688269:THETH RS08970
gene id: 688269:THETH_RS08970
uniprot id: F7YVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

688269:THETH RS06175
gene id: 688269:THETH_RS06175
uniprot id: F7YTR2
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS00685
gene id: 688269:THETH_RS00685
uniprot id: F7YUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS03095
gene id: 688269:THETH_RS03095
uniprot id: F7YXQ7
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS01805
gene id: 688269:THETH_RS01805
uniprot id: F7YVF3
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: In the C-terminal section; belongs to the NAD synthetase family.

688269:THETH RS08465
gene id: 688269:THETH_RS08465
uniprot id: F7YXE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS08340
gene id: 688269:THETH_RS08340
uniprot id: F7YVP1
names: Similarity
messages: Belongs to the peptidase S1C family.

688269:THETH RS05340
gene id: 688269:THETH_RS05340
uniprot id: F7YYU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS04200
gene id: 688269:THETH_RS04200
uniprot id: F7YY92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

688269:THETH RS05905
gene id: 688269:THETH_RS05905
uniprot id: F7YTL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

688269:THETH RS07655
gene id: 688269:THETH_RS07655
uniprot id: F7YTY5
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

688269:THETH RS06165
gene id: 688269:THETH_RS06165
uniprot id: F7YTR0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

688269:THETH RS09440
gene id: 688269:THETH_RS09440
uniprot id: F7YWD6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

688269:THETH RS03775
gene id: 688269:THETH_RS03775
uniprot id: F7YY23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

688269:THETH RS03610
gene id: 688269:THETH_RS03610
uniprot id: F7YXZ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS02785
gene id: 688269:THETH_RS02785
uniprot id: F7YXK1
names: Similarity
messages: Belongs to the YggT family.

688269:THETH RS01600
gene id: 688269:THETH_RS01600
uniprot id: F7YVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

688269:THETH RS09670
gene id: 688269:THETH_RS09670
uniprot id: F7YWH6
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS01670
gene id: 688269:THETH_RS01670
uniprot id: F7YVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

688269:THETH RS10185
gene id: 688269:THETH_RS10185
uniprot id: F7YWR0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

688269:THETH RS05505
gene id: 688269:THETH_RS05505
uniprot id: F7YYX1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

688269:THETH RS08960
gene id: 688269:THETH_RS08960
uniprot id: F7YXF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

688269:THETH RS02520
gene id: 688269:THETH_RS02520
uniprot id: F7YWZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

688269:THETH RS06305
gene id: 688269:THETH_RS06305
uniprot id: F7YUB9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

688269:THETH RS06540
gene id: 688269:THETH_RS06540
uniprot id: F7YUF7
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02525
gene id: 688269:THETH_RS02525
uniprot id: F7YWZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

688269:THETH RS04525
gene id: 688269:THETH_RS04525
uniprot id: F7YYF1
names: Similarity
messages: Belongs to the peptidase S41A family.

688269:THETH RS03735
gene id: 688269:THETH_RS03735
uniprot id: F7YY15
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

688269:THETH RS03930
gene id: 688269:THETH_RS03930
uniprot id: F7YX48
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

688269:THETH RS03100
gene id: 688269:THETH_RS03100
uniprot id: F7YXQ8
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02790
gene id: 688269:THETH_RS02790
uniprot id: F7YXK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS03615
gene id: 688269:THETH_RS03615
uniprot id: F7YX37
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

688269:THETH RS04235
gene id: 688269:THETH_RS04235
uniprot id: F7YY99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS03475
gene id: 688269:THETH_RS03475
uniprot id: F7YXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

688269:THETH RS04170
gene id: 688269:THETH_RS04170
uniprot id: F7YY86
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

688269:THETH RS06250
gene id: 688269:THETH_RS06250
uniprot id: F7YUA7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

688269:THETH RS01495
gene id: 688269:THETH_RS01495
uniprot id: F7YWU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

688269:THETH RS09795
gene id: 688269:THETH_RS09795
uniprot id: F7YWJ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

688269:THETH RS10190
gene id: 688269:THETH_RS10190
uniprot id: F7YWR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

688269:THETH RS05170
gene id: 688269:THETH_RS05170
uniprot id: F7YYR4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

688269:THETH RS08880
gene id: 688269:THETH_RS08880
uniprot id: F7YVY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS09295
gene id: 688269:THETH_RS09295
uniprot id: F7YWB5
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

688269:THETH RS00885
gene id: 688269:THETH_RS00885
uniprot id: F7YUZ5
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS01565
gene id: 688269:THETH_RS01565
uniprot id: F7YVA8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

688269:THETH RS04270
gene id: 688269:THETH_RS04270
uniprot id: F7YYA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

688269:THETH RS03670
gene id: 688269:THETH_RS03670
uniprot id: F7YY06
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

688269:THETH RS00875
gene id: 688269:THETH_RS00875
uniprot id: F7YUZ3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

688269:THETH RS01555
gene id: 688269:THETH_RS01555
uniprot id: F7YVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS06665
gene id: 688269:THETH_RS06665
uniprot id: F7YTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS02595
gene id: 688269:THETH_RS02595
uniprot id: F7YX09
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

688269:THETH RS08985
gene id: 688269:THETH_RS08985
uniprot id: F7YW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS06875
gene id: 688269:THETH_RS06875
uniprot id: F7YTW7
names: Cofactor
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

688269:THETH RS07125
gene id: 688269:THETH_RS07125
uniprot id: F7YUJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

688269:THETH RS07950
gene id: 688269:THETH_RS07950
uniprot id: F7YU38
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

688269:THETH RS05115
gene id: 688269:THETH_RS05115
uniprot id: F7YYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

688269:THETH RS00040
gene id: 688269:THETH_RS00040
uniprot id: F7YTD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

688269:THETH RS05575
gene id: 688269:THETH_RS05575
uniprot id: F7YTG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS07160
gene id: 688269:THETH_RS07160
uniprot id: F7YUJ9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

688269:THETH RS00575
gene id: 688269:THETH_RS00575
uniprot id: F7YUN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

688269:THETH RS04940
gene id: 688269:THETH_RS04940
uniprot id: F7YYM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

688269:THETH RS00860
gene id: 688269:THETH_RS00860
uniprot id: F7YUT4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

688269:THETH RS01025
gene id: 688269:THETH_RS01025
uniprot id: F7YV23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

688269:THETH RS05635
gene id: 688269:THETH_RS05635
uniprot id: F7YTH3
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS04450
gene id: 688269:THETH_RS04450
uniprot id: F7YX58
names: Similarity
messages: Belongs to the MEMO1 family.

688269:THETH RS07925
gene id: 688269:THETH_RS07925
uniprot id: F7YU34
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

688269:THETH RS07790
gene id: 688269:THETH_RS07790
uniprot id: F7YU12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

688269:THETH RS05370
gene id: 688269:THETH_RS05370
uniprot id: F7YYU8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

688269:THETH RS09905
gene id: 688269:THETH_RS09905
uniprot id: F7YWL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

688269:THETH RS06335
gene id: 688269:THETH_RS06335
uniprot id: F7YUC5
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02675
gene id: 688269:THETH_RS02675
uniprot id: F7YXH9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

688269:THETH RS09500
gene id: 688269:THETH_RS09500
uniprot id: F7YWE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

688269:THETH RS05975
gene id: 688269:THETH_RS05975
uniprot id: F7YTM9
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

688269:THETH RS02155
gene id: 688269:THETH_RS02155
uniprot id: F7YW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

688269:THETH RS04900
gene id: 688269:THETH_RS04900
uniprot id: F7YYL8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

688269:THETH RS07895
gene id: 688269:THETH_RS07895
uniprot id: F7YXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

688269:THETH RS05655
gene id: 688269:THETH_RS05655
uniprot id: F7YTH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

688269:THETH RS00715
gene id: 688269:THETH_RS00715
uniprot id: F7YWS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS00870
gene id: 688269:THETH_RS00870
uniprot id: F7YUZ2
names: Similarity
messages: Belongs to the UPF0473 family.

688269:THETH RS00635
gene id: 688269:THETH_RS00635
uniprot id: F7YUP5
names: Similarity
messages: Belongs to the DtxR/MntR family.

688269:THETH RS07435
gene id: 688269:THETH_RS07435
uniprot id: F7YUW3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

688269:THETH RS09965
gene id: 688269:THETH_RS09965
uniprot id: F7YWM3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

688269:THETH RS07560
gene id: 688269:THETH_RS07560
uniprot id: F7YUY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

688269:THETH RS00825
gene id: 688269:THETH_RS00825
uniprot id: F7YUS9
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS09850
gene id: 688269:THETH_RS09850
uniprot id: F7YWK5
names: Similarity
messages: Belongs to the peptidase U62 family.

688269:THETH RS03995
gene id: 688269:THETH_RS03995
uniprot id: F7YY58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

688269:THETH RS09435
gene id: 688269:THETH_RS09435
uniprot id: F7YWD5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

688269:THETH RS08500
gene id: 688269:THETH_RS08500
uniprot id: F7YXE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

688269:THETH RS05195
gene id: 688269:THETH_RS05195
uniprot id: F7YYR9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

688269:THETH RS09430
gene id: 688269:THETH_RS09430
uniprot id: F7YWD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

688269:THETH RS09640
gene id: 688269:THETH_RS09640
uniprot id: F7YWH0
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS03730
gene id: 688269:THETH_RS03730
uniprot id: F7YY14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

688269:THETH RS00060
gene id: 688269:THETH_RS00060
uniprot id: F7YTE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

688269:THETH RS10200
gene id: 688269:THETH_RS10200
uniprot id: F7YWR3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

688269:THETH RS01290
gene id: 688269:THETH_RS01290
uniprot id: F7YV58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

688269:THETH RS01680
gene id: 688269:THETH_RS01680
uniprot id: F7YVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

688269:THETH RS03050
gene id: 688269:THETH_RS03050
uniprot id: F7YXP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS00725
gene id: 688269:THETH_RS00725
uniprot id: F7YUR2
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

688269:THETH RS04090
gene id: 688269:THETH_RS04090
uniprot id: F7YX54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

688269:THETH RS01940
gene id: 688269:THETH_RS01940
uniprot id: F7YVH2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS07765
gene id: 688269:THETH_RS07765
uniprot id: F7YU07
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

688269:THETH RS01235
gene id: 688269:THETH_RS01235
uniprot id: F7YV48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS01390
gene id: 688269:THETH_RS01390
uniprot id: F7YV81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

688269:THETH RS00015
gene id: 688269:THETH_RS00015
uniprot id: F7YTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

688269:THETH RS06650
gene id: 688269:THETH_RS06650
uniprot id: F7YTT3
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

688269:THETH RS02355
gene id: 688269:THETH_RS02355
uniprot id: F7YWW7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

688269:THETH RS01205
gene id: 688269:THETH_RS01205
uniprot id: F7YV43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

688269:THETH RS08270
gene id: 688269:THETH_RS08270
uniprot id: F7YVM7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

688269:THETH RS03760
gene id: 688269:THETH_RS03760
uniprot id: F7YY20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

688269:THETH RS03470
gene id: 688269:THETH_RS03470
uniprot id: F7YXX2
names: Subcellular Location Annotation
messages: Cytoplasm

688269:THETH RS02580
gene id: 688269:THETH_RS02580
uniprot id: F7YX06
names: Similarity
messages: Belongs to the UPF0047 family.

688269:THETH RS00620
gene id: 688269:THETH_RS00620
uniprot id: F7YUP2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

688269:THETH RS01870
gene id: 688269:THETH_RS01870
uniprot id: F7YWV1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

688269:THETH RS07360
gene id: 688269:THETH_RS07360
uniprot id: F7YUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

688269:THETH RS04405
gene id: 688269:THETH_RS04405
uniprot id: F7YYD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

688269:THETH RS06980
gene id: 688269:THETH_RS06980
uniprot id: F7YUG7
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02235
gene id: 688269:THETH_RS02235
uniprot id: F7YW50
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

688269:THETH RS01740
gene id: 688269:THETH_RS01740
uniprot id: F7YVE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

688269:THETH RS06585
gene id: 688269:THETH_RS06585
uniprot id: F7YTS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

688269:THETH RS09820
gene id: 688269:THETH_RS09820
uniprot id: F7YWK1
names: Similarity
messages: Belongs to the UPF0145 family.

688269:THETH RS04570
gene id: 688269:THETH_RS04570
uniprot id: F7YYG2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

688269:THETH RS09505
gene id: 688269:THETH_RS09505
uniprot id: F7YWE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

688269:THETH RS05295
gene id: 688269:THETH_RS05295
uniprot id: F7YYT6
names: Similarity
messages: Belongs to the TlyA family.
messages: Belongs to the universal ribosomal protein uS4 family.

688269:THETH RS04305
gene id: 688269:THETH_RS04305
uniprot id: F7YYB3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

688269:THETH RS04390
gene id: 688269:THETH_RS04390
uniprot id: F7YYC7
names: Similarity
messages: Belongs to the peptidase U62 family.

688269:THETH RS04005
gene id: 688269:THETH_RS04005
uniprot id: F7YY60
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

688269:THETH RS08845
gene id: 688269:THETH_RS08845
uniprot id: F7YXF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

688269:THETH RS05735
gene id: 688269:THETH_RS05735
uniprot id: F7YTJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

688269:THETH RS04985
gene id: 688269:THETH_RS04985
uniprot id: F7YYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

688269:THETH RS03165
gene id: 688269:THETH_RS03165
uniprot id: F7YXS0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

688269:THETH RS04565
gene id: 688269:THETH_RS04565
uniprot id: F7YYG1
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

688269:THETH RS00230
gene id: 688269:THETH_RS00230
uniprot id: F7YU54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

688269:THETH RS05360
gene id: 688269:THETH_RS05360
uniprot id: F7YX75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

688269:THETH RS01265
gene id: 688269:THETH_RS01265
uniprot id: F7YV53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

688269:THETH RS03990
gene id: 688269:THETH_RS03990
uniprot id: F7YY57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

688269:THETH RS03320
gene id: 688269:THETH_RS03320
uniprot id: F7YX32
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS00905
gene id: 688269:THETH_RS00905
uniprot id: F7YUZ9
names: Similarity
messages: Belongs to the histone deacetylase family.

688269:THETH RS06235
gene id: 688269:THETH_RS06235
uniprot id: F7YUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

688269:THETH RS04240
gene id: 688269:THETH_RS04240
uniprot id: F7YYA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

688269:THETH RS00290
gene id: 688269:THETH_RS00290
uniprot id: F7YU66
names: Similarity
messages: Belongs to the RemA family.

688269:THETH RS04955
gene id: 688269:THETH_RS04955
uniprot id: F7YYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

688269:THETH RS05570
gene id: 688269:THETH_RS05570
uniprot id: F7YTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS05470
gene id: 688269:THETH_RS05470
uniprot id: F7YYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

688269:THETH RS00095
gene id: 688269:THETH_RS00095
uniprot id: F7YTE8
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS10290
gene id: 688269:THETH_RS10290
uniprot id: F7YYD7
names: Similarity
messages: Belongs to the bacterial secretin family.

688269:THETH RS00175
gene id: 688269:THETH_RS00175
uniprot id: F7YU44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

688269:THETH RS03315
gene id: 688269:THETH_RS03315
uniprot id: F7YXU7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

688269:THETH RS03375
gene id: 688269:THETH_RS03375
uniprot id: F7YXV4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS03715
gene id: 688269:THETH_RS03715
uniprot id: F7YY11
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

688269:THETH RS05690
gene id: 688269:THETH_RS05690
uniprot id: F7YTI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

688269:THETH RS09135
gene id: 688269:THETH_RS09135
uniprot id: F7YW86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

688269:THETH RS06340
gene id: 688269:THETH_RS06340
uniprot id: F7YUC6
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS08575
gene id: 688269:THETH_RS08575
uniprot id: F7YVT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

688269:THETH RS03530
gene id: 688269:THETH_RS03530
uniprot id: F7YXY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Role in flagellar biosynthesis.

688269:THETH RS09685
gene id: 688269:THETH_RS09685
uniprot id: F7YXG4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

688269:THETH RS04615
gene id: 688269:THETH_RS04615
uniprot id: F7YYH0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

688269:THETH RS05430
gene id: 688269:THETH_RS05430
uniprot id: F7YYV8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

688269:THETH RS02300
gene id: 688269:THETH_RS02300
uniprot id: F7YWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

688269:THETH RS10115
gene id: 688269:THETH_RS10115
uniprot id: F7YWP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

688269:THETH RS09170
gene id: 688269:THETH_RS09170
uniprot id: F7YW93
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

688269:THETH RS04705
gene id: 688269:THETH_RS04705
uniprot id: F7YYI3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

688269:THETH RS02205
gene id: 688269:THETH_RS02205
uniprot id: F7YW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

688269:THETH RS00180
gene id: 688269:THETH_RS00180
uniprot id: F7YU45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

688269:THETH RS03540
gene id: 688269:THETH_RS03540
uniprot id: F7YXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

688269:THETH RS01285
gene id: 688269:THETH_RS01285
uniprot id: F7YV57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS09085
gene id: 688269:THETH_RS09085
uniprot id: F7YW76
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

688269:THETH RS01575
gene id: 688269:THETH_RS01575
uniprot id: F7YVB0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

688269:THETH RS07390
gene id: 688269:THETH_RS07390
uniprot id: F7YUV4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

688269:THETH RS03115
gene id: 688269:THETH_RS03115
uniprot id: F7YXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS03160
gene id: 688269:THETH_RS03160
uniprot id: F7YXR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

688269:THETH RS00795
gene id: 688269:THETH_RS00795
uniprot id: F7YUS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

688269:THETH RS00030
gene id: 688269:THETH_RS00030
uniprot id: F7YTD5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS07780
gene id: 688269:THETH_RS07780
uniprot id: F7YU10
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS01935
gene id: 688269:THETH_RS01935
uniprot id: F7YWV4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

688269:THETH RS07945
gene id: 688269:THETH_RS07945
uniprot id: F7YU37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

688269:THETH RS02585
gene id: 688269:THETH_RS02585
uniprot id: F7YX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

688269:THETH RS04075
gene id: 688269:THETH_RS04075
uniprot id: F7YY70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS10140
gene id: 688269:THETH_RS10140
uniprot id: F7YWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

688269:THETH RS03820
gene id: 688269:THETH_RS03820
uniprot id: F7YY32
names: Similarity
messages: Belongs to the UPF0111 family.

688269:THETH RS05060
gene id: 688269:THETH_RS05060
uniprot id: F7YYP8
names: Similarity
messages: Belongs to the FGGY kinase family.

688269:THETH RS03860
gene id: 688269:THETH_RS03860
uniprot id: F7YY39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

688269:THETH RS05515
gene id: 688269:THETH_RS05515
uniprot id: F7YYX3
names: Similarity
messages: Belongs to the creatininase superfamily.

688269:THETH RS04750
gene id: 688269:THETH_RS04750
uniprot id: F7YX64
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

688269:THETH RS09660
gene id: 688269:THETH_RS09660
uniprot id: F7YWH4
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

688269:THETH RS07660
gene id: 688269:THETH_RS07660
uniprot id: F7YTY6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS02075
gene id: 688269:THETH_RS02075
uniprot id: F7YW18
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02045
gene id: 688269:THETH_RS02045
uniprot id: F7YW16
names: Similarity
messages: Belongs to the class-I fumarase family.

688269:THETH RS00790
gene id: 688269:THETH_RS00790
uniprot id: F7YUS4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

688269:THETH RS05900
gene id: 688269:THETH_RS05900
uniprot id: F7YTL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

688269:THETH RS08225
gene id: 688269:THETH_RS08225
uniprot id: F7YVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS04440
gene id: 688269:THETH_RS04440
uniprot id: F7YYD5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

688269:THETH RS09495
gene id: 688269:THETH_RS09495
uniprot id: F7YWE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

688269:THETH RS05965
gene id: 688269:THETH_RS05965
uniprot id: F7YTM7
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

688269:THETH RS00935
gene id: 688269:THETH_RS00935
uniprot id: F7YV05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS06515
gene id: 688269:THETH_RS06515
uniprot id: F7YUF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

688269:THETH RS02760
gene id: 688269:THETH_RS02760
uniprot id: F7YXJ6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

688269:THETH RS05475
gene id: 688269:THETH_RS05475
uniprot id: F7YYW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

688269:THETH RS07990
gene id: 688269:THETH_RS07990
uniprot id: F7YVI0
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

688269:THETH RS01510
gene id: 688269:THETH_RS01510
uniprot id: F7YVA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

688269:THETH RS00245
gene id: 688269:THETH_RS00245
uniprot id: F7YU57
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

688269:THETH RS01560
gene id: 688269:THETH_RS01560
uniprot id: F7YVA7
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

688269:THETH RS02455
gene id: 688269:THETH_RS02455
uniprot id: F7YWY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

688269:THETH RS05985
gene id: 688269:THETH_RS05985
uniprot id: F7YTN1
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

688269:THETH RS00410
gene id: 688269:THETH_RS00410
uniprot id: F7YU88
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

688269:THETH RS10155
gene id: 688269:THETH_RS10155
uniprot id: F7YWQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

688269:THETH RS05305
gene id: 688269:THETH_RS05305
uniprot id: F7YYT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS00010
gene id: 688269:THETH_RS00010
uniprot id: F7YTD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

688269:THETH RS00300
gene id: 688269:THETH_RS00300
uniprot id: F7YU68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

688269:THETH RS04780
gene id: 688269:THETH_RS04780
uniprot id: F7YYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

688269:THETH RS03865
gene id: 688269:THETH_RS03865
uniprot id: F7YY40
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

688269:THETH RS04855
gene id: 688269:THETH_RS04855
uniprot id: F7YYK9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

688269:THETH RS01500
gene id: 688269:THETH_RS01500
uniprot id: F7YV99
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS08860
gene id: 688269:THETH_RS08860
uniprot id: F7YVX9
names: Similarity
messages: Belongs to the UxaA family.

688269:THETH RS05250
gene id: 688269:THETH_RS05250
uniprot id: F7YYT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

688269:THETH RS04825
gene id: 688269:THETH_RS04825
uniprot id: F7YYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS07810
gene id: 688269:THETH_RS07810
uniprot id: F7YXC3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

688269:THETH RS10055
gene id: 688269:THETH_RS10055
uniprot id: F7YWN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

688269:THETH RS01020
gene id: 688269:THETH_RS01020
uniprot id: F7YV22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

688269:THETH RS09305
gene id: 688269:THETH_RS09305
uniprot id: F7YXG0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

688269:THETH RS09110
gene id: 688269:THETH_RS09110
uniprot id: F7YW81
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

688269:THETH RS06315
gene id: 688269:THETH_RS06315
uniprot id: F7YUC1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

688269:THETH RS04290
gene id: 688269:THETH_RS04290
uniprot id: F7YYB0
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS10080
gene id: 688269:THETH_RS10080
uniprot id: F7YWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

688269:THETH RS03745
gene id: 688269:THETH_RS03745
uniprot id: F7YY17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

688269:THETH RS09480
gene id: 688269:THETH_RS09480
uniprot id: F7YWE4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS09545
gene id: 688269:THETH_RS09545
uniprot id: F7YWF7
names: Subcellular Location Annotation
messages: Cytoplasm

688269:THETH RS00240
gene id: 688269:THETH_RS00240
uniprot id: F7YU56
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

688269:THETH RS04260
gene id: 688269:THETH_RS04260
uniprot id: F7YYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

688269:THETH RS07045
gene id: 688269:THETH_RS07045
uniprot id: F7YUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS03085
gene id: 688269:THETH_RS03085
uniprot id: F7YXQ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS00710
gene id: 688269:THETH_RS00710
uniprot id: F7YUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS06675
gene id: 688269:THETH_RS06675
uniprot id: F7YTT8
names: Similarity
messages: Belongs to the peptidase C40 family.

688269:THETH RS07680
gene id: 688269:THETH_RS07680
uniprot id: F7YTZ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS09450
gene id: 688269:THETH_RS09450
uniprot id: F7YWD8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

688269:THETH RS01535
gene id: 688269:THETH_RS01535
uniprot id: F7YVA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

688269:THETH RS05880
gene id: 688269:THETH_RS05880
uniprot id: F7YTK9
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

688269:THETH RS05180
gene id: 688269:THETH_RS05180
uniprot id: F7YYR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

688269:THETH RS03005
gene id: 688269:THETH_RS03005
uniprot id: F7YXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

688269:THETH RS02690
gene id: 688269:THETH_RS02690
uniprot id: F7YXI2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

688269:THETH RS09320
gene id: 688269:THETH_RS09320
uniprot id: F7YXG1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

688269:THETH RS09055
gene id: 688269:THETH_RS09055
uniprot id: F7YW70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

688269:THETH RS02810
gene id: 688269:THETH_RS02810
uniprot id: F7YXK6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

688269:THETH RS08645
gene id: 688269:THETH_RS08645
uniprot id: F7YVU3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

688269:THETH RS06385
gene id: 688269:THETH_RS06385
uniprot id: F7YUD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

688269:THETH RS05955
gene id: 688269:THETH_RS05955
uniprot id: F7YTM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

688269:THETH RS06840
gene id: 688269:THETH_RS06840
uniprot id: F7YXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

688269:THETH RS05320
gene id: 688269:THETH_RS05320
uniprot id: F7YYU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

688269:THETH RS08400
gene id: 688269:THETH_RS08400
uniprot id: F7YVQ2
names: Similarity
messages: Belongs to the GSP E family.

688269:THETH RS07695
gene id: 688269:THETH_RS07695
uniprot id: F7YTZ3
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS07870
gene id: 688269:THETH_RS07870
uniprot id: F7YU25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS05715
gene id: 688269:THETH_RS05715
uniprot id: F7YTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS03140
gene id: 688269:THETH_RS03140
uniprot id: F7YXR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

688269:THETH RS02535
gene id: 688269:THETH_RS02535
uniprot id: F7YX00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

688269:THETH RS03645
gene id: 688269:THETH_RS03645
uniprot id: F7YY02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

688269:THETH RS09945
gene id: 688269:THETH_RS09945
uniprot id: F7YWM1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

688269:THETH RS08420
gene id: 688269:THETH_RS08420
uniprot id: F7YVQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

688269:THETH RS02195
gene id: 688269:THETH_RS02195
uniprot id: F7YW42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

688269:THETH RS07940
gene id: 688269:THETH_RS07940
uniprot id: F7YU36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS01370
gene id: 688269:THETH_RS01370
uniprot id: F7YV77
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS10065
gene id: 688269:THETH_RS10065
uniprot id: F7YWN9
names: Similarity
messages: Belongs to the asp23 family.

688269:THETH RS09675
gene id: 688269:THETH_RS09675
uniprot id: F7YWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

688269:THETH RS07535
gene id: 688269:THETH_RS07535
uniprot id: F7YUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

688269:THETH RS02125
gene id: 688269:THETH_RS02125
uniprot id: F7YW30
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

688269:THETH RS09595
gene id: 688269:THETH_RS09595
uniprot id: F7YWG1
names: Similarity
messages: Belongs to the serpin family.

688269:THETH RS00850
gene id: 688269:THETH_RS00850
uniprot id: F7YWS6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

688269:THETH RS03675
gene id: 688269:THETH_RS03675
uniprot id: F7YX41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

688269:THETH RS03665
gene id: 688269:THETH_RS03665
uniprot id: F7YX40
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

688269:THETH RS02110
gene id: 688269:THETH_RS02110
uniprot id: F7YW25
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

688269:THETH RS00985
gene id: 688269:THETH_RS00985
uniprot id: F7YV15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS01030
gene id: 688269:THETH_RS01030
uniprot id: F7YWS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

688269:THETH RS03635
gene id: 688269:THETH_RS03635
uniprot id: F7YX39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

688269:THETH RS00975
gene id: 688269:THETH_RS00975
uniprot id: F7YV13
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS04275
gene id: 688269:THETH_RS04275
uniprot id: F7YYA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

688269:THETH RS05410
gene id: 688269:THETH_RS05410
uniprot id: F7YYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

688269:THETH RS06655
gene id: 688269:THETH_RS06655
uniprot id: F7YTT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

688269:THETH RS01520
gene id: 688269:THETH_RS01520
uniprot id: F7YVA1
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

688269:THETH RS03685
gene id: 688269:THETH_RS03685
uniprot id: F7YX42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

688269:THETH RS05685
gene id: 688269:THETH_RS05685
uniprot id: F7YTI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

688269:THETH RS00785
gene id: 688269:THETH_RS00785
uniprot id: F7YUS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

688269:THETH RS02835
gene id: 688269:THETH_RS02835
uniprot id: F7YXL1
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

688269:THETH RS07410
gene id: 688269:THETH_RS07410
uniprot id: F7YUV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

688269:THETH RS05280
gene id: 688269:THETH_RS05280
uniprot id: F7YYT3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

688269:THETH RS10160
gene id: 688269:THETH_RS10160
uniprot id: F7YWQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

688269:THETH RS09130
gene id: 688269:THETH_RS09130
uniprot id: F7YW85
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

688269:THETH RS01825
gene id: 688269:THETH_RS01825
uniprot id: F7YVF6
names: Similarity
messages: Belongs to the IMPACT family.

688269:THETH RS06105
gene id: 688269:THETH_RS06105
uniprot id: F7YX91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

688269:THETH RS00125
gene id: 688269:THETH_RS00125
uniprot id: F7YTF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS00890
gene id: 688269:THETH_RS00890
uniprot id: F7YUZ6
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS08735
gene id: 688269:THETH_RS08735
uniprot id: F7YVW0
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS01415
gene id: 688269:THETH_RS01415
uniprot id: F7YV86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

688269:THETH RS01360
gene id: 688269:THETH_RS01360
uniprot id: F7YV74
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

688269:THETH RS00990
gene id: 688269:THETH_RS00990
uniprot id: F7YV16
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS07805
gene id: 688269:THETH_RS07805
uniprot id: F7YU15
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

688269:THETH RS02985
gene id: 688269:THETH_RS02985
uniprot id: F7YXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

688269:THETH RS03175
gene id: 688269:THETH_RS03175
uniprot id: F7YXS2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

688269:THETH RS06735
gene id: 688269:THETH_RS06735
uniprot id: F7YTU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

688269:THETH RS03465
gene id: 688269:THETH_RS03465
uniprot id: F7YXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS02400
gene id: 688269:THETH_RS02400
uniprot id: F7YWX6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

688269:THETH RS07705
gene id: 688269:THETH_RS07705
uniprot id: F7YTZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

688269:THETH RS01570
gene id: 688269:THETH_RS01570
uniprot id: F7YVA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS04360
gene id: 688269:THETH_RS04360
uniprot id: F7YYC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

688269:THETH RS02670
gene id: 688269:THETH_RS02670
uniprot id: F7YXH8
names: Similarity
messages: Belongs to the aspartokinase family.

688269:THETH RS05895
gene id: 688269:THETH_RS05895
uniprot id: F7YTL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

688269:THETH RS10635
gene id: 688269:THETH_RS10635
uniprot id: F7YWP2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

688269:THETH RS02325
gene id: 688269:THETH_RS02325
uniprot id: F7YWW2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS03740
gene id: 688269:THETH_RS03740
uniprot id: F7YY16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

688269:THETH RS03480
gene id: 688269:THETH_RS03480
uniprot id: F7YXX4
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS07960
gene id: 688269:THETH_RS07960
uniprot id: F7YVH4
names: Similarity
messages: Belongs to the asp23 family.

688269:THETH RS05765
gene id: 688269:THETH_RS05765
uniprot id: F7YTJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS07270
gene id: 688269:THETH_RS07270
uniprot id: F7YXB3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

688269:THETH RS05670
gene id: 688269:THETH_RS05670
uniprot id: F7YTI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS04740
gene id: 688269:THETH_RS04740
uniprot id: F7YYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

688269:THETH RS02220
gene id: 688269:THETH_RS02220
uniprot id: F7YW47
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

688269:THETH RS05450
gene id: 688269:THETH_RS05450
uniprot id: F7YYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

688269:THETH RS00915
gene id: 688269:THETH_RS00915
uniprot id: F7YV01
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

688269:THETH RS04635
gene id: 688269:THETH_RS04635
uniprot id: F7YX60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS09095
gene id: 688269:THETH_RS09095
uniprot id: F7YW78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS01000
gene id: 688269:THETH_RS01000
uniprot id: F7YV18
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

688269:THETH RS05225
gene id: 688269:THETH_RS05225
uniprot id: F7YYS5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

688269:THETH RS00925
gene id: 688269:THETH_RS00925
uniprot id: F7YV03
names: Similarity
messages: Belongs to the archease family.

688269:THETH RS10070
gene id: 688269:THETH_RS10070
uniprot id: F7YXH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

688269:THETH RS10335
gene id: 688269:THETH_RS10335
uniprot id: F7YUG9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

688269:THETH RS03070
gene id: 688269:THETH_RS03070
uniprot id: F7YXQ2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

688269:THETH RS06260
gene id: 688269:THETH_RS06260
uniprot id: F7YUA9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

688269:THETH RS08940
gene id: 688269:THETH_RS08940
uniprot id: F7YVZ1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS10400
gene id: 688269:THETH_RS10400
uniprot id: F7YVT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

688269:THETH RS04380
gene id: 688269:THETH_RS04380
uniprot id: F7YYC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

688269:THETH RS04220
gene id: 688269:THETH_RS04220
uniprot id: F7YY96
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

688269:THETH RS10315
gene id: 688269:THETH_RS10315
uniprot id: F7YTN8
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS06380
gene id: 688269:THETH_RS06380
uniprot id: F7YUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

688269:THETH RS01400
gene id: 688269:THETH_RS01400
uniprot id: F7YV83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

688269:THETH RS09790
gene id: 688269:THETH_RS09790
uniprot id: F7YWJ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

688269:THETH RS06830
gene id: 688269:THETH_RS06830
uniprot id: F7YXA4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

688269:THETH RS02210
gene id: 688269:THETH_RS02210
uniprot id: F7YW45
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

688269:THETH RS04655
gene id: 688269:THETH_RS04655
uniprot id: F7YYH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

688269:THETH RS00285
gene id: 688269:THETH_RS00285
uniprot id: F7YU65
names: Similarity
messages: Belongs to the YicC/YloC family.

688269:THETH RS04250
gene id: 688269:THETH_RS04250
uniprot id: F7YYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

688269:THETH RS07815
gene id: 688269:THETH_RS07815
uniprot id: F7YU16
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS02035
gene id: 688269:THETH_RS02035
uniprot id: F7YW14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

688269:THETH RS09245
gene id: 688269:THETH_RS09245
uniprot id: F7YXF9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

688269:THETH RS00610
gene id: 688269:THETH_RS00610
uniprot id: F7YUP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

688269:THETH RS09940
gene id: 688269:THETH_RS09940
uniprot id: F7YWM0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

688269:THETH RS09805
gene id: 688269:THETH_RS09805
uniprot id: F7YWJ8
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS04345
gene id: 688269:THETH_RS04345
uniprot id: F7YYB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

688269:THETH RS06445
gene id: 688269:THETH_RS06445
uniprot id: F7YUE3
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS07740
gene id: 688269:THETH_RS07740
uniprot id: F7YU02
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS00400
gene id: 688269:THETH_RS00400
uniprot id: F7YU86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

688269:THETH RS05405
gene id: 688269:THETH_RS05405
uniprot id: F7YYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

688269:THETH RS05270
gene id: 688269:THETH_RS05270
uniprot id: F7YYT1
names: Function
names: Subunit
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.

688269:THETH RS10295
gene id: 688269:THETH_RS10295
uniprot id: F7YX66
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

688269:THETH RS10145
gene id: 688269:THETH_RS10145
uniprot id: F7YWQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS06525
gene id: 688269:THETH_RS06525
uniprot id: F7YUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

688269:THETH RS07985
gene id: 688269:THETH_RS07985
uniprot id: F7YVH9
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

688269:THETH RS04355
gene id: 688269:THETH_RS04355
uniprot id: F7YYC0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

688269:THETH RS01640
gene id: 688269:THETH_RS01640
uniprot id: F7YVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS09225
gene id: 688269:THETH_RS09225
uniprot id: F7YWA3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

688269:THETH RS02330
gene id: 688269:THETH_RS02330
uniprot id: F7YWW3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

688269:THETH RS02890
gene id: 688269:THETH_RS02890
uniprot id: F7YXL9
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

688269:THETH RS08005
gene id: 688269:THETH_RS08005
uniprot id: F7YVI3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

688269:THETH RS03105
gene id: 688269:THETH_RS03105
uniprot id: F7YXQ9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

688269:THETH RS09250
gene id: 688269:THETH_RS09250
uniprot id: F7YWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

688269:THETH RS04590
gene id: 688269:THETH_RS04590
uniprot id: F7YYG6
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02770
gene id: 688269:THETH_RS02770
uniprot id: F7YXJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS01815
gene id: 688269:THETH_RS01815
uniprot id: F7YVF4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

688269:THETH RS01660
gene id: 688269:THETH_RS01660
uniprot id: F7YVC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

688269:THETH RS09935
gene id: 688269:THETH_RS09935
uniprot id: F7YXG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

688269:THETH RS02625
gene id: 688269:THETH_RS02625
uniprot id: F7YX13
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

688269:THETH RS04425
gene id: 688269:THETH_RS04425
uniprot id: F7YX57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

688269:THETH RS06535
gene id: 688269:THETH_RS06535
uniprot id: F7YUF6
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

688269:THETH RS05545
gene id: 688269:THETH_RS05545
uniprot id: F7YTF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS04035
gene id: 688269:THETH_RS04035
uniprot id: F7YX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS08775
gene id: 688269:THETH_RS08775
uniprot id: F7YVW8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

688269:THETH RS01330
gene id: 688269:THETH_RS01330
uniprot id: F7YV68
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

688269:THETH RS10120
gene id: 688269:THETH_RS10120
uniprot id: F7YWP8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

688269:THETH RS02415
gene id: 688269:THETH_RS02415
uniprot id: F7YWX9
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS10075
gene id: 688269:THETH_RS10075
uniprot id: F7YWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

688269:THETH RS04970
gene id: 688269:THETH_RS04970
uniprot id: F7YYN3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

688269:THETH RS02470
gene id: 688269:THETH_RS02470
uniprot id: F7YWY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

688269:THETH RS07890
gene id: 688269:THETH_RS07890
uniprot id: F7YU28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

688269:THETH RS02160
gene id: 688269:THETH_RS02160
uniprot id: F7YX19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

688269:THETH RS04775
gene id: 688269:THETH_RS04775
uniprot id: F7YYJ5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

688269:THETH RS01955
gene id: 688269:THETH_RS01955
uniprot id: F7YW00
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

688269:THETH RS09035
gene id: 688269:THETH_RS09035
uniprot id: F7YW66
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

688269:THETH RS08185
gene id: 688269:THETH_RS08185
uniprot id: F7YVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS00130
gene id: 688269:THETH_RS00130
uniprot id: F7YTF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS08455
gene id: 688269:THETH_RS08455
uniprot id: F7YVR2
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS04375
gene id: 688269:THETH_RS04375
uniprot id: F7YYC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

688269:THETH RS07980
gene id: 688269:THETH_RS07980
uniprot id: F7YVH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

688269:THETH RS07620
gene id: 688269:THETH_RS07620
uniprot id: F7YTX8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

688269:THETH RS00920
gene id: 688269:THETH_RS00920
uniprot id: F7YV02
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

688269:THETH RS08835
gene id: 688269:THETH_RS08835
uniprot id: F7YXF0
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS01785
gene id: 688269:THETH_RS01785
uniprot id: F7YVF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

688269:THETH RS00355
gene id: 688269:THETH_RS00355
uniprot id: F7YU79
names: Similarity
messages: Belongs to the FGGY kinase family.

688269:THETH RS03755
gene id: 688269:THETH_RS03755
uniprot id: F7YY19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

688269:THETH RS03785
gene id: 688269:THETH_RS03785
uniprot id: F7YY25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS10640
gene id: 688269:THETH_RS10640
uniprot id: F7YWP3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

688269:THETH RS08415
gene id: 688269:THETH_RS08415
uniprot id: F7YVQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

688269:THETH RS02755
gene id: 688269:THETH_RS02755
uniprot id: F7YXJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

688269:THETH RS07430
gene id: 688269:THETH_RS07430
uniprot id: F7YUW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS09125
gene id: 688269:THETH_RS09125
uniprot id: F7YW84
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS09975
gene id: 688269:THETH_RS09975
uniprot id: F7YWM5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

688269:THETH RS03390
gene id: 688269:THETH_RS03390
uniprot id: F7YXV7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

688269:THETH RS09855
gene id: 688269:THETH_RS09855
uniprot id: F7YWK6
names: Similarity
messages: Belongs to the peptidase U62 family.

688269:THETH RS04665
gene id: 688269:THETH_RS04665
uniprot id: F7YYH7
names: Similarity
messages: Belongs to the methyltransferase superfamily. PrmA family.

688269:THETH RS09415
gene id: 688269:THETH_RS09415
uniprot id: F7YWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS06310
gene id: 688269:THETH_RS06310
uniprot id: F7YUC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

688269:THETH RS03490
gene id: 688269:THETH_RS03490
uniprot id: F7YXX6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

688269:THETH RS03415
gene id: 688269:THETH_RS03415
uniprot id: F7YXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

688269:THETH RS08045
gene id: 688269:THETH_RS08045
uniprot id: F7YVJ0
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

688269:THETH RS06975
gene id: 688269:THETH_RS06975
uniprot id: F7YUG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS03650
gene id: 688269:THETH_RS03650
uniprot id: F7YY03
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

688269:THETH RS03620
gene id: 688269:THETH_RS03620
uniprot id: F7YXZ8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

688269:THETH RS08720
gene id: 688269:THETH_RS08720
uniprot id: F7YVV7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

688269:THETH RS05175
gene id: 688269:THETH_RS05175
uniprot id: F7YYR5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

688269:THETH RS07735
gene id: 688269:THETH_RS07735
uniprot id: F7YU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

688269:THETH RS01665
gene id: 688269:THETH_RS01665
uniprot id: F7YVC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS08525
gene id: 688269:THETH_RS08525
uniprot id: F7YVS3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

688269:THETH RS08375
gene id: 688269:THETH_RS08375
uniprot id: F7YVP7
names: Similarity
messages: Belongs to the peptidase C69 family.

688269:THETH RS05345
gene id: 688269:THETH_RS05345
uniprot id: F7YX74
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

688269:THETH RS08625
gene id: 688269:THETH_RS08625
uniprot id: F7YVT9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS09865
gene id: 688269:THETH_RS09865
uniprot id: F7YWK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

688269:THETH RS08250
gene id: 688269:THETH_RS08250
uniprot id: F7YXD7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

688269:THETH RS06520
gene id: 688269:THETH_RS06520
uniprot id: F7YUF4
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

688269:THETH RS01395
gene id: 688269:THETH_RS01395
uniprot id: F7YV82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

688269:THETH RS04485
gene id: 688269:THETH_RS04485
uniprot id: F7YYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

688269:THETH RS07965
gene id: 688269:THETH_RS07965
uniprot id: F7YVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

688269:THETH RS01920
gene id: 688269:THETH_RS01920
uniprot id: F7YVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

688269:THETH RS03725
gene id: 688269:THETH_RS03725
uniprot id: F7YY13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

688269:THETH RS03520
gene id: 688269:THETH_RS03520
uniprot id: F7YXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

688269:THETH RS06910
gene id: 688269:THETH_RS06910
uniprot id: F7YXA7
names: Similarity
messages: Belongs to the intimin/invasin family.

688269:THETH RS01085
gene id: 688269:THETH_RS01085
uniprot id: F7YV29
names: Similarity
messages: Belongs to the peptidase M18 family.

688269:THETH RS08505
gene id: 688269:THETH_RS08505
uniprot id: F7YVS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

688269:THETH RS06180
gene id: 688269:THETH_RS06180
uniprot id: F7YTR3
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS06075
gene id: 688269:THETH_RS06075
uniprot id: F7YX88
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

688269:THETH RS06835
gene id: 688269:THETH_RS06835
uniprot id: F7YTW0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

688269:THETH RS07915
gene id: 688269:THETH_RS07915
uniprot id: F7YU32
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

688269:THETH RS02305
gene id: 688269:THETH_RS02305
uniprot id: F7YWV8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

688269:THETH RS08285
gene id: 688269:THETH_RS08285
uniprot id: F7YVM9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

688269:THETH RS03055
gene id: 688269:THETH_RS03055
uniprot id: F7YXP9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

688269:THETH RS08555
gene id: 688269:THETH_RS08555
uniprot id: F7YVS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS03720
gene id: 688269:THETH_RS03720
uniprot id: F7YY12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

688269:THETH RS01700
gene id: 688269:THETH_RS01700
uniprot id: F7YVD4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

688269:THETH RS00770
gene id: 688269:THETH_RS00770
uniprot id: F7YUS0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

688269:THETH RS09065
gene id: 688269:THETH_RS09065
uniprot id: F7YW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

688269:THETH RS01765
gene id: 688269:THETH_RS01765
uniprot id: F7YVE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

688269:THETH RS02005
gene id: 688269:THETH_RS02005
uniprot id: F7YW08
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

688269:THETH RS04055
gene id: 688269:THETH_RS04055
uniprot id: F7YX51
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

688269:THETH RS00320
gene id: 688269:THETH_RS00320
uniprot id: F7YU72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

688269:THETH RS03180
gene id: 688269:THETH_RS03180
uniprot id: F7YXS3
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

688269:THETH RS06900
gene id: 688269:THETH_RS06900
uniprot id: F7YTX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

688269:THETH RS03025
gene id: 688269:THETH_RS03025
uniprot id: F7YXP4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

688269:THETH RS04560
gene id: 688269:THETH_RS04560
uniprot id: F7YYG0
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

688269:THETH RS04580
gene id: 688269:THETH_RS04580
uniprot id: F7YYG4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

688269:THETH RS10150
gene id: 688269:THETH_RS10150
uniprot id: F7YWQ3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

688269:THETH RS07835
gene id: 688269:THETH_RS07835
uniprot id: F7YU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS01995
gene id: 688269:THETH_RS01995
uniprot id: F7YW06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

688269:THETH RS02655
gene id: 688269:THETH_RS02655
uniprot id: F7YXH5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

688269:THETH RS08220
gene id: 688269:THETH_RS08220
uniprot id: F7YVM0
names: Similarity
messages: Belongs to the UPF0045 family.

688269:THETH RS01015
gene id: 688269:THETH_RS01015
uniprot id: F7YV21
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

688269:THETH RS00345
gene id: 688269:THETH_RS00345
uniprot id: F7YU77
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

688269:THETH RS09145
gene id: 688269:THETH_RS09145
uniprot id: F7YW88
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

688269:THETH RS05420
gene id: 688269:THETH_RS05420
uniprot id: F7YYV6
names: Similarity
messages: Belongs to the UPF0102 family.

688269:THETH RS03765
gene id: 688269:THETH_RS03765
uniprot id: F7YY21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

688269:THETH RS08675
gene id: 688269:THETH_RS08675
uniprot id: F7YVU8
names: Similarity
messages: Belongs to the glutamine synthetase family.

688269:THETH RS01185
gene id: 688269:THETH_RS01185
uniprot id: F7YV40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

688269:THETH RS06970
gene id: 688269:THETH_RS06970
uniprot id: F7YUG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

688269:THETH RS09045
gene id: 688269:THETH_RS09045
uniprot id: F7YW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

688269:THETH RS00170
gene id: 688269:THETH_RS00170
uniprot id: F7YU43
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS04150
gene id: 688269:THETH_RS04150
uniprot id: F7YY82
names: Similarity
messages: Belongs to the fabD family.

688269:THETH RS05100
gene id: 688269:THETH_RS05100
uniprot id: F7YYQ5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

688269:THETH RS03565
gene id: 688269:THETH_RS03565
uniprot id: F7YXZ1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

688269:THETH RS08755
gene id: 688269:THETH_RS08755
uniprot id: F7YVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

688269:THETH RS03780
gene id: 688269:THETH_RS03780
uniprot id: F7YY24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

688269:THETH RS09120
gene id: 688269:THETH_RS09120
uniprot id: F7YW83
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

688269:THETH RS08700
gene id: 688269:THETH_RS08700
uniprot id: F7YVV3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

688269:THETH RS07745
gene id: 688269:THETH_RS07745
uniprot id: F7YU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

688269:THETH RS09895
gene id: 688269:THETH_RS09895
uniprot id: F7YWL3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

688269:THETH RS06550
gene id: 688269:THETH_RS06550
uniprot id: F7YUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

688269:THETH RS08495
gene id: 688269:THETH_RS08495
uniprot id: F7YVR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

688269:THETH RS05380
gene id: 688269:THETH_RS05380
uniprot id: F7YYU9
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS01770
gene id: 688269:THETH_RS01770
uniprot id: F7YVE8
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02290
gene id: 688269:THETH_RS02290
uniprot id: F7YWV5
names: Caution
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS03460
gene id: 688269:THETH_RS03460
uniprot id: F7YXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS10125
gene id: 688269:THETH_RS10125
uniprot id: F7YWP9
names: Similarity
messages: Belongs to the CTP synthase family.

688269:THETH RS01930
gene id: 688269:THETH_RS01930
uniprot id: F7YVH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

688269:THETH RS00820
gene id: 688269:THETH_RS00820
uniprot id: F7YUS8
names: Similarity
messages: Belongs to the archaeal ATPase family.

688269:THETH RS08925
gene id: 688269:THETH_RS08925
uniprot id: F7YVY9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

688269:THETH RS09380
gene id: 688269:THETH_RS09380
uniprot id: F7YWC5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

688269:THETH RS08690
gene id: 688269:THETH_RS08690
uniprot id: F7YVV1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

688269:THETH RS03190
gene id: 688269:THETH_RS03190
uniprot id: F7YXS5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

688269:THETH RS05870
gene id: 688269:THETH_RS05870
uniprot id: F7YTK7
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

688269:THETH RS05785
gene id: 688269:THETH_RS05785
uniprot id: F7YTJ7
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS00070
gene id: 688269:THETH_RS00070
uniprot id: F7YTE3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

688269:THETH RS06275
gene id: 688269:THETH_RS06275
uniprot id: F7YUB2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

688269:THETH RS02485
gene id: 688269:THETH_RS02485
uniprot id: F7YWZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

688269:THETH RS02575
gene id: 688269:THETH_RS02575
uniprot id: F7YX22
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

688269:THETH RS00330
gene id: 688269:THETH_RS00330
uniprot id: F7YU74
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

688269:THETH RS07400
gene id: 688269:THETH_RS07400
uniprot id: F7YUV6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

688269:THETH RS02465
gene id: 688269:THETH_RS02465
uniprot id: F7YWY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

688269:THETH RS00195
gene id: 688269:THETH_RS00195
uniprot id: F7YU48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

688269:THETH RS07600
gene id: 688269:THETH_RS07600
uniprot id: F7YUY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS08680
gene id: 688269:THETH_RS08680
uniprot id: F7YVU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

688269:THETH RS08975
gene id: 688269:THETH_RS08975
uniprot id: F7YVZ6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

688269:THETH RS04895
gene id: 688269:THETH_RS04895
uniprot id: F7YYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

688269:THETH RS09395
gene id: 688269:THETH_RS09395
uniprot id: F7YWC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

688269:THETH RS00365
gene id: 688269:THETH_RS00365
uniprot id: F7YU81
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

688269:THETH RS09635
gene id: 688269:THETH_RS09635
uniprot id: F7YWG9
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02445
gene id: 688269:THETH_RS02445
uniprot id: F7YWY4
names: Similarity
messages: Belongs to the TrpF family.

688269:THETH RS01585
gene id: 688269:THETH_RS01585
uniprot id: F7YVB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

688269:THETH RS07920
gene id: 688269:THETH_RS07920
uniprot id: F7YU33
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

688269:THETH RS01375
gene id: 688269:THETH_RS01375
uniprot id: F7YV78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

688269:THETH RS08145
gene id: 688269:THETH_RS08145
uniprot id: F7YXD2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

688269:THETH RS00250
gene id: 688269:THETH_RS00250
uniprot id: F7YU58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

688269:THETH RS08670
gene id: 688269:THETH_RS08670
uniprot id: F7YVU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

688269:THETH RS07845
gene id: 688269:THETH_RS07845
uniprot id: F7YXC4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

688269:THETH RS02150
gene id: 688269:THETH_RS02150
uniprot id: F7YW34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

688269:THETH RS00080
gene id: 688269:THETH_RS00080
uniprot id: F7YTE5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

688269:THETH RS09030
gene id: 688269:THETH_RS09030
uniprot id: F7YW65
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

688269:THETH RS03200
gene id: 688269:THETH_RS03200
uniprot id: F7YXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

688269:THETH RS08430
gene id: 688269:THETH_RS08430
uniprot id: F7YVQ8
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

688269:THETH RS02185
gene id: 688269:THETH_RS02185
uniprot id: F7YW40
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

688269:THETH RS02945
gene id: 688269:THETH_RS02945
uniprot id: F7YXM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

688269:THETH RS01625
gene id: 688269:THETH_RS01625
uniprot id: F7YVC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

688269:THETH RS07050
gene id: 688269:THETH_RS07050
uniprot id: F7YUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS03280
gene id: 688269:THETH_RS03280
uniprot id: F7YX31
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

688269:THETH RS09475
gene id: 688269:THETH_RS09475
uniprot id: F7YWE3
names: Similarity
messages: Belongs to the pyruvate kinase family.

688269:THETH RS04370
gene id: 688269:THETH_RS04370
uniprot id: F7YYC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

688269:THETH RS09970
gene id: 688269:THETH_RS09970
uniprot id: F7YWM4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

688269:THETH RS04120
gene id: 688269:THETH_RS04120
uniprot id: F7YY76
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

688269:THETH RS00995
gene id: 688269:THETH_RS00995
uniprot id: F7YV17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

688269:THETH RS01980
gene id: 688269:THETH_RS01980
uniprot id: F7YW03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS05465
gene id: 688269:THETH_RS05465
uniprot id: F7YYW4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS03835
gene id: 688269:THETH_RS03835
uniprot id: F7YY35
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

688269:THETH RS09755
gene id: 688269:THETH_RS09755
uniprot id: F7YWJ0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

688269:THETH RS03075
gene id: 688269:THETH_RS03075
uniprot id: F7YXQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

688269:THETH RS09745
gene id: 688269:THETH_RS09745
uniprot id: F7YWI8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

688269:THETH RS03430
gene id: 688269:THETH_RS03430
uniprot id: F7YXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

688269:THETH RS06475
gene id: 688269:THETH_RS06475
uniprot id: F7YUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

688269:THETH RS06240
gene id: 688269:THETH_RS06240
uniprot id: F7YUA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Interacts with FtsZ.

688269:THETH RS08550
gene id: 688269:THETH_RS08550
uniprot id: F7YVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS02745
gene id: 688269:THETH_RS02745
uniprot id: F7YXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS01830
gene id: 688269:THETH_RS01830
uniprot id: F7YVF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

688269:THETH RS07700
gene id: 688269:THETH_RS07700
uniprot id: F7YTZ4
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS08105
gene id: 688269:THETH_RS08105
uniprot id: F7YVK3
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS06660
gene id: 688269:THETH_RS06660
uniprot id: F7YTT5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

688269:THETH RS02335
gene id: 688269:THETH_RS02335
uniprot id: F7YWW4
names: Similarity
messages: Belongs to the GARS family.

688269:THETH RS07415
gene id: 688269:THETH_RS07415
uniprot id: F7YUV9
names: Similarity
messages: Belongs to the carbamate kinase family.

688269:THETH RS00160
gene id: 688269:THETH_RS00160
uniprot id: F7YU41
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

688269:THETH RS09490
gene id: 688269:THETH_RS09490
uniprot id: F7YWE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

688269:THETH RS04675
gene id: 688269:THETH_RS04675
uniprot id: F7YYH9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

688269:THETH RS06285
gene id: 688269:THETH_RS06285
uniprot id: F7YUB5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

688269:THETH RS03905
gene id: 688269:THETH_RS03905
uniprot id: F7YY46
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

688269:THETH RS09915
gene id: 688269:THETH_RS09915
uniprot id: F7YWL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

688269:THETH RS04000
gene id: 688269:THETH_RS04000
uniprot id: F7YY59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

688269:THETH RS05780
gene id: 688269:THETH_RS05780
uniprot id: F7YX82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

688269:THETH RS08120
gene id: 688269:THETH_RS08120
uniprot id: F7YVK5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

688269:THETH RS09205
gene id: 688269:THETH_RS09205
uniprot id: F7YWA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

688269:THETH RS08355
gene id: 688269:THETH_RS08355
uniprot id: F7YVP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

688269:THETH RS02775
gene id: 688269:THETH_RS02775
uniprot id: F7YXJ9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

688269:THETH RS06795
gene id: 688269:THETH_RS06795
uniprot id: F7YXA3
names: Similarity
messages: Belongs to the RutC family.

688269:THETH RS06465
gene id: 688269:THETH_RS06465
uniprot id: F7YX97
names: Similarity
messages: Belongs to the DprA/Smf family.

688269:THETH RS03205
gene id: 688269:THETH_RS03205
uniprot id: F7YXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

688269:THETH RS03935
gene id: 688269:THETH_RS03935
uniprot id: F7YY50
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

688269:THETH RS04185
gene id: 688269:THETH_RS04185
uniprot id: F7YY89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

688269:THETH RS00680
gene id: 688269:THETH_RS00680
uniprot id: F7YUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

688269:THETH RS05750
gene id: 688269:THETH_RS05750
uniprot id: F7YTJ2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

688269:THETH RS01730
gene id: 688269:THETH_RS01730
uniprot id: F7YVE0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

688269:THETH RS09715
gene id: 688269:THETH_RS09715
uniprot id: F7YWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

688269:THETH RS06480
gene id: 688269:THETH_RS06480
uniprot id: F7YX98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

688269:THETH RS02565
gene id: 688269:THETH_RS02565
uniprot id: F7YX04
names: Similarity
messages: Belongs to the bacterial secretin family.

688269:THETH RS08990
gene id: 688269:THETH_RS08990
uniprot id: F7YW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS07290
gene id: 688269:THETH_RS07290
uniprot id: F7YUL9
names: Subcellular Location Annotation
messages: Cytoplasm

688269:THETH RS06645
gene id: 688269:THETH_RS06645
uniprot id: F7YTT2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

688269:THETH RS00055
gene id: 688269:THETH_RS00055
uniprot id: F7YTD9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

688269:THETH RS02935
gene id: 688269:THETH_RS02935
uniprot id: F7YXM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

688269:THETH RS07720
gene id: 688269:THETH_RS07720
uniprot id: F7YTZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

688269:THETH RS06095
gene id: 688269:THETH_RS06095
uniprot id: F7YTQ0
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02315
gene id: 688269:THETH_RS02315
uniprot id: F7YWW0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

688269:THETH RS00295
gene id: 688269:THETH_RS00295
uniprot id: F7YU67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

688269:THETH RS00630
gene id: 688269:THETH_RS00630
uniprot id: F7YUP4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

688269:THETH RS01475
gene id: 688269:THETH_RS01475
uniprot id: F7YWU3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

688269:THETH RS10040
gene id: 688269:THETH_RS10040
uniprot id: F7YWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS04245
gene id: 688269:THETH_RS04245
uniprot id: F7YYA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

688269:THETH RS08900
gene id: 688269:THETH_RS08900
uniprot id: F7YVY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

688269:THETH RS03690
gene id: 688269:THETH_RS03690
uniprot id: F7YY08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

688269:THETH RS03710
gene id: 688269:THETH_RS03710
uniprot id: F7YY10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

688269:THETH RS09710
gene id: 688269:THETH_RS09710
uniprot id: F7YWI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

688269:THETH RS06770
gene id: 688269:THETH_RS06770
uniprot id: F7YTV0
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS05315
gene id: 688269:THETH_RS05315
uniprot id: F7YYU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

688269:THETH RS04285
gene id: 688269:THETH_RS04285
uniprot id: F7YYA9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

688269:THETH RS04135
gene id: 688269:THETH_RS04135
uniprot id: F7YY79
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

688269:THETH RS05335
gene id: 688269:THETH_RS05335
uniprot id: F7YYU3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

688269:THETH RS01260
gene id: 688269:THETH_RS01260
uniprot id: F7YV52
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

688269:THETH RS04140
gene id: 688269:THETH_RS04140
uniprot id: F7YY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

688269:THETH RS02700
gene id: 688269:THETH_RS02700
uniprot id: F7YXI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

688269:THETH RS08440
gene id: 688269:THETH_RS08440
uniprot id: F7YVQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS09825
gene id: 688269:THETH_RS09825
uniprot id: F7YWK2
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS07830
gene id: 688269:THETH_RS07830
uniprot id: F7YU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS04130
gene id: 688269:THETH_RS04130
uniprot id: F7YY78
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

688269:THETH RS00835
gene id: 688269:THETH_RS00835
uniprot id: F7YUT0
names: Similarity
messages: Belongs to the HypE family.

688269:THETH RS07595
gene id: 688269:THETH_RS07595
uniprot id: F7YXC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS05120
gene id: 688269:THETH_RS05120
uniprot id: F7YX70
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

688269:THETH RS08950
gene id: 688269:THETH_RS08950
uniprot id: F7YVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

688269:THETH RS01630
gene id: 688269:THETH_RS01630
uniprot id: F7YVC1
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

688269:THETH RS01715
gene id: 688269:THETH_RS01715
uniprot id: F7YVD7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

688269:THETH RS02370
gene id: 688269:THETH_RS02370
uniprot id: F7YWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS03495
gene id: 688269:THETH_RS03495
uniprot id: F7YXX7
names: Similarity
messages: Belongs to the CinA family.

688269:THETH RS03705
gene id: 688269:THETH_RS03705
uniprot id: F7YX44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

688269:THETH RS04800
gene id: 688269:THETH_RS04800
uniprot id: F7YYK0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

688269:THETH RS08150
gene id: 688269:THETH_RS08150
uniprot id: F7YVL0
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS00690
gene id: 688269:THETH_RS00690
uniprot id: F7YUQ6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

688269:THETH RS09885
gene id: 688269:THETH_RS09885
uniprot id: F7YWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

688269:THETH RS01080
gene id: 688269:THETH_RS01080
uniprot id: F7YWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

688269:THETH RS08730
gene id: 688269:THETH_RS08730
uniprot id: F7YVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

688269:THETH RS04295
gene id: 688269:THETH_RS04295
uniprot id: F7YYB1
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

688269:THETH RS01990
gene id: 688269:THETH_RS01990
uniprot id: F7YW05
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

688269:THETH RS03640
gene id: 688269:THETH_RS03640
uniprot id: F7YY01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

688269:THETH RS08815
gene id: 688269:THETH_RS08815
uniprot id: F7YVX4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

688269:THETH RS02635
gene id: 688269:THETH_RS02635
uniprot id: F7YX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

688269:THETH RS07455
gene id: 688269:THETH_RS07455
uniprot id: F7YUW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

688269:THETH RS03630
gene id: 688269:THETH_RS03630
uniprot id: F7YXZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

688269:THETH RS07315
gene id: 688269:THETH_RS07315
uniprot id: F7YUT9
names: Subcellular Location Annotation
messages: Cytoplasm

688269:THETH RS04850
gene id: 688269:THETH_RS04850
uniprot id: F7YYK8
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS07730
gene id: 688269:THETH_RS07730
uniprot id: F7YU00
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS10050
gene id: 688269:THETH_RS10050
uniprot id: F7YWN7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

688269:THETH RS06205
gene id: 688269:THETH_RS06205
uniprot id: F7YTR7
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS05395
gene id: 688269:THETH_RS05395
uniprot id: F7YYV1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

688269:THETH RS01270
gene id: 688269:THETH_RS01270
uniprot id: F7YV54
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS05455
gene id: 688269:THETH_RS05455
uniprot id: F7YYW2
names: Similarity
messages: Belongs to the sigma-54 factor family.

688269:THETH RS01380
gene id: 688269:THETH_RS01380
uniprot id: F7YV79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

688269:THETH RS08685
gene id: 688269:THETH_RS08685
uniprot id: F7YVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

688269:THETH RS00910
gene id: 688269:THETH_RS00910
uniprot id: F7YV00
names: Similarity
messages: Belongs to the LacAB/RpiB family.

688269:THETH RS05190
gene id: 688269:THETH_RS05190
uniprot id: F7YYR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

688269:THETH RS06040
gene id: 688269:THETH_RS06040
uniprot id: F7YTP4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

688269:THETH RS00970
gene id: 688269:THETH_RS00970
uniprot id: F7YV12
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

688269:THETH RS02410
gene id: 688269:THETH_RS02410
uniprot id: F7YWX8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

688269:THETH RS07150
gene id: 688269:THETH_RS07150
uniprot id: F7YUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS04510
gene id: 688269:THETH_RS04510
uniprot id: F7YYE8
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS07650
gene id: 688269:THETH_RS07650
uniprot id: F7YTY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

688269:THETH RS08485
gene id: 688269:THETH_RS08485
uniprot id: F7YVR7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

688269:THETH RS08630
gene id: 688269:THETH_RS08630
uniprot id: F7YVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

688269:THETH RS03285
gene id: 688269:THETH_RS03285
uniprot id: F7YXU1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

688269:THETH RS02545
gene id: 688269:THETH_RS02545
uniprot id: F7YX20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

688269:THETH RS09900
gene id: 688269:THETH_RS09900
uniprot id: F7YWL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

688269:THETH RS09220
gene id: 688269:THETH_RS09220
uniprot id: F7YXF7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

688269:THETH RS02780
gene id: 688269:THETH_RS02780
uniprot id: F7YXK0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

688269:THETH RS03360
gene id: 688269:THETH_RS03360
uniprot id: F7YXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

688269:THETH RS03655
gene id: 688269:THETH_RS03655
uniprot id: F7YY04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

688269:THETH RS03750
gene id: 688269:THETH_RS03750
uniprot id: F7YY18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

688269:THETH RS01925
gene id: 688269:THETH_RS01925
uniprot id: F7YVH0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

688269:THETH RS00370
gene id: 688269:THETH_RS00370
uniprot id: F7YU82
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

688269:THETH RS04760
gene id: 688269:THETH_RS04760
uniprot id: F7YX65
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS08180
gene id: 688269:THETH_RS08180
uniprot id: F7YXD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS00305
gene id: 688269:THETH_RS00305
uniprot id: F7YU69
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS01405
gene id: 688269:THETH_RS01405
uniprot id: F7YV84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

688269:THETH RS04335
gene id: 688269:THETH_RS04335
uniprot id: F7YYB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

688269:THETH RS05220
gene id: 688269:THETH_RS05220
uniprot id: F7YYS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

688269:THETH RS02495
gene id: 688269:THETH_RS02495
uniprot id: F7YWZ4
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS01145
gene id: 688269:THETH_RS01145
uniprot id: F7YWT6
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS06880
gene id: 688269:THETH_RS06880
uniprot id: F7YTW8
names: Similarity
messages: Belongs to the UPF0173 family.

688269:THETH RS08070
gene id: 688269:THETH_RS08070
uniprot id: F7YVJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS01335
gene id: 688269:THETH_RS01335
uniprot id: F7YV69
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

688269:THETH RS08945
gene id: 688269:THETH_RS08945
uniprot id: F7YVZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

688269:THETH RS05710
gene id: 688269:THETH_RS05710
uniprot id: F7YTI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS06905
gene id: 688269:THETH_RS06905
uniprot id: F7YTX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

688269:THETH RS02805
gene id: 688269:THETH_RS02805
uniprot id: F7YXK5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

688269:THETH RS09335
gene id: 688269:THETH_RS09335
uniprot id: F7YWC0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

688269:THETH RS04950
gene id: 688269:THETH_RS04950
uniprot id: F7YYM9
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS06590
gene id: 688269:THETH_RS06590
uniprot id: F7YTS2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

688269:THETH RS02435
gene id: 688269:THETH_RS02435
uniprot id: F7YWY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS06460
gene id: 688269:THETH_RS06460
uniprot id: F7YUE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

688269:THETH RS06490
gene id: 688269:THETH_RS06490
uniprot id: F7YUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

688269:THETH RS04315
gene id: 688269:THETH_RS04315
uniprot id: F7YYB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

688269:THETH RS02925
gene id: 688269:THETH_RS02925
uniprot id: F7YX27
names: Similarity
messages: Belongs to the ComB family.

688269:THETH RS01250
gene id: 688269:THETH_RS01250
uniprot id: F7YV50
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

688269:THETH RS09050
gene id: 688269:THETH_RS09050
uniprot id: F7YW69
names: Similarity
messages: Belongs to the MotB family.

688269:THETH RS04165
gene id: 688269:THETH_RS04165
uniprot id: F7YY85
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

688269:THETH RS02845
gene id: 688269:THETH_RS02845
uniprot id: F7YXL3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

688269:THETH RS02900
gene id: 688269:THETH_RS02900
uniprot id: F7YXM1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

688269:THETH RS09210
gene id: 688269:THETH_RS09210
uniprot id: F7YWA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

688269:THETH RS09650
gene id: 688269:THETH_RS09650
uniprot id: F7YWH2
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

688269:THETH RS01060
gene id: 688269:THETH_RS01060
uniprot id: F7YWS9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

688269:THETH RS03525
gene id: 688269:THETH_RS03525
uniprot id: F7YXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

688269:THETH RS00615
gene id: 688269:THETH_RS00615
uniprot id: F7YUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

688269:THETH RS07385
gene id: 688269:THETH_RS07385
uniprot id: F7YUV3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

688269:THETH RS00200
gene id: 688269:THETH_RS00200
uniprot id: F7YU49
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

688269:THETH RS09890
gene id: 688269:THETH_RS09890
uniprot id: F7YWL2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

688269:THETH RS07470
gene id: 688269:THETH_RS07470
uniprot id: F7YUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS07725
gene id: 688269:THETH_RS07725
uniprot id: F7YTZ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

688269:THETH RS07795
gene id: 688269:THETH_RS07795
uniprot id: F7YU13
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

688269:THETH RS05665
gene id: 688269:THETH_RS05665
uniprot id: F7YTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS03695
gene id: 688269:THETH_RS03695
uniprot id: F7YX43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

688269:THETH RS05210
gene id: 688269:THETH_RS05210
uniprot id: F7YYS2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

688269:THETH RS01195
gene id: 688269:THETH_RS01195
uniprot id: F7YV42
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS07370
gene id: 688269:THETH_RS07370
uniprot id: F7YUV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

688269:THETH RS04420
gene id: 688269:THETH_RS04420
uniprot id: F7YYD2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

688269:THETH RS03680
gene id: 688269:THETH_RS03680
uniprot id: F7YY07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

688269:THETH RS03065
gene id: 688269:THETH_RS03065
uniprot id: F7YXQ1
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

688269:THETH RS07565
gene id: 688269:THETH_RS07565
uniprot id: F7YUY4
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS02765
gene id: 688269:THETH_RS02765
uniprot id: F7YXJ7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

688269:THETH RS07840
gene id: 688269:THETH_RS07840
uniprot id: F7YU21
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

688269:THETH RS04110
gene id: 688269:THETH_RS04110
uniprot id: F7YY74
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS05205
gene id: 688269:THETH_RS05205
uniprot id: F7YYS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

688269:THETH RS00645
gene id: 688269:THETH_RS00645
uniprot id: F7YUP7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

688269:THETH RS05200
gene id: 688269:THETH_RS05200
uniprot id: F7YYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

688269:THETH RS09060
gene id: 688269:THETH_RS09060
uniprot id: F7YW71
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

688269:THETH RS06365
gene id: 688269:THETH_RS06365
uniprot id: F7YUD0
names: Similarity
messages: Belongs to the CutA family.

688269:THETH RS05890
gene id: 688269:THETH_RS05890
uniprot id: F7YTL1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

688269:THETH RS09520
gene id: 688269:THETH_RS09520
uniprot id: F7YWF2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Short' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

688269:THETH RS06195
gene id: 688269:THETH_RS06195
uniprot id: F7YX95
names: Similarity
messages: Belongs to the BMP lipoprotein family.

688269:THETH RS09155
gene id: 688269:THETH_RS09155
uniprot id: F7YW90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

688269:THETH RS02940
gene id: 688269:THETH_RS02940
uniprot id: F7YXM8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

688269:THETH RS02310
gene id: 688269:THETH_RS02310
uniprot id: F7YWV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

688269:THETH RS06485
gene id: 688269:THETH_RS06485
uniprot id: F7YUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

688269:THETH RS00855
gene id: 688269:THETH_RS00855
uniprot id: F7YUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

688269:THETH RS08890
gene id: 688269:THETH_RS08890
uniprot id: F7YVY3
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS03020
gene id: 688269:THETH_RS03020
uniprot id: F7YXP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

688269:THETH RS00075
gene id: 688269:THETH_RS00075
uniprot id: F7YTE4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

688269:THETH RS10035
gene id: 688269:THETH_RS10035
uniprot id: F7YWN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS05415
gene id: 688269:THETH_RS05415
uniprot id: F7YYV5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

688269:THETH RS04945
gene id: 688269:THETH_RS04945
uniprot id: F7YYM8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

688269:THETH RS08435
gene id: 688269:THETH_RS08435
uniprot id: F7YXE0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

688269:THETH RS03625
gene id: 688269:THETH_RS03625
uniprot id: F7YX38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

688269:THETH RS07300
gene id: 688269:THETH_RS07300
uniprot id: F7YUT6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

688269:THETH RS04445
gene id: 688269:THETH_RS04445
uniprot id: F7YYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

688269:THETH RS02450
gene id: 688269:THETH_RS02450
uniprot id: F7YWY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

688269:THETH RS09665
gene id: 688269:THETH_RS09665
uniprot id: F7YWH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS00930
gene id: 688269:THETH_RS00930
uniprot id: F7YV04
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

688269:THETH RS01035
gene id: 688269:THETH_RS01035
uniprot id: F7YV24
names: Similarity
messages: Belongs to the peptidase S58 family.

688269:THETH RS06925
gene id: 688269:THETH_RS06925
uniprot id: F7YTX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

688269:THETH RS09690
gene id: 688269:THETH_RS09690
uniprot id: F7YWH9
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

688269:THETH RS05310
gene id: 688269:THETH_RS05310
uniprot id: F7YYT9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

688269:THETH RS07350
gene id: 688269:THETH_RS07350
uniprot id: F7YUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

688269:THETH RS03920
gene id: 688269:THETH_RS03920
uniprot id: F7YY48
names: Similarity
messages: Belongs to the UPF0111 family.

688269:THETH RS06090
gene id: 688269:THETH_RS06090
uniprot id: F7YX90
names: Similarity
messages: Belongs to the band 7/mec-2 family.

688269:THETH RS09400
gene id: 688269:THETH_RS09400
uniprot id: F7YWC9
names: Subcellular Location Annotation
messages: Cytoplasm

688269:THETH RS02250
gene id: 688269:THETH_RS02250
uniprot id: F7YW53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

688269:THETH RS00020
gene id: 688269:THETH_RS00020
uniprot id: F7YTD3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

688269:THETH RS06125
gene id: 688269:THETH_RS06125
uniprot id: F7YTQ4
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

688269:THETH RS06670
gene id: 688269:THETH_RS06670
uniprot id: F7YTT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS00750
gene id: 688269:THETH_RS00750
uniprot id: F7YUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

688269:THETH RS07970
gene id: 688269:THETH_RS07970
uniprot id: F7YVH6
names: Similarity
messages: Belongs to the peptidase M24B family.

688269:THETH RS00455
gene id: 688269:THETH_RS00455
uniprot id: F7YU94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

688269:THETH RS09385
gene id: 688269:THETH_RS09385
uniprot id: F7YWC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

688269:THETH RS07770
gene id: 688269:THETH_RS07770
uniprot id: F7YU08
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

688269:THETH RS07905
gene id: 688269:THETH_RS07905
uniprot id: F7YXC8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

688269:THETH RS07800
gene id: 688269:THETH_RS07800
uniprot id: F7YU14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

688269:THETH RS04010
gene id: 688269:THETH_RS04010
uniprot id: F7YY61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

688269:THETH RS06845
gene id: 688269:THETH_RS06845
uniprot id: F7YTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

688269:THETH RS07475
gene id: 688269:THETH_RS07475
uniprot id: F7YUX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

688269:THETH RS02510
gene id: 688269:THETH_RS02510
uniprot id: F7YWZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

688269:THETH RS05980
gene id: 688269:THETH_RS05980
uniprot id: F7YTN0
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

688269:THETH RS10135
gene id: 688269:THETH_RS10135
uniprot id: F7YWQ0
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

688269:THETH RS05660
gene id: 688269:THETH_RS05660
uniprot id: F7YTH8
names: Similarity
messages: Belongs to the FGGY kinase family.

688269:THETH RS05495
gene id: 688269:THETH_RS05495
uniprot id: F7YYW9
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

688269:THETH RS01210
gene id: 688269:THETH_RS01210
uniprot id: F7YWU1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

688269:THETH RS09550
gene id: 688269:THETH_RS09550
uniprot id: F7YWF8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

688269:THETH RS04300
gene id: 688269:THETH_RS04300
uniprot id: F7YYB2
names: Similarity
messages: Belongs to the acylphosphatase family.

688269:THETH RS05425
gene id: 688269:THETH_RS05425
uniprot id: F7YYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

688269:THETH RS05150
gene id: 688269:THETH_RS05150
uniprot id: F7YYR2
names: Similarity
messages: Belongs to the AOR/FOR family.

688269:THETH RS03545
gene id: 688269:THETH_RS03545
uniprot id: F7YXY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

688269:THETH RS04930
gene id: 688269:THETH_RS04930
uniprot id: F7YYM5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

688269:THETH RS04600
gene id: 688269:THETH_RS04600
uniprot id: F7YYG8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

688269:THETH RS00460
gene id: 688269:THETH_RS00460
uniprot id: F7YWR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

688269:THETH RS03195
gene id: 688269:THETH_RS03195
uniprot id: F7YXS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

688269:THETH RS02460
gene id: 688269:THETH_RS02460
uniprot id: F7YWY7
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

688269:THETH RS00960
gene id: 688269:THETH_RS00960
uniprot id: F7YV10
names: Subcellular Location Annotation
messages: Membrane

688269:THETH RS03805
gene id: 688269:THETH_RS03805
uniprot id: F7YY29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

688269:THETH RS00490
gene id: 688269:THETH_RS00490
uniprot id: F7YU99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

688269:THETH RS06150
gene id: 688269:THETH_RS06150
uniprot id: F7YTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

688269:THETH RS09300
gene id: 688269:THETH_RS09300
uniprot id: F7YWB6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

688269:THETH RS04910
gene id: 688269:THETH_RS04910
uniprot id: F7YYM0
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

688269:THETH RS04395
gene id: 688269:THETH_RS04395
uniprot id: F7YYC8
names: Similarity
messages: Belongs to the peptidase U62 family.

688269:THETH RS08590
gene id: 688269:THETH_RS08590
uniprot id: F7YVT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

688269:THETH RS08450
gene id: 688269:THETH_RS08450
uniprot id: F7YVR1
names: Similarity
messages: Belongs to the RecJ family.

688269:THETH RS07880
gene id: 688269:THETH_RS07880
uniprot id: F7YU27
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

688269:THETH RS00450
gene id: 688269:THETH_RS00450
uniprot id: F7YWR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

688269:THETH RS04365
gene id: 688269:THETH_RS04365
uniprot id: F7YYC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

688269:THETH RS03875
gene id: 688269:THETH_RS03875
uniprot id: F7YY42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

688269:THETH RS07710
gene id: 688269:THETH_RS07710
uniprot id: F7YTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

688269:THETH RS03060
gene id: 688269:THETH_RS03060
uniprot id: F7YXQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

688269:THETH RS00420
gene id: 688269:THETH_RS00420
uniprot id: F7YWR5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.