id: 693977:DEIPR_RS08700
uniprot id: F0RL58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

693977:DEIPR RS05670
gene id: 693977:DEIPR_RS05670
uniprot id: F0RNC8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

693977:DEIPR RS06630
gene id: 693977:DEIPR_RS06630
uniprot id: F0RPB8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

693977:DEIPR RS11250
gene id: 693977:DEIPR_RS11250
uniprot id: F0RPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

693977:DEIPR RS05840
gene id: 693977:DEIPR_RS05840
uniprot id: F0RNH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

693977:DEIPR RS02970
gene id: 693977:DEIPR_RS02970
uniprot id: F0RKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

693977:DEIPR RS09230
gene id: 693977:DEIPR_RS09230
uniprot id: F0RLM7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

693977:DEIPR RS04830
gene id: 693977:DEIPR_RS04830
uniprot id: F0RMW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

693977:DEIPR RS12260
gene id: 693977:DEIPR_RS12260
uniprot id: F0RQI6
names: Similarity
messages: Belongs to the SCO1/2 family.

693977:DEIPR RS08020
gene id: 693977:DEIPR_RS08020
uniprot id: F0RKD8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

693977:DEIPR RS02195
gene id: 693977:DEIPR_RS02195
uniprot id: F0RJW7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

693977:DEIPR RS06665
gene id: 693977:DEIPR_RS06665
uniprot id: F0RPC5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

693977:DEIPR RS08260
gene id: 693977:DEIPR_RS08260
uniprot id: F0RKQ4
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS05810
gene id: 693977:DEIPR_RS05810
uniprot id: F0RNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

693977:DEIPR RS04595
gene id: 693977:DEIPR_RS04595
uniprot id: F0RMK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

693977:DEIPR RS09560
gene id: 693977:DEIPR_RS09560
uniprot id: F0RM05
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

693977:DEIPR RS10405
gene id: 693977:DEIPR_RS10405
uniprot id: F0RPY1
names: Similarity
messages: Belongs to the WrbA family.

693977:DEIPR RS02625
gene id: 693977:DEIPR_RS02625
uniprot id: F0RKI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

693977:DEIPR RS13185
gene id: 693977:DEIPR_RS13185
uniprot id: F0RR15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

693977:DEIPR RS09285
gene id: 693977:DEIPR_RS09285
uniprot id: F0RLV2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

693977:DEIPR RS08750
gene id: 693977:DEIPR_RS08750
uniprot id: F0RL69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

693977:DEIPR RS08995
gene id: 693977:DEIPR_RS08995
uniprot id: F0RLI2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

693977:DEIPR RS05565
gene id: 693977:DEIPR_RS05565
uniprot id: F0RNA7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

693977:DEIPR RS08160
gene id: 693977:DEIPR_RS08160
uniprot id: F0RKG7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

693977:DEIPR RS04705
gene id: 693977:DEIPR_RS04705
uniprot id: F0RMT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

693977:DEIPR RS10465
gene id: 693977:DEIPR_RS10465
uniprot id: F0RPZ3
names: Similarity
messages: Belongs to the FemABX family.

693977:DEIPR RS00030
gene id: 693977:DEIPR_RS00030
uniprot id: F0RIS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS06385
gene id: 693977:DEIPR_RS06385
uniprot id: F0RP01
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

693977:DEIPR RS05970
gene id: 693977:DEIPR_RS05970
uniprot id: F0RNK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

693977:DEIPR RS10290
gene id: 693977:DEIPR_RS10290
uniprot id: F0RPV7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

693977:DEIPR RS07460
gene id: 693977:DEIPR_RS07460
uniprot id: F0RJP5
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS02600
gene id: 693977:DEIPR_RS02600
uniprot id: F0RKI1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS00125
gene id: 693977:DEIPR_RS00125
uniprot id: F0RIU4
names: Similarity
messages: Belongs to the SufE family.

693977:DEIPR RS03520
gene id: 693977:DEIPR_RS03520
uniprot id: F0RLE8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

693977:DEIPR RS04405
gene id: 693977:DEIPR_RS04405
uniprot id: F0RMG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

693977:DEIPR RS07815
gene id: 693977:DEIPR_RS07815
uniprot id: F0RK32
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

693977:DEIPR RS01370
gene id: 693977:DEIPR_RS01370
uniprot id: F0RJ21
names: Similarity
messages: Belongs to the GARS family.

693977:DEIPR RS04420
gene id: 693977:DEIPR_RS04420
uniprot id: F0RMH0
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

693977:DEIPR RS05355
gene id: 693977:DEIPR_RS05355
uniprot id: F0RN67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

693977:DEIPR RS06890
gene id: 693977:DEIPR_RS06890
uniprot id: F0RJ75
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

693977:DEIPR RS00790
gene id: 693977:DEIPR_RS00790
uniprot id: F0RNT7
names: Similarity
messages: Belongs to the peptidase S33 family.

693977:DEIPR RS09025
gene id: 693977:DEIPR_RS09025
uniprot id: F0RLI8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS11340
gene id: 693977:DEIPR_RS11340
uniprot id: F0RPQ9
names: Similarity
messages: Belongs to the peptidase S8 family.

693977:DEIPR RS08350
gene id: 693977:DEIPR_RS08350
uniprot id: F0RKS2
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS12810
gene id: 693977:DEIPR_RS12810
uniprot id: F0RQU2
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS06210
gene id: 693977:DEIPR_RS06210
uniprot id: F0RNW8
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS09725
gene id: 693977:DEIPR_RS09725
uniprot id: F0RMA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

693977:DEIPR RS03225
gene id: 693977:DEIPR_RS03225
uniprot id: F0RL19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS11825
gene id: 693977:DEIPR_RS11825
uniprot id: F0RQA6
names: Similarity
messages: Belongs to the ParB family.

693977:DEIPR RS07660
gene id: 693977:DEIPR_RS07660
uniprot id: F0RK02
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

693977:DEIPR RS02250
gene id: 693977:DEIPR_RS02250
uniprot id: F0RK45
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

693977:DEIPR RS08905
gene id: 693977:DEIPR_RS08905
uniprot id: F0RLA0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

693977:DEIPR RS12240
gene id: 693977:DEIPR_RS12240
uniprot id: F0RQI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

693977:DEIPR RS01935
gene id: 693977:DEIPR_RS01935
uniprot id: F0RJR4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS02335
gene id: 693977:DEIPR_RS02335
uniprot id: F0RK61
names: Similarity
messages: Belongs to the RutC family.

693977:DEIPR RS05140
gene id: 693977:DEIPR_RS05140
uniprot id: F0RN24
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

693977:DEIPR RS09330
gene id: 693977:DEIPR_RS09330
uniprot id: F0RLW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

693977:DEIPR RS01665
gene id: 693977:DEIPR_RS01665
uniprot id: F0RJE8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

693977:DEIPR RS00540
gene id: 693977:DEIPR_RS00540
uniprot id: F0RNP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

693977:DEIPR RS09790
gene id: 693977:DEIPR_RS09790
uniprot id: F0RMC2
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

693977:DEIPR RS01825
gene id: 693977:DEIPR_RS01825
uniprot id: F0RJH7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

693977:DEIPR RS07675
gene id: 693977:DEIPR_RS07675
uniprot id: F0RK05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS07650
gene id: 693977:DEIPR_RS07650
uniprot id: F0RK00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS06480
gene id: 693977:DEIPR_RS06480
uniprot id: F0RP88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

693977:DEIPR RS11755
gene id: 693977:DEIPR_RS11755
uniprot id: F0RQ93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

693977:DEIPR RS04115
gene id: 693977:DEIPR_RS04115
uniprot id: F0RM39
names: Similarity
messages: Belongs to the type IB topoisomerase family.

693977:DEIPR RS04490
gene id: 693977:DEIPR_RS04490
uniprot id: F0RMI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

693977:DEIPR RS06305
gene id: 693977:DEIPR_RS06305
uniprot id: F0RNY7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

693977:DEIPR RS07200
gene id: 693977:DEIPR_RS07200
uniprot id: F0RJJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS02025
gene id: 693977:DEIPR_RS02025
uniprot id: F0RJT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

693977:DEIPR RS10040
gene id: 693977:DEIPR_RS10040
uniprot id: F0RMP1
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

693977:DEIPR RS13605
gene id: 693977:DEIPR_RS13605
uniprot id: F0RR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

693977:DEIPR RS10600
gene id: 693977:DEIPR_RS10600
uniprot id: F0RQ20
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS10110
gene id: 693977:DEIPR_RS10110
uniprot id: F0RMQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

693977:DEIPR RS05735
gene id: 693977:DEIPR_RS05735
uniprot id: F0RNE1
names: Similarity
messages: Belongs to the cytochrome P450 family.

693977:DEIPR RS08100
gene id: 693977:DEIPR_RS08100
uniprot id: F0RKF4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

693977:DEIPR RS01345
gene id: 693977:DEIPR_RS01345
uniprot id: F0RJ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS01235
gene id: 693977:DEIPR_RS01235
uniprot id: F0RIZ4
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

693977:DEIPR RS04650
gene id: 693977:DEIPR_RS04650
uniprot id: F0RML7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

693977:DEIPR RS04320
gene id: 693977:DEIPR_RS04320
uniprot id: F0RM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

693977:DEIPR RS10530
gene id: 693977:DEIPR_RS10530
uniprot id: F0RQ06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

693977:DEIPR RS09065
gene id: 693977:DEIPR_RS09065
uniprot id: F0RLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

693977:DEIPR RS02015
gene id: 693977:DEIPR_RS02015
uniprot id: F0RJT0
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS10720
gene id: 693977:DEIPR_RS10720
uniprot id: F0RQ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

693977:DEIPR RS02010
gene id: 693977:DEIPR_RS02010
uniprot id: F0RJS9
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS12245
gene id: 693977:DEIPR_RS12245
uniprot id: F0RQI3
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS11190
gene id: 693977:DEIPR_RS11190
uniprot id: F0RPN1
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS04610
gene id: 693977:DEIPR_RS04610
uniprot id: F0RMK9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

693977:DEIPR RS04500
gene id: 693977:DEIPR_RS04500
uniprot id: F0RMI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

693977:DEIPR RS10945
gene id: 693977:DEIPR_RS10945
uniprot id: F0RPI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS05275
gene id: 693977:DEIPR_RS05275
uniprot id: F0RN50
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

693977:DEIPR RS05890
gene id: 693977:DEIPR_RS05890
uniprot id: F0RNI8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

693977:DEIPR RS08060
gene id: 693977:DEIPR_RS08060
uniprot id: F0RKE6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

693977:DEIPR RS08010
gene id: 693977:DEIPR_RS08010
uniprot id: F0RKD6
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS11185
gene id: 693977:DEIPR_RS11185
uniprot id: F0RPN0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

693977:DEIPR RS07640
gene id: 693977:DEIPR_RS07640
uniprot id: F0RJZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS05760
gene id: 693977:DEIPR_RS05760
uniprot id: F0RNG2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

693977:DEIPR RS09885
gene id: 693977:DEIPR_RS09885
uniprot id: F0RME1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

693977:DEIPR RS07295
gene id: 693977:DEIPR_RS07295
uniprot id: F0RJL4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

693977:DEIPR RS01725
gene id: 693977:DEIPR_RS01725
uniprot id: F0RJF8
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

693977:DEIPR RS04835
gene id: 693977:DEIPR_RS04835
uniprot id: F0RMW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS05785
gene id: 693977:DEIPR_RS05785
uniprot id: F0RNG7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

693977:DEIPR RS02505
gene id: 693977:DEIPR_RS02505
uniprot id: F0RK94
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS04880
gene id: 693977:DEIPR_RS04880
uniprot id: F0RMX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS07110
gene id: 693977:DEIPR_RS07110
uniprot id: F0RJB4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

693977:DEIPR RS05620
gene id: 693977:DEIPR_RS05620
uniprot id: F0RNB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS02790
gene id: 693977:DEIPR_RS02790
uniprot id: F0RKL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

693977:DEIPR RS05995
gene id: 693977:DEIPR_RS05995
uniprot id: F0RNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

693977:DEIPR RS09925
gene id: 693977:DEIPR_RS09925
uniprot id: F0RME9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

693977:DEIPR RS02620
gene id: 693977:DEIPR_RS02620
uniprot id: F0RKI5
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS06295
gene id: 693977:DEIPR_RS06295
uniprot id: F0RNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

693977:DEIPR RS09490
gene id: 693977:DEIPR_RS09490
uniprot id: F0RLZ3
names: Similarity
messages: Belongs to the XseB family.

693977:DEIPR RS06590
gene id: 693977:DEIPR_RS06590
uniprot id: F0RPB0
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

693977:DEIPR RS02240
gene id: 693977:DEIPR_RS02240
uniprot id: F0RK43
names: Similarity
messages: Belongs to the citrate synthase family.

693977:DEIPR RS05155
gene id: 693977:DEIPR_RS05155
uniprot id: F0RN27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

693977:DEIPR RS02020
gene id: 693977:DEIPR_RS02020
uniprot id: F0RJT1
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS10735
gene id: 693977:DEIPR_RS10735
uniprot id: F0RQ46
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

693977:DEIPR RS11220
gene id: 693977:DEIPR_RS11220
uniprot id: F0RPN6
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

693977:DEIPR RS05820
gene id: 693977:DEIPR_RS05820
uniprot id: F0RNH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

693977:DEIPR RS13265
gene id: 693977:DEIPR_RS13265
uniprot id: F0RR30
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

693977:DEIPR RS06180
gene id: 693977:DEIPR_RS06180
uniprot id: F0RNW2
names: Similarity
messages: Belongs to the cytochrome P450 family.

693977:DEIPR RS02835
gene id: 693977:DEIPR_RS02835
uniprot id: F0RKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

693977:DEIPR RS01865
gene id: 693977:DEIPR_RS01865
uniprot id: F0RJI5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

693977:DEIPR RS05635
gene id: 693977:DEIPR_RS05635
uniprot id: F0RNC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

693977:DEIPR RS10645
gene id: 693977:DEIPR_RS10645
uniprot id: F0RQ28
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

693977:DEIPR RS01910
gene id: 693977:DEIPR_RS01910
uniprot id: F0RJQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

693977:DEIPR RS04990
gene id: 693977:DEIPR_RS04990
uniprot id: F0RMZ4
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

693977:DEIPR RS07320
gene id: 693977:DEIPR_RS07320
uniprot id: F0RJL9
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

693977:DEIPR RS06535
gene id: 693977:DEIPR_RS06535
uniprot id: F0RP99
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS07115
gene id: 693977:DEIPR_RS07115
uniprot id: F0RJB5
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

693977:DEIPR RS07330
gene id: 693977:DEIPR_RS07330
uniprot id: F0RJM1
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS03695
gene id: 693977:DEIPR_RS03695
uniprot id: F0RLP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS05625
gene id: 693977:DEIPR_RS05625
uniprot id: F0RNB9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS08075
gene id: 693977:DEIPR_RS08075
uniprot id: F0RKE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

693977:DEIPR RS10280
gene id: 693977:DEIPR_RS10280
uniprot id: F0RPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

693977:DEIPR RS10010
gene id: 693977:DEIPR_RS10010
uniprot id: F0RMN5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

693977:DEIPR RS10565
gene id: 693977:DEIPR_RS10565
uniprot id: F0RQ13
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

693977:DEIPR RS00305
gene id: 693977:DEIPR_RS00305
uniprot id: F0RIX0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

693977:DEIPR RS10130
gene id: 693977:DEIPR_RS10130
uniprot id: F0RMQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

693977:DEIPR RS00705
gene id: 693977:DEIPR_RS00705
uniprot id: F0RNS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

693977:DEIPR RS01430
gene id: 693977:DEIPR_RS01430
uniprot id: F0RJ34
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

693977:DEIPR RS06625
gene id: 693977:DEIPR_RS06625
uniprot id: F0RPB7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

693977:DEIPR RS03490
gene id: 693977:DEIPR_RS03490
uniprot id: F0RLE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

693977:DEIPR RS10225
gene id: 693977:DEIPR_RS10225
uniprot id: F0RMS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

693977:DEIPR RS00810
gene id: 693977:DEIPR_RS00810
uniprot id: F0RNU1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

693977:DEIPR RS07405
gene id: 693977:DEIPR_RS07405
uniprot id: F0RJN5
names: Similarity
messages: Belongs to the RutC family.

693977:DEIPR RS10215
gene id: 693977:DEIPR_RS10215
uniprot id: F0RMS6
names: Similarity
messages: Belongs to the glutamate synthase family.

693977:DEIPR RS03770
gene id: 693977:DEIPR_RS03770
uniprot id: F0RLR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

693977:DEIPR RS06780
gene id: 693977:DEIPR_RS06780
uniprot id: F0RJ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

693977:DEIPR RS06260
gene id: 693977:DEIPR_RS06260
uniprot id: F0RNX8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

693977:DEIPR RS05060
gene id: 693977:DEIPR_RS05060
uniprot id: F0RN08
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

693977:DEIPR RS08475
gene id: 693977:DEIPR_RS08475
uniprot id: F0RKU3
names: Similarity
messages: Belongs to the peptidase C40 family.

693977:DEIPR RS10165
gene id: 693977:DEIPR_RS10165
uniprot id: F0RMR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

693977:DEIPR RS12760
gene id: 693977:DEIPR_RS12760
uniprot id: F0RQT2
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS09165
gene id: 693977:DEIPR_RS09165
uniprot id: F0RLL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

693977:DEIPR RS05860
gene id: 693977:DEIPR_RS05860
uniprot id: F0RNI2
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS01570
gene id: 693977:DEIPR_RS01570
uniprot id: F0RJC9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

693977:DEIPR RS03120
gene id: 693977:DEIPR_RS03120
uniprot id: F0RKZ8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

693977:DEIPR RS04255
gene id: 693977:DEIPR_RS04255
uniprot id: F0RM67
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS09880
gene id: 693977:DEIPR_RS09880
uniprot id: F0RME0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

693977:DEIPR RS09275
gene id: 693977:DEIPR_RS09275
uniprot id: F0RLV0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

693977:DEIPR RS03355
gene id: 693977:DEIPR_RS03355
uniprot id: F0RLB4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

693977:DEIPR RS08035
gene id: 693977:DEIPR_RS08035
uniprot id: F0RKE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

693977:DEIPR RS03575
gene id: 693977:DEIPR_RS03575
uniprot id: F0RLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

693977:DEIPR RS09255
gene id: 693977:DEIPR_RS09255
uniprot id: F0RLN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

693977:DEIPR RS00555
gene id: 693977:DEIPR_RS00555
uniprot id: F0RNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

693977:DEIPR RS05645
gene id: 693977:DEIPR_RS05645
uniprot id: F0RNC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS00175
gene id: 693977:DEIPR_RS00175
uniprot id: F0RIV3
names: Similarity
messages: Belongs to the peptidase M16 family.

693977:DEIPR RS09740
gene id: 693977:DEIPR_RS09740
uniprot id: F0RMB2
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

693977:DEIPR RS04775
gene id: 693977:DEIPR_RS04775
uniprot id: F0RMV1
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

693977:DEIPR RS09500
gene id: 693977:DEIPR_RS09500
uniprot id: F0RLZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS07505
gene id: 693977:DEIPR_RS07505
uniprot id: F0RJX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

693977:DEIPR RS07990
gene id: 693977:DEIPR_RS07990
uniprot id: F0RKD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS03065
gene id: 693977:DEIPR_RS03065
uniprot id: F0RKY7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

693977:DEIPR RS10870
gene id: 693977:DEIPR_RS10870
uniprot id: F0RPG9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

693977:DEIPR RS02310
gene id: 693977:DEIPR_RS02310
uniprot id: F0RK56
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

693977:DEIPR RS00380
gene id: 693977:DEIPR_RS00380
uniprot id: F0RNE2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

693977:DEIPR RS02190
gene id: 693977:DEIPR_RS02190
uniprot id: F0RJW6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

693977:DEIPR RS03920
gene id: 693977:DEIPR_RS03920
uniprot id: F0RLT5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

693977:DEIPR RS06895
gene id: 693977:DEIPR_RS06895
uniprot id: F0RJ76
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

693977:DEIPR RS01925
gene id: 693977:DEIPR_RS01925
uniprot id: F0RJR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

693977:DEIPR RS00290
gene id: 693977:DEIPR_RS00290
uniprot id: F0RIW7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

693977:DEIPR RS12380
gene id: 693977:DEIPR_RS12380
uniprot id: F0RQK8
names: Similarity
messages: Belongs to the GSP E family.

693977:DEIPR RS02910
gene id: 693977:DEIPR_RS02910
uniprot id: F0RKN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS06940
gene id: 693977:DEIPR_RS06940
uniprot id: F0RJ85
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

693977:DEIPR RS06395
gene id: 693977:DEIPR_RS06395
uniprot id: F0RP03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

693977:DEIPR RS01945
gene id: 693977:DEIPR_RS01945
uniprot id: F0RJR6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

693977:DEIPR RS02490
gene id: 693977:DEIPR_RS02490
uniprot id: F0RK91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

693977:DEIPR RS08270
gene id: 693977:DEIPR_RS08270
uniprot id: F0RKQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

693977:DEIPR RS11240
gene id: 693977:DEIPR_RS11240
uniprot id: F0RPP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

693977:DEIPR RS09675
gene id: 693977:DEIPR_RS09675
uniprot id: F0RMA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

693977:DEIPR RS08490
gene id: 693977:DEIPR_RS08490
uniprot id: F0RKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

693977:DEIPR RS09920
gene id: 693977:DEIPR_RS09920
uniprot id: F0RME8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

693977:DEIPR RS04760
gene id: 693977:DEIPR_RS04760
uniprot id: F0RMU8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

693977:DEIPR RS02055
gene id: 693977:DEIPR_RS02055
uniprot id: F0RJT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

693977:DEIPR RS09640
gene id: 693977:DEIPR_RS09640
uniprot id: F0RM95
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS07010
gene id: 693977:DEIPR_RS07010
uniprot id: F0RJ97
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

693977:DEIPR RS03460
gene id: 693977:DEIPR_RS03460
uniprot id: F0RLD6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

693977:DEIPR RS00980
gene id: 693977:DEIPR_RS00980
uniprot id: F0RP34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

693977:DEIPR RS10630
gene id: 693977:DEIPR_RS10630
uniprot id: F0RQ25
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

693977:DEIPR RS11400
gene id: 693977:DEIPR_RS11400
uniprot id: F0RPS1
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS10015
gene id: 693977:DEIPR_RS10015
uniprot id: F0RMN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MnmG family.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

693977:DEIPR RS04825
gene id: 693977:DEIPR_RS04825
uniprot id: F0RMW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

693977:DEIPR RS02115
gene id: 693977:DEIPR_RS02115
uniprot id: F0RJV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

693977:DEIPR RS04755
gene id: 693977:DEIPR_RS04755
uniprot id: F0RMU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

693977:DEIPR RS05165
gene id: 693977:DEIPR_RS05165
uniprot id: F0RN29
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS10030
gene id: 693977:DEIPR_RS10030
uniprot id: F0RMN9
names: Similarity
messages: Belongs to the ParB family.

693977:DEIPR RS11305
gene id: 693977:DEIPR_RS11305
uniprot id: F0RPQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

693977:DEIPR RS00560
gene id: 693977:DEIPR_RS00560
uniprot id: F0RNP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS10445
gene id: 693977:DEIPR_RS10445
uniprot id: F0RPY9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

693977:DEIPR RS11255
gene id: 693977:DEIPR_RS11255
uniprot id: F0RPP3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

693977:DEIPR RS06700
gene id: 693977:DEIPR_RS06700
uniprot id: F0RPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

693977:DEIPR RS05500
gene id: 693977:DEIPR_RS05500
uniprot id: F0RN94
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

693977:DEIPR RS02630
gene id: 693977:DEIPR_RS02630
uniprot id: F0RKI7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

693977:DEIPR RS01720
gene id: 693977:DEIPR_RS01720
uniprot id: F0RJF7
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

693977:DEIPR RS11545
gene id: 693977:DEIPR_RS11545
uniprot id: F0RPV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

693977:DEIPR RS07895
gene id: 693977:DEIPR_RS07895
uniprot id: F0RKB3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

693977:DEIPR RS03625
gene id: 693977:DEIPR_RS03625
uniprot id: F0RLG8
names: Similarity
messages: Belongs to the PGI/PMI family.

693977:DEIPR RS01490
gene id: 693977:DEIPR_RS01490
uniprot id: F0RJ46
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS11130
gene id: 693977:DEIPR_RS11130
uniprot id: F0RPM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

693977:DEIPR RS04355
gene id: 693977:DEIPR_RS04355
uniprot id: F0RM87
names: Similarity
messages: Belongs to the glutamine synthetase family.

693977:DEIPR RS06220
gene id: 693977:DEIPR_RS06220
uniprot id: F0RNX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS02760
gene id: 693977:DEIPR_RS02760
uniprot id: F0RKL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

693977:DEIPR RS09115
gene id: 693977:DEIPR_RS09115
uniprot id: F0RLK6
names: Similarity
messages: Belongs to the fabD family.

693977:DEIPR RS10555
gene id: 693977:DEIPR_RS10555
uniprot id: F0RQ11
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

693977:DEIPR RS01985
gene id: 693977:DEIPR_RS01985
uniprot id: F0RJS4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

693977:DEIPR RS10655
gene id: 693977:DEIPR_RS10655
uniprot id: F0RQ30
names: Similarity
messages: Belongs to the manganese catalase family.

693977:DEIPR RS13080
gene id: 693977:DEIPR_RS13080
uniprot id: F0RQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

693977:DEIPR RS00830
gene id: 693977:DEIPR_RS00830
uniprot id: F0RP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

693977:DEIPR RS13415
gene id: 693977:DEIPR_RS13415
uniprot id: F0RR57
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

693977:DEIPR RS11320
gene id: 693977:DEIPR_RS11320
uniprot id: F0RPQ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS09670
gene id: 693977:DEIPR_RS09670
uniprot id: P94695
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock (By similarity).

693977:DEIPR RS10535
gene id: 693977:DEIPR_RS10535
uniprot id: F0RQ07
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

693977:DEIPR RS07280
gene id: 693977:DEIPR_RS07280
uniprot id: F0RJL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

693977:DEIPR RS04520
gene id: 693977:DEIPR_RS04520
uniprot id: F0RMJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

693977:DEIPR RS04175
gene id: 693977:DEIPR_RS04175
uniprot id: F0RM51
names: Similarity
messages: Belongs to the OsmC/Ohr family.

693977:DEIPR RS02065
gene id: 693977:DEIPR_RS02065
uniprot id: F0RJU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

693977:DEIPR RS01055
gene id: 693977:DEIPR_RS01055
uniprot id: F0RP49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

693977:DEIPR RS00395
gene id: 693977:DEIPR_RS00395
uniprot id: F0RNE5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

693977:DEIPR RS03565
gene id: 693977:DEIPR_RS03565
uniprot id: F0RLF6
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS06040
gene id: 693977:DEIPR_RS06040
uniprot id: F0RNL8
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS02810
gene id: 693977:DEIPR_RS02810
uniprot id: F0RKL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

693977:DEIPR RS11100
gene id: 693977:DEIPR_RS11100
uniprot id: F0RPL4
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

693977:DEIPR RS01420
gene id: 693977:DEIPR_RS01420
uniprot id: F0RJ32
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

693977:DEIPR RS04130
gene id: 693977:DEIPR_RS04130
uniprot id: F0RM42
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

693977:DEIPR RS10995
gene id: 693977:DEIPR_RS10995
uniprot id: F0RPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS11775
gene id: 693977:DEIPR_RS11775
uniprot id: F0RQ97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS03585
gene id: 693977:DEIPR_RS03585
uniprot id: F0RLG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

693977:DEIPR RS05780
gene id: 693977:DEIPR_RS05780
uniprot id: F0RNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

693977:DEIPR RS02160
gene id: 693977:DEIPR_RS02160
uniprot id: F0RJV9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

693977:DEIPR RS08040
gene id: 693977:DEIPR_RS08040
uniprot id: F0RKE2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

693977:DEIPR RS05325
gene id: 693977:DEIPR_RS05325
uniprot id: F0RN59
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

693977:DEIPR RS10160
gene id: 693977:DEIPR_RS10160
uniprot id: F0RMR5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

693977:DEIPR RS08470
gene id: 693977:DEIPR_RS08470
uniprot id: F0RKU2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

693977:DEIPR RS12855
gene id: 693977:DEIPR_RS12855
uniprot id: F0RQV1
names: Caution
names: Cofactor
names: Domain
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS09540
gene id: 693977:DEIPR_RS09540
uniprot id: F0RM01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS05050
gene id: 693977:DEIPR_RS05050
uniprot id: F0RN06
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

693977:DEIPR RS01530
gene id: 693977:DEIPR_RS01530
uniprot id: F0RJC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

693977:DEIPR RS08835
gene id: 693977:DEIPR_RS08835
uniprot id: F0RL86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

693977:DEIPR RS06635
gene id: 693977:DEIPR_RS06635
uniprot id: F0RPB9
names: Similarity
messages: Belongs to the GSP E family.

693977:DEIPR RS08675
gene id: 693977:DEIPR_RS08675
uniprot id: F0RL53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

693977:DEIPR RS02075
gene id: 693977:DEIPR_RS02075
uniprot id: F0RJU2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

693977:DEIPR RS09575
gene id: 693977:DEIPR_RS09575
uniprot id: F0RM09
names: Subcellular Location Annotation
messages: Nucleus

693977:DEIPR RS12165
gene id: 693977:DEIPR_RS12165
uniprot id: F0RQH5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

693977:DEIPR RS02350
gene id: 693977:DEIPR_RS02350
uniprot id: F0RK64
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

693977:DEIPR RS12255
gene id: 693977:DEIPR_RS12255
uniprot id: F0RQI5
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS07070
gene id: 693977:DEIPR_RS07070
uniprot id: F0RJA8
names: Similarity
messages: Belongs to the acylphosphatase family.

693977:DEIPR RS00430
gene id: 693977:DEIPR_RS00430
uniprot id: F0RNF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

693977:DEIPR RS04710
gene id: 693977:DEIPR_RS04710
uniprot id: F0RMT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS03555
gene id: 693977:DEIPR_RS03555
uniprot id: F0RLF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

693977:DEIPR RS08540
gene id: 693977:DEIPR_RS08540
uniprot id: F0RKV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

693977:DEIPR RS07195
gene id: 693977:DEIPR_RS07195
uniprot id: F0RJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS06650
gene id: 693977:DEIPR_RS06650
uniprot id: F0RPC2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

693977:DEIPR RS06035
gene id: 693977:DEIPR_RS06035
uniprot id: F0RNL7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS04745
gene id: 693977:DEIPR_RS04745
uniprot id: F0RMU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

693977:DEIPR RS00970
gene id: 693977:DEIPR_RS00970
uniprot id: F0RP32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

693977:DEIPR RS11405
gene id: 693977:DEIPR_RS11405
uniprot id: F0RPS2
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS01995
gene id: 693977:DEIPR_RS01995
uniprot id: F0RJS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

693977:DEIPR RS14555
gene id: 693977:DEIPR_RS14555
uniprot id: F0RMV8
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS09390
gene id: 693977:DEIPR_RS09390
uniprot id: F0RLX3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

693977:DEIPR RS03650
gene id: 693977:DEIPR_RS03650
uniprot id: F0RLN7
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS04225
gene id: 693977:DEIPR_RS04225
uniprot id: F0RM61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

693977:DEIPR RS10515
gene id: 693977:DEIPR_RS10515
uniprot id: F0RQ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

693977:DEIPR RS03710
gene id: 693977:DEIPR_RS03710
uniprot id: F0RLP8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

693977:DEIPR RS00400
gene id: 693977:DEIPR_RS00400
uniprot id: F0RNE6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

693977:DEIPR RS11365
gene id: 693977:DEIPR_RS11365
uniprot id: F0RPR4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

693977:DEIPR RS07220
gene id: 693977:DEIPR_RS07220
uniprot id: F0RJK2
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

693977:DEIPR RS05295
gene id: 693977:DEIPR_RS05295
uniprot id: F0RN54
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS08495
gene id: 693977:DEIPR_RS08495
uniprot id: F0RKU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

693977:DEIPR RS04000
gene id: 693977:DEIPR_RS04000
uniprot id: F0RLU7
names: Similarity
messages: Belongs to the peptidase S8 family.

693977:DEIPR RS00925
gene id: 693977:DEIPR_RS00925
uniprot id: F0RP25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

693977:DEIPR RS01655
gene id: 693977:DEIPR_RS01655
uniprot id: F0RJE6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

693977:DEIPR RS11495
gene id: 693977:DEIPR_RS11495
uniprot id: F0RPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS03180
gene id: 693977:DEIPR_RS03180
uniprot id: F0RL10
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

693977:DEIPR RS01955
gene id: 693977:DEIPR_RS01955
uniprot id: F0RJR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

693977:DEIPR RS04440
gene id: 693977:DEIPR_RS04440
uniprot id: F0RMH4
names: Subcellular Location Annotation
messages: Cytoplasm

693977:DEIPR RS10410
gene id: 693977:DEIPR_RS10410
uniprot id: F0RPY2
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

693977:DEIPR RS00870
gene id: 693977:DEIPR_RS00870
uniprot id: F0RP19
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS04855
gene id: 693977:DEIPR_RS04855
uniprot id: F0RMW7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

693977:DEIPR RS04980
gene id: 693977:DEIPR_RS04980
uniprot id: F0RMZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

693977:DEIPR RS05025
gene id: 693977:DEIPR_RS05025
uniprot id: F0RN01
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

693977:DEIPR RS10770
gene id: 693977:DEIPR_RS10770
uniprot id: F0RPE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

693977:DEIPR RS06835
gene id: 693977:DEIPR_RS06835
uniprot id: F0RJ64
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

693977:DEIPR RS00015
gene id: 693977:DEIPR_RS00015
uniprot id: F0RIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

693977:DEIPR RS08215
gene id: 693977:DEIPR_RS08215
uniprot id: F0RKH7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

693977:DEIPR RS10685
gene id: 693977:DEIPR_RS10685
uniprot id: F0RQ36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS11045
gene id: 693977:DEIPR_RS11045
uniprot id: F0RPK3
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS00940
gene id: 693977:DEIPR_RS00940
uniprot id: F0RP26
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS02660
gene id: 693977:DEIPR_RS02660
uniprot id: F0RKJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

693977:DEIPR RS06885
gene id: 693977:DEIPR_RS06885
uniprot id: F0RJ74
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

693977:DEIPR RS12860
gene id: 693977:DEIPR_RS12860
uniprot id: F0RQV2
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS00245
gene id: 693977:DEIPR_RS00245
uniprot id: F0RIW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

693977:DEIPR RS09000
gene id: 693977:DEIPR_RS09000
uniprot id: F0RLI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

693977:DEIPR RS00840
gene id: 693977:DEIPR_RS00840
uniprot id: F0RP14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

693977:DEIPR RS02775
gene id: 693977:DEIPR_RS02775
uniprot id: F0RKL2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

693977:DEIPR RS09035
gene id: 693977:DEIPR_RS09035
uniprot id: F0RLJ0
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

693977:DEIPR RS03015
gene id: 693977:DEIPR_RS03015
uniprot id: F0RKX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

693977:DEIPR RS02200
gene id: 693977:DEIPR_RS02200
uniprot id: F0RJW8
names: Similarity
messages: Belongs to the thioredoxin family.

693977:DEIPR RS02540
gene id: 693977:DEIPR_RS02540
uniprot id: F0RKA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

693977:DEIPR RS03925
gene id: 693977:DEIPR_RS03925
uniprot id: F0RLT6
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS02475
gene id: 693977:DEIPR_RS02475
uniprot id: F0RK88
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS12400
gene id: 693977:DEIPR_RS12400
uniprot id: F0RQL2
names: Similarity
messages: Belongs to the bacterial secretin family.

693977:DEIPR RS06750
gene id: 693977:DEIPR_RS06750
uniprot id: F0RPE2
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS04395
gene id: 693977:DEIPR_RS04395
uniprot id: F0RMG5
names: Similarity
messages: Belongs to the peptidase M29 family.

693977:DEIPR RS04190
gene id: 693977:DEIPR_RS04190
uniprot id: F0RM54
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS10755
gene id: 693977:DEIPR_RS10755
uniprot id: F0RPE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

693977:DEIPR RS07275
gene id: 693977:DEIPR_RS07275
uniprot id: F0RJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

693977:DEIPR RS09455
gene id: 693977:DEIPR_RS09455
uniprot id: F0RLY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

693977:DEIPR RS07020
gene id: 693977:DEIPR_RS07020
uniprot id: F0RJ98
names: Similarity
messages: Belongs to the ycf81 family.

693977:DEIPR RS05850
gene id: 693977:DEIPR_RS05850
uniprot id: F0RNI0
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

693977:DEIPR RS01130
gene id: 693977:DEIPR_RS01130
uniprot id: F0RP66
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS08125
gene id: 693977:DEIPR_RS08125
uniprot id: F0RKF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

693977:DEIPR RS06055
gene id: 693977:DEIPR_RS06055
uniprot id: F0RNM1
names: Similarity
messages: Belongs to the PspA/IM30 family.

693977:DEIPR RS04965
gene id: 693977:DEIPR_RS04965
uniprot id: F0RMY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS03385
gene id: 693977:DEIPR_RS03385
uniprot id: F0RLC0
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS02105
gene id: 693977:DEIPR_RS02105
uniprot id: F0RJU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

693977:DEIPR RS05680
gene id: 693977:DEIPR_RS05680
uniprot id: F0RND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

693977:DEIPR RS12420
gene id: 693977:DEIPR_RS12420
uniprot id: F0RQL6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

693977:DEIPR RS04365
gene id: 693977:DEIPR_RS04365
uniprot id: F0RM89
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

693977:DEIPR RS10275
gene id: 693977:DEIPR_RS10275
uniprot id: F0RPV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

693977:DEIPR RS08070
gene id: 693977:DEIPR_RS08070
uniprot id: F0RKE8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

693977:DEIPR RS03480
gene id: 693977:DEIPR_RS03480
uniprot id: F0RLE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

693977:DEIPR RS00910
gene id: 693977:DEIPR_RS00910
uniprot id: F0RP22
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

693977:DEIPR RS05350
gene id: 693977:DEIPR_RS05350
uniprot id: F0RN66
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

693977:DEIPR RS01025
gene id: 693977:DEIPR_RS01025
uniprot id: F0RP43
names: Similarity
messages: Belongs to the DinB family.

693977:DEIPR RS13040
gene id: 693977:DEIPR_RS13040
uniprot id: F0RQY5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

693977:DEIPR RS07855
gene id: 693977:DEIPR_RS07855
uniprot id: F0RK40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

693977:DEIPR RS06840
gene id: 693977:DEIPR_RS06840
uniprot id: F0RJ65
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

693977:DEIPR RS12870
gene id: 693977:DEIPR_RS12870
uniprot id: F0RQV4
names: Similarity
messages: Belongs to the ParB family.

693977:DEIPR RS02060
gene id: 693977:DEIPR_RS02060
uniprot id: F0RJT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

693977:DEIPR RS10920
gene id: 693977:DEIPR_RS10920
uniprot id: F0RPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

693977:DEIPR RS03440
gene id: 693977:DEIPR_RS03440
uniprot id: F0RLD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

693977:DEIPR RS07760
gene id: 693977:DEIPR_RS07760
uniprot id: F0RK21
names: Cofactor
messages: Can also use Mn(2+) ion.

693977:DEIPR RS08965
gene id: 693977:DEIPR_RS08965
uniprot id: F0RLH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

693977:DEIPR RS13175
gene id: 693977:DEIPR_RS13175
uniprot id: F0RR13
names: Similarity
messages: Belongs to the peptidase S33 family.

693977:DEIPR RS09195
gene id: 693977:DEIPR_RS09195
uniprot id: F0RLM0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

693977:DEIPR RS06555
gene id: 693977:DEIPR_RS06555
uniprot id: F0RPA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

693977:DEIPR RS11325
gene id: 693977:DEIPR_RS11325
uniprot id: F0RPQ6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

693977:DEIPR RS10375
gene id: 693977:DEIPR_RS10375
uniprot id: F0RPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Membrane

693977:DEIPR RS00835
gene id: 693977:DEIPR_RS00835
uniprot id: F0RP13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

693977:DEIPR RS13130
gene id: 693977:DEIPR_RS13130
uniprot id: F0RR03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

693977:DEIPR RS07785
gene id: 693977:DEIPR_RS07785
uniprot id: F0RK26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS01630
gene id: 693977:DEIPR_RS01630
uniprot id: F0RJE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

693977:DEIPR RS05015
gene id: 693977:DEIPR_RS05015
uniprot id: F0RMZ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS02895
gene id: 693977:DEIPR_RS02895
uniprot id: F0RKN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

693977:DEIPR RS03320
gene id: 693977:DEIPR_RS03320
uniprot id: F0RLA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

693977:DEIPR RS03220
gene id: 693977:DEIPR_RS03220
uniprot id: F0RL18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

693977:DEIPR RS08900
gene id: 693977:DEIPR_RS08900
uniprot id: F0RL99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS06330
gene id: 693977:DEIPR_RS06330
uniprot id: F0RNZ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS08830
gene id: 693977:DEIPR_RS08830
uniprot id: F0RL85
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS04250
gene id: 693977:DEIPR_RS04250
uniprot id: F0RM66
names: Similarity
messages: Belongs to the disproportionating enzyme family.

693977:DEIPR RS00450
gene id: 693977:DEIPR_RS00450
uniprot id: F0RNF6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

693977:DEIPR RS06950
gene id: 693977:DEIPR_RS06950
uniprot id: F0RJ87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

693977:DEIPR RS11445
gene id: 693977:DEIPR_RS11445
uniprot id: F0RPT0
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS04565
gene id: 693977:DEIPR_RS04565
uniprot id: F0RMJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

693977:DEIPR RS09105
gene id: 693977:DEIPR_RS09105
uniprot id: F0RLK4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

693977:DEIPR RS06975
gene id: 693977:DEIPR_RS06975
uniprot id: F0RJ90
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

693977:DEIPR RS02085
gene id: 693977:DEIPR_RS02085
uniprot id: F0RJU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

693977:DEIPR RS08255
gene id: 693977:DEIPR_RS08255
uniprot id: F0RKQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

693977:DEIPR RS11105
gene id: 693977:DEIPR_RS11105
uniprot id: F0RPL5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

693977:DEIPR RS05390
gene id: 693977:DEIPR_RS05390
uniprot id: F0RN74
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

693977:DEIPR RS05945
gene id: 693977:DEIPR_RS05945
uniprot id: F0RNJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

693977:DEIPR RS09110
gene id: 693977:DEIPR_RS09110
uniprot id: F0RLK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

693977:DEIPR RS08935
gene id: 693977:DEIPR_RS08935
uniprot id: F0RLH3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

693977:DEIPR RS03975
gene id: 693977:DEIPR_RS03975
uniprot id: F0RLU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

693977:DEIPR RS02610
gene id: 693977:DEIPR_RS02610
uniprot id: F0RKI3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

693977:DEIPR RS02285
gene id: 693977:DEIPR_RS02285
uniprot id: F0RK51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS00745
gene id: 693977:DEIPR_RS00745
uniprot id: F0RNS8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS03455
gene id: 693977:DEIPR_RS03455
uniprot id: F0RLD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

693977:DEIPR RS10250
gene id: 693977:DEIPR_RS10250
uniprot id: F0RMT3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

693977:DEIPR RS03425
gene id: 693977:DEIPR_RS03425
uniprot id: F0RLC8
names: Similarity
messages: Belongs to the YciI family.

693977:DEIPR RS10730
gene id: 693977:DEIPR_RS10730
uniprot id: F0RQ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

693977:DEIPR RS04235
gene id: 693977:DEIPR_RS04235
uniprot id: F0RM63
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

693977:DEIPR RS08705
gene id: 693977:DEIPR_RS08705
uniprot id: F0RL59
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

693977:DEIPR RS12925
gene id: 693977:DEIPR_RS12925
uniprot id: F0RQW2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

693977:DEIPR RS08950
gene id: 693977:DEIPR_RS08950
uniprot id: F0RLH6
names: Similarity
messages: Belongs to the SCO1/2 family.

693977:DEIPR RS07290
gene id: 693977:DEIPR_RS07290
uniprot id: F0RJL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

693977:DEIPR RS07450
gene id: 693977:DEIPR_RS07450
uniprot id: F0RJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

693977:DEIPR RS11885
gene id: 693977:DEIPR_RS11885
uniprot id: F0RQB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

693977:DEIPR RS02325
gene id: 693977:DEIPR_RS02325
uniprot id: F0RK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS05450
gene id: 693977:DEIPR_RS05450
uniprot id: F0RN85
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS06265
gene id: 693977:DEIPR_RS06265
uniprot id: F0RNX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS09435
gene id: 693977:DEIPR_RS09435
uniprot id: F0RLY1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

693977:DEIPR RS00610
gene id: 693977:DEIPR_RS00610
uniprot id: F0RNQ3
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

693977:DEIPR RS01610
gene id: 693977:DEIPR_RS01610
uniprot id: F0RJD7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

693977:DEIPR RS09280
gene id: 693977:DEIPR_RS09280
uniprot id: F0RLV1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

693977:DEIPR RS02050
gene id: 693977:DEIPR_RS02050
uniprot id: F0RJT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

693977:DEIPR RS11020
gene id: 693977:DEIPR_RS11020
uniprot id: F0RPJ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

693977:DEIPR RS01250
gene id: 693977:DEIPR_RS01250
uniprot id: F0RIZ7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

693977:DEIPR RS06920
gene id: 693977:DEIPR_RS06920
uniprot id: F0RJ81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

693977:DEIPR RS06515
gene id: 693977:DEIPR_RS06515
uniprot id: F0RP95
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

693977:DEIPR RS00130
gene id: 693977:DEIPR_RS00130
uniprot id: F0RIU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

693977:DEIPR RS09415
gene id: 693977:DEIPR_RS09415
uniprot id: F0RLX8
names: Similarity
messages: Belongs to the UPF0102 family.

693977:DEIPR RS05595
gene id: 693977:DEIPR_RS05595
uniprot id: F0RNB3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

693977:DEIPR RS09250
gene id: 693977:DEIPR_RS09250
uniprot id: F0RLN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

693977:DEIPR RS04740
gene id: 693977:DEIPR_RS04740
uniprot id: F0RMU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS08440
gene id: 693977:DEIPR_RS08440
uniprot id: F0RKT6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

693977:DEIPR RS04015
gene id: 693977:DEIPR_RS04015
uniprot id: F0RM19
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

693977:DEIPR RS08115
gene id: 693977:DEIPR_RS08115
uniprot id: F0RKF7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

693977:DEIPR RS09610
gene id: 693977:DEIPR_RS09610
uniprot id: F0RM90
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

693977:DEIPR RS10680
gene id: 693977:DEIPR_RS10680
uniprot id: F0RQ35
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

693977:DEIPR RS03700
gene id: 693977:DEIPR_RS03700
uniprot id: F0RLP6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

693977:DEIPR RS01350
gene id: 693977:DEIPR_RS01350
uniprot id: F0RJ17
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

693977:DEIPR RS03530
gene id: 693977:DEIPR_RS03530
uniprot id: F0RLF0
names: Similarity
messages: Belongs to the asp23 family.

693977:DEIPR RS01770
gene id: 693977:DEIPR_RS01770
uniprot id: F0RJG4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

693977:DEIPR RS08265
gene id: 693977:DEIPR_RS08265
uniprot id: F0RKQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

693977:DEIPR RS01915
gene id: 693977:DEIPR_RS01915
uniprot id: F0RJR0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS11360
gene id: 693977:DEIPR_RS11360
uniprot id: F0RPR3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

693977:DEIPR RS07635
gene id: 693977:DEIPR_RS07635
uniprot id: F0RJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

693977:DEIPR RS02125
gene id: 693977:DEIPR_RS02125
uniprot id: F0RJV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

693977:DEIPR RS03450
gene id: 693977:DEIPR_RS03450
uniprot id: F0RLD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

693977:DEIPR RS05825
gene id: 693977:DEIPR_RS05825
uniprot id: F0RNH5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

693977:DEIPR RS10065
gene id: 693977:DEIPR_RS10065
uniprot id: F0RMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

693977:DEIPR RS00360
gene id: 693977:DEIPR_RS00360
uniprot id: F0RIY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

693977:DEIPR RS01065
gene id: 693977:DEIPR_RS01065
uniprot id: F0RP51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

693977:DEIPR RS03880
gene id: 693977:DEIPR_RS03880
uniprot id: F0RLS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS00640
gene id: 693977:DEIPR_RS00640
uniprot id: F0RNQ9
names: Similarity
messages: Belongs to the UPF0173 family.

693977:DEIPR RS10990
gene id: 693977:DEIPR_RS10990
uniprot id: F0RPJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS00325
gene id: 693977:DEIPR_RS00325
uniprot id: F0RIX4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

693977:DEIPR RS10035
gene id: 693977:DEIPR_RS10035
uniprot id: F0RMP0
names: Similarity
messages: Belongs to the universal stress protein A family.

693977:DEIPR RS01775
gene id: 693977:DEIPR_RS01775
uniprot id: F0RJG5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

693977:DEIPR RS07995
gene id: 693977:DEIPR_RS07995
uniprot id: F0RKD3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS10700
gene id: 693977:DEIPR_RS10700
uniprot id: F0RQ39
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

693977:DEIPR RS09400
gene id: 693977:DEIPR_RS09400
uniprot id: F0RLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS03340
gene id: 693977:DEIPR_RS03340
uniprot id: F0RLB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

693977:DEIPR RS07185
gene id: 693977:DEIPR_RS07185
uniprot id: F0RJJ5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

693977:DEIPR RS08715
gene id: 693977:DEIPR_RS08715
uniprot id: F0RL62
names: Similarity
messages: Belongs to the Nth/MutY family.

693977:DEIPR RS05190
gene id: 693977:DEIPR_RS05190
uniprot id: F0RN34
names: Similarity
messages: Belongs to the Nudix hydrolase family.

693977:DEIPR RS06290
gene id: 693977:DEIPR_RS06290
uniprot id: F0RNY4
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

693977:DEIPR RS06215
gene id: 693977:DEIPR_RS06215
uniprot id: F0RNW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

693977:DEIPR RS10825
gene id: 693977:DEIPR_RS10825
uniprot id: F0RPG0
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

693977:DEIPR RS07980
gene id: 693977:DEIPR_RS07980
uniprot id: F0RKD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

693977:DEIPR RS00020
gene id: 693977:DEIPR_RS00020
uniprot id: F0RIS3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

693977:DEIPR RS09935
gene id: 693977:DEIPR_RS09935
uniprot id: F0RMF1
names: Similarity
messages: Belongs to the peptidase C56 family.

693977:DEIPR RS10795
gene id: 693977:DEIPR_RS10795
uniprot id: F0RPF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

693977:DEIPR RS01135
gene id: 693977:DEIPR_RS01135
uniprot id: F0RP67
names: Similarity
messages: Belongs to the peptidase S1C family.

693977:DEIPR RS05765
gene id: 693977:DEIPR_RS05765
uniprot id: F0RNG3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

693977:DEIPR RS11335
gene id: 693977:DEIPR_RS11335
uniprot id: F0RPQ8
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS05985
gene id: 693977:DEIPR_RS05985
uniprot id: F0RNK8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

693977:DEIPR RS01255
gene id: 693977:DEIPR_RS01255
uniprot id: F0RIZ8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

693977:DEIPR RS13070
gene id: 693977:DEIPR_RS13070
uniprot id: F0RQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

693977:DEIPR RS00730
gene id: 693977:DEIPR_RS00730
uniprot id: F0RNS7
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

693977:DEIPR RS07915
gene id: 693977:DEIPR_RS07915
uniprot id: F0RKB7
names: Subcellular Location Annotation
messages: Secreted

693977:DEIPR RS08755
gene id: 693977:DEIPR_RS08755
uniprot id: F0RL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

693977:DEIPR RS10000
gene id: 693977:DEIPR_RS10000
uniprot id: F0RMN3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

693977:DEIPR RS02220
gene id: 693977:DEIPR_RS02220
uniprot id: F0RJX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS06640
gene id: 693977:DEIPR_RS06640
uniprot id: F0RPC0
names: Similarity
messages: Belongs to the GSP E family.

693977:DEIPR RS05535
gene id: 693977:DEIPR_RS05535
uniprot id: F0RNA1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

693977:DEIPR RS07055
gene id: 693977:DEIPR_RS07055
uniprot id: F0RJA5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

693977:DEIPR RS00060
gene id: 693977:DEIPR_RS00060
uniprot id: F0RIT1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

693977:DEIPR RS03950
gene id: 693977:DEIPR_RS03950
uniprot id: F0RLT7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS02035
gene id: 693977:DEIPR_RS02035
uniprot id: F0RJT4
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

693977:DEIPR RS01260
gene id: 693977:DEIPR_RS01260
uniprot id: F0RIZ9
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

693977:DEIPR RS03265
gene id: 693977:DEIPR_RS03265
uniprot id: F0RL27
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

693977:DEIPR RS05740
gene id: 693977:DEIPR_RS05740
uniprot id: F0RNF8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

693977:DEIPR RS05715
gene id: 693977:DEIPR_RS05715
uniprot id: F0RND7
names: Similarity
messages: Belongs to the peptidase S66 family.

693977:DEIPR RS06405
gene id: 693977:DEIPR_RS06405
uniprot id: F0RP05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

693977:DEIPR RS07365
gene id: 693977:DEIPR_RS07365
uniprot id: F0RJM8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

693977:DEIPR RS01085
gene id: 693977:DEIPR_RS01085
uniprot id: F0RP56
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

693977:DEIPR RS05845
gene id: 693977:DEIPR_RS05845
uniprot id: F0RNH9
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

693977:DEIPR RS10670
gene id: 693977:DEIPR_RS10670
uniprot id: F0RQ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

693977:DEIPR RS05065
gene id: 693977:DEIPR_RS05065
uniprot id: F0RN09
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

693977:DEIPR RS04635
gene id: 693977:DEIPR_RS04635
uniprot id: F0RML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

693977:DEIPR RS06655
gene id: 693977:DEIPR_RS06655
uniprot id: F0RPC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

693977:DEIPR RS08955
gene id: 693977:DEIPR_RS08955
uniprot id: F0RLH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

693977:DEIPR RS05405
gene id: 693977:DEIPR_RS05405
uniprot id: F0RN76
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

693977:DEIPR RS08285
gene id: 693977:DEIPR_RS08285
uniprot id: F0RKQ9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

693977:DEIPR RS00945
gene id: 693977:DEIPR_RS00945
uniprot id: F0RP27
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

693977:DEIPR RS05240
gene id: 693977:DEIPR_RS05240
uniprot id: F0RN44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

693977:DEIPR RS04515
gene id: 693977:DEIPR_RS04515
uniprot id: F0RMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

693977:DEIPR RS12415
gene id: 693977:DEIPR_RS12415
uniprot id: F0RQL5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

693977:DEIPR RS08555
gene id: 693977:DEIPR_RS08555
uniprot id: F0RKV9
names: Similarity
messages: Belongs to the PstS family.

693977:DEIPR RS02530
gene id: 693977:DEIPR_RS02530
uniprot id: F0RK99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

693977:DEIPR RS10185
gene id: 693977:DEIPR_RS10185
uniprot id: F0RMS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

693977:DEIPR RS11525
gene id: 693977:DEIPR_RS11525
uniprot id: F0RPU6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

693977:DEIPR RS08245
gene id: 693977:DEIPR_RS08245
uniprot id: F0RKQ1
names: Similarity
messages: Belongs to the peptidase S33 family.

693977:DEIPR RS11875
gene id: 693977:DEIPR_RS11875
uniprot id: F0RQB6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

693977:DEIPR RS08275
gene id: 693977:DEIPR_RS08275
uniprot id: F0RKQ7
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

693977:DEIPR RS09685
gene id: 693977:DEIPR_RS09685
uniprot id: O34136
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity).
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity (By similarity).

693977:DEIPR RS06155
gene id: 693977:DEIPR_RS06155
uniprot id: F0RNV7
names: Similarity
messages: Belongs to the peptidase S51 family.

693977:DEIPR RS06380
gene id: 693977:DEIPR_RS06380
uniprot id: F0RP00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

693977:DEIPR RS08170
gene id: 693977:DEIPR_RS08170
uniprot id: F0RKG9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

693977:DEIPR RS01310
gene id: 693977:DEIPR_RS01310
uniprot id: F0RJ09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

693977:DEIPR RS10540
gene id: 693977:DEIPR_RS10540
uniprot id: F0RQ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

693977:DEIPR RS03985
gene id: 693977:DEIPR_RS03985
uniprot id: F0RLU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

693977:DEIPR RS02655
gene id: 693977:DEIPR_RS02655
uniprot id: F0RKJ2
names: Similarity
messages: Belongs to the hemerythrin family.

693977:DEIPR RS07940
gene id: 693977:DEIPR_RS07940
uniprot id: F0RKC2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

693977:DEIPR RS07410
gene id: 693977:DEIPR_RS07410
uniprot id: F0RJN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

693977:DEIPR RS03675
gene id: 693977:DEIPR_RS03675
uniprot id: F0RLP1
names: Similarity
messages: Belongs to the histone deacetylase family.

693977:DEIPR RS11955
gene id: 693977:DEIPR_RS11955
uniprot id: F0RQD2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

693977:DEIPR RS01605
gene id: 693977:DEIPR_RS01605
uniprot id: F0RJD6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

693977:DEIPR RS01835
gene id: 693977:DEIPR_RS01835
uniprot id: F0RJH9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

693977:DEIPR RS10640
gene id: 693977:DEIPR_RS10640
uniprot id: F0RQ27
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

693977:DEIPR RS07190
gene id: 693977:DEIPR_RS07190
uniprot id: F0RJJ6
names: Similarity
messages: Belongs to the asp23 family.

693977:DEIPR RS09185
gene id: 693977:DEIPR_RS09185
uniprot id: F0RLL8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

693977:DEIPR RS05930
gene id: 693977:DEIPR_RS05930
uniprot id: F0RNJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

693977:DEIPR RS01030
gene id: 693977:DEIPR_RS01030
uniprot id: F0RP44
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

693977:DEIPR RS01230
gene id: 693977:DEIPR_RS01230
uniprot id: F0RIZ3
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS13440
gene id: 693977:DEIPR_RS13440
uniprot id: F0RR63
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

693977:DEIPR RS04620
gene id: 693977:DEIPR_RS04620
uniprot id: F0RML1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

693977:DEIPR RS01505
gene id: 693977:DEIPR_RS01505
uniprot id: F0RJ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS01600
gene id: 693977:DEIPR_RS01600
uniprot id: F0RJD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS06580
gene id: 693977:DEIPR_RS06580
uniprot id: F0RPA8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

693977:DEIPR RS00295
gene id: 693977:DEIPR_RS00295
uniprot id: F0RIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS02700
gene id: 693977:DEIPR_RS02700
uniprot id: F0RKJ7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS11375
gene id: 693977:DEIPR_RS11375
uniprot id: F0RPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

693977:DEIPR RS10265
gene id: 693977:DEIPR_RS10265
uniprot id: F0RMT6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

693977:DEIPR RS09120
gene id: 693977:DEIPR_RS09120
uniprot id: F0RLK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

693977:DEIPR RS00300
gene id: 693977:DEIPR_RS00300
uniprot id: F0RIW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS02535
gene id: 693977:DEIPR_RS02535
uniprot id: F0RKA0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

693977:DEIPR RS05800
gene id: 693977:DEIPR_RS05800
uniprot id: F0RNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

693977:DEIPR RS05255
gene id: 693977:DEIPR_RS05255
uniprot id: F0RN47
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS06960
gene id: 693977:DEIPR_RS06960
uniprot id: F0RJ89
names: Similarity
messages: Belongs to the threonine synthase family.

693977:DEIPR RS02795
gene id: 693977:DEIPR_RS02795
uniprot id: F0RKL6
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS11500
gene id: 693977:DEIPR_RS11500
uniprot id: F0RPU1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

693977:DEIPR RS01070
gene id: 693977:DEIPR_RS01070
uniprot id: F0RP52
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

693977:DEIPR RS08560
gene id: 693977:DEIPR_RS08560
uniprot id: F0RKW0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

693977:DEIPR RS03310
gene id: 693977:DEIPR_RS03310
uniprot id: F0RLA6
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS09445
gene id: 693977:DEIPR_RS09445
uniprot id: F0RLY3
names: Similarity
messages: Belongs to the FBPase class 2 family.

693977:DEIPR RS02470
gene id: 693977:DEIPR_RS02470
uniprot id: F0RK87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

693977:DEIPR RS07250
gene id: 693977:DEIPR_RS07250
uniprot id: F0RJK8
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS10460
gene id: 693977:DEIPR_RS10460
uniprot id: F0RPZ2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

693977:DEIPR RS05125
gene id: 693977:DEIPR_RS05125
uniprot id: F0RN21
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS13710
gene id: 693977:DEIPR_RS13710
uniprot id: F0RRA6
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

693977:DEIPR RS00920
gene id: 693977:DEIPR_RS00920
uniprot id: F0RP24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

693977:DEIPR RS04590
gene id: 693977:DEIPR_RS04590
uniprot id: F0RMK5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

693977:DEIPR RS04260
gene id: 693977:DEIPR_RS04260
uniprot id: F0RM68
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS05980
gene id: 693977:DEIPR_RS05980
uniprot id: F0RNK7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

693977:DEIPR RS04915
gene id: 693977:DEIPR_RS04915
uniprot id: F0RMX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

693977:DEIPR RS10545
gene id: 693977:DEIPR_RS10545
uniprot id: F0RQ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

693977:DEIPR RS09695
gene id: 693977:DEIPR_RS09695
uniprot id: F0RMA6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

693977:DEIPR RS09205
gene id: 693977:DEIPR_RS09205
uniprot id: F0RLM2
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS01990
gene id: 693977:DEIPR_RS01990
uniprot id: F0RJS5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS14215
gene id: 693977:DEIPR_RS14215
uniprot id: F0RPT5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

693977:DEIPR RS05100
gene id: 693977:DEIPR_RS05100
uniprot id: F0RN16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

693977:DEIPR RS02145
gene id: 693977:DEIPR_RS02145
uniprot id: F0RJV6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

693977:DEIPR RS06195
gene id: 693977:DEIPR_RS06195
uniprot id: F0RNW5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

693977:DEIPR RS00160
gene id: 693977:DEIPR_RS00160
uniprot id: F0RIV0
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS03830
gene id: 693977:DEIPR_RS03830
uniprot id: F0RLR6
names: Similarity
messages: Belongs to the Dps family.

693977:DEIPR RS05260
gene id: 693977:DEIPR_RS05260
uniprot id: F0RN48
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS04375
gene id: 693977:DEIPR_RS04375
uniprot id: F0RMG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

693977:DEIPR RS01210
gene id: 693977:DEIPR_RS01210
uniprot id: F0RIY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

693977:DEIPR RS02215
gene id: 693977:DEIPR_RS02215
uniprot id: F0RJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

693977:DEIPR RS03785
gene id: 693977:DEIPR_RS03785
uniprot id: F0RLR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

693977:DEIPR RS03325
gene id: 693977:DEIPR_RS03325
uniprot id: F0RLA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

693977:DEIPR RS02715
gene id: 693977:DEIPR_RS02715
uniprot id: F0RKK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

693977:DEIPR RS06300
gene id: 693977:DEIPR_RS06300
uniprot id: F0RNY6
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS11520
gene id: 693977:DEIPR_RS11520
uniprot id: F0RPU5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

693977:DEIPR RS04685
gene id: 693977:DEIPR_RS04685
uniprot id: F0RMM4
names: Similarity
messages: Belongs to the peptidase S8 family.

693977:DEIPR RS01060
gene id: 693977:DEIPR_RS01060
uniprot id: F0RP50
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

693977:DEIPR RS06165
gene id: 693977:DEIPR_RS06165
uniprot id: F0RNV9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

693977:DEIPR RS01050
gene id: 693977:DEIPR_RS01050
uniprot id: F0RP48
names: Similarity
messages: Belongs to the SAICAR synthetase family.

693977:DEIPR RS02990
gene id: 693977:DEIPR_RS02990
uniprot id: F0RKX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

693977:DEIPR RS01515
gene id: 693977:DEIPR_RS01515
uniprot id: F0RJ51
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS02380
gene id: 693977:DEIPR_RS02380
uniprot id: F0RK70
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

693977:DEIPR RS09030
gene id: 693977:DEIPR_RS09030
uniprot id: F0RLI9
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

693977:DEIPR RS05725
gene id: 693977:DEIPR_RS05725
uniprot id: F0RND9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Cell envelope
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

693977:DEIPR RS02925
gene id: 693977:DEIPR_RS02925
uniprot id: F0RKP2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

693977:DEIPR RS03420
gene id: 693977:DEIPR_RS03420
uniprot id: F0RLC7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

693977:DEIPR RS10305
gene id: 693977:DEIPR_RS10305
uniprot id: F0RPW0
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS00025
gene id: 693977:DEIPR_RS00025
uniprot id: F0RIS4
names: Similarity
messages: Belongs to the pyruvate kinase family.

693977:DEIPR RS08165
gene id: 693977:DEIPR_RS08165
uniprot id: F0RKG8
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS02095
gene id: 693977:DEIPR_RS02095
uniprot id: F0RJU6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

693977:DEIPR RS09125
gene id: 693977:DEIPR_RS09125
uniprot id: F0RLK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

693977:DEIPR RS04155
gene id: 693977:DEIPR_RS04155
uniprot id: F0RM47
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

693977:DEIPR RS05605
gene id: 693977:DEIPR_RS05605
uniprot id: F0RNB5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS02500
gene id: 693977:DEIPR_RS02500
uniprot id: F0RK93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

693977:DEIPR RS08250
gene id: 693977:DEIPR_RS08250
uniprot id: F0RKQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS12750
gene id: 693977:DEIPR_RS12750
uniprot id: F0RQT0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

693977:DEIPR RS00490
gene id: 693977:DEIPR_RS00490
uniprot id: F0RNN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

693977:DEIPR RS10570
gene id: 693977:DEIPR_RS10570
uniprot id: F0RQ14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS14370
gene id: 693977:DEIPR_RS14370
uniprot id: F0RLL9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

693977:DEIPR RS04570
gene id: 693977:DEIPR_RS04570
uniprot id: F0RMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

693977:DEIPR RS07240
gene id: 693977:DEIPR_RS07240
uniprot id: F0RJK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

693977:DEIPR RS08300
gene id: 693977:DEIPR_RS08300
uniprot id: F0RKR2
names: Similarity
messages: Belongs to the peptidase M29 family.

693977:DEIPR RS05600
gene id: 693977:DEIPR_RS05600
uniprot id: F0RNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

693977:DEIPR RS00390
gene id: 693977:DEIPR_RS00390
uniprot id: F0RNE4
names: Similarity
messages: Belongs to the PstS family.

693977:DEIPR RS01240
gene id: 693977:DEIPR_RS01240
uniprot id: F0RIZ5
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

693977:DEIPR RS10125
gene id: 693977:DEIPR_RS10125
uniprot id: F0RMQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

693977:DEIPR RS02495
gene id: 693977:DEIPR_RS02495
uniprot id: F0RK92
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

693977:DEIPR RS09870
gene id: 693977:DEIPR_RS09870
uniprot id: F0RMD7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

693977:DEIPR RS03845
gene id: 693977:DEIPR_RS03845
uniprot id: F0RLR9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

693977:DEIPR RS11740
gene id: 693977:DEIPR_RS11740
uniprot id: F0RQ90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS07225
gene id: 693977:DEIPR_RS07225
uniprot id: F0RJK3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

693977:DEIPR RS02045
gene id: 693977:DEIPR_RS02045
uniprot id: F0RJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

693977:DEIPR RS12900
gene id: 693977:DEIPR_RS12900
uniprot id: F0RQV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

693977:DEIPR RS10800
gene id: 693977:DEIPR_RS10800
uniprot id: F0RPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

693977:DEIPR RS02180
gene id: 693977:DEIPR_RS02180
uniprot id: F0RJW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

693977:DEIPR RS02175
gene id: 693977:DEIPR_RS02175
uniprot id: F0RJW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

693977:DEIPR RS10750
gene id: 693977:DEIPR_RS10750
uniprot id: F0RQ49
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

693977:DEIPR RS01885
gene id: 693977:DEIPR_RS01885
uniprot id: F0RJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

693977:DEIPR RS09960
gene id: 693977:DEIPR_RS09960
uniprot id: F0RMF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS10100
gene id: 693977:DEIPR_RS10100
uniprot id: F0RMQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

693977:DEIPR RS11475
gene id: 693977:DEIPR_RS11475
uniprot id: F0RPT6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

693977:DEIPR RS03725
gene id: 693977:DEIPR_RS03725
uniprot id: F0RLQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

693977:DEIPR RS07830
gene id: 693977:DEIPR_RS07830
uniprot id: F0RK35
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS03890
gene id: 693977:DEIPR_RS03890
uniprot id: F0RLS9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

693977:DEIPR RS04480
gene id: 693977:DEIPR_RS04480
uniprot id: F0RMI2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

693977:DEIPR RS02270
gene id: 693977:DEIPR_RS02270
uniprot id: F0RK48
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS06850
gene id: 693977:DEIPR_RS06850
uniprot id: F0RJ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

693977:DEIPR RS02185
gene id: 693977:DEIPR_RS02185
uniprot id: F0RJW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

693977:DEIPR RS04505
gene id: 693977:DEIPR_RS04505
uniprot id: F0RMI7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

693977:DEIPR RS04655
gene id: 693977:DEIPR_RS04655
uniprot id: F0RML8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

693977:DEIPR RS03995
gene id: 693977:DEIPR_RS03995
uniprot id: F0RLU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

693977:DEIPR RS07215
gene id: 693977:DEIPR_RS07215
uniprot id: F0RJK1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

693977:DEIPR RS13125
gene id: 693977:DEIPR_RS13125
uniprot id: F0RR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS07180
gene id: 693977:DEIPR_RS07180
uniprot id: F0RJJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

693977:DEIPR RS02345
gene id: 693977:DEIPR_RS02345
uniprot id: F0RK63
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

693977:DEIPR RS08565
gene id: 693977:DEIPR_RS08565
uniprot id: F0RKW1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

693977:DEIPR RS02280
gene id: 693977:DEIPR_RS02280
uniprot id: F0RK50
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

693977:DEIPR RS00505
gene id: 693977:DEIPR_RS00505
uniprot id: F0RNN3
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

693977:DEIPR RS04510
gene id: 693977:DEIPR_RS04510
uniprot id: F0RMI8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

693977:DEIPR RS02290
gene id: 693977:DEIPR_RS02290
uniprot id: F0RK52
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

693977:DEIPR RS07140
gene id: 693977:DEIPR_RS07140
uniprot id: F0RJI6
names: Similarity
messages: Belongs to the acetokinase family.

693977:DEIPR RS13145
gene id: 693977:DEIPR_RS13145
uniprot id: F0RR06
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

693977:DEIPR RS08975
gene id: 693977:DEIPR_RS08975
uniprot id: F0RLI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

693977:DEIPR RS03025
gene id: 693977:DEIPR_RS03025
uniprot id: F0RKY0
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

693977:DEIPR RS06685
gene id: 693977:DEIPR_RS06685
uniprot id: F0RPC9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

693977:DEIPR RS08880
gene id: 693977:DEIPR_RS08880
uniprot id: F0RL95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

693977:DEIPR RS06045
gene id: 693977:DEIPR_RS06045
uniprot id: F0RNL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS00775
gene id: 693977:DEIPR_RS00775
uniprot id: F0RNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

693977:DEIPR RS01035
gene id: 693977:DEIPR_RS01035
uniprot id: F0RP45
names: Similarity
messages: Belongs to the asparaginase 1 family.

693977:DEIPR RS05575
gene id: 693977:DEIPR_RS05575
uniprot id: F0RNA9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

693977:DEIPR RS13195
gene id: 693977:DEIPR_RS13195
uniprot id: F0RR17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

693977:DEIPR RS09100
gene id: 693977:DEIPR_RS09100
uniprot id: F0RLK3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

693977:DEIPR RS04180
gene id: 693977:DEIPR_RS04180
uniprot id: F0RM52
names: Similarity
messages: Belongs to the OsmC/Ohr family.

693977:DEIPR RS05195
gene id: 693977:DEIPR_RS05195
uniprot id: F0RN35
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

693977:DEIPR RS10620
gene id: 693977:DEIPR_RS10620
uniprot id: F0RQ23
names: Subcellular Location Annotation
messages: Cytoplasm

693977:DEIPR RS04720
gene id: 693977:DEIPR_RS04720
uniprot id: F0RMU0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

693977:DEIPR RS04245
gene id: 693977:DEIPR_RS04245
uniprot id: F0RM65
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

693977:DEIPR RS03905
gene id: 693977:DEIPR_RS03905
uniprot id: F0RLT2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

693977:DEIPR RS02900
gene id: 693977:DEIPR_RS02900
uniprot id: F0RKN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

693977:DEIPR RS09745
gene id: 693977:DEIPR_RS09745
uniprot id: F0RMB3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

693977:DEIPR RS12945
gene id: 693977:DEIPR_RS12945
uniprot id: F0RQW7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

693977:DEIPR RS02155
gene id: 693977:DEIPR_RS02155
uniprot id: F0RJV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

693977:DEIPR RS11395
gene id: 693977:DEIPR_RS11395
uniprot id: F0RPS0
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS00635
gene id: 693977:DEIPR_RS00635
uniprot id: F0RNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS05070
gene id: 693977:DEIPR_RS05070
uniprot id: F0RN10
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

693977:DEIPR RS11440
gene id: 693977:DEIPR_RS11440
uniprot id: F0RPS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS01940
gene id: 693977:DEIPR_RS01940
uniprot id: F0RJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

693977:DEIPR RS06990
gene id: 693977:DEIPR_RS06990
uniprot id: F0RJ93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

693977:DEIPR RS05465
gene id: 693977:DEIPR_RS05465
uniprot id: F0RN87
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS06755
gene id: 693977:DEIPR_RS06755
uniprot id: F0RPE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

693977:DEIPR RS01320
gene id: 693977:DEIPR_RS01320
uniprot id: F0RJ11
names: Similarity
messages: Belongs to the UPF0047 family.

693977:DEIPR RS09335
gene id: 693977:DEIPR_RS09335
uniprot id: F0RLW2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

693977:DEIPR RS02450
gene id: 693977:DEIPR_RS02450
uniprot id: F0RK83
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

693977:DEIPR RS02875
gene id: 693977:DEIPR_RS02875
uniprot id: F0RKN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

693977:DEIPR RS05920
gene id: 693977:DEIPR_RS05920
uniprot id: F0RNJ4
names: Similarity
messages: Belongs to the Skp family.

693977:DEIPR RS08535
gene id: 693977:DEIPR_RS08535
uniprot id: F0RKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS01845
gene id: 693977:DEIPR_RS01845
uniprot id: F0RJI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

693977:DEIPR RS02720
gene id: 693977:DEIPR_RS02720
uniprot id: F0RKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

693977:DEIPR RS00620
gene id: 693977:DEIPR_RS00620
uniprot id: F0RNQ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

693977:DEIPR RS05610
gene id: 693977:DEIPR_RS05610
uniprot id: F0RNB6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

693977:DEIPR RS04270
gene id: 693977:DEIPR_RS04270
uniprot id: F0RM70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

693977:DEIPR RS09750
gene id: 693977:DEIPR_RS09750
uniprot id: F0RMB4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

693977:DEIPR RS08630
gene id: 693977:DEIPR_RS08630
uniprot id: F0RL44
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

693977:DEIPR RS04055
gene id: 693977:DEIPR_RS04055
uniprot id: F0RM27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

693977:DEIPR RS11690
gene id: 693977:DEIPR_RS11690
uniprot id: F0RQ78
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS07400
gene id: 693977:DEIPR_RS07400
uniprot id: F0RJN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

693977:DEIPR RS11215
gene id: 693977:DEIPR_RS11215
uniprot id: F0RPN5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

693977:DEIPR RS13235
gene id: 693977:DEIPR_RS13235
uniprot id: F0RR25
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

693977:DEIPR RS06420
gene id: 693977:DEIPR_RS06420
uniprot id: F0RP08
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

693977:DEIPR RS00950
gene id: 693977:DEIPR_RS00950
uniprot id: F0RP28
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

693977:DEIPR RS10550
gene id: 693977:DEIPR_RS10550
uniprot id: F0RQ10
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

693977:DEIPR RS05130
gene id: 693977:DEIPR_RS05130
uniprot id: F0RN22
names: Similarity
messages: Belongs to the UPF0225 family.

693977:DEIPR RS08910
gene id: 693977:DEIPR_RS08910
uniprot id: F0RLG9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

693977:DEIPR RS13140
gene id: 693977:DEIPR_RS13140
uniprot id: F0RR05
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

693977:DEIPR RS06170
gene id: 693977:DEIPR_RS06170
uniprot id: F0RNW0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

693977:DEIPR RS08680
gene id: 693977:DEIPR_RS08680
uniprot id: F0RL54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

693977:DEIPR RS10285
gene id: 693977:DEIPR_RS10285
uniprot id: F0RPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

693977:DEIPR RS02090
gene id: 693977:DEIPR_RS02090
uniprot id: F0RJU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

693977:DEIPR RS02560
gene id: 693977:DEIPR_RS02560
uniprot id: F0RKA5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

693977:DEIPR RS01735
gene id: 693977:DEIPR_RS01735
uniprot id: F0RJG0
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

693977:DEIPR RS10745
gene id: 693977:DEIPR_RS10745
uniprot id: F0RQ48
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS09310
gene id: 693977:DEIPR_RS09310
uniprot id: F0RLV7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

693977:DEIPR RS00800
gene id: 693977:DEIPR_RS00800
uniprot id: F0RNT9
names: Similarity
messages: Belongs to the peptidase S58 family.

693977:DEIPR RS00710
gene id: 693977:DEIPR_RS00710
uniprot id: F0RNS3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

693977:DEIPR RS07235
gene id: 693977:DEIPR_RS07235
uniprot id: F0RJK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

693977:DEIPR RS13010
gene id: 693977:DEIPR_RS13010
uniprot id: F0RQX9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

693977:DEIPR RS02070
gene id: 693977:DEIPR_RS02070
uniprot id: F0RJU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

693977:DEIPR RS04110
gene id: 693977:DEIPR_RS04110
uniprot id: F0RM38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

693977:DEIPR RS07125
gene id: 693977:DEIPR_RS07125
uniprot id: F0RJB7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

693977:DEIPR RS10300
gene id: 693977:DEIPR_RS10300
uniprot id: F0RPV9
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS05755
gene id: 693977:DEIPR_RS05755
uniprot id: F0RNG1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

693977:DEIPR RS06460
gene id: 693977:DEIPR_RS06460
uniprot id: F0RP84
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

693977:DEIPR RS03775
gene id: 693977:DEIPR_RS03775
uniprot id: F0RLR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

693977:DEIPR RS09480
gene id: 693977:DEIPR_RS09480
uniprot id: F0RLZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

693977:DEIPR RS03485
gene id: 693977:DEIPR_RS03485
uniprot id: F0RLE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

693977:DEIPR RS04575
gene id: 693977:DEIPR_RS04575
uniprot id: F0RMK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

693977:DEIPR RS05420
gene id: 693977:DEIPR_RS05420
uniprot id: F0RN79
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

693977:DEIPR RS09755
gene id: 693977:DEIPR_RS09755
uniprot id: F0RMB5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

693977:DEIPR RS03430
gene id: 693977:DEIPR_RS03430
uniprot id: F0RLC9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

693977:DEIPR RS03375
gene id: 693977:DEIPR_RS03375
uniprot id: F0RLB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

693977:DEIPR RS10760
gene id: 693977:DEIPR_RS10760
uniprot id: F0RPE7
names: Similarity
messages: Belongs to the arginase family.

693977:DEIPR RS02120
gene id: 693977:DEIPR_RS02120
uniprot id: F0RJV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

693977:DEIPR RS05160
gene id: 693977:DEIPR_RS05160
uniprot id: F0RN28
names: Similarity
messages: Belongs to the peptidase S41A family.

693977:DEIPR RS06455
gene id: 693977:DEIPR_RS06455
uniprot id: F0RP83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

693977:DEIPR RS03395
gene id: 693977:DEIPR_RS03395
uniprot id: F0RLC2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

693977:DEIPR RS04070
gene id: 693977:DEIPR_RS04070
uniprot id: F0RM30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS07370
gene id: 693977:DEIPR_RS07370
uniprot id: F0RJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

693977:DEIPR RS07035
gene id: 693977:DEIPR_RS07035
uniprot id: F0RJA1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS08145
gene id: 693977:DEIPR_RS08145
uniprot id: F0RKG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

693977:DEIPR RS12920
gene id: 693977:DEIPR_RS12920
uniprot id: F0RQW1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

693977:DEIPR RS07935
gene id: 693977:DEIPR_RS07935
uniprot id: F0RKC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

693977:DEIPR RS05075
gene id: 693977:DEIPR_RS05075
uniprot id: F0RN11
names: Cofactor
names: Similarity
messages: Belongs to the cytochrome b560 family.
messages: The heme is bound between the two transmembrane subunits.

693977:DEIPR RS01975
gene id: 693977:DEIPR_RS01975
uniprot id: F0RJS2
names: Similarity
messages: Belongs to the UbiD family.

693977:DEIPR RS07100
gene id: 693977:DEIPR_RS07100
uniprot id: F0RJB2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS12770
gene id: 693977:DEIPR_RS12770
uniprot id: F0RQT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

693977:DEIPR RS07255
gene id: 693977:DEIPR_RS07255
uniprot id: F0RJK9
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS02130
gene id: 693977:DEIPR_RS02130
uniprot id: F0RJV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

693977:DEIPR RS10420
gene id: 693977:DEIPR_RS10420
uniprot id: F0RPY4
names: Subcellular Location Annotation
messages: Membrane

693977:DEIPR RS00105
gene id: 693977:DEIPR_RS00105
uniprot id: F0RIU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

693977:DEIPR RS04885
gene id: 693977:DEIPR_RS04885
uniprot id: F0RMX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS10235
gene id: 693977:DEIPR_RS10235
uniprot id: F0RMT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS01020
gene id: 693977:DEIPR_RS01020
uniprot id: F0RP42
names: Similarity
messages: Belongs to the DinB family.

693977:DEIPR RS06335
gene id: 693977:DEIPR_RS06335
uniprot id: F0RNZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

693977:DEIPR RS08155
gene id: 693977:DEIPR_RS08155
uniprot id: F0RKG6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

693977:DEIPR RS04920
gene id: 693977:DEIPR_RS04920
uniprot id: F0RMY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

693977:DEIPR RS12930
gene id: 693977:DEIPR_RS12930
uniprot id: F0RQW3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

693977:DEIPR RS06505
gene id: 693977:DEIPR_RS06505
uniprot id: F0RP93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

693977:DEIPR RS07960
gene id: 693977:DEIPR_RS07960
uniprot id: F0RKC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

693977:DEIPR RS10155
gene id: 693977:DEIPR_RS10155
uniprot id: F0RMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

693977:DEIPR RS07950
gene id: 693977:DEIPR_RS07950
uniprot id: F0RKC4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

693977:DEIPR RS05490
gene id: 693977:DEIPR_RS05490
uniprot id: F0RN92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).