682795:ACIX8 RS14070
gene id: 682795:ACIX8_RS14070
uniprot id: G8NP29
names: Similarity
messages: Belongs to the TPP enzyme family.

682795:ACIX8 RS04550
gene id: 682795:ACIX8_RS04550
uniprot id: G8NUA9
names: Similarity
messages: Belongs to the AHA1 family.

682795:ACIX8 RS18935
gene id: 682795:ACIX8_RS18935
uniprot id: G8P1A3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS00540
gene id: 682795:ACIX8_RS00540
uniprot id: G8NYQ3
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS17120
gene id: 682795:ACIX8_RS17120
uniprot id: G8NWF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

682795:ACIX8 RS15965
gene id: 682795:ACIX8_RS15965
uniprot id: G8NNM6
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

682795:ACIX8 RS17805
gene id: 682795:ACIX8_RS17805
uniprot id: G8NYC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

682795:ACIX8 RS09725
gene id: 682795:ACIX8_RS09725
uniprot id: G8NSU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

682795:ACIX8 RS17600
gene id: 682795:ACIX8_RS17600
uniprot id: G8NXE7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

682795:ACIX8 RS18210
gene id: 682795:ACIX8_RS18210
uniprot id: G8NZE5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS12040
gene id: 682795:ACIX8_RS12040
uniprot id: G8NY62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

682795:ACIX8 RS20275
gene id: 682795:ACIX8_RS20275
uniprot id: G8NQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

682795:ACIX8 RS21170
gene id: 682795:ACIX8_RS21170
uniprot id: G8NSI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

682795:ACIX8 RS03480
gene id: 682795:ACIX8_RS03480
uniprot id: G8NRT7
names: Similarity
messages: Belongs to the aldolase LacD family.

682795:ACIX8 RS20975
gene id: 682795:ACIX8_RS20975
uniprot id: G8NSE7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

682795:ACIX8 RS21760
gene id: 682795:ACIX8_RS21760
uniprot id: G8NU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

682795:ACIX8 RS11705
gene id: 682795:ACIX8_RS11705
uniprot id: G8NX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

682795:ACIX8 RS22795
gene id: 682795:ACIX8_RS22795
uniprot id: G8NWK0
names: Similarity
messages: Belongs to the peptidase U62 family.

682795:ACIX8 RS07915
gene id: 682795:ACIX8_RS07915
uniprot id: G8NNR0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

682795:ACIX8 RS05695
gene id: 682795:ACIX8_RS05695
uniprot id: G8NWW4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

682795:ACIX8 RS01710
gene id: 682795:ACIX8_RS01710
uniprot id: G8P1G3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

682795:ACIX8 RS09545
gene id: 682795:ACIX8_RS09545
uniprot id: G8NS45
names: Similarity
messages: Belongs to the peptidase S33 family.

682795:ACIX8 RS14965
gene id: 682795:ACIX8_RS14965
uniprot id: G8NRG2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

682795:ACIX8 RS08905
gene id: 682795:ACIX8_RS08905
uniprot id: G8NQI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

682795:ACIX8 RS09280
gene id: 682795:ACIX8_RS09280
uniprot id: G8NRC7
names: Similarity
messages: Belongs to the cytochrome P450 family.

682795:ACIX8 RS17915
gene id: 682795:ACIX8_RS17915
uniprot id: G8NYE7
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS21045
gene id: 682795:ACIX8_RS21045
uniprot id: G8NSG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS05145
gene id: 682795:ACIX8_RS05145
uniprot id: G8NV94
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

682795:ACIX8 RS18910
gene id: 682795:ACIX8_RS18910
uniprot id: G8P198
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS07010
gene id: 682795:ACIX8_RS07010
uniprot id: G8P042
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

682795:ACIX8 RS00595
gene id: 682795:ACIX8_RS00595
uniprot id: G8NYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS00055
gene id: 682795:ACIX8_RS00055
uniprot id: G8NWT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS04840
gene id: 682795:ACIX8_RS04840
uniprot id: G8NUG6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

682795:ACIX8 RS05980
gene id: 682795:ACIX8_RS05980
uniprot id: G8NX21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

682795:ACIX8 RS03585
gene id: 682795:ACIX8_RS03585
uniprot id: G8NRW1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

682795:ACIX8 RS05950
gene id: 682795:ACIX8_RS05950
uniprot id: G8NX14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS21360
gene id: 682795:ACIX8_RS21360
uniprot id: G8NT85
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS22015
gene id: 682795:ACIX8_RS22015
uniprot id: G8NU97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

682795:ACIX8 RS13040
gene id: 682795:ACIX8_RS13040
uniprot id: G8P108
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

682795:ACIX8 RS05575
gene id: 682795:ACIX8_RS05575
uniprot id: G8NW49
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02885
gene id: 682795:ACIX8_RS02885
uniprot id: G8NQ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

682795:ACIX8 RS13725
gene id: 682795:ACIX8_RS13725
uniprot id: G8NNW5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

682795:ACIX8 RS13480
gene id: 682795:ACIX8_RS13480
uniprot id: G8P1X0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

682795:ACIX8 RS18480
gene id: 682795:ACIX8_RS18480
uniprot id: G8P0D8
names: Similarity
messages: Belongs to the cytochrome P450 family.

682795:ACIX8 RS17185
gene id: 682795:ACIX8_RS17185
uniprot id: G8NWH1
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS21825
gene id: 682795:ACIX8_RS21825
uniprot id: G8NU58
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

682795:ACIX8 RS11575
gene id: 682795:ACIX8_RS11575
uniprot id: G8NX31
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

682795:ACIX8 RS23395
gene id: 682795:ACIX8_RS23395
uniprot id: G8NXL1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS19060
gene id: 682795:ACIX8_RS19060
uniprot id: G8P1C6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

682795:ACIX8 RS20955
gene id: 682795:ACIX8_RS20955
uniprot id: G8NSE3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS02260
gene id: 682795:ACIX8_RS02260
uniprot id: G8NNM6
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

682795:ACIX8 RS05340
gene id: 682795:ACIX8_RS05340
uniprot id: G8NW04
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

682795:ACIX8 RS13080
gene id: 682795:ACIX8_RS13080
uniprot id: G8P116
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS04590
gene id: 682795:ACIX8_RS04590
uniprot id: G8NUB7
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02165
gene id: 682795:ACIX8_RS02165
uniprot id: G8NNK9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

682795:ACIX8 RS18420
gene id: 682795:ACIX8_RS18420
uniprot id: G8P0C6
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

682795:ACIX8 RS13590
gene id: 682795:ACIX8_RS13590
uniprot id: G8P1Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

682795:ACIX8 RS06125
gene id: 682795:ACIX8_RS06125
uniprot id: G8NXZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

682795:ACIX8 RS14125
gene id: 682795:ACIX8_RS14125
uniprot id: G8NPQ5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS04250
gene id: 682795:ACIX8_RS04250
uniprot id: G8NTH2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

682795:ACIX8 RS14030
gene id: 682795:ACIX8_RS14030
uniprot id: G8NP21
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05890
gene id: 682795:ACIX8_RS05890
uniprot id: G8NX02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

682795:ACIX8 RS22730
gene id: 682795:ACIX8_RS22730
uniprot id: G8NVX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

682795:ACIX8 RS17200
gene id: 682795:ACIX8_RS17200
uniprot id: G8NWH4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

682795:ACIX8 RS05935
gene id: 682795:ACIX8_RS05935
uniprot id: G8NX11
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

682795:ACIX8 RS22745
gene id: 682795:ACIX8_RS22745
uniprot id: G8NVX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

682795:ACIX8 RS15155
gene id: 682795:ACIX8_RS15155
uniprot id: G8NRK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

682795:ACIX8 RS23005
gene id: 682795:ACIX8_RS23005
uniprot id: G8NWP4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

682795:ACIX8 RS15890
gene id: 682795:ACIX8_RS15890
uniprot id: G8NTV5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

682795:ACIX8 RS20050
gene id: 682795:ACIX8_RS20050
uniprot id: G8NQ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS05390
gene id: 682795:ACIX8_RS05390
uniprot id: G8NW14
names: Similarity
messages: Belongs to the GSP E family.

682795:ACIX8 RS03980
gene id: 682795:ACIX8_RS03980
uniprot id: G8NSQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

682795:ACIX8 RS02950
gene id: 682795:ACIX8_RS02950
uniprot id: G8NQ90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

682795:ACIX8 RS14225
gene id: 682795:ACIX8_RS14225
uniprot id: G8NPS6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

682795:ACIX8 RS05910
gene id: 682795:ACIX8_RS05910
uniprot id: G8NX07
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

682795:ACIX8 RS01895
gene id: 682795:ACIX8_RS01895
uniprot id: G8P1K1
names: Similarity
messages: Belongs to the UPF0502 family.

682795:ACIX8 RS20350
gene id: 682795:ACIX8_RS20350
uniprot id: G8NQT7
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS13270
gene id: 682795:ACIX8_RS13270
uniprot id: G8P156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS17970
gene id: 682795:ACIX8_RS17970
uniprot id: G8NYF8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

682795:ACIX8 RS05350
gene id: 682795:ACIX8_RS05350
uniprot id: G8NW06
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

682795:ACIX8 RS18735
gene id: 682795:ACIX8_RS18735
uniprot id: G8P0J1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

682795:ACIX8 RS15885
gene id: 682795:ACIX8_RS15885
uniprot id: G8NTV3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

682795:ACIX8 RS15345
gene id: 682795:ACIX8_RS15345
uniprot id: G8NSA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

682795:ACIX8 RS09805
gene id: 682795:ACIX8_RS09805
uniprot id: G8NSV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

682795:ACIX8 RS24570
gene id: 682795:ACIX8_RS24570
uniprot id: G8NY99
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS06915
gene id: 682795:ACIX8_RS06915
uniprot id: G8P024
names: Similarity
messages: Belongs to the OprB family.

682795:ACIX8 RS12675
gene id: 682795:ACIX8_RS12675
uniprot id: G8P068
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS09420
gene id: 682795:ACIX8_RS09420
uniprot id: G8NS23
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

682795:ACIX8 RS18560
gene id: 682795:ACIX8_RS18560
uniprot id: G8P0F5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS17870
gene id: 682795:ACIX8_RS17870
uniprot id: G8NYD9
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

682795:ACIX8 RS22580
gene id: 682795:ACIX8_RS22580
uniprot id: G8NVU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

682795:ACIX8 RS02870
gene id: 682795:ACIX8_RS02870
uniprot id: G8NQ74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

682795:ACIX8 RS04955
gene id: 682795:ACIX8_RS04955
uniprot id: G8NV55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

682795:ACIX8 RS10705
gene id: 682795:ACIX8_RS10705
uniprot id: G8NUM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS10420
gene id: 682795:ACIX8_RS10420
uniprot id: G8NTU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

682795:ACIX8 RS23810
gene id: 682795:ACIX8_RS23810
uniprot id: G8NYN2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

682795:ACIX8 RS16640
gene id: 682795:ACIX8_RS16640
uniprot id: G8NVJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS03195
gene id: 682795:ACIX8_RS03195
uniprot id: G8NR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

682795:ACIX8 RS15820
gene id: 682795:ACIX8_RS15820
uniprot id: G8NRW7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

682795:ACIX8 RS17065
gene id: 682795:ACIX8_RS17065
uniprot id: G8NWE6
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

682795:ACIX8 RS12990
gene id: 682795:ACIX8_RS12990
uniprot id: G8P0Z8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

682795:ACIX8 RS14080
gene id: 682795:ACIX8_RS14080
uniprot id: G8NP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

682795:ACIX8 RS16785
gene id: 682795:ACIX8_RS16785
uniprot id: G8NVM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

682795:ACIX8 RS06855
gene id: 682795:ACIX8_RS06855
uniprot id: G8P012
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

682795:ACIX8 RS13345
gene id: 682795:ACIX8_RS13345
uniprot id: G8P1U3
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

682795:ACIX8 RS18245
gene id: 682795:ACIX8_RS18245
uniprot id: G8NZF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

682795:ACIX8 RS13860
gene id: 682795:ACIX8_RS13860
uniprot id: G8NNZ2
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS11730
gene id: 682795:ACIX8_RS11730
uniprot id: G8NX62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

682795:ACIX8 RS04910
gene id: 682795:ACIX8_RS04910
uniprot id: G8NV46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

682795:ACIX8 RS02930
gene id: 682795:ACIX8_RS02930
uniprot id: G8NQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

682795:ACIX8 RS14100
gene id: 682795:ACIX8_RS14100
uniprot id: G8NPQ0
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS07940
gene id: 682795:ACIX8_RS07940
uniprot id: G8NNR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS23790
gene id: 682795:ACIX8_RS23790
uniprot id: G8NYM8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

682795:ACIX8 RS10280
gene id: 682795:ACIX8_RS10280
uniprot id: G8NTS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

682795:ACIX8 RS18430
gene id: 682795:ACIX8_RS18430
uniprot id: G8P0C8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

682795:ACIX8 RS02660
gene id: 682795:ACIX8_RS02660
uniprot id: G8NPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

682795:ACIX8 RS11110
gene id: 682795:ACIX8_RS11110
uniprot id: G8NVH1
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

682795:ACIX8 RS16265
gene id: 682795:ACIX8_RS16265
uniprot id: G8NUP8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

682795:ACIX8 RS09885
gene id: 682795:ACIX8_RS09885
uniprot id: G8NSX5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

682795:ACIX8 RS06425
gene id: 682795:ACIX8_RS06425
uniprot id: G8NYZ0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

682795:ACIX8 RS21740
gene id: 682795:ACIX8_RS21740
uniprot id: G8NU40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

682795:ACIX8 RS21590
gene id: 682795:ACIX8_RS21590
uniprot id: G8NTD2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

682795:ACIX8 RS18945
gene id: 682795:ACIX8_RS18945
uniprot id: G8P1A5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

682795:ACIX8 RS19020
gene id: 682795:ACIX8_RS19020
uniprot id: G8P1C0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS15375
gene id: 682795:ACIX8_RS15375
uniprot id: G8NSB2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

682795:ACIX8 RS09865
gene id: 682795:ACIX8_RS09865
uniprot id: G8NSX1
names: Similarity
messages: Belongs to the creatininase superfamily.

682795:ACIX8 RS15685
gene id: 682795:ACIX8_RS15685
uniprot id: G8NT38
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

682795:ACIX8 RS12900
gene id: 682795:ACIX8_RS12900
uniprot id: G8P0B1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

682795:ACIX8 RS15330
gene id: 682795:ACIX8_RS15330
uniprot id: G8NSA3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

682795:ACIX8 RS15065
gene id: 682795:ACIX8_RS15065
uniprot id: G8NRI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

682795:ACIX8 RS07140
gene id: 682795:ACIX8_RS07140
uniprot id: G8P0T7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS20815
gene id: 682795:ACIX8_RS20815
uniprot id: G8NRQ0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

682795:ACIX8 RS09385
gene id: 682795:ACIX8_RS09385
uniprot id: G8NS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS13840
gene id: 682795:ACIX8_RS13840
uniprot id: G8NNY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

682795:ACIX8 RS00825
gene id: 682795:ACIX8_RS00825
uniprot id: G8NYV9
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS07420
gene id: 682795:ACIX8_RS07420
uniprot id: G8P0Z2
names: Similarity
messages: Belongs to the asparagine synthetase family.

682795:ACIX8 RS09285
gene id: 682795:ACIX8_RS09285
uniprot id: G8NRC8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

682795:ACIX8 RS10340
gene id: 682795:ACIX8_RS10340
uniprot id: G8NTT3
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS12890
gene id: 682795:ACIX8_RS12890
uniprot id: G8P0A9
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

682795:ACIX8 RS01705
gene id: 682795:ACIX8_RS01705
uniprot id: G8P1G2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

682795:ACIX8 RS00060
gene id: 682795:ACIX8_RS00060
uniprot id: G8NWT4
names: Cofactor
messages: Binds 2 manganese ions per subunit.

682795:ACIX8 RS05730
gene id: 682795:ACIX8_RS05730
uniprot id: G8NWX1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

682795:ACIX8 RS21025
gene id: 682795:ACIX8_RS21025
uniprot id: G8NSF7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS05640
gene id: 682795:ACIX8_RS05640
uniprot id: G8NWV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

682795:ACIX8 RS23065
gene id: 682795:ACIX8_RS23065
uniprot id: G8NWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

682795:ACIX8 RS17310
gene id: 682795:ACIX8_RS17310
uniprot id: G8NWJ6
names: Similarity
messages: Belongs to the hyi family.

682795:ACIX8 RS02895
gene id: 682795:ACIX8_RS02895
uniprot id: G8NQ79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

682795:ACIX8 RS17985
gene id: 682795:ACIX8_RS17985
uniprot id: G8NYG1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

682795:ACIX8 RS16380
gene id: 682795:ACIX8_RS16380
uniprot id: G8NUR9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

682795:ACIX8 RS24005
gene id: 682795:ACIX8_RS24005
uniprot id: G8NZL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

682795:ACIX8 RS00690
gene id: 682795:ACIX8_RS00690
uniprot id: G8NYT4
names: Similarity
messages: Belongs to the YciI family.

682795:ACIX8 RS19700
gene id: 682795:ACIX8_RS19700
uniprot id: G8NP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

682795:ACIX8 RS10565
gene id: 682795:ACIX8_RS10565
uniprot id: G8NUK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

682795:ACIX8 RS09165
gene id: 682795:ACIX8_RS09165
uniprot id: G8NRA6
names: Similarity
messages: To endonucleases of group I introns of fungi and phage.

682795:ACIX8 RS14655
gene id: 682795:ACIX8_RS14655
uniprot id: G8NQM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

682795:ACIX8 RS23945
gene id: 682795:ACIX8_RS23945
uniprot id: G8NZJ8
names: Similarity
messages: Belongs to the ALAD family.

682795:ACIX8 RS21440
gene id: 682795:ACIX8_RS21440
uniprot id: G8NTA2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

682795:ACIX8 RS15250
gene id: 682795:ACIX8_RS15250
uniprot id: G8NS87
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS21930
gene id: 682795:ACIX8_RS21930
uniprot id: G8NU80
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS02820
gene id: 682795:ACIX8_RS02820
uniprot id: G8NQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

682795:ACIX8 RS16905
gene id: 682795:ACIX8_RS16905
uniprot id: G8NVP5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

682795:ACIX8 RS23105
gene id: 682795:ACIX8_RS23105
uniprot id: G8NWR4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08365
gene id: 682795:ACIX8_RS08365
uniprot id: G8NPL5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS15340
gene id: 682795:ACIX8_RS15340
uniprot id: G8NSA5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

682795:ACIX8 RS10125
gene id: 682795:ACIX8_RS10125
uniprot id: G8NTP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

682795:ACIX8 RS04535
gene id: 682795:ACIX8_RS04535
uniprot id: G8NUA6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS21355
gene id: 682795:ACIX8_RS21355
uniprot id: G8NT84
names: Similarity
messages: Belongs to the UPF0102 family.

682795:ACIX8 RS01300
gene id: 682795:ACIX8_RS01300
uniprot id: G8P0K9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

682795:ACIX8 RS16405
gene id: 682795:ACIX8_RS16405
uniprot id: G8NUS3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS16960
gene id: 682795:ACIX8_RS16960
uniprot id: G8NVQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

682795:ACIX8 RS00800
gene id: 682795:ACIX8_RS00800
uniprot id: G8NYV4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

682795:ACIX8 RS09830
gene id: 682795:ACIX8_RS09830
uniprot id: G8NSW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

682795:ACIX8 RS08675
gene id: 682795:ACIX8_RS08675
uniprot id: G8NQD6
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

682795:ACIX8 RS10615
gene id: 682795:ACIX8_RS10615
uniprot id: G8NUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS05240
gene id: 682795:ACIX8_RS05240
uniprot id: G8NVY3
names: Similarity
messages: Belongs to the Lgt family.

682795:ACIX8 RS16480
gene id: 682795:ACIX8_RS16480
uniprot id: G8NUT9
names: Similarity
messages: Belongs to the TPP enzyme family.

682795:ACIX8 RS18760
gene id: 682795:ACIX8_RS18760
uniprot id: G8P0J6
names: Similarity
messages: Belongs to the peptidase S9C family.

682795:ACIX8 RS09435
gene id: 682795:ACIX8_RS09435
uniprot id: G8NS25
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

682795:ACIX8 RS00285
gene id: 682795:ACIX8_RS00285
uniprot id: G8NXS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

682795:ACIX8 RS19535
gene id: 682795:ACIX8_RS19535
uniprot id: G8NP41
names: Similarity
messages: Belongs to the MreC family.

682795:ACIX8 RS05080
gene id: 682795:ACIX8_RS05080
uniprot id: G8NV80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

682795:ACIX8 RS10415
gene id: 682795:ACIX8_RS10415
uniprot id: G8NTU8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

682795:ACIX8 RS20465
gene id: 682795:ACIX8_RS20465
uniprot id: G8NQV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

682795:ACIX8 RS19970
gene id: 682795:ACIX8_RS19970
uniprot id: G8NPZ2
names: Similarity
messages: Belongs to the bacterial secretin family.

682795:ACIX8 RS22600
gene id: 682795:ACIX8_RS22600
uniprot id: G8NVU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

682795:ACIX8 RS02935
gene id: 682795:ACIX8_RS02935
uniprot id: G8NQ87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

682795:ACIX8 RS11995
gene id: 682795:ACIX8_RS11995
uniprot id: G8NY53
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

682795:ACIX8 RS10350
gene id: 682795:ACIX8_RS10350
uniprot id: G8NTT5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS06235
gene id: 682795:ACIX8_RS06235
uniprot id: G8NY14
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

682795:ACIX8 RS04385
gene id: 682795:ACIX8_RS04385
uniprot id: G8NTK0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

682795:ACIX8 RS11590
gene id: 682795:ACIX8_RS11590
uniprot id: G8NX34
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

682795:ACIX8 RS01920
gene id: 682795:ACIX8_RS01920
uniprot id: G8P1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

682795:ACIX8 RS15995
gene id: 682795:ACIX8_RS15995
uniprot id: G8NTX7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

682795:ACIX8 RS24335
gene id: 682795:ACIX8_RS24335
uniprot id: G8NSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS22410
gene id: 682795:ACIX8_RS22410
uniprot id: G8NV40
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

682795:ACIX8 RS20960
gene id: 682795:ACIX8_RS20960
uniprot id: G8NSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

682795:ACIX8 RS14560
gene id: 682795:ACIX8_RS14560
uniprot id: G8NQL0
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS03920
gene id: 682795:ACIX8_RS03920
uniprot id: G8NSN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

682795:ACIX8 RS12635
gene id: 682795:ACIX8_RS12635
uniprot id: G8P060
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

682795:ACIX8 RS11620
gene id: 682795:ACIX8_RS11620
uniprot id: G8NX40
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS00970
gene id: 682795:ACIX8_RS00970
uniprot id: G8NZS5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

682795:ACIX8 RS17450
gene id: 682795:ACIX8_RS17450
uniprot id: G8NXB7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

682795:ACIX8 RS13785
gene id: 682795:ACIX8_RS13785
uniprot id: G8NNX7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

682795:ACIX8 RS02230
gene id: 682795:ACIX8_RS02230
uniprot id: G8NNM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

682795:ACIX8 RS06905
gene id: 682795:ACIX8_RS06905
uniprot id: G8P022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

682795:ACIX8 RS05005
gene id: 682795:ACIX8_RS05005
uniprot id: G8NV65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

682795:ACIX8 RS21770
gene id: 682795:ACIX8_RS21770
uniprot id: G8NU46
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08045
gene id: 682795:ACIX8_RS08045
uniprot id: G8NNT7
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

682795:ACIX8 RS13390
gene id: 682795:ACIX8_RS13390
uniprot id: G8P1V2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS21060
gene id: 682795:ACIX8_RS21060
uniprot id: G8NSG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

682795:ACIX8 RS03615
gene id: 682795:ACIX8_RS03615
uniprot id: G8NRW7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

682795:ACIX8 RS10510
gene id: 682795:ACIX8_RS10510
uniprot id: G8NUJ0
names: Similarity
messages: Belongs to the ribF family.

682795:ACIX8 RS17345
gene id: 682795:ACIX8_RS17345
uniprot id: G8NX99
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05150
gene id: 682795:ACIX8_RS05150
uniprot id: G8NV95
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

682795:ACIX8 RS06725
gene id: 682795:ACIX8_RS06725
uniprot id: G8NZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

682795:ACIX8 RS03230
gene id: 682795:ACIX8_RS03230
uniprot id: G8NR12
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08245
gene id: 682795:ACIX8_RS08245
uniprot id: G8NPI9
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02280
gene id: 682795:ACIX8_RS02280
uniprot id: G8NNN0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

682795:ACIX8 RS03105
gene id: 682795:ACIX8_RS03105
uniprot id: G8NQY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

682795:ACIX8 RS19630
gene id: 682795:ACIX8_RS19630
uniprot id: G8NP60
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS20160
gene id: 682795:ACIX8_RS20160
uniprot id: G8NQ30
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS22480
gene id: 682795:ACIX8_RS22480
uniprot id: G8NVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

682795:ACIX8 RS15770
gene id: 682795:ACIX8_RS15770
uniprot id: G8NT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

682795:ACIX8 RS06520
gene id: 682795:ACIX8_RS06520
uniprot id: G8NZ09
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS04530
gene id: 682795:ACIX8_RS04530
uniprot id: G8NUA5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS19025
gene id: 682795:ACIX8_RS19025
uniprot id: G8P1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

682795:ACIX8 RS00260
gene id: 682795:ACIX8_RS00260
uniprot id: G8NXR6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

682795:ACIX8 RS01110
gene id: 682795:ACIX8_RS01110
uniprot id: G8NZV2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

682795:ACIX8 RS16935
gene id: 682795:ACIX8_RS16935
uniprot id: G8NVQ1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS23145
gene id: 682795:ACIX8_RS23145
uniprot id: G8NWS1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

682795:ACIX8 RS15440
gene id: 682795:ACIX8_RS15440
uniprot id: G8NSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS18640
gene id: 682795:ACIX8_RS18640
uniprot id: G8P0H2
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05975
gene id: 682795:ACIX8_RS05975
uniprot id: G8NX20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

682795:ACIX8 RS01080
gene id: 682795:ACIX8_RS01080
uniprot id: G8NZU6
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS22240
gene id: 682795:ACIX8_RS22240
uniprot id: G8NV05
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05965
gene id: 682795:ACIX8_RS05965
uniprot id: G8NX18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

682795:ACIX8 RS19670
gene id: 682795:ACIX8_RS19670
uniprot id: G8NP68
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS16685
gene id: 682795:ACIX8_RS16685
uniprot id: G8NVJ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

682795:ACIX8 RS02925
gene id: 682795:ACIX8_RS02925
uniprot id: G8NQ85
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

682795:ACIX8 RS06055
gene id: 682795:ACIX8_RS06055
uniprot id: G8NXX7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

682795:ACIX8 RS10865
gene id: 682795:ACIX8_RS10865
uniprot id: G8NVC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

682795:ACIX8 RS01575
gene id: 682795:ACIX8_RS01575
uniprot id: G8P0R7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS06810
gene id: 682795:ACIX8_RS06810
uniprot id: G8P003
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS02830
gene id: 682795:ACIX8_RS02830
uniprot id: G8NQ66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

682795:ACIX8 RS03900
gene id: 682795:ACIX8_RS03900
uniprot id: G8NSN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

682795:ACIX8 RS08465
gene id: 682795:ACIX8_RS08465
uniprot id: G8NPN1
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS22725
gene id: 682795:ACIX8_RS22725
uniprot id: G8NVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

682795:ACIX8 RS22750
gene id: 682795:ACIX8_RS22750
uniprot id: G8NVX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

682795:ACIX8 RS16910
gene id: 682795:ACIX8_RS16910
uniprot id: G8NVP6
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

682795:ACIX8 RS11955
gene id: 682795:ACIX8_RS11955
uniprot id: G8NY45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

682795:ACIX8 RS08660
gene id: 682795:ACIX8_RS08660
uniprot id: G8NQD3
names: Similarity
messages: Belongs to the peptidase M16 family.

682795:ACIX8 RS18425
gene id: 682795:ACIX8_RS18425
uniprot id: G8P0C7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

682795:ACIX8 RS15880
gene id: 682795:ACIX8_RS15880
uniprot id: G8NTV2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

682795:ACIX8 RS09390
gene id: 682795:ACIX8_RS09390
uniprot id: G8NS18
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

682795:ACIX8 RS00425
gene id: 682795:ACIX8_RS00425
uniprot id: G8NXU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

682795:ACIX8 RS06720
gene id: 682795:ACIX8_RS06720
uniprot id: G8NZY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS22175
gene id: 682795:ACIX8_RS22175
uniprot id: G8NUZ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS02620
gene id: 682795:ACIX8_RS02620
uniprot id: G8NPG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS09770
gene id: 682795:ACIX8_RS09770
uniprot id: G8NSV2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS18660
gene id: 682795:ACIX8_RS18660
uniprot id: G8P0H7
names: Similarity
messages: Belongs to the ParB family.

682795:ACIX8 RS21055
gene id: 682795:ACIX8_RS21055
uniprot id: G8NSG3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS06860
gene id: 682795:ACIX8_RS06860
uniprot id: G8P013
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

682795:ACIX8 RS17015
gene id: 682795:ACIX8_RS17015
uniprot id: G8NWD6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

682795:ACIX8 RS03380
gene id: 682795:ACIX8_RS03380
uniprot id: G8NR46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

682795:ACIX8 RS13045
gene id: 682795:ACIX8_RS13045
uniprot id: G8P109
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

682795:ACIX8 RS06440
gene id: 682795:ACIX8_RS06440
uniprot id: G8NYZ3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

682795:ACIX8 RS04735
gene id: 682795:ACIX8_RS04735
uniprot id: G8NUE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

682795:ACIX8 RS16775
gene id: 682795:ACIX8_RS16775
uniprot id: G8NVL7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

682795:ACIX8 RS03695
gene id: 682795:ACIX8_RS03695
uniprot id: G8NRY3
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

682795:ACIX8 RS10650
gene id: 682795:ACIX8_RS10650
uniprot id: G8NUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

682795:ACIX8 RS02965
gene id: 682795:ACIX8_RS02965
uniprot id: G8NQ93
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

682795:ACIX8 RS01500
gene id: 682795:ACIX8_RS01500
uniprot id: G8P0Q2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS07505
gene id: 682795:ACIX8_RS07505
uniprot id: G8P1N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS04870
gene id: 682795:ACIX8_RS04870
uniprot id: G8NUH2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

682795:ACIX8 RS01115
gene id: 682795:ACIX8_RS01115
uniprot id: G8NZV3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

682795:ACIX8 RS22440
gene id: 682795:ACIX8_RS22440
uniprot id: G8NVR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

682795:ACIX8 RS05300
gene id: 682795:ACIX8_RS05300
uniprot id: G8NVZ8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

682795:ACIX8 RS17355
gene id: 682795:ACIX8_RS17355
uniprot id: G8NXA1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

682795:ACIX8 RS03555
gene id: 682795:ACIX8_RS03555
uniprot id: G8NRV5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

682795:ACIX8 RS12000
gene id: 682795:ACIX8_RS12000
uniprot id: G8NY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS23610
gene id: 682795:ACIX8_RS23610
uniprot id: G8NYJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

682795:ACIX8 RS06115
gene id: 682795:ACIX8_RS06115
uniprot id: G8NXY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS05265
gene id: 682795:ACIX8_RS05265
uniprot id: G8NVZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

682795:ACIX8 RS10085
gene id: 682795:ACIX8_RS10085
uniprot id: G8NTN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

682795:ACIX8 RS24010
gene id: 682795:ACIX8_RS24010
uniprot id: G8NZL1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

682795:ACIX8 RS11710
gene id: 682795:ACIX8_RS11710
uniprot id: G8NX58
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

682795:ACIX8 RS06570
gene id: 682795:ACIX8_RS06570
uniprot id: G8NZ18
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

682795:ACIX8 RS01000
gene id: 682795:ACIX8_RS01000
uniprot id: G8NZT1
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS07730
gene id: 682795:ACIX8_RS07730
uniprot id: G8P1S8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

682795:ACIX8 RS04420
gene id: 682795:ACIX8_RS04420
uniprot id: G8NTK7
names: Similarity
messages: Belongs to the glycosyl hydrolase.

682795:ACIX8 RS21670
gene id: 682795:ACIX8_RS21670
uniprot id: G8NTE8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

682795:ACIX8 RS15090
gene id: 682795:ACIX8_RS15090
uniprot id: G8NRI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

682795:ACIX8 RS17470
gene id: 682795:ACIX8_RS17470
uniprot id: G8NXC1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

682795:ACIX8 RS07030
gene id: 682795:ACIX8_RS07030
uniprot id: G8P046
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

682795:ACIX8 RS19325
gene id: 682795:ACIX8_RS19325
uniprot id: G8P252
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

682795:ACIX8 RS17035
gene id: 682795:ACIX8_RS17035
uniprot id: G8NWE0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS01955
gene id: 682795:ACIX8_RS01955
uniprot id: G8P1L3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

682795:ACIX8 RS23540
gene id: 682795:ACIX8_RS23540
uniprot id: G8NYH7
names: Similarity
messages: Belongs to the proline racemase family.

682795:ACIX8 RS16100
gene id: 682795:ACIX8_RS16100
uniprot id: G8NTZ8
names: Similarity
messages: Belongs to the sulfatase family.

682795:ACIX8 RS11760
gene id: 682795:ACIX8_RS11760
uniprot id: G8NX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

682795:ACIX8 RS22040
gene id: 682795:ACIX8_RS22040
uniprot id: G8NUW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

682795:ACIX8 RS02550
gene id: 682795:ACIX8_RS02550
uniprot id: G8NPE8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02915
gene id: 682795:ACIX8_RS02915
uniprot id: G8NQ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

682795:ACIX8 RS18215
gene id: 682795:ACIX8_RS18215
uniprot id: G8NZE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

682795:ACIX8 RS01465
gene id: 682795:ACIX8_RS01465
uniprot id: G8P0P4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

682795:ACIX8 RS06385
gene id: 682795:ACIX8_RS06385
uniprot id: G8NYY2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

682795:ACIX8 RS04275
gene id: 682795:ACIX8_RS04275
uniprot id: G8NTH8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS03795
gene id: 682795:ACIX8_RS03795
uniprot id: G8NSL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

682795:ACIX8 RS10735
gene id: 682795:ACIX8_RS10735
uniprot id: G8NUN4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

682795:ACIX8 RS04650
gene id: 682795:ACIX8_RS04650
uniprot id: G8NUC9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

682795:ACIX8 RS07715
gene id: 682795:ACIX8_RS07715
uniprot id: G8P1S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

682795:ACIX8 RS03175
gene id: 682795:ACIX8_RS03175
uniprot id: G8NR01
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS24230
gene id: 682795:ACIX8_RS24230
uniprot id: G8NZQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

682795:ACIX8 RS14335
gene id: 682795:ACIX8_RS14335
uniprot id: G8NPU9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

682795:ACIX8 RS10425
gene id: 682795:ACIX8_RS10425
uniprot id: G8NTV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

682795:ACIX8 RS04895
gene id: 682795:ACIX8_RS04895
uniprot id: G8NV43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

682795:ACIX8 RS21970
gene id: 682795:ACIX8_RS21970
uniprot id: G8NU88
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS13720
gene id: 682795:ACIX8_RS13720
uniprot id: G8NNW4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS20560
gene id: 682795:ACIX8_RS20560
uniprot id: G8NQX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

682795:ACIX8 RS08950
gene id: 682795:ACIX8_RS08950
uniprot id: G8NR59
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

682795:ACIX8 RS01570
gene id: 682795:ACIX8_RS01570
uniprot id: G8P0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

682795:ACIX8 RS18890
gene id: 682795:ACIX8_RS18890
uniprot id: G8P194
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

682795:ACIX8 RS06060
gene id: 682795:ACIX8_RS06060
uniprot id: G8NXX8
names: Similarity
messages: Belongs to the DprA/Smf family.

682795:ACIX8 RS01250
gene id: 682795:ACIX8_RS01250
uniprot id: G8NZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

682795:ACIX8 RS13620
gene id: 682795:ACIX8_RS13620
uniprot id: G8P1Z8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

682795:ACIX8 RS05900
gene id: 682795:ACIX8_RS05900
uniprot id: G8NX04
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

682795:ACIX8 RS04850
gene id: 682795:ACIX8_RS04850
uniprot id: G8NUG8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

682795:ACIX8 RS03915
gene id: 682795:ACIX8_RS03915
uniprot id: G8NSN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

682795:ACIX8 RS03185
gene id: 682795:ACIX8_RS03185
uniprot id: G8NR03
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS23625
gene id: 682795:ACIX8_RS23625
uniprot id: G8NYJ4
names: Similarity
messages: Belongs to the cytochrome P450 family.

682795:ACIX8 RS12865
gene id: 682795:ACIX8_RS12865
uniprot id: G8P0A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS17875
gene id: 682795:ACIX8_RS17875
uniprot id: G8NYE0
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

682795:ACIX8 RS02865
gene id: 682795:ACIX8_RS02865
uniprot id: G8NQ73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

682795:ACIX8 RS02860
gene id: 682795:ACIX8_RS02860
uniprot id: G8NQ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

682795:ACIX8 RS02540
gene id: 682795:ACIX8_RS02540
uniprot id: G8NPE6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

682795:ACIX8 RS13690
gene id: 682795:ACIX8_RS13690
uniprot id: G8P211
names: Similarity
messages: Belongs to the citrate synthase family.

682795:ACIX8 RS19105
gene id: 682795:ACIX8_RS19105
uniprot id: G8P1D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

682795:ACIX8 RS21420
gene id: 682795:ACIX8_RS21420
uniprot id: G8NT98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

682795:ACIX8 RS09910
gene id: 682795:ACIX8_RS09910
uniprot id: G8NSY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

682795:ACIX8 RS13735
gene id: 682795:ACIX8_RS13735
uniprot id: G8NNW7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

682795:ACIX8 RS18085
gene id: 682795:ACIX8_RS18085
uniprot id: G8NZC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

682795:ACIX8 RS03640
gene id: 682795:ACIX8_RS03640
uniprot id: G8NRX3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

682795:ACIX8 RS17935
gene id: 682795:ACIX8_RS17935
uniprot id: G8NYF1
names: Similarity
messages: Belongs to the TlyA family.

682795:ACIX8 RS01430
gene id: 682795:ACIX8_RS01430
uniprot id: G8P0N6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS05805
gene id: 682795:ACIX8_RS05805
uniprot id: G8NWY5
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

682795:ACIX8 RS03385
gene id: 682795:ACIX8_RS03385
uniprot id: G8NR47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

682795:ACIX8 RS08550
gene id: 682795:ACIX8_RS08550
uniprot id: G8NPP8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08645
gene id: 682795:ACIX8_RS08645
uniprot id: G8NQD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

682795:ACIX8 RS23020
gene id: 682795:ACIX8_RS23020
uniprot id: G8NWP7
names: Similarity
messages: Belongs to the transketolase family.

682795:ACIX8 RS04915
gene id: 682795:ACIX8_RS04915
uniprot id: G8NV47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

682795:ACIX8 RS10440
gene id: 682795:ACIX8_RS10440
uniprot id: G8NUH6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

682795:ACIX8 RS04225
gene id: 682795:ACIX8_RS04225
uniprot id: G8NTG7
names: Similarity
messages: Belongs to the glycosyl hydrolase.

682795:ACIX8 RS13325
gene id: 682795:ACIX8_RS13325
uniprot id: G8P167
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

682795:ACIX8 RS08625
gene id: 682795:ACIX8_RS08625
uniprot id: G8NQC6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

682795:ACIX8 RS22265
gene id: 682795:ACIX8_RS22265
uniprot id: G8NV10
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

682795:ACIX8 RS16010
gene id: 682795:ACIX8_RS16010
uniprot id: G8NTY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

682795:ACIX8 RS00990
gene id: 682795:ACIX8_RS00990
uniprot id: G8NZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS22640
gene id: 682795:ACIX8_RS22640
uniprot id: G8NVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

682795:ACIX8 RS07110
gene id: 682795:ACIX8_RS07110
uniprot id: G8P0T1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

682795:ACIX8 RS03345
gene id: 682795:ACIX8_RS03345
uniprot id: G8NR39
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS10245
gene id: 682795:ACIX8_RS10245
uniprot id: G8NTR6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

682795:ACIX8 RS00080
gene id: 682795:ACIX8_RS00080
uniprot id: G8NWT8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

682795:ACIX8 RS02035
gene id: 682795:ACIX8_RS02035
uniprot id: G8NNI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

682795:ACIX8 RS02635
gene id: 682795:ACIX8_RS02635
uniprot id: G8NPG3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

682795:ACIX8 RS02755
gene id: 682795:ACIX8_RS02755
uniprot id: G8NQ51
names: Similarity
messages: Belongs to the Dps family.

682795:ACIX8 RS10065
gene id: 682795:ACIX8_RS10065
uniprot id: G8NTN0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

682795:ACIX8 RS22215
gene id: 682795:ACIX8_RS22215
uniprot id: G8NV00
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05045
gene id: 682795:ACIX8_RS05045
uniprot id: G8NV73
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

682795:ACIX8 RS06490
gene id: 682795:ACIX8_RS06490
uniprot id: G8NZ03
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS15070
gene id: 682795:ACIX8_RS15070
uniprot id: G8NRI4
names: Similarity
messages: Belongs to the UPF0175 family.

682795:ACIX8 RS07015
gene id: 682795:ACIX8_RS07015
uniprot id: G8P043
names: Similarity
messages: Belongs to the UPF0175 family.

682795:ACIX8 RS02735
gene id: 682795:ACIX8_RS02735
uniprot id: G8NQ47
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS16590
gene id: 682795:ACIX8_RS16590
uniprot id: G8NUW1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS03110
gene id: 682795:ACIX8_RS03110
uniprot id: G8NQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

682795:ACIX8 RS06840
gene id: 682795:ACIX8_RS06840
uniprot id: G8P009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

682795:ACIX8 RS01275
gene id: 682795:ACIX8_RS01275
uniprot id: G8P0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

682795:ACIX8 RS10130
gene id: 682795:ACIX8_RS10130
uniprot id: G8NTP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

682795:ACIX8 RS05565
gene id: 682795:ACIX8_RS05565
uniprot id: G8NW47
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

682795:ACIX8 RS01630
gene id: 682795:ACIX8_RS01630
uniprot id: G8P1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

682795:ACIX8 RS21845
gene id: 682795:ACIX8_RS21845
uniprot id: G8NU62
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS07685
gene id: 682795:ACIX8_RS07685
uniprot id: G8P1R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

682795:ACIX8 RS06780
gene id: 682795:ACIX8_RS06780
uniprot id: G8NZZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

682795:ACIX8 RS14375
gene id: 682795:ACIX8_RS14375
uniprot id: G8NPV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS19965
gene id: 682795:ACIX8_RS19965
uniprot id: G8NPZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

682795:ACIX8 RS24870
gene id: 682795:ACIX8_RS24870
uniprot id: G8NQS4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

682795:ACIX8 RS06185
gene id: 682795:ACIX8_RS06185
uniprot id: G8NY02
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS12945
gene id: 682795:ACIX8_RS12945
uniprot id: G8P0B9
names: Similarity
messages: Belongs to the RecJ family.

682795:ACIX8 RS19125
gene id: 682795:ACIX8_RS19125
uniprot id: G8P1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

682795:ACIX8 RS22035
gene id: 682795:ACIX8_RS22035
uniprot id: G8NUA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

682795:ACIX8 RS16510
gene id: 682795:ACIX8_RS16510
uniprot id: G8NUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

682795:ACIX8 RS13825
gene id: 682795:ACIX8_RS13825
uniprot id: G8NNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

682795:ACIX8 RS13570
gene id: 682795:ACIX8_RS13570
uniprot id: G8P1Y8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08205
gene id: 682795:ACIX8_RS08205
uniprot id: G8NPI1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

682795:ACIX8 RS02055
gene id: 682795:ACIX8_RS02055
uniprot id: G8NNI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS03255
gene id: 682795:ACIX8_RS03255
uniprot id: G8NR18
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

682795:ACIX8 RS00365
gene id: 682795:ACIX8_RS00365
uniprot id: G8NXT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

682795:ACIX8 RS16570
gene id: 682795:ACIX8_RS16570
uniprot id: G8NUV7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

682795:ACIX8 RS21680
gene id: 682795:ACIX8_RS21680
uniprot id: G8NTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

682795:ACIX8 RS22045
gene id: 682795:ACIX8_RS22045
uniprot id: G8NUW9
names: Similarity
messages: Belongs to the TrpF family.

682795:ACIX8 RS10725
gene id: 682795:ACIX8_RS10725
uniprot id: G8NUN2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

682795:ACIX8 RS00155
gene id: 682795:ACIX8_RS00155
uniprot id: G8NXP5
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

682795:ACIX8 RS23965
gene id: 682795:ACIX8_RS23965
uniprot id: G8NZK2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

682795:ACIX8 RS11430
gene id: 682795:ACIX8_RS11430
uniprot id: G8NWA5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS15015
gene id: 682795:ACIX8_RS15015
uniprot id: G8NRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YtcA family.
messages: Membrane

682795:ACIX8 RS23775
gene id: 682795:ACIX8_RS23775
uniprot id: G8NYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

682795:ACIX8 RS06360
gene id: 682795:ACIX8_RS06360
uniprot id: G8NYX6
names: Similarity
messages: Belongs to the glutamine synthetase family.

682795:ACIX8 RS01185
gene id: 682795:ACIX8_RS01185
uniprot id: G8NZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YtcA family.
messages: Membrane

682795:ACIX8 RS10545
gene id: 682795:ACIX8_RS10545
uniprot id: G8NUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

682795:ACIX8 RS00820
gene id: 682795:ACIX8_RS00820
uniprot id: G8NYV8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS06230
gene id: 682795:ACIX8_RS06230
uniprot id: G8NY13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS18115
gene id: 682795:ACIX8_RS18115
uniprot id: G8NZC6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

682795:ACIX8 RS02390
gene id: 682795:ACIX8_RS02390
uniprot id: G8NPB7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

682795:ACIX8 RS11795
gene id: 682795:ACIX8_RS11795
uniprot id: G8NX74
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

682795:ACIX8 RS06465
gene id: 682795:ACIX8_RS06465
uniprot id: G8NYZ8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS09440
gene id: 682795:ACIX8_RS09440
uniprot id: G8NS26
names: Similarity
messages: Belongs to the barstar family.

682795:ACIX8 RS09765
gene id: 682795:ACIX8_RS09765
uniprot id: G8NSV1
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

682795:ACIX8 RS17975
gene id: 682795:ACIX8_RS17975
uniprot id: G8NYF9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS19635
gene id: 682795:ACIX8_RS19635
uniprot id: G8NP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

682795:ACIX8 RS07620
gene id: 682795:ACIX8_RS07620
uniprot id: G8P1Q6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS11365
gene id: 682795:ACIX8_RS11365
uniprot id: G8NW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

682795:ACIX8 RS18780
gene id: 682795:ACIX8_RS18780
uniprot id: G8P170
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

682795:ACIX8 RS02910
gene id: 682795:ACIX8_RS02910
uniprot id: G8NQ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

682795:ACIX8 RS21015
gene id: 682795:ACIX8_RS21015
uniprot id: G8NSF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS03065
gene id: 682795:ACIX8_RS03065
uniprot id: G8NQA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

682795:ACIX8 RS22820
gene id: 682795:ACIX8_RS22820
uniprot id: G8NWK5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS09755
gene id: 682795:ACIX8_RS09755
uniprot id: G8NSU9
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

682795:ACIX8 RS10960
gene id: 682795:ACIX8_RS10960
uniprot id: G8NVE1
names: Similarity
messages: Belongs to the UPF0047 family.

682795:ACIX8 RS12025
gene id: 682795:ACIX8_RS12025
uniprot id: G8NY59
names: Similarity
messages: Belongs to the cytochrome P450 family.

682795:ACIX8 RS23355
gene id: 682795:ACIX8_RS23355
uniprot id: G8NXK4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

682795:ACIX8 RS00405
gene id: 682795:ACIX8_RS00405
uniprot id: G8NXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS00730
gene id: 682795:ACIX8_RS00730
uniprot id: G8NYU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

682795:ACIX8 RS02745
gene id: 682795:ACIX8_RS02745
uniprot id: G8NQ49
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

682795:ACIX8 RS17030
gene id: 682795:ACIX8_RS17030
uniprot id: G8NWD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS08260
gene id: 682795:ACIX8_RS08260
uniprot id: G8NPJ2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

682795:ACIX8 RS18465
gene id: 682795:ACIX8_RS18465
uniprot id: G8P0D5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS11990
gene id: 682795:ACIX8_RS11990
uniprot id: G8NY52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

682795:ACIX8 RS08640
gene id: 682795:ACIX8_RS08640
uniprot id: G8NQC9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

682795:ACIX8 RS02750
gene id: 682795:ACIX8_RS02750
uniprot id: G8NQ50
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

682795:ACIX8 RS08860
gene id: 682795:ACIX8_RS08860
uniprot id: G8NQH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

682795:ACIX8 RS10115
gene id: 682795:ACIX8_RS10115
uniprot id: G8NTP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

682795:ACIX8 RS02575
gene id: 682795:ACIX8_RS02575
uniprot id: G8NPF3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

682795:ACIX8 RS05550
gene id: 682795:ACIX8_RS05550
uniprot id: G8NW44
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS03935
gene id: 682795:ACIX8_RS03935
uniprot id: G8NSP2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

682795:ACIX8 RS05885
gene id: 682795:ACIX8_RS05885
uniprot id: G8NX01
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

682795:ACIX8 RS08160
gene id: 682795:ACIX8_RS08160
uniprot id: G8NNV9
names: Similarity
messages: Belongs to the peptidase S9A family.

682795:ACIX8 RS13265
gene id: 682795:ACIX8_RS13265
uniprot id: G8P155
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

682795:ACIX8 RS17050
gene id: 682795:ACIX8_RS17050
uniprot id: G8NWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS21480
gene id: 682795:ACIX8_RS21480
uniprot id: G8NTB0
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

682795:ACIX8 RS21925
gene id: 682795:ACIX8_RS21925
uniprot id: G8NU78
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

682795:ACIX8 RS19095
gene id: 682795:ACIX8_RS19095
uniprot id: G8P1D4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS01050
gene id: 682795:ACIX8_RS01050
uniprot id: G8NZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

682795:ACIX8 RS16930
gene id: 682795:ACIX8_RS16930
uniprot id: G8NVQ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS03070
gene id: 682795:ACIX8_RS03070
uniprot id: G8NQA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

682795:ACIX8 RS15460
gene id: 682795:ACIX8_RS15460
uniprot id: G8NSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

682795:ACIX8 RS04305
gene id: 682795:ACIX8_RS04305
uniprot id: G8NTI4
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

682795:ACIX8 RS02120
gene id: 682795:ACIX8_RS02120
uniprot id: G8NNK0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

682795:ACIX8 RS22020
gene id: 682795:ACIX8_RS22020
uniprot id: G8NU98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS01305
gene id: 682795:ACIX8_RS01305
uniprot id: G8P0L0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

682795:ACIX8 RS02520
gene id: 682795:ACIX8_RS02520
uniprot id: G8NPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

682795:ACIX8 RS04285
gene id: 682795:ACIX8_RS04285
uniprot id: G8NTI0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS02800
gene id: 682795:ACIX8_RS02800
uniprot id: G8NQ60
names: Similarity
messages: Belongs to the peptidase S9C family.

682795:ACIX8 RS19495
gene id: 682795:ACIX8_RS19495
uniprot id: G8NP34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS21565
gene id: 682795:ACIX8_RS21565
uniprot id: G8NTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

682795:ACIX8 RS20850
gene id: 682795:ACIX8_RS20850
uniprot id: G8NRQ7
names: Similarity
messages: Belongs to the peptidase A31 family.

682795:ACIX8 RS03790
gene id: 682795:ACIX8_RS03790
uniprot id: G8NSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

682795:ACIX8 RS22350
gene id: 682795:ACIX8_RS22350
uniprot id: G8NV28
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS20080
gene id: 682795:ACIX8_RS20080
uniprot id: G8NQ14
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS14435
gene id: 682795:ACIX8_RS14435
uniprot id: G8NPX0
names: Similarity
messages: Belongs to the aldose epimerase family.

682795:ACIX8 RS16000
gene id: 682795:ACIX8_RS16000
uniprot id: G8NTX8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

682795:ACIX8 RS06275
gene id: 682795:ACIX8_RS06275
uniprot id: G8NY22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

682795:ACIX8 RS17435
gene id: 682795:ACIX8_RS17435
uniprot id: G8NXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

682795:ACIX8 RS07565
gene id: 682795:ACIX8_RS07565
uniprot id: G8P1P5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS03425
gene id: 682795:ACIX8_RS03425
uniprot id: G8NR55
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

682795:ACIX8 RS23600
gene id: 682795:ACIX8_RS23600
uniprot id: G8NYI9
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS03815
gene id: 682795:ACIX8_RS03815
uniprot id: G8NSL8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

682795:ACIX8 RS12620
gene id: 682795:ACIX8_RS12620
uniprot id: G8P057
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS09490
gene id: 682795:ACIX8_RS09490
uniprot id: G8NS36
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05130
gene id: 682795:ACIX8_RS05130
uniprot id: G8NV91
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

682795:ACIX8 RS09455
gene id: 682795:ACIX8_RS09455
uniprot id: G8NS29
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

682795:ACIX8 RS15555
gene id: 682795:ACIX8_RS15555
uniprot id: G8NT11
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS17195
gene id: 682795:ACIX8_RS17195
uniprot id: G8NWH3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS17545
gene id: 682795:ACIX8_RS17545
uniprot id: G8NXD6
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS03160
gene id: 682795:ACIX8_RS03160
uniprot id: G8NQZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS12105
gene id: 682795:ACIX8_RS12105
uniprot id: G8NY75
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS00960
gene id: 682795:ACIX8_RS00960
uniprot id: G8NZS3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

682795:ACIX8 RS18360
gene id: 682795:ACIX8_RS18360
uniprot id: G8NZH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS15060
gene id: 682795:ACIX8_RS15060
uniprot id: G8NRI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

682795:ACIX8 RS03805
gene id: 682795:ACIX8_RS03805
uniprot id: G8NSL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

682795:ACIX8 RS01160
gene id: 682795:ACIX8_RS01160
uniprot id: G8NZW2
names: Similarity
messages: Belongs to the darcynin family.

682795:ACIX8 RS19405
gene id: 682795:ACIX8_RS19405
uniprot id: G8P269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

682795:ACIX8 RS10720
gene id: 682795:ACIX8_RS10720
uniprot id: G8NUN1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

682795:ACIX8 RS23755
gene id: 682795:ACIX8_RS23755
uniprot id: G8NYM1
names: Similarity
messages: Belongs to the aldose epimerase family.

682795:ACIX8 RS07040
gene id: 682795:ACIX8_RS07040
uniprot id: G8P048
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

682795:ACIX8 RS14000
gene id: 682795:ACIX8_RS14000
uniprot id: G8NP17
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

682795:ACIX8 RS14380
gene id: 682795:ACIX8_RS14380
uniprot id: G8NPV9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

682795:ACIX8 RS14680
gene id: 682795:ACIX8_RS14680
uniprot id: G8NQN3
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS06105
gene id: 682795:ACIX8_RS06105
uniprot id: G8NXY7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

682795:ACIX8 RS19825
gene id: 682795:ACIX8_RS19825
uniprot id: G8NP97
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

682795:ACIX8 RS23190
gene id: 682795:ACIX8_RS23190
uniprot id: G8NXH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS20150
gene id: 682795:ACIX8_RS20150
uniprot id: G8NQ28
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

682795:ACIX8 RS11105
gene id: 682795:ACIX8_RS11105
uniprot id: G8NVH0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

682795:ACIX8 RS17865
gene id: 682795:ACIX8_RS17865
uniprot id: G8NYD8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

682795:ACIX8 RS22885
gene id: 682795:ACIX8_RS22885
uniprot id: G8NWL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS02250
gene id: 682795:ACIX8_RS02250
uniprot id: G8NNM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS10580
gene id: 682795:ACIX8_RS10580
uniprot id: G8NUK4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

682795:ACIX8 RS05685
gene id: 682795:ACIX8_RS05685
uniprot id: G8NWW2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS21635
gene id: 682795:ACIX8_RS21635
uniprot id: G8NTE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

682795:ACIX8 RS01855
gene id: 682795:ACIX8_RS01855
uniprot id: G8P1J3
names: Similarity
messages: Belongs to the Skp family.

682795:ACIX8 RS13300
gene id: 682795:ACIX8_RS13300
uniprot id: G8P162
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

682795:ACIX8 RS11270
gene id: 682795:ACIX8_RS11270
uniprot id: G8NW71
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS02395
gene id: 682795:ACIX8_RS02395
uniprot id: G8NPB8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

682795:ACIX8 RS23490
gene id: 682795:ACIX8_RS23490
uniprot id: G8NXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS00920
gene id: 682795:ACIX8_RS00920
uniprot id: G8NZR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

682795:ACIX8 RS10660
gene id: 682795:ACIX8_RS10660
uniprot id: G8NUM0
names: Similarity
messages: Belongs to the peptidase S66 family.

682795:ACIX8 RS12550
gene id: 682795:ACIX8_RS12550
uniprot id: G8NZA2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS21720
gene id: 682795:ACIX8_RS21720
uniprot id: G8NU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

682795:ACIX8 RS20980
gene id: 682795:ACIX8_RS20980
uniprot id: G8NSE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

682795:ACIX8 RS22850
gene id: 682795:ACIX8_RS22850
uniprot id: G8NWL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS04990
gene id: 682795:ACIX8_RS04990
uniprot id: G8NV62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

682795:ACIX8 RS10145
gene id: 682795:ACIX8_RS10145
uniprot id: G8NTP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

682795:ACIX8 RS24055
gene id: 682795:ACIX8_RS24055
uniprot id: G8NZM0
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08500
gene id: 682795:ACIX8_RS08500
uniprot id: G8NPN8
names: Similarity
messages: Belongs to the peptidase S9C family.

682795:ACIX8 RS20550
gene id: 682795:ACIX8_RS20550
uniprot id: G8NQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

682795:ACIX8 RS22140
gene id: 682795:ACIX8_RS22140
uniprot id: G8NUY7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

682795:ACIX8 RS17605
gene id: 682795:ACIX8_RS17605
uniprot id: G8NXE8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS01360
gene id: 682795:ACIX8_RS01360
uniprot id: G8P0M1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS14420
gene id: 682795:ACIX8_RS14420
uniprot id: G8NPW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

682795:ACIX8 RS01845
gene id: 682795:ACIX8_RS01845
uniprot id: G8P1J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

682795:ACIX8 RS11735
gene id: 682795:ACIX8_RS11735
uniprot id: G8NX63
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS02840
gene id: 682795:ACIX8_RS02840
uniprot id: G8NQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

682795:ACIX8 RS15005
gene id: 682795:ACIX8_RS15005
uniprot id: G8NRH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

682795:ACIX8 RS12470
gene id: 682795:ACIX8_RS12470
uniprot id: G8NZ86
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

682795:ACIX8 RS22300
gene id: 682795:ACIX8_RS22300
uniprot id: G8NV18
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS00390
gene id: 682795:ACIX8_RS00390
uniprot id: G8NXU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

682795:ACIX8 RS06825
gene id: 682795:ACIX8_RS06825
uniprot id: G8P006
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

682795:ACIX8 RS08010
gene id: 682795:ACIX8_RS08010
uniprot id: G8NNT0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS17920
gene id: 682795:ACIX8_RS17920
uniprot id: G8NYE8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02920
gene id: 682795:ACIX8_RS02920
uniprot id: G8NQ84
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

682795:ACIX8 RS19350
gene id: 682795:ACIX8_RS19350
uniprot id: G8P257
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS17830
gene id: 682795:ACIX8_RS17830
uniprot id: G8NYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

682795:ACIX8 RS23515
gene id: 682795:ACIX8_RS23515
uniprot id: G8NXN5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS04050
gene id: 682795:ACIX8_RS04050
uniprot id: G8NSR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS14445
gene id: 682795:ACIX8_RS14445
uniprot id: G8NQI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

682795:ACIX8 RS06145
gene id: 682795:ACIX8_RS06145
uniprot id: G8NXZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS15140
gene id: 682795:ACIX8_RS15140
uniprot id: G8NRJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

682795:ACIX8 RS05115
gene id: 682795:ACIX8_RS05115
uniprot id: G8NV88
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS16940
gene id: 682795:ACIX8_RS16940
uniprot id: G8NVQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS09920
gene id: 682795:ACIX8_RS09920
uniprot id: G8NSY2
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

682795:ACIX8 RS17300
gene id: 682795:ACIX8_RS17300
uniprot id: G8NWJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS07240
gene id: 682795:ACIX8_RS07240
uniprot id: G8P0V7
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

682795:ACIX8 RS16080
gene id: 682795:ACIX8_RS16080
uniprot id: G8NTZ4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

682795:ACIX8 RS02495
gene id: 682795:ACIX8_RS02495
uniprot id: G8NPD7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS12585
gene id: 682795:ACIX8_RS12585
uniprot id: G8NZA8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

682795:ACIX8 RS10135
gene id: 682795:ACIX8_RS10135
uniprot id: G8NTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

682795:ACIX8 RS07670
gene id: 682795:ACIX8_RS07670
uniprot id: G8P1R6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

682795:ACIX8 RS03200
gene id: 682795:ACIX8_RS03200
uniprot id: G8NR06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

682795:ACIX8 RS04045
gene id: 682795:ACIX8_RS04045
uniprot id: G8NSR4
names: Similarity
messages: Belongs to the acylphosphatase family.

682795:ACIX8 RS20925
gene id: 682795:ACIX8_RS20925
uniprot id: G8NRS1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

682795:ACIX8 RS23050
gene id: 682795:ACIX8_RS23050
uniprot id: G8NWQ2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

682795:ACIX8 RS11540
gene id: 682795:ACIX8_RS11540
uniprot id: G8NWC6
names: Similarity
messages: Belongs to the YciI family.

682795:ACIX8 RS12610
gene id: 682795:ACIX8_RS12610
uniprot id: G8P055
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

682795:ACIX8 RS05085
gene id: 682795:ACIX8_RS05085
uniprot id: G8NV81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

682795:ACIX8 RS10395
gene id: 682795:ACIX8_RS10395
uniprot id: G8NTU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

682795:ACIX8 RS01985
gene id: 682795:ACIX8_RS01985
uniprot id: G8NNH3
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

682795:ACIX8 RS00145
gene id: 682795:ACIX8_RS00145
uniprot id: G8NXP3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

682795:ACIX8 RS13025
gene id: 682795:ACIX8_RS13025
uniprot id: G8P105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

682795:ACIX8 RS19790
gene id: 682795:ACIX8_RS19790
uniprot id: G8NP90
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS00360
gene id: 682795:ACIX8_RS00360
uniprot id: G8NXT5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

682795:ACIX8 RS21155
gene id: 682795:ACIX8_RS21155
uniprot id: G8NSI2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

682795:ACIX8 RS18650
gene id: 682795:ACIX8_RS18650
uniprot id: G8P0H4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

682795:ACIX8 RS21805
gene id: 682795:ACIX8_RS21805
uniprot id: G8NU54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

682795:ACIX8 RS06095
gene id: 682795:ACIX8_RS06095
uniprot id: G8NXY5
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

682795:ACIX8 RS07210
gene id: 682795:ACIX8_RS07210
uniprot id: G8P0V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

682795:ACIX8 RS21830
gene id: 682795:ACIX8_RS21830
uniprot id: G8NU59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

682795:ACIX8 RS21200
gene id: 682795:ACIX8_RS21200
uniprot id: G8NSJ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

682795:ACIX8 RS17315
gene id: 682795:ACIX8_RS17315
uniprot id: G8NWJ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

682795:ACIX8 RS08215
gene id: 682795:ACIX8_RS08215
uniprot id: G8NPI3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

682795:ACIX8 RS21755
gene id: 682795:ACIX8_RS21755
uniprot id: G8NU43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

682795:ACIX8 RS02220
gene id: 682795:ACIX8_RS02220
uniprot id: G8NNL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS04415
gene id: 682795:ACIX8_RS04415
uniprot id: G8NTK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Homodimer.
messages: Monomer.
messages: Secreted

682795:ACIX8 RS11635
gene id: 682795:ACIX8_RS11635
uniprot id: G8NX43
names: Function
names: Similarity
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.

682795:ACIX8 RS10435
gene id: 682795:ACIX8_RS10435
uniprot id: G8NUH5
names: Similarity
messages: Belongs to the glutamate synthase family.

682795:ACIX8 RS20500
gene id: 682795:ACIX8_RS20500
uniprot id: G8NQW6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

682795:ACIX8 RS06015
gene id: 682795:ACIX8_RS06015
uniprot id: G8NXW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

682795:ACIX8 RS18720
gene id: 682795:ACIX8_RS18720
uniprot id: G8P0I8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

682795:ACIX8 RS16770
gene id: 682795:ACIX8_RS16770
uniprot id: G8NVL6
names: Similarity
messages: Belongs to the UPF0234 family.

682795:ACIX8 RS23960
gene id: 682795:ACIX8_RS23960
uniprot id: G8NZK1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

682795:ACIX8 RS09795
gene id: 682795:ACIX8_RS09795
uniprot id: G8NSV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

682795:ACIX8 RS11325
gene id: 682795:ACIX8_RS11325
uniprot id: G8NW83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS10550
gene id: 682795:ACIX8_RS10550
uniprot id: G8NUJ8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS10225
gene id: 682795:ACIX8_RS10225
uniprot id: G8NTR2
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

682795:ACIX8 RS07655
gene id: 682795:ACIX8_RS07655
uniprot id: G8P1R3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS04460
gene id: 682795:ACIX8_RS04460
uniprot id: G8NTL5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS06875
gene id: 682795:ACIX8_RS06875
uniprot id: G8P016
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

682795:ACIX8 RS01670
gene id: 682795:ACIX8_RS01670
uniprot id: G8P1F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

682795:ACIX8 RS01555
gene id: 682795:ACIX8_RS01555
uniprot id: G8P0R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

682795:ACIX8 RS04310
gene id: 682795:ACIX8_RS04310
uniprot id: G8NTI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS06135
gene id: 682795:ACIX8_RS06135
uniprot id: G8NXZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS11950
gene id: 682795:ACIX8_RS11950
uniprot id: G8NY44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

682795:ACIX8 RS03100
gene id: 682795:ACIX8_RS03100
uniprot id: G8NQY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

682795:ACIX8 RS13655
gene id: 682795:ACIX8_RS13655
uniprot id: G8P204
names: Similarity
messages: Belongs to the BshC family.

682795:ACIX8 RS00150
gene id: 682795:ACIX8_RS00150
uniprot id: G8NXP4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS10070
gene id: 682795:ACIX8_RS10070
uniprot id: G8NTN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS16395
gene id: 682795:ACIX8_RS16395
uniprot id: G8NUS1
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS11720
gene id: 682795:ACIX8_RS11720
uniprot id: G8NX60
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

682795:ACIX8 RS19190
gene id: 682795:ACIX8_RS19190
uniprot id: G8P225
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

682795:ACIX8 RS02305
gene id: 682795:ACIX8_RS02305
uniprot id: G8NNN5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

682795:ACIX8 RS17330
gene id: 682795:ACIX8_RS17330
uniprot id: G8NX96
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

682795:ACIX8 RS17550
gene id: 682795:ACIX8_RS17550
uniprot id: G8NXD7
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS16545
gene id: 682795:ACIX8_RS16545
uniprot id: G8NUV2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

682795:ACIX8 RS02880
gene id: 682795:ACIX8_RS02880
uniprot id: G8NQ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

682795:ACIX8 RS18805
gene id: 682795:ACIX8_RS18805
uniprot id: G8P175
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

682795:ACIX8 RS21495
gene id: 682795:ACIX8_RS21495
uniprot id: G8NTB3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

682795:ACIX8 RS06140
gene id: 682795:ACIX8_RS06140
uniprot id: G8NXZ4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

682795:ACIX8 RS13290
gene id: 682795:ACIX8_RS13290
uniprot id: G8P160
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS22675
gene id: 682795:ACIX8_RS22675
uniprot id: G8NVW0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

682795:ACIX8 RS23370
gene id: 682795:ACIX8_RS23370
uniprot id: G8NXK6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

682795:ACIX8 RS22805
gene id: 682795:ACIX8_RS22805
uniprot id: G8NWK2
names: Similarity
messages: Belongs to the peptidase U62 family.

682795:ACIX8 RS10185
gene id: 682795:ACIX8_RS10185
uniprot id: G8NTQ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS00235
gene id: 682795:ACIX8_RS00235
uniprot id: G8NXR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

682795:ACIX8 RS03700
gene id: 682795:ACIX8_RS03700
uniprot id: G8NRY4
names: Similarity
messages: Belongs to the PspA/IM30 family.

682795:ACIX8 RS04645
gene id: 682795:ACIX8_RS04645
uniprot id: G8NUC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS08030
gene id: 682795:ACIX8_RS08030
uniprot id: G8NNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

682795:ACIX8 RS02000
gene id: 682795:ACIX8_RS02000
uniprot id: G8NNH6
names: Similarity
messages: Belongs to the LOG family.

682795:ACIX8 RS22540
gene id: 682795:ACIX8_RS22540
uniprot id: G8NVT3
names: Similarity
messages: Belongs to the peptidase M13 family.

682795:ACIX8 RS22995
gene id: 682795:ACIX8_RS22995
uniprot id: G8NWP2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

682795:ACIX8 RS04195
gene id: 682795:ACIX8_RS04195
uniprot id: G8NTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS22000
gene id: 682795:ACIX8_RS22000
uniprot id: G8NU94
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS03415
gene id: 682795:ACIX8_RS03415
uniprot id: G8NR53
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS13960
gene id: 682795:ACIX8_RS13960
uniprot id: G8NP09
names: Similarity
messages: Belongs to the universal stress protein A family.

682795:ACIX8 RS22060
gene id: 682795:ACIX8_RS22060
uniprot id: G8NUX2
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

682795:ACIX8 RS06640
gene id: 682795:ACIX8_RS06640
uniprot id: G8NZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

682795:ACIX8 RS22760
gene id: 682795:ACIX8_RS22760
uniprot id: G8NVX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

682795:ACIX8 RS20875
gene id: 682795:ACIX8_RS20875
uniprot id: G8NRR2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS24025
gene id: 682795:ACIX8_RS24025
uniprot id: G8NZL4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

682795:ACIX8 RS16455
gene id: 682795:ACIX8_RS16455
uniprot id: G8NUT4
names: Similarity
messages: Belongs to the P(II) protein family.

682795:ACIX8 RS09500
gene id: 682795:ACIX8_RS09500
uniprot id: G8NS38
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

682795:ACIX8 RS22235
gene id: 682795:ACIX8_RS22235
uniprot id: G8NV04
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

682795:ACIX8 RS01550
gene id: 682795:ACIX8_RS01550
uniprot id: G8P0R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

682795:ACIX8 RS19090
gene id: 682795:ACIX8_RS19090
uniprot id: G8P1D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

682795:ACIX8 RS19595
gene id: 682795:ACIX8_RS19595
uniprot id: G8NP53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

682795:ACIX8 RS18570
gene id: 682795:ACIX8_RS18570
uniprot id: G8P0F8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS24385
gene id: 682795:ACIX8_RS24385
uniprot id: G8NWX2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

682795:ACIX8 RS22190
gene id: 682795:ACIX8_RS22190
uniprot id: G8NUZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS17080
gene id: 682795:ACIX8_RS17080
uniprot id: G8NWE9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS24070
gene id: 682795:ACIX8_RS24070
uniprot id: G8NZM3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

682795:ACIX8 RS17125
gene id: 682795:ACIX8_RS17125
uniprot id: G8NWF8
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

682795:ACIX8 RS04785
gene id: 682795:ACIX8_RS04785
uniprot id: G8NUF7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS02975
gene id: 682795:ACIX8_RS02975
uniprot id: G8NQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS09260
gene id: 682795:ACIX8_RS09260
uniprot id: G8NRC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

682795:ACIX8 RS18455
gene id: 682795:ACIX8_RS18455
uniprot id: G8P0D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

682795:ACIX8 RS06735
gene id: 682795:ACIX8_RS06735
uniprot id: G8NZY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

682795:ACIX8 RS23135
gene id: 682795:ACIX8_RS23135
uniprot id: G8NWR9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

682795:ACIX8 RS13350
gene id: 682795:ACIX8_RS13350
uniprot id: G8P1U4
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

682795:ACIX8 RS20395
gene id: 682795:ACIX8_RS20395
uniprot id: G8NQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS02790
gene id: 682795:ACIX8_RS02790
uniprot id: G8NQ58
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

682795:ACIX8 RS03290
gene id: 682795:ACIX8_RS03290
uniprot id: G8NR27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS24125
gene id: 682795:ACIX8_RS24125
uniprot id: G8NZN3
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS00375
gene id: 682795:ACIX8_RS00375
uniprot id: G8NXT8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

682795:ACIX8 RS08895
gene id: 682795:ACIX8_RS08895
uniprot id: G8NQH8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS06090
gene id: 682795:ACIX8_RS06090
uniprot id: G8NXY4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS09325
gene id: 682795:ACIX8_RS09325
uniprot id: G8NS06
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

682795:ACIX8 RS08845
gene id: 682795:ACIX8_RS08845
uniprot id: G8NQG8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

682795:ACIX8 RS13750
gene id: 682795:ACIX8_RS13750
uniprot id: G8NNX0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

682795:ACIX8 RS16020
gene id: 682795:ACIX8_RS16020
uniprot id: G8NTY3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS15950
gene id: 682795:ACIX8_RS15950
uniprot id: G8NTW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

682795:ACIX8 RS22315
gene id: 682795:ACIX8_RS22315
uniprot id: G8NV21
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

682795:ACIX8 RS02835
gene id: 682795:ACIX8_RS02835
uniprot id: G8NQ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

682795:ACIX8 RS24195
gene id: 682795:ACIX8_RS24195
uniprot id: G8NZP6
names: Similarity
messages: Belongs to the ParB family.

682795:ACIX8 RS05105
gene id: 682795:ACIX8_RS05105
uniprot id: G8NV86
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

682795:ACIX8 RS05370
gene id: 682795:ACIX8_RS05370
uniprot id: G8NW10
names: Subcellular Location Annotation
messages: Cytoplasm

682795:ACIX8 RS12700
gene id: 682795:ACIX8_RS12700
uniprot id: G8P074
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS17930
gene id: 682795:ACIX8_RS17930
uniprot id: G8NYF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS12655
gene id: 682795:ACIX8_RS12655
uniprot id: G8P064
names: Cofactor
messages: Binds 2 manganese ions per subunit.

682795:ACIX8 RS23675
gene id: 682795:ACIX8_RS23675
uniprot id: G8NYK5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS08310
gene id: 682795:ACIX8_RS08310
uniprot id: G8NPK4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS16450
gene id: 682795:ACIX8_RS16450
uniprot id: G8NUT3
names: Activity Regulation
names: Caution
names: Domain
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

682795:ACIX8 RS06925
gene id: 682795:ACIX8_RS06925
uniprot id: G8P026
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

682795:ACIX8 RS20920
gene id: 682795:ACIX8_RS20920
uniprot id: G8NRS0
names: Similarity
messages: Belongs to the peptidase S49 family.

682795:ACIX8 RS06205
gene id: 682795:ACIX8_RS06205
uniprot id: G8NY07
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08670
gene id: 682795:ACIX8_RS08670
uniprot id: G8NQD5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

682795:ACIX8 RS13360
gene id: 682795:ACIX8_RS13360
uniprot id: G8P1U6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

682795:ACIX8 RS01530
gene id: 682795:ACIX8_RS01530
uniprot id: G8P0Q8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS12560
gene id: 682795:ACIX8_RS12560
uniprot id: G8NZA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

682795:ACIX8 RS05000
gene id: 682795:ACIX8_RS05000
uniprot id: G8NV64
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

682795:ACIX8 RS13440
gene id: 682795:ACIX8_RS13440
uniprot id: G8P1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

682795:ACIX8 RS23010
gene id: 682795:ACIX8_RS23010
uniprot id: G8NWP5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS16950
gene id: 682795:ACIX8_RS16950
uniprot id: G8NVQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

682795:ACIX8 RS02815
gene id: 682795:ACIX8_RS02815
uniprot id: G8NQ63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

682795:ACIX8 RS06665
gene id: 682795:ACIX8_RS06665
uniprot id: G8NZ37
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

682795:ACIX8 RS17980
gene id: 682795:ACIX8_RS17980
uniprot id: G8NYG0
names: Similarity
messages: Belongs to the GARS family.

682795:ACIX8 RS07950
gene id: 682795:ACIX8_RS07950
uniprot id: G8NNR7
names: Similarity
messages: Belongs to the catalase family.

682795:ACIX8 RS21430
gene id: 682795:ACIX8_RS21430
uniprot id: G8NTA0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

682795:ACIX8 RS18885
gene id: 682795:ACIX8_RS18885
uniprot id: G8P193
names: Subcellular Location Annotation
messages: Cytoplasm

682795:ACIX8 RS19215
gene id: 682795:ACIX8_RS19215
uniprot id: G8P230
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS18000
gene id: 682795:ACIX8_RS18000
uniprot id: G8NYG4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS09505
gene id: 682795:ACIX8_RS09505
uniprot id: G8NS39
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

682795:ACIX8 RS18460
gene id: 682795:ACIX8_RS18460
uniprot id: G8P0D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

682795:ACIX8 RS23225
gene id: 682795:ACIX8_RS23225
uniprot id: G8NXH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

682795:ACIX8 RS18240
gene id: 682795:ACIX8_RS18240
uniprot id: G8NZF1
names: Similarity
messages: Belongs to the aspartokinase family.

682795:ACIX8 RS05195
gene id: 682795:ACIX8_RS05195
uniprot id: G8NVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

682795:ACIX8 RS21070
gene id: 682795:ACIX8_RS21070
uniprot id: G8NSG6
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

682795:ACIX8 RS22250
gene id: 682795:ACIX8_RS22250
uniprot id: G8NV07
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS11040
gene id: 682795:ACIX8_RS11040
uniprot id: G8NVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

682795:ACIX8 RS05385
gene id: 682795:ACIX8_RS05385
uniprot id: G8NW13
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

682795:ACIX8 RS26295
gene id: 682795:ACIX8_RS26295
uniprot id: G8NT99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS03025
gene id: 682795:ACIX8_RS03025
uniprot id: G8NQA0
names: Similarity
messages: Belongs to the peptidase S33 family.

682795:ACIX8 RS24460
gene id: 682795:ACIX8_RS24460
uniprot id: G8NPM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

682795:ACIX8 RS20965
gene id: 682795:ACIX8_RS20965
uniprot id: G8NSE5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

682795:ACIX8 RS18250
gene id: 682795:ACIX8_RS18250
uniprot id: G8NZF4
names: Similarity
messages: Belongs to the peptidase M29 family.

682795:ACIX8 RS20575
gene id: 682795:ACIX8_RS20575
uniprot id: G8NQY0
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

682795:ACIX8 RS16835
gene id: 682795:ACIX8_RS16835
uniprot id: G8NVN0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

682795:ACIX8 RS13755
gene id: 682795:ACIX8_RS13755
uniprot id: G8NNX1
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05200
gene id: 682795:ACIX8_RS05200
uniprot id: G8NVA5
names: Subcellular Location Annotation
messages: Cytoplasm

682795:ACIX8 RS17965
gene id: 682795:ACIX8_RS17965
uniprot id: G8NYF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

682795:ACIX8 RS09370
gene id: 682795:ACIX8_RS09370
uniprot id: G8NS14
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

682795:ACIX8 RS11755
gene id: 682795:ACIX8_RS11755
uniprot id: G8NX67
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS05880
gene id: 682795:ACIX8_RS05880
uniprot id: G8NX00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

682795:ACIX8 RS06245
gene id: 682795:ACIX8_RS06245
uniprot id: G8NY16
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS09425
gene id: 682795:ACIX8_RS09425
uniprot id: G8NS24
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

682795:ACIX8 RS16255
gene id: 682795:ACIX8_RS16255
uniprot id: G8NUP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS00935
gene id: 682795:ACIX8_RS00935
uniprot id: G8NZR7
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS21600
gene id: 682795:ACIX8_RS21600
uniprot id: G8NTD4
names: Similarity
messages: Belongs to the DtxR/MntR family.

682795:ACIX8 RS15355
gene id: 682795:ACIX8_RS15355
uniprot id: G8NSA8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS17845
gene id: 682795:ACIX8_RS17845
uniprot id: G8NYD4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02485
gene id: 682795:ACIX8_RS02485
uniprot id: G8NPD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

682795:ACIX8 RS06835
gene id: 682795:ACIX8_RS06835
uniprot id: G8P008
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

682795:ACIX8 RS12475
gene id: 682795:ACIX8_RS12475
uniprot id: G8NZ87
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

682795:ACIX8 RS09800
gene id: 682795:ACIX8_RS09800
uniprot id: G8NSV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

682795:ACIX8 RS08485
gene id: 682795:ACIX8_RS08485
uniprot id: G8NPN5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS19010
gene id: 682795:ACIX8_RS19010
uniprot id: G8P1B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

682795:ACIX8 RS05285
gene id: 682795:ACIX8_RS05285
uniprot id: G8NVZ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

682795:ACIX8 RS22870
gene id: 682795:ACIX8_RS22870
uniprot id: G8NWL4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS21935
gene id: 682795:ACIX8_RS21935
uniprot id: G8NU81
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

682795:ACIX8 RS01715
gene id: 682795:ACIX8_RS01715
uniprot id: G8P1G4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

682795:ACIX8 RS16715
gene id: 682795:ACIX8_RS16715
uniprot id: G8NVK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS08685
gene id: 682795:ACIX8_RS08685
uniprot id: G8NQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

682795:ACIX8 RS07500
gene id: 682795:ACIX8_RS07500
uniprot id: G8P1N1
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS09815
gene id: 682795:ACIX8_RS09815
uniprot id: G8NSW1
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

682795:ACIX8 RS05125
gene id: 682795:ACIX8_RS05125
uniprot id: G8NV90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

682795:ACIX8 RS05810
gene id: 682795:ACIX8_RS05810
uniprot id: G8NWY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

682795:ACIX8 RS16720
gene id: 682795:ACIX8_RS16720
uniprot id: G8NVK6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

682795:ACIX8 RS02465
gene id: 682795:ACIX8_RS02465
uniprot id: G8NPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

682795:ACIX8 RS13050
gene id: 682795:ACIX8_RS13050
uniprot id: G8P110
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

682795:ACIX8 RS18755
gene id: 682795:ACIX8_RS18755
uniprot id: G8P0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

682795:ACIX8 RS21900
gene id: 682795:ACIX8_RS21900
uniprot id: G8NU73
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

682795:ACIX8 RS07605
gene id: 682795:ACIX8_RS07605
uniprot id: G8P1Q3
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05770
gene id: 682795:ACIX8_RS05770
uniprot id: G8NWX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

682795:ACIX8 RS00045
gene id: 682795:ACIX8_RS00045
uniprot id: G8NWT1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS24120
gene id: 682795:ACIX8_RS24120
uniprot id: G8NZN2
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS10835
gene id: 682795:ACIX8_RS10835
uniprot id: G8NVC1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS07430
gene id: 682795:ACIX8_RS07430
uniprot id: G8P0Z4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

682795:ACIX8 RS08885
gene id: 682795:ACIX8_RS08885
uniprot id: G8NQH6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

682795:ACIX8 RS05030
gene id: 682795:ACIX8_RS05030
uniprot id: G8NV70
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

682795:ACIX8 RS06620
gene id: 682795:ACIX8_RS06620
uniprot id: G8NZ28
names: Similarity
messages: Belongs to the Pal lipoprotein family.

682795:ACIX8 RS03985
gene id: 682795:ACIX8_RS03985
uniprot id: G8NSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

682795:ACIX8 RS00940
gene id: 682795:ACIX8_RS00940
uniprot id: G8NZR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

682795:ACIX8 RS04170
gene id: 682795:ACIX8_RS04170
uniprot id: G8NTF6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS15920
gene id: 682795:ACIX8_RS15920
uniprot id: G8NTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

682795:ACIX8 RS19445
gene id: 682795:ACIX8_RS19445
uniprot id: G8P277
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

682795:ACIX8 RS04365
gene id: 682795:ACIX8_RS04365
uniprot id: G8NTJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS15730
gene id: 682795:ACIX8_RS15730
uniprot id: G8NT47
names: Similarity
messages: Belongs to the HsdR family.

682795:ACIX8 RS20295
gene id: 682795:ACIX8_RS20295
uniprot id: G8NQS6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

682795:ACIX8 RS19885
gene id: 682795:ACIX8_RS19885
uniprot id: G8NPX4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS21080
gene id: 682795:ACIX8_RS21080
uniprot id: G8NSG7
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS23470
gene id: 682795:ACIX8_RS23470
uniprot id: G8NXM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

682795:ACIX8 RS03560
gene id: 682795:ACIX8_RS03560
uniprot id: G8NRV6
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

682795:ACIX8 RS18450
gene id: 682795:ACIX8_RS18450
uniprot id: G8P0D2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS02005
gene id: 682795:ACIX8_RS02005
uniprot id: G8NNH7
names: Similarity
messages: Belongs to the RNase T2 family.

682795:ACIX8 RS01280
gene id: 682795:ACIX8_RS01280
uniprot id: G8P0K5
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

682795:ACIX8 RS04810
gene id: 682795:ACIX8_RS04810
uniprot id: G8NUG2
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS19890
gene id: 682795:ACIX8_RS19890
uniprot id: G8NPX5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

682795:ACIX8 RS20945
gene id: 682795:ACIX8_RS20945
uniprot id: G8NRS6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

682795:ACIX8 RS00095
gene id: 682795:ACIX8_RS00095
uniprot id: G8NWU1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

682795:ACIX8 RS13385
gene id: 682795:ACIX8_RS13385
uniprot id: G8P1V1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS21730
gene id: 682795:ACIX8_RS21730
uniprot id: G8NU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

682795:ACIX8 RS16360
gene id: 682795:ACIX8_RS16360
uniprot id: G8NUR4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

682795:ACIX8 RS25865
gene id: 682795:ACIX8_RS25865
uniprot id: G8NZ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS09375
gene id: 682795:ACIX8_RS09375
uniprot id: G8NS15
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

682795:ACIX8 RS17615
gene id: 682795:ACIX8_RS17615
uniprot id: G8NXF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

682795:ACIX8 RS06035
gene id: 682795:ACIX8_RS06035
uniprot id: G8NXX3
names: Similarity
messages: Belongs to the peptidase M13 family.

682795:ACIX8 RS07795
gene id: 682795:ACIX8_RS07795
uniprot id: G8P1U0
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

682795:ACIX8 RS19780
gene id: 682795:ACIX8_RS19780
uniprot id: G8NP88
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS01665
gene id: 682795:ACIX8_RS01665
uniprot id: G8P1F4
names: Similarity
messages: Belongs to the citrate synthase family.

682795:ACIX8 RS04220
gene id: 682795:ACIX8_RS04220
uniprot id: G8NTG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

682795:ACIX8 RS16500
gene id: 682795:ACIX8_RS16500
uniprot id: G8NUU3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS24635
gene id: 682795:ACIX8_RS24635
uniprot id: G8NPT2
names: Similarity
messages: Belongs to the VgrG protein family.

682795:ACIX8 RS14190
gene id: 682795:ACIX8_RS14190
uniprot id: G8NPR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

682795:ACIX8 RS07085
gene id: 682795:ACIX8_RS07085
uniprot id: G8NNM6
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

682795:ACIX8 RS07645
gene id: 682795:ACIX8_RS07645
uniprot id: G8P1R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

682795:ACIX8 RS10075
gene id: 682795:ACIX8_RS10075
uniprot id: G8NTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

682795:ACIX8 RS19070
gene id: 682795:ACIX8_RS19070
uniprot id: G8P1C8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

682795:ACIX8 RS08275
gene id: 682795:ACIX8_RS08275
uniprot id: G8NPJ5
names: Similarity
messages: Belongs to the FPG family.

682795:ACIX8 RS21880
gene id: 682795:ACIX8_RS21880
uniprot id: G8NU69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS04295
gene id: 682795:ACIX8_RS04295
uniprot id: G8NTI2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS02020
gene id: 682795:ACIX8_RS02020
uniprot id: G8NNI1
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS19740
gene id: 682795:ACIX8_RS19740
uniprot id: G8NP81
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02145
gene id: 682795:ACIX8_RS02145
uniprot id: G8NNK5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

682795:ACIX8 RS14675
gene id: 682795:ACIX8_RS14675
uniprot id: G8NQN2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

682795:ACIX8 RS02810
gene id: 682795:ACIX8_RS02810
uniprot id: G8NQ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

682795:ACIX8 RS07105
gene id: 682795:ACIX8_RS07105
uniprot id: G8P0T0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

682795:ACIX8 RS16955
gene id: 682795:ACIX8_RS16955
uniprot id: G8NVQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

682795:ACIX8 RS23335
gene id: 682795:ACIX8_RS23335
uniprot id: G8NXK0
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

682795:ACIX8 RS19565
gene id: 682795:ACIX8_RS19565
uniprot id: G8NP47
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

682795:ACIX8 RS06730
gene id: 682795:ACIX8_RS06730
uniprot id: G8NZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

682795:ACIX8 RS10030
gene id: 682795:ACIX8_RS10030
uniprot id: G8NT03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

682795:ACIX8 RS07635
gene id: 682795:ACIX8_RS07635
uniprot id: G8P1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

682795:ACIX8 RS12050
gene id: 682795:ACIX8_RS12050
uniprot id: G8NY64
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

682795:ACIX8 RS21685
gene id: 682795:ACIX8_RS21685
uniprot id: G8NU29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

682795:ACIX8 RS04270
gene id: 682795:ACIX8_RS04270
uniprot id: G8NTH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

682795:ACIX8 RS15150
gene id: 682795:ACIX8_RS15150
uniprot id: G8NRK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

682795:ACIX8 RS22685
gene id: 682795:ACIX8_RS22685
uniprot id: G8NVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

682795:ACIX8 RS06365
gene id: 682795:ACIX8_RS06365
uniprot id: G8NYX7
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

682795:ACIX8 RS10060
gene id: 682795:ACIX8_RS10060
uniprot id: G8NTM9
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS23090
gene id: 682795:ACIX8_RS23090
uniprot id: G8NWR1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

682795:ACIX8 RS09330
gene id: 682795:ACIX8_RS09330
uniprot id: G8NS07
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

682795:ACIX8 RS16750
gene id: 682795:ACIX8_RS16750
uniprot id: G8NVL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS09400
gene id: 682795:ACIX8_RS09400
uniprot id: G8NS19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

682795:ACIX8 RS08090
gene id: 682795:ACIX8_RS08090
uniprot id: G8NNU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

682795:ACIX8 RS04740
gene id: 682795:ACIX8_RS04740
uniprot id: G8NUE7
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS20110
gene id: 682795:ACIX8_RS20110
uniprot id: G8NQ20
names: Similarity
messages: Belongs to the OsmC/Ohr family.

682795:ACIX8 RS15915
gene id: 682795:ACIX8_RS15915
uniprot id: G8NTW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

682795:ACIX8 RS23425
gene id: 682795:ACIX8_RS23425
uniprot id: G8NXL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

682795:ACIX8 RS14550
gene id: 682795:ACIX8_RS14550
uniprot id: G8NQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

682795:ACIX8 RS11375
gene id: 682795:ACIX8_RS11375
uniprot id: G8NW93
names: Similarity
messages: Belongs to the glutathione peroxidase family.

682795:ACIX8 RS21560
gene id: 682795:ACIX8_RS21560
uniprot id: G8NTC6
names: Similarity
messages: Belongs to the peptidase S1C family.

682795:ACIX8 RS06120
gene id: 682795:ACIX8_RS06120
uniprot id: G8NXZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

682795:ACIX8 RS08175
gene id: 682795:ACIX8_RS08175
uniprot id: G8NNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

682795:ACIX8 RS10120
gene id: 682795:ACIX8_RS10120
uniprot id: G8NTP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

682795:ACIX8 RS06830
gene id: 682795:ACIX8_RS06830
uniprot id: G8P007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

682795:ACIX8 RS13710
gene id: 682795:ACIX8_RS13710
uniprot id: G8NNW3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

682795:ACIX8 RS23995
gene id: 682795:ACIX8_RS23995
uniprot id: G8NZK8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

682795:ACIX8 RS22825
gene id: 682795:ACIX8_RS22825
uniprot id: G8NWK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

682795:ACIX8 RS15110
gene id: 682795:ACIX8_RS15110
uniprot id: G8NRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

682795:ACIX8 RS15870
gene id: 682795:ACIX8_RS15870
uniprot id: G8NT76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

682795:ACIX8 RS20375
gene id: 682795:ACIX8_RS20375
uniprot id: G8NQU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

682795:ACIX8 RS16355
gene id: 682795:ACIX8_RS16355
uniprot id: G8NUR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

682795:ACIX8 RS02905
gene id: 682795:ACIX8_RS02905
uniprot id: G8NQ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

682795:ACIX8 RS16105
gene id: 682795:ACIX8_RS16105
uniprot id: G8NTZ9
names: Similarity
messages: Belongs to the terpene synthase family.

682795:ACIX8 RS03090
gene id: 682795:ACIX8_RS03090
uniprot id: G8NQY4
names: Similarity
messages: Belongs to the UPF0145 family.

682795:ACIX8 RS03845
gene id: 682795:ACIX8_RS03845
uniprot id: G8NSM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS02265
gene id: 682795:ACIX8_RS02265
uniprot id: G8NNM7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

682795:ACIX8 RS13305
gene id: 682795:ACIX8_RS13305
uniprot id: G8P163
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

682795:ACIX8 RS09895
gene id: 682795:ACIX8_RS09895
uniprot id: G8NSX7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS04290
gene id: 682795:ACIX8_RS04290
uniprot id: G8NTI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

682795:ACIX8 RS09980
gene id: 682795:ACIX8_RS09980
uniprot id: G8NSZ3
names: Similarity
messages: Belongs to the peptidase S41A family.

682795:ACIX8 RS10040
gene id: 682795:ACIX8_RS10040
uniprot id: G8NT05
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

682795:ACIX8 RS01480
gene id: 682795:ACIX8_RS01480
uniprot id: G8P0P7
names: Similarity
messages: Belongs to the ParB family.

682795:ACIX8 RS00700
gene id: 682795:ACIX8_RS00700
uniprot id: G8NYT6
names: Similarity
messages: Belongs to the YciI family.

682795:ACIX8 RS05825
gene id: 682795:ACIX8_RS05825
uniprot id: G8NWY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

682795:ACIX8 RS24150
gene id: 682795:ACIX8_RS24150
uniprot id: G8NZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

682795:ACIX8 RS20855
gene id: 682795:ACIX8_RS20855
uniprot id: G8NRQ9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

682795:ACIX8 RS15310
gene id: 682795:ACIX8_RS15310
uniprot id: G8NS99
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

682795:ACIX8 RS00205
gene id: 682795:ACIX8_RS00205
uniprot id: G8NXQ5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

682795:ACIX8 RS10140
gene id: 682795:ACIX8_RS10140
uniprot id: G8NTP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

682795:ACIX8 RS10375
gene id: 682795:ACIX8_RS10375
uniprot id: G8NTU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

682795:ACIX8 RS23575
gene id: 682795:ACIX8_RS23575
uniprot id: G8NYI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

682795:ACIX8 RS22280
gene id: 682795:ACIX8_RS22280
uniprot id: G8NV13
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

682795:ACIX8 RS19680
gene id: 682795:ACIX8_RS19680
uniprot id: G8NP70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

682795:ACIX8 RS10400
gene id: 682795:ACIX8_RS10400
uniprot id: G8NTU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

682795:ACIX8 RS02425
gene id: 682795:ACIX8_RS02425
uniprot id: G8NPC3
names: Function
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.

682795:ACIX8 RS00010
gene id: 682795:ACIX8_RS00010
uniprot id: G8NWS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

682795:ACIX8 RS22380
gene id: 682795:ACIX8_RS22380
uniprot id: G8NV34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS10465
gene id: 682795:ACIX8_RS10465
uniprot id: G8NUI1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

682795:ACIX8 RS10600
gene id: 682795:ACIX8_RS10600
uniprot id: G8NUK8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

682795:ACIX8 RS07135
gene id: 682795:ACIX8_RS07135
uniprot id: G8P0T6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

682795:ACIX8 RS12485
gene id: 682795:ACIX8_RS12485
uniprot id: G8NZ89
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

682795:ACIX8 RS06375
gene id: 682795:ACIX8_RS06375
uniprot id: G8NYY0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

682795:ACIX8 RS15315
gene id: 682795:ACIX8_RS15315
uniprot id: G8NSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

682795:ACIX8 RS06845
gene id: 682795:ACIX8_RS06845
uniprot id: G8P010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

682795:ACIX8 RS05410
gene id: 682795:ACIX8_RS05410
uniprot id: G8NW18
names: Similarity
messages: Belongs to the AHA1 family.

682795:ACIX8 RS13605
gene id: 682795:ACIX8_RS13605
uniprot id: G8P1Z5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

682795:ACIX8 RS11645
gene id: 682795:ACIX8_RS11645
uniprot id: G8NX45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

682795:ACIX8 RS08705
gene id: 682795:ACIX8_RS08705
uniprot id: G8NQE1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

682795:ACIX8 RS19210
gene id: 682795:ACIX8_RS19210
uniprot id: G8P229
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

682795:ACIX8 RS04090
gene id: 682795:ACIX8_RS04090
uniprot id: G8NSS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS07560
gene id: 682795:ACIX8_RS07560
uniprot id: G8P1P4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS16890
gene id: 682795:ACIX8_RS16890
uniprot id: G8NVP2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

682795:ACIX8 RS01015
gene id: 682795:ACIX8_RS01015
uniprot id: G8NZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

682795:ACIX8 RS23380
gene id: 682795:ACIX8_RS23380
uniprot id: G8NXK8
names: Similarity
messages: Belongs to the UPF0303 family.

682795:ACIX8 RS13580
gene id: 682795:ACIX8_RS13580
uniprot id: G8P1Z0
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS14075
gene id: 682795:ACIX8_RS14075
uniprot id: G8NP30
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

682795:ACIX8 RS20600
gene id: 682795:ACIX8_RS20600
uniprot id: G8NRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

682795:ACIX8 RS04830
gene id: 682795:ACIX8_RS04830
uniprot id: G8NUG4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

682795:ACIX8 RS07440
gene id: 682795:ACIX8_RS07440
uniprot id: G8P1L8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

682795:ACIX8 RS02900
gene id: 682795:ACIX8_RS02900
uniprot id: G8NQ80
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

682795:ACIX8 RS09230
gene id: 682795:ACIX8_RS09230
uniprot id: G8NRB8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

682795:ACIX8 RS03535
gene id: 682795:ACIX8_RS03535
uniprot id: G8NRV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS00400
gene id: 682795:ACIX8_RS00400
uniprot id: G8NXU3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

682795:ACIX8 RS00295
gene id: 682795:ACIX8_RS00295
uniprot id: G8NXS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS02650
gene id: 682795:ACIX8_RS02650
uniprot id: G8NPG6
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

682795:ACIX8 RS05960
gene id: 682795:ACIX8_RS05960
uniprot id: G8NX17
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

682795:ACIX8 RS14670
gene id: 682795:ACIX8_RS14670
uniprot id: G8NQN1
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

682795:ACIX8 RS03850
gene id: 682795:ACIX8_RS03850
uniprot id: G8NSM5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

682795:ACIX8 RS05100
gene id: 682795:ACIX8_RS05100
uniprot id: G8NV85
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

682795:ACIX8 RS00440
gene id: 682795:ACIX8_RS00440
uniprot id: G8NXV0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

682795:ACIX8 RS00435
gene id: 682795:ACIX8_RS00435
uniprot id: G8NXU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

682795:ACIX8 RS08865
gene id: 682795:ACIX8_RS08865
uniprot id: G8NQH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

682795:ACIX8 RS16505
gene id: 682795:ACIX8_RS16505
uniprot id: G8NUU4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS19180
gene id: 682795:ACIX8_RS19180
uniprot id: G8P223
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS20320
gene id: 682795:ACIX8_RS20320
uniprot id: G8NQT1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

682795:ACIX8 RS22555
gene id: 682795:ACIX8_RS22555
uniprot id: G8NVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

682795:ACIX8 RS02780
gene id: 682795:ACIX8_RS02780
uniprot id: G8NQ56
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

682795:ACIX8 RS02725
gene id: 682795:ACIX8_RS02725
uniprot id: G8NQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

682795:ACIX8 RS00450
gene id: 682795:ACIX8_RS00450
uniprot id: G8NXV2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

682795:ACIX8 RS04115
gene id: 682795:ACIX8_RS04115
uniprot id: G8NSS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

682795:ACIX8 RS02445
gene id: 682795:ACIX8_RS02445
uniprot id: G8NPC8
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

682795:ACIX8 RS22290
gene id: 682795:ACIX8_RS22290
uniprot id: G8NV16
names: Similarity
messages: Belongs to the UPF0175 family.

682795:ACIX8 RS14585
gene id: 682795:ACIX8_RS14585
uniprot id: G8NQL5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS01935
gene id: 682795:ACIX8_RS01935
uniprot id: G8P1K9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS14095
gene id: 682795:ACIX8_RS14095
uniprot id: G8NPP9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS03140
gene id: 682795:ACIX8_RS03140
uniprot id: G8NQZ4
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

682795:ACIX8 RS04940
gene id: 682795:ACIX8_RS04940
uniprot id: G8NV52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

682795:ACIX8 RS14085
gene id: 682795:ACIX8_RS14085
uniprot id: G8NP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

682795:ACIX8 RS22860
gene id: 682795:ACIX8_RS22860
uniprot id: G8NWL3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

682795:ACIX8 RS04450
gene id: 682795:ACIX8_RS04450
uniprot id: G8NTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

682795:ACIX8 RS04150
gene id: 682795:ACIX8_RS04150
uniprot id: G8NTF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

682795:ACIX8 RS21725
gene id: 682795:ACIX8_RS21725
uniprot id: G8NU37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS20405
gene id: 682795:ACIX8_RS20405
uniprot id: G8NQU8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

682795:ACIX8 RS19150
gene id: 682795:ACIX8_RS19150
uniprot id: G8P217
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS12130
gene id: 682795:ACIX8_RS12130
uniprot id: G8NY80
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS19995
gene id: 682795:ACIX8_RS19995
uniprot id: G8NPZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

682795:ACIX8 RS08340
gene id: 682795:ACIX8_RS08340
uniprot id: G8NPL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

682795:ACIX8 RS10475
gene id: 682795:ACIX8_RS10475
uniprot id: G8NUI3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

682795:ACIX8 RS01890
gene id: 682795:ACIX8_RS01890
uniprot id: G8P1K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

682795:ACIX8 RS11765
gene id: 682795:ACIX8_RS11765
uniprot id: G8NX69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

682795:ACIX8 RS21235
gene id: 682795:ACIX8_RS21235
uniprot id: G8NSJ9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

682795:ACIX8 RS20860
gene id: 682795:ACIX8_RS20860
uniprot id: G8NRR0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

682795:ACIX8 RS09475
gene id: 682795:ACIX8_RS09475
uniprot id: G8NS33
names: Similarity
messages: Belongs to the sigma-54 factor family.

682795:ACIX8 RS01105
gene id: 682795:ACIX8_RS01105
uniprot id: G8NZV1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

682795:ACIX8 RS12110
gene id: 682795:ACIX8_RS12110
uniprot id: G8NY76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

682795:ACIX8 RS08360
gene id: 682795:ACIX8_RS08360
uniprot id: G8NPL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS01290
gene id: 682795:ACIX8_RS01290
uniprot id: G8P0K7
names: Similarity
messages: Belongs to the peptidase M13 family.

682795:ACIX8 RS03095
gene id: 682795:ACIX8_RS03095
uniprot id: G8NQY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS07125
gene id: 682795:ACIX8_RS07125
uniprot id: G8P0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

682795:ACIX8 RS08230
gene id: 682795:ACIX8_RS08230
uniprot id: G8NPI6
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

682795:ACIX8 RS17485
gene id: 682795:ACIX8_RS17485
uniprot id: G8NXC4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS23115
gene id: 682795:ACIX8_RS23115
uniprot id: G8NWR5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02040
gene id: 682795:ACIX8_RS02040
uniprot id: G8NNI4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

682795:ACIX8 RS09445
gene id: 682795:ACIX8_RS09445
uniprot id: G8NS27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

682795:ACIX8 RS22435
gene id: 682795:ACIX8_RS22435
uniprot id: G8NVR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS19230
gene id: 682795:ACIX8_RS19230
uniprot id: G8P233
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

682795:ACIX8 RS10250
gene id: 682795:ACIX8_RS10250
uniprot id: G8NTR7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

682795:ACIX8 RS19155
gene id: 682795:ACIX8_RS19155
uniprot id: G8P218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

682795:ACIX8 RS06535
gene id: 682795:ACIX8_RS06535
uniprot id: G8NZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

682795:ACIX8 RS02855
gene id: 682795:ACIX8_RS02855
uniprot id: G8NQ71
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

682795:ACIX8 RS23170
gene id: 682795:ACIX8_RS23170
uniprot id: G8NXG7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS09585
gene id: 682795:ACIX8_RS09585
uniprot id: G8NS51
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS17685
gene id: 682795:ACIX8_RS17685
uniprot id: G8NXG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

682795:ACIX8 RS02585
gene id: 682795:ACIX8_RS02585
uniprot id: G8NPF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

682795:ACIX8 RS05680
gene id: 682795:ACIX8_RS05680
uniprot id: G8NWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

682795:ACIX8 RS00890
gene id: 682795:ACIX8_RS00890
uniprot id: G8NZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

682795:ACIX8 RS01945
gene id: 682795:ACIX8_RS01945
uniprot id: G8P1L1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

682795:ACIX8 RS00710
gene id: 682795:ACIX8_RS00710
uniprot id: G8NYT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS03210
gene id: 682795:ACIX8_RS03210
uniprot id: G8NR08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS15125
gene id: 682795:ACIX8_RS15125
uniprot id: G8NRJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

682795:ACIX8 RS22945
gene id: 682795:ACIX8_RS22945
uniprot id: G8NWN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

682795:ACIX8 RS17090
gene id: 682795:ACIX8_RS17090
uniprot id: G8NWF1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS05095
gene id: 682795:ACIX8_RS05095
uniprot id: G8NV84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

682795:ACIX8 RS16475
gene id: 682795:ACIX8_RS16475
uniprot id: G8NUT8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

682795:ACIX8 RS10295
gene id: 682795:ACIX8_RS10295
uniprot id: G8NTS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

682795:ACIX8 RS07785
gene id: 682795:ACIX8_RS07785
uniprot id: G8P1T9
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS14060
gene id: 682795:ACIX8_RS14060
uniprot id: G8NP27
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS24060
gene id: 682795:ACIX8_RS24060
uniprot id: G8NZM1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

682795:ACIX8 RS12010
gene id: 682795:ACIX8_RS12010
uniprot id: G8NY56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

682795:ACIX8 RS07930
gene id: 682795:ACIX8_RS07930
uniprot id: G8NNR3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

682795:ACIX8 RS03295
gene id: 682795:ACIX8_RS03295
uniprot id: G8NR28
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

682795:ACIX8 RS13400
gene id: 682795:ACIX8_RS13400
uniprot id: G8P1V4
names: Similarity
messages: Belongs to the glycosyl hydrolase.

682795:ACIX8 RS19160
gene id: 682795:ACIX8_RS19160
uniprot id: G8P219
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS23560
gene id: 682795:ACIX8_RS23560
uniprot id: G8NYI1
names: Similarity
messages: Belongs to the DapA family.

682795:ACIX8 RS03545
gene id: 682795:ACIX8_RS03545
uniprot id: G8NRV3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

682795:ACIX8 RS10490
gene id: 682795:ACIX8_RS10490
uniprot id: G8NUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

682795:ACIX8 RS22500
gene id: 682795:ACIX8_RS22500
uniprot id: G8NVS5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS18925
gene id: 682795:ACIX8_RS18925
uniprot id: G8P1A1
names: Similarity
messages: Belongs to the frataxin family.

682795:ACIX8 RS10805
gene id: 682795:ACIX8_RS10805
uniprot id: G8NVB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS18320
gene id: 682795:ACIX8_RS18320
uniprot id: G8NZG8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS15405
gene id: 682795:ACIX8_RS15405
uniprot id: G8NSB8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS19395
gene id: 682795:ACIX8_RS19395
uniprot id: G8P267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

682795:ACIX8 RS13130
gene id: 682795:ACIX8_RS13130
uniprot id: G8P126
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

682795:ACIX8 RS18605
gene id: 682795:ACIX8_RS18605
uniprot id: G8P0G5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

682795:ACIX8 RS18145
gene id: 682795:ACIX8_RS18145
uniprot id: G8NZD2
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS23745
gene id: 682795:ACIX8_RS23745
uniprot id: G8NYL9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

682795:ACIX8 RS20540
gene id: 682795:ACIX8_RS20540
uniprot id: G8NQX3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

682795:ACIX8 RS01165
gene id: 682795:ACIX8_RS01165
uniprot id: G8NZW3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

682795:ACIX8 RS04205
gene id: 682795:ACIX8_RS04205
uniprot id: G8NTG3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS07750
gene id: 682795:ACIX8_RS07750
uniprot id: G8P1T2
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS01770
gene id: 682795:ACIX8_RS01770
uniprot id: G8P1H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

682795:ACIX8 RS04620
gene id: 682795:ACIX8_RS04620
uniprot id: G8NUC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

682795:ACIX8 RS05020
gene id: 682795:ACIX8_RS05020
uniprot id: G8NV68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

682795:ACIX8 RS15265
gene id: 682795:ACIX8_RS15265
uniprot id: G8NS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

682795:ACIX8 RS05540
gene id: 682795:ACIX8_RS05540
uniprot id: G8NW42
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS22660
gene id: 682795:ACIX8_RS22660
uniprot id: G8NVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS06210
gene id: 682795:ACIX8_RS06210
uniprot id: G8NY08
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

682795:ACIX8 RS12285
gene id: 682795:ACIX8_RS12285
uniprot id: G8NZ49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS07810
gene id: 682795:ACIX8_RS07810
uniprot id: G8P1U1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS06170
gene id: 682795:ACIX8_RS06170
uniprot id: G8NY00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

682795:ACIX8 RS17620
gene id: 682795:ACIX8_RS17620
uniprot id: G8NXF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

682795:ACIX8 RS19170
gene id: 682795:ACIX8_RS19170
uniprot id: G8P221
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS21655
gene id: 682795:ACIX8_RS21655
uniprot id: G8NTE5
names: Similarity
messages: Belongs to the XFP family.

682795:ACIX8 RS06625
gene id: 682795:ACIX8_RS06625
uniprot id: G8NZ29
names: Subcellular Location Annotation
messages: Periplasm

682795:ACIX8 RS02505
gene id: 682795:ACIX8_RS02505
uniprot id: G8NPD9
names: Similarity
messages: Belongs to the RutC family.

682795:ACIX8 RS15305
gene id: 682795:ACIX8_RS15305
uniprot id: G8NS98
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

682795:ACIX8 RS03575
gene id: 682795:ACIX8_RS03575
uniprot id: G8NRV9
names: Subunit
messages: Homotetramer.

682795:ACIX8 RS00325
gene id: 682795:ACIX8_RS00325
uniprot id: G8NXS9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

682795:ACIX8 RS23270
gene id: 682795:ACIX8_RS23270
uniprot id: G8NXI7
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

682795:ACIX8 RS06690
gene id: 682795:ACIX8_RS06690
uniprot id: G8NZ42
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

682795:ACIX8 RS15190
gene id: 682795:ACIX8_RS15190
uniprot id: G8NS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

682795:ACIX8 RS15655
gene id: 682795:ACIX8_RS15655
uniprot id: G8NT33
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS07215
gene id: 682795:ACIX8_RS07215
uniprot id: G8P0V3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

682795:ACIX8 RS16565
gene id: 682795:ACIX8_RS16565
uniprot id: G8NUV6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

682795:ACIX8 RS01620
gene id: 682795:ACIX8_RS01620
uniprot id: G8P1E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

682795:ACIX8 RS02940
gene id: 682795:ACIX8_RS02940
uniprot id: G8NQ88
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

682795:ACIX8 RS18290
gene id: 682795:ACIX8_RS18290
uniprot id: G8NZG2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

682795:ACIX8 RS06700
gene id: 682795:ACIX8_RS06700
uniprot id: G8NZ44
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS02080
gene id: 682795:ACIX8_RS02080
uniprot id: G8NNJ2
names: Similarity
messages: Belongs to the HSP15 family.

682795:ACIX8 RS12495
gene id: 682795:ACIX8_RS12495
uniprot id: G8NZ91
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS06380
gene id: 682795:ACIX8_RS06380
uniprot id: G8NYY1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

682795:ACIX8 RS06635
gene id: 682795:ACIX8_RS06635
uniprot id: G8NZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

682795:ACIX8 RS02290
gene id: 682795:ACIX8_RS02290
uniprot id: G8NNN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

682795:ACIX8 RS04125
gene id: 682795:ACIX8_RS04125
uniprot id: G8NST0
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS21340
gene id: 682795:ACIX8_RS21340
uniprot id: G8NT81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS02535
gene id: 682795:ACIX8_RS02535
uniprot id: G8NPE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

682795:ACIX8 RS08065
gene id: 682795:ACIX8_RS08065
uniprot id: G8NNU1
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08930
gene id: 682795:ACIX8_RS08930
uniprot id: G8NQI4
names: Similarity
messages: Belongs to the CobH/CbiC family.

682795:ACIX8 RS05365
gene id: 682795:ACIX8_RS05365
uniprot id: G8NW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

682795:ACIX8 RS06475
gene id: 682795:ACIX8_RS06475
uniprot id: G8NZ00
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

682795:ACIX8 RS08000
gene id: 682795:ACIX8_RS08000
uniprot id: G8NNS8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

682795:ACIX8 RS06355
gene id: 682795:ACIX8_RS06355
uniprot id: G8NYX5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

682795:ACIX8 RS03375
gene id: 682795:ACIX8_RS03375
uniprot id: G8NR45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

682795:ACIX8 RS08135
gene id: 682795:ACIX8_RS08135
uniprot id: G8NNV4
names: Similarity
messages: Belongs to the SCO1/2 family.

682795:ACIX8 RS16850
gene id: 682795:ACIX8_RS16850
uniprot id: G8NVN4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

682795:ACIX8 RS08935
gene id: 682795:ACIX8_RS08935
uniprot id: G8NR56
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

682795:ACIX8 RS21400
gene id: 682795:ACIX8_RS21400
uniprot id: G8NT94
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

682795:ACIX8 RS20430
gene id: 682795:ACIX8_RS20430
uniprot id: G8NQV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

682795:ACIX8 RS20455
gene id: 682795:ACIX8_RS20455
uniprot id: G8NQV7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

682795:ACIX8 RS03565
gene id: 682795:ACIX8_RS03565
uniprot id: G8NRV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

682795:ACIX8 RS14350
gene id: 682795:ACIX8_RS14350
uniprot id: G8NPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS13470
gene id: 682795:ACIX8_RS13470
uniprot id: G8P1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

682795:ACIX8 RS23785
gene id: 682795:ACIX8_RS23785
uniprot id: G8NYM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS12030
gene id: 682795:ACIX8_RS12030
uniprot id: G8NY60
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

682795:ACIX8 RS18300
gene id: 682795:ACIX8_RS18300
uniprot id: G8NZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

682795:ACIX8 RS07115
gene id: 682795:ACIX8_RS07115
uniprot id: G8P0T2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS08145
gene id: 682795:ACIX8_RS08145
uniprot id: G8NNV6
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS15845
gene id: 682795:ACIX8_RS15845
uniprot id: G8NT71
names: Similarity
messages: Belongs to the ClpA/ClpB family.

682795:ACIX8 RS05185
gene id: 682795:ACIX8_RS05185
uniprot id: G8NVA2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

682795:ACIX8 RS08385
gene id: 682795:ACIX8_RS08385
uniprot id: G8NPL8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

682795:ACIX8 RS10035
gene id: 682795:ACIX8_RS10035
uniprot id: G8NT04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

682795:ACIX8 RS23200
gene id: 682795:ACIX8_RS23200
uniprot id: G8NXH3
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02875
gene id: 682795:ACIX8_RS02875
uniprot id: G8NQ75
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

682795:ACIX8 RS11260
gene id: 682795:ACIX8_RS11260
uniprot id: G8NW69
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

682795:ACIX8 RS18595
gene id: 682795:ACIX8_RS18595
uniprot id: G8P0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

682795:ACIX8 RS10025
gene id: 682795:ACIX8_RS10025
uniprot id: G8NT02
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

682795:ACIX8 RS05745
gene id: 682795:ACIX8_RS05745
uniprot id: G8NWX3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

682795:ACIX8 RS02785
gene id: 682795:ACIX8_RS02785
uniprot id: G8NQ57
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

682795:ACIX8 RS24090
gene id: 682795:ACIX8_RS24090
uniprot id: G8NZM6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

682795:ACIX8 RS13405
gene id: 682795:ACIX8_RS13405
uniprot id: G8P1V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

682795:ACIX8 RS03275
gene id: 682795:ACIX8_RS03275
uniprot id: G8NR23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

682795:ACIX8 RS06045
gene id: 682795:ACIX8_RS06045
uniprot id: G8NXX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

682795:ACIX8 RS11320
gene id: 682795:ACIX8_RS11320
uniprot id: G8NW81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

682795:ACIX8 RS03120
gene id: 682795:ACIX8_RS03120
uniprot id: G8NQZ0
names: Similarity
messages: Belongs to the aldose epimerase family.

682795:ACIX8 RS07060
gene id: 682795:ACIX8_RS07060
uniprot id: G8P052
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

682795:ACIX8 RS19775
gene id: 682795:ACIX8_RS19775
uniprot id: G8NP87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

682795:ACIX8 RS20460
gene id: 682795:ACIX8_RS20460
uniprot id: G8NQV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

682795:ACIX8 RS21625
gene id: 682795:ACIX8_RS21625
uniprot id: G8NTD9
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS04040
gene id: 682795:ACIX8_RS04040
uniprot id: G8NSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

682795:ACIX8 RS17040
gene id: 682795:ACIX8_RS17040
uniprot id: G8NWE1
names: Similarity
messages: Belongs to the fabD family.

682795:ACIX8 RS06660
gene id: 682795:ACIX8_RS06660
uniprot id: G8NZ36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

682795:ACIX8 RS20570
gene id: 682795:ACIX8_RS20570
uniprot id: G8NQX9
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

682795:ACIX8 RS03870
gene id: 682795:ACIX8_RS03870
uniprot id: G8NSM9
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

682795:ACIX8 RS22680
gene id: 682795:ACIX8_RS22680
uniprot id: G8NVW1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

682795:ACIX8 RS24240
gene id: 682795:ACIX8_RS24240
uniprot id: G8NZQ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

682795:ACIX8 RS15690
gene id: 682795:ACIX8_RS15690
uniprot id: G8NT39
names: Similarity
messages: Belongs to the RecA family.

682795:ACIX8 RS12970
gene id: 682795:ACIX8_RS12970
uniprot id: G8P0C4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS19220
gene id: 682795:ACIX8_RS19220
uniprot id: G8P231
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

682795:ACIX8 RS19830
gene id: 682795:ACIX8_RS19830
uniprot id: G8NP98
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS02600
gene id: 682795:ACIX8_RS02600
uniprot id: G8NPF7
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS16425
gene id: 682795:ACIX8_RS16425
uniprot id: G8NUS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

682795:ACIX8 RS07975
gene id: 682795:ACIX8_RS07975
uniprot id: G8NNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS00555
gene id: 682795:ACIX8_RS00555
uniprot id: G8NYQ6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

682795:ACIX8 RS20135
gene id: 682795:ACIX8_RS20135
uniprot id: G8NQ25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS23295
gene id: 682795:ACIX8_RS23295
uniprot id: G8NXJ2
names: Similarity
messages: Belongs to the Nth/MutY family.

682795:ACIX8 RS13285
gene id: 682795:ACIX8_RS13285
uniprot id: G8P159
names: Similarity
messages: Belongs to the thioredoxin family.

682795:ACIX8 RS18995
gene id: 682795:ACIX8_RS18995
uniprot id: G8P1B5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS00785
gene id: 682795:ACIX8_RS00785
uniprot id: G8NYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

682795:ACIX8 RS14975
gene id: 682795:ACIX8_RS14975
uniprot id: G8NRG4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS00780
gene id: 682795:ACIX8_RS00780
uniprot id: G8NYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

682795:ACIX8 RS22220
gene id: 682795:ACIX8_RS22220
uniprot id: G8NV01
names: Subcellular Location Annotation
messages: Secreted

682795:ACIX8 RS19165
gene id: 682795:ACIX8_RS19165
uniprot id: G8P220
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

682795:ACIX8 RS03905
gene id: 682795:ACIX8_RS03905
uniprot id: G8NSN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

682795:ACIX8 RS02845
gene id: 682795:ACIX8_RS02845
uniprot id: G8NQ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

682795:ACIX8 RS16200
gene id: 682795:ACIX8_RS16200
uniprot id: G8NU18
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

682795:ACIX8 RS21675
gene id: 682795:ACIX8_RS21675
uniprot id: G8NTE9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS15435
gene id: 682795:ACIX8_RS15435
uniprot id: G8NSC4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

682795:ACIX8 RS13010
gene id: 682795:ACIX8_RS13010
uniprot id: G8P102
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

682795:ACIX8 RS10150
gene id: 682795:ACIX8_RS10150
uniprot id: G8NTP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

682795:ACIX8 RS06585
gene id: 682795:ACIX8_RS06585
uniprot id: G8NZ21
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS04405
gene id: 682795:ACIX8_RS04405
uniprot id: G8NTK4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS07250
gene id: 682795:ACIX8_RS07250
uniprot id: G8P0V9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

682795:ACIX8 RS08095
gene id: 682795:ACIX8_RS08095
uniprot id: G8NNU6
names: Similarity
messages: Belongs to the threonine aldolase family.

682795:ACIX8 RS18165
gene id: 682795:ACIX8_RS18165
uniprot id: G8NZD5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

682795:ACIX8 RS17990
gene id: 682795:ACIX8_RS17990
uniprot id: G8NYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

682795:ACIX8 RS24030
gene id: 682795:ACIX8_RS24030
uniprot id: G8NZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

682795:ACIX8 RS13890
gene id: 682795:ACIX8_RS13890
uniprot id: G8NNZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

682795:ACIX8 RS23155
gene id: 682795:ACIX8_RS23155
uniprot id: G8NWS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

682795:ACIX8 RS21750
gene id: 682795:ACIX8_RS21750
uniprot id: G8NU42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

682795:ACIX8 RS18915
gene id: 682795:ACIX8_RS18915
uniprot id: G8NRW7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

682795:ACIX8 RS08155
gene id: 682795:ACIX8_RS08155
uniprot id: G8NNV8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

682795:ACIX8 RS22835
gene id: 682795:ACIX8_RS22835
uniprot id: G8NWK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

682795:ACIX8 RS19225
gene id: 682795:ACIX8_RS19225
uniprot id: G8P232
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

682795:ACIX8 RS05090
gene id: 682795:ACIX8_RS05090
uniprot id: G8NV82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

682795:ACIX8 RS12570
gene id: 682795:ACIX8_RS12570
uniprot id: G8NZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

682795:ACIX8 RS21065
gene id: 682795:ACIX8_RS21065
uniprot id: G8NSG5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

682795:ACIX8 RS19115
gene id: 682795:ACIX8_RS19115
uniprot id: G8P1D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

682795:ACIX8 RS03645
gene id: 682795:ACIX8_RS03645
uniprot id: G8NRW7
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

682795:ACIX8 RS19555
gene id: 682795:ACIX8_RS19555
uniprot id: G8NP45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS18050
gene id: 682795:ACIX8_RS18050
uniprot id: G8NZB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

682795:ACIX8 RS11875
gene id: 682795:ACIX8_RS11875
uniprot id: G8NX90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS15300
gene id: 682795:ACIX8_RS15300
uniprot id: G8NS97
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

682795:ACIX8 RS00925
gene id: 682795:ACIX8_RS00925
uniprot id: G8NZR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

682795:ACIX8 RS20260
gene id: 682795:ACIX8_RS20260
uniprot id: G8NQR9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

682795:ACIX8 RS07255
gene id: 682795:ACIX8_RS07255
uniprot id: G8P0W0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS09180
gene id: 682795:ACIX8_RS09180
uniprot id: G8NRA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

682795:ACIX8 RS11805
gene id: 682795:ACIX8_RS11805
uniprot id: G8NX76
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

682795:ACIX8 RS20000
gene id: 682795:ACIX8_RS20000
uniprot id: G8NPZ8
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS05660
gene id: 682795:ACIX8_RS05660
uniprot id: G8NWV7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

682795:ACIX8 RS17910
gene id: 682795:ACIX8_RS17910
uniprot id: G8NYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

682795:ACIX8 RS02710
gene id: 682795:ACIX8_RS02710
uniprot id: G8NQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

682795:ACIX8 RS13330
gene id: 682795:ACIX8_RS13330
uniprot id: G8P168
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS03305
gene id: 682795:ACIX8_RS03305
uniprot id: G8NR30
names: Similarity
messages: Belongs to the GSP E family.

682795:ACIX8 RS00645
gene id: 682795:ACIX8_RS00645
uniprot id: G8NYS5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

682795:ACIX8 RS22990
gene id: 682795:ACIX8_RS22990
uniprot id: G8NWP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

682795:ACIX8 RS21870
gene id: 682795:ACIX8_RS21870
uniprot id: G8NU67
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

682795:ACIX8 RS03060
gene id: 682795:ACIX8_RS03060
uniprot id: G8NQA7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS23015
gene id: 682795:ACIX8_RS23015
uniprot id: G8NWP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

682795:ACIX8 RS23955
gene id: 682795:ACIX8_RS23955
uniprot id: G8NZK0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

682795:ACIX8 RS16560
gene id: 682795:ACIX8_RS16560
uniprot id: G8NUV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

682795:ACIX8 RS05380
gene id: 682795:ACIX8_RS05380
uniprot id: G8NW12
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

682795:ACIX8 RS18175
gene id: 682795:ACIX8_RS18175
uniprot id: G8NZD7
names: Similarity
messages: Belongs to the peptidase M13 family.

682795:ACIX8 RS03405
gene id: 682795:ACIX8_RS03405
uniprot id: G8NR51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

682795:ACIX8 RS19235
gene id: 682795:ACIX8_RS19235
uniprot id: G8P234
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS06935
gene id: 682795:ACIX8_RS06935
uniprot id: G8P028
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS20805
gene id: 682795:ACIX8_RS20805
uniprot id: G8NRP8
names: Similarity
messages: Belongs to the HypD family.

682795:ACIX8 RS13395
gene id: 682795:ACIX8_RS13395
uniprot id: G8P1V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

682795:ACIX8 RS02765
gene id: 682795:ACIX8_RS02765
uniprot id: G8NQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

682795:ACIX8 RS01100
gene id: 682795:ACIX8_RS01100
uniprot id: G8NZV0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

682795:ACIX8 RS17860
gene id: 682795:ACIX8_RS17860
uniprot id: G8NYD7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

682795:ACIX8 RS22345
gene id: 682795:ACIX8_RS22345
uniprot id: G8NV27
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS22075
gene id: 682795:ACIX8_RS22075
uniprot id: G8NUX4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

682795:ACIX8 RS08240
gene id: 682795:ACIX8_RS08240
uniprot id: G8NPI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

682795:ACIX8 RS10155
gene id: 682795:ACIX8_RS10155
uniprot id: G8NTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

682795:ACIX8 RS06650
gene id: 682795:ACIX8_RS06650
uniprot id: G8NZ34
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

682795:ACIX8 RS01625
gene id: 682795:ACIX8_RS01625
uniprot id: G8P1E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

682795:ACIX8 RS11715
gene id: 682795:ACIX8_RS11715
uniprot id: G8NX59
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

682795:ACIX8 RS07830
gene id: 682795:ACIX8_RS07830
uniprot id: G8NNP5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

682795:ACIX8 RS00765
gene id: 682795:ACIX8_RS00765
uniprot id: G8NYU7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

682795:ACIX8 RS24015
gene id: 682795:ACIX8_RS24015
uniprot id: G8NZL2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

682795:ACIX8 RS16185
gene id: 682795:ACIX8_RS16185
uniprot id: G8NU15
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

682795:ACIX8 RS05075
gene id: 682795:ACIX8_RS05075
uniprot id: G8NV79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

682795:ACIX8 RS12135
gene id: 682795:ACIX8_RS12135
uniprot id: G8NY81
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

682795:ACIX8 RS21735
gene id: 682795:ACIX8_RS21735
uniprot id: G8NU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

682795:ACIX8 RS10635
gene id: 682795:ACIX8_RS10635
uniprot id: G8NUL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

682795:ACIX8 RS19145
gene id: 682795:ACIX8_RS19145
uniprot id: G8P216
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS12885
gene id: 682795:ACIX8_RS12885
uniprot id: G8P0A8
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

682795:ACIX8 RS09220
gene id: 682795:ACIX8_RS09220
uniprot id: G8NRB6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS08635
gene id: 682795:ACIX8_RS08635
uniprot id: G8NQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

682795:ACIX8 RS24225
gene id: 682795:ACIX8_RS24225
uniprot id: G8NZQ3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

682795:ACIX8 RS10655
gene id: 682795:ACIX8_RS10655
uniprot id: G8NUL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS01980
gene id: 682795:ACIX8_RS01980
uniprot id: G8NNH2
names: Similarity
messages: Belongs to the Lgt family.

682795:ACIX8 RS12975
gene id: 682795:ACIX8_RS12975
uniprot id: G8P0C5
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS07550
gene id: 682795:ACIX8_RS07550
uniprot id: G8P1P2
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

682795:ACIX8 RS12510
gene id: 682795:ACIX8_RS12510
uniprot id: G8NZ94
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

682795:ACIX8 RS10455
gene id: 682795:ACIX8_RS10455
uniprot id: G8NUH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

682795:ACIX8 RS06065
gene id: 682795:ACIX8_RS06065
uniprot id: G8NXX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

682795:ACIX8 RS09945
gene id: 682795:ACIX8_RS09945
uniprot id: G8NSX5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

682795:ACIX8 RS21975
gene id: 682795:ACIX8_RS21975
uniprot id: G8NU89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

682795:ACIX8 RS00315
gene id: 682795:ACIX8_RS00315
uniprot id: G8NXS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

682795:ACIX8 RS00860
gene id: 682795:ACIX8_RS00860
uniprot id: G8NYW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

682795:ACIX8 RS09970
gene id: 682795:ACIX8_RS09970
uniprot id: G8NSZ2
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

682795:ACIX8 RS00280
gene id: 682795:ACIX8_RS00280
uniprot id: G8NXS0
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

682795:ACIX8 RS22635
gene id: 682795:ACIX8_RS22635
uniprot id: G8NVV2
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS00020
gene id: 682795:ACIX8_RS00020
uniprot id: G8NWS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

682795:ACIX8 RS20400
gene id: 682795:ACIX8_RS20400
uniprot id: G8NQU7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

682795:ACIX8 RS19380
gene id: 682795:ACIX8_RS19380
uniprot id: G8P263
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

682795:ACIX8 RS14425
gene id: 682795:ACIX8_RS14425
uniprot id: G8NPW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

682795:ACIX8 RS18055
gene id: 682795:ACIX8_RS18055
uniprot id: G8NZB4
names: Similarity
messages: Belongs to the AHA1 family.

682795:ACIX8 RS21245
gene id: 682795:ACIX8_RS21245
uniprot id: G8NSK1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

682795:ACIX8 RS17145
gene id: 682795:ACIX8_RS17145
uniprot id: G8NWG3
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS02375
gene id: 682795:ACIX8_RS02375
uniprot id: G8NPB4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS20315
gene id: 682795:ACIX8_RS20315
uniprot id: G8NQT0
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS21120
gene id: 682795:ACIX8_RS21120
uniprot id: G8NSH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS10430
gene id: 682795:ACIX8_RS10430
uniprot id: G8NUH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

682795:ACIX8 RS04750
gene id: 682795:ACIX8_RS04750
uniprot id: G8NUE9
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS16520
gene id: 682795:ACIX8_RS16520
uniprot id: G8NUU7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

682795:ACIX8 RS10955
gene id: 682795:ACIX8_RS10955
uniprot id: G8NVE0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

682795:ACIX8 RS03910
gene id: 682795:ACIX8_RS03910
uniprot id: G8NSN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

682795:ACIX8 RS15815
gene id: 682795:ACIX8_RS15815
uniprot id: G8NT65
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS09265
gene id: 682795:ACIX8_RS09265
uniprot id: G8NRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

682795:ACIX8 RS22310
gene id: 682795:ACIX8_RS22310
uniprot id: G8NV20
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

682795:ACIX8 RS13630
gene id: 682795:ACIX8_RS13630
uniprot id: G8NNM6
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

682795:ACIX8 RS18540
gene id: 682795:ACIX8_RS18540
uniprot id: G8P0F1
names: Similarity
messages: Belongs to the group II decarboxylase family.

682795:ACIX8 RS04015
gene id: 682795:ACIX8_RS04015
uniprot id: G8NSQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

682795:ACIX8 RS11030
gene id: 682795:ACIX8_RS11030
uniprot id: G8NVF5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

682795:ACIX8 RS13200
gene id: 682795:ACIX8_RS13200
uniprot id: G8P142
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS23705
gene id: 682795:ACIX8_RS23705
uniprot id: G8NYL1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

682795:ACIX8 RS14465
gene id: 682795:ACIX8_RS14465
uniprot id: G8NQI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

682795:ACIX8 RS18010
gene id: 682795:ACIX8_RS18010
uniprot id: G8NYG7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS06850
gene id: 682795:ACIX8_RS06850
uniprot id: G8P011
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

682795:ACIX8 RS11195
gene id: 682795:ACIX8_RS11195
uniprot id: G8NW56
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

682795:ACIX8 RS22605
gene id: 682795:ACIX8_RS22605
uniprot id: G8NVU6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS20515
gene id: 682795:ACIX8_RS20515
uniprot id: G8NQW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

682795:ACIX8 RS02490
gene id: 682795:ACIX8_RS02490
uniprot id: G8NPD6
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

682795:ACIX8 RS11800
gene id: 682795:ACIX8_RS11800
uniprot id: G8NX75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS23150
gene id: 682795:ACIX8_RS23150
uniprot id: G8NWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

682795:ACIX8 RS19285
gene id: 682795:ACIX8_RS19285
uniprot id: G8P244
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

682795:ACIX8 RS25535
gene id: 682795:ACIX8_RS25535
uniprot id: G8NSM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

682795:ACIX8 RS23430
gene id: 682795:ACIX8_RS23430
uniprot id: G8NXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

682795:ACIX8 RS18370
gene id: 682795:ACIX8_RS18370
uniprot id: G8NZH6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS02825
gene id: 682795:ACIX8_RS02825
uniprot id: G8NSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

682795:ACIX8 RS04335
gene id: 682795:ACIX8_RS04335
uniprot id: G8NTJ0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

682795:ACIX8 RS17235
gene id: 682795:ACIX8_RS17235
uniprot id: G8NWI1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

682795:ACIX8 RS23000
gene id: 682795:ACIX8_RS23000
uniprot id: G8NWP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

682795:ACIX8 RS09550
gene id: 682795:ACIX8_RS09550
uniprot id: G8NS46
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS07705
gene id: 682795:ACIX8_RS07705
uniprot id: G8P1S3
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS10870
gene id: 682795:ACIX8_RS10870
uniprot id: G8NVC8
names: Function
names: Subcellular Location Annotation
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane

682795:ACIX8 RS18825
gene id: 682795:ACIX8_RS18825
uniprot id: G8P179
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

682795:ACIX8 RS22080
gene id: 682795:ACIX8_RS22080
uniprot id: G8NUX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

682795:ACIX8 RS16740
gene id: 682795:ACIX8_RS16740
uniprot id: G8NVL0
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS15930
gene id: 682795:ACIX8_RS15930
uniprot id: G8NTW4
names: Subcellular Location Annotation
messages: Membrane

682795:ACIX8 RS08285
gene id: 682795:ACIX8_RS08285
uniprot id: G8NPJ8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

682795:ACIX8 RS15350
gene id: 682795:ACIX8_RS15350
uniprot id: G8NSA7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

682795:ACIX8 RS07735
gene id: 682795:ACIX8_RS07735
uniprot id: G8P1S9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

682795:ACIX8 RS21585
gene id: 682795:ACIX8_RS21585
uniprot id: G8NTD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

682795:ACIX8 RS13550
gene id: 682795:ACIX8_RS13550
uniprot id: G8P1Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

682795:ACIX8 RS02850
gene id: 682795:ACIX8_RS02850
uniprot id: G8NQ70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

682795:ACIX8 RS21915
gene id: 682795:ACIX8_RS21915
uniprot id: G8NU76
names: Cofactor
messages: Binds 1 zinc ion per subunit.