662755:CRES RS04100
gene id: 662755:CRES_RS04100
uniprot id: F8E014
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

662755:CRES RS06575
gene id: 662755:CRES_RS06575
uniprot id: F8DYC2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

662755:CRES RS09530
gene id: 662755:CRES_RS09530
uniprot id: F8E1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

662755:CRES RS10955
gene id: 662755:CRES_RS10955
uniprot id: F8E3E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

662755:CRES RS11290
gene id: 662755:CRES_RS11290
uniprot id: F8E3K8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

662755:CRES RS01880
gene id: 662755:CRES_RS01880
uniprot id: F8DXI0
names: Similarity
messages: Belongs to the FPG family.

662755:CRES RS05830
gene id: 662755:CRES_RS05830
uniprot id: F8E331
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

662755:CRES RS05370
gene id: 662755:CRES_RS05370
uniprot id: F8E2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

662755:CRES RS07490
gene id: 662755:CRES_RS07490
uniprot id: F8DZI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

662755:CRES RS06765
gene id: 662755:CRES_RS06765
uniprot id: F8DYK4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

662755:CRES RS04315
gene id: 662755:CRES_RS04315
uniprot id: F8E0F5
names: Similarity
messages: Belongs to the TrpC family.

662755:CRES RS03720
gene id: 662755:CRES_RS03720
uniprot id: F8DZN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

662755:CRES RS08475
gene id: 662755:CRES_RS08475
uniprot id: F8E0K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

662755:CRES RS05340
gene id: 662755:CRES_RS05340
uniprot id: F8E277
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

662755:CRES RS02440
gene id: 662755:CRES_RS02440
uniprot id: F8DYE2
names: Similarity
messages: Belongs to the UPF0145 family.

662755:CRES RS08395
gene id: 662755:CRES_RS08395
uniprot id: F8E0I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

662755:CRES RS08790
gene id: 662755:CRES_RS08790
uniprot id: F8E0X3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

662755:CRES RS01270
gene id: 662755:CRES_RS01270
uniprot id: F8E2F9
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

662755:CRES RS03905
gene id: 662755:CRES_RS03905
uniprot id: F8DZR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

662755:CRES RS03235
gene id: 662755:CRES_RS03235
uniprot id: F8DZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

662755:CRES RS05800
gene id: 662755:CRES_RS05800
uniprot id: F8E325
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

662755:CRES RS04210
gene id: 662755:CRES_RS04210
uniprot id: F8E0D4
names: Similarity
messages: Belongs to the HSP15 family.

662755:CRES RS02500
gene id: 662755:CRES_RS02500
uniprot id: F8DYF4
names: Similarity
messages: Belongs to the glutamate synthase family.

662755:CRES RS04845
gene id: 662755:CRES_RS04845
uniprot id: F8E0T1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

662755:CRES RS01070
gene id: 662755:CRES_RS01070
uniprot id: F8E211
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

662755:CRES RS01405
gene id: 662755:CRES_RS01405
uniprot id: F8E2I4
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

662755:CRES RS00895
gene id: 662755:CRES_RS00895
uniprot id: F8E1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

662755:CRES RS07295
gene id: 662755:CRES_RS07295
uniprot id: F8DZ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

662755:CRES RS02455
gene id: 662755:CRES_RS02455
uniprot id: F8DYE5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

662755:CRES RS07525
gene id: 662755:CRES_RS07525
uniprot id: F8DZJ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

662755:CRES RS02905
gene id: 662755:CRES_RS02905
uniprot id: F8DYT3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

662755:CRES RS09860
gene id: 662755:CRES_RS09860
uniprot id: F8E2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

662755:CRES RS03320
gene id: 662755:CRES_RS03320
uniprot id: F8DZA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

662755:CRES RS03495
gene id: 662755:CRES_RS03495
uniprot id: F8DZE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

662755:CRES RS00980
gene id: 662755:CRES_RS00980
uniprot id: F8E1Z3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

662755:CRES RS04120
gene id: 662755:CRES_RS04120
uniprot id: F8E018
names: Similarity
messages: Belongs to the YggT family.

662755:CRES RS04045
gene id: 662755:CRES_RS04045
uniprot id: F8E003
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

662755:CRES RS09725
gene id: 662755:CRES_RS09725
uniprot id: F8E2C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

662755:CRES RS09660
gene id: 662755:CRES_RS09660
uniprot id: F8E2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

662755:CRES RS08570
gene id: 662755:CRES_RS08570
uniprot id: F8E0M2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

662755:CRES RS05520
gene id: 662755:CRES_RS05520
uniprot id: F8E2L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

662755:CRES RS02985
gene id: 662755:CRES_RS02985
uniprot id: F8DZ00
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05355
gene id: 662755:CRES_RS05355
uniprot id: F8E280
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

662755:CRES RS06740
gene id: 662755:CRES_RS06740
uniprot id: F8DYK0
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS11275
gene id: 662755:CRES_RS11275
uniprot id: F8E3K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

662755:CRES RS10840
gene id: 662755:CRES_RS10840
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS07060
gene id: 662755:CRES_RS07060
uniprot id: F8DYX7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

662755:CRES RS08285
gene id: 662755:CRES_RS08285
uniprot id: F8E085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

662755:CRES RS07310
gene id: 662755:CRES_RS07310
uniprot id: F8DZ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

662755:CRES RS11035
gene id: 662755:CRES_RS11035
uniprot id: F8E3G0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

662755:CRES RS00500
gene id: 662755:CRES_RS00500
uniprot id: F8E107
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS09815
gene id: 662755:CRES_RS09815
uniprot id: F8E2N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

662755:CRES RS02430
gene id: 662755:CRES_RS02430
uniprot id: F8DYE0
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS01755
gene id: 662755:CRES_RS01755
uniprot id: F8DXF5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

662755:CRES RS05645
gene id: 662755:CRES_RS05645
uniprot id: F8E2Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS00025
gene id: 662755:CRES_RS00025
uniprot id: F8E092
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

662755:CRES RS04135
gene id: 662755:CRES_RS04135
uniprot id: F8E021
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

662755:CRES RS09065
gene id: 662755:CRES_RS09065
uniprot id: F8E1F5
names: Similarity
messages: Belongs to the citrate synthase family.

662755:CRES RS06760
gene id: 662755:CRES_RS06760
uniprot id: F8DYK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

662755:CRES RS03945
gene id: 662755:CRES_RS03945
uniprot id: F8DZY3
names: Similarity
messages: Belongs to the peptidase C40 family.

662755:CRES RS05680
gene id: 662755:CRES_RS05680
uniprot id: F8E301
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

662755:CRES RS06235
gene id: 662755:CRES_RS06235
uniprot id: F8DY06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

662755:CRES RS11115
gene id: 662755:CRES_RS11115
uniprot id: F8E3H4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS01695
gene id: 662755:CRES_RS01695
uniprot id: F8E0R0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS08640
gene id: 662755:CRES_RS08640
uniprot id: F8E0U6
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS03925
gene id: 662755:CRES_RS03925
uniprot id: F8DZS0
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

662755:CRES RS06770
gene id: 662755:CRES_RS06770
uniprot id: F8DYK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

662755:CRES RS06035
gene id: 662755:CRES_RS06035
uniprot id: F8DXL6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

662755:CRES RS00110
gene id: 662755:CRES_RS00110
uniprot id: F8E0A6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS10545
gene id: 662755:CRES_RS10545
uniprot id: F8DXQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

662755:CRES RS01115
gene id: 662755:CRES_RS01115
uniprot id: F8E220
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

662755:CRES RS09820
gene id: 662755:CRES_RS09820
uniprot id: F8E2N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

662755:CRES RS04810
gene id: 662755:CRES_RS04810
uniprot id: F8E0S4
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05750
gene id: 662755:CRES_RS05750
uniprot id: F8E315
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

662755:CRES RS09695
gene id: 662755:CRES_RS09695
uniprot id: F8E2B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

662755:CRES RS00220
gene id: 662755:CRES_RS00220
uniprot id: F8E0N1
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05600
gene id: 662755:CRES_RS05600
uniprot id: F8E2Y5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

662755:CRES RS06360
gene id: 662755:CRES_RS06360
uniprot id: F8DY31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

662755:CRES RS06225
gene id: 662755:CRES_RS06225
uniprot id: F8DY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662755:CRES RS09455
gene id: 662755:CRES_RS09455
uniprot id: F8E1X2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

662755:CRES RS06405
gene id: 662755:CRES_RS06405
uniprot id: F8DY87
names: Similarity
messages: Belongs to the MQO family.

662755:CRES RS07230
gene id: 662755:CRES_RS07230
uniprot id: F8DZ71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

662755:CRES RS09450
gene id: 662755:CRES_RS09450
uniprot id: F8E1X1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

662755:CRES RS05505
gene id: 662755:CRES_RS05505
uniprot id: F8E2L3
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS09685
gene id: 662755:CRES_RS09685
uniprot id: F8E2B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

662755:CRES RS05665
gene id: 662755:CRES_RS05665
uniprot id: F8E2Z8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

662755:CRES RS02495
gene id: 662755:CRES_RS02495
uniprot id: F8DYF3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

662755:CRES RS08610
gene id: 662755:CRES_RS08610
uniprot id: F8E0U0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

662755:CRES RS01980
gene id: 662755:CRES_RS01980
uniprot id: F8DXV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

662755:CRES RS09385
gene id: 662755:CRES_RS09385
uniprot id: F8E1V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

662755:CRES RS06620
gene id: 662755:CRES_RS06620
uniprot id: F8DYD1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

662755:CRES RS06265
gene id: 662755:CRES_RS06265
uniprot id: F8DY12
names: Similarity
messages: Belongs to the PspA/IM30 family.

662755:CRES RS03535
gene id: 662755:CRES_RS03535
uniprot id: F8DZF0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

662755:CRES RS09560
gene id: 662755:CRES_RS09560
uniprot id: F8E287
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

662755:CRES RS03435
gene id: 662755:CRES_RS03435
uniprot id: F8DZD0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

662755:CRES RS02925
gene id: 662755:CRES_RS02925
uniprot id: F8DYT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PorA family.
messages: Forms water-filled channels that favor the permeation of cations.
messages: cell wall

662755:CRES RS00115
gene id: 662755:CRES_RS00115
uniprot id: F8E0A8
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS09550
gene id: 662755:CRES_RS09550
uniprot id: F8E285
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS03555
gene id: 662755:CRES_RS03555
uniprot id: F8DZF4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

662755:CRES RS10745
gene id: 662755:CRES_RS10745
uniprot id: F8E3A8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

662755:CRES RS08440
gene id: 662755:CRES_RS08440
uniprot id: F8E0J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS08910
gene id: 662755:CRES_RS08910
uniprot id: F8E0Z7
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

662755:CRES RS06330
gene id: 662755:CRES_RS06330
uniprot id: F8DY25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

662755:CRES RS01570
gene id: 662755:CRES_RS01570
uniprot id: F8E2W5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662755:CRES RS09105
gene id: 662755:CRES_RS09105
uniprot id: F8E1G4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662755:CRES RS08430
gene id: 662755:CRES_RS08430
uniprot id: F8E0J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

662755:CRES RS06180
gene id: 662755:CRES_RS06180
uniprot id: F8DXZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

662755:CRES RS00730
gene id: 662755:CRES_RS00730
uniprot id: F8E1J1
names: Similarity
messages: Belongs to the FPG family.

662755:CRES RS09850
gene id: 662755:CRES_RS09850
uniprot id: F8E2N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

662755:CRES RS06175
gene id: 662755:CRES_RS06175
uniprot id: F8DXZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

662755:CRES RS06120
gene id: 662755:CRES_RS06120
uniprot id: F8DXY3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS01730
gene id: 662755:CRES_RS01730
uniprot id: F8DXF0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

662755:CRES RS08360
gene id: 662755:CRES_RS08360
uniprot id: F8E0I0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

662755:CRES RS06465
gene id: 662755:CRES_RS06465
uniprot id: F8DY99
names: Similarity
messages: Belongs to the ABC transporter superfamily.

662755:CRES RS04285
gene id: 662755:CRES_RS04285
uniprot id: F8E0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

662755:CRES RS04165
gene id: 662755:CRES_RS04165
uniprot id: F8E0C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

662755:CRES RS08930
gene id: 662755:CRES_RS08930
uniprot id: F8E1C8
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

662755:CRES RS08825
gene id: 662755:CRES_RS08825
uniprot id: F8E0Y0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

662755:CRES RS09235
gene id: 662755:CRES_RS09235
uniprot id: F8E1S9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS03080
gene id: 662755:CRES_RS03080
uniprot id: F8DZ18
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

662755:CRES RS05570
gene id: 662755:CRES_RS05570
uniprot id: F8E2M6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

662755:CRES RS04525
gene id: 662755:CRES_RS04525
uniprot id: F8E173
names: Similarity
messages: Belongs to the peptidase S14 family.

662755:CRES RS06725
gene id: 662755:CRES_RS06725
uniprot id: F8DYJ7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

662755:CRES RS10800
gene id: 662755:CRES_RS10800
uniprot id: F8E3B7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

662755:CRES RS07350
gene id: 662755:CRES_RS07350
uniprot id: F8DZ95
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

662755:CRES RS07425
gene id: 662755:CRES_RS07425
uniprot id: F8DZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

662755:CRES RS00370
gene id: 662755:CRES_RS00370
uniprot id: F8E0R0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS03640
gene id: 662755:CRES_RS03640
uniprot id: F8DZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

662755:CRES RS03115
gene id: 662755:CRES_RS03115
uniprot id: F8DZ24
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS00610
gene id: 662755:CRES_RS00610
uniprot id: F8E123
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

662755:CRES RS06650
gene id: 662755:CRES_RS06650
uniprot id: F8DYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

662755:CRES RS01065
gene id: 662755:CRES_RS01065
uniprot id: F8E210
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662755:CRES RS01135
gene id: 662755:CRES_RS01135
uniprot id: F8E224
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS04960
gene id: 662755:CRES_RS04960
uniprot id: F8E1Q1
names: Similarity
messages: Belongs to the TlyA family.

662755:CRES RS06340
gene id: 662755:CRES_RS06340
uniprot id: F8DY27
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

662755:CRES RS00890
gene id: 662755:CRES_RS00890
uniprot id: F8E1M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

662755:CRES RS09305
gene id: 662755:CRES_RS09305
uniprot id: F8E1U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

662755:CRES RS08015
gene id: 662755:CRES_RS08015
uniprot id: F8E034
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

662755:CRES RS05130
gene id: 662755:CRES_RS05130
uniprot id: F8E234
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS07110
gene id: 662755:CRES_RS07110
uniprot id: F8DYY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

662755:CRES RS03315
gene id: 662755:CRES_RS03315
uniprot id: F8DZA6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

662755:CRES RS01860
gene id: 662755:CRES_RS01860
uniprot id: F8DXH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS00535
gene id: 662755:CRES_RS00535
uniprot id: F8E0R0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS08265
gene id: 662755:CRES_RS08265
uniprot id: F8E081
names: Similarity
messages: Belongs to the CsoR family.

662755:CRES RS07670
gene id: 662755:CRES_RS07670
uniprot id: F8DZS9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

662755:CRES RS02350
gene id: 662755:CRES_RS02350
uniprot id: F8DY76
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

662755:CRES RS06315
gene id: 662755:CRES_RS06315
uniprot id: F8DY22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

662755:CRES RS00735
gene id: 662755:CRES_RS00735
uniprot id: F8E1J2
names: Similarity
messages: Belongs to the GARS family.

662755:CRES RS02650
gene id: 662755:CRES_RS02650
uniprot id: F8DYN2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

662755:CRES RS09565
gene id: 662755:CRES_RS09565
uniprot id: F8E288
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

662755:CRES RS05125
gene id: 662755:CRES_RS05125
uniprot id: F8E233
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS02705
gene id: 662755:CRES_RS02705
uniprot id: F8DYP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

662755:CRES RS10070
gene id: 662755:CRES_RS10070
uniprot id: F8E2S8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

662755:CRES RS01010
gene id: 662755:CRES_RS01010
uniprot id: F8E1Z9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

662755:CRES RS10260
gene id: 662755:CRES_RS10260
uniprot id: F8E366
names: Similarity
messages: Belongs to the peptidase M1 family.

662755:CRES RS03610
gene id: 662755:CRES_RS03610
uniprot id: F8DZG5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

662755:CRES RS06355
gene id: 662755:CRES_RS06355
uniprot id: F8DY30
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS08195
gene id: 662755:CRES_RS08195
uniprot id: F8E068
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

662755:CRES RS08215
gene id: 662755:CRES_RS08215
uniprot id: F8E072
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

662755:CRES RS02210
gene id: 662755:CRES_RS02210
uniprot id: F8DY50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

662755:CRES RS08840
gene id: 662755:CRES_RS08840
uniprot id: F8E0Y3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

662755:CRES RS03560
gene id: 662755:CRES_RS03560
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS05585
gene id: 662755:CRES_RS05585
uniprot id: F8E2M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

662755:CRES RS05055
gene id: 662755:CRES_RS05055
uniprot id: F8E1S0
names: Similarity
messages: Belongs to the peptidase S33 family.

662755:CRES RS03220
gene id: 662755:CRES_RS03220
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS06230
gene id: 662755:CRES_RS06230
uniprot id: F8DY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662755:CRES RS05670
gene id: 662755:CRES_RS05670
uniprot id: F8E2Z9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS01650
gene id: 662755:CRES_RS01650
uniprot id: F8E2Y1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

662755:CRES RS06415
gene id: 662755:CRES_RS06415
uniprot id: F8DY89
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

662755:CRES RS04295
gene id: 662755:CRES_RS04295
uniprot id: F8E0F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

662755:CRES RS03980
gene id: 662755:CRES_RS03980
uniprot id: F8DZZ0
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

662755:CRES RS07865
gene id: 662755:CRES_RS07865
uniprot id: F8DZW5
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS07260
gene id: 662755:CRES_RS07260
uniprot id: F8DZ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

662755:CRES RS00560
gene id: 662755:CRES_RS00560
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS00520
gene id: 662755:CRES_RS00520
uniprot id: F8E111
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

662755:CRES RS01410
gene id: 662755:CRES_RS01410
uniprot id: F8E2I5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

662755:CRES RS04070
gene id: 662755:CRES_RS04070
uniprot id: F8E008
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

662755:CRES RS09675
gene id: 662755:CRES_RS09675
uniprot id: F8E2B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

662755:CRES RS07660
gene id: 662755:CRES_RS07660
uniprot id: F8DZS7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS05620
gene id: 662755:CRES_RS05620
uniprot id: F8E2Y9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

662755:CRES RS00960
gene id: 662755:CRES_RS00960
uniprot id: F8E1Y9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

662755:CRES RS04965
gene id: 662755:CRES_RS04965
uniprot id: F8E1Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS04320
gene id: 662755:CRES_RS04320
uniprot id: F8E0F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

662755:CRES RS07740
gene id: 662755:CRES_RS07740
uniprot id: F8DZU1
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS03775
gene id: 662755:CRES_RS03775
uniprot id: F8DZP1
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

662755:CRES RS00580
gene id: 662755:CRES_RS00580
uniprot id: F8E117
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

662755:CRES RS11670
gene id: 662755:CRES_RS11670
uniprot id: F8E2Q4
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS03485
gene id: 662755:CRES_RS03485
uniprot id: F8DZE0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

662755:CRES RS01955
gene id: 662755:CRES_RS01955
uniprot id: F8DXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

662755:CRES RS08620
gene id: 662755:CRES_RS08620
uniprot id: F8E0U2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

662755:CRES RS03620
gene id: 662755:CRES_RS03620
uniprot id: F8DZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

662755:CRES RS07210
gene id: 662755:CRES_RS07210
uniprot id: F8DZ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS02285
gene id: 662755:CRES_RS02285
uniprot id: F8DY63
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

662755:CRES RS08505
gene id: 662755:CRES_RS08505
uniprot id: F8E0K9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

662755:CRES RS09610
gene id: 662755:CRES_RS09610
uniprot id: F8E298
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

662755:CRES RS08465
gene id: 662755:CRES_RS08465
uniprot id: F8E0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

662755:CRES RS09355
gene id: 662755:CRES_RS09355
uniprot id: F8E1V3
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

662755:CRES RS06145
gene id: 662755:CRES_RS06145
uniprot id: F8DXY8
names: Similarity
messages: Belongs to the neutral ceramidase family.

662755:CRES RS03015
gene id: 662755:CRES_RS03015
uniprot id: F8DZ06
names: Similarity
messages: Belongs to the ABC transporter superfamily.

662755:CRES RS04820
gene id: 662755:CRES_RS04820
uniprot id: F8E0S6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

662755:CRES RS09405
gene id: 662755:CRES_RS09405
uniprot id: F8E1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

662755:CRES RS11250
gene id: 662755:CRES_RS11250
uniprot id: F8E3K1
names: Similarity
messages: Belongs to the thioredoxin family.

662755:CRES RS00900
gene id: 662755:CRES_RS00900
uniprot id: F8E1M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

662755:CRES RS08535
gene id: 662755:CRES_RS08535
uniprot id: F8E0L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

662755:CRES RS04970
gene id: 662755:CRES_RS04970
uniprot id: F8E1Q3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

662755:CRES RS01540
gene id: 662755:CRES_RS01540
uniprot id: F8E2V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

662755:CRES RS07290
gene id: 662755:CRES_RS07290
uniprot id: F8DZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

662755:CRES RS04330
gene id: 662755:CRES_RS04330
uniprot id: F8E0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

662755:CRES RS04015
gene id: 662755:CRES_RS04015
uniprot id: F8DZZ7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

662755:CRES RS00605
gene id: 662755:CRES_RS00605
uniprot id: F8E122
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

662755:CRES RS11235
gene id: 662755:CRES_RS11235
uniprot id: F8E3J8
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS08745
gene id: 662755:CRES_RS08745
uniprot id: F8E0R0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS00195
gene id: 662755:CRES_RS00195
uniprot id: F8E0M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

662755:CRES RS00010
gene id: 662755:CRES_RS00010
uniprot id: F8E089
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

662755:CRES RS08405
gene id: 662755:CRES_RS08405
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS05685
gene id: 662755:CRES_RS05685
uniprot id: F8E302
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

662755:CRES RS01455
gene id: 662755:CRES_RS01455
uniprot id: F8E2U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

662755:CRES RS09205
gene id: 662755:CRES_RS09205
uniprot id: F8E1I5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

662755:CRES RS06110
gene id: 662755:CRES_RS06110
uniprot id: F8DXY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS01130
gene id: 662755:CRES_RS01130
uniprot id: F8E223
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

662755:CRES RS01625
gene id: 662755:CRES_RS01625
uniprot id: F8E2X6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

662755:CRES RS09830
gene id: 662755:CRES_RS09830
uniprot id: F8E2N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

662755:CRES RS04425
gene id: 662755:CRES_RS04425
uniprot id: F8E153
names: Similarity
messages: Belongs to the peptidase C15 family.

662755:CRES RS01035
gene id: 662755:CRES_RS01035
uniprot id: F8E204
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

662755:CRES RS09835
gene id: 662755:CRES_RS09835
uniprot id: F8E2N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

662755:CRES RS07100
gene id: 662755:CRES_RS07100
uniprot id: F8DYY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS03150
gene id: 662755:CRES_RS03150
uniprot id: F8DZ30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

662755:CRES RS06805
gene id: 662755:CRES_RS06805
uniprot id: F8DYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

662755:CRES RS04800
gene id: 662755:CRES_RS04800
uniprot id: F8E1C5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

662755:CRES RS09535
gene id: 662755:CRES_RS09535
uniprot id: F8E282
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

662755:CRES RS00965
gene id: 662755:CRES_RS00965
uniprot id: F8E1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

662755:CRES RS08455
gene id: 662755:CRES_RS08455
uniprot id: F8E0J9
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS02125
gene id: 662755:CRES_RS02125
uniprot id: F8DXX8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

662755:CRES RS05990
gene id: 662755:CRES_RS05990
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS02535
gene id: 662755:CRES_RS02535
uniprot id: F8DYG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

662755:CRES RS10580
gene id: 662755:CRES_RS10580
uniprot id: F8DXR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS04010
gene id: 662755:CRES_RS04010
uniprot id: F8DZZ6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

662755:CRES RS09570
gene id: 662755:CRES_RS09570
uniprot id: F8E289
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

662755:CRES RS00250
gene id: 662755:CRES_RS00250
uniprot id: F8E0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS08335
gene id: 662755:CRES_RS08335
uniprot id: F8E0H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

662755:CRES RS04735
gene id: 662755:CRES_RS04735
uniprot id: F8E1B1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

662755:CRES RS04900
gene id: 662755:CRES_RS04900
uniprot id: F8E1P2
names: Similarity
messages: Belongs to the UPF0434 family.

662755:CRES RS06630
gene id: 662755:CRES_RS06630
uniprot id: F8DYH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

662755:CRES RS09765
gene id: 662755:CRES_RS09765
uniprot id: F8E2C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

662755:CRES RS02000
gene id: 662755:CRES_RS02000
uniprot id: F8DXV3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

662755:CRES RS01935
gene id: 662755:CRES_RS01935
uniprot id: F8DXU0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662755:CRES RS10235
gene id: 662755:CRES_RS10235
uniprot id: F8E360
names: Cofactor
messages: Can also use Mn(2+) ion.

662755:CRES RS09700
gene id: 662755:CRES_RS09700
uniprot id: F8E2B5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

662755:CRES RS04995
gene id: 662755:CRES_RS04995
uniprot id: F8E1Q8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS05035
gene id: 662755:CRES_RS05035
uniprot id: F8E1R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

662755:CRES RS01760
gene id: 662755:CRES_RS01760
uniprot id: F8DXF6
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS08300
gene id: 662755:CRES_RS08300
uniprot id: F8E0G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

662755:CRES RS09215
gene id: 662755:CRES_RS09215
uniprot id: F8E1I6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

662755:CRES RS09390
gene id: 662755:CRES_RS09390
uniprot id: F8E1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

662755:CRES RS08630
gene id: 662755:CRES_RS08630
uniprot id: F8E0U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

662755:CRES RS01545
gene id: 662755:CRES_RS01545
uniprot id: F8E2W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

662755:CRES RS01420
gene id: 662755:CRES_RS01420
uniprot id: F8E2T5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

662755:CRES RS06590
gene id: 662755:CRES_RS06590
uniprot id: F8DYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

662755:CRES RS05855
gene id: 662755:CRES_RS05855
uniprot id: F8DXI7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

662755:CRES RS06680
gene id: 662755:CRES_RS06680
uniprot id: F8DYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

662755:CRES RS01920
gene id: 662755:CRES_RS01920
uniprot id: F8DXT7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

662755:CRES RS06515
gene id: 662755:CRES_RS06515
uniprot id: F8DYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

662755:CRES RS01170
gene id: 662755:CRES_RS01170
uniprot id: F8E2D9
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

662755:CRES RS03205
gene id: 662755:CRES_RS03205
uniprot id: F8DZ39
names: Similarity
messages: Belongs to the LacAB/RpiB family.

662755:CRES RS03920
gene id: 662755:CRES_RS03920
uniprot id: F8DZR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

662755:CRES RS08675
gene id: 662755:CRES_RS08675
uniprot id: F8E0V3
names: Similarity
messages: Belongs to the AccD/PCCB family.

662755:CRES RS08550
gene id: 662755:CRES_RS08550
uniprot id: F8E0L8
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS12655
gene id: 662755:CRES_RS12655
uniprot id: F8DXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

662755:CRES RS11400
gene id: 662755:CRES_RS11400
uniprot id: F8DXW5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

662755:CRES RS06550
gene id: 662755:CRES_RS06550
uniprot id: F8DYB7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

662755:CRES RS00700
gene id: 662755:CRES_RS00700
uniprot id: F8E141
names: Similarity
messages: Belongs to the SAICAR synthetase family.

662755:CRES RS04235
gene id: 662755:CRES_RS04235
uniprot id: F8E0D9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

662755:CRES RS04035
gene id: 662755:CRES_RS04035
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS07040
gene id: 662755:CRES_RS07040
uniprot id: F8DYX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS09360
gene id: 662755:CRES_RS09360
uniprot id: F8E1V4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

662755:CRES RS07200
gene id: 662755:CRES_RS07200
uniprot id: F8DZ64
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

662755:CRES RS01930
gene id: 662755:CRES_RS01930
uniprot id: F8DXT9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

662755:CRES RS03820
gene id: 662755:CRES_RS03820
uniprot id: F8DZP9
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS01855
gene id: 662755:CRES_RS01855
uniprot id: F8DXH5
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

662755:CRES RS05895
gene id: 662755:CRES_RS05895
uniprot id: F8DXJ5
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

662755:CRES RS08780
gene id: 662755:CRES_RS08780
uniprot id: F8E0X1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

662755:CRES RS03280
gene id: 662755:CRES_RS03280
uniprot id: F8DZ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

662755:CRES RS02150
gene id: 662755:CRES_RS02150
uniprot id: F8DY38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

662755:CRES RS09730
gene id: 662755:CRES_RS09730
uniprot id: F8E2C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

662755:CRES RS00635
gene id: 662755:CRES_RS00635
uniprot id: F8E128
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

662755:CRES RS09680
gene id: 662755:CRES_RS09680
uniprot id: F8E2B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

662755:CRES RS06305
gene id: 662755:CRES_RS06305
uniprot id: F8DY20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

662755:CRES RS05715
gene id: 662755:CRES_RS05715
uniprot id: F8E308
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS11285
gene id: 662755:CRES_RS11285
uniprot id: F8E3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

662755:CRES RS00725
gene id: 662755:CRES_RS00725
uniprot id: F8E1J0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

662755:CRES RS06165
gene id: 662755:CRES_RS06165
uniprot id: F8DXZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

662755:CRES RS04300
gene id: 662755:CRES_RS04300
uniprot id: F8E0F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS00525
gene id: 662755:CRES_RS00525
uniprot id: F8E112
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

662755:CRES RS04365
gene id: 662755:CRES_RS04365
uniprot id: F8E0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662755:CRES RS04110
gene id: 662755:CRES_RS04110
uniprot id: F8E016
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

662755:CRES RS07535
gene id: 662755:CRES_RS07535
uniprot id: F8DZJ7
names: Similarity
messages: Belongs to the peptidase M17 family.

662755:CRES RS10530
gene id: 662755:CRES_RS10530
uniprot id: F8DXQ3
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05785
gene id: 662755:CRES_RS05785
uniprot id: F8E322
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS09155
gene id: 662755:CRES_RS09155
uniprot id: F8E1H5
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS03505
gene id: 662755:CRES_RS03505
uniprot id: F8DZE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

662755:CRES RS09910
gene id: 662755:CRES_RS09910
uniprot id: F8E2P8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

662755:CRES RS04840
gene id: 662755:CRES_RS04840
uniprot id: F8E0T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

662755:CRES RS02635
gene id: 662755:CRES_RS02635
uniprot id: F8DYM9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

662755:CRES RS03550
gene id: 662755:CRES_RS03550
uniprot id: F8DZF3
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS06585
gene id: 662755:CRES_RS06585
uniprot id: F8DYC4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662755:CRES RS03450
gene id: 662755:CRES_RS03450
uniprot id: F8DZD3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

662755:CRES RS09345
gene id: 662755:CRES_RS09345
uniprot id: F8E1V1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

662755:CRES RS09140
gene id: 662755:CRES_RS09140
uniprot id: F8E1H1
names: Similarity
messages: Belongs to the peptidase C40 family.

662755:CRES RS04835
gene id: 662755:CRES_RS04835
uniprot id: F8E0S9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

662755:CRES RS09050
gene id: 662755:CRES_RS09050
uniprot id: F8E1F2
names: Similarity
messages: Belongs to the AccD/PCCB family.

662755:CRES RS08310
gene id: 662755:CRES_RS08310
uniprot id: F8E0H1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

662755:CRES RS08200
gene id: 662755:CRES_RS08200
uniprot id: F8E069
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

662755:CRES RS02415
gene id: 662755:CRES_RS02415
uniprot id: F8DYD7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

662755:CRES RS04270
gene id: 662755:CRES_RS04270
uniprot id: F8E0E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

662755:CRES RS02175
gene id: 662755:CRES_RS02175
uniprot id: F8DY43
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

662755:CRES RS05475
gene id: 662755:CRES_RS05475
uniprot id: F8E2K7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

662755:CRES RS06920
gene id: 662755:CRES_RS06920
uniprot id: F8DYV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

662755:CRES RS03465
gene id: 662755:CRES_RS03465
uniprot id: F8DZD6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

662755:CRES RS00675
gene id: 662755:CRES_RS00675
uniprot id: F8E136
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

662755:CRES RS05330
gene id: 662755:CRES_RS05330
uniprot id: F8E275
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

662755:CRES RS06855
gene id: 662755:CRES_RS06855
uniprot id: F8DYL8
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS08445
gene id: 662755:CRES_RS08445
uniprot id: F8E0J7
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

662755:CRES RS05270
gene id: 662755:CRES_RS05270
uniprot id: F8E263
names: Similarity
messages: Belongs to the prokaryotic ubiquitin-like protein family.

662755:CRES RS03310
gene id: 662755:CRES_RS03310
uniprot id: F8DZ58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

662755:CRES RS00670
gene id: 662755:CRES_RS00670
uniprot id: F8E135
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

662755:CRES RS07395
gene id: 662755:CRES_RS07395
uniprot id: F8DZA3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

662755:CRES RS03070
gene id: 662755:CRES_RS03070
uniprot id: F8DZ16
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

662755:CRES RS03510
gene id: 662755:CRES_RS03510
uniprot id: F8DZE5
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS04260
gene id: 662755:CRES_RS04260
uniprot id: F8E0E4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

662755:CRES RS01475
gene id: 662755:CRES_RS01475
uniprot id: F8E2U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

662755:CRES RS07545
gene id: 662755:CRES_RS07545
uniprot id: F8DZJ9
names: Similarity
messages: Belongs to the LOG family.

662755:CRES RS01800
gene id: 662755:CRES_RS01800
uniprot id: F8DXG4
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05380
gene id: 662755:CRES_RS05380
uniprot id: F8E2I8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

662755:CRES RS07820
gene id: 662755:CRES_RS07820
uniprot id: F8DZV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

662755:CRES RS08225
gene id: 662755:CRES_RS08225
uniprot id: F8E074
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS00245
gene id: 662755:CRES_RS00245
uniprot id: F8E0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

662755:CRES RS07285
gene id: 662755:CRES_RS07285
uniprot id: F8DZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

662755:CRES RS08970
gene id: 662755:CRES_RS08970
uniprot id: F8E1D6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

662755:CRES RS09325
gene id: 662755:CRES_RS09325
uniprot id: F8E1U7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

662755:CRES RS03745
gene id: 662755:CRES_RS03745
uniprot id: F8DZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

662755:CRES RS09755
gene id: 662755:CRES_RS09755
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS04805
gene id: 662755:CRES_RS04805
uniprot id: F8E0S3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

662755:CRES RS05825
gene id: 662755:CRES_RS05825
uniprot id: F8E330
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

662755:CRES RS06365
gene id: 662755:CRES_RS06365
uniprot id: F8DY32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

662755:CRES RS04105
gene id: 662755:CRES_RS04105
uniprot id: F8E015
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

662755:CRES RS00875
gene id: 662755:CRES_RS00875
uniprot id: F8E1M0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

662755:CRES RS07065
gene id: 662755:CRES_RS07065
uniprot id: F8DYX8
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS00850
gene id: 662755:CRES_RS00850
uniprot id: F8E1L5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

662755:CRES RS05690
gene id: 662755:CRES_RS05690
uniprot id: F8E303
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

662755:CRES RS06710
gene id: 662755:CRES_RS06710
uniprot id: F8DYJ4
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

662755:CRES RS10585
gene id: 662755:CRES_RS10585
uniprot id: F8DXR4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

662755:CRES RS07390
gene id: 662755:CRES_RS07390
uniprot id: F8DZA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

662755:CRES RS05695
gene id: 662755:CRES_RS05695
uniprot id: F8E304
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

662755:CRES RS09475
gene id: 662755:CRES_RS09475
uniprot id: F8E1X6
names: Similarity
messages: Belongs to the WXG100 family.

662755:CRES RS10050
gene id: 662755:CRES_RS10050
uniprot id: F8E2S4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS03285
gene id: 662755:CRES_RS03285
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS09865
gene id: 662755:CRES_RS09865
uniprot id: F8E2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

662755:CRES RS10785
gene id: 662755:CRES_RS10785
uniprot id: F8E3B5
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05440
gene id: 662755:CRES_RS05440
uniprot id: F8E2K0
names: Similarity
messages: Belongs to the UPF0237 family.

662755:CRES RS06510
gene id: 662755:CRES_RS06510
uniprot id: F8DYA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

662755:CRES RS10205
gene id: 662755:CRES_RS10205
uniprot id: F8E354
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

662755:CRES RS06500
gene id: 662755:CRES_RS06500
uniprot id: F8DYA6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

662755:CRES RS07845
gene id: 662755:CRES_RS07845
uniprot id: F8DZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

662755:CRES RS08605
gene id: 662755:CRES_RS08605
uniprot id: F8E0T9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

662755:CRES RS10285
gene id: 662755:CRES_RS10285
uniprot id: F8E371
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS09575
gene id: 662755:CRES_RS09575
uniprot id: F8E290
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

662755:CRES RS04065
gene id: 662755:CRES_RS04065
uniprot id: F8E007
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

662755:CRES RS05640
gene id: 662755:CRES_RS05640
uniprot id: F8E2Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS02130
gene id: 662755:CRES_RS02130
uniprot id: F8DXX9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

662755:CRES RS05410
gene id: 662755:CRES_RS05410
uniprot id: F8E2J4
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

662755:CRES RS01655
gene id: 662755:CRES_RS01655
uniprot id: F8E2Y2
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS00460
gene id: 662755:CRES_RS00460
uniprot id: F8E103
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

662755:CRES RS06285
gene id: 662755:CRES_RS06285
uniprot id: F8DY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

662755:CRES RS03950
gene id: 662755:CRES_RS03950
uniprot id: F8DZY4
names: Similarity
messages: Belongs to the peptidase C40 family.

662755:CRES RS02425
gene id: 662755:CRES_RS02425
uniprot id: F8DYD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

662755:CRES RS02255
gene id: 662755:CRES_RS02255
uniprot id: F8DY59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662755:CRES RS10465
gene id: 662755:CRES_RS10465
uniprot id: F8DXP1
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

662755:CRES RS06775
gene id: 662755:CRES_RS06775
uniprot id: F8DYK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

662755:CRES RS10105
gene id: 662755:CRES_RS10105
uniprot id: F8E2T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

662755:CRES RS03590
gene id: 662755:CRES_RS03590
uniprot id: F8DZG2
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

662755:CRES RS02135
gene id: 662755:CRES_RS02135
uniprot id: F8DXY0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

662755:CRES RS03665
gene id: 662755:CRES_RS03665
uniprot id: F8DZM0
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

662755:CRES RS07775
gene id: 662755:CRES_RS07775
uniprot id: F8DZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

662755:CRES RS10730
gene id: 662755:CRES_RS10730
uniprot id: F8E3A5
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

662755:CRES RS10460
gene id: 662755:CRES_RS10460
uniprot id: F8DXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Membrane

662755:CRES RS00290
gene id: 662755:CRES_RS00290
uniprot id: F8E0P4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

662755:CRES RS05265
gene id: 662755:CRES_RS05265
uniprot id: F8E262
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

662755:CRES RS03915
gene id: 662755:CRES_RS03915
uniprot id: F8DZR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS06810
gene id: 662755:CRES_RS06810
uniprot id: F8DYL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

662755:CRES RS04125
gene id: 662755:CRES_RS04125
uniprot id: F8E019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

662755:CRES RS06540
gene id: 662755:CRES_RS06540
uniprot id: F8DYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

662755:CRES RS09520
gene id: 662755:CRES_RS09520
uniprot id: F8E1Y4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

662755:CRES RS09705
gene id: 662755:CRES_RS09705
uniprot id: F8E2B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

662755:CRES RS10650
gene id: 662755:CRES_RS10650
uniprot id: F8DXS9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

662755:CRES RS01535
gene id: 662755:CRES_RS01535
uniprot id: F8E2V8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

662755:CRES RS00595
gene id: 662755:CRES_RS00595
uniprot id: F8E120
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

662755:CRES RS06625
gene id: 662755:CRES_RS06625
uniprot id: F8DYD2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

662755:CRES RS05140
gene id: 662755:CRES_RS05140
uniprot id: F8E236
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

662755:CRES RS03010
gene id: 662755:CRES_RS03010
uniprot id: F8DZ05
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

662755:CRES RS05470
gene id: 662755:CRES_RS05470
uniprot id: F8E2K6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

662755:CRES RS07370
gene id: 662755:CRES_RS07370
uniprot id: F8DZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

662755:CRES RS01905
gene id: 662755:CRES_RS01905
uniprot id: F8DXT4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662755:CRES RS03965
gene id: 662755:CRES_RS03965
uniprot id: F8DZY7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

662755:CRES RS04460
gene id: 662755:CRES_RS04460
uniprot id: F8E160
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05090
gene id: 662755:CRES_RS05090
uniprot id: F8E1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

662755:CRES RS09955
gene id: 662755:CRES_RS09955
uniprot id: F8E2Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

662755:CRES RS00685
gene id: 662755:CRES_RS00685
uniprot id: F8E138
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

662755:CRES RS08685
gene id: 662755:CRES_RS08685
uniprot id: F8E0V5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

662755:CRES RS03230
gene id: 662755:CRES_RS03230
uniprot id: F8DZ42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

662755:CRES RS03910
gene id: 662755:CRES_RS03910
uniprot id: F8DZR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

662755:CRES RS07085
gene id: 662755:CRES_RS07085
uniprot id: F8DYY2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

662755:CRES RS04325
gene id: 662755:CRES_RS04325
uniprot id: F8E0F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

662755:CRES RS04710
gene id: 662755:CRES_RS04710
uniprot id: F8E1A6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

662755:CRES RS04865
gene id: 662755:CRES_RS04865
uniprot id: F8E0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

662755:CRES RS06400
gene id: 662755:CRES_RS06400
uniprot id: F8DY86
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

662755:CRES RS09220
gene id: 662755:CRES_RS09220
uniprot id: F8E1I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

662755:CRES RS07715
gene id: 662755:CRES_RS07715
uniprot id: F8DZT7
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS09200
gene id: 662755:CRES_RS09200
uniprot id: F8E1I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

662755:CRES RS08415
gene id: 662755:CRES_RS08415
uniprot id: F8E0J1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS08815
gene id: 662755:CRES_RS08815
uniprot id: F8E0X8
names: Similarity
messages: Belongs to the DEAD box helicase family.

662755:CRES RS04150
gene id: 662755:CRES_RS04150
uniprot id: F8E024
names: Similarity
messages: Belongs to the asparaginase 1 family.

662755:CRES RS04570
gene id: 662755:CRES_RS04570
uniprot id: F8E182
names: Similarity
messages: Belongs to the AdoMet synthase family.

662755:CRES RS04875
gene id: 662755:CRES_RS04875
uniprot id: F8E1N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

662755:CRES RS09740
gene id: 662755:CRES_RS09740
uniprot id: F8E2C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

662755:CRES RS09855
gene id: 662755:CRES_RS09855
uniprot id: F8E2P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

662755:CRES RS11410
gene id: 662755:CRES_RS11410
uniprot id: F8DY44
names: Similarity
messages: Belongs to the heat shock protein 70 family.

662755:CRES RS07595
gene id: 662755:CRES_RS07595
uniprot id: F8DZK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

662755:CRES RS04790
gene id: 662755:CRES_RS04790
uniprot id: F8E1C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

662755:CRES RS01750
gene id: 662755:CRES_RS01750
uniprot id: F8DXF4
names: Similarity
messages: Belongs to the citrate synthase family.

662755:CRES RS02345
gene id: 662755:CRES_RS02345
uniprot id: F8DY75
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

662755:CRES RS03490
gene id: 662755:CRES_RS03490
uniprot id: F8DZE1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

662755:CRES RS10810
gene id: 662755:CRES_RS10810
uniprot id: F8E3B9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

662755:CRES RS07945
gene id: 662755:CRES_RS07945
uniprot id: F8DZY0
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

662755:CRES RS05515
gene id: 662755:CRES_RS05515
uniprot id: F8E2L5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

662755:CRES RS09380
gene id: 662755:CRES_RS09380
uniprot id: F8E1V8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

662755:CRES RS01075
gene id: 662755:CRES_RS01075
uniprot id: F8E212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

662755:CRES RS01595
gene id: 662755:CRES_RS01595
uniprot id: F8E2X0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

662755:CRES RS06595
gene id: 662755:CRES_RS06595
uniprot id: F8DYC6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

662755:CRES RS06075
gene id: 662755:CRES_RS06075
uniprot id: F8DXM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

662755:CRES RS10525
gene id: 662755:CRES_RS10525
uniprot id: F8DXQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662755:CRES RS03625
gene id: 662755:CRES_RS03625
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS02155
gene id: 662755:CRES_RS02155
uniprot id: F8DY39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

662755:CRES RS00590
gene id: 662755:CRES_RS00590
uniprot id: F8E119
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

662755:CRES RS01900
gene id: 662755:CRES_RS01900
uniprot id: F8DXI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

662755:CRES RS06990
gene id: 662755:CRES_RS06990
uniprot id: F8DYW2
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS08755
gene id: 662755:CRES_RS08755
uniprot id: F8E0W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

662755:CRES RS02725
gene id: 662755:CRES_RS02725
uniprot id: F8DYP7
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

662755:CRES RS03795
gene id: 662755:CRES_RS03795
uniprot id: F8DZP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

662755:CRES RS02045
gene id: 662755:CRES_RS02045
uniprot id: F8DXW2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

662755:CRES RS09780
gene id: 662755:CRES_RS09780
uniprot id: F8E2D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

662755:CRES RS04780
gene id: 662755:CRES_RS04780
uniprot id: F8E1C0
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS06440
gene id: 662755:CRES_RS06440
uniprot id: F8DY94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

662755:CRES RS06695
gene id: 662755:CRES_RS06695
uniprot id: F8DYJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

662755:CRES RS06930
gene id: 662755:CRES_RS06930
uniprot id: F8DYV2
names: Subcellular Location Annotation
messages: Secreted

662755:CRES RS07585
gene id: 662755:CRES_RS07585
uniprot id: F8DZK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

662755:CRES RS10230
gene id: 662755:CRES_RS10230
uniprot id: F8E359
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

662755:CRES RS02585
gene id: 662755:CRES_RS02585
uniprot id: F8DYG8
names: Similarity
messages: Belongs to the universal stress protein A family.

662755:CRES RS00860
gene id: 662755:CRES_RS00860
uniprot id: F8E1L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

662755:CRES RS08645
gene id: 662755:CRES_RS08645
uniprot id: F8E0U7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

662755:CRES RS06555
gene id: 662755:CRES_RS06555
uniprot id: F8DYB8
names: Similarity
messages: Belongs to the UPF0102 family.

662755:CRES RS05150
gene id: 662755:CRES_RS05150
uniprot id: F8E238
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

662755:CRES RS04090
gene id: 662755:CRES_RS04090
uniprot id: F8E012
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

662755:CRES RS09590
gene id: 662755:CRES_RS09590
uniprot id: F8E293
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

662755:CRES RS05565
gene id: 662755:CRES_RS05565
uniprot id: F8E2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

662755:CRES RS08615
gene id: 662755:CRES_RS08615
uniprot id: F8E0U1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

662755:CRES RS03845
gene id: 662755:CRES_RS03845
uniprot id: F8DZQ4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

662755:CRES RS01520
gene id: 662755:CRES_RS01520
uniprot id: F8E2V5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS03760
gene id: 662755:CRES_RS03760
uniprot id: F8DZN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS01580
gene id: 662755:CRES_RS01580
uniprot id: F8E2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

662755:CRES RS09460
gene id: 662755:CRES_RS09460
uniprot id: F8E1X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

662755:CRES RS05540
gene id: 662755:CRES_RS05540
uniprot id: F8E2M0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

662755:CRES RS03765
gene id: 662755:CRES_RS03765
uniprot id: F8DZN9
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS07080
gene id: 662755:CRES_RS07080
uniprot id: F8DYY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

662755:CRES RS04860
gene id: 662755:CRES_RS04860
uniprot id: F8E0T4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS09015
gene id: 662755:CRES_RS09015
uniprot id: F8E1E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

662755:CRES RS07145
gene id: 662755:CRES_RS07145
uniprot id: F8DYZ4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

662755:CRES RS09720
gene id: 662755:CRES_RS09720
uniprot id: F8E2B9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

662755:CRES RS03240
gene id: 662755:CRES_RS03240
uniprot id: F8DZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

662755:CRES RS00680
gene id: 662755:CRES_RS00680
uniprot id: F8E137
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

662755:CRES RS01725
gene id: 662755:CRES_RS01725
uniprot id: F8DXE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

662755:CRES RS00710
gene id: 662755:CRES_RS00710
uniprot id: F8E143
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

662755:CRES RS08885
gene id: 662755:CRES_RS08885
uniprot id: F8E0Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

662755:CRES RS06605
gene id: 662755:CRES_RS06605
uniprot id: F8DYC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

662755:CRES RS03425
gene id: 662755:CRES_RS03425
uniprot id: F8DZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

662755:CRES RS01190
gene id: 662755:CRES_RS01190
uniprot id: F8E2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

662755:CRES RS04280
gene id: 662755:CRES_RS04280
uniprot id: F8E0E8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

662755:CRES RS10740
gene id: 662755:CRES_RS10740
uniprot id: F8E3A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

662755:CRES RS06645
gene id: 662755:CRES_RS06645
uniprot id: F8DYI1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

662755:CRES RS01060
gene id: 662755:CRES_RS01060
uniprot id: F8E209
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662755:CRES RS03840
gene id: 662755:CRES_RS03840
uniprot id: F8DZQ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

662755:CRES RS00365
gene id: 662755:CRES_RS00365
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS00255
gene id: 662755:CRES_RS00255
uniprot id: F8E0N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS00655
gene id: 662755:CRES_RS00655
uniprot id: F8E132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

662755:CRES RS08210
gene id: 662755:CRES_RS08210
uniprot id: F8E071
names: Similarity
messages: Belongs to the FBPase class 2 family.

662755:CRES RS11175
gene id: 662755:CRES_RS11175
uniprot id: F8E3I6
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS08010
gene id: 662755:CRES_RS08010
uniprot id: F8E033
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

662755:CRES RS08180
gene id: 662755:CRES_RS08180
uniprot id: F8E065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

662755:CRES RS04180
gene id: 662755:CRES_RS04180
uniprot id: F8E0C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

662755:CRES RS05205
gene id: 662755:CRES_RS05205
uniprot id: F8E250
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS08565
gene id: 662755:CRES_RS08565
uniprot id: F8E0M1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

662755:CRES RS10995
gene id: 662755:CRES_RS10995
uniprot id: F8E3F3
names: Similarity
messages: Belongs to the thioredoxin family.

662755:CRES RS05700
gene id: 662755:CRES_RS05700
uniprot id: F8E305
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

662755:CRES RS05840
gene id: 662755:CRES_RS05840
uniprot id: F8E333
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

662755:CRES RS09115
gene id: 662755:CRES_RS09115
uniprot id: F8E1G6
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

662755:CRES RS05710
gene id: 662755:CRES_RS05710
uniprot id: F8E307
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

662755:CRES RS04305
gene id: 662755:CRES_RS04305
uniprot id: F8E0F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

662755:CRES RS09715
gene id: 662755:CRES_RS09715
uniprot id: F8E2B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

662755:CRES RS06375
gene id: 662755:CRES_RS06375
uniprot id: F8DY33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

662755:CRES RS02120
gene id: 662755:CRES_RS02120
uniprot id: F8DXX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

662755:CRES RS09985
gene id: 662755:CRES_RS09985
uniprot id: F8E2R2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

662755:CRES RS04335
gene id: 662755:CRES_RS04335
uniprot id: F8E0F9
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

662755:CRES RS01100
gene id: 662755:CRES_RS01100
uniprot id: F8E217
names: Similarity
messages: Belongs to the Nth/MutY family.

662755:CRES RS04080
gene id: 662755:CRES_RS04080
uniprot id: F8E010
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05675
gene id: 662755:CRES_RS05675
uniprot id: F8E300
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

662755:CRES RS05525
gene id: 662755:CRES_RS05525
uniprot id: F8E2L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

662755:CRES RS07365
gene id: 662755:CRES_RS07365
uniprot id: F8DZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

662755:CRES RS04060
gene id: 662755:CRES_RS04060
uniprot id: F8E006
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS03695
gene id: 662755:CRES_RS03695
uniprot id: F8DZM5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

662755:CRES RS07075
gene id: 662755:CRES_RS07075
uniprot id: F8DYY0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS00345
gene id: 662755:CRES_RS00345
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS03440
gene id: 662755:CRES_RS03440
uniprot id: F8DZD1
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS11465
gene id: 662755:CRES_RS11465
uniprot id: F8DZR1
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05650
gene id: 662755:CRES_RS05650
uniprot id: F8E2Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

662755:CRES RS04850
gene id: 662755:CRES_RS04850
uniprot id: F8E0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

662755:CRES RS08260
gene id: 662755:CRES_RS08260
uniprot id: F8E080
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662755:CRES RS05805
gene id: 662755:CRES_RS05805
uniprot id: F8E326
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS05485
gene id: 662755:CRES_RS05485
uniprot id: F8E2K9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

662755:CRES RS03265
gene id: 662755:CRES_RS03265
uniprot id: F8DZ49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

662755:CRES RS01050
gene id: 662755:CRES_RS01050
uniprot id: F8E207
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS06470
gene id: 662755:CRES_RS06470
uniprot id: F8DYA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

662755:CRES RS10390
gene id: 662755:CRES_RS10390
uniprot id: F8E392
names: Subcellular Location Annotation
messages: Cytoplasm

662755:CRES RS10330
gene id: 662755:CRES_RS10330
uniprot id: F8E381
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS10625
gene id: 662755:CRES_RS10625
uniprot id: F8DXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

662755:CRES RS10240
gene id: 662755:CRES_RS10240
uniprot id: F8E361
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

662755:CRES RS01835
gene id: 662755:CRES_RS01835
uniprot id: F8DXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

662755:CRES RS07315
gene id: 662755:CRES_RS07315
uniprot id: F8DZ88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

662755:CRES RS07375
gene id: 662755:CRES_RS07375
uniprot id: F8DZA0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

662755:CRES RS09170
gene id: 662755:CRES_RS09170
uniprot id: F8E1H8
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS10895
gene id: 662755:CRES_RS10895
uniprot id: F8E3D3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

662755:CRES RS08420
gene id: 662755:CRES_RS08420
uniprot id: F8E0J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

662755:CRES RS10950
gene id: 662755:CRES_RS10950
uniprot id: F8E3E4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS02145
gene id: 662755:CRES_RS02145
uniprot id: F8DY37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

662755:CRES RS02870
gene id: 662755:CRES_RS02870
uniprot id: F8DYS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

662755:CRES RS08625
gene id: 662755:CRES_RS08625
uniprot id: F8E0U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

662755:CRES RS00985
gene id: 662755:CRES_RS00985
uniprot id: F8E1Z4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

662755:CRES RS03170
gene id: 662755:CRES_RS03170
uniprot id: F8DZ32
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

662755:CRES RS09710
gene id: 662755:CRES_RS09710
uniprot id: F8E2B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

662755:CRES RS03330
gene id: 662755:CRES_RS03330
uniprot id: F8DZA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

662755:CRES RS11160
gene id: 662755:CRES_RS11160
uniprot id: F8E3I3
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS09585
gene id: 662755:CRES_RS09585
uniprot id: F8E292
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

662755:CRES RS01500
gene id: 662755:CRES_RS01500
uniprot id: F8E2V1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

662755:CRES RS01950
gene id: 662755:CRES_RS01950
uniprot id: F8DXU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

662755:CRES RS08665
gene id: 662755:CRES_RS08665
uniprot id: F8E0V1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662755:CRES RS08895
gene id: 662755:CRES_RS08895
uniprot id: F8E0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

662755:CRES RS03385
gene id: 662755:CRES_RS03385
uniprot id: F8DZC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

662755:CRES RS09165
gene id: 662755:CRES_RS09165
uniprot id: F8E1H7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

662755:CRES RS05305
gene id: 662755:CRES_RS05305
uniprot id: F8E270
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

662755:CRES RS06935
gene id: 662755:CRES_RS06935
uniprot id: F8DYV3
names: Subcellular Location Annotation
messages: Secreted

662755:CRES RS07275
gene id: 662755:CRES_RS07275
uniprot id: F8DZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

662755:CRES RS00950
gene id: 662755:CRES_RS00950
uniprot id: F8E1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

662755:CRES RS11245
gene id: 662755:CRES_RS11245
uniprot id: F8E3K0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

662755:CRES RS07165
gene id: 662755:CRES_RS07165
uniprot id: F8DYZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

662755:CRES RS06480
gene id: 662755:CRES_RS06480
uniprot id: F8DYA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS04760
gene id: 662755:CRES_RS04760
uniprot id: F8E1B6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

662755:CRES RS08060
gene id: 662755:CRES_RS08060
uniprot id: F8E043
names: Similarity
messages: Belongs to the peptidase S14 family.

662755:CRES RS06310
gene id: 662755:CRES_RS06310
uniprot id: F8DY21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

662755:CRES RS03145
gene id: 662755:CRES_RS03145
uniprot id: F8DZ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

662755:CRES RS10380
gene id: 662755:CRES_RS10380
uniprot id: F8E390
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

662755:CRES RS09525
gene id: 662755:CRES_RS09525
uniprot id: F8E1Y5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

662755:CRES RS10555
gene id: 662755:CRES_RS10555
uniprot id: F8DXQ8
names: Similarity
messages: Belongs to the OsmC/Ohr family.

662755:CRES RS06675
gene id: 662755:CRES_RS06675
uniprot id: F8DYI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

662755:CRES RS06210
gene id: 662755:CRES_RS06210
uniprot id: F8DY01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

662755:CRES RS10430
gene id: 662755:CRES_RS10430
uniprot id: F8DXN4
names: Similarity
messages: Belongs to the GSP E family.

662755:CRES RS05050
gene id: 662755:CRES_RS05050
uniprot id: F8E1R9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

662755:CRES RS04755
gene id: 662755:CRES_RS04755
uniprot id: F8E1B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

662755:CRES RS06615
gene id: 662755:CRES_RS06615
uniprot id: F8DYD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

662755:CRES RS04040
gene id: 662755:CRES_RS04040
uniprot id: F8E002
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

662755:CRES RS01785
gene id: 662755:CRES_RS01785
uniprot id: F8DXG1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

662755:CRES RS10340
gene id: 662755:CRES_RS10340
uniprot id: F8E383
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

662755:CRES RS11105
gene id: 662755:CRES_RS11105
uniprot id: F8E3H1
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS09880
gene id: 662755:CRES_RS09880
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS01795
gene id: 662755:CRES_RS01795
uniprot id: F8DXG3
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS07255
gene id: 662755:CRES_RS07255
uniprot id: F8DZ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

662755:CRES RS01220
gene id: 662755:CRES_RS01220
uniprot id: F8E2E9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

662755:CRES RS07870
gene id: 662755:CRES_RS07870
uniprot id: F8DZW6
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS00160
gene id: 662755:CRES_RS00160
uniprot id: F8E0B8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

662755:CRES RS08270
gene id: 662755:CRES_RS08270
uniprot id: F8E082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

662755:CRES RS10560
gene id: 662755:CRES_RS10560
uniprot id: F8DXQ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

662755:CRES RS02645
gene id: 662755:CRES_RS02645
uniprot id: F8DYN1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

662755:CRES RS09030
gene id: 662755:CRES_RS09030
uniprot id: F8E1E8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

662755:CRES RS02245
gene id: 662755:CRES_RS02245
uniprot id: F8DY57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

662755:CRES RS08795
gene id: 662755:CRES_RS08795
uniprot id: F8E0X4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

662755:CRES RS03245
gene id: 662755:CRES_RS03245
uniprot id: F8DZ45
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

662755:CRES RS07575
gene id: 662755:CRES_RS07575
uniprot id: F8DZK5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

662755:CRES RS05555
gene id: 662755:CRES_RS05555
uniprot id: F8E2M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

662755:CRES RS01020
gene id: 662755:CRES_RS01020
uniprot id: F8E201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

662755:CRES RS04645
gene id: 662755:CRES_RS04645
uniprot id: F8E195
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

662755:CRES RS10370
gene id: 662755:CRES_RS10370
uniprot id: F8E388
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

662755:CRES RS10890
gene id: 662755:CRES_RS10890
uniprot id: F8E3D2
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS10640
gene id: 662755:CRES_RS10640
uniprot id: F8DXS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

662755:CRES RS03455
gene id: 662755:CRES_RS03455
uniprot id: F8DZD4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

662755:CRES RS00185
gene id: 662755:CRES_RS00185
uniprot id: F8E0C3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

662755:CRES RS11040
gene id: 662755:CRES_RS11040
uniprot id: F8E3G1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS06300
gene id: 662755:CRES_RS06300
uniprot id: F8DY19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

662755:CRES RS10565
gene id: 662755:CRES_RS10565
uniprot id: F8DXR0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

662755:CRES RS06250
gene id: 662755:CRES_RS06250
uniprot id: F8DY09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

662755:CRES RS05740
gene id: 662755:CRES_RS05740
uniprot id: F8E313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

662755:CRES RS10935
gene id: 662755:CRES_RS10935
uniprot id: F8E3E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

662755:CRES RS03895
gene id: 662755:CRES_RS03895
uniprot id: F8DZR4
names: Similarity
messages: Belongs to the asparagine synthetase family.

662755:CRES RS10685
gene id: 662755:CRES_RS10685
uniprot id: F8E396
names: Similarity
messages: Belongs to the peptidase C56 family.

662755:CRES RS03860
gene id: 662755:CRES_RS03860
uniprot id: F8DZQ7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

662755:CRES RS09735
gene id: 662755:CRES_RS09735
uniprot id: F8E2C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

662755:CRES RS10385
gene id: 662755:CRES_RS10385
uniprot id: F8E391
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

662755:CRES RS10945
gene id: 662755:CRES_RS10945
uniprot id: F8E3E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

662755:CRES RS08690
gene id: 662755:CRES_RS08690
uniprot id: F8E0V6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS02030
gene id: 662755:CRES_RS02030
uniprot id: F8DXW0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

662755:CRES RS06530
gene id: 662755:CRES_RS06530
uniprot id: F8DYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

662755:CRES RS03090
gene id: 662755:CRES_RS03090
uniprot id: F8E0Q5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

662755:CRES RS05345
gene id: 662755:CRES_RS05345
uniprot id: F8E278
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

662755:CRES RS08845
gene id: 662755:CRES_RS08845
uniprot id: F8E0Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

662755:CRES RS10980
gene id: 662755:CRES_RS10980
uniprot id: F8E3F0
names: Subcellular Location Annotation
messages: Membrane

662755:CRES RS05845
gene id: 662755:CRES_RS05845
uniprot id: F8E334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

662755:CRES RS05725
gene id: 662755:CRES_RS05725
uniprot id: F8E310
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

662755:CRES RS01745
gene id: 662755:CRES_RS01745
uniprot id: F8DXF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

662755:CRES RS04920
gene id: 662755:CRES_RS04920
uniprot id: F8E1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane