660470:THEBA RS05645
gene id: 660470:THEBA_RS05645
uniprot id: I2F4G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

660470:THEBA RS10020
gene id: 660470:THEBA_RS10020
uniprot id: I2F6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07995
gene id: 660470:THEBA_RS07995
uniprot id: I2F5Q0
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS13675
gene id: 660470:THEBA_RS13675
uniprot id: I2F8S6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

660470:THEBA RS03670
gene id: 660470:THEBA_RS03670
uniprot id: I2F3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

660470:THEBA RS02195
gene id: 660470:THEBA_RS02195
uniprot id: I2F2I6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

660470:THEBA RS02515
gene id: 660470:THEBA_RS02515
uniprot id: I2F2P9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

660470:THEBA RS07405
gene id: 660470:THEBA_RS07405
uniprot id: I2F5E5
names: Similarity
messages: Belongs to the peptidase S41A family.

660470:THEBA RS04505
gene id: 660470:THEBA_RS04505
uniprot id: I2F3U2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

660470:THEBA RS13635
gene id: 660470:THEBA_RS13635
uniprot id: I2F8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS09195
gene id: 660470:THEBA_RS09195
uniprot id: I2F6C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

660470:THEBA RS02520
gene id: 660470:THEBA_RS02520
uniprot id: I2F2Q0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

660470:THEBA RS01320
gene id: 660470:THEBA_RS01320
uniprot id: I2F218
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

660470:THEBA RS04065
gene id: 660470:THEBA_RS04065
uniprot id: I2F3K2
names: Similarity
messages: Belongs to the asparaginase 1 family.

660470:THEBA RS07780
gene id: 660470:THEBA_RS07780
uniprot id: I2F5L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

660470:THEBA RS13590
gene id: 660470:THEBA_RS13590
uniprot id: I2F8R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

660470:THEBA RS03345
gene id: 660470:THEBA_RS03345
uniprot id: I2F360
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

660470:THEBA RS13640
gene id: 660470:THEBA_RS13640
uniprot id: I2F8S1
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

660470:THEBA RS13415
gene id: 660470:THEBA_RS13415
uniprot id: I2F8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

660470:THEBA RS04875
gene id: 660470:THEBA_RS04875
uniprot id: I2F412
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

660470:THEBA RS05425
gene id: 660470:THEBA_RS05425
uniprot id: I2F4B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS03040
gene id: 660470:THEBA_RS03040
uniprot id: I2F2Z8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

660470:THEBA RS08630
gene id: 660470:THEBA_RS08630
uniprot id: I2F620
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

660470:THEBA RS00495
gene id: 660470:THEBA_RS00495
uniprot id: I2F1M4
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

660470:THEBA RS02930
gene id: 660470:THEBA_RS02930
uniprot id: I2F2X9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

660470:THEBA RS11100
gene id: 660470:THEBA_RS11100
uniprot id: I2F7F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

660470:THEBA RS00170
gene id: 660470:THEBA_RS00170
uniprot id: I2F1G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

660470:THEBA RS13670
gene id: 660470:THEBA_RS13670
uniprot id: I2F8S5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

660470:THEBA RS12290
gene id: 660470:THEBA_RS12290
uniprot id: I2F827
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

660470:THEBA RS03490
gene id: 660470:THEBA_RS03490
uniprot id: I2F389
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

660470:THEBA RS04690
gene id: 660470:THEBA_RS04690
uniprot id: I2F3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS01820
gene id: 660470:THEBA_RS01820
uniprot id: I2F2B1
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04475
gene id: 660470:THEBA_RS04475
uniprot id: I2F3T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

660470:THEBA RS11470
gene id: 660470:THEBA_RS11470
uniprot id: I2F7N0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

660470:THEBA RS04180
gene id: 660470:THEBA_RS04180
uniprot id: I2F3M6
names: Similarity
messages: Belongs to the CTP synthase family.

660470:THEBA RS12780
gene id: 660470:THEBA_RS12780
uniprot id: I2F8A9
names: Subcellular Location Annotation
messages: Cytoplasm

660470:THEBA RS02905
gene id: 660470:THEBA_RS02905
uniprot id: I2F2X4
names: Similarity
messages: Belongs to the fabD family.

660470:THEBA RS00615
gene id: 660470:THEBA_RS00615
uniprot id: I2F1P5
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06880
gene id: 660470:THEBA_RS06880
uniprot id: I2F545
names: Similarity
messages: Belongs to the peptidase S9C family.

660470:THEBA RS05140
gene id: 660470:THEBA_RS05140
uniprot id: I2F462
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS00490
gene id: 660470:THEBA_RS00490
uniprot id: I2F1M3
names: Similarity
messages: Belongs to the catalase family.

660470:THEBA RS02500
gene id: 660470:THEBA_RS02500
uniprot id: I2F2P6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

660470:THEBA RS06270
gene id: 660470:THEBA_RS06270
uniprot id: I2F4S6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

660470:THEBA RS08700
gene id: 660470:THEBA_RS08700
uniprot id: I2F5W3
names: Similarity
messages: Belongs to the BtpA family.

660470:THEBA RS01325
gene id: 660470:THEBA_RS01325
uniprot id: I2F219
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

660470:THEBA RS00350
gene id: 660470:THEBA_RS00350
uniprot id: I2F1J6
names: Similarity
messages: Belongs to the peptidase U62 family.

660470:THEBA RS04300
gene id: 660470:THEBA_RS04300
uniprot id: I2F3P9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

660470:THEBA RS13185
gene id: 660470:THEBA_RS13185
uniprot id: I2F8I6
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS13465
gene id: 660470:THEBA_RS13465
uniprot id: I2F8P0
names: Similarity
messages: Belongs to the RutC family.

660470:THEBA RS03445
gene id: 660470:THEBA_RS03445
uniprot id: I2F380
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

660470:THEBA RS10615
gene id: 660470:THEBA_RS10615
uniprot id: I2F757
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

660470:THEBA RS08830
gene id: 660470:THEBA_RS08830
uniprot id: I2F659
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

660470:THEBA RS10070
gene id: 660470:THEBA_RS10070
uniprot id: I2F6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

660470:THEBA RS09185
gene id: 660470:THEBA_RS09185
uniprot id: I2F6C6
names: Similarity
messages: Belongs to the chorismate synthase family.

660470:THEBA RS02165
gene id: 660470:THEBA_RS02165
uniprot id: I2F2I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS03980
gene id: 660470:THEBA_RS03980
uniprot id: I2F3I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

660470:THEBA RS03415
gene id: 660470:THEBA_RS03415
uniprot id: I2F374
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

660470:THEBA RS04210
gene id: 660470:THEBA_RS04210
uniprot id: I2F3N1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

660470:THEBA RS02450
gene id: 660470:THEBA_RS02450
uniprot id: I2F2N6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

660470:THEBA RS09230
gene id: 660470:THEBA_RS09230
uniprot id: I2F6D5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

660470:THEBA RS10895
gene id: 660470:THEBA_RS10895
uniprot id: I2F7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS04615
gene id: 660470:THEBA_RS04615
uniprot id: I2F3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

660470:THEBA RS08510
gene id: 660470:THEBA_RS08510
uniprot id: I2F660
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

660470:THEBA RS00260
gene id: 660470:THEBA_RS00260
uniprot id: I2F1I1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

660470:THEBA RS00850
gene id: 660470:THEBA_RS00850
uniprot id: I2F1U1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

660470:THEBA RS07500
gene id: 660470:THEBA_RS07500
uniprot id: I2F5G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

660470:THEBA RS11645
gene id: 660470:THEBA_RS11645
uniprot id: I2F7R4
names: Similarity
messages: Belongs to the peptidase S16 family.

660470:THEBA RS01210
gene id: 660470:THEBA_RS01210
uniprot id: I2F1Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS05135
gene id: 660470:THEBA_RS05135
uniprot id: I2F461
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

660470:THEBA RS09950
gene id: 660470:THEBA_RS09950
uniprot id: I2F6S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

660470:THEBA RS05265
gene id: 660470:THEBA_RS05265
uniprot id: I2F485
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

660470:THEBA RS03940
gene id: 660470:THEBA_RS03940
uniprot id: I2F3H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

660470:THEBA RS05085
gene id: 660470:THEBA_RS05085
uniprot id: I2F452
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS08565
gene id: 660470:THEBA_RS08565
uniprot id: I2F606
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS03825
gene id: 660470:THEBA_RS03825
uniprot id: I2F3F5
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08250
gene id: 660470:THEBA_RS08250
uniprot id: I2F620
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

660470:THEBA RS05315
gene id: 660470:THEBA_RS05315
uniprot id: I2F495
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

660470:THEBA RS11995
gene id: 660470:THEBA_RS11995
uniprot id: I2F7X4
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS12065
gene id: 660470:THEBA_RS12065
uniprot id: I2F7Y8
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06605
gene id: 660470:THEBA_RS06605
uniprot id: I2F4Z2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01685
gene id: 660470:THEBA_RS01685
uniprot id: I2F286
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

660470:THEBA RS10075
gene id: 660470:THEBA_RS10075
uniprot id: I2F6U7
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

660470:THEBA RS07940
gene id: 660470:THEBA_RS07940
uniprot id: I2F5P1
names: Similarity
messages: Belongs to the peptidase S58 family.

660470:THEBA RS12270
gene id: 660470:THEBA_RS12270
uniprot id: I2F823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS03565
gene id: 660470:THEBA_RS03565
uniprot id: I2F3A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

660470:THEBA RS04325
gene id: 660470:THEBA_RS04325
uniprot id: I2F3Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

660470:THEBA RS03560
gene id: 660470:THEBA_RS03560
uniprot id: I2F3A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

660470:THEBA RS13665
gene id: 660470:THEBA_RS13665
uniprot id: I2F8S4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

660470:THEBA RS02380
gene id: 660470:THEBA_RS02380
uniprot id: I2F2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS01575
gene id: 660470:THEBA_RS01575
uniprot id: I2F266
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

660470:THEBA RS02095
gene id: 660470:THEBA_RS02095
uniprot id: I2F2G5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

660470:THEBA RS10965
gene id: 660470:THEBA_RS10965
uniprot id: I2F7D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

660470:THEBA RS03045
gene id: 660470:THEBA_RS03045
uniprot id: I2F2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

660470:THEBA RS03255
gene id: 660470:THEBA_RS03255
uniprot id: I2F343
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06720
gene id: 660470:THEBA_RS06720
uniprot id: I2F514
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

660470:THEBA RS05715
gene id: 660470:THEBA_RS05715
uniprot id: I2F4H2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04545
gene id: 660470:THEBA_RS04545
uniprot id: I2F3V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

660470:THEBA RS01510
gene id: 660470:THEBA_RS01510
uniprot id: I2F253
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

660470:THEBA RS01915
gene id: 660470:THEBA_RS01915
uniprot id: I2F2D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

660470:THEBA RS10065
gene id: 660470:THEBA_RS10065
uniprot id: I2F6U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

660470:THEBA RS04830
gene id: 660470:THEBA_RS04830
uniprot id: I2F403
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

660470:THEBA RS10680
gene id: 660470:THEBA_RS10680
uniprot id: I2F770
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06830
gene id: 660470:THEBA_RS06830
uniprot id: I2F536
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

660470:THEBA RS02320
gene id: 660470:THEBA_RS02320
uniprot id: I2F2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS01625
gene id: 660470:THEBA_RS01625
uniprot id: I2F275
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

660470:THEBA RS04995
gene id: 660470:THEBA_RS04995
uniprot id: I2F434
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

660470:THEBA RS04400
gene id: 660470:THEBA_RS04400
uniprot id: E0HXR7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

660470:THEBA RS02715
gene id: 660470:THEBA_RS02715
uniprot id: I2F2T6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

660470:THEBA RS12905
gene id: 660470:THEBA_RS12905
uniprot id: I2F8D4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

660470:THEBA RS12470
gene id: 660470:THEBA_RS12470
uniprot id: I2F860
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

660470:THEBA RS01940
gene id: 660470:THEBA_RS01940
uniprot id: I2F2D5
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06800
gene id: 660470:THEBA_RS06800
uniprot id: I2F530
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

660470:THEBA RS06435
gene id: 660470:THEBA_RS06435
uniprot id: I2F4V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

660470:THEBA RS08185
gene id: 660470:THEBA_RS08185
uniprot id: I2F5T1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

660470:THEBA RS04100
gene id: 660470:THEBA_RS04100
uniprot id: I2F3K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

660470:THEBA RS13030
gene id: 660470:THEBA_RS13030
uniprot id: I2F8F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS06650
gene id: 660470:THEBA_RS06650
uniprot id: I2F501
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

660470:THEBA RS00675
gene id: 660470:THEBA_RS00675
uniprot id: I2F1Q8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

660470:THEBA RS01865
gene id: 660470:THEBA_RS01865
uniprot id: I2F2C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

660470:THEBA RS10480
gene id: 660470:THEBA_RS10480
uniprot id: I2F730
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

660470:THEBA RS03715
gene id: 660470:THEBA_RS03715
uniprot id: I2F3D4
names: Similarity
messages: Belongs to the MEMO1 family.

660470:THEBA RS12275
gene id: 660470:THEBA_RS12275
uniprot id: I2F824
names: Similarity
messages: Belongs to the ABC transporter superfamily.

660470:THEBA RS10850
gene id: 660470:THEBA_RS10850
uniprot id: I2F7A7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS07060
gene id: 660470:THEBA_RS07060
uniprot id: I2F581
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

660470:THEBA RS03395
gene id: 660470:THEBA_RS03395
uniprot id: I2F370
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

660470:THEBA RS12920
gene id: 660470:THEBA_RS12920
uniprot id: I2F8D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

660470:THEBA RS11130
gene id: 660470:THEBA_RS11130
uniprot id: I2F7G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS01925
gene id: 660470:THEBA_RS01925
uniprot id: I2F2D2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

660470:THEBA RS10705
gene id: 660470:THEBA_RS10705
uniprot id: I2F775
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

660470:THEBA RS07540
gene id: 660470:THEBA_RS07540
uniprot id: I2F5H0
names: Subcellular Location Annotation
messages: Cytoplasm

660470:THEBA RS01760
gene id: 660470:THEBA_RS01760
uniprot id: I2F299
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS01990
gene id: 660470:THEBA_RS01990
uniprot id: I2F2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

660470:THEBA RS06125
gene id: 660470:THEBA_RS06125
uniprot id: I2F4Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

660470:THEBA RS08290
gene id: 660470:THEBA_RS08290
uniprot id: I2F5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS04800
gene id: 660470:THEBA_RS04800
uniprot id: I2F3Z7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS12300
gene id: 660470:THEBA_RS12300
uniprot id: I2F829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

660470:THEBA RS08505
gene id: 660470:THEBA_RS08505
uniprot id: I2F659
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

660470:THEBA RS12325
gene id: 660470:THEBA_RS12325
uniprot id: I2F833
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07770
gene id: 660470:THEBA_RS07770
uniprot id: I2F5L1
names: Similarity
messages: Belongs to the acylphosphatase family.

660470:THEBA RS03535
gene id: 660470:THEBA_RS03535
uniprot id: I2F398
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

660470:THEBA RS04385
gene id: 660470:THEBA_RS04385
uniprot id: I2F3R7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

660470:THEBA RS03620
gene id: 660470:THEBA_RS03620
uniprot id: I2F3B5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

660470:THEBA RS12970
gene id: 660470:THEBA_RS12970
uniprot id: I2F8E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS09055
gene id: 660470:THEBA_RS09055
uniprot id: I2F6A0
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS02995
gene id: 660470:THEBA_RS02995
uniprot id: I2F2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

660470:THEBA RS06440
gene id: 660470:THEBA_RS06440
uniprot id: I2F4V9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS04080
gene id: 660470:THEBA_RS04080
uniprot id: I2F3K5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

660470:THEBA RS11395
gene id: 660470:THEBA_RS11395
uniprot id: I2F7L5
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06810
gene id: 660470:THEBA_RS06810
uniprot id: I2F532
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

660470:THEBA RS02920
gene id: 660470:THEBA_RS02920
uniprot id: I2F2X7
names: Similarity
messages: Belongs to the peptidase S1C family.

660470:THEBA RS10320
gene id: 660470:THEBA_RS10320
uniprot id: I2F701
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

660470:THEBA RS08890
gene id: 660470:THEBA_RS08890
uniprot id: I2F669
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS01930
gene id: 660470:THEBA_RS01930
uniprot id: I2F2D3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

660470:THEBA RS06390
gene id: 660470:THEBA_RS06390
uniprot id: I2F4U9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

660470:THEBA RS09390
gene id: 660470:THEBA_RS09390
uniprot id: I2F6G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

660470:THEBA RS04190
gene id: 660470:THEBA_RS04190
uniprot id: I2F3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS05385
gene id: 660470:THEBA_RS05385
uniprot id: I2F4A9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

660470:THEBA RS08620
gene id: 660470:THEBA_RS08620
uniprot id: I2F5U7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

660470:THEBA RS12080
gene id: 660470:THEBA_RS12080
uniprot id: I2F7Z1
names: Similarity
messages: Belongs to the FGGY kinase family.

660470:THEBA RS07530
gene id: 660470:THEBA_RS07530
uniprot id: I2F5G8
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04760
gene id: 660470:THEBA_RS04760
uniprot id: I2F3Y9
names: Similarity
messages: Belongs to the threonine synthase family.

660470:THEBA RS02895
gene id: 660470:THEBA_RS02895
uniprot id: I2F2X2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

660470:THEBA RS12130
gene id: 660470:THEBA_RS12130
uniprot id: I2F7Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS02955
gene id: 660470:THEBA_RS02955
uniprot id: I2F2Y4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS09365
gene id: 660470:THEBA_RS09365
uniprot id: I2F6G1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

660470:THEBA RS06285
gene id: 660470:THEBA_RS06285
uniprot id: I2F4S9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

660470:THEBA RS01465
gene id: 660470:THEBA_RS01465
uniprot id: I2F245
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

660470:THEBA RS09140
gene id: 660470:THEBA_RS09140
uniprot id: I2F6B7
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

660470:THEBA RS05740
gene id: 660470:THEBA_RS05740
uniprot id: I2F4H8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

660470:THEBA RS06990
gene id: 660470:THEBA_RS06990
uniprot id: I2F567
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

660470:THEBA RS04900
gene id: 660470:THEBA_RS04900
uniprot id: I2F415
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS04495
gene id: 660470:THEBA_RS04495
uniprot id: I2F3U0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS03590
gene id: 660470:THEBA_RS03590
uniprot id: I2F3A9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

660470:THEBA RS10425
gene id: 660470:THEBA_RS10425
uniprot id: I2F719
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08045
gene id: 660470:THEBA_RS08045
uniprot id: I2F5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS02700
gene id: 660470:THEBA_RS02700
uniprot id: I2F2T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

660470:THEBA RS00840
gene id: 660470:THEBA_RS00840
uniprot id: I2F1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS11655
gene id: 660470:THEBA_RS11655
uniprot id: I2F7R6
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06795
gene id: 660470:THEBA_RS06795
uniprot id: I2F529
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

660470:THEBA RS06600
gene id: 660470:THEBA_RS06600
uniprot id: I2F4Z1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

660470:THEBA RS01590
gene id: 660470:THEBA_RS01590
uniprot id: I2F269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

660470:THEBA RS07825
gene id: 660470:THEBA_RS07825
uniprot id: I2F5M0
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS03760
gene id: 660470:THEBA_RS03760
uniprot id: I2F3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

660470:THEBA RS01515
gene id: 660470:THEBA_RS01515
uniprot id: I2F254
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

660470:THEBA RS00670
gene id: 660470:THEBA_RS00670
uniprot id: I2F1Q7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS05815
gene id: 660470:THEBA_RS05815
uniprot id: I2F4J3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

660470:THEBA RS03210
gene id: 660470:THEBA_RS03210
uniprot id: I2F332
names: Similarity
messages: Belongs to the UPF0597 family.

660470:THEBA RS01985
gene id: 660470:THEBA_RS01985
uniprot id: I2F2E4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

660470:THEBA RS00950
gene id: 660470:THEBA_RS00950
uniprot id: I2F1V6
names: Similarity
messages: Belongs to the asparagine synthetase family.

660470:THEBA RS05045
gene id: 660470:THEBA_RS05045
uniprot id: I2F444
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

660470:THEBA RS02885
gene id: 660470:THEBA_RS02885
uniprot id: I2F2X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

660470:THEBA RS00835
gene id: 660470:THEBA_RS00835
uniprot id: I2F1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS02005
gene id: 660470:THEBA_RS02005
uniprot id: I2F2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

660470:THEBA RS03805
gene id: 660470:THEBA_RS03805
uniprot id: I2F3F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

660470:THEBA RS05190
gene id: 660470:THEBA_RS05190
uniprot id: I2F472
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

660470:THEBA RS02375
gene id: 660470:THEBA_RS02375
uniprot id: I2F2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS04550
gene id: 660470:THEBA_RS04550
uniprot id: I2F3V1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

660470:THEBA RS01655
gene id: 660470:THEBA_RS01655
uniprot id: I2F281
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

660470:THEBA RS06755
gene id: 660470:THEBA_RS06755
uniprot id: I2F521
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

660470:THEBA RS06140
gene id: 660470:THEBA_RS06140
uniprot id: I2F4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

660470:THEBA RS08915
gene id: 660470:THEBA_RS08915
uniprot id: I2F610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS12770
gene id: 660470:THEBA_RS12770
uniprot id: I2F8A7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS03635
gene id: 660470:THEBA_RS03635
uniprot id: I2F3B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

660470:THEBA RS05620
gene id: 660470:THEBA_RS05620
uniprot id: I2F4F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

660470:THEBA RS05640
gene id: 660470:THEBA_RS05640
uniprot id: I2F4F9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

660470:THEBA RS03790
gene id: 660470:THEBA_RS03790
uniprot id: I2F3E8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

660470:THEBA RS01805
gene id: 660470:THEBA_RS01805
uniprot id: I2F2A8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

660470:THEBA RS08230
gene id: 660470:THEBA_RS08230
uniprot id: I2F5U2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

660470:THEBA RS06475
gene id: 660470:THEBA_RS06475
uniprot id: I2F4W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

660470:THEBA RS05360
gene id: 660470:THEBA_RS05360
uniprot id: I2F4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

660470:THEBA RS09405
gene id: 660470:THEBA_RS09405
uniprot id: I2F6G9
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01230
gene id: 660470:THEBA_RS01230
uniprot id: I2F200
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

660470:THEBA RS03985
gene id: 660470:THEBA_RS03985
uniprot id: I2F3I6
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

660470:THEBA RS09155
gene id: 660470:THEBA_RS09155
uniprot id: I2F6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

660470:THEBA RS06235
gene id: 660470:THEBA_RS06235
uniprot id: I2F4R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

660470:THEBA RS04640
gene id: 660470:THEBA_RS04640
uniprot id: I2F3W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS10740
gene id: 660470:THEBA_RS10740
uniprot id: I2F779
names: Similarity
messages: Belongs to the threonine aldolase family.

660470:THEBA RS13550
gene id: 660470:THEBA_RS13550
uniprot id: I2F8Q6
names: Similarity
messages: Belongs to the UPF0111 family.

660470:THEBA RS10930
gene id: 660470:THEBA_RS10930
uniprot id: I2F7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

660470:THEBA RS06935
gene id: 660470:THEBA_RS06935
uniprot id: I2F556
names: Similarity
messages: Belongs to the class-I fumarase family.

660470:THEBA RS09100
gene id: 660470:THEBA_RS09100
uniprot id: E0HXU2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

660470:THEBA RS04115
gene id: 660470:THEBA_RS04115
uniprot id: I2F3L3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

660470:THEBA RS09025
gene id: 660470:THEBA_RS09025
uniprot id: I2F694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS12125
gene id: 660470:THEBA_RS12125
uniprot id: I2F7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS01875
gene id: 660470:THEBA_RS01875
uniprot id: I2F2C2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS02840
gene id: 660470:THEBA_RS02840
uniprot id: I2F2W1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

660470:THEBA RS04765
gene id: 660470:THEBA_RS04765
uniprot id: I2F3Z0
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

660470:THEBA RS06910
gene id: 660470:THEBA_RS06910
uniprot id: I2F551
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

660470:THEBA RS12865
gene id: 660470:THEBA_RS12865
uniprot id: I2F8C6
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

660470:THEBA RS13365
gene id: 660470:THEBA_RS13365
uniprot id: I2F8M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

660470:THEBA RS02835
gene id: 660470:THEBA_RS02835
uniprot id: I2F2W0
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08965
gene id: 660470:THEBA_RS08965
uniprot id: I2F682
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

660470:THEBA RS06450
gene id: 660470:THEBA_RS06450
uniprot id: I2F4W1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

660470:THEBA RS11465
gene id: 660470:THEBA_RS11465
uniprot id: I2F7M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

660470:THEBA RS00310
gene id: 660470:THEBA_RS00310
uniprot id: I2F1J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

660470:THEBA RS10445
gene id: 660470:THEBA_RS10445
uniprot id: I2F723
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01635
gene id: 660470:THEBA_RS01635
uniprot id: I2F277
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

660470:THEBA RS11925
gene id: 660470:THEBA_RS11925
uniprot id: I2F7W1
names: Similarity
messages: Belongs to the GSP E family.

660470:THEBA RS11955
gene id: 660470:THEBA_RS11955
uniprot id: I2F7W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS11200
gene id: 660470:THEBA_RS11200
uniprot id: I2F7H5
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

660470:THEBA RS02465
gene id: 660470:THEBA_RS02465
uniprot id: I2F2N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

660470:THEBA RS10975
gene id: 660470:THEBA_RS10975
uniprot id: I2F7D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

660470:THEBA RS01900
gene id: 660470:THEBA_RS01900
uniprot id: I2F2C7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS02480
gene id: 660470:THEBA_RS02480
uniprot id: I2F2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

660470:THEBA RS09120
gene id: 660470:THEBA_RS09120
uniprot id: I2F6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

660470:THEBA RS12975
gene id: 660470:THEBA_RS12975
uniprot id: I2F8E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS07205
gene id: 660470:THEBA_RS07205
uniprot id: I2F5A7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04110
gene id: 660470:THEBA_RS04110
uniprot id: I2F3L2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

660470:THEBA RS04840
gene id: 660470:THEBA_RS04840
uniprot id: I2F405
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

660470:THEBA RS02335
gene id: 660470:THEBA_RS02335
uniprot id: I2F2L3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

660470:THEBA RS02020
gene id: 660470:THEBA_RS02020
uniprot id: I2F2F0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

660470:THEBA RS04135
gene id: 660470:THEBA_RS04135
uniprot id: I2F3L7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

660470:THEBA RS06430
gene id: 660470:THEBA_RS06430
uniprot id: I2F4V7
names: Similarity
messages: Belongs to the CinA family.

660470:THEBA RS07490
gene id: 660470:THEBA_RS07490
uniprot id: I2F5G1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

660470:THEBA RS08330
gene id: 660470:THEBA_RS08330
uniprot id: I2F5W5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

660470:THEBA RS13505
gene id: 660470:THEBA_RS13505
uniprot id: I2F8P8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

660470:THEBA RS07550
gene id: 660470:THEBA_RS07550
uniprot id: I2F5H2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

660470:THEBA RS13300
gene id: 660470:THEBA_RS13300
uniprot id: I2F8K7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01130
gene id: 660470:THEBA_RS01130
uniprot id: I2F1Y4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

660470:THEBA RS07230
gene id: 660470:THEBA_RS07230
uniprot id: I2F5B1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

660470:THEBA RS13495
gene id: 660470:THEBA_RS13495
uniprot id: I2F8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS00240
gene id: 660470:THEBA_RS00240
uniprot id: I2F1H7
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

660470:THEBA RS10090
gene id: 660470:THEBA_RS10090
uniprot id: I2F6V0
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01630
gene id: 660470:THEBA_RS01630
uniprot id: I2F276
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

660470:THEBA RS00175
gene id: 660470:THEBA_RS00175
uniprot id: I2F1G5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

660470:THEBA RS06375
gene id: 660470:THEBA_RS06375
uniprot id: I2F4U6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

660470:THEBA RS04160
gene id: 660470:THEBA_RS04160
uniprot id: I2F3M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

660470:THEBA RS02255
gene id: 660470:THEBA_RS02255
uniprot id: I2F2J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

660470:THEBA RS02505
gene id: 660470:THEBA_RS02505
uniprot id: I2F2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS08425
gene id: 660470:THEBA_RS08425
uniprot id: I2F5Y1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS01910
gene id: 660470:THEBA_RS01910
uniprot id: I2F2C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

660470:THEBA RS03505
gene id: 660470:THEBA_RS03505
uniprot id: I2F392
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

660470:THEBA RS10960
gene id: 660470:THEBA_RS10960
uniprot id: I2F7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

660470:THEBA RS11630
gene id: 660470:THEBA_RS11630
uniprot id: I2F7R1
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

660470:THEBA RS13580
gene id: 660470:THEBA_RS13580
uniprot id: I2F8R2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

660470:THEBA RS08610
gene id: 660470:THEBA_RS08610
uniprot id: E0HXR7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

660470:THEBA RS04500
gene id: 660470:THEBA_RS04500
uniprot id: I2F3U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

660470:THEBA RS01205
gene id: 660470:THEBA_RS01205
uniprot id: I2F1Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

660470:THEBA RS01350
gene id: 660470:THEBA_RS01350
uniprot id: I2F224
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

660470:THEBA RS11615
gene id: 660470:THEBA_RS11615
uniprot id: I2F7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

660470:THEBA RS03735
gene id: 660470:THEBA_RS03735
uniprot id: I2F3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

660470:THEBA RS03455
gene id: 660470:THEBA_RS03455
uniprot id: I2F382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

660470:THEBA RS03495
gene id: 660470:THEBA_RS03495
uniprot id: I2F390
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

660470:THEBA RS03935
gene id: 660470:THEBA_RS03935
uniprot id: I2F3H6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

660470:THEBA RS01860
gene id: 660470:THEBA_RS01860
uniprot id: I2F2B9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

660470:THEBA RS06940
gene id: 660470:THEBA_RS06940
uniprot id: I2F557
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

660470:THEBA RS07860
gene id: 660470:THEBA_RS07860
uniprot id: I2F5M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

660470:THEBA RS04635
gene id: 660470:THEBA_RS04635
uniprot id: I2F3W7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

660470:THEBA RS11415
gene id: 660470:THEBA_RS11415
uniprot id: I2F7L9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

660470:THEBA RS04055
gene id: 660470:THEBA_RS04055
uniprot id: I2F3K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

660470:THEBA RS06770
gene id: 660470:THEBA_RS06770
uniprot id: I2F524
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

660470:THEBA RS12805
gene id: 660470:THEBA_RS12805
uniprot id: I2F8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS02145
gene id: 660470:THEBA_RS02145
uniprot id: I2F2H6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

660470:THEBA RS02580
gene id: 660470:THEBA_RS02580
uniprot id: I2F2R2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04945
gene id: 660470:THEBA_RS04945
uniprot id: I2F424
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS13075
gene id: 660470:THEBA_RS13075
uniprot id: I2F8G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS02445
gene id: 660470:THEBA_RS02445
uniprot id: I2F2N5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

660470:THEBA RS09355
gene id: 660470:THEBA_RS09355
uniprot id: I2F6F9
names: Similarity
messages: Belongs to the peptidase C56 family.

660470:THEBA RS04940
gene id: 660470:THEBA_RS04940
uniprot id: I2F423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS03315
gene id: 660470:THEBA_RS03315
uniprot id: I2F355
names: Similarity
messages: Belongs to the HAM1 NTPase family.

660470:THEBA RS12485
gene id: 660470:THEBA_RS12485
uniprot id: I2F863
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

660470:THEBA RS06385
gene id: 660470:THEBA_RS06385
uniprot id: I2F4U8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

660470:THEBA RS07250
gene id: 660470:THEBA_RS07250
uniprot id: I2F5B5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

660470:THEBA RS03575
gene id: 660470:THEBA_RS03575
uniprot id: I2F3A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

660470:THEBA RS05110
gene id: 660470:THEBA_RS05110
uniprot id: I2F456
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

660470:THEBA RS02755
gene id: 660470:THEBA_RS02755
uniprot id: I2F2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

660470:THEBA RS08175
gene id: 660470:THEBA_RS08175
uniprot id: I2F5S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

660470:THEBA RS12430
gene id: 660470:THEBA_RS12430
uniprot id: I2F853
names: Similarity
messages: Belongs to the peptidase S9C family.

660470:THEBA RS06525
gene id: 660470:THEBA_RS06525
uniprot id: I2F4X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

660470:THEBA RS11110
gene id: 660470:THEBA_RS11110
uniprot id: I2F7F7
names: Similarity
messages: Belongs to the FGGY kinase family.

660470:THEBA RS05935
gene id: 660470:THEBA_RS05935
uniprot id: I2F4L4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS06255
gene id: 660470:THEBA_RS06255
uniprot id: I2F4S3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

660470:THEBA RS00145
gene id: 660470:THEBA_RS00145
uniprot id: I2F1F9
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

660470:THEBA RS05170
gene id: 660470:THEBA_RS05170
uniprot id: I2F468
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS11740
gene id: 660470:THEBA_RS11740
uniprot id: I2F7S9
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS03450
gene id: 660470:THEBA_RS03450
uniprot id: I2F381
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

660470:THEBA RS10175
gene id: 660470:THEBA_RS10175
uniprot id: I2F6X2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

660470:THEBA RS03055
gene id: 660470:THEBA_RS03055
uniprot id: I2F301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

660470:THEBA RS08270
gene id: 660470:THEBA_RS08270
uniprot id: I2F624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS10950
gene id: 660470:THEBA_RS10950
uniprot id: I2F7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

660470:THEBA RS04105
gene id: 660470:THEBA_RS04105
uniprot id: I2F3L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

660470:THEBA RS04270
gene id: 660470:THEBA_RS04270
uniprot id: I2F3P3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08535
gene id: 660470:THEBA_RS08535
uniprot id: I2F602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS10325
gene id: 660470:THEBA_RS10325
uniprot id: I2F702
names: Similarity
messages: Belongs to the ClpA/ClpB family.

660470:THEBA RS04170
gene id: 660470:THEBA_RS04170
uniprot id: I2F3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

660470:THEBA RS06960
gene id: 660470:THEBA_RS06960
uniprot id: I2F561
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

660470:THEBA RS11365
gene id: 660470:THEBA_RS11365
uniprot id: I2F7K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS05660
gene id: 660470:THEBA_RS05660
uniprot id: E0HXR7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

660470:THEBA RS12910
gene id: 660470:THEBA_RS12910
uniprot id: I2F8D5
names: Similarity
messages: Belongs to the FGGY kinase family.

660470:THEBA RS04215
gene id: 660470:THEBA_RS04215
uniprot id: I2F3N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

660470:THEBA RS06950
gene id: 660470:THEBA_RS06950
uniprot id: I2F559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

660470:THEBA RS00210
gene id: 660470:THEBA_RS00210
uniprot id: I2F1H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

660470:THEBA RS03310
gene id: 660470:THEBA_RS03310
uniprot id: I2F354
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS03030
gene id: 660470:THEBA_RS03030
uniprot id: I2F2Z6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

660470:THEBA RS13410
gene id: 660470:THEBA_RS13410
uniprot id: I2F8M9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

660470:THEBA RS01165
gene id: 660470:THEBA_RS01165
uniprot id: I2F1Z1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

660470:THEBA RS09040
gene id: 660470:THEBA_RS09040
uniprot id: I2F697
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

660470:THEBA RS03645
gene id: 660470:THEBA_RS03645
uniprot id: I2F3C0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

660470:THEBA RS13055
gene id: 660470:THEBA_RS13055
uniprot id: I2F8G2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS10690
gene id: 660470:THEBA_RS10690
uniprot id: I2F772
names: Similarity
messages: Belongs to the peptidase U62 family.

660470:THEBA RS05610
gene id: 660470:THEBA_RS05610
uniprot id: I2F4F3
names: Subunit
messages: Homodimer.

660470:THEBA RS06155
gene id: 660470:THEBA_RS06155
uniprot id: I2F4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

660470:THEBA RS01425
gene id: 660470:THEBA_RS01425
uniprot id: I2F239
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

660470:THEBA RS02235
gene id: 660470:THEBA_RS02235
uniprot id: I2F2J4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

660470:THEBA RS02675
gene id: 660470:THEBA_RS02675
uniprot id: I2F2T1
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS10830
gene id: 660470:THEBA_RS10830
uniprot id: I2F7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

660470:THEBA RS06410
gene id: 660470:THEBA_RS06410
uniprot id: I2F4V3
names: Similarity
messages: Belongs to the peptidase M18 family.

660470:THEBA RS12010
gene id: 660470:THEBA_RS12010
uniprot id: I2F7X6
names: Similarity
messages: Belongs to the acylphosphatase family.

660470:THEBA RS00985
gene id: 660470:THEBA_RS00985
uniprot id: I2F1W3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS10010
gene id: 660470:THEBA_RS10010
uniprot id: I2F6T4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

660470:THEBA RS04675
gene id: 660470:THEBA_RS04675
uniprot id: I2F3X3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

660470:THEBA RS08265
gene id: 660470:THEBA_RS08265
uniprot id: I2F5V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS00845
gene id: 660470:THEBA_RS00845
uniprot id: I2F1U0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

660470:THEBA RS04250
gene id: 660470:THEBA_RS04250
uniprot id: I2F3N9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

660470:THEBA RS10095
gene id: 660470:THEBA_RS10095
uniprot id: I2F6V1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

660470:THEBA RS10450
gene id: 660470:THEBA_RS10450
uniprot id: I2F724
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06825
gene id: 660470:THEBA_RS06825
uniprot id: I2F535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

660470:THEBA RS00265
gene id: 660470:THEBA_RS00265
uniprot id: I2F1I2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

660470:THEBA RS04060
gene id: 660470:THEBA_RS04060
uniprot id: I2F3K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

660470:THEBA RS11015
gene id: 660470:THEBA_RS11015
uniprot id: I2F7D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

660470:THEBA RS03165
gene id: 660470:THEBA_RS03165
uniprot id: I2F324
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

660470:THEBA RS11045
gene id: 660470:THEBA_RS11045
uniprot id: I2F7E5
names: Similarity
messages: Belongs to the pyruvate kinase family.

660470:THEBA RS06925
gene id: 660470:THEBA_RS06925
uniprot id: I2F554
names: Similarity
messages: Belongs to the glutathione peroxidase family.

660470:THEBA RS10150
gene id: 660470:THEBA_RS10150
uniprot id: I2F6W2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

660470:THEBA RS03650
gene id: 660470:THEBA_RS03650
uniprot id: I2F3C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

660470:THEBA RS12930
gene id: 660470:THEBA_RS12930
uniprot id: I2F8D9
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

660470:THEBA RS06790
gene id: 660470:THEBA_RS06790
uniprot id: I2F528
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

660470:THEBA RS09190
gene id: 660470:THEBA_RS09190
uniprot id: I2F6C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

660470:THEBA RS00255
gene id: 660470:THEBA_RS00255
uniprot id: I2F1I0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

660470:THEBA RS09445
gene id: 660470:THEBA_RS09445
uniprot id: I2F6H8
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01585
gene id: 660470:THEBA_RS01585
uniprot id: I2F268
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

660470:THEBA RS13315
gene id: 660470:THEBA_RS13315
uniprot id: I2F8L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

660470:THEBA RS08015
gene id: 660470:THEBA_RS08015
uniprot id: I2F5Q3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

660470:THEBA RS01570
gene id: 660470:THEBA_RS01570
uniprot id: I2F265
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

660470:THEBA RS08835
gene id: 660470:THEBA_RS08835
uniprot id: I2F660
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

660470:THEBA RS09815
gene id: 660470:THEBA_RS09815
uniprot id: I2F6P6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

660470:THEBA RS03930
gene id: 660470:THEBA_RS03930
uniprot id: I2F3H5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

660470:THEBA RS02870
gene id: 660470:THEBA_RS02870
uniprot id: I2F2W7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

660470:THEBA RS03425
gene id: 660470:THEBA_RS03425
uniprot id: I2F376
names: Similarity
messages: Belongs to the phosphohexose mutase family.

660470:THEBA RS00470
gene id: 660470:THEBA_RS00470
uniprot id: I2F1L9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

660470:THEBA RS08415
gene id: 660470:THEBA_RS08415
uniprot id: I2F5Y0
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS08465
gene id: 660470:THEBA_RS08465
uniprot id: I2F5Y9
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06250
gene id: 660470:THEBA_RS06250
uniprot id: I2F4S2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

660470:THEBA RS03110
gene id: 660470:THEBA_RS03110
uniprot id: I2F312
names: Similarity
messages: Belongs to the peptidase C69 family.

660470:THEBA RS03600
gene id: 660470:THEBA_RS03600
uniprot id: I2F3B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

660470:THEBA RS01565
gene id: 660470:THEBA_RS01565
uniprot id: I2F264
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

660470:THEBA RS01170
gene id: 660470:THEBA_RS01170
uniprot id: I2F1Z2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

660470:THEBA RS05355
gene id: 660470:THEBA_RS05355
uniprot id: I2F4A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

660470:THEBA RS03570
gene id: 660470:THEBA_RS03570
uniprot id: I2F3A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

660470:THEBA RS13120
gene id: 660470:THEBA_RS13120
uniprot id: I2F8H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

660470:THEBA RS04570
gene id: 660470:THEBA_RS04570
uniprot id: I2F3V5
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS06775
gene id: 660470:THEBA_RS06775
uniprot id: I2F525
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

660470:THEBA RS07855
gene id: 660470:THEBA_RS07855
uniprot id: I2F5M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

660470:THEBA RS00515
gene id: 660470:THEBA_RS00515
uniprot id: I2F1M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07470
gene id: 660470:THEBA_RS07470
uniprot id: I2F5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

660470:THEBA RS02640
gene id: 660470:THEBA_RS02640
uniprot id: I2F2S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS06405
gene id: 660470:THEBA_RS06405
uniprot id: I2F4V2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

660470:THEBA RS04590
gene id: 660470:THEBA_RS04590
uniprot id: I2F3V9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

660470:THEBA RS09475
gene id: 660470:THEBA_RS09475
uniprot id: I2F6I2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

660470:THEBA RS06835
gene id: 660470:THEBA_RS06835
uniprot id: I2F537
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS03480
gene id: 660470:THEBA_RS03480
uniprot id: I2F387
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

660470:THEBA RS12810
gene id: 660470:THEBA_RS12810
uniprot id: I2F8B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS04860
gene id: 660470:THEBA_RS04860
uniprot id: I2F409
names: Similarity
messages: Belongs to the band 7/mec-2 family.

660470:THEBA RS04265
gene id: 660470:THEBA_RS04265
uniprot id: I2F3P2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08090
gene id: 660470:THEBA_RS08090
uniprot id: I2F5R4
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS04045
gene id: 660470:THEBA_RS04045
uniprot id: I2F3J8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

660470:THEBA RS01560
gene id: 660470:THEBA_RS01560
uniprot id: I2F263
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

660470:THEBA RS10500
gene id: 660470:THEBA_RS10500
uniprot id: I2F734
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS13195
gene id: 660470:THEBA_RS13195
uniprot id: I2F8I8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

660470:THEBA RS00910
gene id: 660470:THEBA_RS00910
uniprot id: I2F1V0
names: Similarity
messages: Belongs to the asparagine synthetase family.

660470:THEBA RS12370
gene id: 660470:THEBA_RS12370
uniprot id: I2F842
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

660470:THEBA RS09485
gene id: 660470:THEBA_RS09485
uniprot id: I2F6I4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

660470:THEBA RS07255
gene id: 660470:THEBA_RS07255
uniprot id: I2F5B6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

660470:THEBA RS10085
gene id: 660470:THEBA_RS10085
uniprot id: I2F6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

660470:THEBA RS04445
gene id: 660470:THEBA_RS04445
uniprot id: I2F3T0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

660470:THEBA RS02315
gene id: 660470:THEBA_RS02315
uniprot id: I2F2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS05115
gene id: 660470:THEBA_RS05115
uniprot id: I2F457
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

660470:THEBA RS05490
gene id: 660470:THEBA_RS05490
uniprot id: I2F4D0
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

660470:THEBA RS06505
gene id: 660470:THEBA_RS06505
uniprot id: I2F4X2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS03630
gene id: 660470:THEBA_RS03630
uniprot id: I2F3B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

660470:THEBA RS13630
gene id: 660470:THEBA_RS13630
uniprot id: I2F8R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS03750
gene id: 660470:THEBA_RS03750
uniprot id: I2F3E1
names: Similarity
messages: Belongs to the YicC/YloC family.

660470:THEBA RS03025
gene id: 660470:THEBA_RS03025
uniprot id: I2F2Z5
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

660470:THEBA RS03595
gene id: 660470:THEBA_RS03595
uniprot id: I2F3B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

660470:THEBA RS01185
gene id: 660470:THEBA_RS01185
uniprot id: I2F1Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS02825
gene id: 660470:THEBA_RS02825
uniprot id: I2F2V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS07430
gene id: 660470:THEBA_RS07430
uniprot id: I2F5F0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

660470:THEBA RS09370
gene id: 660470:THEBA_RS09370
uniprot id: I2F6G2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

660470:THEBA RS03730
gene id: 660470:THEBA_RS03730
uniprot id: I2F3D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

660470:THEBA RS04780
gene id: 660470:THEBA_RS04780
uniprot id: I2F3Z3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

660470:THEBA RS08665
gene id: 660470:THEBA_RS08665
uniprot id: I2F627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS01955
gene id: 660470:THEBA_RS01955
uniprot id: I2F2D8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

660470:THEBA RS05775
gene id: 660470:THEBA_RS05775
uniprot id: E0HXR7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

660470:THEBA RS03350
gene id: 660470:THEBA_RS03350
uniprot id: I2F361
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

660470:THEBA RS10745
gene id: 660470:THEBA_RS10745
uniprot id: I2F781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

660470:THEBA RS03880
gene id: 660470:THEBA_RS03880
uniprot id: I2F3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS01660
gene id: 660470:THEBA_RS01660
uniprot id: I2F282
names: Similarity
messages: Belongs to the RecJ family.

660470:THEBA RS12025
gene id: 660470:THEBA_RS12025
uniprot id: I2F7X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS06785
gene id: 660470:THEBA_RS06785
uniprot id: I2F527
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

660470:THEBA RS04480
gene id: 660470:THEBA_RS04480
uniprot id: I2F3T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

660470:THEBA RS13025
gene id: 660470:THEBA_RS13025
uniprot id: I2F8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS03500
gene id: 660470:THEBA_RS03500
uniprot id: I2F391
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

660470:THEBA RS04520
gene id: 660470:THEBA_RS04520
uniprot id: I2F3U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

660470:THEBA RS03190
gene id: 660470:THEBA_RS03190
uniprot id: I2F329
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS02460
gene id: 660470:THEBA_RS02460
uniprot id: I2F2N8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

660470:THEBA RS09565
gene id: 660470:THEBA_RS09565
uniprot id: I2F6K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS05430
gene id: 660470:THEBA_RS05430
uniprot id: I2F4B8
names: Similarity
messages: Belongs to the peptidase C40 family.

660470:THEBA RS00605
gene id: 660470:THEBA_RS00605
uniprot id: I2F1P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane

660470:THEBA RS12895
gene id: 660470:THEBA_RS12895
uniprot id: I2F8D2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS02830
gene id: 660470:THEBA_RS02830
uniprot id: I2F2V9
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS12375
gene id: 660470:THEBA_RS12375
uniprot id: I2F843
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

660470:THEBA RS05350
gene id: 660470:THEBA_RS05350
uniprot id: I2F4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

660470:THEBA RS05485
gene id: 660470:THEBA_RS05485
uniprot id: I2F4C9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

660470:THEBA RS01315
gene id: 660470:THEBA_RS01315
uniprot id: I2F217
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

660470:THEBA RS10225
gene id: 660470:THEBA_RS10225
uniprot id: I2F6Y4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

660470:THEBA RS03115
gene id: 660470:THEBA_RS03115
uniprot id: I2F313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

660470:THEBA RS01190
gene id: 660470:THEBA_RS01190
uniprot id: I2F1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS06380
gene id: 660470:THEBA_RS06380
uniprot id: I2F4U7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

660470:THEBA RS12940
gene id: 660470:THEBA_RS12940
uniprot id: I2F8E1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

660470:THEBA RS03925
gene id: 660470:THEBA_RS03925
uniprot id: I2F3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

660470:THEBA RS00945
gene id: 660470:THEBA_RS00945
uniprot id: I2F1V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

660470:THEBA RS11115
gene id: 660470:THEBA_RS11115
uniprot id: I2F7F8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

660470:THEBA RS02250
gene id: 660470:THEBA_RS02250
uniprot id: I2F2J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

660470:THEBA RS05155
gene id: 660470:THEBA_RS05155
uniprot id: I2F465
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS02420
gene id: 660470:THEBA_RS02420
uniprot id: I2F2N0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

660470:THEBA RS08670
gene id: 660470:THEBA_RS08670
uniprot id: I2F5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07335
gene id: 660470:THEBA_RS07335
uniprot id: I2F5D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

660470:THEBA RS10410
gene id: 660470:THEBA_RS10410
uniprot id: I2F716
names: Similarity
messages: Belongs to the peptidase S8 family.

660470:THEBA RS12480
gene id: 660470:THEBA_RS12480
uniprot id: I2F862
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

660470:THEBA RS07570
gene id: 660470:THEBA_RS07570
uniprot id: I2F5H6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

660470:THEBA RS04880
gene id: 660470:THEBA_RS04880
uniprot id: I2F413
names: Similarity
messages: Belongs to the peptidase S66 family.

660470:THEBA RS10310
gene id: 660470:THEBA_RS10310
uniprot id: I2F6Z9
names: Cofactor
messages: Binds 2 irons ions per subunit via 4 cysteine residues per iron.

660470:THEBA RS11540
gene id: 660470:THEBA_RS11540
uniprot id: E0HXR7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

660470:THEBA RS02635
gene id: 660470:THEBA_RS02635
uniprot id: I2F2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07690
gene id: 660470:THEBA_RS07690
uniprot id: I2F5J5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

660470:THEBA RS03320
gene id: 660470:THEBA_RS03320
uniprot id: I2F356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

660470:THEBA RS07935
gene id: 660470:THEBA_RS07935
uniprot id: I2F5P0
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS00505
gene id: 660470:THEBA_RS00505
uniprot id: I2F1M6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

660470:THEBA RS05210
gene id: 660470:THEBA_RS05210
uniprot id: I2F476
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04555
gene id: 660470:THEBA_RS04555
uniprot id: I2F3V2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

660470:THEBA RS03525
gene id: 660470:THEBA_RS03525
uniprot id: I2F396
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

660470:THEBA RS06715
gene id: 660470:THEBA_RS06715
uniprot id: I2F513
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

660470:THEBA RS11190
gene id: 660470:THEBA_RS11190
uniprot id: I2F7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07600
gene id: 660470:THEBA_RS07600
uniprot id: I2F5I2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

660470:THEBA RS12345
gene id: 660470:THEBA_RS12345
uniprot id: I2F837
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS09500
gene id: 660470:THEBA_RS09500
uniprot id: I2F6I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

660470:THEBA RS09325
gene id: 660470:THEBA_RS09325
uniprot id: I2F6F3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS02100
gene id: 660470:THEBA_RS02100
uniprot id: I2F2G6
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS05365
gene id: 660470:THEBA_RS05365
uniprot id: I2F4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

660470:THEBA RS13390
gene id: 660470:THEBA_RS13390
uniprot id: I2F8M5
names: Similarity
messages: Belongs to the UxaA family.

660470:THEBA RS05185
gene id: 660470:THEBA_RS05185
uniprot id: I2F471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

660470:THEBA RS13280
gene id: 660470:THEBA_RS13280
uniprot id: I2F8K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS07475
gene id: 660470:THEBA_RS07475
uniprot id: I2F5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS06075
gene id: 660470:THEBA_RS06075
uniprot id: I2F4P3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

660470:THEBA RS09730
gene id: 660470:THEBA_RS09730
uniprot id: I2F6M9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

660470:THEBA RS05945
gene id: 660470:THEBA_RS05945
uniprot id: I2F4L6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

660470:THEBA RS12060
gene id: 660470:THEBA_RS12060
uniprot id: I2F7Y7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01135
gene id: 660470:THEBA_RS01135
uniprot id: I2F1Y5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

660470:THEBA RS05670
gene id: 660470:THEBA_RS05670
uniprot id: I2F4G4
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01970
gene id: 660470:THEBA_RS01970
uniprot id: I2F2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

660470:THEBA RS03680
gene id: 660470:THEBA_RS03680
uniprot id: I2F3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

660470:THEBA RS01555
gene id: 660470:THEBA_RS01555
uniprot id: I2F262
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

660470:THEBA RS09955
gene id: 660470:THEBA_RS09955
uniprot id: I2F6S3
names: Similarity
messages: Belongs to the peptidase C1 family.

660470:THEBA RS11475
gene id: 660470:THEBA_RS11475
uniprot id: I2F7N1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

660470:THEBA RS07055
gene id: 660470:THEBA_RS07055
uniprot id: I2F580
names: Similarity
messages: Belongs to the FGGY kinase family.

660470:THEBA RS08240
gene id: 660470:THEBA_RS08240
uniprot id: I2F5U7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

660470:THEBA RS07400
gene id: 660470:THEBA_RS07400
uniprot id: I2F5E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

660470:THEBA RS06510
gene id: 660470:THEBA_RS06510
uniprot id: I2F4X3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04235
gene id: 660470:THEBA_RS04235
uniprot id: I2F3N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

660470:THEBA RS01945
gene id: 660470:THEBA_RS01945
uniprot id: I2F2D6
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS10025
gene id: 660470:THEBA_RS10025
uniprot id: I2F6T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS05530
gene id: 660470:THEBA_RS05530
uniprot id: I2F4D8
names: Similarity
messages: Belongs to the peptidase M20A family.

660470:THEBA RS02050
gene id: 660470:THEBA_RS02050
uniprot id: I2F2F6
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

660470:THEBA RS12720
gene id: 660470:THEBA_RS12720
uniprot id: I2F899
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS03405
gene id: 660470:THEBA_RS03405
uniprot id: I2F372
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

660470:THEBA RS10165
gene id: 660470:THEBA_RS10165
uniprot id: I2F6X0
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

660470:THEBA RS12330
gene id: 660470:THEBA_RS12330
uniprot id: I2F834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS01755
gene id: 660470:THEBA_RS01755
uniprot id: I2F298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS11330
gene id: 660470:THEBA_RS11330
uniprot id: I2F7K1
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

660470:THEBA RS07750
gene id: 660470:THEBA_RS07750
uniprot id: I2F5K7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

660470:THEBA RS10595
gene id: 660470:THEBA_RS10595
uniprot id: I2F753
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

660470:THEBA RS01995
gene id: 660470:THEBA_RS01995
uniprot id: I2F2E6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

660470:THEBA RS11000
gene id: 660470:THEBA_RS11000
uniprot id: I2F7D7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS10890
gene id: 660470:THEBA_RS10890
uniprot id: I2F7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS01120
gene id: 660470:THEBA_RS01120
uniprot id: I2F1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

660470:THEBA RS11920
gene id: 660470:THEBA_RS11920
uniprot id: I2F7W0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

660470:THEBA RS09030
gene id: 660470:THEBA_RS09030
uniprot id: I2F695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS12745
gene id: 660470:THEBA_RS12745
uniprot id: I2F8A2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS13330
gene id: 660470:THEBA_RS13330
uniprot id: I2F8L3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS05030
gene id: 660470:THEBA_RS05030
uniprot id: I2F441
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08040
gene id: 660470:THEBA_RS08040
uniprot id: I2F5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS13190
gene id: 660470:THEBA_RS13190
uniprot id: I2F8I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS07185
gene id: 660470:THEBA_RS07185
uniprot id: I2F5A3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

660470:THEBA RS03515
gene id: 660470:THEBA_RS03515
uniprot id: I2F394
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

660470:THEBA RS13125
gene id: 660470:THEBA_RS13125
uniprot id: I2F8H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

660470:THEBA RS06420
gene id: 660470:THEBA_RS06420
uniprot id: I2F4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07050
gene id: 660470:THEBA_RS07050
uniprot id: I2F579
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

660470:THEBA RS04390
gene id: 660470:THEBA_RS04390
uniprot id: I2F3R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

660470:THEBA RS04980
gene id: 660470:THEBA_RS04980
uniprot id: I2F431
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS10205
gene id: 660470:THEBA_RS10205
uniprot id: I2F6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS05320
gene id: 660470:THEBA_RS05320
uniprot id: I2F496
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

660470:THEBA RS09555
gene id: 660470:THEBA_RS09555
uniprot id: I2F6J8
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

660470:THEBA RS09980
gene id: 660470:THEBA_RS09980
uniprot id: I2F6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS03010
gene id: 660470:THEBA_RS03010
uniprot id: I2F2Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

660470:THEBA RS08790
gene id: 660470:THEBA_RS08790
uniprot id: I2F5Y9
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS11460
gene id: 660470:THEBA_RS11460
uniprot id: I2F7M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

660470:THEBA RS01480
gene id: 660470:THEBA_RS01480
uniprot id: I2F248
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

660470:THEBA RS04835
gene id: 660470:THEBA_RS04835
uniprot id: I2F404
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS02710
gene id: 660470:THEBA_RS02710
uniprot id: I2F2T5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

660470:THEBA RS00155
gene id: 660470:THEBA_RS00155
uniprot id: I2F1G1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

660470:THEBA RS07375
gene id: 660470:THEBA_RS07375
uniprot id: I2F5E0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

660470:THEBA RS04240
gene id: 660470:THEBA_RS04240
uniprot id: I2F3N7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

660470:THEBA RS07090
gene id: 660470:THEBA_RS07090
uniprot id: I2F587
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS00355
gene id: 660470:THEBA_RS00355
uniprot id: I2F1J7
names: Similarity
messages: Belongs to the peptidase U62 family.

660470:THEBA RS06355
gene id: 660470:THEBA_RS06355
uniprot id: I2F4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

660470:THEBA RS13450
gene id: 660470:THEBA_RS13450
uniprot id: I2F8N7
names: Similarity
messages: Belongs to the leucine-binding protein family.

660470:THEBA RS01535
gene id: 660470:THEBA_RS01535
uniprot id: I2F258
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

660470:THEBA RS01720
gene id: 660470:THEBA_RS01720
uniprot id: I2F293
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

660470:THEBA RS11410
gene id: 660470:THEBA_RS11410
uniprot id: I2F7L8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

660470:THEBA RS08590
gene id: 660470:THEBA_RS08590
uniprot id: I2F610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07455
gene id: 660470:THEBA_RS07455
uniprot id: I2F5F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

660470:THEBA RS09905
gene id: 660470:THEBA_RS09905
uniprot id: I2F6R2
names: Similarity
messages: Belongs to the peptidase C69 family.

660470:THEBA RS13500
gene id: 660470:THEBA_RS13500
uniprot id: I2F8P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS12385
gene id: 660470:THEBA_RS12385
uniprot id: I2F845
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

660470:THEBA RS09655
gene id: 660470:THEBA_RS09655
uniprot id: I2F6L7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS12535
gene id: 660470:THEBA_RS12535
uniprot id: I2F871
names: Similarity
messages: Belongs to the FGGY kinase family.

660470:THEBA RS00320
gene id: 660470:THEBA_RS00320
uniprot id: I2F1J2
names: Similarity
messages: Belongs to the peptidase U62 family.

660470:THEBA RS02000
gene id: 660470:THEBA_RS02000
uniprot id: I2F2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

660470:THEBA RS03545
gene id: 660470:THEBA_RS03545
uniprot id: I2F3A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

660470:THEBA RS12030
gene id: 660470:THEBA_RS12030
uniprot id: I2F7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS05625
gene id: 660470:THEBA_RS05625
uniprot id: I2F4F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

660470:THEBA RS13385
gene id: 660470:THEBA_RS13385
uniprot id: I2F8M4
names: Similarity
messages: Belongs to the peptidase M20A family.

660470:THEBA RS03420
gene id: 660470:THEBA_RS03420
uniprot id: I2F375
names: Similarity
messages: Belongs to the UPF0102 family.

660470:THEBA RS09535
gene id: 660470:THEBA_RS09535
uniprot id: I2F6J4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

660470:THEBA RS08720
gene id: 660470:THEBA_RS08720
uniprot id: I2F638
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01415
gene id: 660470:THEBA_RS01415
uniprot id: I2F237
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS07785
gene id: 660470:THEBA_RS07785
uniprot id: I2F5L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

660470:THEBA RS00200
gene id: 660470:THEBA_RS00200
uniprot id: I2F1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

660470:THEBA RS02280
gene id: 660470:THEBA_RS02280
uniprot id: I2F2K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

660470:THEBA RS08285
gene id: 660470:THEBA_RS08285
uniprot id: I2F627
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS01395
gene id: 660470:THEBA_RS01395
uniprot id: I2F233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

660470:THEBA RS00580
gene id: 660470:THEBA_RS00580
uniprot id: I2F1N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

660470:THEBA RS07200
gene id: 660470:THEBA_RS07200
uniprot id: I2F5A6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

660470:THEBA RS07085
gene id: 660470:THEBA_RS07085
uniprot id: I2F586
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS03755
gene id: 660470:THEBA_RS03755
uniprot id: I2F3E2
names: Similarity
messages: Belongs to the RemA family.

660470:THEBA RS06260
gene id: 660470:THEBA_RS06260
uniprot id: I2F4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

660470:THEBA RS03510
gene id: 660470:THEBA_RS03510
uniprot id: I2F393
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

660470:THEBA RS11495
gene id: 660470:THEBA_RS11495
uniprot id: I2F7N5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

660470:THEBA RS00475
gene id: 660470:THEBA_RS00475
uniprot id: I2F1M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

660470:THEBA RS03795
gene id: 660470:THEBA_RS03795
uniprot id: I2F3E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

660470:THEBA RS09240
gene id: 660470:THEBA_RS09240
uniprot id: I2F6D7
names: Similarity
messages: Belongs to the pyruvate kinase family.

660470:THEBA RS10250
gene id: 660470:THEBA_RS10250
uniprot id: I2F6Y9
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

660470:THEBA RS10330
gene id: 660470:THEBA_RS10330
uniprot id: I2F703
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

660470:THEBA RS07295
gene id: 660470:THEBA_RS07295
uniprot id: I2F5C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

660470:THEBA RS12475
gene id: 660470:THEBA_RS12475
uniprot id: I2F861
names: Similarity
messages: Belongs to the peptidase S45 family.

660470:THEBA RS09900
gene id: 660470:THEBA_RS09900
uniprot id: I2F6R1
names: Similarity
messages: Belongs to the peptidase C69 family.

660470:THEBA RS03580
gene id: 660470:THEBA_RS03580
uniprot id: I2F3A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

660470:THEBA RS03550
gene id: 660470:THEBA_RS03550
uniprot id: I2F3A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

660470:THEBA RS02265
gene id: 660470:THEBA_RS02265
uniprot id: I2F2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

660470:THEBA RS13235
gene id: 660470:THEBA_RS13235
uniprot id: I2F8J5
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS07495
gene id: 660470:THEBA_RS07495
uniprot id: I2F5G2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

660470:THEBA RS09045
gene id: 660470:THEBA_RS09045
uniprot id: I2F698
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

660470:THEBA RS11610
gene id: 660470:THEBA_RS11610
uniprot id: I2F7Q7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS00315
gene id: 660470:THEBA_RS00315
uniprot id: I2F1J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS01935
gene id: 660470:THEBA_RS01935
uniprot id: I2F2D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

660470:THEBA RS12120
gene id: 660470:THEBA_RS12120
uniprot id: I2F7Z7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

660470:THEBA RS02355
gene id: 660470:THEBA_RS02355
uniprot id: I2F2L8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

660470:THEBA RS11030
gene id: 660470:THEBA_RS11030
uniprot id: I2F7E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

660470:THEBA RS09520
gene id: 660470:THEBA_RS09520
uniprot id: I2F6J1
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

660470:THEBA RS11185
gene id: 660470:THEBA_RS11185
uniprot id: I2F7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS03340
gene id: 660470:THEBA_RS03340
uniprot id: I2F359
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

660470:THEBA RS00165
gene id: 660470:THEBA_RS00165
uniprot id: I2F1G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

660470:THEBA RS11020
gene id: 660470:THEBA_RS11020
uniprot id: I2F7E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

660470:THEBA RS01615
gene id: 660470:THEBA_RS01615
uniprot id: I2F273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS09290
gene id: 660470:THEBA_RS09290
uniprot id: I2F6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS07790
gene id: 660470:THEBA_RS07790
uniprot id: I2F5L5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

660470:THEBA RS02820
gene id: 660470:THEBA_RS02820
uniprot id: I2F2V7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

660470:THEBA RS02985
gene id: 660470:THEBA_RS02985
uniprot id: I2F2Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

660470:THEBA RS09920
gene id: 660470:THEBA_RS09920
uniprot id: I2F6R5
names: Similarity
messages: Belongs to the peptidase C69 family.

660470:THEBA RS07100
gene id: 660470:THEBA_RS07100
uniprot id: I2F589
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

660470:THEBA RS03475
gene id: 660470:THEBA_RS03475
uniprot id: I2F386
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

660470:THEBA RS03135
gene id: 660470:THEBA_RS03135
uniprot id: I2F318
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

660470:THEBA RS02810
gene id: 660470:THEBA_RS02810
uniprot id: I2F2V5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

660470:THEBA RS12705
gene id: 660470:THEBA_RS12705
uniprot id: I2F897
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

660470:THEBA RS03800
gene id: 660470:THEBA_RS03800
uniprot id: I2F3F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

660470:THEBA RS01690
gene id: 660470:THEBA_RS01690
uniprot id: I2F287
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

660470:THEBA RS09375
gene id: 660470:THEBA_RS09375
uniprot id: I2F6G3
names: Similarity
messages: Belongs to the Skp family.

660470:THEBA RS10605
gene id: 660470:THEBA_RS10605
uniprot id: I2F755
names: Similarity
messages: Belongs to the peptidase S8 family.

660470:THEBA RS04095
gene id: 660470:THEBA_RS04095
uniprot id: I2F3K8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

660470:THEBA RS01340
gene id: 660470:THEBA_RS01340
uniprot id: I2F222
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS08160
gene id: 660470:THEBA_RS08160
uniprot id: I2F5S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

660470:THEBA RS03785
gene id: 660470:THEBA_RS03785
uniprot id: I2F3E7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

660470:THEBA RS00305
gene id: 660470:THEBA_RS00305
uniprot id: I2F1I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

660470:THEBA RS00205
gene id: 660470:THEBA_RS00205
uniprot id: I2F1H1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

660470:THEBA RS06710
gene id: 660470:THEBA_RS06710
uniprot id: I2F512
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

660470:THEBA RS06240
gene id: 660470:THEBA_RS06240
uniprot id: I2F4S0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

660470:THEBA RS12765
gene id: 660470:THEBA_RS12765
uniprot id: I2F8A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

660470:THEBA RS00935
gene id: 660470:THEBA_RS00935
uniprot id: I2F1V3
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

660470:THEBA RS04845
gene id: 660470:THEBA_RS04845
uniprot id: I2F406
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

660470:THEBA RS11915
gene id: 660470:THEBA_RS11915
uniprot id: I2F7V9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

660470:THEBA RS11980
gene id: 660470:THEBA_RS11980
uniprot id: I2F7X1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

660470:THEBA RS08815
gene id: 660470:THEBA_RS08815
uniprot id: E0HXR7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

660470:THEBA RS10590
gene id: 660470:THEBA_RS10590
uniprot id: I2F752
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

660470:THEBA RS02370
gene id: 660470:THEBA_RS02370
uniprot id: I2F2M1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

660470:THEBA RS00995
gene id: 660470:THEBA_RS00995
uniprot id: I2F1W5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

660470:THEBA RS07245
gene id: 660470:THEBA_RS07245
uniprot id: I2F5B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS01140
gene id: 660470:THEBA_RS01140
uniprot id: I2F1Y6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS02545
gene id: 660470:THEBA_RS02545
uniprot id: I2F2Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

660470:THEBA RS00900
gene id: 660470:THEBA_RS00900
uniprot id: I2F1U8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

660470:THEBA RS05345
gene id: 660470:THEBA_RS05345
uniprot id: I2F4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

660470:THEBA RS13445
gene id: 660470:THEBA_RS13445
uniprot id: I2F8N6
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS13260
gene id: 660470:THEBA_RS13260
uniprot id: I2F8K1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

660470:THEBA RS12680
gene id: 660470:THEBA_RS12680
uniprot id: I2F892
names: Similarity
messages: Belongs to the FGGY kinase family.

660470:THEBA RS13070
gene id: 660470:THEBA_RS13070
uniprot id: I2F8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS12255
gene id: 660470:THEBA_RS12255
uniprot id: I2F820
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

660470:THEBA RS04905
gene id: 660470:THEBA_RS04905
uniprot id: I2F416
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

660470:THEBA RS05440
gene id: 660470:THEBA_RS05440
uniprot id: I2F4C0
names: Similarity
messages: Belongs to the UPF0473 family.

660470:THEBA RS03665
gene id: 660470:THEBA_RS03665
uniprot id: I2F3C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

660470:THEBA RS01895
gene id: 660470:THEBA_RS01895
uniprot id: I2F2C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

660470:THEBA RS03610
gene id: 660470:THEBA_RS03610
uniprot id: I2F3B3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

660470:THEBA RS08710
gene id: 660470:THEBA_RS08710
uniprot id: I2F5W5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

660470:THEBA RS07955
gene id: 660470:THEBA_RS07955
uniprot id: I2F5P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

660470:THEBA RS05570
gene id: 660470:THEBA_RS05570
uniprot id: I2F4E5
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01375
gene id: 660470:THEBA_RS01375
uniprot id: I2F229
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

660470:THEBA RS11990
gene id: 660470:THEBA_RS11990
uniprot id: I2F7X3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS09735
gene id: 660470:THEBA_RS09735
uniprot id: I2F6N0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

660470:THEBA RS03160
gene id: 660470:THEBA_RS03160
uniprot id: I2F323
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

660470:THEBA RS09000
gene id: 660470:THEBA_RS09000
uniprot id: I2F689
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

660470:THEBA RS04990
gene id: 660470:THEBA_RS04990
uniprot id: I2F433
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

660470:THEBA RS04140
gene id: 660470:THEBA_RS04140
uniprot id: I2F3L8
names: Similarity
messages: Belongs to the IMPACT family.

660470:THEBA RS08490
gene id: 660470:THEBA_RS08490
uniprot id: E0HXR7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

660470:THEBA RS01145
gene id: 660470:THEBA_RS01145
uniprot id: I2F1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

660470:THEBA RS04815
gene id: 660470:THEBA_RS04815
uniprot id: I2F400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS06005
gene id: 660470:THEBA_RS06005
uniprot id: I2F4M8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

660470:THEBA RS02890
gene id: 660470:THEBA_RS02890
uniprot id: I2F2X1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS05535
gene id: 660470:THEBA_RS05535
uniprot id: I2F4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS03875
gene id: 660470:THEBA_RS03875
uniprot id: I2F3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS09050
gene id: 660470:THEBA_RS09050
uniprot id: I2F699
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04020
gene id: 660470:THEBA_RS04020
uniprot id: I2F3J3
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

660470:THEBA RS00745
gene id: 660470:THEBA_RS00745
uniprot id: I2F1S2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

660470:THEBA RS02260
gene id: 660470:THEBA_RS02260
uniprot id: I2F2J9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

660470:THEBA RS09605
gene id: 660470:THEBA_RS09605
uniprot id: I2F6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

660470:THEBA RS02590
gene id: 660470:THEBA_RS02590
uniprot id: I2F2R5
names: Similarity
messages: Belongs to the peptidase C69 family.

660470:THEBA RS01115
gene id: 660470:THEBA_RS01115
uniprot id: I2F1Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

660470:THEBA RS02115
gene id: 660470:THEBA_RS02115
uniprot id: I2F2G9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

660470:THEBA RS06295
gene id: 660470:THEBA_RS06295
uniprot id: I2F4T1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

660470:THEBA RS00980
gene id: 660470:THEBA_RS00980
uniprot id: I2F1W2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS09745
gene id: 660470:THEBA_RS09745
uniprot id: I2F6N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS01450
gene id: 660470:THEBA_RS01450
uniprot id: I2F242
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

660470:THEBA RS01160
gene id: 660470:THEBA_RS01160
uniprot id: I2F1Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

660470:THEBA RS09965
gene id: 660470:THEBA_RS09965
uniprot id: I2F6S5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS05130
gene id: 660470:THEBA_RS05130
uniprot id: I2F460
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

660470:THEBA RS00220
gene id: 660470:THEBA_RS00220
uniprot id: I2F1H4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

660470:THEBA RS04490
gene id: 660470:THEBA_RS04490
uniprot id: I2F3T9
names: Similarity
messages: Belongs to the asp23 family.

660470:THEBA RS07315
gene id: 660470:THEBA_RS07315
uniprot id: I2F5C8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

660470:THEBA RS06030
gene id: 660470:THEBA_RS06030
uniprot id: I2F4N2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

660470:THEBA RS05635
gene id: 660470:THEBA_RS05635
uniprot id: I2F4F8
names: Similarity
messages: Belongs to the aspartokinase family.

660470:THEBA RS11935
gene id: 660470:THEBA_RS11935
uniprot id: I2F7W3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS03540
gene id: 660470:THEBA_RS03540
uniprot id: I2F399
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

660470:THEBA RS03555
gene id: 660470:THEBA_RS03555
uniprot id: I2F3A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

660470:THEBA RS10610
gene id: 660470:THEBA_RS10610
uniprot id: I2F756
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

660470:THEBA RS01475
gene id: 660470:THEBA_RS01475
uniprot id: I2F247
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

660470:THEBA RS05565
gene id: 660470:THEBA_RS05565
uniprot id: I2F4E4
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08860
gene id: 660470:THEBA_RS08860
uniprot id: I2F602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS05540
gene id: 660470:THEBA_RS05540
uniprot id: I2F4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS07615
gene id: 660470:THEBA_RS07615
uniprot id: I2F5I6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS10825
gene id: 660470:THEBA_RS10825
uniprot id: I2F7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

660470:THEBA RS03765
gene id: 660470:THEBA_RS03765
uniprot id: I2F3E4
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

660470:THEBA RS06150
gene id: 660470:THEBA_RS06150
uniprot id: I2F4Q8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

660470:THEBA RS08320
gene id: 660470:THEBA_RS08320
uniprot id: I2F5W3
names: Similarity
messages: Belongs to the BtpA family.

660470:THEBA RS04360
gene id: 660470:THEBA_RS04360
uniprot id: I2F3R3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04575
gene id: 660470:THEBA_RS04575
uniprot id: I2F3V6
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01855
gene id: 660470:THEBA_RS01855
uniprot id: I2F2B8
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS05165
gene id: 660470:THEBA_RS05165
uniprot id: I2F467
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS10335
gene id: 660470:THEBA_RS10335
uniprot id: I2F704
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

660470:THEBA RS00585
gene id: 660470:THEBA_RS00585
uniprot id: I2F1N9
names: Similarity
messages: Belongs to the peptidase S9C family.

660470:THEBA RS05995
gene id: 660470:THEBA_RS05995
uniprot id: I2F4M6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

660470:THEBA RS11750
gene id: 660470:THEBA_RS11750
uniprot id: I2F7T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

660470:THEBA RS11780
gene id: 660470:THEBA_RS11780
uniprot id: I2F7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS09780
gene id: 660470:THEBA_RS09780
uniprot id: I2F6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS03300
gene id: 660470:THEBA_RS03300
uniprot id: I2F352
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

660470:THEBA RS09060
gene id: 660470:THEBA_RS09060
uniprot id: I2F6A1
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS07725
gene id: 660470:THEBA_RS07725
uniprot id: I2F5K2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

660470:THEBA RS07360
gene id: 660470:THEBA_RS07360
uniprot id: I2F5D7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08920
gene id: 660470:THEBA_RS08920
uniprot id: I2F674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS05305
gene id: 660470:THEBA_RS05305
uniprot id: I2F493
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IspH family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Cytoplasm

660470:THEBA RS09345
gene id: 660470:THEBA_RS09345
uniprot id: I2F6F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

660470:THEBA RS03830
gene id: 660470:THEBA_RS03830
uniprot id: I2F3F6
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS13610
gene id: 660470:THEBA_RS13610
uniprot id: I2F8R6
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS04165
gene id: 660470:THEBA_RS04165
uniprot id: I2F3M3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS10105
gene id: 660470:THEBA_RS10105
uniprot id: I2F6V3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

660470:THEBA RS02495
gene id: 660470:THEBA_RS02495
uniprot id: I2F2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS09690
gene id: 660470:THEBA_RS09690
uniprot id: I2F6M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS06955
gene id: 660470:THEBA_RS06955
uniprot id: I2F560
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

660470:THEBA RS00790
gene id: 660470:THEBA_RS00790
uniprot id: I2F1T2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

660470:THEBA RS01150
gene id: 660470:THEBA_RS01150
uniprot id: I2F1Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

660470:THEBA RS01605
gene id: 660470:THEBA_RS01605
uniprot id: I2F271
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

660470:THEBA RS03325
gene id: 660470:THEBA_RS03325
uniprot id: I2F357
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

660470:THEBA RS04855
gene id: 660470:THEBA_RS04855
uniprot id: I2F408
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS02275
gene id: 660470:THEBA_RS02275
uniprot id: I2F2K2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

660470:THEBA RS02060
gene id: 660470:THEBA_RS02060
uniprot id: I2F2F8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

660470:THEBA RS07925
gene id: 660470:THEBA_RS07925
uniprot id: I2F5N8
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

660470:THEBA RS08945
gene id: 660470:THEBA_RS08945
uniprot id: I2F679
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS09065
gene id: 660470:THEBA_RS09065
uniprot id: I2F6A2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS07535
gene id: 660470:THEBA_RS07535
uniprot id: I2F5G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS01825
gene id: 660470:THEBA_RS01825
uniprot id: I2F2B2
names: Similarity
messages: Belongs to the UPF0047 family.

660470:THEBA RS01045
gene id: 660470:THEBA_RS01045
uniprot id: I2F1X4
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04125
gene id: 660470:THEBA_RS04125
uniprot id: I2F3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

660470:THEBA RS02470
gene id: 660470:THEBA_RS02470
uniprot id: I2F2P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

660470:THEBA RS02270
gene id: 660470:THEBA_RS02270
uniprot id: I2F2K1
names: Similarity
messages: Belongs to the DprA/Smf family.

660470:THEBA RS02240
gene id: 660470:THEBA_RS02240
uniprot id: I2F2J5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

660470:THEBA RS06930
gene id: 660470:THEBA_RS06930
uniprot id: I2F555
names: Similarity
messages: Belongs to the class-I fumarase family.

660470:THEBA RS05925
gene id: 660470:THEBA_RS05925
uniprot id: I2F4L2
names: Similarity
messages: Belongs to the peptidase S8 family.

660470:THEBA RS02595
gene id: 660470:THEBA_RS02595
uniprot id: I2F2R6
names: Similarity
messages: Belongs to the peptidase C69 family.

660470:THEBA RS02805
gene id: 660470:THEBA_RS02805
uniprot id: I2F2V4
names: Similarity
messages: Belongs to the histone deacetylase family.

660470:THEBA RS05010
gene id: 660470:THEBA_RS05010
uniprot id: I2F437
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

660470:THEBA RS09990
gene id: 660470:THEBA_RS09990
uniprot id: I2F6T0
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS04810
gene id: 660470:THEBA_RS04810
uniprot id: I2F3Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS13440
gene id: 660470:THEBA_RS13440
uniprot id: I2F8N5
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS05290
gene id: 660470:THEBA_RS05290
uniprot id: I2F490
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

660470:THEBA RS07280
gene id: 660470:THEBA_RS07280
uniprot id: I2F5C1
names: Similarity
messages: Belongs to the AB hydrolase superfamily.

660470:THEBA RS02770
gene id: 660470:THEBA_RS02770
uniprot id: I2F2U7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

660470:THEBA RS07510
gene id: 660470:THEBA_RS07510
uniprot id: I2F5G4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS00365
gene id: 660470:THEBA_RS00365
uniprot id: I2F1J8
names: Similarity
messages: Belongs to the glutamine synthetase family.

660470:THEBA RS11985
gene id: 660470:THEBA_RS11985
uniprot id: I2F7X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

660470:THEBA RS04335
gene id: 660470:THEBA_RS04335
uniprot id: I2F3Q6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

660470:THEBA RS04470
gene id: 660470:THEBA_RS04470
uniprot id: I2F3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

660470:THEBA RS11025
gene id: 660470:THEBA_RS11025
uniprot id: I2F7E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

660470:THEBA RS13005
gene id: 660470:THEBA_RS13005
uniprot id: I2F8F3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

660470:THEBA RS10055
gene id: 660470:THEBA_RS10055
uniprot id: I2F6U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

660470:THEBA RS06645
gene id: 660470:THEBA_RS06645
uniprot id: I2F500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

660470:THEBA RS04035
gene id: 660470:THEBA_RS04035
uniprot id: I2F3J6
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

660470:THEBA RS10660
gene id: 660470:THEBA_RS10660
uniprot id: I2F766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS03965
gene id: 660470:THEBA_RS03965
uniprot id: I2F3I2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

660470:THEBA RS04195
gene id: 660470:THEBA_RS04195
uniprot id: I2F3M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS02975
gene id: 660470:THEBA_RS02975
uniprot id: I2F2Y5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

660470:THEBA RS13090
gene id: 660470:THEBA_RS13090
uniprot id: I2F8G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

660470:THEBA RS02440
gene id: 660470:THEBA_RS02440
uniprot id: I2F2N4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

660470:THEBA RS05005
gene id: 660470:THEBA_RS05005
uniprot id: I2F436
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

660470:THEBA RS09135
gene id: 660470:THEBA_RS09135
uniprot id: I2F6B6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

660470:THEBA RS06860
gene id: 660470:THEBA_RS06860
uniprot id: I2F542
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08645
gene id: 660470:THEBA_RS08645
uniprot id: I2F5V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS01920
gene id: 660470:THEBA_RS01920
uniprot id: I2F2D1
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS11050
gene id: 660470:THEBA_RS11050
uniprot id: I2F7E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

660470:THEBA RS10985
gene id: 660470:THEBA_RS10985
uniprot id: I2F7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

660470:THEBA RS04465
gene id: 660470:THEBA_RS04465
uniprot id: I2F3T4
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS11210
gene id: 660470:THEBA_RS11210
uniprot id: I2F7H7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

660470:THEBA RS02130
gene id: 660470:THEBA_RS02130
uniprot id: I2F2H3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

660470:THEBA RS05630
gene id: 660470:THEBA_RS05630
uniprot id: I2F4F7
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

660470:THEBA RS08180
gene id: 660470:THEBA_RS08180
uniprot id: I2F5T0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

660470:THEBA RS03815
gene id: 660470:THEBA_RS03815
uniprot id: I2F3F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

660470:THEBA RS06820
gene id: 660470:THEBA_RS06820
uniprot id: I2F534
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS02705
gene id: 660470:THEBA_RS02705
uniprot id: I2F2T4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

660470:THEBA RS13325
gene id: 660470:THEBA_RS13325
uniprot id: I2F8L2
names: Similarity
messages: Belongs to the UPF0047 family.

660470:THEBA RS01435
gene id: 660470:THEBA_RS01435
uniprot id: I2F241
names: Similarity
messages: Belongs to the PspA/IM30 family.

660470:THEBA RS04130
gene id: 660470:THEBA_RS04130
uniprot id: I2F3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

660470:THEBA RS02555
gene id: 660470:THEBA_RS02555
uniprot id: I2F2Q7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

660470:THEBA RS06735
gene id: 660470:THEBA_RS06735
uniprot id: I2F517
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

660470:THEBA RS05665
gene id: 660470:THEBA_RS05665
uniprot id: I2F4G3
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS11820
gene id: 660470:THEBA_RS11820
uniprot id: I2F7U2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

660470:THEBA RS01550
gene id: 660470:THEBA_RS01550
uniprot id: I2F261
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

660470:THEBA RS09675
gene id: 660470:THEBA_RS09675
uniprot id: I2F6L9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

660470:THEBA RS03945
gene id: 660470:THEBA_RS03945
uniprot id: I2F3H8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

660470:THEBA RS13470
gene id: 660470:THEBA_RS13470
uniprot id: I2F8P1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

660470:THEBA RS11120
gene id: 660470:THEBA_RS11120
uniprot id: I2F7F9
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

660470:THEBA RS04510
gene id: 660470:THEBA_RS04510
uniprot id: I2F3U3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

660470:THEBA RS04985
gene id: 660470:THEBA_RS04985
uniprot id: I2F432
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

660470:THEBA RS03740
gene id: 660470:THEBA_RS03740
uniprot id: I2F3D9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

660470:THEBA RS10540
gene id: 660470:THEBA_RS10540
uniprot id: I2F742
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

660470:THEBA RS09480
gene id: 660470:THEBA_RS09480
uniprot id: I2F6I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

660470:THEBA RS00940
gene id: 660470:THEBA_RS00940
uniprot id: I2F1V4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

660470:THEBA RS05285
gene id: 660470:THEBA_RS05285
uniprot id: I2F489
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

660470:THEBA RS09175
gene id: 660470:THEBA_RS09175
uniprot id: I2F6C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

660470:THEBA RS07520
gene id: 660470:THEBA_RS07520
uniprot id: I2F5G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

660470:THEBA RS02815
gene id: 660470:THEBA_RS02815
uniprot id: I2F2V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

660470:THEBA RS05835
gene id: 660470:THEBA_RS05835
uniprot id: I2F4J6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

660470:THEBA RS07105
gene id: 660470:THEBA_RS07105
uniprot id: I2F590
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

660470:THEBA RS08595
gene id: 660470:THEBA_RS08595
uniprot id: I2F674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS11380
gene id: 660470:THEBA_RS11380
uniprot id: I2F7L2
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS11055
gene id: 660470:THEBA_RS11055
uniprot id: I2F7E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

660470:THEBA RS08340
gene id: 660470:THEBA_RS08340
uniprot id: I2F638
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS01410
gene id: 660470:THEBA_RS01410
uniprot id: I2F236
names: Similarity
messages: Belongs to the carbamate kinase family.

660470:THEBA RS10585
gene id: 660470:THEBA_RS10585
uniprot id: I2F751
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

660470:THEBA RS11735
gene id: 660470:THEBA_RS11735
uniprot id: I2F7S8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

660470:THEBA RS03225
gene id: 660470:THEBA_RS03225
uniprot id: I2F335
names: Similarity
messages: Belongs to the CapA family.

660470:THEBA RS00905
gene id: 660470:THEBA_RS00905
uniprot id: I2F1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

660470:THEBA RS11880
gene id: 660470:THEBA_RS11880
uniprot id: I2F7V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS08550
gene id: 660470:THEBA_RS08550
uniprot id: I2F667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

660470:THEBA RS05195
gene id: 660470:THEBA_RS05195
uniprot id: I2F473
names: Similarity
messages: Belongs to the peptidase S33 family.

660470:THEBA RS00120
gene id: 660470:THEBA_RS00120
uniprot id: I2F1F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

660470:THEBA RS13555
gene id: 660470:THEBA_RS13555
uniprot id: I2F8Q7
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS03530
gene id: 660470:THEBA_RS03530
uniprot id: I2F397
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

660470:THEBA RS05375
gene id: 660470:THEBA_RS05375
uniprot id: I2F4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

660470:THEBA RS03140
gene id: 660470:THEBA_RS03140
uniprot id: I2F319
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

660470:THEBA RS03410
gene id: 660470:THEBA_RS03410
uniprot id: I2F373
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

660470:THEBA RS03780
gene id: 660470:THEBA_RS03780
uniprot id: I2F3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

660470:THEBA RS00520
gene id: 660470:THEBA_RS00520
uniprot id: I2F1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS06915
gene id: 660470:THEBA_RS06915
uniprot id: I2F552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS03215
gene id: 660470:THEBA_RS03215
uniprot id: I2F333
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

660470:THEBA RS00895
gene id: 660470:THEBA_RS00895
uniprot id: I2F1U7
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

660470:THEBA RS00860
gene id: 660470:THEBA_RS00860
uniprot id: I2F1U3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

660470:THEBA RS11230
gene id: 660470:THEBA_RS11230
uniprot id: I2F7I1
names: Subcellular Location Annotation
messages: Membrane

660470:THEBA RS08650
gene id: 660470:THEBA_RS08650
uniprot id: I2F624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS00180
gene id: 660470:THEBA_RS00180
uniprot id: I2F1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Monomer.

660470:THEBA RS07565
gene id: 660470:THEBA_RS07565
uniprot id: I2F5H5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

660470:THEBA RS08875
gene id: 660470:THEBA_RS08875
uniprot id: I2F667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

660470:THEBA RS11785
gene id: 660470:THEBA_RS11785
uniprot id: I2F7T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

660470:THEBA RS04715
gene id: 660470:THEBA_RS04715
uniprot id: I2F3Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

660470:THEBA RS10940
gene id: 660470:THEBA_RS10940
uniprot id: I2F7C6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

660470:THEBA RS11125
gene id: 660470:THEBA_RS11125
uniprot id: I2F7G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

660470:THEBA RS05015
gene id: 660470:THEBA_RS05015
uniprot id: I2F438
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

660470:THEBA RS11360
gene id: 660470:THEBA_RS11360
uniprot id: I2F7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS03810
gene id: 660470:THEBA_RS03810
uniprot id: I2F3F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

660470:THEBA RS10765
gene id: 660470:THEBA_RS10765
uniprot id: I2F785
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

660470:THEBA RS02925
gene id: 660470:THEBA_RS02925
uniprot id: I2F2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

660470:THEBA RS03605
gene id: 660470:THEBA_RS03605
uniprot id: I2F3B2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

660470:THEBA RS06415
gene id: 660470:THEBA_RS06415
uniprot id: I2F4V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

660470:THEBA RS03365
gene id: 660470:THEBA_RS03365
uniprot id: I2F364
names: Similarity
messages: Belongs to the ComB family.

660470:THEBA RS01675
gene id: 660470:THEBA_RS01675
uniprot id: I2F284
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

660470:THEBA RS04515
gene id: 660470:THEBA_RS04515
uniprot id: I2F3U4
names: Similarity
messages: Belongs to the asp23 family.

660470:THEBA RS03920
gene id: 660470:THEBA_RS03920
uniprot id: I2F3H3
names: Similarity
messages: Belongs to the FGGY kinase family.

660470:THEBA RS04340
gene id: 660470:THEBA_RS04340
uniprot id: I2F3Q7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

660470:THEBA RS07515
gene id: 660470:THEBA_RS07515
uniprot id: I2F5G5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

660470:THEBA RS08370
gene id: 660470:THEBA_RS08370
uniprot id: I2F5X2
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

660470:THEBA RS07025
gene id: 660470:THEBA_RS07025
uniprot id: I2F574
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

660470:THEBA RS03625
gene id: 660470:THEBA_RS03625
uniprot id: I2F3B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

660470:THEBA RS03835
gene id: 660470:THEBA_RS03835
uniprot id: I2F3F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

660470:THEBA RS12605
gene id: 660470:THEBA_RS12605
uniprot id: I2F882
names: Subunit
messages: Homodimer.

660470:THEBA RS05615
gene id: 660470:THEBA_RS05615
uniprot id: I2F4F4
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.