67260:CP977 RS20495
gene id: 67260:CP977_RS20495
uniprot id: A0A5J6ISR6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

67260:CP977 RS04595
gene id: 67260:CP977_RS04595
uniprot id: A0A5J6IGL0
names: Similarity
messages: Belongs to the AHA1 family.

67260:CP977 RS12965
gene id: 67260:CP977_RS12965
uniprot id: A0A5J6IKS4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

67260:CP977 RS02880
gene id: 67260:CP977_RS02880
uniprot id: A0A5J6IG58
names: Similarity
messages: Belongs to the asparaginase 1 family.

67260:CP977 RS01565
gene id: 67260:CP977_RS01565
uniprot id: A0A5J6IKA7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

67260:CP977 RS03790
gene id: 67260:CP977_RS03790
uniprot id: A0A5J6ILD9
names: Subcellular Location Annotation
messages: Cytoplasm

67260:CP977 RS29400
gene id: 67260:CP977_RS29400
uniprot id: A0A5J6J7X9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

67260:CP977 RS32950
gene id: 67260:CP977_RS32950
uniprot id: A0A5J6J1V2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

67260:CP977 RS08950
gene id: 67260:CP977_RS08950
uniprot id: A0A5J6ILM7
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS09470
gene id: 67260:CP977_RS09470
uniprot id: A0A5J6INI1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

67260:CP977 RS17565
gene id: 67260:CP977_RS17565
uniprot id: A0A5J6IQ78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

67260:CP977 RS26335
gene id: 67260:CP977_RS26335
uniprot id: A0A5J6IVG5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

67260:CP977 RS25010
gene id: 67260:CP977_RS25010
uniprot id: A0A5J6ITN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

67260:CP977 RS20615
gene id: 67260:CP977_RS20615
uniprot id: A0A5J6ISS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

67260:CP977 RS05455
gene id: 67260:CP977_RS05455
uniprot id: A0A5J6IKJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS20640
gene id: 67260:CP977_RS20640
uniprot id: A0A5J6IP79
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

67260:CP977 RS13635
gene id: 67260:CP977_RS13635
uniprot id: A0A5J6IQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

67260:CP977 RS17920
gene id: 67260:CP977_RS17920
uniprot id: A0A5J6INF1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS32635
gene id: 67260:CP977_RS32635
uniprot id: A0A5J6IZU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

67260:CP977 RS16100
gene id: 67260:CP977_RS16100
uniprot id: A0A5J6IYE2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67260:CP977 RS05320
gene id: 67260:CP977_RS05320
uniprot id: A0A5J6IHB9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS10405
gene id: 67260:CP977_RS10405
uniprot id: A0A5J6IVM3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

67260:CP977 RS05600
gene id: 67260:CP977_RS05600
uniprot id: A0A5J6IS75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS20580
gene id: 67260:CP977_RS20580
uniprot id: A0A5J6IZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

67260:CP977 RS32690
gene id: 67260:CP977_RS32690
uniprot id: A0A5J6IW10
names: Similarity
messages: Belongs to the peptidase C56 family.

67260:CP977 RS25235
gene id: 67260:CP977_RS25235
uniprot id: A0A5J6IXN5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

67260:CP977 RS06320
gene id: 67260:CP977_RS06320
uniprot id: A0A5J6IHU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

67260:CP977 RS27330
gene id: 67260:CP977_RS27330
uniprot id: A0A5J6J3P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

67260:CP977 RS22260
gene id: 67260:CP977_RS22260
uniprot id: A0A5J6IQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

67260:CP977 RS08995
gene id: 67260:CP977_RS08995
uniprot id: A0A5J6IMD4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

67260:CP977 RS08245
gene id: 67260:CP977_RS08245
uniprot id: A0A5J6IWQ7
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS07225
gene id: 67260:CP977_RS07225
uniprot id: A0A5J6IHY0
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

67260:CP977 RS20415
gene id: 67260:CP977_RS20415
uniprot id: A0A5J6IPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67260:CP977 RS06520
gene id: 67260:CP977_RS06520
uniprot id: A0A5J6IWZ2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

67260:CP977 RS09685
gene id: 67260:CP977_RS09685
uniprot id: A0A5J6IJK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS32480
gene id: 67260:CP977_RS32480
uniprot id: A0A5J6IY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

67260:CP977 RS29915
gene id: 67260:CP977_RS29915
uniprot id: A0A5J6IUG4
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS19750
gene id: 67260:CP977_RS19750
uniprot id: A0A5J6IRA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS22460
gene id: 67260:CP977_RS22460
uniprot id: A0A5J6IWA1
names: Similarity
messages: Belongs to the PspA/IM30 family.

67260:CP977 RS03970
gene id: 67260:CP977_RS03970
uniprot id: A0A5J6ILH0
names: Similarity
messages: Belongs to the Fmt family.

67260:CP977 RS24910
gene id: 67260:CP977_RS24910
uniprot id: A0A5J6IXH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

67260:CP977 RS19915
gene id: 67260:CP977_RS19915
uniprot id: A0A5J6ITN6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

67260:CP977 RS22445
gene id: 67260:CP977_RS22445
uniprot id: A0A5J6IV30
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67260:CP977 RS28025
gene id: 67260:CP977_RS28025
uniprot id: A0A5J6IVH8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

67260:CP977 RS12210
gene id: 67260:CP977_RS12210
uniprot id: A0A5J6IMN7
names: Similarity
messages: Belongs to the citrate synthase family.

67260:CP977 RS09745
gene id: 67260:CP977_RS09745
uniprot id: A0A5J6INM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

67260:CP977 RS19745
gene id: 67260:CP977_RS19745
uniprot id: A0A5J6ISE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS02865
gene id: 67260:CP977_RS02865
uniprot id: A0A5J6IFR9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

67260:CP977 RS30210
gene id: 67260:CP977_RS30210
uniprot id: A0A5J6IWD4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

67260:CP977 RS05160
gene id: 67260:CP977_RS05160
uniprot id: A0A5J6IRZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS05290
gene id: 67260:CP977_RS05290
uniprot id: A0A5J6IGZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

67260:CP977 RS32300
gene id: 67260:CP977_RS32300
uniprot id: A0A5J6J5Y0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS13265
gene id: 67260:CP977_RS13265
uniprot id: A0A5J6IKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

67260:CP977 RS17460
gene id: 67260:CP977_RS17460
uniprot id: A0A5J6IY10
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

67260:CP977 RS24475
gene id: 67260:CP977_RS24475
uniprot id: A0A5J6J2E7
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS32600
gene id: 67260:CP977_RS32600
uniprot id: A0A5J6J1P0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

67260:CP977 RS06215
gene id: 67260:CP977_RS06215
uniprot id: A0A5J6IKX5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

67260:CP977 RS14515
gene id: 67260:CP977_RS14515
uniprot id: A0A5J6IQS7
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS25005
gene id: 67260:CP977_RS25005
uniprot id: A0A5J6IUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

67260:CP977 RS11810
gene id: 67260:CP977_RS11810
uniprot id: A0A5J6IRC0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

67260:CP977 RS24355
gene id: 67260:CP977_RS24355
uniprot id: A0A5J6ITH4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

67260:CP977 RS15690
gene id: 67260:CP977_RS15690
uniprot id: A0A5J6IY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS23860
gene id: 67260:CP977_RS23860
uniprot id: A0A5J6IVT5
names: Similarity
messages: Belongs to the UPF0045 family.

67260:CP977 RS03440
gene id: 67260:CP977_RS03440
uniprot id: A0A5J6IL76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67260:CP977 RS20845
gene id: 67260:CP977_RS20845
uniprot id: A0A5J6IWV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

67260:CP977 RS03900
gene id: 67260:CP977_RS03900
uniprot id: A0A5J6IIL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

67260:CP977 RS13260
gene id: 67260:CP977_RS13260
uniprot id: A0A5J6IW08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

67260:CP977 RS24205
gene id: 67260:CP977_RS24205
uniprot id: A0A5J6IR33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS23560
gene id: 67260:CP977_RS23560
uniprot id: A0A5J6IWU9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS08680
gene id: 67260:CP977_RS08680
uniprot id: A0A5J6ITZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

67260:CP977 RS21965
gene id: 67260:CP977_RS21965
uniprot id: A0A5J6IUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

67260:CP977 RS11355
gene id: 67260:CP977_RS11355
uniprot id: A0A5J6IK03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

67260:CP977 RS31125
gene id: 67260:CP977_RS31125
uniprot id: A0A5J6J5E3
names: Similarity
messages: Belongs to the PrpD family.

67260:CP977 RS24020
gene id: 67260:CP977_RS24020
uniprot id: A0A5J6ITB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

67260:CP977 RS04195
gene id: 67260:CP977_RS04195
uniprot id: A0A5J6IJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

67260:CP977 RS14490
gene id: 67260:CP977_RS14490
uniprot id: A0A5J6ILH8
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS24140
gene id: 67260:CP977_RS24140
uniprot id: A0A5J6IX36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

67260:CP977 RS18200
gene id: 67260:CP977_RS18200
uniprot id: A0A5J6IQF3
names: Similarity
messages: Belongs to the YciI family.

67260:CP977 RS20240
gene id: 67260:CP977_RS20240
uniprot id: A0A5J6IPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

67260:CP977 RS18420
gene id: 67260:CP977_RS18420
uniprot id: A0A5J6IN99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

67260:CP977 RS05930
gene id: 67260:CP977_RS05930
uniprot id: A0A5J6IK90
names: Similarity
messages: Belongs to the phosphohexose mutase family.

67260:CP977 RS21690
gene id: 67260:CP977_RS21690
uniprot id: A0A5J6J043
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67260:CP977 RS18385
gene id: 67260:CP977_RS18385
uniprot id: A0A5J6IQI0
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS25215
gene id: 67260:CP977_RS25215
uniprot id: A0A5J6ISE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

67260:CP977 RS19305
gene id: 67260:CP977_RS19305
uniprot id: A0A5J6IS83
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

67260:CP977 RS15720
gene id: 67260:CP977_RS15720
uniprot id: A0A5J6IT38
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

67260:CP977 RS32430
gene id: 67260:CP977_RS32430
uniprot id: A0A5J6IY07
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS32205
gene id: 67260:CP977_RS32205
uniprot id: A0A5J6IXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

67260:CP977 RS23035
gene id: 67260:CP977_RS23035
uniprot id: A0A5J6ISV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS23100
gene id: 67260:CP977_RS23100
uniprot id: A0A5J6IQB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

67260:CP977 RS28585
gene id: 67260:CP977_RS28585
uniprot id: A0A5J6J3K5
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

67260:CP977 RS31020
gene id: 67260:CP977_RS31020
uniprot id: A0A5J6J5C7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS06455
gene id: 67260:CP977_RS06455
uniprot id: A0A5J6IHJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

67260:CP977 RS21655
gene id: 67260:CP977_RS21655
uniprot id: A0A5J6IT96
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67260:CP977 RS26040
gene id: 67260:CP977_RS26040
uniprot id: A0A5J6ISW1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

67260:CP977 RS17455
gene id: 67260:CP977_RS17455
uniprot id: A0A5J6IQB3
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS14075
gene id: 67260:CP977_RS14075
uniprot id: A0A5J6IWD8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS13575
gene id: 67260:CP977_RS13575
uniprot id: A0A5J6IL94
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

67260:CP977 RS28445
gene id: 67260:CP977_RS28445
uniprot id: A0A5J6IZF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

67260:CP977 RS06920
gene id: 67260:CP977_RS06920
uniprot id: A0A5J6INF7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

67260:CP977 RS27595
gene id: 67260:CP977_RS27595
uniprot id: A0A5J6ITL6
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

67260:CP977 RS07845
gene id: 67260:CP977_RS07845
uniprot id: A0A5J6IL45
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

67260:CP977 RS23090
gene id: 67260:CP977_RS23090
uniprot id: A0A5J6ISW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

67260:CP977 RS25350
gene id: 67260:CP977_RS25350
uniprot id: A0A5J6IXQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS31700
gene id: 67260:CP977_RS31700
uniprot id: A0A5J6J192
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

67260:CP977 RS07395
gene id: 67260:CP977_RS07395
uniprot id: A0A5J6ITX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

67260:CP977 RS25965
gene id: 67260:CP977_RS25965
uniprot id: A0A5J6IRX9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS15780
gene id: 67260:CP977_RS15780
uniprot id: A0A5J6IT47
names: Similarity
messages: Belongs to the UPF0145 family.

67260:CP977 RS21930
gene id: 67260:CP977_RS21930
uniprot id: A0A5J6J083
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

67260:CP977 RS09365
gene id: 67260:CP977_RS09365
uniprot id: A0A5J6IJC9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS23700
gene id: 67260:CP977_RS23700
uniprot id: A0A5J6J136
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

67260:CP977 RS04720
gene id: 67260:CP977_RS04720
uniprot id: A0A5J6IH78
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

67260:CP977 RS24240
gene id: 67260:CP977_RS24240
uniprot id: A0A5J6IX56
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

67260:CP977 RS12130
gene id: 67260:CP977_RS12130
uniprot id: A0A5J6IKS1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

67260:CP977 RS22240
gene id: 67260:CP977_RS22240
uniprot id: A0A5J6J0C7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67260:CP977 RS20200
gene id: 67260:CP977_RS20200
uniprot id: A0A5J6ISL3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

67260:CP977 RS08600
gene id: 67260:CP977_RS08600
uniprot id: A0A5J6IM62
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

67260:CP977 RS05735
gene id: 67260:CP977_RS05735
uniprot id: A0A5J6IHJ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS28210
gene id: 67260:CP977_RS28210
uniprot id: A0A5J6IZB1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

67260:CP977 RS08135
gene id: 67260:CP977_RS08135
uniprot id: A0A5J6IL92
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

67260:CP977 RS22655
gene id: 67260:CP977_RS22655
uniprot id: A0A5J6J1M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

67260:CP977 RS12370
gene id: 67260:CP977_RS12370
uniprot id: A0A5J6IKR3
names: Similarity
messages: Belongs to the TPP enzyme family.

67260:CP977 RS06840
gene id: 67260:CP977_RS06840
uniprot id: A0A5J6IM26
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS02110
gene id: 67260:CP977_RS02110
uniprot id: A0A5J6III6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS22245
gene id: 67260:CP977_RS22245
uniprot id: A0A5J6IPX0
names: Similarity
messages: Belongs to the FBPase class 2 family.

67260:CP977 RS20735
gene id: 67260:CP977_RS20735
uniprot id: A0A5J6IRV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

67260:CP977 RS06580
gene id: 67260:CP977_RS06580
uniprot id: A0A5J6II51
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

67260:CP977 RS02895
gene id: 67260:CP977_RS02895
uniprot id: A0A5J6II47
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

67260:CP977 RS29480
gene id: 67260:CP977_RS29480
uniprot id: A0A5J6IW77
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

67260:CP977 RS13855
gene id: 67260:CP977_RS13855
uniprot id: A0A5J6ILK5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

67260:CP977 RS08065
gene id: 67260:CP977_RS08065
uniprot id: A0A5J6ILX1
names: Similarity
messages: Belongs to the UPF0098 family.

67260:CP977 RS23650
gene id: 67260:CP977_RS23650
uniprot id: A0A5J6IQP1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

67260:CP977 RS22900
gene id: 67260:CP977_RS22900
uniprot id: A0A5J6IRB7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

67260:CP977 RS17740
gene id: 67260:CP977_RS17740
uniprot id: A0A5J6IZK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS12475
gene id: 67260:CP977_RS12475
uniprot id: A0A5J6IVN6
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

67260:CP977 RS12950
gene id: 67260:CP977_RS12950
uniprot id: A0A5J6IRU9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS02715
gene id: 67260:CP977_RS02715
uniprot id: A0A5J6IKU8
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS12115
gene id: 67260:CP977_RS12115
uniprot id: A0A5J6IKF2
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

67260:CP977 RS27850
gene id: 67260:CP977_RS27850
uniprot id: A0A5J6IXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS28030
gene id: 67260:CP977_RS28030
uniprot id: A0A5J6IZ80
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

67260:CP977 RS06560
gene id: 67260:CP977_RS06560
uniprot id: A0A5J6IKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

67260:CP977 RS08780
gene id: 67260:CP977_RS08780
uniprot id: A0A5J6IL29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

67260:CP977 RS33065
gene id: 67260:CP977_RS33065
uniprot id: A0A5J6IXN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

67260:CP977 RS30600
gene id: 67260:CP977_RS30600
uniprot id: A0A5J6IXI1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

67260:CP977 RS33025
gene id: 67260:CP977_RS33025
uniprot id: A0A5J6IVV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

67260:CP977 RS06370
gene id: 67260:CP977_RS06370
uniprot id: A0A5J6IHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

67260:CP977 RS21590
gene id: 67260:CP977_RS21590
uniprot id: A0A5J6IQB5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

67260:CP977 RS17805
gene id: 67260:CP977_RS17805
uniprot id: A0A5J6IND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

67260:CP977 RS27315
gene id: 67260:CP977_RS27315
uniprot id: A0A5J6IV04
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67260:CP977 RS24350
gene id: 67260:CP977_RS24350
uniprot id: A0A5J6IX75
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS04845
gene id: 67260:CP977_RS04845
uniprot id: A0A5J6IH95
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS13735
gene id: 67260:CP977_RS13735
uniprot id: A0A5J6ILB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS18955
gene id: 67260:CP977_RS18955
uniprot id: A0A5J6IT70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS08655
gene id: 67260:CP977_RS08655
uniprot id: A0A5J6IL08
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

67260:CP977 RS03015
gene id: 67260:CP977_RS03015
uniprot id: A0A5J6IVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS25900
gene id: 67260:CP977_RS25900
uniprot id: A0A5J6IUC6
names: Subcellular Location Annotation
messages: Cytoplasm

67260:CP977 RS26085
gene id: 67260:CP977_RS26085
uniprot id: A0A5J6J346
names: Similarity
messages: Belongs to the ABC transporter superfamily.

67260:CP977 RS09675
gene id: 67260:CP977_RS09675
uniprot id: A0A5J6IJ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

67260:CP977 RS04165
gene id: 67260:CP977_RS04165
uniprot id: A0A5J6IRH0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67260:CP977 RS23345
gene id: 67260:CP977_RS23345
uniprot id: A0A5J6IVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS24900
gene id: 67260:CP977_RS24900
uniprot id: A0A5J6IUR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

67260:CP977 RS11990
gene id: 67260:CP977_RS11990
uniprot id: A0A5J6IML2
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

67260:CP977 RS24905
gene id: 67260:CP977_RS24905
uniprot id: A0A5J6ITL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

67260:CP977 RS23230
gene id: 67260:CP977_RS23230
uniprot id: A0A5J6IVH7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67260:CP977 RS24830
gene id: 67260:CP977_RS24830
uniprot id: A0A5J6IRX7
names: Similarity
messages: Belongs to the acylphosphatase family.

67260:CP977 RS28470
gene id: 67260:CP977_RS28470
uniprot id: A0A5J6J491
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS16615
gene id: 67260:CP977_RS16615
uniprot id: A0A5J6IPW5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

67260:CP977 RS10075
gene id: 67260:CP977_RS10075
uniprot id: A0A5J6IJR9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS24915
gene id: 67260:CP977_RS24915
uniprot id: A0A5J6ITY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

67260:CP977 RS25710
gene id: 67260:CP977_RS25710
uniprot id: A0A5J6IV57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

67260:CP977 RS06890
gene id: 67260:CP977_RS06890
uniprot id: A0A5J6II97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

67260:CP977 RS23760
gene id: 67260:CP977_RS23760
uniprot id: A0A5J6IT78
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67260:CP977 RS24995
gene id: 67260:CP977_RS24995
uniprot id: A0A5J6ISB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

67260:CP977 RS23715
gene id: 67260:CP977_RS23715
uniprot id: A0A5J6IRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

67260:CP977 RS18910
gene id: 67260:CP977_RS18910
uniprot id: A0A5J6IS12
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

67260:CP977 RS14200
gene id: 67260:CP977_RS14200
uniprot id: A0A5J6ILC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

67260:CP977 RS14305
gene id: 67260:CP977_RS14305
uniprot id: A0A5J6ILF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67260:CP977 RS22475
gene id: 67260:CP977_RS22475
uniprot id: A0A5J6IQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

67260:CP977 RS03315
gene id: 67260:CP977_RS03315
uniprot id: A0A5J6IIB8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS06550
gene id: 67260:CP977_RS06550
uniprot id: A0A5J6IJU2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

67260:CP977 RS17950
gene id: 67260:CP977_RS17950
uniprot id: A0A5J6IQQ1
names: Similarity
messages: Belongs to the peptidase M24B family.

67260:CP977 RS10595
gene id: 67260:CP977_RS10595
uniprot id: A0A5J6IK18
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS32895
gene id: 67260:CP977_RS32895
uniprot id: A0A5J6IXK3
names: Similarity
messages: Belongs to the YciI family.

67260:CP977 RS06270
gene id: 67260:CP977_RS06270
uniprot id: A0A5J6IKY4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

67260:CP977 RS31050
gene id: 67260:CP977_RS31050
uniprot id: A0A5J6J0Z7
names: Similarity
messages: Belongs to the PrpD family.

67260:CP977 RS11435
gene id: 67260:CP977_RS11435
uniprot id: A0A5J6INI6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

67260:CP977 RS22545
gene id: 67260:CP977_RS22545
uniprot id: A0A5J6IQV7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

67260:CP977 RS06205
gene id: 67260:CP977_RS06205
uniprot id: A0A5J6IHS2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

67260:CP977 RS26910
gene id: 67260:CP977_RS26910
uniprot id: A0A5J6IUX5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

67260:CP977 RS07885
gene id: 67260:CP977_RS07885
uniprot id: A0A5J6ILQ1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67260:CP977 RS20680
gene id: 67260:CP977_RS20680
uniprot id: A0A5J6IVE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

67260:CP977 RS19065
gene id: 67260:CP977_RS19065
uniprot id: A0A5J6INJ6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

67260:CP977 RS24645
gene id: 67260:CP977_RS24645
uniprot id: A0A5J6IXB7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

67260:CP977 RS08485
gene id: 67260:CP977_RS08485
uniprot id: A0A5J6IM40
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS26245
gene id: 67260:CP977_RS26245
uniprot id: A0A5J6J373
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

67260:CP977 RS06590
gene id: 67260:CP977_RS06590
uniprot id: A0A5J6ILY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

67260:CP977 RS26535
gene id: 67260:CP977_RS26535
uniprot id: A0A5J6J1T4
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS27840
gene id: 67260:CP977_RS27840
uniprot id: A0A5J6ITH5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

67260:CP977 RS06010
gene id: 67260:CP977_RS06010
uniprot id: A0A5J6IK99
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67260:CP977 RS08580
gene id: 67260:CP977_RS08580
uniprot id: A0A5J6IUF8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

67260:CP977 RS13665
gene id: 67260:CP977_RS13665
uniprot id: A0A5J6IL39
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

67260:CP977 RS07230
gene id: 67260:CP977_RS07230
uniprot id: A0A5J6ITU7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

67260:CP977 RS06525
gene id: 67260:CP977_RS06525
uniprot id: A0A5J6II41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

67260:CP977 RS11585
gene id: 67260:CP977_RS11585
uniprot id: A0A5J6IK42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

67260:CP977 RS14630
gene id: 67260:CP977_RS14630
uniprot id: A0A5J6IQU3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67260:CP977 RS35225
gene id: 67260:CP977_RS35225
uniprot id: A0A5J6IUV9
names: Subcellular Location Annotation
messages: Cytoplasm

67260:CP977 RS25285
gene id: 67260:CP977_RS25285
uniprot id: A0A5J6IXP5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

67260:CP977 RS05100
gene id: 67260:CP977_RS05100
uniprot id: A0A5J6IM61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

67260:CP977 RS01940
gene id: 67260:CP977_RS01940
uniprot id: A0A5J6IKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS15750
gene id: 67260:CP977_RS15750
uniprot id: A0A5J6IME0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

67260:CP977 RS24290
gene id: 67260:CP977_RS24290
uniprot id: A0A5J6ITB6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS25735
gene id: 67260:CP977_RS25735
uniprot id: A0A5J6J216
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

67260:CP977 RS24845
gene id: 67260:CP977_RS24845
uniprot id: A0A5J6IW98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

67260:CP977 RS22580
gene id: 67260:CP977_RS22580
uniprot id: A0A5J6IWC0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

67260:CP977 RS31595
gene id: 67260:CP977_RS31595
uniprot id: A0A5J6J5L3
names: Similarity
messages: Belongs to the cyt1/cyt2 endotoxin family.

67260:CP977 RS02525
gene id: 67260:CP977_RS02525
uniprot id: A0A5J6IG76
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS20625
gene id: 67260:CP977_RS20625
uniprot id: A0A5J6IVD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

67260:CP977 RS29705
gene id: 67260:CP977_RS29705
uniprot id: A0A5J6IX49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

67260:CP977 RS20630
gene id: 67260:CP977_RS20630
uniprot id: A0A5J6IRS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

67260:CP977 RS20610
gene id: 67260:CP977_RS20610
uniprot id: A0A5J6ITZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

67260:CP977 RS15905
gene id: 67260:CP977_RS15905
uniprot id: A0A5J6IPL7
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

67260:CP977 RS06990
gene id: 67260:CP977_RS06990
uniprot id: A0A5J6IK81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

67260:CP977 RS25280
gene id: 67260:CP977_RS25280
uniprot id: A0A5J6ITS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

67260:CP977 RS23630
gene id: 67260:CP977_RS23630
uniprot id: A0A5J6IT18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

67260:CP977 RS18090
gene id: 67260:CP977_RS18090
uniprot id: A0A5J6IQR6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS09595
gene id: 67260:CP977_RS09595
uniprot id: A0A5J6ILI3
names: Similarity
messages: Belongs to the arsA ATPase family.

67260:CP977 RS11090
gene id: 67260:CP977_RS11090
uniprot id: A0A5J6IP86
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS26035
gene id: 67260:CP977_RS26035
uniprot id: A0A5J6ISH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS19825
gene id: 67260:CP977_RS19825
uniprot id: A0A5J6INV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS32370
gene id: 67260:CP977_RS32370
uniprot id: A0A5J6IZQ4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67260:CP977 RS06585
gene id: 67260:CP977_RS06585
uniprot id: A0A5J6IHZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

67260:CP977 RS29830
gene id: 67260:CP977_RS29830
uniprot id: A0A5J6J0E4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS03150
gene id: 67260:CP977_RS03150
uniprot id: A0A5J6IWE7
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS08765
gene id: 67260:CP977_RS08765
uniprot id: A0A5J6IJ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

67260:CP977 RS24630
gene id: 67260:CP977_RS24630
uniprot id: A0A5J6IW63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

67260:CP977 RS03410
gene id: 67260:CP977_RS03410
uniprot id: A0A5J6IRS6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS32420
gene id: 67260:CP977_RS32420
uniprot id: A0A5J6IZR1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS08645
gene id: 67260:CP977_RS08645
uniprot id: A0A5J6IN21
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS06365
gene id: 67260:CP977_RS06365
uniprot id: A0A5J6II09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

67260:CP977 RS10285
gene id: 67260:CP977_RS10285
uniprot id: A0A5J6IVK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

67260:CP977 RS15845
gene id: 67260:CP977_RS15845
uniprot id: A0A5J6IT56
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

67260:CP977 RS05155
gene id: 67260:CP977_RS05155
uniprot id: A0A5J6IJX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

67260:CP977 RS17120
gene id: 67260:CP977_RS17120
uniprot id: A0A5J6IPZ5
names: Similarity
messages: Belongs to the pirin family.

67260:CP977 RS03265
gene id: 67260:CP977_RS03265
uniprot id: A0A5J6IR23
names: Similarity
messages: Belongs to the CsoR family.

67260:CP977 RS20025
gene id: 67260:CP977_RS20025
uniprot id: A0A5J6ITQ3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

67260:CP977 RS10040
gene id: 67260:CP977_RS10040
uniprot id: A0A5J6IMU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67260:CP977 RS26555
gene id: 67260:CP977_RS26555
uniprot id: A0A5J6ISQ1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

67260:CP977 RS20445
gene id: 67260:CP977_RS20445
uniprot id: A0A5J6IRP9
names: Similarity
messages: Belongs to the UPF0234 family.

67260:CP977 RS05050
gene id: 67260:CP977_RS05050
uniprot id: A0A5J6IRX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

67260:CP977 RS06570
gene id: 67260:CP977_RS06570
uniprot id: A0A5J6IHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

67260:CP977 RS10340
gene id: 67260:CP977_RS10340
uniprot id: A0A5J6IJH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67260:CP977 RS24990
gene id: 67260:CP977_RS24990
uniprot id: A0A5J6IS05
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

67260:CP977 RS21175
gene id: 67260:CP977_RS21175
uniprot id: A0A5J6IU93
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

67260:CP977 RS09300
gene id: 67260:CP977_RS09300
uniprot id: A0A5J6IV03
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

67260:CP977 RS18760
gene id: 67260:CP977_RS18760
uniprot id: A0A5J6IUJ0
names: Similarity
messages: Belongs to the CsoR family.

67260:CP977 RS20720
gene id: 67260:CP977_RS20720
uniprot id: A0A5J6IST9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

67260:CP977 RS24970
gene id: 67260:CP977_RS24970
uniprot id: A0A5J6ITZ0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

67260:CP977 RS07210
gene id: 67260:CP977_RS07210
uniprot id: A0A5J6INK7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

67260:CP977 RS16570
gene id: 67260:CP977_RS16570
uniprot id: A0A5J6IYN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

67260:CP977 RS22510
gene id: 67260:CP977_RS22510
uniprot id: A0A5J6IWB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS16825
gene id: 67260:CP977_RS16825
uniprot id: A0A5J6IN32
names: Subcellular Location Annotation
messages: Cytoplasm

67260:CP977 RS22610
gene id: 67260:CP977_RS22610
uniprot id: A0A5J6IR66
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

67260:CP977 RS11835
gene id: 67260:CP977_RS11835
uniprot id: A0A5J6IWC8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67260:CP977 RS04900
gene id: 67260:CP977_RS04900
uniprot id: A0A5J6ISP6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS13230
gene id: 67260:CP977_RS13230
uniprot id: A0A5J6IN37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

67260:CP977 RS04875
gene id: 67260:CP977_RS04875
uniprot id: A0A5J6IM18
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS08190
gene id: 67260:CP977_RS08190
uniprot id: A0A5J6ITS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67260:CP977 RS05185
gene id: 67260:CP977_RS05185
uniprot id: A0A5J6IL61
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS05245
gene id: 67260:CP977_RS05245
uniprot id: A0A5J6IHB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

67260:CP977 RS18940
gene id: 67260:CP977_RS18940
uniprot id: A0A5J6IZZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS31045
gene id: 67260:CP977_RS31045
uniprot id: A0A5J6IX57
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS06795
gene id: 67260:CP977_RS06795
uniprot id: A0A5J6IL74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

67260:CP977 RS23685
gene id: 67260:CP977_RS23685
uniprot id: A0A5J6IT26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

67260:CP977 RS21355
gene id: 67260:CP977_RS21355
uniprot id: A0A5J6IS28
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

67260:CP977 RS25620
gene id: 67260:CP977_RS25620
uniprot id: A0A5J6ISB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

67260:CP977 RS24340
gene id: 67260:CP977_RS24340
uniprot id: A0A5J6IUH8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

67260:CP977 RS22135
gene id: 67260:CP977_RS22135
uniprot id: A0A5J6IR00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

67260:CP977 RS20290
gene id: 67260:CP977_RS20290
uniprot id: A0A5J6J0J9
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

67260:CP977 RS23355
gene id: 67260:CP977_RS23355
uniprot id: A0A5J6ISX5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

67260:CP977 RS28215
gene id: 67260:CP977_RS28215
uniprot id: A0A5J6IVG0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS17445
gene id: 67260:CP977_RS17445
uniprot id: A0A5J6IQ61
names: Similarity
messages: Belongs to the UPF0749 family.

67260:CP977 RS07405
gene id: 67260:CP977_RS07405
uniprot id: A0A5J6IID4
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

67260:CP977 RS25110
gene id: 67260:CP977_RS25110
uniprot id: A0A5J6IUV4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

67260:CP977 RS14225
gene id: 67260:CP977_RS14225
uniprot id: A0A5J6IPP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

67260:CP977 RS12535
gene id: 67260:CP977_RS12535
uniprot id: A0A5J6IVP6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS22720
gene id: 67260:CP977_RS22720
uniprot id: A0A5J6J1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS20805
gene id: 67260:CP977_RS20805
uniprot id: A0A5J6J0S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

67260:CP977 RS15885
gene id: 67260:CP977_RS15885
uniprot id: A0A5J6IRK8
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

67260:CP977 RS17570
gene id: 67260:CP977_RS17570
uniprot id: A0A5J6IU08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

67260:CP977 RS24530
gene id: 67260:CP977_RS24530
uniprot id: A0A5J6J2G4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67260:CP977 RS11690
gene id: 67260:CP977_RS11690
uniprot id: A0A5J6IR98
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

67260:CP977 RS06785
gene id: 67260:CP977_RS06785
uniprot id: A0A5J6II26
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67260:CP977 RS08555
gene id: 67260:CP977_RS08555
uniprot id: A0A5J6IPL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS06250
gene id: 67260:CP977_RS06250
uniprot id: A0A5J6ITC0
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS09530
gene id: 67260:CP977_RS09530
uniprot id: A0A5J6IMM2
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

67260:CP977 RS16350
gene id: 67260:CP977_RS16350
uniprot id: A0A5J6IMB9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

67260:CP977 RS31035
gene id: 67260:CP977_RS31035
uniprot id: A0A5J6IZ52
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS26030
gene id: 67260:CP977_RS26030
uniprot id: A0A5J6J336
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS23670
gene id: 67260:CP977_RS23670
uniprot id: A0A5J6IVQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS19370
gene id: 67260:CP977_RS19370
uniprot id: A0A5J6IQY1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

67260:CP977 RS23790
gene id: 67260:CP977_RS23790
uniprot id: A0A5J6J253
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS27120
gene id: 67260:CP977_RS27120
uniprot id: A0A5J6IVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

67260:CP977 RS19285
gene id: 67260:CP977_RS19285
uniprot id: A0A5J6J047
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

67260:CP977 RS24690
gene id: 67260:CP977_RS24690
uniprot id: A0A5J6ITH6
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

67260:CP977 RS13785
gene id: 67260:CP977_RS13785
uniprot id: A0A5J6ILC9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

67260:CP977 RS08640
gene id: 67260:CP977_RS08640
uniprot id: A0A5J6IIY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

67260:CP977 RS07190
gene id: 67260:CP977_RS07190
uniprot id: A0A5J6II94
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

67260:CP977 RS28460
gene id: 67260:CP977_RS28460
uniprot id: A0A5J6J3I7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67260:CP977 RS08695
gene id: 67260:CP977_RS08695
uniprot id: A0A5J6IJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

67260:CP977 RS06310
gene id: 67260:CP977_RS06310
uniprot id: A0A5J6II02
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

67260:CP977 RS12145
gene id: 67260:CP977_RS12145
uniprot id: A0A5J6IMM9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS13870
gene id: 67260:CP977_RS13870
uniprot id: A0A5J6IPK0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67260:CP977 RS12415
gene id: 67260:CP977_RS12415
uniprot id: A0A5J6IKS0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS06595
gene id: 67260:CP977_RS06595
uniprot id: A0A5J6IL44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

67260:CP977 RS12310
gene id: 67260:CP977_RS12310
uniprot id: A0A5J6IKQ3
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

67260:CP977 RS19555
gene id: 67260:CP977_RS19555
uniprot id: A0A5J6IRB3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

67260:CP977 RS25260
gene id: 67260:CP977_RS25260
uniprot id: A0A5J6IS54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

67260:CP977 RS07735
gene id: 67260:CP977_RS07735
uniprot id: A0A5J6ITJ3
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

67260:CP977 RS20215
gene id: 67260:CP977_RS20215
uniprot id: A0A5J6IRL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

67260:CP977 RS16865
gene id: 67260:CP977_RS16865
uniprot id: A0A5J6IQ08
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

67260:CP977 RS19520
gene id: 67260:CP977_RS19520
uniprot id: A0A5J6J081
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

67260:CP977 RS05035
gene id: 67260:CP977_RS05035
uniprot id: A0A5J6IJ46
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS31745
gene id: 67260:CP977_RS31745
uniprot id: A0A5J6IXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS33320
gene id: 67260:CP977_RS33320
uniprot id: A0A5J6IW03
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

67260:CP977 RS30230
gene id: 67260:CP977_RS30230
uniprot id: A0A5J6IUK5
names: Similarity
messages: Belongs to the thioesterase family.

67260:CP977 RS21330
gene id: 67260:CP977_RS21330
uniprot id: A0A5J6J105
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

67260:CP977 RS08165
gene id: 67260:CP977_RS08165
uniprot id: A0A5J6IMU6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

67260:CP977 RS13165
gene id: 67260:CP977_RS13165
uniprot id: A0A5J6IQA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

67260:CP977 RS29020
gene id: 67260:CP977_RS29020
uniprot id: A0A5J6IWU1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67260:CP977 RS06600
gene id: 67260:CP977_RS06600
uniprot id: A0A5J6IJV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

67260:CP977 RS11925
gene id: 67260:CP977_RS11925
uniprot id: A0A5J6IRE4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67260:CP977 RS14335
gene id: 67260:CP977_RS14335
uniprot id: A0A5J6INM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67260:CP977 RS26980
gene id: 67260:CP977_RS26980
uniprot id: A0A5J6ISF2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

67260:CP977 RS29850
gene id: 67260:CP977_RS29850
uniprot id: A0A5J6ITT0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS23855
gene id: 67260:CP977_RS23855
uniprot id: A0A5J6J000
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

67260:CP977 RS09335
gene id: 67260:CP977_RS09335
uniprot id: A0A5J6IQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

67260:CP977 RS31290
gene id: 67260:CP977_RS31290
uniprot id: A0A5J6IXG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

67260:CP977 RS11695
gene id: 67260:CP977_RS11695
uniprot id: A0A5J6IMT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

67260:CP977 RS27665
gene id: 67260:CP977_RS27665
uniprot id: A0A5J6IZ10
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS16930
gene id: 67260:CP977_RS16930
uniprot id: A0A5J6IQ17
names: Similarity
messages: Belongs to the universal stress protein A family.

67260:CP977 RS21245
gene id: 67260:CP977_RS21245
uniprot id: A0A5J6IT17
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67260:CP977 RS21510
gene id: 67260:CP977_RS21510
uniprot id: A0A5J6IS57
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS24850
gene id: 67260:CP977_RS24850
uniprot id: A0A5J6IUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

67260:CP977 RS15195
gene id: 67260:CP977_RS15195
uniprot id: A0A5J6IQ54
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS20435
gene id: 67260:CP977_RS20435
uniprot id: A0A5J6IRL5
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

67260:CP977 RS14955
gene id: 67260:CP977_RS14955
uniprot id: A0A5J6IQZ1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

67260:CP977 RS29505
gene id: 67260:CP977_RS29505
uniprot id: A0A5J6ITM4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

67260:CP977 RS20700
gene id: 67260:CP977_RS20700
uniprot id: A0A5J6J0R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

67260:CP977 RS05670
gene id: 67260:CP977_RS05670
uniprot id: A0A5J6IHN6
names: Similarity
messages: Belongs to the thioesterase family.

67260:CP977 RS25790
gene id: 67260:CP977_RS25790
uniprot id: A0A5J6IXX0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

67260:CP977 RS06510
gene id: 67260:CP977_RS06510
uniprot id: A0A5J6IHL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

67260:CP977 RS08355
gene id: 67260:CP977_RS08355
uniprot id: A0A5J6IPI3
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS07180
gene id: 67260:CP977_RS07180
uniprot id: A0A5J6ITT5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

67260:CP977 RS25000
gene id: 67260:CP977_RS25000
uniprot id: A0A5J6IWD1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS12190
gene id: 67260:CP977_RS12190
uniprot id: A0A5J6IKN4
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS07205
gene id: 67260:CP977_RS07205
uniprot id: A0A5J6IKA9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

67260:CP977 RS17605
gene id: 67260:CP977_RS17605
uniprot id: A0A5J6ISG7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

67260:CP977 RS11470
gene id: 67260:CP977_RS11470
uniprot id: A0A5J6IKD2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

67260:CP977 RS12670
gene id: 67260:CP977_RS12670
uniprot id: A0A5J6IQ26
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

67260:CP977 RS11400
gene id: 67260:CP977_RS11400
uniprot id: A0A5J6IV72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

67260:CP977 RS11440
gene id: 67260:CP977_RS11440
uniprot id: A0A5J6IMB3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

67260:CP977 RS09705
gene id: 67260:CP977_RS09705
uniprot id: A0A5J6ILJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

67260:CP977 RS23720
gene id: 67260:CP977_RS23720
uniprot id: A0A5J6IRR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

67260:CP977 RS11780
gene id: 67260:CP977_RS11780
uniprot id: A0A5J6IWB7
names: Similarity
messages: Belongs to the FPG family.

67260:CP977 RS25520
gene id: 67260:CP977_RS25520
uniprot id: A0A5J6IV26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

67260:CP977 RS21495
gene id: 67260:CP977_RS21495
uniprot id: A0A5J6IQP4
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS20975
gene id: 67260:CP977_RS20975
uniprot id: A0A5J6IPD5
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

67260:CP977 RS28095
gene id: 67260:CP977_RS28095
uniprot id: A0A5J6J3C5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

67260:CP977 RS21070
gene id: 67260:CP977_RS21070
uniprot id: A0A5J6IS08
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

67260:CP977 RS17550
gene id: 67260:CP977_RS17550
uniprot id: A0A5J6INH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

67260:CP977 RS15525
gene id: 67260:CP977_RS15525
uniprot id: A0A5J6IY33
names: Similarity
messages: Belongs to the Nth/MutY family.

67260:CP977 RS20770
gene id: 67260:CP977_RS20770
uniprot id: A0A5J6ISU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

67260:CP977 RS05055
gene id: 67260:CP977_RS05055
uniprot id: A0A5J6IGV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

67260:CP977 RS13310
gene id: 67260:CP977_RS13310
uniprot id: A0A5J6IW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS04095
gene id: 67260:CP977_RS04095
uniprot id: A0A5J6IJE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67260:CP977 RS14395
gene id: 67260:CP977_RS14395
uniprot id: A0A5J6IQQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

67260:CP977 RS19615
gene id: 67260:CP977_RS19615
uniprot id: A0A5J6IUW9
names: Subcellular Location Annotation
messages: Cell membrane

67260:CP977 RS15130
gene id: 67260:CP977_RS15130
uniprot id: A0A5J6IM33
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS20440
gene id: 67260:CP977_RS20440
uniprot id: A0A5J6IVA2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

67260:CP977 RS13520
gene id: 67260:CP977_RS13520
uniprot id: A0A5J6IL85
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS23015
gene id: 67260:CP977_RS23015
uniprot id: A0A5J6IVD8
names: Similarity
messages: Belongs to the catalase family.

67260:CP977 RS06645
gene id: 67260:CP977_RS06645
uniprot id: A0A5J6IL54
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS31940
gene id: 67260:CP977_RS31940
uniprot id: A0A5J6IX47
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

67260:CP977 RS21520
gene id: 67260:CP977_RS21520
uniprot id: A0A5J6IS89
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS07900
gene id: 67260:CP977_RS07900
uniprot id: A0A5J6IL53
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

67260:CP977 RS07855
gene id: 67260:CP977_RS07855
uniprot id: A0A5J6ITL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

67260:CP977 RS27825
gene id: 67260:CP977_RS27825
uniprot id: A0A5J6J375
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

67260:CP977 RS23880
gene id: 67260:CP977_RS23880
uniprot id: A0A5J6IWZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

67260:CP977 RS17905
gene id: 67260:CP977_RS17905
uniprot id: A0A5J6IN25
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

67260:CP977 RS05460
gene id: 67260:CP977_RS05460
uniprot id: A0A5J6IJB6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

67260:CP977 RS04200
gene id: 67260:CP977_RS04200
uniprot id: A0A5J6IIR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67260:CP977 RS07525
gene id: 67260:CP977_RS07525
uniprot id: A0A5J6IIJ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS32555
gene id: 67260:CP977_RS32555
uniprot id: A0A5J6IXE6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

67260:CP977 RS07135
gene id: 67260:CP977_RS07135
uniprot id: A0A5J6IID3
names: Similarity
messages: Belongs to the cytochrome P450 family.

67260:CP977 RS19040
gene id: 67260:CP977_RS19040
uniprot id: A0A5J6IQS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

67260:CP977 RS29635
gene id: 67260:CP977_RS29635
uniprot id: A0A5J6IUM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS18350
gene id: 67260:CP977_RS18350
uniprot id: A0A5J6IZT1
names: Similarity
messages: Belongs to the GARS family.

67260:CP977 RS30640
gene id: 67260:CP977_RS30640
uniprot id: A0A5J6IV09
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

67260:CP977 RS05580
gene id: 67260:CP977_RS05580
uniprot id: A0A5J6IKK9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

67260:CP977 RS22625
gene id: 67260:CP977_RS22625
uniprot id: A0A5J6ITQ7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67260:CP977 RS22840
gene id: 67260:CP977_RS22840
uniprot id: A0A5J6IR07
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

67260:CP977 RS15400
gene id: 67260:CP977_RS15400
uniprot id: A0A5J6IM84
names: Similarity
messages: Belongs to the histone deacetylase family.

67260:CP977 RS27745
gene id: 67260:CP977_RS27745
uniprot id: A0A5J6ITP3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67260:CP977 RS29575
gene id: 67260:CP977_RS29575
uniprot id: A0A5J6IUA9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

67260:CP977 RS27995
gene id: 67260:CP977_RS27995
uniprot id: A0A5J6ISV3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67260:CP977 RS02830
gene id: 67260:CP977_RS02830
uniprot id: A0A5J6IJD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

67260:CP977 RS24245
gene id: 67260:CP977_RS24245
uniprot id: A0A5J6ITF2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

67260:CP977 RS23260
gene id: 67260:CP977_RS23260
uniprot id: A0A5J6ISZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

67260:CP977 RS25065
gene id: 67260:CP977_RS25065
uniprot id: A0A5J6IXK4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS10910
gene id: 67260:CP977_RS10910
uniprot id: A0A5J6IK66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS25565
gene id: 67260:CP977_RS25565
uniprot id: A0A5J6IWN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

67260:CP977 RS13820
gene id: 67260:CP977_RS13820
uniprot id: A0A5J6IS96
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS10215
gene id: 67260:CP977_RS10215
uniprot id: A0A5J6IQJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS23210
gene id: 67260:CP977_RS23210
uniprot id: A0A5J6IQC7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS20595
gene id: 67260:CP977_RS20595
uniprot id: A0A5J6IPV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

67260:CP977 RS14505
gene id: 67260:CP977_RS14505
uniprot id: A0A5J6IYT5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

67260:CP977 RS24050
gene id: 67260:CP977_RS24050
uniprot id: A0A5J6IVW5
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS20775
gene id: 67260:CP977_RS20775
uniprot id: A0A5J6IRS7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

67260:CP977 RS01710
gene id: 67260:CP977_RS01710
uniprot id: A0A5J6IIX0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67260:CP977 RS15335
gene id: 67260:CP977_RS15335
uniprot id: A0A5J6IWZ4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67260:CP977 RS19030
gene id: 67260:CP977_RS19030
uniprot id: A0A5J6IT79
names: Similarity
messages: Belongs to the peptidase C40 family.

67260:CP977 RS06575
gene id: 67260:CP977_RS06575
uniprot id: A0A5J6ITI8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

67260:CP977 RS05140
gene id: 67260:CP977_RS05140
uniprot id: A0A5J6IKE7
names: Similarity
messages: Belongs to the peptidase C40 family.

67260:CP977 RS04255
gene id: 67260:CP977_RS04255
uniprot id: A0A5J6IKP5
names: Similarity
messages: Belongs to the terpene synthase family.

67260:CP977 RS07245
gene id: 67260:CP977_RS07245
uniprot id: A0A5J6IM96
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

67260:CP977 RS30685
gene id: 67260:CP977_RS30685
uniprot id: A0A5J6J582
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

67260:CP977 RS06800
gene id: 67260:CP977_RS06800
uniprot id: A0A5J6IJY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS28835
gene id: 67260:CP977_RS28835
uniprot id: A0A5J6IU96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

67260:CP977 RS19880
gene id: 67260:CP977_RS19880
uniprot id: A0A5J6IRF7
names: Similarity
messages: Belongs to the citrate synthase family.

67260:CP977 RS14320
gene id: 67260:CP977_RS14320
uniprot id: A0A5J6ILS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

67260:CP977 RS20205
gene id: 67260:CP977_RS20205
uniprot id: A0A5J6IRH6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

67260:CP977 RS31685
gene id: 67260:CP977_RS31685
uniprot id: A0A5J6IZF0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

67260:CP977 RS25195
gene id: 67260:CP977_RS25195
uniprot id: A0A5J6IRJ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS15910
gene id: 67260:CP977_RS15910
uniprot id: A0A5J6IX91
names: Similarity
messages: Belongs to the asparagine synthetase family.

67260:CP977 RS27480
gene id: 67260:CP977_RS27480
uniprot id: A0A5J6IYX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS06405
gene id: 67260:CP977_RS06405
uniprot id: A0A5J6IHI8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS29150
gene id: 67260:CP977_RS29150
uniprot id: A0A5J6IZV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

67260:CP977 RS22890
gene id: 67260:CP977_RS22890
uniprot id: A0A5J6J1K8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67260:CP977 RS11720
gene id: 67260:CP977_RS11720
uniprot id: A0A5J6IKK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

67260:CP977 RS20890
gene id: 67260:CP977_RS20890
uniprot id: A0A5J6ISV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

67260:CP977 RS30970
gene id: 67260:CP977_RS30970
uniprot id: A0A5J6IUV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS01175
gene id: 67260:CP977_RS01175
uniprot id: A0A5J6IHE0
names: Similarity
messages: Belongs to the EccD/Snm4 family.

67260:CP977 RS23695
gene id: 67260:CP977_RS23695
uniprot id: A0A5J6IT71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

67260:CP977 RS09360
gene id: 67260:CP977_RS09360
uniprot id: A0A5J6IJF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS24865
gene id: 67260:CP977_RS24865
uniprot id: A0A5J6ITX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS28875
gene id: 67260:CP977_RS28875
uniprot id: A0A5J6ITB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS08375
gene id: 67260:CP977_RS08375
uniprot id: A0A5J6IUD1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS21440
gene id: 67260:CP977_RS21440
uniprot id: A0A5J6IQN2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

67260:CP977 RS27845
gene id: 67260:CP977_RS27845
uniprot id: A0A5J6ITR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS22850
gene id: 67260:CP977_RS22850
uniprot id: A0A5J6IVA6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS20955
gene id: 67260:CP977_RS20955
uniprot id: A0A5J6IVJ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67260:CP977 RS20520
gene id: 67260:CP977_RS20520
uniprot id: A0A5J6IZK7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

67260:CP977 RS06880
gene id: 67260:CP977_RS06880
uniprot id: A0A5J6IHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

67260:CP977 RS06430
gene id: 67260:CP977_RS06430
uniprot id: A0A5J6IL15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

67260:CP977 RS21925
gene id: 67260:CP977_RS21925
uniprot id: A0A5J6ISF0
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS21025
gene id: 67260:CP977_RS21025
uniprot id: A0A5J6IZT8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

67260:CP977 RS13850
gene id: 67260:CP977_RS13850
uniprot id: A0A5J6ILD8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

67260:CP977 RS17185
gene id: 67260:CP977_RS17185
uniprot id: A0A5J6IXW1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS28180
gene id: 67260:CP977_RS28180
uniprot id: A0A5J6ITX1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS15790
gene id: 67260:CP977_RS15790
uniprot id: A0A5J6IX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS06125
gene id: 67260:CP977_RS06125
uniprot id: A0A5J6ISP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

67260:CP977 RS19485
gene id: 67260:CP977_RS19485
uniprot id: A0A5J6IR05
names: Similarity
messages: Belongs to the CutC family.

67260:CP977 RS25590
gene id: 67260:CP977_RS25590
uniprot id: A0A5J6IU81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

67260:CP977 RS28055
gene id: 67260:CP977_RS28055
uniprot id: A0A5J6ITM0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

67260:CP977 RS09125
gene id: 67260:CP977_RS09125
uniprot id: A0A5J6IU52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

67260:CP977 RS31645
gene id: 67260:CP977_RS31645
uniprot id: A0A5J6J500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS01545
gene id: 67260:CP977_RS01545
uniprot id: A0A5J6IWN1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67260:CP977 RS22515
gene id: 67260:CP977_RS22515
uniprot id: A0A5J6ISP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS10180
gene id: 67260:CP977_RS10180
uniprot id: A0A5J6IVI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS11865
gene id: 67260:CP977_RS11865
uniprot id: A0A5J6IMJ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS10195
gene id: 67260:CP977_RS10195
uniprot id: A0A5J6INV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

67260:CP977 RS18190
gene id: 67260:CP977_RS18190
uniprot id: A0A5J6IRQ0
names: Similarity
messages: Belongs to the CsoR family.

67260:CP977 RS31090
gene id: 67260:CP977_RS31090
uniprot id: A0A5J6IZ62
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

67260:CP977 RS15610
gene id: 67260:CP977_RS15610
uniprot id: A0A5J6IT19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS15810
gene id: 67260:CP977_RS15810
uniprot id: A0A5J6IY83
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS20535
gene id: 67260:CP977_RS20535
uniprot id: A0A5J6J0N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

67260:CP977 RS14545
gene id: 67260:CP977_RS14545
uniprot id: A0A5J6ILJ3
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS03640
gene id: 67260:CP977_RS03640
uniprot id: A0A5J6IG40
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

67260:CP977 RS13645
gene id: 67260:CP977_RS13645
uniprot id: A0A5J6INB0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67260:CP977 RS23640
gene id: 67260:CP977_RS23640
uniprot id: A0A5J6IT60
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

67260:CP977 RS28765
gene id: 67260:CP977_RS28765
uniprot id: A0A5J6IT97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

67260:CP977 RS05585
gene id: 67260:CP977_RS05585
uniprot id: A0A5J6IJD6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

67260:CP977 RS08630
gene id: 67260:CP977_RS08630
uniprot id: A0A5J6IUG8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

67260:CP977 RS13480
gene id: 67260:CP977_RS13480
uniprot id: A0A5J6IQD1
names: Similarity
messages: Belongs to the UPF0434 family.

67260:CP977 RS11465
gene id: 67260:CP977_RS11465
uniprot id: A0A5J6IW58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

67260:CP977 RS23195
gene id: 67260:CP977_RS23195
uniprot id: A0A5J6ISY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS11675
gene id: 67260:CP977_RS11675
uniprot id: A0A5J6IPI2
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS29510
gene id: 67260:CP977_RS29510
uniprot id: A0A5J6J4S2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

67260:CP977 RS04265
gene id: 67260:CP977_RS04265
uniprot id: A0A5J6IK07
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67260:CP977 RS28730
gene id: 67260:CP977_RS28730
uniprot id: A0A5J6IY90
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS25525
gene id: 67260:CP977_RS25525
uniprot id: A0A5J6ITV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

67260:CP977 RS04405
gene id: 67260:CP977_RS04405
uniprot id: A0A5J6IVY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS11265
gene id: 67260:CP977_RS11265
uniprot id: A0A5J6INF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS07990
gene id: 67260:CP977_RS07990
uniprot id: A0A5J6ILW0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

67260:CP977 RS18215
gene id: 67260:CP977_RS18215
uniprot id: A0A5J6IYE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

67260:CP977 RS12375
gene id: 67260:CP977_RS12375
uniprot id: A0A5J6IKW2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

67260:CP977 RS27155
gene id: 67260:CP977_RS27155
uniprot id: A0A5J6J3L9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67260:CP977 RS11085
gene id: 67260:CP977_RS11085
uniprot id: A0A5J6IK92
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS28850
gene id: 67260:CP977_RS28850
uniprot id: A0A5J6IVX1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

67260:CP977 RS28015
gene id: 67260:CP977_RS28015
uniprot id: A0A5J6IXW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS27685
gene id: 67260:CP977_RS27685
uniprot id: A0A5J6J3U6
names: Similarity
messages: Belongs to the allantoicase family.

67260:CP977 RS07240
gene id: 67260:CP977_RS07240
uniprot id: A0A5J6IIA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

67260:CP977 RS20695
gene id: 67260:CP977_RS20695
uniprot id: A0A5J6IP88
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

67260:CP977 RS07150
gene id: 67260:CP977_RS07150
uniprot id: A0A5J6ILD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

67260:CP977 RS20675
gene id: 67260:CP977_RS20675
uniprot id: A0A5J6IRQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

67260:CP977 RS09940
gene id: 67260:CP977_RS09940
uniprot id: A0A5J6IMS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

67260:CP977 RS20605
gene id: 67260:CP977_RS20605
uniprot id: A0A5J6IQ43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

67260:CP977 RS16915
gene id: 67260:CP977_RS16915
uniprot id: A0A5J6IX77
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67260:CP977 RS30285
gene id: 67260:CP977_RS30285
uniprot id: A0A5J6IUL2
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS31345
gene id: 67260:CP977_RS31345
uniprot id: A0A5J6J139
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

67260:CP977 RS16940
gene id: 67260:CP977_RS16940
uniprot id: A0A5J6IML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS15530
gene id: 67260:CP977_RS15530
uniprot id: A0A5J6IMA4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS02905
gene id: 67260:CP977_RS02905
uniprot id: A0A5J6IIW7
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

67260:CP977 RS18770
gene id: 67260:CP977_RS18770
uniprot id: A0A5J6IYL0
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS31740
gene id: 67260:CP977_RS31740
uniprot id: A0A5J6IY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS05335
gene id: 67260:CP977_RS05335
uniprot id: A0A5J6IKH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

67260:CP977 RS10745
gene id: 67260:CP977_RS10745
uniprot id: A0A5J6IN58
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

67260:CP977 RS20715
gene id: 67260:CP977_RS20715
uniprot id: A0A5J6IU19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

67260:CP977 RS09665
gene id: 67260:CP977_RS09665
uniprot id: A0A5J6ILW6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS19345
gene id: 67260:CP977_RS19345
uniprot id: A0A5J6IPA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

67260:CP977 RS09900
gene id: 67260:CP977_RS09900
uniprot id: A0A5J6IUI4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

67260:CP977 RS13205
gene id: 67260:CP977_RS13205
uniprot id: A0A5J6IL37
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

67260:CP977 RS05400
gene id: 67260:CP977_RS05400
uniprot id: A0A5J6IL91
names: Similarity
messages: Belongs to the IMPACT family.

67260:CP977 RS20915
gene id: 67260:CP977_RS20915
uniprot id: A0A5J6IZS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS13355
gene id: 67260:CP977_RS13355
uniprot id: A0A5J6IPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

67260:CP977 RS09680
gene id: 67260:CP977_RS09680
uniprot id: A0A5J6IV77
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

67260:CP977 RS28735
gene id: 67260:CP977_RS28735
uniprot id: A0A5J6IWP1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

67260:CP977 RS18790
gene id: 67260:CP977_RS18790
uniprot id: A0A5J6INR5
names: Similarity
messages: Belongs to the PstS family.

67260:CP977 RS05120
gene id: 67260:CP977_RS05120
uniprot id: A0A5J6ISS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

67260:CP977 RS20800
gene id: 67260:CP977_RS20800
uniprot id: A0A5J6IPA2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS27905
gene id: 67260:CP977_RS27905
uniprot id: A0A5J6IXU5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

67260:CP977 RS18950
gene id: 67260:CP977_RS18950
uniprot id: A0A5J6IP40
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

67260:CP977 RS28525
gene id: 67260:CP977_RS28525
uniprot id: A0A5J6J4A0
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

67260:CP977 RS32915
gene id: 67260:CP977_RS32915
uniprot id: A0A5J6IVT6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS15740
gene id: 67260:CP977_RS15740
uniprot id: A0A5J6IY72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

67260:CP977 RS06355
gene id: 67260:CP977_RS06355
uniprot id: A0A5J6IHH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

67260:CP977 RS04090
gene id: 67260:CP977_RS04090
uniprot id: A0A5J6ILJ1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS31550
gene id: 67260:CP977_RS31550
uniprot id: A0A5J6IVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS21755
gene id: 67260:CP977_RS21755
uniprot id: A0A5J6IQI5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

67260:CP977 RS31980
gene id: 67260:CP977_RS31980
uniprot id: A0A5J6IY56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

67260:CP977 RS17515
gene id: 67260:CP977_RS17515
uniprot id: A0A5J6IU01
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

67260:CP977 RS28010
gene id: 67260:CP977_RS28010
uniprot id: A0A5J6ITU2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

67260:CP977 RS28580
gene id: 67260:CP977_RS28580
uniprot id: A0A5J6IX88
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67260:CP977 RS15190
gene id: 67260:CP977_RS15190
uniprot id: A0A5J6IR87
names: Similarity
messages: Belongs to the AHA1 family.

67260:CP977 RS11640
gene id: 67260:CP977_RS11640
uniprot id: A0A5J6IMS9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

67260:CP977 RS24685
gene id: 67260:CP977_RS24685
uniprot id: A0A5J6IUM7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

67260:CP977 RS07940
gene id: 67260:CP977_RS07940
uniprot id: A0A5J6IKM9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS11685
gene id: 67260:CP977_RS11685
uniprot id: A0A5J6IMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

67260:CP977 RS24015
gene id: 67260:CP977_RS24015
uniprot id: A0A5J6IX16
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

67260:CP977 RS11730
gene id: 67260:CP977_RS11730
uniprot id: A0A5J6INN6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

67260:CP977 RS19945
gene id: 67260:CP977_RS19945
uniprot id: A0A5J6INX1
names: Similarity
messages: Belongs to the UPF0309 family.

67260:CP977 RS20685
gene id: 67260:CP977_RS20685
uniprot id: A0A5J6IRU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

67260:CP977 RS03730
gene id: 67260:CP977_RS03730
uniprot id: A0A5J6ILD0
names: Similarity
messages: Belongs to the universal stress protein A family.

67260:CP977 RS20175
gene id: 67260:CP977_RS20175
uniprot id: A0A5J6IP07
names: Similarity
messages: Belongs to the peptidase C40 family.

67260:CP977 RS23930
gene id: 67260:CP977_RS23930
uniprot id: A0A5J6IRU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

67260:CP977 RS09710
gene id: 67260:CP977_RS09710
uniprot id: A0A5J6IQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

67260:CP977 RS31885
gene id: 67260:CP977_RS31885
uniprot id: A0A5J6IX38
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67260:CP977 RS26520
gene id: 67260:CP977_RS26520
uniprot id: A0A5J6IUR0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67260:CP977 RS28205
gene id: 67260:CP977_RS28205
uniprot id: A0A5J6IVL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

67260:CP977 RS24100
gene id: 67260:CP977_RS24100
uniprot id: A0A5J6IRL0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67260:CP977 RS22040
gene id: 67260:CP977_RS22040
uniprot id: A0A5J6ISE1
names: Similarity
messages: Belongs to the GSP E family.

67260:CP977 RS09160
gene id: 67260:CP977_RS09160
uniprot id: A0A5J6IL99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS20230
gene id: 67260:CP977_RS20230
uniprot id: A0A5J6J0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67260:CP977 RS12715
gene id: 67260:CP977_RS12715
uniprot id: A0A5J6IWS2
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

67260:CP977 RS08740
gene id: 67260:CP977_RS08740
uniprot id: A0A5J6ITZ7
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

67260:CP977 RS25430
gene id: 67260:CP977_RS25430
uniprot id: A0A5J6ISH2
names: Similarity
messages: Belongs to the peptidase M16 family.

67260:CP977 RS32875
gene id: 67260:CP977_RS32875
uniprot id: A0A5J6IZX1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67260:CP977 RS13620
gene id: 67260:CP977_RS13620
uniprot id: A0A5J6IX62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

67260:CP977 RS15340
gene id: 67260:CP977_RS15340
uniprot id: A0A5J6ILU8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

67260:CP977 RS25025
gene id: 67260:CP977_RS25025
uniprot id: A0A5J6J1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS26510
gene id: 67260:CP977_RS26510
uniprot id: A0A5J6IX32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS14995
gene id: 67260:CP977_RS14995
uniprot id: A0A5J6IXU4
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS17535
gene id: 67260:CP977_RS17535
uniprot id: A0A5J6IZB9
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

67260:CP977 RS11145
gene id: 67260:CP977_RS11145
uniprot id: A0A5J6IKA6
names: Similarity
messages: Belongs to the CutA family.

67260:CP977 RS07435
gene id: 67260:CP977_RS07435
uniprot id: A0A5J6ITE2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67260:CP977 RS23155
gene id: 67260:CP977_RS23155
uniprot id: A0A5J6J1W1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67260:CP977 RS27755
gene id: 67260:CP977_RS27755
uniprot id: A0A5J6IW65
names: Similarity
messages: Belongs to the LOG family.

67260:CP977 RS21380
gene id: 67260:CP977_RS21380
uniprot id: A0A5J6J117
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS24165
gene id: 67260:CP977_RS24165
uniprot id: A0A5J6IRM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS12540
gene id: 67260:CP977_RS12540
uniprot id: A0A5J6IKK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

67260:CP977 RS19130
gene id: 67260:CP977_RS19130
uniprot id: A0A5J6IP58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS08340
gene id: 67260:CP977_RS08340
uniprot id: A0A5J6IMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

67260:CP977 RS21250
gene id: 67260:CP977_RS21250
uniprot id: A0A5J6IS10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS28655
gene id: 67260:CP977_RS28655
uniprot id: A0A5J6J4C2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

67260:CP977 RS10915
gene id: 67260:CP977_RS10915
uniprot id: A0A5J6IP54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

67260:CP977 RS26025
gene id: 67260:CP977_RS26025
uniprot id: A0A5J6IRZ2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

67260:CP977 RS13515
gene id: 67260:CP977_RS13515
uniprot id: A0A5J6IX43
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

67260:CP977 RS06855
gene id: 67260:CP977_RS06855
uniprot id: A0A5J6IK61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

67260:CP977 RS09635
gene id: 67260:CP977_RS09635
uniprot id: A0A5J6IJK6
names: Similarity
messages: Belongs to the peptidase C40 family.

67260:CP977 RS02745
gene id: 67260:CP977_RS02745
uniprot id: A0A5J6IG36
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

67260:CP977 RS21765
gene id: 67260:CP977_RS21765
uniprot id: A0A5J6IUR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

67260:CP977 RS20160
gene id: 67260:CP977_RS20160
uniprot id: A0A5J6IV55
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

67260:CP977 RS20635
gene id: 67260:CP977_RS20635
uniprot id: A0A5J6IZM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

67260:CP977 RS28075
gene id: 67260:CP977_RS28075
uniprot id: A0A5J6IVJ2
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

67260:CP977 RS12545
gene id: 67260:CP977_RS12545
uniprot id: A0A5J6IWP4
names: Similarity
messages: Belongs to the universal stress protein A family.

67260:CP977 RS10325
gene id: 67260:CP977_RS10325
uniprot id: A0A5J6IWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

67260:CP977 RS15140
gene id: 67260:CP977_RS15140
uniprot id: A0A5J6IQ44
names: Similarity
messages: Belongs to the UbiD family.

67260:CP977 RS20815
gene id: 67260:CP977_RS20815
uniprot id: A0A5J6IQ81
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

67260:CP977 RS20940
gene id: 67260:CP977_RS20940
uniprot id: A0A5J6IU59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

67260:CP977 RS21545
gene id: 67260:CP977_RS21545
uniprot id: A0A5J6IQQ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS08395
gene id: 67260:CP977_RS08395
uniprot id: A0A5J6IM30
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

67260:CP977 RS15770
gene id: 67260:CP977_RS15770
uniprot id: A0A5J6IZI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

67260:CP977 RS06390
gene id: 67260:CP977_RS06390
uniprot id: A0A5J6IN74
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS06395
gene id: 67260:CP977_RS06395
uniprot id: A0A5J6IKH0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

67260:CP977 RS28145
gene id: 67260:CP977_RS28145
uniprot id: A0A5J6IZA1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

67260:CP977 RS26305
gene id: 67260:CP977_RS26305
uniprot id: A0A5J6J2A8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67260:CP977 RS14155
gene id: 67260:CP977_RS14155
uniprot id: A0A5J6IXE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS07090
gene id: 67260:CP977_RS07090
uniprot id: A0A5J6IM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

67260:CP977 RS08615
gene id: 67260:CP977_RS08615
uniprot id: A0A5J6ILH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS31695
gene id: 67260:CP977_RS31695
uniprot id: A0A5J6IXN1
names: Similarity
messages: Belongs to the asparagine synthetase family.

67260:CP977 RS13335
gene id: 67260:CP977_RS13335
uniprot id: A0A5J6IL58
names: Similarity
messages: Belongs to the peptidase C56 family.

67260:CP977 RS20970
gene id: 67260:CP977_RS20970
uniprot id: A0A5J6IZS9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

67260:CP977 RS17695
gene id: 67260:CP977_RS17695
uniprot id: A0A5J6INA6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

67260:CP977 RS15360
gene id: 67260:CP977_RS15360
uniprot id: A0A5J6IRB5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

67260:CP977 RS04105
gene id: 67260:CP977_RS04105
uniprot id: A0A5J6IGC1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS07995
gene id: 67260:CP977_RS07995
uniprot id: A0A5J6IKP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS27990
gene id: 67260:CP977_RS27990
uniprot id: A0A5J6J3A7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

67260:CP977 RS30605
gene id: 67260:CP977_RS30605
uniprot id: A0A5J6IWQ5
names: Similarity
messages: Belongs to the melC1 family.

67260:CP977 RS10050
gene id: 67260:CP977_RS10050
uniprot id: A0A5J6IQG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67260:CP977 RS13590
gene id: 67260:CP977_RS13590
uniprot id: A0A5J6IPF1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

67260:CP977 RS30535
gene id: 67260:CP977_RS30535
uniprot id: A0A5J6IUZ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS17520
gene id: 67260:CP977_RS17520
uniprot id: A0A5J6IQG7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

67260:CP977 RS32610
gene id: 67260:CP977_RS32610
uniprot id: A0A5J6J5J4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

67260:CP977 RS23885
gene id: 67260:CP977_RS23885
uniprot id: A0A5J6IT95
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

67260:CP977 RS19950
gene id: 67260:CP977_RS19950
uniprot id: A0A5J6J0E0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS11740
gene id: 67260:CP977_RS11740
uniprot id: A0A5J6IMH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

67260:CP977 RS19340
gene id: 67260:CP977_RS19340
uniprot id: A0A5J6J056
names: Subcellular Location Annotation
messages: Cytoplasm

67260:CP977 RS16195
gene id: 67260:CP977_RS16195
uniprot id: A0A5J6ITC6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS17555
gene id: 67260:CP977_RS17555
uniprot id: A0A5J6ISG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

67260:CP977 RS21125
gene id: 67260:CP977_RS21125
uniprot id: A0A5J6IU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

67260:CP977 RS15745
gene id: 67260:CP977_RS15745
uniprot id: A0A5J6IZR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

67260:CP977 RS11455
gene id: 67260:CP977_RS11455
uniprot id: A0A5J6IV82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

67260:CP977 RS09500
gene id: 67260:CP977_RS09500
uniprot id: A0A5J6IJ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

67260:CP977 RS22605
gene id: 67260:CP977_RS22605
uniprot id: A0A5J6IQW6
names: Similarity
messages: Belongs to the LOG family.

67260:CP977 RS26940
gene id: 67260:CP977_RS26940
uniprot id: A0A5J6IT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS08745
gene id: 67260:CP977_RS08745
uniprot id: A0A5J6IZ48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

67260:CP977 RS08055
gene id: 67260:CP977_RS08055
uniprot id: A0A5J6IIP1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

67260:CP977 RS29520
gene id: 67260:CP977_RS29520
uniprot id: A0A5J6IUK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

67260:CP977 RS16145
gene id: 67260:CP977_RS16145
uniprot id: A0A5J6ITB4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

67260:CP977 RS03615
gene id: 67260:CP977_RS03615
uniprot id: A0A5J6IJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

67260:CP977 RS29900
gene id: 67260:CP977_RS29900
uniprot id: A0A5J6J460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

67260:CP977 RS21145
gene id: 67260:CP977_RS21145
uniprot id: A0A5J6IS16
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

67260:CP977 RS08170
gene id: 67260:CP977_RS08170
uniprot id: A0A5J6ILY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

67260:CP977 RS13555
gene id: 67260:CP977_RS13555
uniprot id: A0A5J6IW54
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

67260:CP977 RS16290
gene id: 67260:CP977_RS16290
uniprot id: A0A5J6J743
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

67260:CP977 RS25015
gene id: 67260:CP977_RS25015
uniprot id: A0A5J6IXJ3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

67260:CP977 RS27500
gene id: 67260:CP977_RS27500
uniprot id: A0A5J6J7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS09305
gene id: 67260:CP977_RS09305
uniprot id: A0A5J6IJE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

67260:CP977 RS21140
gene id: 67260:CP977_RS21140
uniprot id: A0A5J6IVM5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

67260:CP977 RS20245
gene id: 67260:CP977_RS20245
uniprot id: A0A5J6ITU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67260:CP977 RS08075
gene id: 67260:CP977_RS08075
uniprot id: A0A5J6IPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS07305
gene id: 67260:CP977_RS07305
uniprot id: A0A5J6ILF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

67260:CP977 RS15365
gene id: 67260:CP977_RS15365
uniprot id: A0A5J6IQ84
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS20570
gene id: 67260:CP977_RS20570
uniprot id: A0A5J6IVC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

67260:CP977 RS13550
gene id: 67260:CP977_RS13550
uniprot id: A0A5J6INM2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

67260:CP977 RS15710
gene id: 67260:CP977_RS15710
uniprot id: A0A5J6IQH3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

67260:CP977 RS11940
gene id: 67260:CP977_RS11940
uniprot id: A0A5J6IVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS12900
gene id: 67260:CP977_RS12900
uniprot id: A0A5J6INB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

67260:CP977 RS28645
gene id: 67260:CP977_RS28645
uniprot id: A0A5J6J3L1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS12665
gene id: 67260:CP977_RS12665
uniprot id: A0A5J6IL13
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

67260:CP977 RS16605
gene id: 67260:CP977_RS16605
uniprot id: A0A5J6IPQ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

67260:CP977 RS29840
gene id: 67260:CP977_RS29840
uniprot id: A0A5J6J454
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

67260:CP977 RS24945
gene id: 67260:CP977_RS24945
uniprot id: A0A5J6IWC2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

67260:CP977 RS09180
gene id: 67260:CP977_RS09180
uniprot id: A0A5J6IIW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

67260:CP977 RS09195
gene id: 67260:CP977_RS09195
uniprot id: A0A5J6IJ99
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

67260:CP977 RS15350
gene id: 67260:CP977_RS15350
uniprot id: A0A5J6IM77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

67260:CP977 RS20575
gene id: 67260:CP977_RS20575
uniprot id: A0A5J6IRR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

67260:CP977 RS14000
gene id: 67260:CP977_RS14000
uniprot id: A0A5J6INU0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

67260:CP977 RS17525
gene id: 67260:CP977_RS17525
uniprot id: A0A5J6IY23
names: Similarity
messages: Belongs to the UPF0232 family.

67260:CP977 RS23625
gene id: 67260:CP977_RS23625
uniprot id: A0A5J6IU76
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

67260:CP977 RS05920
gene id: 67260:CP977_RS05920
uniprot id: A0A5J6IJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

67260:CP977 RS24550
gene id: 67260:CP977_RS24550
uniprot id: A0A5J6IW51
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67260:CP977 RS05605
gene id: 67260:CP977_RS05605
uniprot id: A0A5J6IH46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS22010
gene id: 67260:CP977_RS22010
uniprot id: A0A5J6J1J0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

67260:CP977 RS32180
gene id: 67260:CP977_RS32180
uniprot id: A0A5J6IVR9
names: Similarity
messages: Belongs to the peptidase S8 family.

67260:CP977 RS32565
gene id: 67260:CP977_RS32565
uniprot id: A0A5J6IV29
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

67260:CP977 RS28165
gene id: 67260:CP977_RS28165
uniprot id: A0A5J6J432
names: Similarity
messages: Belongs to the CdaR family.

67260:CP977 RS18765
gene id: 67260:CP977_RS18765
uniprot id: A0A5J6IR03
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

67260:CP977 RS06245
gene id: 67260:CP977_RS06245
uniprot id: A0A5J6IHG1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67260:CP977 RS16515
gene id: 67260:CP977_RS16515
uniprot id: A0A5J6IYM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

67260:CP977 RS20600
gene id: 67260:CP977_RS20600
uniprot id: A0A5J6IZ44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

67260:CP977 RS25915
gene id: 67260:CP977_RS25915
uniprot id: A0A5J6J316
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

67260:CP977 RS13475
gene id: 67260:CP977_RS13475
uniprot id: A0A5J6ILD7
names: Similarity
messages: Belongs to the PGI/PMI family.

67260:CP977 RS21420
gene id: 67260:CP977_RS21420
uniprot id: A0A5J6IZZ4
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

67260:CP977 RS20480
gene id: 67260:CP977_RS20480
uniprot id: A0A5J6IPT5
names: Similarity
messages: Belongs to the UPF0336 family.

67260:CP977 RS10870
gene id: 67260:CP977_RS10870
uniprot id: A0A5J6IM06
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

67260:CP977 RS21345
gene id: 67260:CP977_RS21345
uniprot id: A0A5J6IUB7
names: Similarity
messages: Belongs to the cytochrome b560 family.

67260:CP977 RS23800
gene id: 67260:CP977_RS23800
uniprot id: A0A5J6IRS5
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS31975
gene id: 67260:CP977_RS31975
uniprot id: A0A5J6IZJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67260:CP977 RS24010
gene id: 67260:CP977_RS24010
uniprot id: A0A5J6IT69
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

67260:CP977 RS11290
gene id: 67260:CP977_RS11290
uniprot id: A0A5J6J6V6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

67260:CP977 RS12560
gene id: 67260:CP977_RS12560
uniprot id: A0A5J6IQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

67260:CP977 RS14105
gene id: 67260:CP977_RS14105
uniprot id: A0A5J6IPN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

67260:CP977 RS16610
gene id: 67260:CP977_RS16610
uniprot id: A0A5J6ITJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

67260:CP977 RS07800
gene id: 67260:CP977_RS07800
uniprot id: A0A5J6ITK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

67260:CP977 RS17680
gene id: 67260:CP977_RS17680
uniprot id: A0A5J6IY53
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

67260:CP977 RS24230
gene id: 67260:CP977_RS24230
uniprot id: A0A5J6IUG0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

67260:CP977 RS12795
gene id: 67260:CP977_RS12795
uniprot id: A0A5J6IKX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

67260:CP977 RS33450
gene id: 67260:CP977_RS33450
uniprot id: A0A5J6IY15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

67260:CP977 RS13045
gene id: 67260:CP977_RS13045
uniprot id: A0A5J6IP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67260:CP977 RS02815
gene id: 67260:CP977_RS02815
uniprot id: A0A5J6IGC2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

67260:CP977 RS20920
gene id: 67260:CP977_RS20920
uniprot id: A0A5J6IPD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS06720
gene id: 67260:CP977_RS06720
uniprot id: A0A5J6IJX2
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

67260:CP977 RS08175
gene id: 67260:CP977_RS08175
uniprot id: A0A5J6IKR9
names: Similarity
messages: Belongs to the peptidase U62 family.

67260:CP977 RS20510
gene id: 67260:CP977_RS20510
uniprot id: A0A5J6IVB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

67260:CP977 RS21705
gene id: 67260:CP977_RS21705
uniprot id: A0A5J6IQH2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

67260:CP977 RS10830
gene id: 67260:CP977_RS10830
uniprot id: A0A5J6IJQ9
names: Similarity
messages: Belongs to the FemABX family.

67260:CP977 RS15445
gene id: 67260:CP977_RS15445
uniprot id: A0A5J6IPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

67260:CP977 RS03780
gene id: 67260:CP977_RS03780
uniprot id: A0A5J6IJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

67260:CP977 RS15085
gene id: 67260:CP977_RS15085
uniprot id: A0A5J6INY9
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

67260:CP977 RS09255
gene id: 67260:CP977_RS09255
uniprot id: A0A5J6IJB0
names: Subcellular Location Annotation
messages: Cytoplasm

67260:CP977 RS28705
gene id: 67260:CP977_RS28705
uniprot id: A0A5J6J3M0
names: Similarity
messages: Belongs to the YciI family.

67260:CP977 RS21595
gene id: 67260:CP977_RS21595
uniprot id: A0A5J6IQR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

67260:CP977 RS19365
gene id: 67260:CP977_RS19365
uniprot id: A0A5J6IS93
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS06225
gene id: 67260:CP977_RS06225
uniprot id: A0A5J6IW32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

67260:CP977 RS20665
gene id: 67260:CP977_RS20665
uniprot id: A0A5J6IST4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

67260:CP977 RS30670
gene id: 67260:CP977_RS30670
uniprot id: A0A5J6IWK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

67260:CP977 RS09510
gene id: 67260:CP977_RS09510
uniprot id: A0A5J6IV43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

67260:CP977 RS21005
gene id: 67260:CP977_RS21005
uniprot id: A0A5J6IRX3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS09325
gene id: 67260:CP977_RS09325
uniprot id: A0A5J6IMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

67260:CP977 RS27930
gene id: 67260:CP977_RS27930
uniprot id: A0A5J6IVB0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

67260:CP977 RS23040
gene id: 67260:CP977_RS23040
uniprot id: A0A5J6J0S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

67260:CP977 RS31530
gene id: 67260:CP977_RS31530
uniprot id: A0A5J6J4Y2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS03365
gene id: 67260:CP977_RS03365
uniprot id: A0A5J6IKA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS24920
gene id: 67260:CP977_RS24920
uniprot id: A0A5J6J1N2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

67260:CP977 RS32650
gene id: 67260:CP977_RS32650
uniprot id: A0A5J6J1Q0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

67260:CP977 RS05500
gene id: 67260:CP977_RS05500
uniprot id: A0A5J6IYC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

67260:CP977 RS14150
gene id: 67260:CP977_RS14150
uniprot id: A0A5J6ILB7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

67260:CP977 RS13610
gene id: 67260:CP977_RS13610
uniprot id: A0A5J6IW62
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

67260:CP977 RS07295
gene id: 67260:CP977_RS07295
uniprot id: A0A5J6IIB7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

67260:CP977 RS26185
gene id: 67260:CP977_RS26185
uniprot id: A0A5J6IS17
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

67260:CP977 RS08305
gene id: 67260:CP977_RS08305
uniprot id: A0A5J6ILC3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67260:CP977 RS14085
gene id: 67260:CP977_RS14085
uniprot id: A0A5J6IXD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

67260:CP977 RS06380
gene id: 67260:CP977_RS06380
uniprot id: A0A5J6IL03
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

67260:CP977 RS14400
gene id: 67260:CP977_RS14400
uniprot id: A0A5J6IZG5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

67260:CP977 RS24065
gene id: 67260:CP977_RS24065
uniprot id: A0A5J6IX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS09585
gene id: 67260:CP977_RS09585
uniprot id: A0A5J6INJ9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

67260:CP977 RS16540
gene id: 67260:CP977_RS16540
uniprot id: A0A5J6IPP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS31335
gene id: 67260:CP977_RS31335
uniprot id: A0A5J6IXU9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS09920
gene id: 67260:CP977_RS09920
uniprot id: A0A5J6IVC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

67260:CP977 RS23750
gene id: 67260:CP977_RS23750
uniprot id: A0A5J6IWY1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

67260:CP977 RS06055
gene id: 67260:CP977_RS06055
uniprot id: A0A5J6IN07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

67260:CP977 RS03665
gene id: 67260:CP977_RS03665
uniprot id: A0A5J6IJR5
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS01770
gene id: 67260:CP977_RS01770
uniprot id: A0A5J6IR04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Secreted

67260:CP977 RS31720
gene id: 67260:CP977_RS31720
uniprot id: A0A5J6J5N1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS25425
gene id: 67260:CP977_RS25425
uniprot id: A0A5J6IS81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

67260:CP977 RS17700
gene id: 67260:CP977_RS17700
uniprot id: A0A5J6INK3
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS25895
gene id: 67260:CP977_RS25895
uniprot id: A0A5J6IXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

67260:CP977 RS31725
gene id: 67260:CP977_RS31725
uniprot id: A0A5J6IV81
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS12720
gene id: 67260:CP977_RS12720
uniprot id: A0A5J6IKW7
names: Subcellular Location Annotation
messages: cell wall

67260:CP977 RS31420
gene id: 67260:CP977_RS31420
uniprot id: A0A5J6IUJ4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67260:CP977 RS20185
gene id: 67260:CP977_RS20185
uniprot id: A0A5J6IPP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67260:CP977 RS15040
gene id: 67260:CP977_RS15040
uniprot id: A0A5J6IWV0
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS06620
gene id: 67260:CP977_RS06620
uniprot id: A0A5J6IHM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

67260:CP977 RS12935
gene id: 67260:CP977_RS12935
uniprot id: A0A5J6IQ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

67260:CP977 RS27560
gene id: 67260:CP977_RS27560
uniprot id: A0A5J6IV41
names: Similarity
messages: Belongs to the catalase family.

67260:CP977 RS15765
gene id: 67260:CP977_RS15765
uniprot id: A0A5J6IQI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

67260:CP977 RS06195
gene id: 67260:CP977_RS06195
uniprot id: A0A5J6ITB0
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS05060
gene id: 67260:CP977_RS05060
uniprot id: A0A5J6ISS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS24125
gene id: 67260:CP977_RS24125
uniprot id: A0A5J6IVX6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

67260:CP977 RS18205
gene id: 67260:CP977_RS18205
uniprot id: A0A5J6IUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS32210
gene id: 67260:CP977_RS32210
uniprot id: A0A5J6J1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

67260:CP977 RS05965
gene id: 67260:CP977_RS05965
uniprot id: A0A5J6IHT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

67260:CP977 RS08690
gene id: 67260:CP977_RS08690
uniprot id: A0A5J6IUI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

67260:CP977 RS31130
gene id: 67260:CP977_RS31130
uniprot id: A0A5J6IUY5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS21455
gene id: 67260:CP977_RS21455
uniprot id: A0A5J6IS49
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS20150
gene id: 67260:CP977_RS20150
uniprot id: A0A5J6ISK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

67260:CP977 RS15855
gene id: 67260:CP977_RS15855
uniprot id: A0A5J6IX82
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS24670
gene id: 67260:CP977_RS24670
uniprot id: A0A5J6IRU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

67260:CP977 RS08185
gene id: 67260:CP977_RS08185
uniprot id: A0A5J6ILA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS12340
gene id: 67260:CP977_RS12340
uniprot id: A0A5J6IWG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS24345
gene id: 67260:CP977_RS24345
uniprot id: A0A5J6ITC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

67260:CP977 RS20895
gene id: 67260:CP977_RS20895
uniprot id: A0A5J6IRV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

67260:CP977 RS24405
gene id: 67260:CP977_RS24405
uniprot id: A0A5J6IX87
names: Cofactor
messages: Binds 1 FAD per subunit.

67260:CP977 RS07925
gene id: 67260:CP977_RS07925
uniprot id: A0A5J6IIM2
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

67260:CP977 RS12200
gene id: 67260:CP977_RS12200
uniprot id: A0A5J6IPW6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS14295
gene id: 67260:CP977_RS14295
uniprot id: A0A5J6INY1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS24935
gene id: 67260:CP977_RS24935
uniprot id: A0A5J6IRZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

67260:CP977 RS20730
gene id: 67260:CP977_RS20730
uniprot id: A0A5J6IVF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

67260:CP977 RS06530
gene id: 67260:CP977_RS06530
uniprot id: A0A5J6J0R4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS19640
gene id: 67260:CP977_RS19640
uniprot id: A0A5J6IPG4
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS32140
gene id: 67260:CP977_RS32140
uniprot id: A0A5J6IXW0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS09155
gene id: 67260:CP977_RS09155
uniprot id: A0A5J6IMF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

67260:CP977 RS21050
gene id: 67260:CP977_RS21050
uniprot id: A0A5J6IU74
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS11340
gene id: 67260:CP977_RS11340
uniprot id: A0A5J6IR43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS13200
gene id: 67260:CP977_RS13200
uniprot id: A0A5J6IWZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS08635
gene id: 67260:CP977_RS08635
uniprot id: A0A5J6IJ28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

67260:CP977 RS06965
gene id: 67260:CP977_RS06965
uniprot id: A0A5J6IIA6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

67260:CP977 RS09370
gene id: 67260:CP977_RS09370
uniprot id: A0A5J6INF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

67260:CP977 RS14310
gene id: 67260:CP977_RS14310
uniprot id: A0A5J6IXH4
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS33020
gene id: 67260:CP977_RS33020
uniprot id: A0A5J6J679
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS25780
gene id: 67260:CP977_RS25780
uniprot id: A0A5J6IV66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

67260:CP977 RS23055
gene id: 67260:CP977_RS23055
uniprot id: A0A5J6IR39
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

67260:CP977 RS03275
gene id: 67260:CP977_RS03275
uniprot id: A0A5J6IRQ2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

67260:CP977 RS27735
gene id: 67260:CP977_RS27735
uniprot id: A0A5J6J3W1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS20540
gene id: 67260:CP977_RS20540
uniprot id: A0A5J6IPU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

67260:CP977 RS09330
gene id: 67260:CP977_RS09330
uniprot id: A0A5J6ILD1
names: Similarity
messages: Belongs to the YggT family.

67260:CP977 RS27335
gene id: 67260:CP977_RS27335
uniprot id: A0A5J6IT81
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

67260:CP977 RS25210
gene id: 67260:CP977_RS25210
uniprot id: A0A5J6IS45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

67260:CP977 RS22420
gene id: 67260:CP977_RS22420
uniprot id: A0A5J6J0F9
names: Similarity
messages: Belongs to the peptidase S8 family.

67260:CP977 RS20705
gene id: 67260:CP977_RS20705
uniprot id: A0A5J6IPX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

67260:CP977 RS27680
gene id: 67260:CP977_RS27680
uniprot id: A0A5J6ISR8
names: Subunit
messages: Homotetramer.

67260:CP977 RS09985
gene id: 67260:CP977_RS09985
uniprot id: A0A5J6INR6
names: Similarity
messages: Belongs to the glutamine synthetase family.

67260:CP977 RS22690
gene id: 67260:CP977_RS22690
uniprot id: A0A5J6IWE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

67260:CP977 RS06425
gene id: 67260:CP977_RS06425
uniprot id: A0A5J6ILW1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

67260:CP977 RS18225
gene id: 67260:CP977_RS18225
uniprot id: A0A5J6IZR6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

67260:CP977 RS24730
gene id: 67260:CP977_RS24730
uniprot id: A0A5J6IW82
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

67260:CP977 RS22025
gene id: 67260:CP977_RS22025
uniprot id: A0A5J6IQX9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS28310
gene id: 67260:CP977_RS28310
uniprot id: A0A5J6IVN3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS24135
gene id: 67260:CP977_RS24135
uniprot id: A0A5J6IT90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

67260:CP977 RS11105
gene id: 67260:CP977_RS11105
uniprot id: A0A5J6IM49
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

67260:CP977 RS09550
gene id: 67260:CP977_RS09550
uniprot id: A0A5J6ILV1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

67260:CP977 RS17880
gene id: 67260:CP977_RS17880
uniprot id: A0A5J6IRK5
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS06690
gene id: 67260:CP977_RS06690
uniprot id: A0A5J6ITL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67260:CP977 RS06870
gene id: 67260:CP977_RS06870
uniprot id: A0A5J6IKP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

67260:CP977 RS03175
gene id: 67260:CP977_RS03175
uniprot id: A0A5J6IK75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

67260:CP977 RS10855
gene id: 67260:CP977_RS10855
uniprot id: A0A5J6IK56
names: Similarity
messages: Belongs to the CdaR family.

67260:CP977 RS18780
gene id: 67260:CP977_RS18780
uniprot id: A0A5J6IZX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

67260:CP977 RS27985
gene id: 67260:CP977_RS27985
uniprot id: A0A5J6IVC0
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

67260:CP977 RS22430
gene id: 67260:CP977_RS22430
uniprot id: A0A5J6J1I5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

67260:CP977 RS14090
gene id: 67260:CP977_RS14090
uniprot id: A0A5J6ILI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

67260:CP977 RS13080
gene id: 67260:CP977_RS13080
uniprot id: A0A5J6IWX4
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS13170
gene id: 67260:CP977_RS13170
uniprot id: A0A5J6IP80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS05590
gene id: 67260:CP977_RS05590
uniprot id: A0A5J6IME4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

67260:CP977 RS09700
gene id: 67260:CP977_RS09700
uniprot id: A0A5J6IMP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

67260:CP977 RS16640
gene id: 67260:CP977_RS16640
uniprot id: A0A5J6IMZ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS24285
gene id: 67260:CP977_RS24285
uniprot id: A0A5J6J010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

67260:CP977 RS28595
gene id: 67260:CP977_RS28595
uniprot id: A0A5J6J4B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

67260:CP977 RS18415
gene id: 67260:CP977_RS18415
uniprot id: A0A5J6IYH0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

67260:CP977 RS18450
gene id: 67260:CP977_RS18450
uniprot id: A0A5J6IQJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

67260:CP977 RS17690
gene id: 67260:CP977_RS17690
uniprot id: A0A5J6IZF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

67260:CP977 RS23830
gene id: 67260:CP977_RS23830
uniprot id: A0A5J6J152
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

67260:CP977 RS05045
gene id: 67260:CP977_RS05045
uniprot id: A0A5J6IJV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

67260:CP977 RS08295
gene id: 67260:CP977_RS08295
uniprot id: A0A5J6IKU1
names: Similarity
messages: Belongs to the asp23 family.

67260:CP977 RS08320
gene id: 67260:CP977_RS08320
uniprot id: A0A5J6IIG9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS13215
gene id: 67260:CP977_RS13215
uniprot id: A0A5J6IQA8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

67260:CP977 RS24495
gene id: 67260:CP977_RS24495
uniprot id: A0A5J6IZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

67260:CP977 RS13035
gene id: 67260:CP977_RS13035
uniprot id: A0A5J6IL72
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS07055
gene id: 67260:CP977_RS07055
uniprot id: A0A5J6IKR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

67260:CP977 RS13995
gene id: 67260:CP977_RS13995
uniprot id: A0A5J6ISC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

67260:CP977 RS20075
gene id: 67260:CP977_RS20075
uniprot id: A0A5J6IPN0
names: Function
names: Similarity
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

67260:CP977 RS19560
gene id: 67260:CP977_RS19560
uniprot id: A0A5J6IZ55
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

67260:CP977 RS21715
gene id: 67260:CP977_RS21715
uniprot id: A0A5J6IUQ1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

67260:CP977 RS21665
gene id: 67260:CP977_RS21665
uniprot id: A0A5J6IS90
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.
messages: Cytoplasm

67260:CP977 RS29570
gene id: 67260:CP977_RS29570
uniprot id: A0A5J6J4T1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

67260:CP977 RS23530
gene id: 67260:CP977_RS23530
uniprot id: A0A5J6J217
names: Similarity
messages: Belongs to the peptidase C40 family.

67260:CP977 RS17580
gene id: 67260:CP977_RS17580
uniprot id: A0A5J6IY32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

67260:CP977 RS32065
gene id: 67260:CP977_RS32065
uniprot id: A0A5J6IVD1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS14080
gene id: 67260:CP977_RS14080
uniprot id: A0A5J6ILA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

67260:CP977 RS26075
gene id: 67260:CP977_RS26075
uniprot id: A0A5J6J273
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

67260:CP977 RS20275
gene id: 67260:CP977_RS20275
uniprot id: A0A5J6IZH3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

67260:CP977 RS20655
gene id: 67260:CP977_RS20655
uniprot id: A0A5J6IQ53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

67260:CP977 RS21630
gene id: 67260:CP977_RS21630
uniprot id: A0A5J6IPN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

67260:CP977 RS24375
gene id: 67260:CP977_RS24375
uniprot id: A0A5J6IRQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS11645
gene id: 67260:CP977_RS11645
uniprot id: A0A5J6J333
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

67260:CP977 RS19095
gene id: 67260:CP977_RS19095
uniprot id: A0A5J6IS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

67260:CP977 RS28845
gene id: 67260:CP977_RS28845
uniprot id: A0A5J6IWR2
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS10205
gene id: 67260:CP977_RS10205
uniprot id: A0A5J6ILS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS21605
gene id: 67260:CP977_RS21605
uniprot id: A0A5J6IT87
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

67260:CP977 RS15775
gene id: 67260:CP977_RS15775
uniprot id: A0A5J6IPB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS13060
gene id: 67260:CP977_RS13060
uniprot id: A0A5J6IRW6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

67260:CP977 RS16910
gene id: 67260:CP977_RS16910
uniprot id: A0A5J6IPV4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

67260:CP977 RS24695
gene id: 67260:CP977_RS24695
uniprot id: A0A5J6IXC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

67260:CP977 RS03750
gene id: 67260:CP977_RS03750
uniprot id: A0A5J6J0K8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

67260:CP977 RS08675
gene id: 67260:CP977_RS08675
uniprot id: A0A5J6ILI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

67260:CP977 RS09070
gene id: 67260:CP977_RS09070
uniprot id: A0A5J6ILP9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS04410
gene id: 67260:CP977_RS04410
uniprot id: A0A5J6ISA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS11245
gene id: 67260:CP977_RS11245
uniprot id: A0A5J6IW17
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

67260:CP977 RS06985
gene id: 67260:CP977_RS06985
uniprot id: A0A5J6ILA5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

67260:CP977 RS24055
gene id: 67260:CP977_RS24055
uniprot id: A0A5J6IUD2
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS11875
gene id: 67260:CP977_RS11875
uniprot id: A0A5J6IMW8
names: Similarity
messages: Belongs to the allantoicase family.

67260:CP977 RS20810
gene id: 67260:CP977_RS20810
uniprot id: A0A5J6IPY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS15120
gene id: 67260:CP977_RS15120
uniprot id: A0A5J6IXW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

67260:CP977 RS27900
gene id: 67260:CP977_RS27900
uniprot id: A0A5J6ITR7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67260:CP977 RS23820
gene id: 67260:CP977_RS23820
uniprot id: A0A5J6IWY8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

67260:CP977 RS13510
gene id: 67260:CP977_RS13510
uniprot id: A0A5J6IL07
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

67260:CP977 RS08585
gene id: 67260:CP977_RS08585
uniprot id: A0A5J6IJ17
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

67260:CP977 RS07390
gene id: 67260:CP977_RS07390
uniprot id: A0A5J6II10
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67260:CP977 RS24435
gene id: 67260:CP977_RS24435
uniprot id: A0A5J6IS25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS27600
gene id: 67260:CP977_RS27600
uniprot id: A0A5J6IXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

67260:CP977 RS20650
gene id: 67260:CP977_RS20650
uniprot id: A0A5J6IPW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

67260:CP977 RS22835
gene id: 67260:CP977_RS22835
uniprot id: A0A5J6IXH7
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS08685
gene id: 67260:CP977_RS08685
uniprot id: A0A5J6IIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

67260:CP977 RS25205
gene id: 67260:CP977_RS25205
uniprot id: A0A5J6J2Q4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS26615
gene id: 67260:CP977_RS26615
uniprot id: A0A5J6IX52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS25345
gene id: 67260:CP977_RS25345
uniprot id: A0A5J6ITT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

67260:CP977 RS26290
gene id: 67260:CP977_RS26290
uniprot id: A0A5J6IUG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

67260:CP977 RS10865
gene id: 67260:CP977_RS10865
uniprot id: A0A5J6IN80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

67260:CP977 RS24635
gene id: 67260:CP977_RS24635
uniprot id: A0A5J6IUL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

67260:CP977 RS05915
gene id: 67260:CP977_RS05915
uniprot id: A0A5J6IKS2
names: Similarity
messages: Belongs to the UPF0749 family.

67260:CP977 RS25170
gene id: 67260:CP977_RS25170
uniprot id: A0A5J6ITQ6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

67260:CP977 RS04220
gene id: 67260:CP977_RS04220
uniprot id: A0A5J6IGE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

67260:CP977 RS21465
gene id: 67260:CP977_RS21465
uniprot id: A0A5J6IS76
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

67260:CP977 RS30705
gene id: 67260:CP977_RS30705
uniprot id: A0A5J6IYZ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

67260:CP977 RS01375
gene id: 67260:CP977_RS01375
uniprot id: A0A5J6IJH3
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS13470
gene id: 67260:CP977_RS13470
uniprot id: A0A5J6IL77
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

67260:CP977 RS13460
gene id: 67260:CP977_RS13460
uniprot id: A0A5J6IKZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

67260:CP977 RS08180
gene id: 67260:CP977_RS08180
uniprot id: A0A5J6IPF5
names: Similarity
messages: Belongs to the peptidase U62 family.

67260:CP977 RS13210
gene id: 67260:CP977_RS13210
uniprot id: A0A5J6ILA0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

67260:CP977 RS14410
gene id: 67260:CP977_RS14410
uniprot id: A0A5J6INN4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

67260:CP977 RS09290
gene id: 67260:CP977_RS09290
uniprot id: A0A5J6IU79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

67260:CP977 RS19125
gene id: 67260:CP977_RS19125
uniprot id: A0A5J6J023
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

67260:CP977 RS20190
gene id: 67260:CP977_RS20190
uniprot id: A0A5J6IPX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67260:CP977 RS29405
gene id: 67260:CP977_RS29405
uniprot id: A0A5J6IUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

67260:CP977 RS29145
gene id: 67260:CP977_RS29145
uniprot id: A0A5J6IW22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

67260:CP977 RS28390
gene id: 67260:CP977_RS28390
uniprot id: A0A5J6IT30
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

67260:CP977 RS07440
gene id: 67260:CP977_RS07440
uniprot id: A0A5J6II23
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS23705
gene id: 67260:CP977_RS23705
uniprot id: A0A5J6IQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

67260:CP977 RS04930
gene id: 67260:CP977_RS04930
uniprot id: A0A5J6IM31
names: Similarity
messages: Belongs to the glutathione peroxidase family.

67260:CP977 RS20180
gene id: 67260:CP977_RS20180
uniprot id: A0A5J6J0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67260:CP977 RS27285
gene id: 67260:CP977_RS27285
uniprot id: A0A5J6ITG8
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

67260:CP977 RS09935
gene id: 67260:CP977_RS09935
uniprot id: A0A5J6INQ6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS15665
gene id: 67260:CP977_RS15665
uniprot id: A0A5J6IT28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67260:CP977 RS06325
gene id: 67260:CP977_RS06325
uniprot id: A0A5J6ILQ0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

67260:CP977 RS20195
gene id: 67260:CP977_RS20195
uniprot id: A0A5J6ITT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

67260:CP977 RS09135
gene id: 67260:CP977_RS09135
uniprot id: A0A5J6IUX2
names: Similarity
messages: Belongs to the TrpC family.

67260:CP977 RS26635
gene id: 67260:CP977_RS26635
uniprot id: A0A5J6IUP2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

67260:CP977 RS31830
gene id: 67260:CP977_RS31830
uniprot id: A0A5J6J5Q0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67260:CP977 RS02210
gene id: 67260:CP977_RS02210
uniprot id: A0A5J6IKJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

67260:CP977 RS33620
gene id: 67260:CP977_RS33620
uniprot id: A0A5J6J494
names: Similarity
messages: Belongs to the peptidase S1 family.

67260:CP977 RS10145
gene id: 67260:CP977_RS10145
uniprot id: A0A5J6IMW4
names: Similarity
messages: Belongs to the glutamine synthetase family.

67260:CP977 RS27570
gene id: 67260:CP977_RS27570
uniprot id: A0A5J6ISQ0
names: Similarity
messages: Belongs to the hyi family.

67260:CP977 RS31545
gene id: 67260:CP977_RS31545
uniprot id: A0A5J6IV50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS20620
gene id: 67260:CP977_RS20620
uniprot id: A0A5J6IRP7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

67260:CP977 RS22265
gene id: 67260:CP977_RS22265
uniprot id: A0A5J6IR17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

67260:CP977 RS05240
gene id: 67260:CP977_RS05240
uniprot id: A0A5J6IHG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

67260:CP977 RS04345
gene id: 67260:CP977_RS04345
uniprot id: A0A5J6IRK2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

67260:CP977 RS08210
gene id: 67260:CP977_RS08210
uniprot id: A0A5J6IIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

67260:CP977 RS25420
gene id: 67260:CP977_RS25420
uniprot id: A0A5J6J2T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

67260:CP977 RS05065
gene id: 67260:CP977_RS05065
uniprot id: A0A5J6IHD3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

67260:CP977 RS17540
gene id: 67260:CP977_RS17540
uniprot id: A0A5J6IN68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

67260:CP977 RS29725
gene id: 67260:CP977_RS29725
uniprot id: A0A5J6IW64
names: Similarity
messages: Belongs to the ribulokinase family.

67260:CP977 RS28050
gene id: 67260:CP977_RS28050
uniprot id: A0A5J6J415
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

67260:CP977 RS12455
gene id: 67260:CP977_RS12455
uniprot id: A0A5J6IMR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS10990
gene id: 67260:CP977_RS10990
uniprot id: A0A5J6IMI9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

67260:CP977 RS16025
gene id: 67260:CP977_RS16025
uniprot id: A0A5J6IXB0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS21335
gene id: 67260:CP977_RS21335
uniprot id: A0A5J6IQ69
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

67260:CP977 RS17410
gene id: 67260:CP977_RS17410
uniprot id: A0A5J6IMT6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS03335
gene id: 67260:CP977_RS03335
uniprot id: A0A5J6IR34
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS06885
gene id: 67260:CP977_RS06885
uniprot id: A0A5J6ITP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

67260:CP977 RS23105
gene id: 67260:CP977_RS23105
uniprot id: A0A5J6J1V0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

67260:CP977 RS14145
gene id: 67260:CP977_RS14145
uniprot id: A0A5J6IWF0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

67260:CP977 RS01855
gene id: 67260:CP977_RS01855
uniprot id: A0A5J6IJM2
names: Similarity
messages: Belongs to the peptidase S11 family.

67260:CP977 RS02555
gene id: 67260:CP977_RS02555
uniprot id: A0A5J6IIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

67260:CP977 RS12610
gene id: 67260:CP977_RS12610
uniprot id: A0A5J6IL05
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS09340
gene id: 67260:CP977_RS09340
uniprot id: A0A5J6ILT1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

67260:CP977 RS20590
gene id: 67260:CP977_RS20590
uniprot id: A0A5J6J0P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm

67260:CP977 RS11285
gene id: 67260:CP977_RS11285
uniprot id: A0A5J6IV53
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

67260:CP977 RS08260
gene id: 67260:CP977_RS08260
uniprot id: A0A5J6ITS6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS06555
gene id: 67260:CP977_RS06555
uniprot id: A0A5J6INA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

67260:CP977 RS28860
gene id: 67260:CP977_RS28860
uniprot id: A0A5J6IVR8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

67260:CP977 RS22865
gene id: 67260:CP977_RS22865
uniprot id: A0A5J6IWH5
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS13775
gene id: 67260:CP977_RS13775
uniprot id: A0A5J6IL55
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

67260:CP977 RS04760
gene id: 67260:CP977_RS04760
uniprot id: A0A5J6IGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

67260:CP977 RS25140
gene id: 67260:CP977_RS25140
uniprot id: A0A5J6J2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS13280
gene id: 67260:CP977_RS13280
uniprot id: A0A5J6ILB0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

67260:CP977 RS25255
gene id: 67260:CP977_RS25255
uniprot id: A0A5J6J2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

67260:CP977 RS11295
gene id: 67260:CP977_RS11295
uniprot id: A0A5J6IWC6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

67260:CP977 RS07445
gene id: 67260:CP977_RS07445
uniprot id: A0A5J6J2U8
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS17625
gene id: 67260:CP977_RS17625
uniprot id: A0A5J6IQI6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS23645
gene id: 67260:CP977_RS23645
uniprot id: A0A5J6J132
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

67260:CP977 RS30445
gene id: 67260:CP977_RS30445
uniprot id: A0A5J6IU45
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

67260:CP977 RS09190
gene id: 67260:CP977_RS09190
uniprot id: A0A5J6IJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

67260:CP977 RS07155
gene id: 67260:CP977_RS07155
uniprot id: A0A5J6IKA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

67260:CP977 RS16320
gene id: 67260:CP977_RS16320
uniprot id: A0A5J6IPL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

67260:CP977 RS23265
gene id: 67260:CP977_RS23265
uniprot id: A0A5J6J0W1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

67260:CP977 RS18930
gene id: 67260:CP977_RS18930
uniprot id: A0A5J6IYN4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

67260:CP977 RS23690
gene id: 67260:CP977_RS23690
uniprot id: A0A5J6IWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

67260:CP977 RS13815
gene id: 67260:CP977_RS13815
uniprot id: A0A5J6INE2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

67260:CP977 RS06565
gene id: 67260:CP977_RS06565
uniprot id: A0A5J6IT02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

67260:CP977 RS20980
gene id: 67260:CP977_RS20980
uniprot id: A0A5J6J0V2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

67260:CP977 RS10245
gene id: 67260:CP977_RS10245
uniprot id: A0A5J6IJW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

67260:CP977 RS33610
gene id: 67260:CP977_RS33610
uniprot id: A0A5J6IVJ9
names: Similarity
messages: Belongs to the peptidase S51 family.

67260:CP977 RS15965
gene id: 67260:CP977_RS15965
uniprot id: A0A5J6IPM6
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS09205
gene id: 67260:CP977_RS09205
uniprot id: A0A5J6IMG7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

67260:CP977 RS18825
gene id: 67260:CP977_RS18825
uniprot id: A0A5J6IYL8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

67260:CP977 RS18805
gene id: 67260:CP977_RS18805
uniprot id: A0A5J6IRZ0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

67260:CP977 RS03170
gene id: 67260:CP977_RS03170
uniprot id: A0A5J6IGA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

67260:CP977 RS32815
gene id: 67260:CP977_RS32815
uniprot id: A0A5J6IVR7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

67260:CP977 RS08885
gene id: 67260:CP977_RS08885
uniprot id: A0A5J6IMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

67260:CP977 RS29345
gene id: 67260:CP977_RS29345
uniprot id: A0A5J6IWY7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS15450
gene id: 67260:CP977_RS15450
uniprot id: A0A5J6IX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS22165
gene id: 67260:CP977_RS22165
uniprot id: A0A5J6ISI3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

67260:CP977 RS22490
gene id: 67260:CP977_RS22490
uniprot id: A0A5J6IR48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS22120
gene id: 67260:CP977_RS22120
uniprot id: A0A5J6IPV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS32500
gene id: 67260:CP977_RS32500
uniprot id: A0A5J6J5H5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

67260:CP977 RS23710
gene id: 67260:CP977_RS23710
uniprot id: A0A5J6J246
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

67260:CP977 RS28710
gene id: 67260:CP977_RS28710
uniprot id: A0A5J6IT85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

67260:CP977 RS15505
gene id: 67260:CP977_RS15505
uniprot id: A0A5J6IPE0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

67260:CP977 RS08705
gene id: 67260:CP977_RS08705
uniprot id: A0A5J6IN34
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

67260:CP977 RS08710
gene id: 67260:CP977_RS08710
uniprot id: A0A5J6IM83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

67260:CP977 RS20710
gene id: 67260:CP977_RS20710
uniprot id: A0A5J6IQ62
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

67260:CP977 RS11130
gene id: 67260:CP977_RS11130
uniprot id: A0A5J6IJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

67260:CP977 RS25540
gene id: 67260:CP977_RS25540
uniprot id: A0A5J6J1Z2
names: Similarity
messages: Belongs to the Dps family.

67260:CP977 RS17645
gene id: 67260:CP977_RS17645
uniprot id: A0A5J6IN93
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

67260:CP977 RS16340
gene id: 67260:CP977_RS16340
uniprot id: A0A5J6IPR9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

67260:CP977 RS23515
gene id: 67260:CP977_RS23515
uniprot id: A0A5J6IZY8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

67260:CP977 RS27095
gene id: 67260:CP977_RS27095
uniprot id: A0A5J6ISG8
names: Similarity
messages: Belongs to the CdaR family.

67260:CP977 RS09400
gene id: 67260:CP977_RS09400
uniprot id: A0A5J6IJ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

67260:CP977 RS21450
gene id: 67260:CP977_RS21450
uniprot id: A0A5J6IT58
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS09200
gene id: 67260:CP977_RS09200
uniprot id: A0A5J6INC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

67260:CP977 RS10185
gene id: 67260:CP977_RS10185
uniprot id: A0A5J6IJT7
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS20740
gene id: 67260:CP977_RS20740
uniprot id: A0A5J6IZP6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

67260:CP977 RS21485
gene id: 67260:CP977_RS21485
uniprot id: A0A5J6J135
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

67260:CP977 RS10925
gene id: 67260:CP977_RS10925
uniprot id: A0A5J6IN92
names: Similarity
messages: Belongs to the OsmC/Ohr family.

67260:CP977 RS06900
gene id: 67260:CP977_RS06900
uniprot id: A0A5J6IM35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

67260:CP977 RS31500
gene id: 67260:CP977_RS31500
uniprot id: A0A5J6IVF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

67260:CP977 RS01260
gene id: 67260:CP977_RS01260
uniprot id: A0A5J6IQB9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS27590
gene id: 67260:CP977_RS27590
uniprot id: A0A5J6ITC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

67260:CP977 RS09350
gene id: 67260:CP977_RS09350
uniprot id: A0A5J6IIZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

67260:CP977 RS23675
gene id: 67260:CP977_RS23675
uniprot id: A0A5J6J7E9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS29315
gene id: 67260:CP977_RS29315
uniprot id: A0A5J6J3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS12215
gene id: 67260:CP977_RS12215
uniprot id: A0A5J6IRI2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

67260:CP977 RS01560
gene id: 67260:CP977_RS01560
uniprot id: A0A5J6IHJ6
names: Subcellular Location Annotation
messages: Cytoplasm

67260:CP977 RS06410
gene id: 67260:CP977_RS06410
uniprot id: A0A5J6ITF6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

67260:CP977 RS09120
gene id: 67260:CP977_RS09120
uniprot id: A0A5J6ILQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

67260:CP977 RS09520
gene id: 67260:CP977_RS09520
uniprot id: A0A5J6IJI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

67260:CP977 RS12315
gene id: 67260:CP977_RS12315
uniprot id: A0A5J6IKV3
names: Similarity
messages: Belongs to the HypE family.

67260:CP977 RS25125
gene id: 67260:CP977_RS25125
uniprot id: A0A5J6IU09
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS27795
gene id: 67260:CP977_RS27795
uniprot id: A0A5J6ITQ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

67260:CP977 RS29370
gene id: 67260:CP977_RS29370
uniprot id: A0A5J6J3Y8
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS26865
gene id: 67260:CP977_RS26865
uniprot id: A0A5J6IYG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

67260:CP977 RS21730
gene id: 67260:CP977_RS21730
uniprot id: A0A5J6IVY1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

67260:CP977 RS20135
gene id: 67260:CP977_RS20135
uniprot id: A0A5J6IPP0
names: Subcellular Location Annotation
messages: Cytoplasm

67260:CP977 RS02295
gene id: 67260:CP977_RS02295
uniprot id: A0A5J6IR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

67260:CP977 RS17135
gene id: 67260:CP977_RS17135
uniprot id: A0A5J6IXU7
names: Similarity
messages: Belongs to the peptidase M18 family.

67260:CP977 RS20565
gene id: 67260:CP977_RS20565
uniprot id: A0A5J6IRN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

67260:CP977 RS16890
gene id: 67260:CP977_RS16890
uniprot id: A0A5J6IN42
names: Similarity
messages: Belongs to the CobH/CbiC family.

67260:CP977 RS12465
gene id: 67260:CP977_RS12465
uniprot id: A0A5J6IN55
names: Similarity
messages: Belongs to the group II decarboxylase family.

67260:CP977 RS20865
gene id: 67260:CP977_RS20865
uniprot id: A0A5J6IPZ3
names: Similarity
messages: Belongs to the YciI family.

67260:CP977 RS16520
gene id: 67260:CP977_RS16520
uniprot id: A0A5J6IMQ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS19865
gene id: 67260:CP977_RS19865
uniprot id: A0A5J6ISG2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

67260:CP977 RS06185
gene id: 67260:CP977_RS06185
uniprot id: A0A5J6IHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

67260:CP977 RS12020
gene id: 67260:CP977_RS12020
uniprot id: A0A5J6IKE3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

67260:CP977 RS20690
gene id: 67260:CP977_RS20690
uniprot id: A0A5J6IZN5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

67260:CP977 RS20780
gene id: 67260:CP977_RS20780
uniprot id: A0A5J6IVG1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

67260:CP977 RS15735
gene id: 67260:CP977_RS15735
uniprot id: A0A5J6IM16
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

67260:CP977 RS24485
gene id: 67260:CP977_RS24485
uniprot id: A0A5J6IS35
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

67260:CP977 RS08080
gene id: 67260:CP977_RS08080
uniprot id: A0A5J6IL83
names: Similarity
messages: Belongs to the band 7/mec-2 family.

67260:CP977 RS01610
gene id: 67260:CP977_RS01610
uniprot id: A0A5J6IFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

67260:CP977 RS22290
gene id: 67260:CP977_RS22290
uniprot id: A0A5J6IW75
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

67260:CP977 RS22665
gene id: 67260:CP977_RS22665
uniprot id: A0A5J6IQX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

67260:CP977 RS23300
gene id: 67260:CP977_RS23300
uniprot id: A0A5J6IU24
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

67260:CP977 RS14555
gene id: 67260:CP977_RS14555
uniprot id: A0A5J6ILQ5
names: Similarity
messages: Belongs to the asparagine synthetase family.

67260:CP977 RS29730
gene id: 67260:CP977_RS29730
uniprot id: A0A5J6J439
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

67260:CP977 RS10755
gene id: 67260:CP977_RS10755
uniprot id: A0A5J6ILZ1
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS18150
gene id: 67260:CP977_RS18150
uniprot id: A0A5J6IUA0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

67260:CP977 RS10620
gene id: 67260:CP977_RS10620
uniprot id: A0A5J6J314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS30585
gene id: 67260:CP977_RS30585
uniprot id: A0A5J6IUP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS03165
gene id: 67260:CP977_RS03165
uniprot id: A0A5J6IGH8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS28425
gene id: 67260:CP977_RS28425
uniprot id: A0A5J6IWJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS05620
gene id: 67260:CP977_RS05620
uniprot id: A0A5J6IHH5
names: Similarity
messages: Belongs to the cytochrome P450 family.

67260:CP977 RS20725
gene id: 67260:CP977_RS20725
uniprot id: A0A5J6IRR7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

67260:CP977 RS08400
gene id: 67260:CP977_RS08400
uniprot id: A0A5J6IKW4
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

67260:CP977 RS20035
gene id: 67260:CP977_RS20035
uniprot id: A0A5J6IRF2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS06210
gene id: 67260:CP977_RS06210
uniprot id: A0A5J6ILM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

67260:CP977 RS08530
gene id: 67260:CP977_RS08530
uniprot id: A0A5J6IIW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

67260:CP977 RS26395
gene id: 67260:CP977_RS26395
uniprot id: A0A5J6IT13
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS17745
gene id: 67260:CP977_RS17745
uniprot id: A0A5J6IYY6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

67260:CP977 RS03215
gene id: 67260:CP977_RS03215
uniprot id: A0A5J6IGI8
names: Similarity
messages: Belongs to the XFP family.

67260:CP977 RS23110
gene id: 67260:CP977_RS23110
uniprot id: A0A5J6IR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

67260:CP977 RS02365
gene id: 67260:CP977_RS02365
uniprot id: A0A5J6IJU9
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS09865
gene id: 67260:CP977_RS09865
uniprot id: A0A5J6INP4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

67260:CP977 RS32225
gene id: 67260:CP977_RS32225
uniprot id: A0A5J6J5D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

67260:CP977 RS24885
gene id: 67260:CP977_RS24885
uniprot id: A0A5J6IRY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

67260:CP977 RS09375
gene id: 67260:CP977_RS09375
uniprot id: A0A5J6IMJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

67260:CP977 RS09030
gene id: 67260:CP977_RS09030
uniprot id: A0A5J6IIU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

67260:CP977 RS15510
gene id: 67260:CP977_RS15510
uniprot id: A0A5J6IX23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

67260:CP977 RS18100
gene id: 67260:CP977_RS18100
uniprot id: A0A5J6IN56
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS20645
gene id: 67260:CP977_RS20645
uniprot id: A0A5J6J0Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

67260:CP977 RS14125
gene id: 67260:CP977_RS14125
uniprot id: A0A5J6INI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

67260:CP977 RS17245
gene id: 67260:CP977_RS17245
uniprot id: A0A5J6IXW9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

67260:CP977 RS02910
gene id: 67260:CP977_RS02910
uniprot id: A0A5J6IQX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

67260:CP977 RS27915
gene id: 67260:CP977_RS27915
uniprot id: A0A5J6IVF7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

67260:CP977 RS20745
gene id: 67260:CP977_RS20745
uniprot id: A0A5J6IP95
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

67260:CP977 RS20525
gene id: 67260:CP977_RS20525
uniprot id: A0A5J6IP62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

67260:CP977 RS05935
gene id: 67260:CP977_RS05935
uniprot id: A0A5J6ISK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

67260:CP977 RS25370
gene id: 67260:CP977_RS25370
uniprot id: A0A5J6IS71
names: Similarity
messages: Belongs to the WXG100 family.

67260:CP977 RS08000
gene id: 67260:CP977_RS08000
uniprot id: A0A5J6IPC3
names: Similarity
messages: Belongs to the TlyA family.

67260:CP977 RS05165
gene id: 67260:CP977_RS05165
uniprot id: A0A5J6IGX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS29110
gene id: 67260:CP977_RS29110
uniprot id: A0A5J6J3U5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

67260:CP977 RS18010
gene id: 67260:CP977_RS18010
uniprot id: A0A5J6IU85
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

67260:CP977 RS01370
gene id: 67260:CP977_RS01370
uniprot id: A0A5J6IFI3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

67260:CP977 RS11880
gene id: 67260:CP977_RS11880
uniprot id: A0A5J6IVF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

67260:CP977 RS27475
gene id: 67260:CP977_RS27475
uniprot id: A0A5J6IV78
names: Subcellular Location Annotation
messages: Membrane

67260:CP977 RS16435
gene id: 67260:CP977_RS16435
uniprot id: A0A5J6IPN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

67260:CP977 RS18445
gene id: 67260:CP977_RS18445
uniprot id: A0A5J6IRT8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

67260:CP977 RS24170
gene id: 67260:CP977_RS24170
uniprot id: A0A5J6IRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

67260:CP977 RS25785
gene id: 67260:CP977_RS25785
uniprot id: A0A5J6IU07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

67260:CP977 RS20550
gene id: 67260:CP977_RS20550
uniprot id: A0A5J6IQ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

67260:CP977 RS19280
gene id: 67260:CP977_RS19280
uniprot id: A0A5J6INN0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

67260:CP977 RS32470
gene id: 67260:CP977_RS32470
uniprot id: A0A5J6IZR8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

67260:CP977 RS11615
gene id: 67260:CP977_RS11615
uniprot id: A0A5J6INL4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

67260:CP977 RS11820
gene id: 67260:CP977_RS11820
uniprot id: A0A5J6IWD7
names: Similarity
messages: Belongs to the peptidase M1 family.

67260:CP977 RS25145
gene id: 67260:CP977_RS25145
uniprot id: A0A5J6IS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

67260:CP977 RS17685
gene id: 67260:CP977_RS17685
uniprot id: A0A5J6IMY7
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

67260:CP977 RS19625
gene id: 67260:CP977_RS19625
uniprot id: A0A5J6IZ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

67260:CP977 RS22145
gene id: 67260:CP977_RS22145
uniprot id: A0A5J6ITH8
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.