679937:BCOP RS04860
gene id: 679937:BCOP_RS04860
uniprot id: F3ZU39
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS09145
gene id: 679937:BCOP_RS09145
uniprot id: F3ZRN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

679937:BCOP RS03840
gene id: 679937:BCOP_RS03840
uniprot id: F3ZSS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

679937:BCOP RS07225
gene id: 679937:BCOP_RS07225
uniprot id: F3ZPD6
names: Similarity
messages: Belongs to the fabD family.

679937:BCOP RS04920
gene id: 679937:BCOP_RS04920
uniprot id: F3ZU43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

679937:BCOP RS12120
gene id: 679937:BCOP_RS12120
uniprot id: F3ZNJ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

679937:BCOP RS09280
gene id: 679937:BCOP_RS09280
uniprot id: F3ZRR2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS06065
gene id: 679937:BCOP_RS06065
uniprot id: F3ZUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

679937:BCOP RS04250
gene id: 679937:BCOP_RS04250
uniprot id: F3ZTE1
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: In the C-terminal section; belongs to the NAD synthetase family.

679937:BCOP RS09015
gene id: 679937:BCOP_RS09015
uniprot id: F3ZRE3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

679937:BCOP RS08370
gene id: 679937:BCOP_RS08370
uniprot id: F3ZQM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

679937:BCOP RS06255
gene id: 679937:BCOP_RS06255
uniprot id: F3ZUV1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

679937:BCOP RS02665
gene id: 679937:BCOP_RS02665
uniprot id: F3ZRL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

679937:BCOP RS02620
gene id: 679937:BCOP_RS02620
uniprot id: F3ZRK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

679937:BCOP RS01580
gene id: 679937:BCOP_RS01580
uniprot id: F3ZQF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

679937:BCOP RS04780
gene id: 679937:BCOP_RS04780
uniprot id: F3ZU25
names: Function
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.

679937:BCOP RS01220
gene id: 679937:BCOP_RS01220
uniprot id: F3ZQ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

679937:BCOP RS11235
gene id: 679937:BCOP_RS11235
uniprot id: F3ZTY6
names: Similarity
messages: Belongs to the UPF0047 family.

679937:BCOP RS03530
gene id: 679937:BCOP_RS03530
uniprot id: F3ZSM6
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

679937:BCOP RS02240
gene id: 679937:BCOP_RS02240
uniprot id: F3ZR67
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

679937:BCOP RS10485
gene id: 679937:BCOP_RS10485
uniprot id: F3ZSY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS08705
gene id: 679937:BCOP_RS08705
uniprot id: F3ZR17
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

679937:BCOP RS08050
gene id: 679937:BCOP_RS08050
uniprot id: F3ZQ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

679937:BCOP RS05700
gene id: 679937:BCOP_RS05700
uniprot id: F3ZU55
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

679937:BCOP RS05345
gene id: 679937:BCOP_RS05345
uniprot id: F3ZT66
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

679937:BCOP RS01605
gene id: 679937:BCOP_RS01605
uniprot id: F3ZQF7
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS07880
gene id: 679937:BCOP_RS07880
uniprot id: F3ZQ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

679937:BCOP RS05200
gene id: 679937:BCOP_RS05200
uniprot id: F3ZUN6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

679937:BCOP RS06485
gene id: 679937:BCOP_RS06485
uniprot id: F3ZNB4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

679937:BCOP RS10350
gene id: 679937:BCOP_RS10350
uniprot id: F3ZSW2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

679937:BCOP RS02635
gene id: 679937:BCOP_RS02635
uniprot id: F3ZRK6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

679937:BCOP RS11435
gene id: 679937:BCOP_RS11435
uniprot id: F3ZUF8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

679937:BCOP RS07550
gene id: 679937:BCOP_RS07550
uniprot id: F3ZPR9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS06940
gene id: 679937:BCOP_RS06940
uniprot id: F3ZNW3
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS11190
gene id: 679937:BCOP_RS11190
uniprot id: F3ZTX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

679937:BCOP RS11420
gene id: 679937:BCOP_RS11420
uniprot id: F3ZUF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

679937:BCOP RS03940
gene id: 679937:BCOP_RS03940
uniprot id: F3ZT10
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

679937:BCOP RS10650
gene id: 679937:BCOP_RS10650
uniprot id: F3ZT94
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

679937:BCOP RS05460
gene id: 679937:BCOP_RS05460
uniprot id: F3ZTM1
names: Similarity
messages: Belongs to the peptidase M16 family.

679937:BCOP RS04760
gene id: 679937:BCOP_RS04760
uniprot id: F3ZU21
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

679937:BCOP RS03470
gene id: 679937:BCOP_RS03470
uniprot id: F3ZSF1
names: Subcellular Location Annotation
messages: Cytoplasm

679937:BCOP RS04835
gene id: 679937:BCOP_RS04835
uniprot id: F3ZU34
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

679937:BCOP RS03155
gene id: 679937:BCOP_RS03155
uniprot id: F3ZS90
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

679937:BCOP RS00220
gene id: 679937:BCOP_RS00220
uniprot id: F3ZNS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

679937:BCOP RS00270
gene id: 679937:BCOP_RS00270
uniprot id: F3ZP48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

679937:BCOP RS06020
gene id: 679937:BCOP_RS06020
uniprot id: F3ZUB8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

679937:BCOP RS10645
gene id: 679937:BCOP_RS10645
uniprot id: F3ZT93
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Fimbrium
messages: Membrane

679937:BCOP RS05695
gene id: 679937:BCOP_RS05695
uniprot id: F3ZU54
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS05965
gene id: 679937:BCOP_RS05965
uniprot id: F3ZUA7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

679937:BCOP RS12045
gene id: 679937:BCOP_RS12045
uniprot id: F3ZNH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

679937:BCOP RS02360
gene id: 679937:BCOP_RS02360
uniprot id: F3ZR87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

679937:BCOP RS02655
gene id: 679937:BCOP_RS02655
uniprot id: F3ZRL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

679937:BCOP RS01035
gene id: 679937:BCOP_RS01035
uniprot id: F3ZPY0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

679937:BCOP RS12315
gene id: 679937:BCOP_RS12315
uniprot id: F3ZNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

679937:BCOP RS05010
gene id: 679937:BCOP_RS05010
uniprot id: F3ZUJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS00255
gene id: 679937:BCOP_RS00255
uniprot id: F3ZP45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

679937:BCOP RS05600
gene id: 679937:BCOP_RS05600
uniprot id: F3ZTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

679937:BCOP RS08945
gene id: 679937:BCOP_RS08945
uniprot id: F3ZRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

679937:BCOP RS00740
gene id: 679937:BCOP_RS00740
uniprot id: F3ZPK7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

679937:BCOP RS01470
gene id: 679937:BCOP_RS01470
uniprot id: F3ZQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

679937:BCOP RS04600
gene id: 679937:BCOP_RS04600
uniprot id: F3ZTZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

679937:BCOP RS11020
gene id: 679937:BCOP_RS11020
uniprot id: F3ZTU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

679937:BCOP RS04655
gene id: 679937:BCOP_RS04655
uniprot id: F3ZU01
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

679937:BCOP RS01125
gene id: 679937:BCOP_RS01125
uniprot id: F3ZPZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

679937:BCOP RS03465
gene id: 679937:BCOP_RS03465
uniprot id: F3ZSF0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

679937:BCOP RS06560
gene id: 679937:BCOP_RS06560
uniprot id: F3ZNC8
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS12455
gene id: 679937:BCOP_RS12455
uniprot id: F3ZP20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

679937:BCOP RS06860
gene id: 679937:BCOP_RS06860
uniprot id: F3ZNU7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

679937:BCOP RS07970
gene id: 679937:BCOP_RS07970
uniprot id: F3ZQ73
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

679937:BCOP RS04855
gene id: 679937:BCOP_RS04855
uniprot id: F3ZU38
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

679937:BCOP RS04960
gene id: 679937:BCOP_RS04960
uniprot id: F3ZU51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

679937:BCOP RS05415
gene id: 679937:BCOP_RS05415
uniprot id: F3ZTL2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

679937:BCOP RS08040
gene id: 679937:BCOP_RS08040
uniprot id: F3ZQ86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

679937:BCOP RS09755
gene id: 679937:BCOP_RS09755
uniprot id: F3ZS72
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

679937:BCOP RS06155
gene id: 679937:BCOP_RS06155
uniprot id: F3ZUT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

679937:BCOP RS05300
gene id: 679937:BCOP_RS05300
uniprot id: F3ZUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

679937:BCOP RS11550
gene id: 679937:BCOP_RS11550
uniprot id: F3ZUH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

679937:BCOP RS01560
gene id: 679937:BCOP_RS01560
uniprot id: F3ZQE8
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS07375
gene id: 679937:BCOP_RS07375
uniprot id: F3ZPG6
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS11115
gene id: 679937:BCOP_RS11115
uniprot id: F3ZTW1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

679937:BCOP RS11030
gene id: 679937:BCOP_RS11030
uniprot id: F3ZTU7
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

679937:BCOP RS03640
gene id: 679937:BCOP_RS03640
uniprot id: F3ZSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

679937:BCOP RS00580
gene id: 679937:BCOP_RS00580
uniprot id: F3ZPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

679937:BCOP RS01845
gene id: 679937:BCOP_RS01845
uniprot id: F3ZQS4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

679937:BCOP RS04660
gene id: 679937:BCOP_RS04660
uniprot id: F3ZU02
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS11175
gene id: 679937:BCOP_RS11175
uniprot id: F3ZTX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

679937:BCOP RS00910
gene id: 679937:BCOP_RS00910
uniprot id: F3ZPN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS11990
gene id: 679937:BCOP_RS11990
uniprot id: F3ZNG5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

679937:BCOP RS05355
gene id: 679937:BCOP_RS05355
uniprot id: F3ZTK0
names: Similarity
messages: Belongs to the DEAD box helicase family.

679937:BCOP RS12095
gene id: 679937:BCOP_RS12095
uniprot id: F3ZNI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

679937:BCOP RS06555
gene id: 679937:BCOP_RS06555
uniprot id: F3ZNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS07255
gene id: 679937:BCOP_RS07255
uniprot id: F3ZPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

679937:BCOP RS02510
gene id: 679937:BCOP_RS02510
uniprot id: F3ZRI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

679937:BCOP RS00810
gene id: 679937:BCOP_RS00810
uniprot id: F3ZPM1
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS03815
gene id: 679937:BCOP_RS03815
uniprot id: F3ZSS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

679937:BCOP RS06890
gene id: 679937:BCOP_RS06890
uniprot id: F3ZNV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

679937:BCOP RS01130
gene id: 679937:BCOP_RS01130
uniprot id: F3ZQ00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

679937:BCOP RS00235
gene id: 679937:BCOP_RS00235
uniprot id: F3ZP41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS05105
gene id: 679937:BCOP_RS05105
uniprot id: F3ZUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

679937:BCOP RS09365
gene id: 679937:BCOP_RS09365
uniprot id: F3ZRT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

679937:BCOP RS03010
gene id: 679937:BCOP_RS03010
uniprot id: F3ZRZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

679937:BCOP RS03095
gene id: 679937:BCOP_RS03095
uniprot id: F3ZS14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

679937:BCOP RS09155
gene id: 679937:BCOP_RS09155
uniprot id: F3ZRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

679937:BCOP RS04305
gene id: 679937:BCOP_RS04305
uniprot id: F3ZTF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

679937:BCOP RS00100
gene id: 679937:BCOP_RS00100
uniprot id: F3ZNQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

679937:BCOP RS09185
gene id: 679937:BCOP_RS09185
uniprot id: F3ZRP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRP transporter (TC 2.A.7.5) family.
messages: Cell membrane
messages: Membrane

679937:BCOP RS11090
gene id: 679937:BCOP_RS11090
uniprot id: F3ZTV6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

679937:BCOP RS01085
gene id: 679937:BCOP_RS01085
uniprot id: F3ZPZ0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

679937:BCOP RS07395
gene id: 679937:BCOP_RS07395
uniprot id: F3ZPH0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

679937:BCOP RS02545
gene id: 679937:BCOP_RS02545
uniprot id: F3ZRJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

679937:BCOP RS03020
gene id: 679937:BCOP_RS03020
uniprot id: F3ZRZ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

679937:BCOP RS06765
gene id: 679937:BCOP_RS06765
uniprot id: F3ZNT0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

679937:BCOP RS09190
gene id: 679937:BCOP_RS09190
uniprot id: F3ZRP6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

679937:BCOP RS11260
gene id: 679937:BCOP_RS11260
uniprot id: F3ZUC5
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

679937:BCOP RS00350
gene id: 679937:BCOP_RS00350
uniprot id: F3ZP63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

679937:BCOP RS01025
gene id: 679937:BCOP_RS01025
uniprot id: F3ZPX8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

679937:BCOP RS00425
gene id: 679937:BCOP_RS00425
uniprot id: F3ZP77
names: Similarity
messages: Belongs to the UPF0597 family.

679937:BCOP RS02530
gene id: 679937:BCOP_RS02530
uniprot id: F3ZRI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

679937:BCOP RS11195
gene id: 679937:BCOP_RS11195
uniprot id: F3ZTX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

679937:BCOP RS07770
gene id: 679937:BCOP_RS07770
uniprot id: F3ZPW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS07810
gene id: 679937:BCOP_RS07810
uniprot id: F3ZQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

679937:BCOP RS05115
gene id: 679937:BCOP_RS05115
uniprot id: F3ZUL9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS12240
gene id: 679937:BCOP_RS12240
uniprot id: F3ZNL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

679937:BCOP RS04055
gene id: 679937:BCOP_RS04055
uniprot id: F3ZT33
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

679937:BCOP RS02265
gene id: 679937:BCOP_RS02265
uniprot id: F3ZR72
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

679937:BCOP RS11795
gene id: 679937:BCOP_RS11795
uniprot id: F3ZV12
names: Similarity
messages: Belongs to the FBPase class 3 family.

679937:BCOP RS06400
gene id: 679937:BCOP_RS06400
uniprot id: F3ZUX8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

679937:BCOP RS06000
gene id: 679937:BCOP_RS06000
uniprot id: F3ZUB4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS10565
gene id: 679937:BCOP_RS10565
uniprot id: F3ZT77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

679937:BCOP RS03265
gene id: 679937:BCOP_RS03265
uniprot id: F3ZSB1
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS02905
gene id: 679937:BCOP_RS02905
uniprot id: F3ZRX5
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS06280
gene id: 679937:BCOP_RS06280
uniprot id: F3ZUV6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

679937:BCOP RS09105
gene id: 679937:BCOP_RS09105
uniprot id: F3ZRG1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS11445
gene id: 679937:BCOP_RS11445
uniprot id: F3ZUG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

679937:BCOP RS00995
gene id: 679937:BCOP_RS00995
uniprot id: F3ZPX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS00360
gene id: 679937:BCOP_RS00360
uniprot id: F3ZP65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

679937:BCOP RS03090
gene id: 679937:BCOP_RS03090
uniprot id: F3ZS13
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

679937:BCOP RS07240
gene id: 679937:BCOP_RS07240
uniprot id: F3ZPD9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

679937:BCOP RS00035
gene id: 679937:BCOP_RS00035
uniprot id: F3ZNN8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

679937:BCOP RS06335
gene id: 679937:BCOP_RS06335
uniprot id: F3ZUW7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS05980
gene id: 679937:BCOP_RS05980
uniprot id: F3ZUB0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

679937:BCOP RS01770
gene id: 679937:BCOP_RS01770
uniprot id: F3ZQQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

679937:BCOP RS11810
gene id: 679937:BCOP_RS11810
uniprot id: F3ZV14
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

679937:BCOP RS00765
gene id: 679937:BCOP_RS00765
uniprot id: F3ZPL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS02310
gene id: 679937:BCOP_RS02310
uniprot id: F3ZR78
names: Similarity
messages: Belongs to the peptidase S41A family.

679937:BCOP RS11230
gene id: 679937:BCOP_RS11230
uniprot id: F3ZTY5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

679937:BCOP RS10440
gene id: 679937:BCOP_RS10440
uniprot id: F3ZSY0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS01390
gene id: 679937:BCOP_RS01390
uniprot id: F3ZQB4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

679937:BCOP RS01150
gene id: 679937:BCOP_RS01150
uniprot id: F3ZQ04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

679937:BCOP RS10480
gene id: 679937:BCOP_RS10480
uniprot id: F3ZSY8
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS12500
gene id: 679937:BCOP_RS12500
uniprot id: F3ZP29
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS06285
gene id: 679937:BCOP_RS06285
uniprot id: F3ZUV7
names: Similarity
messages: Belongs to the CobH/CbiC family.

679937:BCOP RS05835
gene id: 679937:BCOP_RS05835
uniprot id: F3ZU81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

679937:BCOP RS07560
gene id: 679937:BCOP_RS07560
uniprot id: F3ZPS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

679937:BCOP RS01235
gene id: 679937:BCOP_RS01235
uniprot id: F3ZQ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

679937:BCOP RS01160
gene id: 679937:BCOP_RS01160
uniprot id: F3ZQ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

679937:BCOP RS04665
gene id: 679937:BCOP_RS04665
uniprot id: F3ZU03
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS08805
gene id: 679937:BCOP_RS08805
uniprot id: F3ZRA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

679937:BCOP RS01440
gene id: 679937:BCOP_RS01440
uniprot id: F3ZQC3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

679937:BCOP RS06380
gene id: 679937:BCOP_RS06380
uniprot id: F3ZUX4
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS11730
gene id: 679937:BCOP_RS11730
uniprot id: F3ZV00
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

679937:BCOP RS01700
gene id: 679937:BCOP_RS01700
uniprot id: F3ZQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

679937:BCOP RS00805
gene id: 679937:BCOP_RS00805
uniprot id: F3ZPM0
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS05595
gene id: 679937:BCOP_RS05595
uniprot id: F3ZTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS09120
gene id: 679937:BCOP_RS09120
uniprot id: F3ZRN3
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS08980
gene id: 679937:BCOP_RS08980
uniprot id: F3ZRD7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS10375
gene id: 679937:BCOP_RS10375
uniprot id: F3ZSW7
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS02465
gene id: 679937:BCOP_RS02465
uniprot id: F3ZRH6
names: Similarity
messages: Belongs to the SufE family.

679937:BCOP RS04220
gene id: 679937:BCOP_RS04220
uniprot id: F3ZTD5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS01625
gene id: 679937:BCOP_RS01625
uniprot id: F3ZQG1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

679937:BCOP RS02170
gene id: 679937:BCOP_RS02170
uniprot id: F3ZR54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

679937:BCOP RS07245
gene id: 679937:BCOP_RS07245
uniprot id: F3ZPE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

679937:BCOP RS01100
gene id: 679937:BCOP_RS01100
uniprot id: F3ZPZ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

679937:BCOP RS05275
gene id: 679937:BCOP_RS05275
uniprot id: F3ZUQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

679937:BCOP RS08780
gene id: 679937:BCOP_RS08780
uniprot id: F3ZR98
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS05875
gene id: 679937:BCOP_RS05875
uniprot id: F3ZU89
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

679937:BCOP RS07630
gene id: 679937:BCOP_RS07630
uniprot id: F3ZPT5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

679937:BCOP RS03440
gene id: 679937:BCOP_RS03440
uniprot id: F3ZSE5
names: Similarity
messages: Belongs to the UPF0102 family.

679937:BCOP RS02105
gene id: 679937:BCOP_RS02105
uniprot id: F3ZR41
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

679937:BCOP RS08405
gene id: 679937:BCOP_RS08405
uniprot id: F3ZQM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS11330
gene id: 679937:BCOP_RS11330
uniprot id: F3ZUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

679937:BCOP RS11755
gene id: 679937:BCOP_RS11755
uniprot id: F3ZV05
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

679937:BCOP RS10600
gene id: 679937:BCOP_RS10600
uniprot id: F3ZT84
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS11800
gene id: 679937:BCOP_RS11800
uniprot id: F3ZV13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

679937:BCOP RS01475
gene id: 679937:BCOP_RS01475
uniprot id: F3ZQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

679937:BCOP RS03295
gene id: 679937:BCOP_RS03295
uniprot id: F3ZSB7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

679937:BCOP RS05140
gene id: 679937:BCOP_RS05140
uniprot id: F3ZUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

679937:BCOP RS01955
gene id: 679937:BCOP_RS01955
uniprot id: F3ZQU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS11505
gene id: 679937:BCOP_RS11505
uniprot id: F3ZUH2
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS01340
gene id: 679937:BCOP_RS01340
uniprot id: F3ZQA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS02140
gene id: 679937:BCOP_RS02140
uniprot id: F3ZR48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

679937:BCOP RS01860
gene id: 679937:BCOP_RS01860
uniprot id: F3ZQS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

679937:BCOP RS03190
gene id: 679937:BCOP_RS03190
uniprot id: F3ZS96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

679937:BCOP RS02480
gene id: 679937:BCOP_RS02480
uniprot id: F3ZRH9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

679937:BCOP RS02490
gene id: 679937:BCOP_RS02490
uniprot id: F3ZRI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

679937:BCOP RS00840
gene id: 679937:BCOP_RS00840
uniprot id: F3ZPM6
names: Similarity
messages: Belongs to the XseB family.

679937:BCOP RS02645
gene id: 679937:BCOP_RS02645
uniprot id: F3ZRK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

679937:BCOP RS04910
gene id: 679937:BCOP_RS04910
uniprot id: F3ZU41
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

679937:BCOP RS04620
gene id: 679937:BCOP_RS04620
uniprot id: F3ZTZ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

679937:BCOP RS06250
gene id: 679937:BCOP_RS06250
uniprot id: F3ZUV0
names: Similarity
messages: Belongs to the CobT family.

679937:BCOP RS01370
gene id: 679937:BCOP_RS01370
uniprot id: F3ZQB2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

679937:BCOP RS07645
gene id: 679937:BCOP_RS07645
uniprot id: F3ZPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

679937:BCOP RS09200
gene id: 679937:BCOP_RS09200
uniprot id: F3ZRP8
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS00065
gene id: 679937:BCOP_RS00065
uniprot id: F3ZNP4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

679937:BCOP RS01335
gene id: 679937:BCOP_RS01335
uniprot id: F3ZQA5
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS07775
gene id: 679937:BCOP_RS07775
uniprot id: F3ZPW6
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS06200
gene id: 679937:BCOP_RS06200
uniprot id: F3ZUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

679937:BCOP RS01970
gene id: 679937:BCOP_RS01970
uniprot id: F3ZQU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

679937:BCOP RS11265
gene id: 679937:BCOP_RS11265
uniprot id: F3ZUC6
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

679937:BCOP RS00915
gene id: 679937:BCOP_RS00915
uniprot id: F3ZPP0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

679937:BCOP RS00105
gene id: 679937:BCOP_RS00105
uniprot id: F3ZNQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

679937:BCOP RS03060
gene id: 679937:BCOP_RS03060
uniprot id: F3ZS07
names: Similarity
messages: Belongs to the Skp family.

679937:BCOP RS01805
gene id: 679937:BCOP_RS01805
uniprot id: F3ZQR6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

679937:BCOP RS01760
gene id: 679937:BCOP_RS01760
uniprot id: F3ZQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

679937:BCOP RS09265
gene id: 679937:BCOP_RS09265
uniprot id: F3ZRQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

679937:BCOP RS06405
gene id: 679937:BCOP_RS06405
uniprot id: F3ZNA0
names: Similarity
messages: Belongs to the pirin family.

679937:BCOP RS12495
gene id: 679937:BCOP_RS12495
uniprot id: F3ZP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

679937:BCOP RS05280
gene id: 679937:BCOP_RS05280
uniprot id: F3ZUQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

679937:BCOP RS08500
gene id: 679937:BCOP_RS08500
uniprot id: F3ZQX1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

679937:BCOP RS06215
gene id: 679937:BCOP_RS06215
uniprot id: F3ZUU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.

679937:BCOP RS11185
gene id: 679937:BCOP_RS11185
uniprot id: F3ZTX6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

679937:BCOP RS03690
gene id: 679937:BCOP_RS03690
uniprot id: F3ZSQ5
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

679937:BCOP RS11860
gene id: 679937:BCOP_RS11860
uniprot id: F3ZV19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

679937:BCOP RS01170
gene id: 679937:BCOP_RS01170
uniprot id: F3ZQ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

679937:BCOP RS10035
gene id: 679937:BCOP_RS10035
uniprot id: F3ZSJ6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

679937:BCOP RS01545
gene id: 679937:BCOP_RS01545
uniprot id: F3ZQE5
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

679937:BCOP RS10570
gene id: 679937:BCOP_RS10570
uniprot id: F3ZT78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

679937:BCOP RS07390
gene id: 679937:BCOP_RS07390
uniprot id: F3ZPG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS01765
gene id: 679937:BCOP_RS01765
uniprot id: F3ZQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS07790
gene id: 679937:BCOP_RS07790
uniprot id: F3ZQ40
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

679937:BCOP RS07595
gene id: 679937:BCOP_RS07595
uniprot id: F3ZPS8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

679937:BCOP RS05825
gene id: 679937:BCOP_RS05825
uniprot id: F3ZU79
names: Similarity
messages: Belongs to the peptidase C1 family.

679937:BCOP RS08845
gene id: 679937:BCOP_RS08845
uniprot id: F3ZRB1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

679937:BCOP RS03515
gene id: 679937:BCOP_RS03515
uniprot id: F3ZSM3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

679937:BCOP RS01585
gene id: 679937:BCOP_RS01585
uniprot id: F3ZQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

679937:BCOP RS04075
gene id: 679937:BCOP_RS04075
uniprot id: F3ZT37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

679937:BCOP RS03215
gene id: 679937:BCOP_RS03215
uniprot id: F3ZSA1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

679937:BCOP RS08535
gene id: 679937:BCOP_RS08535
uniprot id: F3ZQX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

679937:BCOP RS01165
gene id: 679937:BCOP_RS01165
uniprot id: F3ZQ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

679937:BCOP RS04995
gene id: 679937:BCOP_RS04995
uniprot id: F3ZUJ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

679937:BCOP RS09175
gene id: 679937:BCOP_RS09175
uniprot id: F3ZRP3
names: Similarity
messages: Belongs to the peptidase C59 family.

679937:BCOP RS05190
gene id: 679937:BCOP_RS05190
uniprot id: F3ZUN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

679937:BCOP RS06330
gene id: 679937:BCOP_RS06330
uniprot id: F3ZUW6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS12375
gene id: 679937:BCOP_RS12375
uniprot id: F3ZP04
names: Similarity
messages: Belongs to the glutamine synthetase family.

679937:BCOP RS07940
gene id: 679937:BCOP_RS07940
uniprot id: F3ZQ67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

679937:BCOP RS03415
gene id: 679937:BCOP_RS03415
uniprot id: F3ZSE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

679937:BCOP RS02475
gene id: 679937:BCOP_RS02475
uniprot id: F3ZRH8
names: Similarity
messages: Belongs to the peptidase S66 family.

679937:BCOP RS12360
gene id: 679937:BCOP_RS12360
uniprot id: F3ZP01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

679937:BCOP RS05020
gene id: 679937:BCOP_RS05020
uniprot id: F3ZUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

679937:BCOP RS07060
gene id: 679937:BCOP_RS07060
uniprot id: F3ZNY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

679937:BCOP RS01140
gene id: 679937:BCOP_RS01140
uniprot id: F3ZQ02
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

679937:BCOP RS09270
gene id: 679937:BCOP_RS09270
uniprot id: F3ZRR0
names: Similarity
messages: Belongs to the TrpF family.

679937:BCOP RS11695
gene id: 679937:BCOP_RS11695
uniprot id: F3ZUZ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS00635
gene id: 679937:BCOP_RS00635
uniprot id: F3ZPI6
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS09030
gene id: 679937:BCOP_RS09030
uniprot id: F3ZRE6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

679937:BCOP RS02565
gene id: 679937:BCOP_RS02565
uniprot id: F3ZRJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

679937:BCOP RS05565
gene id: 679937:BCOP_RS05565
uniprot id: F3ZTP2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS03425
gene id: 679937:BCOP_RS03425
uniprot id: F3ZSE2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS09350
gene id: 679937:BCOP_RS09350
uniprot id: F3ZRS8
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS05810
gene id: 679937:BCOP_RS05810
uniprot id: F3ZU76
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

679937:BCOP RS04965
gene id: 679937:BCOP_RS04965
uniprot id: F3ZU52
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

679937:BCOP RS09960
gene id: 679937:BCOP_RS09960
uniprot id: F3ZSI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS08550
gene id: 679937:BCOP_RS08550
uniprot id: F3ZQY2
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

679937:BCOP RS09640
gene id: 679937:BCOP_RS09640
uniprot id: F3ZS53
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

679937:BCOP RS05515
gene id: 679937:BCOP_RS05515
uniprot id: F3ZTN2
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS12110
gene id: 679937:BCOP_RS12110
uniprot id: F3ZNJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

679937:BCOP RS12225
gene id: 679937:BCOP_RS12225
uniprot id: F3ZNL1
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS05270
gene id: 679937:BCOP_RS05270
uniprot id: F3ZUP9
names: Similarity
messages: Belongs to the aspartokinase family.

679937:BCOP RS04080
gene id: 679937:BCOP_RS04080
uniprot id: F3ZT38
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

679937:BCOP RS07490
gene id: 679937:BCOP_RS07490
uniprot id: F3ZPQ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

679937:BCOP RS02960
gene id: 679937:BCOP_RS02960
uniprot id: F3ZRY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

679937:BCOP RS02175
gene id: 679937:BCOP_RS02175
uniprot id: F3ZR55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

679937:BCOP RS07350
gene id: 679937:BCOP_RS07350
uniprot id: F3ZPG1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS06260
gene id: 679937:BCOP_RS06260
uniprot id: F3ZUV2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

679937:BCOP RS02165
gene id: 679937:BCOP_RS02165
uniprot id: F3ZR53
names: Similarity
messages: Belongs to the pyruvate kinase family.

679937:BCOP RS04120
gene id: 679937:BCOP_RS04120
uniprot id: F3ZT46
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS07635
gene id: 679937:BCOP_RS07635
uniprot id: F3ZPT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

679937:BCOP RS02365
gene id: 679937:BCOP_RS02365
uniprot id: F3ZR88
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

679937:BCOP RS01640
gene id: 679937:BCOP_RS01640
uniprot id: F3ZQG4
names: Similarity
messages: Belongs to the GARS family.

679937:BCOP RS11665
gene id: 679937:BCOP_RS11665
uniprot id: F3ZUY7
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

679937:BCOP RS00080
gene id: 679937:BCOP_RS00080
uniprot id: F3ZNP7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

679937:BCOP RS04830
gene id: 679937:BCOP_RS04830
uniprot id: F3ZU33
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

679937:BCOP RS06900
gene id: 679937:BCOP_RS06900
uniprot id: F3ZNV5
names: Similarity
messages: Belongs to the YjdM family.

679937:BCOP RS07165
gene id: 679937:BCOP_RS07165
uniprot id: F3ZPC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

679937:BCOP RS02880
gene id: 679937:BCOP_RS02880
uniprot id: F3ZRX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

679937:BCOP RS01465
gene id: 679937:BCOP_RS01465
uniprot id: F3ZQC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

679937:BCOP RS01425
gene id: 679937:BCOP_RS01425
uniprot id: F3ZQC0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

679937:BCOP RS03175
gene id: 679937:BCOP_RS03175
uniprot id: F3ZS94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

679937:BCOP RS07090
gene id: 679937:BCOP_RS07090
uniprot id: F3ZNZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

679937:BCOP RS03670
gene id: 679937:BCOP_RS03670
uniprot id: F3ZSQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

679937:BCOP RS01840
gene id: 679937:BCOP_RS01840
uniprot id: F3ZQS3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

679937:BCOP RS06935
gene id: 679937:BCOP_RS06935
uniprot id: F3ZNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS10355
gene id: 679937:BCOP_RS10355
uniprot id: F3ZSW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

679937:BCOP RS10085
gene id: 679937:BCOP_RS10085
uniprot id: F3ZSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS00095
gene id: 679937:BCOP_RS00095
uniprot id: F3ZNQ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

679937:BCOP RS07470
gene id: 679937:BCOP_RS07470
uniprot id: F3ZPQ3
names: Similarity
messages: Belongs to the peptidase M17 family.

679937:BCOP RS00875
gene id: 679937:BCOP_RS00875
uniprot id: F3ZPN3
names: Similarity
messages: Belongs to the SUI1 family.

679937:BCOP RS03945
gene id: 679937:BCOP_RS03945
uniprot id: F3ZT11
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

679937:BCOP RS03200
gene id: 679937:BCOP_RS03200
uniprot id: F3ZS98
names: Similarity
messages: Belongs to the CvfB family.

679937:BCOP RS09695
gene id: 679937:BCOP_RS09695
uniprot id: F3ZS64
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

679937:BCOP RS09455
gene id: 679937:BCOP_RS09455
uniprot id: F3ZRU9
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

679937:BCOP RS04515
gene id: 679937:BCOP_RS04515
uniprot id: F3ZTJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

679937:BCOP RS00165
gene id: 679937:BCOP_RS00165
uniprot id: F3ZNR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

679937:BCOP RS09440
gene id: 679937:BCOP_RS09440
uniprot id: F3ZRU6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

679937:BCOP RS02750
gene id: 679937:BCOP_RS02750
uniprot id: F3ZRM5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

679937:BCOP RS03885
gene id: 679937:BCOP_RS03885
uniprot id: F3ZSZ9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS04160
gene id: 679937:BCOP_RS04160
uniprot id: F3ZT51
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

679937:BCOP RS11780
gene id: 679937:BCOP_RS11780
uniprot id: F3ZV09
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

679937:BCOP RS07045
gene id: 679937:BCOP_RS07045
uniprot id: F3ZNY3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

679937:BCOP RS00505
gene id: 679937:BCOP_RS00505
uniprot id: F3ZP92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

679937:BCOP RS11930
gene id: 679937:BCOP_RS11930
uniprot id: F3ZV31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

679937:BCOP RS04165
gene id: 679937:BCOP_RS04165
uniprot id: F3ZT52
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

679937:BCOP RS05955
gene id: 679937:BCOP_RS05955
uniprot id: F3ZUA5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

679937:BCOP RS02040
gene id: 679937:BCOP_RS02040
uniprot id: F3ZQW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

679937:BCOP RS00985
gene id: 679937:BCOP_RS00985
uniprot id: F3ZPW9
names: Similarity
messages: Belongs to the UPF0246 family.

679937:BCOP RS09315
gene id: 679937:BCOP_RS09315
uniprot id: F3ZRS1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

679937:BCOP RS05360
gene id: 679937:BCOP_RS05360
uniprot id: F3ZTK1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

679937:BCOP RS06310
gene id: 679937:BCOP_RS06310
uniprot id: F3ZUW2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

679937:BCOP RS07015
gene id: 679937:BCOP_RS07015
uniprot id: F3ZNX8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

679937:BCOP RS04715
gene id: 679937:BCOP_RS04715
uniprot id: F3ZU13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

679937:BCOP RS01240
gene id: 679937:BCOP_RS01240
uniprot id: F3ZQ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

679937:BCOP RS05120
gene id: 679937:BCOP_RS05120
uniprot id: F3ZUM0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

679937:BCOP RS00705
gene id: 679937:BCOP_RS00705
uniprot id: F3ZPK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

679937:BCOP RS04720
gene id: 679937:BCOP_RS04720
uniprot id: F3ZU14
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

679937:BCOP RS00860
gene id: 679937:BCOP_RS00860
uniprot id: F3ZPN0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS04370
gene id: 679937:BCOP_RS04370
uniprot id: F3ZTG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

679937:BCOP RS06415
gene id: 679937:BCOP_RS06415
uniprot id: F3ZNA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

679937:BCOP RS05855
gene id: 679937:BCOP_RS05855
uniprot id: F3ZU85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

679937:BCOP RS04955
gene id: 679937:BCOP_RS04955
uniprot id: F3ZU50
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

679937:BCOP RS05840
gene id: 679937:BCOP_RS05840
uniprot id: F3ZU82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

679937:BCOP RS12215
gene id: 679937:BCOP_RS12215
uniprot id: F3ZNK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

679937:BCOP RS05555
gene id: 679937:BCOP_RS05555
uniprot id: F3ZTP0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS04070
gene id: 679937:BCOP_RS04070
uniprot id: F3ZT36
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

679937:BCOP RS00275
gene id: 679937:BCOP_RS00275
uniprot id: F3ZP49
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

679937:BCOP RS00320
gene id: 679937:BCOP_RS00320
uniprot id: F3ZP58
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

679937:BCOP RS10520
gene id: 679937:BCOP_RS10520
uniprot id: F3ZT69
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

679937:BCOP RS08630
gene id: 679937:BCOP_RS08630
uniprot id: F3ZR01
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

679937:BCOP RS05750
gene id: 679937:BCOP_RS05750
uniprot id: F3ZU65
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

679937:BCOP RS10080
gene id: 679937:BCOP_RS10080
uniprot id: F3ZSK4
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS00555
gene id: 679937:BCOP_RS00555
uniprot id: F3ZPA2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

679937:BCOP RS03600
gene id: 679937:BCOP_RS03600
uniprot id: F3ZSN8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

679937:BCOP RS11570
gene id: 679937:BCOP_RS11570
uniprot id: F3ZUI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

679937:BCOP RS02210
gene id: 679937:BCOP_RS02210
uniprot id: F3ZR61
names: Similarity
messages: Belongs to the Nudix hydrolase family.

679937:BCOP RS00005
gene id: 679937:BCOP_RS00005
uniprot id: F3ZNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

679937:BCOP RS06965
gene id: 679937:BCOP_RS06965
uniprot id: F3ZNW8
names: Subcellular Location Annotation
messages: Cytoplasm

679937:BCOP RS06140
gene id: 679937:BCOP_RS06140
uniprot id: F3ZUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

679937:BCOP RS12355
gene id: 679937:BCOP_RS12355
uniprot id: F3ZP00
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS10370
gene id: 679937:BCOP_RS10370
uniprot id: F3ZSW6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS05895
gene id: 679937:BCOP_RS05895
uniprot id: F3ZU93
names: Similarity
messages: Belongs to the class-I fumarase family.

679937:BCOP RS07945
gene id: 679937:BCOP_RS07945
uniprot id: F3ZQ68
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

679937:BCOP RS12430
gene id: 679937:BCOP_RS12430
uniprot id: F3ZP15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

679937:BCOP RS01710
gene id: 679937:BCOP_RS01710
uniprot id: F3ZQP8
names: Similarity
messages: Belongs to the peptidase M16 family.

679937:BCOP RS01355
gene id: 679937:BCOP_RS01355
uniprot id: F3ZQA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

679937:BCOP RS03410
gene id: 679937:BCOP_RS03410
uniprot id: F3ZSD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

679937:BCOP RS05440
gene id: 679937:BCOP_RS05440
uniprot id: F3ZTL7
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS01730
gene id: 679937:BCOP_RS01730
uniprot id: F3ZQQ2
names: Similarity
messages: Belongs to the DEAD box helicase family.

679937:BCOP RS04615
gene id: 679937:BCOP_RS04615
uniprot id: F3ZTZ3
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

679937:BCOP RS02390
gene id: 679937:BCOP_RS02390
uniprot id: F3ZR93
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

679937:BCOP RS05640
gene id: 679937:BCOP_RS05640
uniprot id: F3ZTQ7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

679937:BCOP RS05250
gene id: 679937:BCOP_RS05250
uniprot id: F3ZUP5
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS01480
gene id: 679937:BCOP_RS01480
uniprot id: F3ZQD1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

679937:BCOP RS00410
gene id: 679937:BCOP_RS00410
uniprot id: F3ZP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

679937:BCOP RS04015
gene id: 679937:BCOP_RS04015
uniprot id: F3ZT25
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

679937:BCOP RS07610
gene id: 679937:BCOP_RS07610
uniprot id: F3ZPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

679937:BCOP RS12410
gene id: 679937:BCOP_RS12410
uniprot id: F3ZP11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

679937:BCOP RS04170
gene id: 679937:BCOP_RS04170
uniprot id: F3ZT53
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

679937:BCOP RS08620
gene id: 679937:BCOP_RS08620
uniprot id: F3ZQZ8
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS03055
gene id: 679937:BCOP_RS03055
uniprot id: F3ZS06
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

679937:BCOP RS07920
gene id: 679937:BCOP_RS07920
uniprot id: F3ZQ64
names: Similarity
messages: Belongs to the heat shock protein 90 family.

679937:BCOP RS02525
gene id: 679937:BCOP_RS02525
uniprot id: F3ZRI8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

679937:BCOP RS12115
gene id: 679937:BCOP_RS12115
uniprot id: F3ZNJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

679937:BCOP RS02410
gene id: 679937:BCOP_RS02410
uniprot id: F3ZRG5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

679937:BCOP RS11110
gene id: 679937:BCOP_RS11110
uniprot id: F3ZTW0
names: Similarity
messages: Belongs to the transketolase family.

679937:BCOP RS06395
gene id: 679937:BCOP_RS06395
uniprot id: F3ZUX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

679937:BCOP RS00395
gene id: 679937:BCOP_RS00395
uniprot id: F3ZP71
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS02580
gene id: 679937:BCOP_RS02580
uniprot id: F3ZRJ9
names: Similarity
messages: Belongs to the peptidase M24B family.

679937:BCOP RS05585
gene id: 679937:BCOP_RS05585
uniprot id: F3ZTP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

679937:BCOP RS01620
gene id: 679937:BCOP_RS01620
uniprot id: F3ZQG0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

679937:BCOP RS03100
gene id: 679937:BCOP_RS03100
uniprot id: F3ZS15
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS02840
gene id: 679937:BCOP_RS02840
uniprot id: F3ZRW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS07925
gene id: 679937:BCOP_RS07925
uniprot id: F3ZQ65
names: Similarity
messages: Belongs to the ClpA/ClpB family.

679937:BCOP RS11360
gene id: 679937:BCOP_RS11360
uniprot id: F3ZUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

679937:BCOP RS03280
gene id: 679937:BCOP_RS03280
uniprot id: F3ZSB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

679937:BCOP RS04850
gene id: 679937:BCOP_RS04850
uniprot id: F3ZU37
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

679937:BCOP RS06825
gene id: 679937:BCOP_RS06825
uniprot id: F3ZNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

679937:BCOP RS07725
gene id: 679937:BCOP_RS07725
uniprot id: F3ZPV6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

679937:BCOP RS03490
gene id: 679937:BCOP_RS03490
uniprot id: F3ZSF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

679937:BCOP RS05950
gene id: 679937:BCOP_RS05950
uniprot id: F3ZUA4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

679937:BCOP RS01880
gene id: 679937:BCOP_RS01880
uniprot id: F3ZQT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

679937:BCOP RS01415
gene id: 679937:BCOP_RS01415
uniprot id: F3ZQB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

679937:BCOP RS05215
gene id: 679937:BCOP_RS05215
uniprot id: F3ZUN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS01000
gene id: 679937:BCOP_RS01000
uniprot id: F3ZPX3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

679937:BCOP RS06270
gene id: 679937:BCOP_RS06270
uniprot id: F3ZUV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

679937:BCOP RS06355
gene id: 679937:BCOP_RS06355
uniprot id: F3ZUX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

679937:BCOP RS04595
gene id: 679937:BCOP_RS04595
uniprot id: F3ZTY9
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

679937:BCOP RS02235
gene id: 679937:BCOP_RS02235
uniprot id: F3ZR66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

679937:BCOP RS01110
gene id: 679937:BCOP_RS01110
uniprot id: F3ZPZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

679937:BCOP RS01960
gene id: 679937:BCOP_RS01960
uniprot id: F3ZQU7
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

679937:BCOP RS12480
gene id: 679937:BCOP_RS12480
uniprot id: F3ZP25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

679937:BCOP RS09360
gene id: 679937:BCOP_RS09360
uniprot id: F3ZRT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

679937:BCOP RS11105
gene id: 679937:BCOP_RS11105
uniprot id: F3ZTV9
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

679937:BCOP RS11515
gene id: 679937:BCOP_RS11515
uniprot id: F3ZUH4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

679937:BCOP RS04450
gene id: 679937:BCOP_RS04450
uniprot id: F3ZTH7
names: Similarity
messages: Belongs to the ArsC family.

679937:BCOP RS02640
gene id: 679937:BCOP_RS02640
uniprot id: F3ZRK7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

679937:BCOP RS00630
gene id: 679937:BCOP_RS00630
uniprot id: F3ZPI5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

679937:BCOP RS01245
gene id: 679937:BCOP_RS01245
uniprot id: F3ZQ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

679937:BCOP RS12395
gene id: 679937:BCOP_RS12395
uniprot id: F3ZP08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

679937:BCOP RS00390
gene id: 679937:BCOP_RS00390
uniprot id: F3ZP70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

679937:BCOP RS01155
gene id: 679937:BCOP_RS01155
uniprot id: F3ZQ05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

679937:BCOP RS01695
gene id: 679937:BCOP_RS01695
uniprot id: F3ZQP5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

679937:BCOP RS03475
gene id: 679937:BCOP_RS03475
uniprot id: F3ZSF2
names: Similarity
messages: Belongs to the thioredoxin family.

679937:BCOP RS03005
gene id: 679937:BCOP_RS03005
uniprot id: F3ZRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

679937:BCOP RS01430
gene id: 679937:BCOP_RS01430
uniprot id: F3ZQC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

679937:BCOP RS04695
gene id: 679937:BCOP_RS04695
uniprot id: F3ZU09
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS07345
gene id: 679937:BCOP_RS07345
uniprot id: F3ZPG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

679937:BCOP RS00375
gene id: 679937:BCOP_RS00375
uniprot id: F3ZP67
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

679937:BCOP RS12280
gene id: 679937:BCOP_RS12280
uniprot id: F3ZNM2
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS03565
gene id: 679937:BCOP_RS03565
uniprot id: F3ZSN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

679937:BCOP RS06895
gene id: 679937:BCOP_RS06895
uniprot id: F3ZNV4
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS12510
gene id: 679937:BCOP_RS12510
uniprot id: F3ZP31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS06720
gene id: 679937:BCOP_RS06720
uniprot id: F3ZNF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

679937:BCOP RS02425
gene id: 679937:BCOP_RS02425
uniprot id: F3ZRG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

679937:BCOP RS05000
gene id: 679937:BCOP_RS05000
uniprot id: F3ZUJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

679937:BCOP RS02110
gene id: 679937:BCOP_RS02110
uniprot id: F3ZR42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

679937:BCOP RS12300
gene id: 679937:BCOP_RS12300
uniprot id: F3ZNM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS06690
gene id: 679937:BCOP_RS06690
uniprot id: F3ZNF2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

679937:BCOP RS04650
gene id: 679937:BCOP_RS04650
uniprot id: F3ZU00
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

679937:BCOP RS01795
gene id: 679937:BCOP_RS01795
uniprot id: F3ZQR4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

679937:BCOP RS08890
gene id: 679937:BCOP_RS08890
uniprot id: F3ZRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS03955
gene id: 679937:BCOP_RS03955
uniprot id: F3ZT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

679937:BCOP RS04500
gene id: 679937:BCOP_RS04500
uniprot id: F3ZTI7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS08245
gene id: 679937:BCOP_RS08245
uniprot id: F3ZQJ8
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS07605
gene id: 679937:BCOP_RS07605
uniprot id: F3ZPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

679937:BCOP RS10525
gene id: 679937:BCOP_RS10525
uniprot id: F3ZT70
names: Similarity
messages: Belongs to the Nudix hydrolase family.

679937:BCOP RS04405
gene id: 679937:BCOP_RS04405
uniprot id: F3ZTG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

679937:BCOP RS00770
gene id: 679937:BCOP_RS00770
uniprot id: F3ZPL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS07190
gene id: 679937:BCOP_RS07190
uniprot id: F3ZPC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

679937:BCOP RS10045
gene id: 679937:BCOP_RS10045
uniprot id: F3ZSJ7
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS03700
gene id: 679937:BCOP_RS03700
uniprot id: F3ZSQ7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

679937:BCOP RS07010
gene id: 679937:BCOP_RS07010
uniprot id: F3ZNX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

679937:BCOP RS04585
gene id: 679937:BCOP_RS04585
uniprot id: F3ZTY8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

679937:BCOP RS03330
gene id: 679937:BCOP_RS03330
uniprot id: F3ZSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS12485
gene id: 679937:BCOP_RS12485
uniprot id: F3ZP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

679937:BCOP RS01205
gene id: 679937:BCOP_RS01205
uniprot id: F3ZQ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

679937:BCOP RS11705
gene id: 679937:BCOP_RS11705
uniprot id: F3ZUZ5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS11405
gene id: 679937:BCOP_RS11405
uniprot id: F3ZUF3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

679937:BCOP RS11040
gene id: 679937:BCOP_RS11040
uniprot id: F3ZTU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

679937:BCOP RS04175
gene id: 679937:BCOP_RS04175
uniprot id: F3ZT54
names: Similarity
messages: Belongs to the peptidase S49 family.

679937:BCOP RS11450
gene id: 679937:BCOP_RS11450
uniprot id: F3ZUG1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

679937:BCOP RS03400
gene id: 679937:BCOP_RS03400
uniprot id: F3ZSD7
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS08415
gene id: 679937:BCOP_RS08415
uniprot id: F3ZQN0
names: Similarity
messages: Belongs to the group II decarboxylase family.

679937:BCOP RS00695
gene id: 679937:BCOP_RS00695
uniprot id: F3ZPJ8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

679937:BCOP RS00870
gene id: 679937:BCOP_RS00870
uniprot id: F3ZPN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

679937:BCOP RS04340
gene id: 679937:BCOP_RS04340
uniprot id: F3ZTF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

679937:BCOP RS04065
gene id: 679937:BCOP_RS04065
uniprot id: F3ZT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

679937:BCOP RS01510
gene id: 679937:BCOP_RS01510
uniprot id: F3ZQD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

679937:BCOP RS06050
gene id: 679937:BCOP_RS06050
uniprot id: F3ZUR0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

679937:BCOP RS09935
gene id: 679937:BCOP_RS09935
uniprot id: F3ZSH3
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

679937:BCOP RS09525
gene id: 679937:BCOP_RS09525
uniprot id: F3ZS33
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

679937:BCOP RS11785
gene id: 679937:BCOP_RS11785
uniprot id: F3ZV10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

679937:BCOP RS01325
gene id: 679937:BCOP_RS01325
uniprot id: F3ZQA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

679937:BCOP RS05505
gene id: 679937:BCOP_RS05505
uniprot id: F3ZTN0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

679937:BCOP RS03505
gene id: 679937:BCOP_RS03505
uniprot id: F3ZSM1
names: Similarity
messages: Belongs to the EPSP synthase family.

679937:BCOP RS08835
gene id: 679937:BCOP_RS08835
uniprot id: F3ZRA9
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS00880
gene id: 679937:BCOP_RS00880
uniprot id: F3ZPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

679937:BCOP RS07445
gene id: 679937:BCOP_RS07445
uniprot id: F3ZPH8
names: Similarity
messages: Belongs to the DEAD box helicase family.

679937:BCOP RS03950
gene id: 679937:BCOP_RS03950
uniprot id: F3ZT12
names: Similarity
messages: Belongs to the AIR synthase family.

679937:BCOP RS07005
gene id: 679937:BCOP_RS07005
uniprot id: F3ZNX5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

679937:BCOP RS07705
gene id: 679937:BCOP_RS07705
uniprot id: F3ZPV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS01105
gene id: 679937:BCOP_RS01105
uniprot id: F3ZPZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

679937:BCOP RS06710
gene id: 679937:BCOP_RS06710
uniprot id: F3ZNF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

679937:BCOP RS00960
gene id: 679937:BCOP_RS00960
uniprot id: F3ZPP9
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS05920
gene id: 679937:BCOP_RS05920
uniprot id: F3ZU98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

679937:BCOP RS05240
gene id: 679937:BCOP_RS05240
uniprot id: F3ZUP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

679937:BCOP RS05615
gene id: 679937:BCOP_RS05615
uniprot id: F3ZTQ2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

679937:BCOP RS01030
gene id: 679937:BCOP_RS01030
uniprot id: F3ZPX9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

679937:BCOP RS00290
gene id: 679937:BCOP_RS00290
uniprot id: F3ZP52
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

679937:BCOP RS00400
gene id: 679937:BCOP_RS00400
uniprot id: F3ZP72
names: Similarity
messages: Belongs to the citrate synthase family.

679937:BCOP RS07785
gene id: 679937:BCOP_RS07785
uniprot id: F3ZQ39
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

679937:BCOP RS03910
gene id: 679937:BCOP_RS03910
uniprot id: F3ZT04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

679937:BCOP RS01890
gene id: 679937:BCOP_RS01890
uniprot id: F3ZQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS10605
gene id: 679937:BCOP_RS10605
uniprot id: F3ZT85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

679937:BCOP RS07340
gene id: 679937:BCOP_RS07340
uniprot id: F3ZPF9
names: Similarity
messages: Belongs to the isochorismate synthase family.

679937:BCOP RS03345
gene id: 679937:BCOP_RS03345
uniprot id: F3ZSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

679937:BCOP RS02540
gene id: 679937:BCOP_RS02540
uniprot id: F3ZRJ1
names: Similarity
messages: Belongs to the sigma-54 factor family.

679937:BCOP RS00295
gene id: 679937:BCOP_RS00295
uniprot id: F3ZP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

679937:BCOP RS08055
gene id: 679937:BCOP_RS08055
uniprot id: F3ZQ89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

679937:BCOP RS03830
gene id: 679937:BCOP_RS03830
uniprot id: F3ZSS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS08830
gene id: 679937:BCOP_RS08830
uniprot id: F3ZRA8
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS09290
gene id: 679937:BCOP_RS09290
uniprot id: F3ZRR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

679937:BCOP RS12475
gene id: 679937:BCOP_RS12475
uniprot id: F3ZP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

679937:BCOP RS09320
gene id: 679937:BCOP_RS09320
uniprot id: F3ZRS2
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS00195
gene id: 679937:BCOP_RS00195
uniprot id: F3ZNS1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

679937:BCOP RS03835
gene id: 679937:BCOP_RS03835
uniprot id: F3ZSS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

679937:BCOP RS01810
gene id: 679937:BCOP_RS01810
uniprot id: F3ZQR7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

679937:BCOP RS00550
gene id: 679937:BCOP_RS00550
uniprot id: F3ZPA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

679937:BCOP RS00825
gene id: 679937:BCOP_RS00825
uniprot id: F3ZPM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

679937:BCOP RS12220
gene id: 679937:BCOP_RS12220
uniprot id: F3ZNL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

679937:BCOP RS01495
gene id: 679937:BCOP_RS01495
uniprot id: F3ZQD4
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS11630
gene id: 679937:BCOP_RS11630
uniprot id: F3ZUX9
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

679937:BCOP RS07500
gene id: 679937:BCOP_RS07500
uniprot id: F3ZPQ9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

679937:BCOP RS09995
gene id: 679937:BCOP_RS09995
uniprot id: F3ZSI7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

679937:BCOP RS11650
gene id: 679937:BCOP_RS11650
uniprot id: F3ZUY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

679937:BCOP RS00920
gene id: 679937:BCOP_RS00920
uniprot id: F3ZPP1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

679937:BCOP RS04235
gene id: 679937:BCOP_RS04235
uniprot id: F3ZTD8
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS02085
gene id: 679937:BCOP_RS02085
uniprot id: F3ZR37
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

679937:BCOP RS01790
gene id: 679937:BCOP_RS01790
uniprot id: F3ZQR3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

679937:BCOP RS03065
gene id: 679937:BCOP_RS03065
uniprot id: F3ZS08
names: Similarity
messages: Belongs to the Skp family.

679937:BCOP RS04010
gene id: 679937:BCOP_RS04010
uniprot id: F3ZT24
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS05830
gene id: 679937:BCOP_RS05830
uniprot id: F3ZU80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

679937:BCOP RS00125
gene id: 679937:BCOP_RS00125
uniprot id: F3ZNQ7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

679937:BCOP RS07400
gene id: 679937:BCOP_RS07400
uniprot id: F3ZPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

679937:BCOP RS04640
gene id: 679937:BCOP_RS04640
uniprot id: F3ZTZ8
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS05470
gene id: 679937:BCOP_RS05470
uniprot id: F3ZTM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

679937:BCOP RS02100
gene id: 679937:BCOP_RS02100
uniprot id: F3ZR40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS00755
gene id: 679937:BCOP_RS00755
uniprot id: F3ZPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

679937:BCOP RS05435
gene id: 679937:BCOP_RS05435
uniprot id: F3ZTL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

679937:BCOP RS04605
gene id: 679937:BCOP_RS04605
uniprot id: F3ZTZ1
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS06185
gene id: 679937:BCOP_RS06185
uniprot id: F3ZUT7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

679937:BCOP RS05800
gene id: 679937:BCOP_RS05800
uniprot id: F3ZU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

679937:BCOP RS03450
gene id: 679937:BCOP_RS03450
uniprot id: F3ZSE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

679937:BCOP RS01120
gene id: 679937:BCOP_RS01120
uniprot id: F3ZPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

679937:BCOP RS07220
gene id: 679937:BCOP_RS07220
uniprot id: F3ZPD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS00730
gene id: 679937:BCOP_RS00730
uniprot id: F3ZPK5
names: Similarity
messages: Belongs to the NDK family.

679937:BCOP RS00990
gene id: 679937:BCOP_RS00990
uniprot id: F3ZPX0
names: Similarity
messages: Belongs to the CarB family.

679937:BCOP RS06275
gene id: 679937:BCOP_RS06275
uniprot id: F3ZUV5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

679937:BCOP RS04970
gene id: 679937:BCOP_RS04970
uniprot id: F3ZUJ0
names: Similarity
messages: Belongs to the asparaginase 1 family.

679937:BCOP RS04335
gene id: 679937:BCOP_RS04335
uniprot id: F3ZTF5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

679937:BCOP RS04975
gene id: 679937:BCOP_RS04975
uniprot id: F3ZUJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

679937:BCOP RS01095
gene id: 679937:BCOP_RS01095
uniprot id: F3ZPZ2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

679937:BCOP RS00070
gene id: 679937:BCOP_RS00070
uniprot id: F3ZNP5
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

679937:BCOP RS01330
gene id: 679937:BCOP_RS01330
uniprot id: F3ZQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

679937:BCOP RS08455
gene id: 679937:BCOP_RS08455
uniprot id: F3ZQN9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

679937:BCOP RS02335
gene id: 679937:BCOP_RS02335
uniprot id: F3ZR82
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

679937:BCOP RS05870
gene id: 679937:BCOP_RS05870
uniprot id: F3ZU88
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS12385
gene id: 679937:BCOP_RS12385
uniprot id: F3ZP06
names: Similarity
messages: Belongs to the type IA topoisomerase family.

679937:BCOP RS12440
gene id: 679937:BCOP_RS12440
uniprot id: F3ZP17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

679937:BCOP RS02890
gene id: 679937:BCOP_RS02890
uniprot id: F3ZRX2
names: Similarity
messages: Belongs to the peptidase U62 family.

679937:BCOP RS08910
gene id: 679937:BCOP_RS08910
uniprot id: F3ZRC3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

679937:BCOP RS04310
gene id: 679937:BCOP_RS04310
uniprot id: F3ZTF3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

679937:BCOP RS01595
gene id: 679937:BCOP_RS01595
uniprot id: F3ZQF5
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS04285
gene id: 679937:BCOP_RS04285
uniprot id: F3ZTE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

679937:BCOP RS04400
gene id: 679937:BCOP_RS04400
uniprot id: F3ZTG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

679937:BCOP RS12550
gene id: 679937:BCOP_RS12550
uniprot id: F3ZP38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS00225
gene id: 679937:BCOP_RS00225
uniprot id: F3ZNS7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS00830
gene id: 679937:BCOP_RS00830
uniprot id: F3ZPM4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS11725
gene id: 679937:BCOP_RS11725
uniprot id: F3ZUZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS07385
gene id: 679937:BCOP_RS07385
uniprot id: F3ZPG8
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS05930
gene id: 679937:BCOP_RS05930
uniprot id: F3ZUA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

679937:BCOP RS03370
gene id: 679937:BCOP_RS03370
uniprot id: F3ZSD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

679937:BCOP RS02225
gene id: 679937:BCOP_RS02225
uniprot id: F3ZR64
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

679937:BCOP RS01940
gene id: 679937:BCOP_RS01940
uniprot id: F3ZQU3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

679937:BCOP RS00380
gene id: 679937:BCOP_RS00380
uniprot id: F3ZP68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

679937:BCOP RS11720
gene id: 679937:BCOP_RS11720
uniprot id: F3ZUZ8
names: Similarity
messages: Belongs to the threonine synthase family.

679937:BCOP RS00895
gene id: 679937:BCOP_RS00895
uniprot id: F3ZPN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

679937:BCOP RS10005
gene id: 679937:BCOP_RS10005
uniprot id: F3ZSI9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

679937:BCOP RS06875
gene id: 679937:BCOP_RS06875
uniprot id: F3ZNV0
names: Similarity
messages: Belongs to the DprA/Smf family.

679937:BCOP RS01230
gene id: 679937:BCOP_RS01230
uniprot id: F3ZQ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

679937:BCOP RS04935
gene id: 679937:BCOP_RS04935
uniprot id: F3ZU46
names: Similarity
messages: Belongs to the peptidase S41A family.

679937:BCOP RS11095
gene id: 679937:BCOP_RS11095
uniprot id: F3ZTV7
names: Similarity
messages: Belongs to the aldose epimerase family.

679937:BCOP RS03525
gene id: 679937:BCOP_RS03525
uniprot id: F3ZSM5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

679937:BCOP RS11555
gene id: 679937:BCOP_RS11555
uniprot id: F3ZUI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS11270
gene id: 679937:BCOP_RS11270
uniprot id: F3ZUC7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

679937:BCOP RS07730
gene id: 679937:BCOP_RS07730
uniprot id: F3ZPV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

679937:BCOP RS10460
gene id: 679937:BCOP_RS10460
uniprot id: F3ZSY4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

679937:BCOP RS02155
gene id: 679937:BCOP_RS02155
uniprot id: F3ZR51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

679937:BCOP RS05685
gene id: 679937:BCOP_RS05685
uniprot id: F3ZTR6
names: Similarity
messages: Belongs to the cytochrome c-552 family.

679937:BCOP RS12100
gene id: 679937:BCOP_RS12100
uniprot id: F3ZNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

679937:BCOP RS05935
gene id: 679937:BCOP_RS05935
uniprot id: F3ZUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

679937:BCOP RS02740
gene id: 679937:BCOP_RS02740
uniprot id: F3ZRM3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

679937:BCOP RS12135
gene id: 679937:BCOP_RS12135
uniprot id: F3ZNJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

679937:BCOP RS06850
gene id: 679937:BCOP_RS06850
uniprot id: F3ZNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS11285
gene id: 679937:BCOP_RS11285
uniprot id: F3ZUD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

679937:BCOP RS03160
gene id: 679937:BCOP_RS03160
uniprot id: F3ZS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

679937:BCOP RS12330
gene id: 679937:BCOP_RS12330
uniprot id: F3ZNZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

679937:BCOP RS08135
gene id: 679937:BCOP_RS08135
uniprot id: F3ZQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

679937:BCOP RS09150
gene id: 679937:BCOP_RS09150
uniprot id: F3ZRN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

679937:BCOP RS09880
gene id: 679937:BCOP_RS09880
uniprot id: F3ZSG4
names: Similarity
messages: Belongs to the Dps family.

679937:BCOP RS06305
gene id: 679937:BCOP_RS06305
uniprot id: F3ZUW1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

679937:BCOP RS00155
gene id: 679937:BCOP_RS00155
uniprot id: F3ZNR3
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS04245
gene id: 679937:BCOP_RS04245
uniprot id: F3ZTE0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

679937:BCOP RS07860
gene id: 679937:BCOP_RS07860
uniprot id: F3ZQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

679937:BCOP RS03085
gene id: 679937:BCOP_RS03085
uniprot id: F3ZS12
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

679937:BCOP RS01215
gene id: 679937:BCOP_RS01215
uniprot id: F3ZQ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

679937:BCOP RS06225
gene id: 679937:BCOP_RS06225
uniprot id: F3ZUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

679937:BCOP RS10555
gene id: 679937:BCOP_RS10555
uniprot id: F3ZT75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

679937:BCOP RS12140
gene id: 679937:BCOP_RS12140
uniprot id: F3ZNJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

679937:BCOP RS02940
gene id: 679937:BCOP_RS02940
uniprot id: F3ZRY2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

679937:BCOP RS01550
gene id: 679937:BCOP_RS01550
uniprot id: F3ZQE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

679937:BCOP RS00020
gene id: 679937:BCOP_RS00020
uniprot id: F3ZNN5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

679937:BCOP RS00835
gene id: 679937:BCOP_RS00835
uniprot id: F3ZPM5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

679937:BCOP RS05210
gene id: 679937:BCOP_RS05210
uniprot id: F3ZUN8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

679937:BCOP RS00735
gene id: 679937:BCOP_RS00735
uniprot id: F3ZPK6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

679937:BCOP RS07875
gene id: 679937:BCOP_RS07875
uniprot id: F3ZQ59
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS08045
gene id: 679937:BCOP_RS08045
uniprot id: F3ZQ87
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

679937:BCOP RS07050
gene id: 679937:BCOP_RS07050
uniprot id: F3ZNY4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

679937:BCOP RS09535
gene id: 679937:BCOP_RS09535
uniprot id: F3ZS35
names: Similarity
messages: Belongs to the polysaccharide synthase family.

679937:BCOP RS11470
gene id: 679937:BCOP_RS11470
uniprot id: F3ZUG5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

679937:BCOP RS06385
gene id: 679937:BCOP_RS06385
uniprot id: F3ZUX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

679937:BCOP RS07795
gene id: 679937:BCOP_RS07795
uniprot id: F3ZQ41
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

679937:BCOP RS11510
gene id: 679937:BCOP_RS11510
uniprot id: F3ZUH3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

679937:BCOP RS12775
gene id: 679937:BCOP_RS12775
uniprot id: F3ZPZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

679937:BCOP RS04260
gene id: 679937:BCOP_RS04260
uniprot id: F3ZTE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS03625
gene id: 679937:BCOP_RS03625
uniprot id: F3ZSP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

679937:BCOP RS02825
gene id: 679937:BCOP_RS02825
uniprot id: F3ZRV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS11765
gene id: 679937:BCOP_RS11765
uniprot id: F3ZV07
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS03650
gene id: 679937:BCOP_RS03650
uniprot id: F3ZSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

679937:BCOP RS02935
gene id: 679937:BCOP_RS02935
uniprot id: F3ZRY1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS02900
gene id: 679937:BCOP_RS02900
uniprot id: F3ZRX4
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS03665
gene id: 679937:BCOP_RS03665
uniprot id: F3ZSQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

679937:BCOP RS04635
gene id: 679937:BCOP_RS04635
uniprot id: F3ZTZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS02415
gene id: 679937:BCOP_RS02415
uniprot id: F3ZRG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

679937:BCOP RS00305
gene id: 679937:BCOP_RS00305
uniprot id: F3ZP55
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS01920
gene id: 679937:BCOP_RS01920
uniprot id: F3ZQT9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

679937:BCOP RS02585
gene id: 679937:BCOP_RS02585
uniprot id: F3ZRK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

679937:BCOP RS05815
gene id: 679937:BCOP_RS05815
uniprot id: F3ZU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS02805
gene id: 679937:BCOP_RS02805
uniprot id: F3ZRV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

679937:BCOP RS01175
gene id: 679937:BCOP_RS01175
uniprot id: F3ZQ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

679937:BCOP RS03930
gene id: 679937:BCOP_RS03930
uniprot id: F3ZT08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

679937:BCOP RS08265
gene id: 679937:BCOP_RS08265
uniprot id: F3ZQK1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

679937:BCOP RS03390
gene id: 679937:BCOP_RS03390
uniprot id: F3ZSD5
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS01420
gene id: 679937:BCOP_RS01420
uniprot id: F3ZQB9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

679937:BCOP RS02660
gene id: 679937:BCOP_RS02660
uniprot id: F3ZRL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

679937:BCOP RS01380
gene id: 679937:BCOP_RS01380
uniprot id: F3ZQB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

679937:BCOP RS02885
gene id: 679937:BCOP_RS02885
uniprot id: F3ZRX1
names: Similarity
messages: Belongs to the peptidase U62 family.

679937:BCOP RS05005
gene id: 679937:BCOP_RS05005
uniprot id: F3ZUJ7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

679937:BCOP RS05900
gene id: 679937:BCOP_RS05900
uniprot id: F3ZU94
names: Similarity
messages: Belongs to the class-I fumarase family.

679937:BCOP RS03980
gene id: 679937:BCOP_RS03980
uniprot id: F3ZT18
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

679937:BCOP RS10985
gene id: 679937:BCOP_RS10985
uniprot id: F3ZTT9
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS01195
gene id: 679937:BCOP_RS01195
uniprot id: F3ZQ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

679937:BCOP RS05095
gene id: 679937:BCOP_RS05095
uniprot id: F3ZUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

679937:BCOP RS01820
gene id: 679937:BCOP_RS01820
uniprot id: F3ZQR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

679937:BCOP RS03925
gene id: 679937:BCOP_RS03925
uniprot id: F3ZT07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

679937:BCOP RS06145
gene id: 679937:BCOP_RS06145
uniprot id: F3ZUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

679937:BCOP RS11380
gene id: 679937:BCOP_RS11380
uniprot id: F3ZUE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

679937:BCOP RS00315
gene id: 679937:BCOP_RS00315
uniprot id: F3ZP57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS11575
gene id: 679937:BCOP_RS11575
uniprot id: F3ZUI4
names: Similarity
messages: Belongs to the CapA family.

679937:BCOP RS03865
gene id: 679937:BCOP_RS03865
uniprot id: F3ZSZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

679937:BCOP RS05860
gene id: 679937:BCOP_RS05860
uniprot id: F3ZU86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

679937:BCOP RS06410
gene id: 679937:BCOP_RS06410
uniprot id: F3ZNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

679937:BCOP RS00625
gene id: 679937:BCOP_RS00625
uniprot id: F3ZPI4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

679937:BCOP RS06035
gene id: 679937:BCOP_RS06035
uniprot id: F3ZUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS04280
gene id: 679937:BCOP_RS04280
uniprot id: F3ZTE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

679937:BCOP RS05590
gene id: 679937:BCOP_RS05590
uniprot id: F3ZTP7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

679937:BCOP RS01300
gene id: 679937:BCOP_RS01300
uniprot id: F3ZQ34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

679937:BCOP RS07530
gene id: 679937:BCOP_RS07530
uniprot id: F3ZPR5
names: Subunit
messages: Homodimer.

679937:BCOP RS00230
gene id: 679937:BCOP_RS00230
uniprot id: F3ZNS8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

679937:BCOP RS11490
gene id: 679937:BCOP_RS11490
uniprot id: F3ZUG9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

679937:BCOP RS02910
gene id: 679937:BCOP_RS02910
uniprot id: F3ZRX6
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS12340
gene id: 679937:BCOP_RS12340
uniprot id: F3ZNZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

679937:BCOP RS03680
gene id: 679937:BCOP_RS03680
uniprot id: F3ZSQ3
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS07160
gene id: 679937:BCOP_RS07160
uniprot id: F3ZPC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS00605
gene id: 679937:BCOP_RS00605
uniprot id: F3ZPB2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

679937:BCOP RS03850
gene id: 679937:BCOP_RS03850
uniprot id: F3ZST0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

679937:BCOP RS01210
gene id: 679937:BCOP_RS01210
uniprot id: F3ZQ16
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

679937:BCOP RS12415
gene id: 679937:BCOP_RS12415
uniprot id: F3ZP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

679937:BCOP RS06845
gene id: 679937:BCOP_RS06845
uniprot id: F3ZNU5
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS09955
gene id: 679937:BCOP_RS09955
uniprot id: F3ZSH9
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS00845
gene id: 679937:BCOP_RS00845
uniprot id: F3ZPM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

679937:BCOP RS12640
gene id: 679937:BCOP_RS12640
uniprot id: F3ZPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

679937:BCOP RS03460
gene id: 679937:BCOP_RS03460
uniprot id: F3ZSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

679937:BCOP RS10120
gene id: 679937:BCOP_RS10120
uniprot id: F3ZSL2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

679937:BCOP RS01745
gene id: 679937:BCOP_RS01745
uniprot id: F3ZQQ4
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS11915
gene id: 679937:BCOP_RS11915
uniprot id: F3ZV28
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

679937:BCOP RS00060
gene id: 679937:BCOP_RS00060
uniprot id: F3ZNP3
names: Similarity
messages: Belongs to the peptidase S9A family.

679937:BCOP RS10625
gene id: 679937:BCOP_RS10625
uniprot id: F3ZT89
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS02930
gene id: 679937:BCOP_RS02930
uniprot id: F3ZRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

679937:BCOP RS06835
gene id: 679937:BCOP_RS06835
uniprot id: F3ZNU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

679937:BCOP RS01320
gene id: 679937:BCOP_RS01320
uniprot id: F3ZQ38
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS09470
gene id: 679937:BCOP_RS09470
uniprot id: F3ZS20
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

679937:BCOP RS02030
gene id: 679937:BCOP_RS02030
uniprot id: F3ZQW0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

679937:BCOP RS02330
gene id: 679937:BCOP_RS02330
uniprot id: F3ZR81
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

679937:BCOP RS02520
gene id: 679937:BCOP_RS02520
uniprot id: F3ZRI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

679937:BCOP RS11320
gene id: 679937:BCOP_RS11320
uniprot id: F3ZUD7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

679937:BCOP RS01345
gene id: 679937:BCOP_RS01345
uniprot id: F3ZQA7
names: Subcellular Location Annotation
messages: Cytoplasm

679937:BCOP RS09215
gene id: 679937:BCOP_RS09215
uniprot id: F3ZRQ1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

679937:BCOP RS02010
gene id: 679937:BCOP_RS02010
uniprot id: F3ZQV6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

679937:BCOP RS05325
gene id: 679937:BCOP_RS05325
uniprot id: F3ZT62
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

679937:BCOP RS03985
gene id: 679937:BCOP_RS03985
uniprot id: F3ZT19
names: Similarity
messages: Belongs to the SAICAR synthetase family.

679937:BCOP RS07655
gene id: 679937:BCOP_RS07655
uniprot id: F3ZPU1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

679937:BCOP RS03335
gene id: 679937:BCOP_RS03335
uniprot id: F3ZSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

679937:BCOP RS03605
gene id: 679937:BCOP_RS03605
uniprot id: F3ZSN9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

679937:BCOP RS12530
gene id: 679937:BCOP_RS12530
uniprot id: F3ZP34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

679937:BCOP RS11180
gene id: 679937:BCOP_RS11180
uniprot id: F3ZTX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

679937:BCOP RS10640
gene id: 679937:BCOP_RS10640
uniprot id: F3ZT92
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Fimbrium
messages: Membrane

679937:BCOP RS09345
gene id: 679937:BCOP_RS09345
uniprot id: F3ZRS7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS00655
gene id: 679937:BCOP_RS00655
uniprot id: F3ZPJ0
names: Similarity
messages: Belongs to the RecJ family.

679937:BCOP RS05410
gene id: 679937:BCOP_RS05410
uniprot id: F3ZTL1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

679937:BCOP RS01930
gene id: 679937:BCOP_RS01930
uniprot id: F3ZQU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS03240
gene id: 679937:BCOP_RS03240
uniprot id: F3ZSA6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

679937:BCOP RS11370
gene id: 679937:BCOP_RS11370
uniprot id: F3ZUE7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

679937:BCOP RS08495
gene id: 679937:BCOP_RS08495
uniprot id: F3ZQX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

679937:BCOP RS03385
gene id: 679937:BCOP_RS03385
uniprot id: F3ZSD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS06135
gene id: 679937:BCOP_RS06135
uniprot id: F3ZUS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

679937:BCOP RS04625
gene id: 679937:BCOP_RS04625
uniprot id: F3ZTZ5
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS02870
gene id: 679937:BCOP_RS02870
uniprot id: F3ZRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

679937:BCOP RS01610
gene id: 679937:BCOP_RS01610
uniprot id: F3ZQF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

679937:BCOP RS08320
gene id: 679937:BCOP_RS08320
uniprot id: F3ZQL2
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

679937:BCOP RS01280
gene id: 679937:BCOP_RS01280
uniprot id: F3ZQ30
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

679937:BCOP RS02400
gene id: 679937:BCOP_RS02400
uniprot id: F3ZR95
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS10065
gene id: 679937:BCOP_RS10065
uniprot id: F3ZSK1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

679937:BCOP RS02455
gene id: 679937:BCOP_RS02455
uniprot id: F3ZRH4
names: Similarity
messages: Belongs to the ribF family.

679937:BCOP RS09530
gene id: 679937:BCOP_RS09530
uniprot id: F3ZS34
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

679937:BCOP RS01115
gene id: 679937:BCOP_RS01115
uniprot id: F3ZPZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

679937:BCOP RS05230
gene id: 679937:BCOP_RS05230
uniprot id: F3ZUP1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

679937:BCOP RS07170
gene id: 679937:BCOP_RS07170
uniprot id: F3ZPC5
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

679937:BCOP RS06770
gene id: 679937:BCOP_RS06770
uniprot id: F3ZNT1
names: Similarity
messages: Belongs to the Skp family.

679937:BCOP RS05495
gene id: 679937:BCOP_RS05495
uniprot id: F3ZTM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

679937:BCOP RS05445
gene id: 679937:BCOP_RS05445
uniprot id: F3ZTL8
names: Similarity
messages: Belongs to the peptidase C40 family.

679937:BCOP RS11500
gene id: 679937:BCOP_RS11500
uniprot id: F3ZUH1
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS10740
gene id: 679937:BCOP_RS10740
uniprot id: F3ZTA7
names: Similarity
messages: Belongs to the heat shock protein 90 family.

679937:BCOP RS05925
gene id: 679937:BCOP_RS05925
uniprot id: F3ZU99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

679937:BCOP RS01450
gene id: 679937:BCOP_RS01450
uniprot id: F3ZQC5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

679937:BCOP RS03630
gene id: 679937:BCOP_RS03630
uniprot id: F3ZSP4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

679937:BCOP RS01190
gene id: 679937:BCOP_RS01190
uniprot id: F3ZQ12
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

679937:BCOP RS00040
gene id: 679937:BCOP_RS00040
uniprot id: F3ZNN9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

679937:BCOP RS08525
gene id: 679937:BCOP_RS08525
uniprot id: F3ZQX6
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

679937:BCOP RS01180
gene id: 679937:BCOP_RS01180
uniprot id: F3ZQ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

679937:BCOP RS00250
gene id: 679937:BCOP_RS00250
uniprot id: F3ZP44
names: Similarity
messages: Belongs to the YicC/YloC family.

679937:BCOP RS12130
gene id: 679937:BCOP_RS12130
uniprot id: F3ZNJ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS00850
gene id: 679937:BCOP_RS00850
uniprot id: F3ZPM8
names: Similarity
messages: Belongs to the peptidase S8 family.

679937:BCOP RS01950
gene id: 679937:BCOP_RS01950
uniprot id: F3ZQU5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS06150
gene id: 679937:BCOP_RS06150
uniprot id: F3ZUT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

679937:BCOP RS04360
gene id: 679937:BCOP_RS04360
uniprot id: F3ZTG0
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

679937:BCOP RS03405
gene id: 679937:BCOP_RS03405
uniprot id: F3ZSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

679937:BCOP RS12425
gene id: 679937:BCOP_RS12425
uniprot id: F3ZP14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

679937:BCOP RS05845
gene id: 679937:BCOP_RS05845
uniprot id: F3ZU83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

679937:BCOP RS05255
gene id: 679937:BCOP_RS05255
uniprot id: F3ZUP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS01455
gene id: 679937:BCOP_RS01455
uniprot id: F3ZQC6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

679937:BCOP RS08375
gene id: 679937:BCOP_RS08375
uniprot id: F3ZQM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS00405
gene id: 679937:BCOP_RS00405
uniprot id: F3ZP73
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

679937:BCOP RS00205
gene id: 679937:BCOP_RS00205
uniprot id: F3ZNS3
names: Similarity
messages: Belongs to the peptidase C1 family.

679937:BCOP RS01200
gene id: 679937:BCOP_RS01200
uniprot id: F3ZQ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

679937:BCOP RS00215
gene id: 679937:BCOP_RS00215
uniprot id: F3ZNS5
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

679937:BCOP RS12050
gene id: 679937:BCOP_RS12050
uniprot id: F3ZNH8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

679937:BCOP RS01250
gene id: 679937:BCOP_RS01250
uniprot id: F3ZQ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

679937:BCOP RS09335
gene id: 679937:BCOP_RS09335
uniprot id: F3ZRS5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS02820
gene id: 679937:BCOP_RS02820
uniprot id: F3ZRV8
names: Similarity
messages: Belongs to the SusD family.

679937:BCOP RS00675
gene id: 679937:BCOP_RS00675
uniprot id: F3ZPJ4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

679937:BCOP RS05055
gene id: 679937:BCOP_RS05055
uniprot id: F3ZUK7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

679937:BCOP RS01830
gene id: 679937:BCOP_RS01830
uniprot id: F3ZQS1
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS12085
gene id: 679937:BCOP_RS12085
uniprot id: F3ZNI5
names: Similarity
messages: Belongs to the NusB family.

679937:BCOP RS01080
gene id: 679937:BCOP_RS01080
uniprot id: F3ZPY9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

679937:BCOP RS12070
gene id: 679937:BCOP_RS12070
uniprot id: F3ZNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

679937:BCOP RS01050
gene id: 679937:BCOP_RS01050
uniprot id: F3ZPY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

679937:BCOP RS03495
gene id: 679937:BCOP_RS03495
uniprot id: F3ZSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

679937:BCOP RS00385
gene id: 679937:BCOP_RS00385
uniprot id: F3ZP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

679937:BCOP RS12525
gene id: 679937:BCOP_RS12525
uniprot id: F3ZP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

679937:BCOP RS12105
gene id: 679937:BCOP_RS12105
uniprot id: F3ZNI9
names: Similarity
messages: Belongs to the HSP15 family.

679937:BCOP RS02150
gene id: 679937:BCOP_RS02150
uniprot id: F3ZR50
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS02375
gene id: 679937:BCOP_RS02375
uniprot id: F3ZR90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

679937:BCOP RS03050
gene id: 679937:BCOP_RS03050
uniprot id: F3ZS05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

679937:BCOP RS02650
gene id: 679937:BCOP_RS02650
uniprot id: F3ZRK9
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

679937:BCOP RS10125
gene id: 679937:BCOP_RS10125
uniprot id: F3ZSL3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

679937:BCOP RS11925
gene id: 679937:BCOP_RS11925
uniprot id: F3ZV30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS10000
gene id: 679937:BCOP_RS10000
uniprot id: F3ZSI8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

679937:BCOP RS01690
gene id: 679937:BCOP_RS01690
uniprot id: F3ZQP4
names: Similarity
messages: Belongs to the DapB family.

679937:BCOP RS10560
gene id: 679937:BCOP_RS10560
uniprot id: F3ZT76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

679937:BCOP RS05085
gene id: 679937:BCOP_RS05085
uniprot id: F3ZUL3
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS09875
gene id: 679937:BCOP_RS09875
uniprot id: F3ZSG3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

679937:BCOP RS01525
gene id: 679937:BCOP_RS01525
uniprot id: F3ZQE1
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS04845
gene id: 679937:BCOP_RS04845
uniprot id: F3ZU36
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

679937:BCOP RS06795
gene id: 679937:BCOP_RS06795
uniprot id: F3ZNT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

679937:BCOP RS06235
gene id: 679937:BCOP_RS06235
uniprot id: F3ZUU7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

679937:BCOP RS02405
gene id: 679937:BCOP_RS02405
uniprot id: F3ZRG4
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS02920
gene id: 679937:BCOP_RS02920
uniprot id: F3ZRX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

679937:BCOP RS03355
gene id: 679937:BCOP_RS03355
uniprot id: F3ZSC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

679937:BCOP RS00420
gene id: 679937:BCOP_RS00420
uniprot id: F3ZP76
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

679937:BCOP RS01445
gene id: 679937:BCOP_RS01445
uniprot id: F3ZQC4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

679937:BCOP RS05045
gene id: 679937:BCOP_RS05045
uniprot id: F3ZUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS02255
gene id: 679937:BCOP_RS02255
uniprot id: F3ZR70
names: Similarity
messages: Belongs to the DprA/Smf family.

679937:BCOP RS08735
gene id: 679937:BCOP_RS08735
uniprot id: F3ZR23
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

679937:BCOP RS09690
gene id: 679937:BCOP_RS09690
uniprot id: F3ZS63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

679937:BCOP RS12040
gene id: 679937:BCOP_RS12040
uniprot id: F3ZNH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

679937:BCOP RS02440
gene id: 679937:BCOP_RS02440
uniprot id: F3ZRH1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

679937:BCOP RS10365
gene id: 679937:BCOP_RS10365
uniprot id: F3ZSW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS04825
gene id: 679937:BCOP_RS04825
uniprot id: F3ZU32
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

679937:BCOP RS04375
gene id: 679937:BCOP_RS04375
uniprot id: F3ZTG3
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

679937:BCOP RS10315
gene id: 679937:BCOP_RS10315
uniprot id: F3ZSV6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

679937:BCOP RS01850
gene id: 679937:BCOP_RS01850
uniprot id: F3ZQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

679937:BCOP RS04770
gene id: 679937:BCOP_RS04770
uniprot id: F3ZU23
names: Similarity
messages: Belongs to the peptidase S24 family.

679937:BCOP RS12670
gene id: 679937:BCOP_RS12670
uniprot id: F3ZR25
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Fimbrium
messages: Membrane

679937:BCOP RS11545
gene id: 679937:BCOP_RS11545
uniprot id: F3ZUH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

679937:BCOP RS10250
gene id: 679937:BCOP_RS10250
uniprot id: F3ZSU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS01775
gene id: 679937:BCOP_RS01775
uniprot id: F3ZQR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS02115
gene id: 679937:BCOP_RS02115
uniprot id: F3ZR43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

679937:BCOP RS00885
gene id: 679937:BCOP_RS00885
uniprot id: F3ZPN5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

679937:BCOP RS02735
gene id: 679937:BCOP_RS02735
uniprot id: F3ZRM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS06345
gene id: 679937:BCOP_RS06345
uniprot id: F3ZUW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

679937:BCOP RS02340
gene id: 679937:BCOP_RS02340
uniprot id: F3ZR83
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

679937:BCOP RS05500
gene id: 679937:BCOP_RS05500
uniprot id: F3ZTM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

679937:BCOP RS01040
gene id: 679937:BCOP_RS01040
uniprot id: F3ZPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

679937:BCOP RS12180
gene id: 679937:BCOP_RS12180
uniprot id: F3ZNK4
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

679937:BCOP RS08680
gene id: 679937:BCOP_RS08680
uniprot id: F3ZR12
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

679937:BCOP RS01945
gene id: 679937:BCOP_RS01945
uniprot id: F3ZQU4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

679937:BCOP RS06315
gene id: 679937:BCOP_RS06315
uniprot id: F3ZUW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

679937:BCOP RS04210
gene id: 679937:BCOP_RS04210
uniprot id: F3ZTD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

679937:BCOP RS06025
gene id: 679937:BCOP_RS06025
uniprot id: F3ZUB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

679937:BCOP RS02045
gene id: 679937:BCOP_RS02045
uniprot id: F3ZQW3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

679937:BCOP RS01460
gene id: 679937:BCOP_RS01460
uniprot id: F3ZQC7
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS00780
gene id: 679937:BCOP_RS00780
uniprot id: F3ZPL5
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

679937:BCOP RS09250
gene id: 679937:BCOP_RS09250
uniprot id: F3ZRQ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

679937:BCOP RS05015
gene id: 679937:BCOP_RS05015
uniprot id: F3ZUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

679937:BCOP RS12200
gene id: 679937:BCOP_RS12200
uniprot id: F3ZNK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

679937:BCOP RS00545
gene id: 679937:BCOP_RS00545
uniprot id: F3ZPA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

679937:BCOP RS07710
gene id: 679937:BCOP_RS07710
uniprot id: F3ZPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

679937:BCOP RS11565
gene id: 679937:BCOP_RS11565
uniprot id: F3ZUI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

679937:BCOP RS05430
gene id: 679937:BCOP_RS05430
uniprot id: F3ZTL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

679937:BCOP RS11300
gene id: 679937:BCOP_RS11300
uniprot id: F3ZUD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

679937:BCOP RS01135
gene id: 679937:BCOP_RS01135
uniprot id: F3ZQ01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

679937:BCOP RS10410
gene id: 679937:BCOP_RS10410
uniprot id: F3ZSX4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS05850
gene id: 679937:BCOP_RS05850
uniprot id: F3ZU84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

679937:BCOP RS03275
gene id: 679937:BCOP_RS03275
uniprot id: F3ZSB3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

679937:BCOP RS10310
gene id: 679937:BCOP_RS10310
uniprot id: F3ZSV5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

679937:BCOP RS06100
gene id: 679937:BCOP_RS06100
uniprot id: F3ZUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS11890
gene id: 679937:BCOP_RS11890
uniprot id: F3ZV24
names: Similarity
messages: Belongs to the RutC family.

679937:BCOP RS12420
gene id: 679937:BCOP_RS12420
uniprot id: F3ZP13
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS02975
gene id: 679937:BCOP_RS02975
uniprot id: F3ZRZ0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

679937:BCOP RS02570
gene id: 679937:BCOP_RS02570
uniprot id: F3ZRJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS04475
gene id: 679937:BCOP_RS04475
uniprot id: F3ZTI2
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

679937:BCOP RS08490
gene id: 679937:BCOP_RS08490
uniprot id: F3ZQW9
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

679937:BCOP RS09255
gene id: 679937:BCOP_RS09255
uniprot id: F3ZRQ7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

679937:BCOP RS02560
gene id: 679937:BCOP_RS02560
uniprot id: F3ZRJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

679937:BCOP RS06160
gene id: 679937:BCOP_RS06160
uniprot id: F3ZUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

679937:BCOP RS07125
gene id: 679937:BCOP_RS07125
uniprot id: F3ZPB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

679937:BCOP RS05485
gene id: 679937:BCOP_RS05485
uniprot id: F3ZTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

679937:BCOP RS02970
gene id: 679937:BCOP_RS02970
uniprot id: F3ZRY9
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

679937:BCOP RS03305
gene id: 679937:BCOP_RS03305
uniprot id: F3ZSB9
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

679937:BCOP RS10060
gene id: 679937:BCOP_RS10060
uniprot id: F3ZSK0
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS10575
gene id: 679937:BCOP_RS10575
uniprot id: F3ZT79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

679937:BCOP RS04095
gene id: 679937:BCOP_RS04095
uniprot id: F3ZT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

679937:BCOP RS08515
gene id: 679937:BCOP_RS08515
uniprot id: F3ZQX4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

679937:BCOP RS00300
gene id: 679937:BCOP_RS00300
uniprot id: F3ZP54
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

679937:BCOP RS11035
gene id: 679937:BCOP_RS11035
uniprot id: F3ZTU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

679937:BCOP RS09685
gene id: 679937:BCOP_RS09685
uniprot id: F3ZS62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

679937:BCOP RS12450
gene id: 679937:BCOP_RS12450
uniprot id: F3ZP19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

679937:BCOP RS00620
gene id: 679937:BCOP_RS00620
uniprot id: F3ZPI3
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS00025
gene id: 679937:BCOP_RS00025
uniprot id: F3ZNN6
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

679937:BCOP RS05245
gene id: 679937:BCOP_RS05245
uniprot id: F3ZUP4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

679937:BCOP RS11355
gene id: 679937:BCOP_RS11355
uniprot id: F3ZUE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

679937:BCOP RS06060
gene id: 679937:BCOP_RS06060
uniprot id: F3ZUR2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

679937:BCOP RS02500
gene id: 679937:BCOP_RS02500
uniprot id: F3ZRI3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

679937:BCOP RS12470
gene id: 679937:BCOP_RS12470
uniprot id: F3ZP23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

679937:BCOP RS06300
gene id: 679937:BCOP_RS06300
uniprot id: F3ZUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS08505
gene id: 679937:BCOP_RS08505
uniprot id: F3ZQX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS05090
gene id: 679937:BCOP_RS05090
uniprot id: F3ZUL4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

679937:BCOP RS08740
gene id: 679937:BCOP_RS08740
uniprot id: F3ZR24
names: Similarity
messages: Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.

679937:BCOP RS00015
gene id: 679937:BCOP_RS00015
uniprot id: F3ZNN4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

679937:BCOP RS01405
gene id: 679937:BCOP_RS01405
uniprot id: F3ZQB6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

679937:BCOP RS12205
gene id: 679937:BCOP_RS12205
uniprot id: F3ZNK7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

679937:BCOP RS00345
gene id: 679937:BCOP_RS00345
uniprot id: F3ZP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

679937:BCOP RS03150
gene id: 679937:BCOP_RS03150
uniprot id: F3ZS89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

679937:BCOP RS04710
gene id: 679937:BCOP_RS04710
uniprot id: F3ZU12
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

679937:BCOP RS02485
gene id: 679937:BCOP_RS02485
uniprot id: F3ZRI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

679937:BCOP RS11310
gene id: 679937:BCOP_RS11310
uniprot id: F3ZUD5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

679937:BCOP RS05910
gene id: 679937:BCOP_RS05910
uniprot id: F3ZU96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

679937:BCOP RS03520
gene id: 679937:BCOP_RS03520
uniprot id: F3ZSM4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

679937:BCOP RS00890
gene id: 679937:BCOP_RS00890
uniprot id: F3ZPN6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

679937:BCOP RS09445
gene id: 679937:BCOP_RS09445
uniprot id: F3ZRU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

679937:BCOP RS03075
gene id: 679937:BCOP_RS03075
uniprot id: F3ZS10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

679937:BCOP RS00515
gene id: 679937:BCOP_RS00515
uniprot id: F3ZP94
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

679937:BCOP RS12090
gene id: 679937:BCOP_RS12090
uniprot id: F3ZNI6
names: Subcellular Location Annotation
messages: Nucleus

679937:BCOP RS02995
gene id: 679937:BCOP_RS02995
uniprot id: F3ZRZ4
names: Similarity
messages: Belongs to the UPF0758 family.

679937:BCOP RS08940
gene id: 679937:BCOP_RS08940
uniprot id: F3ZRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

679937:BCOP RS07380
gene id: 679937:BCOP_RS07380
uniprot id: F3ZPG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

679937:BCOP RS10940
gene id: 679937:BCOP_RS10940
uniprot id: F3ZTT0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

679937:BCOP RS09480
gene id: 679937:BCOP_RS09480
uniprot id: F3ZS22
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

679937:BCOP RS05195
gene id: 679937:BCOP_RS05195
uniprot id: F3ZUN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS05635
gene id: 679937:BCOP_RS05635
uniprot id: F3ZTQ6
names: Similarity
messages: Belongs to the peptidase C69 family.

679937:BCOP RS05135
gene id: 679937:BCOP_RS05135
uniprot id: F3ZUM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

679937:BCOP RS05285
gene id: 679937:BCOP_RS05285
uniprot id: F3ZUQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

679937:BCOP RS06175
gene id: 679937:BCOP_RS06175
uniprot id: F3ZUT5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

679937:BCOP RS08895
gene id: 679937:BCOP_RS08895
uniprot id: F3ZRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

679937:BCOP RS00260
gene id: 679937:BCOP_RS00260
uniprot id: F3ZP46
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

679937:BCOP RS12405
gene id: 679937:BCOP_RS12405
uniprot id: F3ZP10
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

679937:BCOP RS10425
gene id: 679937:BCOP_RS10425
uniprot id: F3ZSX7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

679937:BCOP RS11295
gene id: 679937:BCOP_RS11295
uniprot id: F3ZUD2
names: Subcellular Location Annotation
messages: Membrane

679937:BCOP RS01225
gene id: 679937:BCOP_RS01225
uniprot id: F3ZQ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

679937:BCOP RS11425
gene id: 679937:BCOP_RS11425
uniprot id: F3ZUF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

679937:BCOP RS08060
gene id: 679937:BCOP_RS08060
uniprot id: F3ZQ90
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

679937:BCOP RS09245
gene id: 679937:BCOP_RS09245
uniprot id: F3ZRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

679937:BCOP RS06755
gene id: 679937:BCOP_RS06755
uniprot id: F3ZNG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

679937:BCOP RS04815
gene id: 679937:BCOP_RS04815
uniprot id: F3ZU30
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

679937:BCOP RS06120
gene id: 679937:BCOP_RS06120
uniprot id: F3ZUS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

679937:BCOP RS03270
gene id: 679937:BCOP_RS03270
uniprot id: F3ZSB2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

679937:BCOP RS06205
gene id: 679937:BCOP_RS06205
uniprot id: F3ZUU1
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

679937:BCOP RS01865
gene id: 679937:BCOP_RS01865
uniprot id: F3ZQS8
names: Similarity
messages: Belongs to the LOG family.

679937:BCOP RS03325
gene id: 679937:BCOP_RS03325
uniprot id: F3ZSC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

679937:BCOP RS00785
gene id: 679937:BCOP_RS00785
uniprot id: F3ZPL6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

679937:BCOP RS12080
gene id: 679937:BCOP_RS12080
uniprot id: F3ZNI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

679937:BCOP RS12125
gene id: 679937:BCOP_RS12125
uniprot id: F3ZNJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

679937:BCOP RS00190
gene id: 679937:BCOP_RS00190
uniprot id: F3ZNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

679937:BCOP RS03195
gene id: 679937:BCOP_RS03195
uniprot id: F3ZS97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

679937:BCOP RS03110
gene id: 679937:BCOP_RS03110
uniprot id: F3ZS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

679937:BCOP RS01715
gene id: 679937:BCOP_RS01715
uniprot id: F3ZQP9
names: Similarity
messages: Belongs to the LOG family.