663278:ETHHA RS07230
gene id: 663278:ETHHA_RS07230
uniprot id: E6U703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

663278:ETHHA RS03275
gene id: 663278:ETHHA_RS03275
uniprot id: E6U9V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

663278:ETHHA RS10340
gene id: 663278:ETHHA_RS10340
uniprot id: E6U3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

663278:ETHHA RS10935
gene id: 663278:ETHHA_RS10935
uniprot id: E6U403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

663278:ETHHA RS13500
gene id: 663278:ETHHA_RS13500
uniprot id: E6U7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13170
gene id: 663278:ETHHA_RS13170
uniprot id: E6U735
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

663278:ETHHA RS04640
gene id: 663278:ETHHA_RS04640
uniprot id: E6U3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13935
gene id: 663278:ETHHA_RS13935
uniprot id: E6U8D8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

663278:ETHHA RS00305
gene id: 663278:ETHHA_RS00305
uniprot id: E6U5I2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

663278:ETHHA RS05600
gene id: 663278:ETHHA_RS05600
uniprot id: E6U4M6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

663278:ETHHA RS04555
gene id: 663278:ETHHA_RS04555
uniprot id: E6U3G2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

663278:ETHHA RS01980
gene id: 663278:ETHHA_RS01980
uniprot id: E6U8H9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

663278:ETHHA RS10405
gene id: 663278:ETHHA_RS10405
uniprot id: E6U3J1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

663278:ETHHA RS07430
gene id: 663278:ETHHA_RS07430
uniprot id: E6U7I8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS11490
gene id: 663278:ETHHA_RS11490
uniprot id: E6U4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

663278:ETHHA RS04340
gene id: 663278:ETHHA_RS04340
uniprot id: E6U3C7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

663278:ETHHA RS03170
gene id: 663278:ETHHA_RS03170
uniprot id: E6U9T0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS14260
gene id: 663278:ETHHA_RS14260
uniprot id: E6U8L3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

663278:ETHHA RS04735
gene id: 663278:ETHHA_RS04735
uniprot id: E6U3S1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

663278:ETHHA RS07245
gene id: 663278:ETHHA_RS07245
uniprot id: E6U706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

663278:ETHHA RS05940
gene id: 663278:ETHHA_RS05940
uniprot id: E6U516
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

663278:ETHHA RS04115
gene id: 663278:ETHHA_RS04115
uniprot id: E6U311
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS04435
gene id: 663278:ETHHA_RS04435
uniprot id: E6U3E5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS08760
gene id: 663278:ETHHA_RS08760
uniprot id: E6U9B0
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

663278:ETHHA RS07675
gene id: 663278:ETHHA_RS07675
uniprot id: E6U840
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

663278:ETHHA RS12585
gene id: 663278:ETHHA_RS12585
uniprot id: E6U5Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

663278:ETHHA RS03620
gene id: 663278:ETHHA_RS03620
uniprot id: E6U2J5
names: Caution
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS10365
gene id: 663278:ETHHA_RS10365
uniprot id: E6U3I3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

663278:ETHHA RS07240
gene id: 663278:ETHHA_RS07240
uniprot id: E6U705
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

663278:ETHHA RS06970
gene id: 663278:ETHHA_RS06970
uniprot id: E6U6V0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS01025
gene id: 663278:ETHHA_RS01025
uniprot id: E6U6Q2
names: Similarity
messages: Belongs to the GARS family.

663278:ETHHA RS10055
gene id: 663278:ETHHA_RS10055
uniprot id: E6U350
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

663278:ETHHA RS00140
gene id: 663278:ETHHA_RS00140
uniprot id: E6U5F0
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS12545
gene id: 663278:ETHHA_RS12545
uniprot id: E6U5X3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS08750
gene id: 663278:ETHHA_RS08750
uniprot id: E6U9A6
names: Similarity
messages: Belongs to the DEAD box helicase family.

663278:ETHHA RS01490
gene id: 663278:ETHHA_RS01490
uniprot id: E6U7D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS11670
gene id: 663278:ETHHA_RS11670
uniprot id: E6U4T9
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

663278:ETHHA RS04720
gene id: 663278:ETHHA_RS04720
uniprot id: E6U3R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

663278:ETHHA RS05455
gene id: 663278:ETHHA_RS05455
uniprot id: E6U4J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

663278:ETHHA RS03520
gene id: 663278:ETHHA_RS03520
uniprot id: E6U2H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

663278:ETHHA RS14430
gene id: 663278:ETHHA_RS14430
uniprot id: E6U3H7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

663278:ETHHA RS07625
gene id: 663278:ETHHA_RS07625
uniprot id: E6U7M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS06595
gene id: 663278:ETHHA_RS06595
uniprot id: E6U678
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS00145
gene id: 663278:ETHHA_RS00145
uniprot id: E6U5F1
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

663278:ETHHA RS04380
gene id: 663278:ETHHA_RS04380
uniprot id: E6U3D3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

663278:ETHHA RS12810
gene id: 663278:ETHHA_RS12810
uniprot id: E6U6G6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

663278:ETHHA RS08335
gene id: 663278:ETHHA_RS08335
uniprot id: E6U8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

663278:ETHHA RS10355
gene id: 663278:ETHHA_RS10355
uniprot id: E6U3I1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

663278:ETHHA RS13560
gene id: 663278:ETHHA_RS13560
uniprot id: E6U7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

663278:ETHHA RS08350
gene id: 663278:ETHHA_RS08350
uniprot id: E6U8V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

663278:ETHHA RS13870
gene id: 663278:ETHHA_RS13870
uniprot id: E6U8C6
names: Function
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS00770
gene id: 663278:ETHHA_RS00770
uniprot id: E6U658
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

663278:ETHHA RS13970
gene id: 663278:ETHHA_RS13970
uniprot id: E6U8E5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

663278:ETHHA RS12780
gene id: 663278:ETHHA_RS12780
uniprot id: E6U6G0
names: Similarity
messages: Belongs to the MotB family.

663278:ETHHA RS06165
gene id: 663278:ETHHA_RS06165
uniprot id: E6U5K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS08420
gene id: 663278:ETHHA_RS08420
uniprot id: E6U8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

663278:ETHHA RS04345
gene id: 663278:ETHHA_RS04345
uniprot id: E6U3C8
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

663278:ETHHA RS01860
gene id: 663278:ETHHA_RS01860
uniprot id: E6U814
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

663278:ETHHA RS13410
gene id: 663278:ETHHA_RS13410
uniprot id: E6U7N2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

663278:ETHHA RS14790
gene id: 663278:ETHHA_RS14790
uniprot id: E6U5S6
names: Similarity
messages: Belongs to the peptidase A24 family.

663278:ETHHA RS05645
gene id: 663278:ETHHA_RS05645
uniprot id: E6U4N6
names: Similarity
messages: Belongs to the UPF0473 family.

663278:ETHHA RS03465
gene id: 663278:ETHHA_RS03465
uniprot id: E6U9Y9
names: Similarity
messages: Belongs to the RutC family.

663278:ETHHA RS00120
gene id: 663278:ETHHA_RS00120
uniprot id: E6U5E6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS13185
gene id: 663278:ETHHA_RS13185
uniprot id: E6U738
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

663278:ETHHA RS08590
gene id: 663278:ETHHA_RS08590
uniprot id: E6U973
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS08150
gene id: 663278:ETHHA_RS08150
uniprot id: E6U8R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

663278:ETHHA RS02270
gene id: 663278:ETHHA_RS02270
uniprot id: E6U8N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

663278:ETHHA RS08795
gene id: 663278:ETHHA_RS08795
uniprot id: E6U9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS06545
gene id: 663278:ETHHA_RS06545
uniprot id: E6U668
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS08160
gene id: 663278:ETHHA_RS08160
uniprot id: E6U8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

663278:ETHHA RS07450
gene id: 663278:ETHHA_RS07450
uniprot id: E6U7J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

663278:ETHHA RS05215
gene id: 663278:ETHHA_RS05215
uniprot id: E6U478
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

663278:ETHHA RS10095
gene id: 663278:ETHHA_RS10095
uniprot id: E6U358
names: Similarity
messages: Belongs to the UPF0237 family.

663278:ETHHA RS05390
gene id: 663278:ETHHA_RS05390
uniprot id: E6U4B3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

663278:ETHHA RS10330
gene id: 663278:ETHHA_RS10330
uniprot id: E6U3A4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

663278:ETHHA RS07520
gene id: 663278:ETHHA_RS07520
uniprot id: E6U7K5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

663278:ETHHA RS12935
gene id: 663278:ETHHA_RS12935
uniprot id: E6U6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

663278:ETHHA RS12110
gene id: 663278:ETHHA_RS12110
uniprot id: E6U589
names: Similarity
messages: Belongs to the P(II) protein family.

663278:ETHHA RS13640
gene id: 663278:ETHHA_RS13640
uniprot id: E6U7S7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

663278:ETHHA RS12670
gene id: 663278:ETHHA_RS12670
uniprot id: E6U6D8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

663278:ETHHA RS00295
gene id: 663278:ETHHA_RS00295
uniprot id: E6U5I0
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS09300
gene id: 663278:ETHHA_RS09300
uniprot id: E6UA15
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS13945
gene id: 663278:ETHHA_RS13945
uniprot id: E6U8E0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

663278:ETHHA RS01625
gene id: 663278:ETHHA_RS01625
uniprot id: E6U7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

663278:ETHHA RS06540
gene id: 663278:ETHHA_RS06540
uniprot id: E6U667
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS11100
gene id: 663278:ETHHA_RS11100
uniprot id: E6U435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13395
gene id: 663278:ETHHA_RS13395
uniprot id: E6U7M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

663278:ETHHA RS10750
gene id: 663278:ETHHA_RS10750
uniprot id: E6U3X7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

663278:ETHHA RS13535
gene id: 663278:ETHHA_RS13535
uniprot id: E6U7Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

663278:ETHHA RS11285
gene id: 663278:ETHHA_RS11285
uniprot id: E6U4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS11110
gene id: 663278:ETHHA_RS11110
uniprot id: E6U437
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS01240
gene id: 663278:ETHHA_RS01240
uniprot id: E6U793
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS09925
gene id: 663278:ETHHA_RS09925
uniprot id: E6U2V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

663278:ETHHA RS14675
gene id: 663278:ETHHA_RS14675
uniprot id: E6U3J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

663278:ETHHA RS10005
gene id: 663278:ETHHA_RS10005
uniprot id: E6U340
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

663278:ETHHA RS02245
gene id: 663278:ETHHA_RS02245
uniprot id: E6U8M6
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS06690
gene id: 663278:ETHHA_RS06690
uniprot id: E6U697
names: Similarity
messages: Belongs to the TrpF family.

663278:ETHHA RS10290
gene id: 663278:ETHHA_RS10290
uniprot id: E6U396
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS13335
gene id: 663278:ETHHA_RS13335
uniprot id: E6U769
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

663278:ETHHA RS14090
gene id: 663278:ETHHA_RS14090
uniprot id: E6U8G2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS11290
gene id: 663278:ETHHA_RS11290
uniprot id: E6U4E5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS13110
gene id: 663278:ETHHA_RS13110
uniprot id: E6U723
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

663278:ETHHA RS07160
gene id: 663278:ETHHA_RS07160
uniprot id: E6U6Y8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

663278:ETHHA RS02275
gene id: 663278:ETHHA_RS02275
uniprot id: E6U8N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

663278:ETHHA RS08095
gene id: 663278:ETHHA_RS08095
uniprot id: E6U8Q5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

663278:ETHHA RS13955
gene id: 663278:ETHHA_RS13955
uniprot id: E6U8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

663278:ETHHA RS14135
gene id: 663278:ETHHA_RS14135
uniprot id: E6U8H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

663278:ETHHA RS12930
gene id: 663278:ETHHA_RS12930
uniprot id: E6U6J0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

663278:ETHHA RS02290
gene id: 663278:ETHHA_RS02290
uniprot id: E6U8N5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

663278:ETHHA RS01020
gene id: 663278:ETHHA_RS01020
uniprot id: E6U6Q1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

663278:ETHHA RS02310
gene id: 663278:ETHHA_RS02310
uniprot id: E6U8N9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

663278:ETHHA RS13490
gene id: 663278:ETHHA_RS13490
uniprot id: E6U7P7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

663278:ETHHA RS01890
gene id: 663278:ETHHA_RS01890
uniprot id: E6U820
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

663278:ETHHA RS08745
gene id: 663278:ETHHA_RS08745
uniprot id: E6U9A5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS09970
gene id: 663278:ETHHA_RS09970
uniprot id: E6U333
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS02485
gene id: 663278:ETHHA_RS02485
uniprot id: E6U622
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

663278:ETHHA RS10580
gene id: 663278:ETHHA_RS10580
uniprot id: E6U3M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

663278:ETHHA RS14575
gene id: 663278:ETHHA_RS14575
uniprot id: E6U7H9
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS10415
gene id: 663278:ETHHA_RS10415
uniprot id: E6U3J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

663278:ETHHA RS04775
gene id: 663278:ETHHA_RS04775
uniprot id: E6U3S7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13230
gene id: 663278:ETHHA_RS13230
uniprot id: E6U747
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

663278:ETHHA RS07155
gene id: 663278:ETHHA_RS07155
uniprot id: E6U6Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

663278:ETHHA RS01215
gene id: 663278:ETHHA_RS01215
uniprot id: E6U788
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

663278:ETHHA RS01945
gene id: 663278:ETHHA_RS01945
uniprot id: E6U831
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

663278:ETHHA RS00950
gene id: 663278:ETHHA_RS00950
uniprot id: E6U6N7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS01870
gene id: 663278:ETHHA_RS01870
uniprot id: E6U816
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS08690
gene id: 663278:ETHHA_RS08690
uniprot id: E6U994
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

663278:ETHHA RS10310
gene id: 663278:ETHHA_RS10310
uniprot id: E6U3A0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS01305
gene id: 663278:ETHHA_RS01305
uniprot id: E6U7A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

663278:ETHHA RS14735
gene id: 663278:ETHHA_RS14735
uniprot id: E6U4S4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS03695
gene id: 663278:ETHHA_RS03695
uniprot id: E6U2K5
names: Similarity
messages: Belongs to the UPF0229 family.

663278:ETHHA RS06495
gene id: 663278:ETHHA_RS06495
uniprot id: E6U5R8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

663278:ETHHA RS07655
gene id: 663278:ETHHA_RS07655
uniprot id: E6U837
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

663278:ETHHA RS06880
gene id: 663278:ETHHA_RS06880
uniprot id: E6U6D3
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS12775
gene id: 663278:ETHHA_RS12775
uniprot id: E6U6F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS00960
gene id: 663278:ETHHA_RS00960
uniprot id: E6U6N9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS01900
gene id: 663278:ETHHA_RS01900
uniprot id: E6U822
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

663278:ETHHA RS09495
gene id: 663278:ETHHA_RS09495
uniprot id: E6UA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

663278:ETHHA RS07555
gene id: 663278:ETHHA_RS07555
uniprot id: E6U7L2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

663278:ETHHA RS11070
gene id: 663278:ETHHA_RS11070
uniprot id: E6U429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

663278:ETHHA RS02940
gene id: 663278:ETHHA_RS02940
uniprot id: E6U9G0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

663278:ETHHA RS05305
gene id: 663278:ETHHA_RS05305
uniprot id: E6U497
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

663278:ETHHA RS05800
gene id: 663278:ETHHA_RS05800
uniprot id: E6U4Y7
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS00065
gene id: 663278:ETHHA_RS00065
uniprot id: E6U5D6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS08175
gene id: 663278:ETHHA_RS08175
uniprot id: E6U8S1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS13045
gene id: 663278:ETHHA_RS13045
uniprot id: E6U713
names: Similarity
messages: Belongs to the disproportionating enzyme family.

663278:ETHHA RS07750
gene id: 663278:ETHHA_RS07750
uniprot id: E6U855
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

663278:ETHHA RS11350
gene id: 663278:ETHHA_RS11350
uniprot id: E6U4F7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

663278:ETHHA RS13530
gene id: 663278:ETHHA_RS13530
uniprot id: E6U7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

663278:ETHHA RS12275
gene id: 663278:ETHHA_RS12275
uniprot id: E6U5C2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS12750
gene id: 663278:ETHHA_RS12750
uniprot id: E6U6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

663278:ETHHA RS10130
gene id: 663278:ETHHA_RS10130
uniprot id: E6U365
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

663278:ETHHA RS07005
gene id: 663278:ETHHA_RS07005
uniprot id: E6U6V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

663278:ETHHA RS02315
gene id: 663278:ETHHA_RS02315
uniprot id: E6U8P0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

663278:ETHHA RS12665
gene id: 663278:ETHHA_RS12665
uniprot id: E6U6D7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

663278:ETHHA RS02020
gene id: 663278:ETHHA_RS02020
uniprot id: E6U8I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

663278:ETHHA RS06800
gene id: 663278:ETHHA_RS06800
uniprot id: E6U6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

663278:ETHHA RS01680
gene id: 663278:ETHHA_RS01680
uniprot id: E6U7X9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

663278:ETHHA RS02010
gene id: 663278:ETHHA_RS02010
uniprot id: E6U8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

663278:ETHHA RS05290
gene id: 663278:ETHHA_RS05290
uniprot id: E6U494
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

663278:ETHHA RS09870
gene id: 663278:ETHHA_RS09870
uniprot id: E6U2U4
names: Similarity
messages: Belongs to the UPF0297 family.

663278:ETHHA RS00190
gene id: 663278:ETHHA_RS00190
uniprot id: E6U5G0
names: Similarity
messages: Belongs to the MecA family.

663278:ETHHA RS04205
gene id: 663278:ETHHA_RS04205
uniprot id: E6U326
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

663278:ETHHA RS02760
gene id: 663278:ETHHA_RS02760
uniprot id: E6U9C3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

663278:ETHHA RS01295
gene id: 663278:ETHHA_RS01295
uniprot id: E6U7A4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

663278:ETHHA RS03830
gene id: 663278:ETHHA_RS03830
uniprot id: E6U2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS00345
gene id: 663278:ETHHA_RS00345
uniprot id: E6U5J0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

663278:ETHHA RS06810
gene id: 663278:ETHHA_RS06810
uniprot id: E6U6C0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS13665
gene id: 663278:ETHHA_RS13665
uniprot id: E6U7T2
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

663278:ETHHA RS13455
gene id: 663278:ETHHA_RS13455
uniprot id: E6U7P1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

663278:ETHHA RS07235
gene id: 663278:ETHHA_RS07235
uniprot id: E6U704
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS01930
gene id: 663278:ETHHA_RS01930
uniprot id: E6U828
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

663278:ETHHA RS03280
gene id: 663278:ETHHA_RS03280
uniprot id: E6U9V2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

663278:ETHHA RS13350
gene id: 663278:ETHHA_RS13350
uniprot id: E6U772
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

663278:ETHHA RS14130
gene id: 663278:ETHHA_RS14130
uniprot id: E6U8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

663278:ETHHA RS01510
gene id: 663278:ETHHA_RS01510
uniprot id: E6U7E1
names: Similarity
messages: Belongs to the transpeptidase family.

663278:ETHHA RS14690
gene id: 663278:ETHHA_RS14690
uniprot id: E6U422
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS11410
gene id: 663278:ETHHA_RS11410
uniprot id: E6U4G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspH family.
messages: Spore core

663278:ETHHA RS05110
gene id: 663278:ETHHA_RS05110
uniprot id: E6U459
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

663278:ETHHA RS10905
gene id: 663278:ETHHA_RS10905
uniprot id: E6U3Z7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

663278:ETHHA RS00070
gene id: 663278:ETHHA_RS00070
uniprot id: E6U5D7
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

663278:ETHHA RS10500
gene id: 663278:ETHHA_RS10500
uniprot id: E6U3K9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

663278:ETHHA RS13355
gene id: 663278:ETHHA_RS13355
uniprot id: E6U773
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

663278:ETHHA RS11570
gene id: 663278:ETHHA_RS11570
uniprot id: E6U4S0
names: Similarity
messages: Belongs to the UPF0047 family.

663278:ETHHA RS03945
gene id: 663278:ETHHA_RS03945
uniprot id: E6U2X7
names: Similarity
messages: Belongs to the citrate synthase family.

663278:ETHHA RS00565
gene id: 663278:ETHHA_RS00565
uniprot id: E6U622
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

663278:ETHHA RS11190
gene id: 663278:ETHHA_RS11190
uniprot id: E6U4C5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

663278:ETHHA RS00115
gene id: 663278:ETHHA_RS00115
uniprot id: E6U5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

663278:ETHHA RS03955
gene id: 663278:ETHHA_RS03955
uniprot id: E6U2X9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

663278:ETHHA RS10615
gene id: 663278:ETHHA_RS10615
uniprot id: E6U3N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

663278:ETHHA RS09350
gene id: 663278:ETHHA_RS09350
uniprot id: E6UA26
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

663278:ETHHA RS07795
gene id: 663278:ETHHA_RS07795
uniprot id: E6U863
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS12765
gene id: 663278:ETHHA_RS12765
uniprot id: E6U6F7
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

663278:ETHHA RS05860
gene id: 663278:ETHHA_RS05860
uniprot id: E6U4Z9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

663278:ETHHA RS00860
gene id: 663278:ETHHA_RS00860
uniprot id: E6U6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

663278:ETHHA RS04560
gene id: 663278:ETHHA_RS04560
uniprot id: E6U3G3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

663278:ETHHA RS11320
gene id: 663278:ETHHA_RS11320
uniprot id: E6U4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS01995
gene id: 663278:ETHHA_RS01995
uniprot id: E6U8I2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

663278:ETHHA RS03905
gene id: 663278:ETHHA_RS03905
uniprot id: E6U2W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS00905
gene id: 663278:ETHHA_RS00905
uniprot id: E6U6M9
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS06040
gene id: 663278:ETHHA_RS06040
uniprot id: E6U535
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

663278:ETHHA RS05130
gene id: 663278:ETHHA_RS05130
uniprot id: E6U462
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

663278:ETHHA RS01175
gene id: 663278:ETHHA_RS01175
uniprot id: E6U6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

663278:ETHHA RS00900
gene id: 663278:ETHHA_RS00900
uniprot id: E6U6M8
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS13630
gene id: 663278:ETHHA_RS13630
uniprot id: E6U7S5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

663278:ETHHA RS09530
gene id: 663278:ETHHA_RS09530
uniprot id: E6UA60
names: Similarity
messages: Belongs to the peptidase C40 family.

663278:ETHHA RS09730
gene id: 663278:ETHHA_RS09730
uniprot id: E6U2R7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

663278:ETHHA RS02135
gene id: 663278:ETHHA_RS02135
uniprot id: E6U8L1
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS04385
gene id: 663278:ETHHA_RS04385
uniprot id: E6U3D4
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS10640
gene id: 663278:ETHHA_RS10640
uniprot id: E6U3N8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

663278:ETHHA RS00965
gene id: 663278:ETHHA_RS00965
uniprot id: E6U6P0
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS07535
gene id: 663278:ETHHA_RS07535
uniprot id: E6U7K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

663278:ETHHA RS11915
gene id: 663278:ETHHA_RS11915
uniprot id: E6U554
names: Similarity
messages: Belongs to the ABC transporter superfamily.

663278:ETHHA RS07640
gene id: 663278:ETHHA_RS07640
uniprot id: E6U834
names: Similarity
messages: Belongs to the UPF0145 family.

663278:ETHHA RS01920
gene id: 663278:ETHHA_RS01920
uniprot id: E6U826
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

663278:ETHHA RS00075
gene id: 663278:ETHHA_RS00075
uniprot id: E6U5D8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS13325
gene id: 663278:ETHHA_RS13325
uniprot id: E6U767
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

663278:ETHHA RS14540
gene id: 663278:ETHHA_RS14540
uniprot id: E6U687
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

663278:ETHHA RS11075
gene id: 663278:ETHHA_RS11075
uniprot id: E6U430
names: Similarity
messages: Belongs to the UDPGP type 2 family.

663278:ETHHA RS08340
gene id: 663278:ETHHA_RS08340
uniprot id: E6U8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

663278:ETHHA RS05920
gene id: 663278:ETHHA_RS05920
uniprot id: E6U512
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS02465
gene id: 663278:ETHHA_RS02465
uniprot id: E6U8Z5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

663278:ETHHA RS03725
gene id: 663278:ETHHA_RS03725
uniprot id: E6U2L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS05670
gene id: 663278:ETHHA_RS05670
uniprot id: E6U4N9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS03755
gene id: 663278:ETHHA_RS03755
uniprot id: E6U2L7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

663278:ETHHA RS08565
gene id: 663278:ETHHA_RS08565
uniprot id: E6U3T5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

663278:ETHHA RS05285
gene id: 663278:ETHHA_RS05285
uniprot id: E6U493
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

663278:ETHHA RS03550
gene id: 663278:ETHHA_RS03550
uniprot id: E6U2I1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

663278:ETHHA RS01415
gene id: 663278:ETHHA_RS01415
uniprot id: E6U7C6
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS04365
gene id: 663278:ETHHA_RS04365
uniprot id: E6U3D1
names: Similarity
messages: Belongs to the ArsC family.

663278:ETHHA RS13215
gene id: 663278:ETHHA_RS13215
uniprot id: E6U744
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

663278:ETHHA RS01865
gene id: 663278:ETHHA_RS01865
uniprot id: E6U815
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

663278:ETHHA RS04575
gene id: 663278:ETHHA_RS04575
uniprot id: E6U3G6
names: Similarity
messages: Belongs to the glycosyl hydrolase.

663278:ETHHA RS03270
gene id: 663278:ETHHA_RS03270
uniprot id: E6U9V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

663278:ETHHA RS00810
gene id: 663278:ETHHA_RS00810
uniprot id: E6U6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

663278:ETHHA RS08670
gene id: 663278:ETHHA_RS08670
uniprot id: E6U990
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

663278:ETHHA RS07025
gene id: 663278:ETHHA_RS07025
uniprot id: E6U6W1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

663278:ETHHA RS13775
gene id: 663278:ETHHA_RS13775
uniprot id: E6U7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

663278:ETHHA RS13480
gene id: 663278:ETHHA_RS13480
uniprot id: E6U7P5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

663278:ETHHA RS08260
gene id: 663278:ETHHA_RS08260
uniprot id: E6U8T8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

663278:ETHHA RS00045
gene id: 663278:ETHHA_RS00045
uniprot id: E6U5D1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

663278:ETHHA RS00030
gene id: 663278:ETHHA_RS00030
uniprot id: E6U5C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

663278:ETHHA RS03580
gene id: 663278:ETHHA_RS03580
uniprot id: E6U2I7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

663278:ETHHA RS07040
gene id: 663278:ETHHA_RS07040
uniprot id: E6U6W4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

663278:ETHHA RS04280
gene id: 663278:ETHHA_RS04280
uniprot id: E6U3B5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

663278:ETHHA RS07690
gene id: 663278:ETHHA_RS07690
uniprot id: E6U843
names: Similarity
messages: Belongs to the UPF0758 family.

663278:ETHHA RS12600
gene id: 663278:ETHHA_RS12600
uniprot id: E6U5Y3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

663278:ETHHA RS10545
gene id: 663278:ETHHA_RS10545
uniprot id: E6U3L8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS05420
gene id: 663278:ETHHA_RS05420
uniprot id: E6U4J1
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

663278:ETHHA RS04965
gene id: 663278:ETHHA_RS04965
uniprot id: E6U3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS06120
gene id: 663278:ETHHA_RS06120
uniprot id: E6U5J9
names: Similarity
messages: Belongs to the asp23 family.

663278:ETHHA RS13715
gene id: 663278:ETHHA_RS13715
uniprot id: E6U7U2
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

663278:ETHHA RS03790
gene id: 663278:ETHHA_RS03790
uniprot id: E6U2M4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

663278:ETHHA RS01965
gene id: 663278:ETHHA_RS01965
uniprot id: E6U8H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

663278:ETHHA RS10325
gene id: 663278:ETHHA_RS10325
uniprot id: E6U3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

663278:ETHHA RS13485
gene id: 663278:ETHHA_RS13485
uniprot id: E6U7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

663278:ETHHA RS01755
gene id: 663278:ETHHA_RS01755
uniprot id: E6U7Z4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS04350
gene id: 663278:ETHHA_RS04350
uniprot id: E6U3C9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

663278:ETHHA RS05190
gene id: 663278:ETHHA_RS05190
uniprot id: E6U473
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS01580
gene id: 663278:ETHHA_RS01580
uniprot id: E6U7V9
names: Similarity
messages: Belongs to the pyruvate kinase family.

663278:ETHHA RS14730
gene id: 663278:ETHHA_RS14730
uniprot id: E6U4R6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

663278:ETHHA RS04235
gene id: 663278:ETHHA_RS04235
uniprot id: E6U3A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS13040
gene id: 663278:ETHHA_RS13040
uniprot id: E6U712
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

663278:ETHHA RS03525
gene id: 663278:ETHHA_RS03525
uniprot id: E6U2H6
names: Similarity
messages: Belongs to the YggT family.

663278:ETHHA RS13460
gene id: 663278:ETHHA_RS13460
uniprot id: E6U7P2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

663278:ETHHA RS12675
gene id: 663278:ETHHA_RS12675
uniprot id: E6U6D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

663278:ETHHA RS06180
gene id: 663278:ETHHA_RS06180
uniprot id: E6U5L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS10115
gene id: 663278:ETHHA_RS10115
uniprot id: E6U362
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

663278:ETHHA RS10135
gene id: 663278:ETHHA_RS10135
uniprot id: E6U366
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

663278:ETHHA RS09700
gene id: 663278:ETHHA_RS09700
uniprot id: E6U2R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

663278:ETHHA RS13405
gene id: 663278:ETHHA_RS13405
uniprot id: E6U7N1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

663278:ETHHA RS03660
gene id: 663278:ETHHA_RS03660
uniprot id: E6U2J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

663278:ETHHA RS03775
gene id: 663278:ETHHA_RS03775
uniprot id: E6U2M1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

663278:ETHHA RS04030
gene id: 663278:ETHHA_RS04030
uniprot id: E6U2Z4
names: Similarity
messages: Belongs to the GSP E family.

663278:ETHHA RS08280
gene id: 663278:ETHHA_RS08280
uniprot id: E6U8U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

663278:ETHHA RS03740
gene id: 663278:ETHHA_RS03740
uniprot id: E6U2L4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

663278:ETHHA RS04190
gene id: 663278:ETHHA_RS04190
uniprot id: E6U323
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS03240
gene id: 663278:ETHHA_RS03240
uniprot id: E6U9U3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

663278:ETHHA RS11675
gene id: 663278:ETHHA_RS11675
uniprot id: E6U4U0
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

663278:ETHHA RS06285
gene id: 663278:ETHHA_RS06285
uniprot id: E6U5M9
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

663278:ETHHA RS11870
gene id: 663278:ETHHA_RS11870
uniprot id: E6U4X6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS10380
gene id: 663278:ETHHA_RS10380
uniprot id: E6U3I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

663278:ETHHA RS08595
gene id: 663278:ETHHA_RS08595
uniprot id: E6U974
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

663278:ETHHA RS01970
gene id: 663278:ETHHA_RS01970
uniprot id: E6U8H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

663278:ETHHA RS08205
gene id: 663278:ETHHA_RS08205
uniprot id: E6U8S7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

663278:ETHHA RS10145
gene id: 663278:ETHHA_RS10145
uniprot id: E6U368
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

663278:ETHHA RS01790
gene id: 663278:ETHHA_RS01790
uniprot id: E6U801
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

663278:ETHHA RS10740
gene id: 663278:ETHHA_RS10740
uniprot id: E6U3X5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS09705
gene id: 663278:ETHHA_RS09705
uniprot id: E6U2R2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

663278:ETHHA RS05585
gene id: 663278:ETHHA_RS05585
uniprot id: E6U4M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS10140
gene id: 663278:ETHHA_RS10140
uniprot id: E6U367
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

663278:ETHHA RS08165
gene id: 663278:ETHHA_RS08165
uniprot id: E6U8R9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

663278:ETHHA RS13620
gene id: 663278:ETHHA_RS13620
uniprot id: E6U7S3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

663278:ETHHA RS12755
gene id: 663278:ETHHA_RS12755
uniprot id: E6U6F5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

663278:ETHHA RS05465
gene id: 663278:ETHHA_RS05465
uniprot id: E6U4K1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

663278:ETHHA RS04605
gene id: 663278:ETHHA_RS04605
uniprot id: E6U3H2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

663278:ETHHA RS12690
gene id: 663278:ETHHA_RS12690
uniprot id: E6U6E2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

663278:ETHHA RS07315
gene id: 663278:ETHHA_RS07315
uniprot id: E6U7G4
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS05175
gene id: 663278:ETHHA_RS05175
uniprot id: E6U470
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

663278:ETHHA RS01620
gene id: 663278:ETHHA_RS01620
uniprot id: E6U7W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

663278:ETHHA RS08130
gene id: 663278:ETHHA_RS08130
uniprot id: E6U8R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

663278:ETHHA RS12925
gene id: 663278:ETHHA_RS12925
uniprot id: E6U6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

663278:ETHHA RS11455
gene id: 663278:ETHHA_RS11455
uniprot id: E6U4H6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS05525
gene id: 663278:ETHHA_RS05525
uniprot id: E6U4L2
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

663278:ETHHA RS05580
gene id: 663278:ETHHA_RS05580
uniprot id: E6U4M2
names: Similarity
messages: Belongs to the glutamine synthetase family.

663278:ETHHA RS13980
gene id: 663278:ETHHA_RS13980
uniprot id: E6U8E8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS01705
gene id: 663278:ETHHA_RS01705
uniprot id: E6U7Y4
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS07715
gene id: 663278:ETHHA_RS07715
uniprot id: E6U848
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

663278:ETHHA RS06965
gene id: 663278:ETHHA_RS06965
uniprot id: E6U6U9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

663278:ETHHA RS07320
gene id: 663278:ETHHA_RS07320
uniprot id: E6U7G5
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS01935
gene id: 663278:ETHHA_RS01935
uniprot id: E6U829
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

663278:ETHHA RS13705
gene id: 663278:ETHHA_RS13705
uniprot id: E6U7U0
names: Similarity
messages: Belongs to the peptidase M18 family.

663278:ETHHA RS10980
gene id: 663278:ETHHA_RS10980
uniprot id: E6U412
names: Similarity
messages: Belongs to the FemABX family.

663278:ETHHA RS11010
gene id: 663278:ETHHA_RS11010
uniprot id: E6U417
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS12330
gene id: 663278:ETHHA_RS12330
uniprot id: E6U5S9
names: Similarity
messages: Belongs to the GSP E family.

663278:ETHHA RS08225
gene id: 663278:ETHHA_RS08225
uniprot id: E6U8T1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

663278:ETHHA RS01825
gene id: 663278:ETHHA_RS01825
uniprot id: E6U808
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

663278:ETHHA RS04170
gene id: 663278:ETHHA_RS04170
uniprot id: E6U319
names: Subcellular Location Annotation
messages: Cytoplasm

663278:ETHHA RS01905
gene id: 663278:ETHHA_RS01905
uniprot id: E6U823
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

663278:ETHHA RS07875
gene id: 663278:ETHHA_RS07875
uniprot id: E6U879
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

663278:ETHHA RS14075
gene id: 663278:ETHHA_RS14075
uniprot id: E6U8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

663278:ETHHA RS11710
gene id: 663278:ETHHA_RS11710
uniprot id: E6U4U7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

663278:ETHHA RS03720
gene id: 663278:ETHHA_RS03720
uniprot id: E6U2L0
names: Similarity
messages: Belongs to the group II decarboxylase family.

663278:ETHHA RS13425
gene id: 663278:ETHHA_RS13425
uniprot id: E6U7N5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

663278:ETHHA RS09650
gene id: 663278:ETHHA_RS09650
uniprot id: E6U2Q4
names: Similarity
messages: Belongs to the EamA transporter family.

663278:ETHHA RS05595
gene id: 663278:ETHHA_RS05595
uniprot id: E6U4M5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

663278:ETHHA RS10350
gene id: 663278:ETHHA_RS10350
uniprot id: E6U3I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

663278:ETHHA RS07495
gene id: 663278:ETHHA_RS07495
uniprot id: E6U7K0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

663278:ETHHA RS02380
gene id: 663278:ETHHA_RS02380
uniprot id: E6U8Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

663278:ETHHA RS00705
gene id: 663278:ETHHA_RS00705
uniprot id: E6U646
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

663278:ETHHA RS02140
gene id: 663278:ETHHA_RS02140
uniprot id: E6U8L2
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS10450
gene id: 663278:ETHHA_RS10450
uniprot id: E6U3K0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS10425
gene id: 663278:ETHHA_RS10425
uniprot id: E6U3J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

663278:ETHHA RS11525
gene id: 663278:ETHHA_RS11525
uniprot id: E6U4R2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

663278:ETHHA RS04725
gene id: 663278:ETHHA_RS04725
uniprot id: E6U3R9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

663278:ETHHA RS00690
gene id: 663278:ETHHA_RS00690
uniprot id: E6U643
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

663278:ETHHA RS05280
gene id: 663278:ETHHA_RS05280
uniprot id: E6U492
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

663278:ETHHA RS10485
gene id: 663278:ETHHA_RS10485
uniprot id: E6U3K6
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS11130
gene id: 663278:ETHHA_RS11130
uniprot id: E6U4B4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

663278:ETHHA RS09860
gene id: 663278:ETHHA_RS09860
uniprot id: E6U2U2
names: Similarity
messages: Belongs to the FBPase class 3 family.

663278:ETHHA RS03370
gene id: 663278:ETHHA_RS03370
uniprot id: E6U9X0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

663278:ETHHA RS07300
gene id: 663278:ETHHA_RS07300
uniprot id: E6U7G1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS03965
gene id: 663278:ETHHA_RS03965
uniprot id: E6U2Y1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS11150
gene id: 663278:ETHHA_RS11150
uniprot id: E6U4B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

663278:ETHHA RS01345
gene id: 663278:ETHHA_RS01345
uniprot id: E6U7B2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

663278:ETHHA RS05370
gene id: 663278:ETHHA_RS05370
uniprot id: E6U4A9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

663278:ETHHA RS05915
gene id: 663278:ETHHA_RS05915
uniprot id: E6U511
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS02475
gene id: 663278:ETHHA_RS02475
uniprot id: E6U8Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

663278:ETHHA RS13510
gene id: 663278:ETHHA_RS13510
uniprot id: E6U7Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

663278:ETHHA RS00175
gene id: 663278:ETHHA_RS00175
uniprot id: E6U5F7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

663278:ETHHA RS00815
gene id: 663278:ETHHA_RS00815
uniprot id: E6U6L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

663278:ETHHA RS07740
gene id: 663278:ETHHA_RS07740
uniprot id: E6U853
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS07925
gene id: 663278:ETHHA_RS07925
uniprot id: E6U888
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

663278:ETHHA RS05200
gene id: 663278:ETHHA_RS05200
uniprot id: E6U475
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

663278:ETHHA RS02125
gene id: 663278:ETHHA_RS02125
uniprot id: E6U8K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

663278:ETHHA RS11880
gene id: 663278:ETHHA_RS11880
uniprot id: E6U4X8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS04690
gene id: 663278:ETHHA_RS04690
uniprot id: E6U3R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS12695
gene id: 663278:ETHHA_RS12695
uniprot id: E6U6E3
names: Similarity
messages: Belongs to the EamA transporter family.

663278:ETHHA RS07250
gene id: 663278:ETHHA_RS07250
uniprot id: E6U707
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

663278:ETHHA RS05300
gene id: 663278:ETHHA_RS05300
uniprot id: E6U496
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

663278:ETHHA RS01325
gene id: 663278:ETHHA_RS01325
uniprot id: E6U7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

663278:ETHHA RS03505
gene id: 663278:ETHHA_RS03505
uniprot id: E6U2H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

663278:ETHHA RS14230
gene id: 663278:ETHHA_RS14230
uniprot id: E6U7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

663278:ETHHA RS12895
gene id: 663278:ETHHA_RS12895
uniprot id: E6U6I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

663278:ETHHA RS01740
gene id: 663278:ETHHA_RS01740
uniprot id: E6U7Z1
names: Similarity
messages: Belongs to the RecJ family.

663278:ETHHA RS06170
gene id: 663278:ETHHA_RS06170
uniprot id: E6U5K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

663278:ETHHA RS07195
gene id: 663278:ETHHA_RS07195
uniprot id: E6U6Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

663278:ETHHA RS08355
gene id: 663278:ETHHA_RS08355
uniprot id: E6U8V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS06135
gene id: 663278:ETHHA_RS06135
uniprot id: E6U5K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

663278:ETHHA RS03890
gene id: 663278:ETHHA_RS03890
uniprot id: E6U2W6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

663278:ETHHA RS13310
gene id: 663278:ETHHA_RS13310
uniprot id: E6U763
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

663278:ETHHA RS01745
gene id: 663278:ETHHA_RS01745
uniprot id: E6U7Z2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

663278:ETHHA RS06680
gene id: 663278:ETHHA_RS06680
uniprot id: E6U695
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS02395
gene id: 663278:ETHHA_RS02395
uniprot id: E6U8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS09745
gene id: 663278:ETHHA_RS09745
uniprot id: E6U2S0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

663278:ETHHA RS03315
gene id: 663278:ETHHA_RS03315
uniprot id: E6U9V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

663278:ETHHA RS09810
gene id: 663278:ETHHA_RS09810
uniprot id: E6U2T2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS09670
gene id: 663278:ETHHA_RS09670
uniprot id: E6U2Q8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS08310
gene id: 663278:ETHHA_RS08310
uniprot id: E6U8U9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS05720
gene id: 663278:ETHHA_RS05720
uniprot id: E6U4P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13685
gene id: 663278:ETHHA_RS13685
uniprot id: E6U7T6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

663278:ETHHA RS06890
gene id: 663278:ETHHA_RS06890
uniprot id: E6U6T5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS11115
gene id: 663278:ETHHA_RS11115
uniprot id: E6U438
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS13890
gene id: 663278:ETHHA_RS13890
uniprot id: E6U8D0
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

663278:ETHHA RS11330
gene id: 663278:ETHHA_RS11330
uniprot id: E6U4F3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

663278:ETHHA RS07000
gene id: 663278:ETHHA_RS07000
uniprot id: E6U6V6
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

663278:ETHHA RS07600
gene id: 663278:ETHHA_RS07600
uniprot id: E6U7M1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS09875
gene id: 663278:ETHHA_RS09875
uniprot id: E6U2U5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

663278:ETHHA RS04730
gene id: 663278:ETHHA_RS04730
uniprot id: E6U3S0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

663278:ETHHA RS09305
gene id: 663278:ETHHA_RS09305
uniprot id: E6UA16
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

663278:ETHHA RS07525
gene id: 663278:ETHHA_RS07525
uniprot id: E6U7K6
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

663278:ETHHA RS02040
gene id: 663278:ETHHA_RS02040
uniprot id: E6U8J1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

663278:ETHHA RS05450
gene id: 663278:ETHHA_RS05450
uniprot id: E6U4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

663278:ETHHA RS03900
gene id: 663278:ETHHA_RS03900
uniprot id: E6U2W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

663278:ETHHA RS07635
gene id: 663278:ETHHA_RS07635
uniprot id: E6U833
names: Similarity
messages: Belongs to the transpeptidase family.

663278:ETHHA RS07140
gene id: 663278:ETHHA_RS07140
uniprot id: E6U6Y3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

663278:ETHHA RS07885
gene id: 663278:ETHHA_RS07885
uniprot id: E6U881
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

663278:ETHHA RS09080
gene id: 663278:ETHHA_RS09080
uniprot id: E6U9P5
names: Similarity
messages: Belongs to the HsdR family.

663278:ETHHA RS05615
gene id: 663278:ETHHA_RS05615
uniprot id: E6U4N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

663278:ETHHA RS08885
gene id: 663278:ETHHA_RS08885
uniprot id: E6U9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

663278:ETHHA RS06770
gene id: 663278:ETHHA_RS06770
uniprot id: E6U6B2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

663278:ETHHA RS03000
gene id: 663278:ETHHA_RS03000
uniprot id: E6U9H3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

663278:ETHHA RS04020
gene id: 663278:ETHHA_RS04020
uniprot id: E6U2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

663278:ETHHA RS01910
gene id: 663278:ETHHA_RS01910
uniprot id: E6U824
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

663278:ETHHA RS13795
gene id: 663278:ETHHA_RS13795
uniprot id: E6U8B1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

663278:ETHHA RS02875
gene id: 663278:ETHHA_RS02875
uniprot id: E6U9E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS08180
gene id: 663278:ETHHA_RS08180
uniprot id: E6U8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

663278:ETHHA RS00015
gene id: 663278:ETHHA_RS00015
uniprot id: E6U5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

663278:ETHHA RS00795
gene id: 663278:ETHHA_RS00795
uniprot id: E6U662
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS14045
gene id: 663278:ETHHA_RS14045
uniprot id: E6U8F3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

663278:ETHHA RS07255
gene id: 663278:ETHHA_RS07255
uniprot id: E6U708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

663278:ETHHA RS03880
gene id: 663278:ETHHA_RS03880
uniprot id: E6U2W4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

663278:ETHHA RS10280
gene id: 663278:ETHHA_RS10280
uniprot id: E6U394
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

663278:ETHHA RS10560
gene id: 663278:ETHHA_RS10560
uniprot id: E6U3M1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

663278:ETHHA RS08610
gene id: 663278:ETHHA_RS08610
uniprot id: E6U977
names: Similarity
messages: Belongs to the LacAB/RpiB family.

663278:ETHHA RS12760
gene id: 663278:ETHHA_RS12760
uniprot id: E6U6F6
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

663278:ETHHA RS05775
gene id: 663278:ETHHA_RS05775
uniprot id: E6U4Y2
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS00980
gene id: 663278:ETHHA_RS00980
uniprot id: E6U6P3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

663278:ETHHA RS01690
gene id: 663278:ETHHA_RS01690
uniprot id: E6U7Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

663278:ETHHA RS05950
gene id: 663278:ETHHA_RS05950
uniprot id: E6U518
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

663278:ETHHA RS04695
gene id: 663278:ETHHA_RS04695
uniprot id: E6U3R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

663278:ETHHA RS05935
gene id: 663278:ETHHA_RS05935
uniprot id: E6U515
names: Similarity
messages: Belongs to the CdaR family.

663278:ETHHA RS06155
gene id: 663278:ETHHA_RS06155
uniprot id: E6U5K6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

663278:ETHHA RS04900
gene id: 663278:ETHHA_RS04900
uniprot id: E6U3V1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

663278:ETHHA RS01695
gene id: 663278:ETHHA_RS01695
uniprot id: E6U7Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS00085
gene id: 663278:ETHHA_RS00085
uniprot id: E6U5E0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

663278:ETHHA RS00685
gene id: 663278:ETHHA_RS00685
uniprot id: E6U642
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

663278:ETHHA RS02880
gene id: 663278:ETHHA_RS02880
uniprot id: E6U9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS06205
gene id: 663278:ETHHA_RS06205
uniprot id: E6U5L3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS13575
gene id: 663278:ETHHA_RS13575
uniprot id: E6U7R4
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS11120
gene id: 663278:ETHHA_RS11120
uniprot id: E6U439
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS05780
gene id: 663278:ETHHA_RS05780
uniprot id: E6U4Y3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

663278:ETHHA RS13015
gene id: 663278:ETHHA_RS13015
uniprot id: E6U6K6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS01390
gene id: 663278:ETHHA_RS01390
uniprot id: E6U7C1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

663278:ETHHA RS01605
gene id: 663278:ETHHA_RS01605
uniprot id: E6U7W4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

663278:ETHHA RS00740
gene id: 663278:ETHHA_RS00740
uniprot id: E6U652
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

663278:ETHHA RS13130
gene id: 663278:ETHHA_RS13130
uniprot id: E6U727
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

663278:ETHHA RS08825
gene id: 663278:ETHHA_RS08825
uniprot id: E6U9J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

663278:ETHHA RS07485
gene id: 663278:ETHHA_RS07485
uniprot id: E6U7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

663278:ETHHA RS13435
gene id: 663278:ETHHA_RS13435
uniprot id: E6U7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

663278:ETHHA RS06975
gene id: 663278:ETHHA_RS06975
uniprot id: E6U6V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

663278:ETHHA RS03075
gene id: 663278:ETHHA_RS03075
uniprot id: E6U9I6
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS05850
gene id: 663278:ETHHA_RS05850
uniprot id: E6U4Z7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

663278:ETHHA RS05735
gene id: 663278:ETHHA_RS05735
uniprot id: E6U4Q2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS02375
gene id: 663278:ETHHA_RS02375
uniprot id: E6U8X9
names: Similarity
messages: Belongs to the DtxR/MntR family.

663278:ETHHA RS00735
gene id: 663278:ETHHA_RS00735
uniprot id: E6U651
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

663278:ETHHA RS07510
gene id: 663278:ETHHA_RS07510
uniprot id: E6U7K3
names: Similarity
messages: Belongs to the hemerythrin family.

663278:ETHHA RS01780
gene id: 663278:ETHHA_RS01780
uniprot id: E6U7Z9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

663278:ETHHA RS07290
gene id: 663278:ETHHA_RS07290
uniprot id: E6U7F9
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS11555
gene id: 663278:ETHHA_RS11555
uniprot id: E6U4R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

663278:ETHHA RS02805
gene id: 663278:ETHHA_RS02805
uniprot id: E6U9D3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS00195
gene id: 663278:ETHHA_RS00195
uniprot id: E6U5G1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

663278:ETHHA RS03745
gene id: 663278:ETHHA_RS03745
uniprot id: E6U2L5
names: Similarity
messages: Belongs to the class-I fumarase family.

663278:ETHHA RS13220
gene id: 663278:ETHHA_RS13220
uniprot id: E6U745
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

663278:ETHHA RS10945
gene id: 663278:ETHHA_RS10945
uniprot id: E6U405
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

663278:ETHHA RS08455
gene id: 663278:ETHHA_RS08455
uniprot id: E6U950
names: Similarity
messages: Belongs to the MT-A70-like family.

663278:ETHHA RS06955
gene id: 663278:ETHHA_RS06955
uniprot id: E6U6U7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

663278:ETHHA RS11495
gene id: 663278:ETHHA_RS11495
uniprot id: E6U4I4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

663278:ETHHA RS09955
gene id: 663278:ETHHA_RS09955
uniprot id: E6U2W0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

663278:ETHHA RS02080
gene id: 663278:ETHHA_RS02080
uniprot id: E6U8K0
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS11665
gene id: 663278:ETHHA_RS11665
uniprot id: E6U4T8
names: Similarity
messages: Belongs to the P(II) protein family.

663278:ETHHA RS14145
gene id: 663278:ETHHA_RS14145
uniprot id: E6U8H3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

663278:ETHHA RS05440
gene id: 663278:ETHHA_RS05440
uniprot id: E6U4J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

663278:ETHHA RS05710
gene id: 663278:ETHHA_RS05710
uniprot id: E6U4P7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS10785
gene id: 663278:ETHHA_RS10785
uniprot id: E6U3Y3
names: Similarity
messages: Belongs to the P(II) protein family.

663278:ETHHA RS09470
gene id: 663278:ETHHA_RS09470
uniprot id: E6UA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13730
gene id: 663278:ETHHA_RS13730
uniprot id: E6U7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

663278:ETHHA RS06725
gene id: 663278:ETHHA_RS06725
uniprot id: E6U6A4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS07105
gene id: 663278:ETHHA_RS07105
uniprot id: E6U6X6
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS09830
gene id: 663278:ETHHA_RS09830
uniprot id: E6U2T6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS01125
gene id: 663278:ETHHA_RS01125
uniprot id: E6U6S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

663278:ETHHA RS13940
gene id: 663278:ETHHA_RS13940
uniprot id: E6U8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

663278:ETHHA RS14385
gene id: 663278:ETHHA_RS14385
uniprot id: E6U2N4
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

663278:ETHHA RS12635
gene id: 663278:ETHHA_RS12635
uniprot id: E6U5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

663278:ETHHA RS05030
gene id: 663278:ETHHA_RS05030
uniprot id: E6U443
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

663278:ETHHA RS08770
gene id: 663278:ETHHA_RS08770
uniprot id: E6U9B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

663278:ETHHA RS01495
gene id: 663278:ETHHA_RS01495
uniprot id: E6U7D8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS02075
gene id: 663278:ETHHA_RS02075
uniprot id: E6U8J9
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS09390
gene id: 663278:ETHHA_RS09390
uniprot id: E6UA32
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS09655
gene id: 663278:ETHHA_RS09655
uniprot id: E6U2Q5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS10610
gene id: 663278:ETHHA_RS10610
uniprot id: E6U3N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

663278:ETHHA RS06985
gene id: 663278:ETHHA_RS06985
uniprot id: E6U6V3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

663278:ETHHA RS11105
gene id: 663278:ETHHA_RS11105
uniprot id: E6U436
names: Similarity
messages: Belongs to the P(II) protein family.

663278:ETHHA RS03435
gene id: 663278:ETHHA_RS03435
uniprot id: E6U9Y3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

663278:ETHHA RS01250
gene id: 663278:ETHHA_RS01250
uniprot id: E6U795
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

663278:ETHHA RS02035
gene id: 663278:ETHHA_RS02035
uniprot id: E6U8J0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

663278:ETHHA RS13770
gene id: 663278:ETHHA_RS13770
uniprot id: E6U7V2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

663278:ETHHA RS00550
gene id: 663278:ETHHA_RS00550
uniprot id: E6U619
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

663278:ETHHA RS07745
gene id: 663278:ETHHA_RS07745
uniprot id: E6U854
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

663278:ETHHA RS09385
gene id: 663278:ETHHA_RS09385
uniprot id: E6UA31
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

663278:ETHHA RS01085
gene id: 663278:ETHHA_RS01085
uniprot id: E6U6R4
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

663278:ETHHA RS07065
gene id: 663278:ETHHA_RS07065
uniprot id: E6U6W8
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS11955
gene id: 663278:ETHHA_RS11955
uniprot id: E6U559
names: Similarity
messages: Belongs to the manganese catalase family.

663278:ETHHA RS01985
gene id: 663278:ETHHA_RS01985
uniprot id: E6U8I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

663278:ETHHA RS13020
gene id: 663278:ETHHA_RS13020
uniprot id: E6U6K7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS12080
gene id: 663278:ETHHA_RS12080
uniprot id: E6U584
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS09900
gene id: 663278:ETHHA_RS09900
uniprot id: E6U2U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

663278:ETHHA RS05865
gene id: 663278:ETHHA_RS05865
uniprot id: E6U500
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

663278:ETHHA RS14125
gene id: 663278:ETHHA_RS14125
uniprot id: E6U8G9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

663278:ETHHA RS02175
gene id: 663278:ETHHA_RS02175
uniprot id: E6U8L9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

663278:ETHHA RS13235
gene id: 663278:ETHHA_RS13235
uniprot id: E6U748
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

663278:ETHHA RS13950
gene id: 663278:ETHHA_RS13950
uniprot id: E6U8E1
names: Similarity
messages: Belongs to the UPF0735 family.

663278:ETHHA RS08315
gene id: 663278:ETHHA_RS08315
uniprot id: E6U8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

663278:ETHHA RS05830
gene id: 663278:ETHHA_RS05830
uniprot id: E6U4Z3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

663278:ETHHA RS01990
gene id: 663278:ETHHA_RS01990
uniprot id: E6U8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

663278:ETHHA RS01640
gene id: 663278:ETHHA_RS01640
uniprot id: E6U7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

663278:ETHHA RS13260
gene id: 663278:ETHHA_RS13260
uniprot id: E6U753
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS08275
gene id: 663278:ETHHA_RS08275
uniprot id: E6U8U2
names: Similarity
messages: Belongs to the CinA family.

663278:ETHHA RS10595
gene id: 663278:ETHHA_RS10595
uniprot id: E6U3M9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

663278:ETHHA RS01235
gene id: 663278:ETHHA_RS01235
uniprot id: E6U792
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS05635
gene id: 663278:ETHHA_RS05635
uniprot id: E6U4N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

663278:ETHHA RS00755
gene id: 663278:ETHHA_RS00755
uniprot id: E6U655
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

663278:ETHHA RS01050
gene id: 663278:ETHHA_RS01050
uniprot id: E6U6Q8
names: Similarity
messages: Belongs to the asp23 family.

663278:ETHHA RS13275
gene id: 663278:ETHHA_RS13275
uniprot id: E6U756
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

663278:ETHHA RS13570
gene id: 663278:ETHHA_RS13570
uniprot id: E6U7R3
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS10420
gene id: 663278:ETHHA_RS10420
uniprot id: E6U3J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

663278:ETHHA RS03300
gene id: 663278:ETHHA_RS03300
uniprot id: E6U9V6
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

663278:ETHHA RS07700
gene id: 663278:ETHHA_RS07700
uniprot id: E6U845
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS02280
gene id: 663278:ETHHA_RS02280
uniprot id: E6U8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS05220
gene id: 663278:ETHHA_RS05220
uniprot id: E6U479
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

663278:ETHHA RS01500
gene id: 663278:ETHHA_RS01500
uniprot id: E6U7D9
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS00870
gene id: 663278:ETHHA_RS00870
uniprot id: E6U6M2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

663278:ETHHA RS08965
gene id: 663278:ETHHA_RS08965
uniprot id: E6U9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS03535
gene id: 663278:ETHHA_RS03535
uniprot id: E6U2H8
names: Subcellular Location Annotation
messages: Cytoplasm

663278:ETHHA RS00820
gene id: 663278:ETHHA_RS00820
uniprot id: E6U6L2
names: Similarity
messages: Belongs to the CdaR family.

663278:ETHHA RS02240
gene id: 663278:ETHHA_RS02240
uniprot id: E6U8M5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

663278:ETHHA RS09945
gene id: 663278:ETHHA_RS09945
uniprot id: E6U2V8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13000
gene id: 663278:ETHHA_RS13000
uniprot id: E6U6K4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

663278:ETHHA RS00765
gene id: 663278:ETHHA_RS00765
uniprot id: E6U657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

663278:ETHHA RS06145
gene id: 663278:ETHHA_RS06145
uniprot id: E6U5K4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

663278:ETHHA RS00895
gene id: 663278:ETHHA_RS00895
uniprot id: E6U6M7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

663278:ETHHA RS07355
gene id: 663278:ETHHA_RS07355
uniprot id: E6U7H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

663278:ETHHA RS13035
gene id: 663278:ETHHA_RS13035
uniprot id: E6U711
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

663278:ETHHA RS05195
gene id: 663278:ETHHA_RS05195
uniprot id: E6U474
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS11550
gene id: 663278:ETHHA_RS11550
uniprot id: E6U4R7
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS03230
gene id: 663278:ETHHA_RS03230
uniprot id: E6U9U1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

663278:ETHHA RS06685
gene id: 663278:ETHHA_RS06685
uniprot id: E6U696
names: Similarity
messages: Belongs to the TrpC family.

663278:ETHHA RS00090
gene id: 663278:ETHHA_RS00090
uniprot id: E6U5E1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS07705
gene id: 663278:ETHHA_RS07705
uniprot id: E6U846
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS09085
gene id: 663278:ETHHA_RS09085
uniprot id: E6U9P6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

663278:ETHHA RS07685
gene id: 663278:ETHHA_RS07685
uniprot id: E6U842
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

663278:ETHHA RS08615
gene id: 663278:ETHHA_RS08615
uniprot id: E6U978
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

663278:ETHHA RS03865
gene id: 663278:ETHHA_RS03865
uniprot id: E6U2W2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

663278:ETHHA RS12915
gene id: 663278:ETHHA_RS12915
uniprot id: E6U6I7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

663278:ETHHA RS04315
gene id: 663278:ETHHA_RS04315
uniprot id: E6U3C2
names: Similarity
messages: Belongs to the UPF0166 family.

663278:ETHHA RS10300
gene id: 663278:ETHHA_RS10300
uniprot id: E6U398
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS03490
gene id: 663278:ETHHA_RS03490
uniprot id: E6U2G9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

663278:ETHHA RS07880
gene id: 663278:ETHHA_RS07880
uniprot id: E6U880
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

663278:ETHHA RS15545
gene id: 663278:ETHHA_RS15545
uniprot id: E6U6Y2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

663278:ETHHA RS11065
gene id: 663278:ETHHA_RS11065
uniprot id: E6U428
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

663278:ETHHA RS04295
gene id: 663278:ETHHA_RS04295
uniprot id: E6U3B8
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

663278:ETHHA RS11645
gene id: 663278:ETHHA_RS11645
uniprot id: E6U4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

663278:ETHHA RS09055
gene id: 663278:ETHHA_RS09055
uniprot id: E6U9P0
names: Similarity
messages: Belongs to the HsdR family.

663278:ETHHA RS06175
gene id: 663278:ETHHA_RS06175
uniprot id: E6U5L0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

663278:ETHHA RS02015
gene id: 663278:ETHHA_RS02015
uniprot id: E6U8I6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

663278:ETHHA RS10160
gene id: 663278:ETHHA_RS10160
uniprot id: E6U371
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS10385
gene id: 663278:ETHHA_RS10385
uniprot id: E6U3I7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

663278:ETHHA RS05355
gene id: 663278:ETHHA_RS05355
uniprot id: E6U4A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

663278:ETHHA RS07505
gene id: 663278:ETHHA_RS07505
uniprot id: E6U7K2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

663278:ETHHA RS13320
gene id: 663278:ETHHA_RS13320
uniprot id: E6U766
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

663278:ETHHA RS08515
gene id: 663278:ETHHA_RS08515
uniprot id: E6U962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS02025
gene id: 663278:ETHHA_RS02025
uniprot id: E6U8I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

663278:ETHHA RS12630
gene id: 663278:ETHHA_RS12630
uniprot id: E6U5Y4
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

663278:ETHHA RS07020
gene id: 663278:ETHHA_RS07020
uniprot id: E6U6W0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

663278:ETHHA RS03110
gene id: 663278:ETHHA_RS03110
uniprot id: E6U9J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

663278:ETHHA RS10795
gene id: 663278:ETHHA_RS10795
uniprot id: E6U3Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS05365
gene id: 663278:ETHHA_RS05365
uniprot id: E6U4A8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

663278:ETHHA RS07420
gene id: 663278:ETHHA_RS07420
uniprot id: E6U7I6
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS01080
gene id: 663278:ETHHA_RS01080
uniprot id: E6U6R3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

663278:ETHHA RS06560
gene id: 663278:ETHHA_RS06560
uniprot id: E6U671
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

663278:ETHHA RS07580
gene id: 663278:ETHHA_RS07580
uniprot id: E6U7L7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

663278:ETHHA RS07395
gene id: 663278:ETHHA_RS07395
uniprot id: E6U7I0
names: Similarity
messages: Belongs to the NDK family.

663278:ETHHA RS11515
gene id: 663278:ETHHA_RS11515
uniprot id: E6U4R0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

663278:ETHHA RS12720
gene id: 663278:ETHHA_RS12720
uniprot id: E6U6E8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

663278:ETHHA RS05340
gene id: 663278:ETHHA_RS05340
uniprot id: E6U4A3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS11215
gene id: 663278:ETHHA_RS11215
uniprot id: E6U4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13345
gene id: 663278:ETHHA_RS13345
uniprot id: E6U771
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

663278:ETHHA RS09920
gene id: 663278:ETHHA_RS09920
uniprot id: E6U2V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

663278:ETHHA RS01720
gene id: 663278:ETHHA_RS01720
uniprot id: E6U7Y7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS09135
gene id: 663278:ETHHA_RS09135
uniprot id: E6U9Q6
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

663278:ETHHA RS11015
gene id: 663278:ETHHA_RS11015
uniprot id: E6U418
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS02265
gene id: 663278:ETHHA_RS02265
uniprot id: E6U8N0
names: Similarity
messages: Belongs to the UPF0102 family.

663278:ETHHA RS02155
gene id: 663278:ETHHA_RS02155
uniprot id: E6U8L5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

663278:ETHHA RS06665
gene id: 663278:ETHHA_RS06665
uniprot id: E6U692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

663278:ETHHA RS09915
gene id: 663278:ETHHA_RS09915
uniprot id: E6U2V2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

663278:ETHHA RS10360
gene id: 663278:ETHHA_RS10360
uniprot id: E6U3I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

663278:ETHHA RS13875
gene id: 663278:ETHHA_RS13875
uniprot id: E6U8C7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

663278:ETHHA RS06815
gene id: 663278:ETHHA_RS06815
uniprot id: E6U6C1
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

663278:ETHHA RS06590
gene id: 663278:ETHHA_RS06590
uniprot id: E6U677
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS07890
gene id: 663278:ETHHA_RS07890
uniprot id: E6U882
names: Similarity
messages: Belongs to the P(II) protein family.

663278:ETHHA RS00885
gene id: 663278:ETHHA_RS00885
uniprot id: E6U6M5
names: Similarity
messages: Belongs to the peptidase C1 family.

663278:ETHHA RS04000
gene id: 663278:ETHHA_RS04000
uniprot id: E6U2Y8
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

663278:ETHHA RS07545
gene id: 663278:ETHHA_RS07545
uniprot id: E6U7L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

663278:ETHHA RS03540
gene id: 663278:ETHHA_RS03540
uniprot id: E6U2H9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

663278:ETHHA RS06035
gene id: 663278:ETHHA_RS06035
uniprot id: E6U534
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

663278:ETHHA RS05090
gene id: 663278:ETHHA_RS05090
uniprot id: E6U455
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

663278:ETHHA RS12835
gene id: 663278:ETHHA_RS12835
uniprot id: E6U6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

663278:ETHHA RS13690
gene id: 663278:ETHHA_RS13690
uniprot id: E6U7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

663278:ETHHA RS10550
gene id: 663278:ETHHA_RS10550
uniprot id: E6U3L9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

663278:ETHHA RS02220
gene id: 663278:ETHHA_RS02220
uniprot id: E6U8M1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS13030
gene id: 663278:ETHHA_RS13030
uniprot id: E6U709
names: Similarity
messages: Belongs to the GerABKA family.

663278:ETHHA RS03395
gene id: 663278:ETHHA_RS03395
uniprot id: E6U9X5
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS07385
gene id: 663278:ETHHA_RS07385
uniprot id: E6U7H8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

663278:ETHHA RS10120
gene id: 663278:ETHHA_RS10120
uniprot id: E6U363
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS05445
gene id: 663278:ETHHA_RS05445
uniprot id: E6U4J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

663278:ETHHA RS13860
gene id: 663278:ETHHA_RS13860
uniprot id: E6U8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

663278:ETHHA RS11985
gene id: 663278:ETHHA_RS11985
uniprot id: E6U566
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

663278:ETHHA RS14110
gene id: 663278:ETHHA_RS14110
uniprot id: E6U8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

663278:ETHHA RS05065
gene id: 663278:ETHHA_RS05065
uniprot id: E6U450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

663278:ETHHA RS05180
gene id: 663278:ETHHA_RS05180
uniprot id: E6U471
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS08600
gene id: 663278:ETHHA_RS08600
uniprot id: E6U975
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

663278:ETHHA RS01655
gene id: 663278:ETHHA_RS01655
uniprot id: E6U7X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

663278:ETHHA RS10445
gene id: 663278:ETHHA_RS10445
uniprot id: E6U3J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

663278:ETHHA RS05590
gene id: 663278:ETHHA_RS05590
uniprot id: E6U4M4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

663278:ETHHA RS08195
gene id: 663278:ETHHA_RS08195
uniprot id: E6U8S5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

663278:ETHHA RS04085
gene id: 663278:ETHHA_RS04085
uniprot id: E6U305
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

663278:ETHHA RS07960
gene id: 663278:ETHHA_RS07960
uniprot id: E6U895
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

663278:ETHHA RS13360
gene id: 663278:ETHHA_RS13360
uniprot id: E6U774
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

663278:ETHHA RS13415
gene id: 663278:ETHHA_RS13415
uniprot id: E6U7N3
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS08245
gene id: 663278:ETHHA_RS08245
uniprot id: E6U8T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

663278:ETHHA RS09235
gene id: 663278:ETHHA_RS09235
uniprot id: E6UA00
names: Similarity
messages: Belongs to the peptidase S14 family.

663278:ETHHA RS10900
gene id: 663278:ETHHA_RS10900
uniprot id: E6U3Z6
names: Similarity
messages: Belongs to the DtxR/MntR family.

663278:ETHHA RS10765
gene id: 663278:ETHHA_RS10765
uniprot id: E6U3X9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS12745
gene id: 663278:ETHHA_RS12745
uniprot id: E6U6F3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS04815
gene id: 663278:ETHHA_RS04815
uniprot id: E6U3T5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

663278:ETHHA RS03710
gene id: 663278:ETHHA_RS03710
uniprot id: E6U2K8
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

663278:ETHHA RS08185
gene id: 663278:ETHHA_RS08185
uniprot id: E6U8S3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS04570
gene id: 663278:ETHHA_RS04570
uniprot id: E6U3G5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

663278:ETHHA RS08585
gene id: 663278:ETHHA_RS08585
uniprot id: E6U972
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

663278:ETHHA RS00715
gene id: 663278:ETHHA_RS00715
uniprot id: E6U648
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS07330
gene id: 663278:ETHHA_RS07330
uniprot id: E6U7G7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

663278:ETHHA RS04110
gene id: 663278:ETHHA_RS04110
uniprot id: E6U310
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS04610
gene id: 663278:ETHHA_RS04610
uniprot id: E6U3H3
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

663278:ETHHA RS07225
gene id: 663278:ETHHA_RS07225
uniprot id: E6U702
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

663278:ETHHA RS13390
gene id: 663278:ETHHA_RS13390
uniprot id: E6U781
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS07145
gene id: 663278:ETHHA_RS07145
uniprot id: E6U6Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

663278:ETHHA RS12185
gene id: 663278:ETHHA_RS12185
uniprot id: E6U5A4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

663278:ETHHA RS07440
gene id: 663278:ETHHA_RS07440
uniprot id: E6U7J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS03460
gene id: 663278:ETHHA_RS03460
uniprot id: E6U9Y8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

663278:ETHHA RS06305
gene id: 663278:ETHHA_RS06305
uniprot id: E6U5N3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

663278:ETHHA RS02770
gene id: 663278:ETHHA_RS02770
uniprot id: E6U9C6
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS03595
gene id: 663278:ETHHA_RS03595
uniprot id: E6U2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

663278:ETHHA RS14055
gene id: 663278:ETHHA_RS14055
uniprot id: E6U8F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

663278:ETHHA RS09910
gene id: 663278:ETHHA_RS09910
uniprot id: E6U2V1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

663278:ETHHA RS10180
gene id: 663278:ETHHA_RS10180
uniprot id: E6U374
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

663278:ETHHA RS12525
gene id: 663278:ETHHA_RS12525
uniprot id: E6U5W9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

663278:ETHHA RS09000
gene id: 663278:ETHHA_RS09000
uniprot id: E6U9N0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

663278:ETHHA RS12845
gene id: 663278:ETHHA_RS12845
uniprot id: E6U6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

663278:ETHHA RS02450
gene id: 663278:ETHHA_RS02450
uniprot id: E6U8Z2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

663278:ETHHA RS05295
gene id: 663278:ETHHA_RS05295
uniprot id: E6U495
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

663278:ETHHA RS00945
gene id: 663278:ETHHA_RS00945
uniprot id: E6U6N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

663278:ETHHA RS00800
gene id: 663278:ETHHA_RS00800
uniprot id: E6U6K9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

663278:ETHHA RS02030
gene id: 663278:ETHHA_RS02030
uniprot id: E6U8I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

663278:ETHHA RS02705
gene id: 663278:ETHHA_RS02705
uniprot id: E6U942
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

663278:ETHHA RS02995
gene id: 663278:ETHHA_RS02995
uniprot id: E6U9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS12730
gene id: 663278:ETHHA_RS12730
uniprot id: E6U6F0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS02320
gene id: 663278:ETHHA_RS02320
uniprot id: E6U8P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS12700
gene id: 663278:ETHHA_RS12700
uniprot id: E6U6E4
names: Similarity
messages: Belongs to the EamA transporter family.

663278:ETHHA RS11400
gene id: 663278:ETHHA_RS11400
uniprot id: E6U4G7
names: Similarity
messages: Belongs to the UPF0251 family.

663278:ETHHA RS13740
gene id: 663278:ETHHA_RS13740
uniprot id: E6U7U7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

663278:ETHHA RS12010
gene id: 663278:ETHHA_RS12010
uniprot id: E6U570
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

663278:ETHHA RS14400
gene id: 663278:ETHHA_RS14400
uniprot id: E6U314
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

663278:ETHHA RS05835
gene id: 663278:ETHHA_RS05835
uniprot id: E6U4Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS00040
gene id: 663278:ETHHA_RS00040
uniprot id: E6U5D0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

663278:ETHHA RS14105
gene id: 663278:ETHHA_RS14105
uniprot id: E6U8G5
names: Similarity
messages: Belongs to the ParB family.

663278:ETHHA RS04565
gene id: 663278:ETHHA_RS04565
uniprot id: E6U3G4
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Secreted

663278:ETHHA RS08170
gene id: 663278:ETHHA_RS08170
uniprot id: E6U8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

663278:ETHHA RS00750
gene id: 663278:ETHHA_RS00750
uniprot id: E6U654
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

663278:ETHHA RS10410
gene id: 663278:ETHHA_RS10410
uniprot id: E6U3J2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

663278:ETHHA RS00825
gene id: 663278:ETHHA_RS00825
uniprot id: E6U6L3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

663278:ETHHA RS10520
gene id: 663278:ETHHA_RS10520
uniprot id: E6U3L3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

663278:ETHHA RS01915
gene id: 663278:ETHHA_RS01915
uniprot id: E6U825
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

663278:ETHHA RS05885
gene id: 663278:ETHHA_RS05885
uniprot id: E6U505
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS09370
gene id: 663278:ETHHA_RS09370
uniprot id: E6UA29
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

663278:ETHHA RS01730
gene id: 663278:ETHHA_RS01730
uniprot id: E6U7Y9
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

663278:ETHHA RS00855
gene id: 663278:ETHHA_RS00855
uniprot id: E6U6L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

663278:ETHHA RS13295
gene id: 663278:ETHHA_RS13295
uniprot id: E6U760
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

663278:ETHHA RS07595
gene id: 663278:ETHHA_RS07595
uniprot id: E6U7M0
names: Similarity
messages: Belongs to the EamA transporter family.

663278:ETHHA RS13550
gene id: 663278:ETHHA_RS13550
uniprot id: E6U7Q9
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

663278:ETHHA RS10020
gene id: 663278:ETHHA_RS10020
uniprot id: E6U343
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

663278:ETHHA RS05230
gene id: 663278:ETHHA_RS05230
uniprot id: E6U481
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

663278:ETHHA RS01960
gene id: 663278:ETHHA_RS01960
uniprot id: E6U8H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

663278:ETHHA RS08620
gene id: 663278:ETHHA_RS08620
uniprot id: E6U979
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

663278:ETHHA RS04160
gene id: 663278:ETHHA_RS04160
uniprot id: E6U317
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS08125
gene id: 663278:ETHHA_RS08125
uniprot id: E6U8R1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

663278:ETHHA RS12535
gene id: 663278:ETHHA_RS12535
uniprot id: E6U5X1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

663278:ETHHA RS06695
gene id: 663278:ETHHA_RS06695
uniprot id: E6U698
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

663278:ETHHA RS06855
gene id: 663278:ETHHA_RS06855
uniprot id: E6U6C8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

663278:ETHHA RS12955
gene id: 663278:ETHHA_RS12955
uniprot id: E6U6J5
names: Similarity
messages: Belongs to the FlgD family.

663278:ETHHA RS10010
gene id: 663278:ETHHA_RS10010
uniprot id: E6U341
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

663278:ETHHA RS06825
gene id: 663278:ETHHA_RS06825
uniprot id: E6U6C3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS08980
gene id: 663278:ETHHA_RS08980
uniprot id: E6U9M6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

663278:ETHHA RS02370
gene id: 663278:ETHHA_RS02370
uniprot id: E6U8X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS13440
gene id: 663278:ETHHA_RS13440
uniprot id: E6U7N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

663278:ETHHA RS05315
gene id: 663278:ETHHA_RS05315
uniprot id: E6U499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

663278:ETHHA RS04165
gene id: 663278:ETHHA_RS04165
uniprot id: E6U318
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS09835
gene id: 663278:ETHHA_RS09835
uniprot id: E6U2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

663278:ETHHA RS04715
gene id: 663278:ETHHA_RS04715
uniprot id: E6U3R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS12115
gene id: 663278:ETHHA_RS12115
uniprot id: E6U590
names: Subcellular Location Annotation
messages: Periplasm

663278:ETHHA RS03305
gene id: 663278:ETHHA_RS03305
uniprot id: E6U9V7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

663278:ETHHA RS02500
gene id: 663278:ETHHA_RS02500
uniprot id: E6U902
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

663278:ETHHA RS05225
gene id: 663278:ETHHA_RS05225
uniprot id: E6U480
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

663278:ETHHA RS07190
gene id: 663278:ETHHA_RS07190
uniprot id: E6U6Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

663278:ETHHA RS08740
gene id: 663278:ETHHA_RS08740
uniprot id: E6U9A4
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

663278:ETHHA RS03495
gene id: 663278:ETHHA_RS03495
uniprot id: E6U2H0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

663278:ETHHA RS06980
gene id: 663278:ETHHA_RS06980
uniprot id: E6U6V2
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS08295
gene id: 663278:ETHHA_RS08295
uniprot id: E6U8U6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

663278:ETHHA RS05260
gene id: 663278:ETHHA_RS05260
uniprot id: E6U488
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS10570
gene id: 663278:ETHHA_RS10570
uniprot id: E6U3M3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

663278:ETHHA RS08505
gene id: 663278:ETHHA_RS08505
uniprot id: E6U960
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

663278:ETHHA RS14115
gene id: 663278:ETHHA_RS14115
uniprot id: E6U8G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

663278:ETHHA RS11660
gene id: 663278:ETHHA_RS11660
uniprot id: E6U4T7
names: Similarity
messages: Belongs to the P(II) protein family.

663278:ETHHA RS04615
gene id: 663278:ETHHA_RS04615
uniprot id: E6U3H4
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

663278:ETHHA RS07275
gene id: 663278:ETHHA_RS07275
uniprot id: E6U7F6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

663278:ETHHA RS12990
gene id: 663278:ETHHA_RS12990
uniprot id: E6U6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

663278:ETHHA RS08510
gene id: 663278:ETHHA_RS08510
uniprot id: E6U961
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS06270
gene id: 663278:ETHHA_RS06270
uniprot id: E6U3T5
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

663278:ETHHA RS13025
gene id: 663278:ETHHA_RS13025
uniprot id: E6U6K8
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

663278:ETHHA RS13655
gene id: 663278:ETHHA_RS13655
uniprot id: E6U7T0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

663278:ETHHA RS05695
gene id: 663278:ETHHA_RS05695
uniprot id: E6U4P4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

663278:ETHHA RS01845
gene id: 663278:ETHHA_RS01845
uniprot id: E6U811
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

663278:ETHHA RS07400
gene id: 663278:ETHHA_RS07400
uniprot id: E6U7I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

663278:ETHHA RS09430
gene id: 663278:ETHHA_RS09430
uniprot id: E6UA40
names: Similarity
messages: Belongs to the ParB family.

663278:ETHHA RS01665
gene id: 663278:ETHHA_RS01665
uniprot id: E6U7X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

663278:ETHHA RS07765
gene id: 663278:ETHHA_RS07765
uniprot id: E6U858
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

663278:ETHHA RS07930
gene id: 663278:ETHHA_RS07930
uniprot id: E6U889
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

663278:ETHHA RS01465
gene id: 663278:ETHHA_RS01465
uniprot id: E6U7D2
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS12500
gene id: 663278:ETHHA_RS12500
uniprot id: E6U5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

663278:ETHHA RS10670
gene id: 663278:ETHHA_RS10670
uniprot id: E6U3P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13150
gene id: 663278:ETHHA_RS13150
uniprot id: E6U731
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS01040
gene id: 663278:ETHHA_RS01040
uniprot id: E6U6Q6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

663278:ETHHA RS06300
gene id: 663278:ETHHA_RS06300
uniprot id: E6U5N2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

663278:ETHHA RS05045
gene id: 663278:ETHHA_RS05045
uniprot id: E6U446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

663278:ETHHA RS10630
gene id: 663278:ETHHA_RS10630
uniprot id: E6U3N6
names: Similarity
messages: Belongs to the RemA family.

663278:ETHHA RS09190
gene id: 663278:ETHHA_RS09190
uniprot id: E6U9R7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

663278:ETHHA RS13545
gene id: 663278:ETHHA_RS13545
uniprot id: E6U7Q8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

663278:ETHHA RS06845
gene id: 663278:ETHHA_RS06845
uniprot id: E6U6C7
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

663278:ETHHA RS09625
gene id: 663278:ETHHA_RS09625
uniprot id: E6U2P9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

663278:ETHHA RS01885
gene id: 663278:ETHHA_RS01885
uniprot id: E6U819
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

663278:ETHHA RS04645
gene id: 663278:ETHHA_RS04645
uniprot id: E6U3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS08985
gene id: 663278:ETHHA_RS08985
uniprot id: E6U9M7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

663278:ETHHA RS01560
gene id: 663278:ETHHA_RS01560
uniprot id: E6U7F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

663278:ETHHA RS10390
gene id: 663278:ETHHA_RS10390
uniprot id: E6U3I8
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

663278:ETHHA RS13780
gene id: 663278:ETHHA_RS13780
uniprot id: E6U7V4
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

663278:ETHHA RS07515
gene id: 663278:ETHHA_RS07515
uniprot id: E6U7K4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

663278:ETHHA RS03785
gene id: 663278:ETHHA_RS03785
uniprot id: E6U2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS13190
gene id: 663278:ETHHA_RS13190
uniprot id: E6U739
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

663278:ETHHA RS03420
gene id: 663278:ETHHA_RS03420
uniprot id: E6U9Y0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

663278:ETHHA RS00020
gene id: 663278:ETHHA_RS00020
uniprot id: E6U5C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

663278:ETHHA RS07175
gene id: 663278:ETHHA_RS07175
uniprot id: E6U6Z2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS07180
gene id: 663278:ETHHA_RS07180
uniprot id: E6U6Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

663278:ETHHA RS13375
gene id: 663278:ETHHA_RS13375
uniprot id: E6U777
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

663278:ETHHA RS10275
gene id: 663278:ETHHA_RS10275
uniprot id: E6U393
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS10395
gene id: 663278:ETHHA_RS10395
uniprot id: E6U3I9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

663278:ETHHA RS01115
gene id: 663278:ETHHA_RS01115
uniprot id: E6U6S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

663278:ETHHA RS12875
gene id: 663278:ETHHA_RS12875
uniprot id: E6U6H9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

663278:ETHHA RS07170
gene id: 663278:ETHHA_RS07170
uniprot id: E6U6Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

663278:ETHHA RS02470
gene id: 663278:ETHHA_RS02470
uniprot id: E6U8Z6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

663278:ETHHA RS00940
gene id: 663278:ETHHA_RS00940
uniprot id: E6U6N5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

663278:ETHHA RS03835
gene id: 663278:ETHHA_RS03835
uniprot id: E6U2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS12795
gene id: 663278:ETHHA_RS12795
uniprot id: E6U6G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

663278:ETHHA RS13400
gene id: 663278:ETHHA_RS13400
uniprot id: E6U7N0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

663278:ETHHA RS12945
gene id: 663278:ETHHA_RS12945
uniprot id: E6U6J3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

663278:ETHHA RS01265
gene id: 663278:ETHHA_RS01265
uniprot id: E6U798
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

663278:ETHHA RS11530
gene id: 663278:ETHHA_RS11530
uniprot id: E6U4R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

663278:ETHHA RS14095
gene id: 663278:ETHHA_RS14095
uniprot id: E6U8G3
names: Similarity
messages: Belongs to the ParB family.

663278:ETHHA RS14510
gene id: 663278:ETHHA_RS14510
uniprot id: E6U543
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

663278:ETHHA RS08955
gene id: 663278:ETHHA_RS08955
uniprot id: E6U9M1
names: Similarity
messages: Belongs to the glycosyl hydrolase.

663278:ETHHA RS13370
gene id: 663278:ETHHA_RS13370
uniprot id: E6U776
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS13595
gene id: 663278:ETHHA_RS13595
uniprot id: E6U7R8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

663278:ETHHA RS01630
gene id: 663278:ETHHA_RS01630
uniprot id: E6U7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

663278:ETHHA RS12800
gene id: 663278:ETHHA_RS12800
uniprot id: E6U6G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

663278:ETHHA RS08685
gene id: 663278:ETHHA_RS08685
uniprot id: E6U993
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

663278:ETHHA RS11755
gene id: 663278:ETHHA_RS11755
uniprot id: E6U4V6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS06670
gene id: 663278:ETHHA_RS06670
uniprot id: E6U693
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

663278:ETHHA RS08190
gene id: 663278:ETHHA_RS08190
uniprot id: E6U8S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

663278:ETHHA RS05760
gene id: 663278:ETHHA_RS05760
uniprot id: E6U4Q7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS05955
gene id: 663278:ETHHA_RS05955
uniprot id: E6U519
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

663278:ETHHA RS00760
gene id: 663278:ETHHA_RS00760
uniprot id: E6U656
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

663278:ETHHA RS10295
gene id: 663278:ETHHA_RS10295
uniprot id: E6U397
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS01660
gene id: 663278:ETHHA_RS01660
uniprot id: E6U7X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

663278:ETHHA RS07120
gene id: 663278:ETHHA_RS07120
uniprot id: E6U6X9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

663278:ETHHA RS06830
gene id: 663278:ETHHA_RS06830
uniprot id: E6U6C4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

663278:ETHHA RS03680
gene id: 663278:ETHHA_RS03680
uniprot id: E6U2K2
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS00995
gene id: 663278:ETHHA_RS00995
uniprot id: E6U6P6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS06345
gene id: 663278:ETHHA_RS06345
uniprot id: E6U5P0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

663278:ETHHA RS08230
gene id: 663278:ETHHA_RS08230
uniprot id: E6U8T2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

663278:ETHHA RS06475
gene id: 663278:ETHHA_RS06475
uniprot id: E6U5R4
names: Similarity
messages: Belongs to the ArsC family.

663278:ETHHA RS11085
gene id: 663278:ETHHA_RS11085
uniprot id: E6U432
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

663278:ETHHA RS08845
gene id: 663278:ETHHA_RS08845
uniprot id: E6U9J9
names: Similarity
messages: Belongs to the peptidase C40 family.

663278:ETHHA RS11395
gene id: 663278:ETHHA_RS11395
uniprot id: E6U4G6
names: Similarity
messages: Belongs to the NadC/ModD family.

663278:ETHHA RS00695
gene id: 663278:ETHHA_RS00695
uniprot id: E6U644
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

663278:ETHHA RS12900
gene id: 663278:ETHHA_RS12900
uniprot id: E6U6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

663278:ETHHA RS03295
gene id: 663278:ETHHA_RS03295
uniprot id: E6U9V5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

663278:ETHHA RS13115
gene id: 663278:ETHHA_RS13115
uniprot id: E6U724
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

663278:ETHHA RS03800
gene id: 663278:ETHHA_RS03800
uniprot id: E6U2M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

663278:ETHHA RS13140
gene id: 663278:ETHHA_RS13140
uniprot id: E6U729
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

663278:ETHHA RS12840
gene id: 663278:ETHHA_RS12840
uniprot id: E6U6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

663278:ETHHA RS06710
gene id: 663278:ETHHA_RS06710
uniprot id: E6U6A1
names: Similarity
messages: Belongs to the thioredoxin family.

663278:ETHHA RS03735
gene id: 663278:ETHHA_RS03735
uniprot id: E6U2L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

663278:ETHHA RS10225
gene id: 663278:ETHHA_RS10225
uniprot id: E6U383
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

663278:ETHHA RS12015
gene id: 663278:ETHHA_RS12015
uniprot id: E6U571
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS05870
gene id: 663278:ETHHA_RS05870
uniprot id: E6U501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

663278:ETHHA RS13900
gene id: 663278:ETHHA_RS13900
uniprot id: E6U8D2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

663278:ETHHA RS13245
gene id: 663278:ETHHA_RS13245
uniprot id: E6U750
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

663278:ETHHA RS02715
gene id: 663278:ETHHA_RS02715
uniprot id: E6U943
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

663278:ETHHA RS04290
gene id: 663278:ETHHA_RS04290
uniprot id: E6U3B7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

663278:ETHHA RS08110
gene id: 663278:ETHHA_RS08110
uniprot id: E6U8Q8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

663278:ETHHA RS11565
gene id: 663278:ETHHA_RS11565
uniprot id: E6U4R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

663278:ETHHA RS05715
gene id: 663278:ETHHA_RS05715
uniprot id: E6U4P8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS03225
gene id: 663278:ETHHA_RS03225
uniprot id: E6U9U0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

663278:ETHHA RS01280
gene id: 663278:ETHHA_RS01280
uniprot id: E6U7A1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS08255
gene id: 663278:ETHHA_RS08255
uniprot id: E6U8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

663278:ETHHA RS12860
gene id: 663278:ETHHA_RS12860
uniprot id: E6U6H6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

663278:ETHHA RS11680
gene id: 663278:ETHHA_RS11680
uniprot id: E6U4U1
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

663278:ETHHA RS10435
gene id: 663278:ETHHA_RS10435
uniprot id: E6U3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

663278:ETHHA RS05415
gene id: 663278:ETHHA_RS05415
uniprot id: E6U4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

663278:ETHHA RS01000
gene id: 663278:ETHHA_RS01000
uniprot id: E6U6P7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

663278:ETHHA RS02460
gene id: 663278:ETHHA_RS02460
uniprot id: E6U8Z4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

663278:ETHHA RS10605
gene id: 663278:ETHHA_RS10605
uniprot id: E6U3N1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

663278:ETHHA RS08305
gene id: 663278:ETHHA_RS08305
uniprot id: E6U8U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

663278:ETHHA RS14080
gene id: 663278:ETHHA_RS14080
uniprot id: E6U8G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

663278:ETHHA RS11425
gene id: 663278:ETHHA_RS11425
uniprot id: E6U4H2
names: Similarity
messages: Belongs to the TelA family.

663278:ETHHA RS03120
gene id: 663278:ETHHA_RS03120
uniprot id: E6U9R9
names: Similarity
messages: Belongs to the thioredoxin family.

663278:ETHHA RS04455
gene id: 663278:ETHHA_RS04455
uniprot id: E6U3E8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

663278:ETHHA RS13695
gene id: 663278:ETHHA_RS13695
uniprot id: E6U7T8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS10305
gene id: 663278:ETHHA_RS10305
uniprot id: E6U399
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

663278:ETHHA RS02305
gene id: 663278:ETHHA_RS02305
uniprot id: E6U8N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

663278:ETHHA RS01925
gene id: 663278:ETHHA_RS01925
uniprot id: E6U827
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

663278:ETHHA RS05765
gene id: 663278:ETHHA_RS05765
uniprot id: E6U4Y0
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS03105
gene id: 663278:ETHHA_RS03105
uniprot id: E6U9J1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

663278:ETHHA RS05380
gene id: 663278:ETHHA_RS05380
uniprot id: E6U4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

663278:ETHHA RS07205
gene id: 663278:ETHHA_RS07205
uniprot id: E6U6Z8
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS02000
gene id: 663278:ETHHA_RS02000
uniprot id: E6U8I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

663278:ETHHA RS03850
gene id: 663278:ETHHA_RS03850
uniprot id: E6U2N5
names: Similarity
messages: Belongs to the aldose epimerase family.

663278:ETHHA RS13315
gene id: 663278:ETHHA_RS13315
uniprot id: E6U764
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

663278:ETHHA RS02180
gene id: 663278:ETHHA_RS02180
uniprot id: E6U8M0
names: Similarity
messages: Belongs to the SleB family.

663278:ETHHA RS11020
gene id: 663278:ETHHA_RS11020
uniprot id: E6U419
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

663278:ETHHA RS04095
gene id: 663278:ETHHA_RS04095
uniprot id: E6U307
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

663278:ETHHA RS10375
gene id: 663278:ETHHA_RS10375
uniprot id: E6U3I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

663278:ETHHA RS07405
gene id: 663278:ETHHA_RS07405
uniprot id: E6U7I3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

663278:ETHHA RS07270
gene id: 663278:ETHHA_RS07270
uniprot id: E6U7F5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

663278:ETHHA RS02955
gene id: 663278:ETHHA_RS02955
uniprot id: E6U9G4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

663278:ETHHA RS13160
gene id: 663278:ETHHA_RS13160
uniprot id: E6U733
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

663278:ETHHA RS09995
gene id: 663278:ETHHA_RS09995
uniprot id: E6U338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

663278:ETHHA RS13540
gene id: 663278:ETHHA_RS13540
uniprot id: E6U7Q7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

663278:ETHHA RS01895
gene id: 663278:ETHHA_RS01895
uniprot id: E6U821
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

663278:ETHHA RS01950
gene id: 663278:ETHHA_RS01950
uniprot id: E6U832
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

663278:ETHHA RS07365
gene id: 663278:ETHHA_RS07365
uniprot id: E6U7H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

663278:ETHHA RS08155
gene id: 663278:ETHHA_RS08155
uniprot id: E6U8R7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

663278:ETHHA RS01140
gene id: 663278:ETHHA_RS01140
uniprot id: E6U6S6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

663278:ETHHA RS07785
gene id: 663278:ETHHA_RS07785
uniprot id: E6U862
names: Similarity
messages: Belongs to the EamA transporter family.

663278:ETHHA RS11910
gene id: 663278:ETHHA_RS11910
uniprot id: E6U553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS01260
gene id: 663278:ETHHA_RS01260
uniprot id: E6U797
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

663278:ETHHA RS03585
gene id: 663278:ETHHA_RS03585
uniprot id: E6U2I8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS08075
gene id: 663278:ETHHA_RS08075
uniprot id: E6U8Q1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

663278:ETHHA RS05650
gene id: 663278:ETHHA_RS05650
uniprot id: E6U4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS11785
gene id: 663278:ETHHA_RS11785
uniprot id: E6U4W2
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS11655
gene id: 663278:ETHHA_RS11655
uniprot id: E6U4T6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

663278:ETHHA RS01955
gene id: 663278:ETHHA_RS01955
uniprot id: E6U8H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

663278:ETHHA RS13760
gene id: 663278:ETHHA_RS13760
uniprot id: E6U7V0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

663278:ETHHA RS01600
gene id: 663278:ETHHA_RS01600
uniprot id: E6U7W3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

663278:ETHHA RS01410
gene id: 663278:ETHHA_RS01410
uniprot id: E6U7C5
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS00990
gene id: 663278:ETHHA_RS00990
uniprot id: E6U6P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

663278:ETHHA RS11140
gene id: 663278:ETHHA_RS11140
uniprot id: E6U4B6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

663278:ETHHA RS05655
gene id: 663278:ETHHA_RS05655
uniprot id: E6U4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS10100
gene id: 663278:ETHHA_RS10100
uniprot id: E6U359
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

663278:ETHHA RS05360
gene id: 663278:ETHHA_RS05360
uniprot id: E6U4A7
names: Similarity
messages: Belongs to the IMPACT family.

663278:ETHHA RS12880
gene id: 663278:ETHHA_RS12880
uniprot id: E6U6I0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

663278:ETHHA RS06125
gene id: 663278:ETHHA_RS06125
uniprot id: E6U5K0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

663278:ETHHA RS13420
gene id: 663278:ETHHA_RS13420
uniprot id: E6U7N4
names: Similarity
messages: Belongs to the CpsD/CapB family.

663278:ETHHA RS00135
gene id: 663278:ETHHA_RS00135
uniprot id: E6U5E9
names: Similarity
messages: Belongs to the UPF0111 family.

663278:ETHHA RS03380
gene id: 663278:ETHHA_RS03380
uniprot id: E6U9X2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

663278:ETHHA RS10000
gene id: 663278:ETHHA_RS10000
uniprot id: E6U339
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

663278:ETHHA RS01940
gene id: 663278:ETHHA_RS01940
uniprot id: E6U830
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

663278:ETHHA RS00150
gene id: 663278:ETHHA_RS00150
uniprot id: E6U5F2
names: Similarity
messages: Belongs to the ThiD family.

663278:ETHHA RS03875
gene id: 663278:ETHHA_RS03875
uniprot id: E6U2W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

663278:ETHHA RS00130
gene id: 663278:ETHHA_RS00130
uniprot id: E6U5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

663278:ETHHA RS12550
gene id: 663278:ETHHA_RS12550
uniprot id: E6U5X4
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS08970
gene id: 663278:ETHHA_RS08970
uniprot id: E6U9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS00790
gene id: 663278:ETHHA_RS00790
uniprot id: E6U661
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

663278:ETHHA RS03860
gene id: 663278:ETHHA_RS03860
uniprot id: E6U2N7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

663278:ETHHA RS01525
gene id: 663278:ETHHA_RS01525
uniprot id: E6U7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

663278:ETHHA RS10125
gene id: 663278:ETHHA_RS10125
uniprot id: E6U364
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

663278:ETHHA RS08910
gene id: 663278:ETHHA_RS08910
uniprot id: E6U9L2
names: Similarity
messages: Belongs to the ParB family.

663278:ETHHA RS09895
gene id: 663278:ETHHA_RS09895
uniprot id: E6U2U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

663278:ETHHA RS08830
gene id: 663278:ETHHA_RS08830
uniprot id: E6U9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

663278:ETHHA RS10040
gene id: 663278:ETHHA_RS10040
uniprot id: E6U347
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

663278:ETHHA RS04975
gene id: 663278:ETHHA_RS04975
uniprot id: E6U3W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

663278:ETHHA RS08235
gene id: 663278:ETHHA_RS08235
uniprot id: E6U8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

663278:ETHHA RS03840
gene id: 663278:ETHHA_RS03840
uniprot id: E6U2N3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

663278:ETHHA RS06700
gene id: 663278:ETHHA_RS06700
uniprot id: E6U699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

663278:ETHHA RS10680
gene id: 663278:ETHHA_RS10680
uniprot id: E6U3P6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

663278:ETHHA RS14470
gene id: 663278:ETHHA_RS14470
uniprot id: E6U4L6
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS06160
gene id: 663278:ETHHA_RS06160
uniprot id: E6U5K7
names: Similarity
messages: Belongs to the TlyA family.

663278:ETHHA RS04080
gene id: 663278:ETHHA_RS04080
uniprot id: E6U304
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS00710
gene id: 663278:ETHHA_RS00710
uniprot id: E6U647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

663278:ETHHA RS03915
gene id: 663278:ETHHA_RS03915
uniprot id: E6U2X1
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

663278:ETHHA RS10555
gene id: 663278:ETHHA_RS10555
uniprot id: E6U3M0
names: Similarity
messages: Belongs to the DHPS family.

663278:ETHHA RS11520
gene id: 663278:ETHHA_RS11520
uniprot id: E6U4R1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

663278:ETHHA RS02980
gene id: 663278:ETHHA_RS02980
uniprot id: E6U9G9
names: Similarity
messages: Belongs to the P(II) protein family.

663278:ETHHA RS13815
gene id: 663278:ETHHA_RS13815
uniprot id: E6U8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

663278:ETHHA RS06705
gene id: 663278:ETHHA_RS06705
uniprot id: E6U6A0
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS13565
gene id: 663278:ETHHA_RS13565
uniprot id: E6U7R2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

663278:ETHHA RS01480
gene id: 663278:ETHHA_RS01480
uniprot id: E6U7D5
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS05425
gene id: 663278:ETHHA_RS05425
uniprot id: E6U4J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

663278:ETHHA RS10635
gene id: 663278:ETHHA_RS10635
uniprot id: E6U3N7
names: Similarity
messages: Belongs to the YicC/YloC family.

663278:ETHHA RS00205
gene id: 663278:ETHHA_RS00205
uniprot id: E6U5G3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

663278:ETHHA RS01320
gene id: 663278:ETHHA_RS01320
uniprot id: E6U7A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

663278:ETHHA RS07900
gene id: 663278:ETHHA_RS07900
uniprot id: E6U884
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-98 inactivates the nitrogenase reductase and regulates nitrogenase activity.

663278:ETHHA RS09545
gene id: 663278:ETHHA_RS09545
uniprot id: E6UA64
names: Similarity
messages: Belongs to the type IA topoisomerase family.

663278:ETHHA RS11780
gene id: 663278:ETHHA_RS11780
uniprot id: E6U4W1
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS03515
gene id: 663278:ETHHA_RS03515
uniprot id: E6U2H4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

663278:ETHHA RS05275
gene id: 663278:ETHHA_RS05275
uniprot id: E6U491
names: Subcellular Location Annotation
messages: Membrane

663278:ETHHA RS12000
gene id: 663278:ETHHA_RS12000
uniprot id: E6U568
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

663278:ETHHA RS00095
gene id: 663278:ETHHA_RS00095
uniprot id: E6U5E2
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

663278:ETHHA RS08090
gene id: 663278:ETHHA_RS08090
uniprot id: E6U8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

663278:ETHHA RS05430
gene id: 663278:ETHHA_RS05430
uniprot id: E6U4J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

663278:ETHHA RS11505
gene id: 663278:ETHHA_RS11505
uniprot id: E6U4Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.