648996:THEAM RS06410
gene id: 648996:THEAM_RS06410
uniprot id: E8T3A5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

648996:THEAM RS05200
gene id: 648996:THEAM_RS05200
uniprot id: E8T2A7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS00020
gene id: 648996:THEAM_RS00020
uniprot id: E8T2Q3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS02955
gene id: 648996:THEAM_RS02955
uniprot id: E8T5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

648996:THEAM RS02050
gene id: 648996:THEAM_RS02050
uniprot id: E8T4V9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

648996:THEAM RS04465
gene id: 648996:THEAM_RS04465
uniprot id: E8T1V7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS05635
gene id: 648996:THEAM_RS05635
uniprot id: E8T2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

648996:THEAM RS00805
gene id: 648996:THEAM_RS00805
uniprot id: E8T3J9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

648996:THEAM RS03060
gene id: 648996:THEAM_RS03060
uniprot id: E8T5Z0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

648996:THEAM RS03320
gene id: 648996:THEAM_RS03320
uniprot id: E8T640
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

648996:THEAM RS07845
gene id: 648996:THEAM_RS07845
uniprot id: E8T4Y1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

648996:THEAM RS03380
gene id: 648996:THEAM_RS03380
uniprot id: E8T651
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

648996:THEAM RS03475
gene id: 648996:THEAM_RS03475
uniprot id: E8T670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

648996:THEAM RS08380
gene id: 648996:THEAM_RS08380
uniprot id: E8T5F0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

648996:THEAM RS07945
gene id: 648996:THEAM_RS07945
uniprot id: E8T4Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

648996:THEAM RS03465
gene id: 648996:THEAM_RS03465
uniprot id: E8T668
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

648996:THEAM RS05500
gene id: 648996:THEAM_RS05500
uniprot id: E8T2G7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

648996:THEAM RS02635
gene id: 648996:THEAM_RS02635
uniprot id: E8T5L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

648996:THEAM RS01530
gene id: 648996:THEAM_RS01530
uniprot id: E8T4D7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

648996:THEAM RS03715
gene id: 648996:THEAM_RS03715
uniprot id: E8T6B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS07110
gene id: 648996:THEAM_RS07110
uniprot id: E8T442
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

648996:THEAM RS01160
gene id: 648996:THEAM_RS01160
uniprot id: E8T3Y9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

648996:THEAM RS04165
gene id: 648996:THEAM_RS04165
uniprot id: E8T6K8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

648996:THEAM RS08550
gene id: 648996:THEAM_RS08550
uniprot id: E8T5I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS08640
gene id: 648996:THEAM_RS08640
uniprot id: E8T5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

648996:THEAM RS02875
gene id: 648996:THEAM_RS02875
uniprot id: E8T5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

648996:THEAM RS04985
gene id: 648996:THEAM_RS04985
uniprot id: E8T263
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

648996:THEAM RS06590
gene id: 648996:THEAM_RS06590
uniprot id: E8T3E0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

648996:THEAM RS03180
gene id: 648996:THEAM_RS03180
uniprot id: E8T614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

648996:THEAM RS08120
gene id: 648996:THEAM_RS08120
uniprot id: E8T531
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

648996:THEAM RS08225
gene id: 648996:THEAM_RS08225
uniprot id: E8T5D0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

648996:THEAM RS03890
gene id: 648996:THEAM_RS03890
uniprot id: E8T6F0
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS08625
gene id: 648996:THEAM_RS08625
uniprot id: E8T5S3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

648996:THEAM RS01935
gene id: 648996:THEAM_RS01935
uniprot id: E8T4T7
names: Similarity
messages: Belongs to the AOR/FOR family.

648996:THEAM RS00885
gene id: 648996:THEAM_RS00885
uniprot id: E8T3L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

648996:THEAM RS00445
gene id: 648996:THEAM_RS00445
uniprot id: E8T357
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

648996:THEAM RS06345
gene id: 648996:THEAM_RS06345
uniprot id: E8T393
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS00815
gene id: 648996:THEAM_RS00815
uniprot id: E8T3K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

648996:THEAM RS05155
gene id: 648996:THEAM_RS05155
uniprot id: E8T298
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

648996:THEAM RS03610
gene id: 648996:THEAM_RS03610
uniprot id: E8T697
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

648996:THEAM RS06580
gene id: 648996:THEAM_RS06580
uniprot id: E8T3D8
names: Similarity
messages: Belongs to the UPF0045 family.

648996:THEAM RS09370
gene id: 648996:THEAM_RS09370
uniprot id: E8T4G8
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS04395
gene id: 648996:THEAM_RS04395
uniprot id: E8T6Q4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

648996:THEAM RS03760
gene id: 648996:THEAM_RS03760
uniprot id: E8T6C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS08325
gene id: 648996:THEAM_RS08325
uniprot id: E8T5E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

648996:THEAM RS06210
gene id: 648996:THEAM_RS06210
uniprot id: E8T2Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

648996:THEAM RS08005
gene id: 648996:THEAM_RS08005
uniprot id: E8T511
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

648996:THEAM RS01085
gene id: 648996:THEAM_RS01085
uniprot id: E8T3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

648996:THEAM RS01800
gene id: 648996:THEAM_RS01800
uniprot id: E8T4Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

648996:THEAM RS04135
gene id: 648996:THEAM_RS04135
uniprot id: E8T6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

648996:THEAM RS04745
gene id: 648996:THEAM_RS04745
uniprot id: E8T214
names: Similarity
messages: Belongs to the GARS family.

648996:THEAM RS00565
gene id: 648996:THEAM_RS00565
uniprot id: E8T381
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

648996:THEAM RS07525
gene id: 648996:THEAM_RS07525
uniprot id: E8T4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS06325
gene id: 648996:THEAM_RS06325
uniprot id: E8T389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

648996:THEAM RS06440
gene id: 648996:THEAM_RS06440
uniprot id: E8T3B1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

648996:THEAM RS03485
gene id: 648996:THEAM_RS03485
uniprot id: E8T672
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

648996:THEAM RS05580
gene id: 648996:THEAM_RS05580
uniprot id: E8T2I3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

648996:THEAM RS00875
gene id: 648996:THEAM_RS00875
uniprot id: E8T3L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

648996:THEAM RS04895
gene id: 648996:THEAM_RS04895
uniprot id: E8T245
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

648996:THEAM RS07655
gene id: 648996:THEAM_RS07655
uniprot id: E8T4M0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

648996:THEAM RS04405
gene id: 648996:THEAM_RS04405
uniprot id: E8T6Q6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

648996:THEAM RS07630
gene id: 648996:THEAM_RS07630
uniprot id: E8T4L5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

648996:THEAM RS07815
gene id: 648996:THEAM_RS07815
uniprot id: E8T4P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

648996:THEAM RS03325
gene id: 648996:THEAM_RS03325
uniprot id: E8T641
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

648996:THEAM RS01890
gene id: 648996:THEAM_RS01890
uniprot id: E8T4S7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

648996:THEAM RS01495
gene id: 648996:THEAM_RS01495
uniprot id: E8T4D1
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS06900
gene id: 648996:THEAM_RS06900
uniprot id: E8T3S4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS01520
gene id: 648996:THEAM_RS01520
uniprot id: E8T4D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

648996:THEAM RS02930
gene id: 648996:THEAM_RS02930
uniprot id: E8T5W5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

648996:THEAM RS08300
gene id: 648996:THEAM_RS08300
uniprot id: E8T5E0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

648996:THEAM RS00430
gene id: 648996:THEAM_RS00430
uniprot id: E8T354
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

648996:THEAM RS02570
gene id: 648996:THEAM_RS02570
uniprot id: E8T5J8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

648996:THEAM RS09790
gene id: 648996:THEAM_RS09790
uniprot id: E8T696
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

648996:THEAM RS07075
gene id: 648996:THEAM_RS07075
uniprot id: E8T435
names: Similarity
messages: Belongs to the YicC/YloC family.

648996:THEAM RS01585
gene id: 648996:THEAM_RS01585
uniprot id: E8T4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

648996:THEAM RS01535
gene id: 648996:THEAM_RS01535
uniprot id: E8T4D8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS03590
gene id: 648996:THEAM_RS03590
uniprot id: E8T693
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

648996:THEAM RS08810
gene id: 648996:THEAM_RS08810
uniprot id: E8T5V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

648996:THEAM RS05495
gene id: 648996:THEAM_RS05495
uniprot id: E8T2G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

648996:THEAM RS01440
gene id: 648996:THEAM_RS01440
uniprot id: E8T4C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

648996:THEAM RS03830
gene id: 648996:THEAM_RS03830
uniprot id: E8T6D7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

648996:THEAM RS04450
gene id: 648996:THEAM_RS04450
uniprot id: E8T1V4
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS01445
gene id: 648996:THEAM_RS01445
uniprot id: E8T4C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

648996:THEAM RS03730
gene id: 648996:THEAM_RS03730
uniprot id: E8T6B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS06480
gene id: 648996:THEAM_RS06480
uniprot id: E8T3B9
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS04415
gene id: 648996:THEAM_RS04415
uniprot id: E8T6Q8
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS01360
gene id: 648996:THEAM_RS01360
uniprot id: E8T429
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

648996:THEAM RS01395
gene id: 648996:THEAM_RS01395
uniprot id: E8T4B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

648996:THEAM RS08450
gene id: 648996:THEAM_RS08450
uniprot id: E8T5G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

648996:THEAM RS07280
gene id: 648996:THEAM_RS07280
uniprot id: E8T475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

648996:THEAM RS07940
gene id: 648996:THEAM_RS07940
uniprot id: E8T4Z8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

648996:THEAM RS05640
gene id: 648996:THEAM_RS05640
uniprot id: E8T2J5
names: Similarity
messages: Belongs to the peptidase A31 family.

648996:THEAM RS07600
gene id: 648996:THEAM_RS07600
uniprot id: E8T4K9
names: Subcellular Location Annotation
messages: Cytoplasm

648996:THEAM RS04835
gene id: 648996:THEAM_RS04835
uniprot id: E8T232
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

648996:THEAM RS04930
gene id: 648996:THEAM_RS04930
uniprot id: E8T252
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

648996:THEAM RS00380
gene id: 648996:THEAM_RS00380
uniprot id: E8T344
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

648996:THEAM RS05000
gene id: 648996:THEAM_RS05000
uniprot id: E8T266
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

648996:THEAM RS02445
gene id: 648996:THEAM_RS02445
uniprot id: E8T5A9
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS06610
gene id: 648996:THEAM_RS06610
uniprot id: E8T3E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

648996:THEAM RS01370
gene id: 648996:THEAM_RS01370
uniprot id: E8T4A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

648996:THEAM RS07295
gene id: 648996:THEAM_RS07295
uniprot id: E8T478
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

648996:THEAM RS05885
gene id: 648996:THEAM_RS05885
uniprot id: E8T2P3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

648996:THEAM RS06660
gene id: 648996:THEAM_RS06660
uniprot id: E8T3F4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS03170
gene id: 648996:THEAM_RS03170
uniprot id: E8T612
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

648996:THEAM RS06795
gene id: 648996:THEAM_RS06795
uniprot id: E8T3Q5
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS08610
gene id: 648996:THEAM_RS08610
uniprot id: E8T5S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

648996:THEAM RS00730
gene id: 648996:THEAM_RS00730
uniprot id: E8T3I4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

648996:THEAM RS03865
gene id: 648996:THEAM_RS03865
uniprot id: E8T6E4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

648996:THEAM RS01100
gene id: 648996:THEAM_RS01100
uniprot id: E8T3X7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

648996:THEAM RS06250
gene id: 648996:THEAM_RS06250
uniprot id: E8T2Z7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

648996:THEAM RS04640
gene id: 648996:THEAM_RS04640
uniprot id: E8T1Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

648996:THEAM RS02980
gene id: 648996:THEAM_RS02980
uniprot id: E8T5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

648996:THEAM RS05335
gene id: 648996:THEAM_RS05335
uniprot id: E8T2D5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

648996:THEAM RS06725
gene id: 648996:THEAM_RS06725
uniprot id: E8T3P0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

648996:THEAM RS09390
gene id: 648996:THEAM_RS09390
uniprot id: E8T562
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS08070
gene id: 648996:THEAM_RS08070
uniprot id: E8T521
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

648996:THEAM RS01990
gene id: 648996:THEAM_RS01990
uniprot id: E8T4U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

648996:THEAM RS05050
gene id: 648996:THEAM_RS05050
uniprot id: E8T277
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS08000
gene id: 648996:THEAM_RS08000
uniprot id: E8T510
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

648996:THEAM RS03735
gene id: 648996:THEAM_RS03735
uniprot id: E8T6B8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

648996:THEAM RS06085
gene id: 648996:THEAM_RS06085
uniprot id: E8T2W3
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

648996:THEAM RS02595
gene id: 648996:THEAM_RS02595
uniprot id: E8T5K3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

648996:THEAM RS04605
gene id: 648996:THEAM_RS04605
uniprot id: E8T1Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

648996:THEAM RS05065
gene id: 648996:THEAM_RS05065
uniprot id: E8T280
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS00055
gene id: 648996:THEAM_RS00055
uniprot id: E8T2R0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

648996:THEAM RS00920
gene id: 648996:THEAM_RS00920
uniprot id: E8T3M0
names: Subcellular Location Annotation
messages: Mitochondrion

648996:THEAM RS01825
gene id: 648996:THEAM_RS01825
uniprot id: E8T4R3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS06375
gene id: 648996:THEAM_RS06375
uniprot id: E8T398
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

648996:THEAM RS09305
gene id: 648996:THEAM_RS09305
uniprot id: E8T6W4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS03710
gene id: 648996:THEAM_RS03710
uniprot id: E8T6B3
names: Similarity
messages: Belongs to the class-I fumarase family.

648996:THEAM RS04205
gene id: 648996:THEAM_RS04205
uniprot id: E8T6L6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS06550
gene id: 648996:THEAM_RS06550
uniprot id: E8T3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

648996:THEAM RS08620
gene id: 648996:THEAM_RS08620
uniprot id: E8T5S2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

648996:THEAM RS07270
gene id: 648996:THEAM_RS07270
uniprot id: E8T473
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

648996:THEAM RS01610
gene id: 648996:THEAM_RS01610
uniprot id: E8T4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

648996:THEAM RS07790
gene id: 648996:THEAM_RS07790
uniprot id: E8T4P6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

648996:THEAM RS07455
gene id: 648996:THEAM_RS07455
uniprot id: E8T4I0
names: Similarity
messages: Belongs to the MEMO1 family.

648996:THEAM RS02745
gene id: 648996:THEAM_RS02745
uniprot id: E8T5N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

648996:THEAM RS03655
gene id: 648996:THEAM_RS03655
uniprot id: E8T6A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

648996:THEAM RS04600
gene id: 648996:THEAM_RS04600
uniprot id: E8T1Y4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

648996:THEAM RS04610
gene id: 648996:THEAM_RS04610
uniprot id: E8T1Y6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

648996:THEAM RS01305
gene id: 648996:THEAM_RS01305
uniprot id: E8T418
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

648996:THEAM RS07735
gene id: 648996:THEAM_RS07735
uniprot id: E8T4N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

648996:THEAM RS08370
gene id: 648996:THEAM_RS08370
uniprot id: E8T5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

648996:THEAM RS08115
gene id: 648996:THEAM_RS08115
uniprot id: E8T530
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

648996:THEAM RS03985
gene id: 648996:THEAM_RS03985
uniprot id: E8T6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

648996:THEAM RS04115
gene id: 648996:THEAM_RS04115
uniprot id: E8T6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

648996:THEAM RS02845
gene id: 648996:THEAM_RS02845
uniprot id: E8T5Q5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

648996:THEAM RS01475
gene id: 648996:THEAM_RS01475
uniprot id: E8T4C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

648996:THEAM RS08530
gene id: 648996:THEAM_RS08530
uniprot id: E8T5H8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

648996:THEAM RS06585
gene id: 648996:THEAM_RS06585
uniprot id: E8T3D9
names: Similarity
messages: Belongs to the UPF0047 family.

648996:THEAM RS02330
gene id: 648996:THEAM_RS02330
uniprot id: E8T586
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

648996:THEAM RS00835
gene id: 648996:THEAM_RS00835
uniprot id: E8T3K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

648996:THEAM RS00750
gene id: 648996:THEAM_RS00750
uniprot id: E8T3I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

648996:THEAM RS01255
gene id: 648996:THEAM_RS01255
uniprot id: E8T408
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

648996:THEAM RS00720
gene id: 648996:THEAM_RS00720
uniprot id: E8T3I2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS05805
gene id: 648996:THEAM_RS05805
uniprot id: E8T2M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS08645
gene id: 648996:THEAM_RS08645
uniprot id: E8T5S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

648996:THEAM RS07390
gene id: 648996:THEAM_RS07390
uniprot id: E8T497
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

648996:THEAM RS01510
gene id: 648996:THEAM_RS01510
uniprot id: E8T4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

648996:THEAM RS02735
gene id: 648996:THEAM_RS02735
uniprot id: E8T5N1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS07540
gene id: 648996:THEAM_RS07540
uniprot id: E8T4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

648996:THEAM RS01940
gene id: 648996:THEAM_RS01940
uniprot id: E8T4T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

648996:THEAM RS07515
gene id: 648996:THEAM_RS07515
uniprot id: E8T4J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

648996:THEAM RS05100
gene id: 648996:THEAM_RS05100
uniprot id: E8T287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

648996:THEAM RS08440
gene id: 648996:THEAM_RS08440
uniprot id: E8T5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

648996:THEAM RS04155
gene id: 648996:THEAM_RS04155
uniprot id: E8T6K6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

648996:THEAM RS06670
gene id: 648996:THEAM_RS06670
uniprot id: E8T3N2
names: Similarity
messages: Belongs to the UPF0434 family.

648996:THEAM RS02225
gene id: 648996:THEAM_RS02225
uniprot id: E8T565
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

648996:THEAM RS01855
gene id: 648996:THEAM_RS01855
uniprot id: E8T4R9
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS08510
gene id: 648996:THEAM_RS08510
uniprot id: E8T5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

648996:THEAM RS03740
gene id: 648996:THEAM_RS03740
uniprot id: E8T6B9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

648996:THEAM RS02400
gene id: 648996:THEAM_RS02400
uniprot id: E8T5A0
names: Similarity
messages: Belongs to the sigma-54 factor family.

648996:THEAM RS03155
gene id: 648996:THEAM_RS03155
uniprot id: E8T609
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

648996:THEAM RS02940
gene id: 648996:THEAM_RS02940
uniprot id: E8T5W7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

648996:THEAM RS01385
gene id: 648996:THEAM_RS01385
uniprot id: E8T4A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

648996:THEAM RS04970
gene id: 648996:THEAM_RS04970
uniprot id: E8T260
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

648996:THEAM RS07650
gene id: 648996:THEAM_RS07650
uniprot id: E8T4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

648996:THEAM RS01230
gene id: 648996:THEAM_RS01230
uniprot id: E8T403
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

648996:THEAM RS07115
gene id: 648996:THEAM_RS07115
uniprot id: E8T443
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

648996:THEAM RS01250
gene id: 648996:THEAM_RS01250
uniprot id: E8T407
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

648996:THEAM RS07960
gene id: 648996:THEAM_RS07960
uniprot id: E8T502
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

648996:THEAM RS07015
gene id: 648996:THEAM_RS07015
uniprot id: E8T3U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

648996:THEAM RS06025
gene id: 648996:THEAM_RS06025
uniprot id: E8T2V1
names: Similarity
messages: Belongs to the ribF family.

648996:THEAM RS01340
gene id: 648996:THEAM_RS01340
uniprot id: E8T425
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

648996:THEAM RS00745
gene id: 648996:THEAM_RS00745
uniprot id: E8T3I7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

648996:THEAM RS06120
gene id: 648996:THEAM_RS06120
uniprot id: E8T2X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

648996:THEAM RS08490
gene id: 648996:THEAM_RS08490
uniprot id: E8T5H1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

648996:THEAM RS08045
gene id: 648996:THEAM_RS08045
uniprot id: E8T516
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

648996:THEAM RS05230
gene id: 648996:THEAM_RS05230
uniprot id: E8T2B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

648996:THEAM RS00680
gene id: 648996:THEAM_RS00680
uniprot id: E8T3H8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

648996:THEAM RS01750
gene id: 648996:THEAM_RS01750
uniprot id: E8T4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

648996:THEAM RS06090
gene id: 648996:THEAM_RS06090
uniprot id: E8T2W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS04955
gene id: 648996:THEAM_RS04955
uniprot id: E8T257
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

648996:THEAM RS05730
gene id: 648996:THEAM_RS05730
uniprot id: E8T2L1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS02680
gene id: 648996:THEAM_RS02680
uniprot id: E8T5M0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

648996:THEAM RS05430
gene id: 648996:THEAM_RS05430
uniprot id: E8T2F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

648996:THEAM RS08485
gene id: 648996:THEAM_RS08485
uniprot id: E8T5H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

648996:THEAM RS00820
gene id: 648996:THEAM_RS00820
uniprot id: E8T3K2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

648996:THEAM RS06320
gene id: 648996:THEAM_RS06320
uniprot id: E8T388
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

648996:THEAM RS03375
gene id: 648996:THEAM_RS03375
uniprot id: E8T650
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

648996:THEAM RS05225
gene id: 648996:THEAM_RS05225
uniprot id: E8T2B3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

648996:THEAM RS03255
gene id: 648996:THEAM_RS03255
uniprot id: E8T627
names: Similarity
messages: Belongs to the UPF0758 family.

648996:THEAM RS05455
gene id: 648996:THEAM_RS05455
uniprot id: E8T2F8
names: Similarity
messages: Belongs to the MotB family.

648996:THEAM RS04765
gene id: 648996:THEAM_RS04765
uniprot id: E8T218
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS08255
gene id: 648996:THEAM_RS08255
uniprot id: E8T5D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

648996:THEAM RS04980
gene id: 648996:THEAM_RS04980
uniprot id: E8T262
names: Similarity
messages: Belongs to the GSP E family.

648996:THEAM RS01745
gene id: 648996:THEAM_RS01745
uniprot id: E8T4H4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

648996:THEAM RS04660
gene id: 648996:THEAM_RS04660
uniprot id: E8T1Z6
names: Similarity
messages: Belongs to the HypD family.

648996:THEAM RS01185
gene id: 648996:THEAM_RS01185
uniprot id: E8T3Z4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

648996:THEAM RS01945
gene id: 648996:THEAM_RS01945
uniprot id: E8T4T9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

648996:THEAM RS08185
gene id: 648996:THEAM_RS08185
uniprot id: E8T545
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

648996:THEAM RS06880
gene id: 648996:THEAM_RS06880
uniprot id: E8T3S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

648996:THEAM RS02365
gene id: 648996:THEAM_RS02365
uniprot id: E8T593
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS08220
gene id: 648996:THEAM_RS08220
uniprot id: E8T5C9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

648996:THEAM RS02715
gene id: 648996:THEAM_RS02715
uniprot id: E8T5M7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

648996:THEAM RS03770
gene id: 648996:THEAM_RS03770
uniprot id: E8T6C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS04445
gene id: 648996:THEAM_RS04445
uniprot id: E8T1V3
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS00345
gene id: 648996:THEAM_RS00345
uniprot id: E8T337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS05120
gene id: 648996:THEAM_RS05120
uniprot id: E8T291
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

648996:THEAM RS07745
gene id: 648996:THEAM_RS07745
uniprot id: E8T4N8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS01905
gene id: 648996:THEAM_RS01905
uniprot id: E8T4T0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

648996:THEAM RS02950
gene id: 648996:THEAM_RS02950
uniprot id: E8T5W9
names: Similarity
messages: Belongs to the histone deacetylase family.

648996:THEAM RS03095
gene id: 648996:THEAM_RS03095
uniprot id: E8T5Z7
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

648996:THEAM RS06105
gene id: 648996:THEAM_RS06105
uniprot id: E8T2W7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

648996:THEAM RS06905
gene id: 648996:THEAM_RS06905
uniprot id: E8T3S5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

648996:THEAM RS07190
gene id: 648996:THEAM_RS07190
uniprot id: E8T458
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

648996:THEAM RS04350
gene id: 648996:THEAM_RS04350
uniprot id: E8T6P5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

648996:THEAM RS05815
gene id: 648996:THEAM_RS05815
uniprot id: E8T2M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

648996:THEAM RS01400
gene id: 648996:THEAM_RS01400
uniprot id: E8T4B2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

648996:THEAM RS01965
gene id: 648996:THEAM_RS01965
uniprot id: E8T4U2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

648996:THEAM RS03355
gene id: 648996:THEAM_RS03355
uniprot id: E8T646
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS05680
gene id: 648996:THEAM_RS05680
uniprot id: E8T2K3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

648996:THEAM RS08425
gene id: 648996:THEAM_RS08425
uniprot id: E8T5F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

648996:THEAM RS06080
gene id: 648996:THEAM_RS06080
uniprot id: E8T2W2
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

648996:THEAM RS00360
gene id: 648996:THEAM_RS00360
uniprot id: E8T340
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

648996:THEAM RS06275
gene id: 648996:THEAM_RS06275
uniprot id: E8T302
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

648996:THEAM RS04975
gene id: 648996:THEAM_RS04975
uniprot id: E8T261
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

648996:THEAM RS01425
gene id: 648996:THEAM_RS01425
uniprot id: E8T4B7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

648996:THEAM RS02355
gene id: 648996:THEAM_RS02355
uniprot id: E8T591
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

648996:THEAM RS01715
gene id: 648996:THEAM_RS01715
uniprot id: E8T4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

648996:THEAM RS06270
gene id: 648996:THEAM_RS06270
uniprot id: E8T301
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

648996:THEAM RS09640
gene id: 648996:THEAM_RS09640
uniprot id: E8T4X2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

648996:THEAM RS00685
gene id: 648996:THEAM_RS00685
uniprot id: E8T3H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

648996:THEAM RS05460
gene id: 648996:THEAM_RS05460
uniprot id: E8T2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

648996:THEAM RS00450
gene id: 648996:THEAM_RS00450
uniprot id: E8T358
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04910
gene id: 648996:THEAM_RS04910
uniprot id: E8T248
names: Similarity
messages: Belongs to the phosphohexose mutase family.

648996:THEAM RS08720
gene id: 648996:THEAM_RS08720
uniprot id: E8T5U2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

648996:THEAM RS06875
gene id: 648996:THEAM_RS06875
uniprot id: E8T3S0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

648996:THEAM RS00870
gene id: 648996:THEAM_RS00870
uniprot id: E8T3K9
names: Function
messages: Putative RNA ligase (PubMed:25324547). Is able to catalyze the adenylation reaction of ssDNA 3'-terminal phosphate (ssDNA 3'p) to 3'-adenylated DNA (ssDNA 3'pp5'A) (PubMed:25324547).

648996:THEAM RS04530
gene id: 648996:THEAM_RS04530
uniprot id: E8T1X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS04760
gene id: 648996:THEAM_RS04760
uniprot id: E8T217
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

648996:THEAM RS01295
gene id: 648996:THEAM_RS01295
uniprot id: E8T416
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

648996:THEAM RS02775
gene id: 648996:THEAM_RS02775
uniprot id: E8T5P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

648996:THEAM RS06420
gene id: 648996:THEAM_RS06420
uniprot id: E8T3A7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

648996:THEAM RS07395
gene id: 648996:THEAM_RS07395
uniprot id: E8T498
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

648996:THEAM RS01290
gene id: 648996:THEAM_RS01290
uniprot id: E8T415
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

648996:THEAM RS04345
gene id: 648996:THEAM_RS04345
uniprot id: E8T6P4
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS00660
gene id: 648996:THEAM_RS00660
uniprot id: E8T3H4
names: Similarity
messages: Belongs to the YggT family.

648996:THEAM RS01045
gene id: 648996:THEAM_RS01045
uniprot id: E8T3W6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

648996:THEAM RS07660
gene id: 648996:THEAM_RS07660
uniprot id: E8T4M1
names: Similarity
messages: Belongs to the universal stress protein A family.

648996:THEAM RS03765
gene id: 648996:THEAM_RS03765
uniprot id: E8T6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS05005
gene id: 648996:THEAM_RS05005
uniprot id: E8T267
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

648996:THEAM RS07850
gene id: 648996:THEAM_RS07850
uniprot id: E8T4Y2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

648996:THEAM RS01180
gene id: 648996:THEAM_RS01180
uniprot id: E8T3Z3
names: Similarity
messages: Belongs to the UbiD family.

648996:THEAM RS01405
gene id: 648996:THEAM_RS01405
uniprot id: E8T4B3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

648996:THEAM RS01485
gene id: 648996:THEAM_RS01485
uniprot id: E8T4C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

648996:THEAM RS04225
gene id: 648996:THEAM_RS04225
uniprot id: E8T6M0
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS00925
gene id: 648996:THEAM_RS00925
uniprot id: E8T3M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

648996:THEAM RS01840
gene id: 648996:THEAM_RS01840
uniprot id: E8T4R6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS05570
gene id: 648996:THEAM_RS05570
uniprot id: E8T2I1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

648996:THEAM RS04830
gene id: 648996:THEAM_RS04830
uniprot id: E8T231
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS00030
gene id: 648996:THEAM_RS00030
uniprot id: E8T2Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

648996:THEAM RS08170
gene id: 648996:THEAM_RS08170
uniprot id: E8T542
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

648996:THEAM RS05700
gene id: 648996:THEAM_RS05700
uniprot id: E8T2K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

648996:THEAM RS02690
gene id: 648996:THEAM_RS02690
uniprot id: E8T5M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

648996:THEAM RS03055
gene id: 648996:THEAM_RS03055
uniprot id: E8T5Y9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

648996:THEAM RS05350
gene id: 648996:THEAM_RS05350
uniprot id: E8T2D8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

648996:THEAM RS05605
gene id: 648996:THEAM_RS05605
uniprot id: E8T2I8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

648996:THEAM RS04555
gene id: 648996:THEAM_RS04555
uniprot id: E8T1X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane

648996:THEAM RS06430
gene id: 648996:THEAM_RS06430
uniprot id: E8T3A9
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS02250
gene id: 648996:THEAM_RS02250
uniprot id: E8T570
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

648996:THEAM RS03780
gene id: 648996:THEAM_RS03780
uniprot id: E8T6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

648996:THEAM RS04655
gene id: 648996:THEAM_RS04655
uniprot id: E8T1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

648996:THEAM RS09280
gene id: 648996:THEAM_RS09280
uniprot id: E8T6V8
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

648996:THEAM RS01805
gene id: 648996:THEAM_RS01805
uniprot id: E8T4Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS05600
gene id: 648996:THEAM_RS05600
uniprot id: E8T2I7
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

648996:THEAM RS04120
gene id: 648996:THEAM_RS04120
uniprot id: E8T6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

648996:THEAM RS00670
gene id: 648996:THEAM_RS00670
uniprot id: E8T3H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

648996:THEAM RS05085
gene id: 648996:THEAM_RS05085
uniprot id: E8T284
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

648996:THEAM RS07800
gene id: 648996:THEAM_RS07800
uniprot id: E8T4P7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

648996:THEAM RS06540
gene id: 648996:THEAM_RS06540
uniprot id: E8T3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

648996:THEAM RS07995
gene id: 648996:THEAM_RS07995
uniprot id: E8T509
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

648996:THEAM RS09175
gene id: 648996:THEAM_RS09175
uniprot id: E8T6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

648996:THEAM RS05905
gene id: 648996:THEAM_RS05905
uniprot id: E8T2P6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS00485
gene id: 648996:THEAM_RS00485
uniprot id: E8T365
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS03240
gene id: 648996:THEAM_RS03240
uniprot id: E8T624
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

648996:THEAM RS07160
gene id: 648996:THEAM_RS07160
uniprot id: E8T452
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS05320
gene id: 648996:THEAM_RS05320
uniprot id: E8T2D2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

648996:THEAM RS05675
gene id: 648996:THEAM_RS05675
uniprot id: E8T2K2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

648996:THEAM RS04590
gene id: 648996:THEAM_RS04590
uniprot id: E8T1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

648996:THEAM RS03315
gene id: 648996:THEAM_RS03315
uniprot id: E8T639
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

648996:THEAM RS01345
gene id: 648996:THEAM_RS01345
uniprot id: E8T426
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

648996:THEAM RS08605
gene id: 648996:THEAM_RS08605
uniprot id: E8T5R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

648996:THEAM RS02540
gene id: 648996:THEAM_RS02540
uniprot id: E8T5J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

648996:THEAM RS00495
gene id: 648996:THEAM_RS00495
uniprot id: E8T367
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

648996:THEAM RS07530
gene id: 648996:THEAM_RS07530
uniprot id: E8T4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS02695
gene id: 648996:THEAM_RS02695
uniprot id: E8T5M3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

648996:THEAM RS05930
gene id: 648996:THEAM_RS05930
uniprot id: E8T2T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

648996:THEAM RS07915
gene id: 648996:THEAM_RS07915
uniprot id: E8T4Z3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS03785
gene id: 648996:THEAM_RS03785
uniprot id: E8T6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS03650
gene id: 648996:THEAM_RS03650
uniprot id: E8T6A1
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

648996:THEAM RS03525
gene id: 648996:THEAM_RS03525
uniprot id: E8T681
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Molecular chaperone capable of stabilizing a range of proteins.

648996:THEAM RS00935
gene id: 648996:THEAM_RS00935
uniprot id: E8T3M3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

648996:THEAM RS04130
gene id: 648996:THEAM_RS04130
uniprot id: E8T6K1
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS05110
gene id: 648996:THEAM_RS05110
uniprot id: E8T289
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

648996:THEAM RS06065
gene id: 648996:THEAM_RS06065
uniprot id: E8T2V9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

648996:THEAM RS07325
gene id: 648996:THEAM_RS07325
uniprot id: E8T484
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

648996:THEAM RS05195
gene id: 648996:THEAM_RS05195
uniprot id: E8T2A6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS05070
gene id: 648996:THEAM_RS05070
uniprot id: E8T281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

648996:THEAM RS07625
gene id: 648996:THEAM_RS07625
uniprot id: E8T4L4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

648996:THEAM RS06400
gene id: 648996:THEAM_RS06400
uniprot id: E8T3A3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

648996:THEAM RS04300
gene id: 648996:THEAM_RS04300
uniprot id: E8T6N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

648996:THEAM RS03665
gene id: 648996:THEAM_RS03665
uniprot id: E8T6A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

648996:THEAM RS06530
gene id: 648996:THEAM_RS06530
uniprot id: E8T3C8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

648996:THEAM RS02600
gene id: 648996:THEAM_RS02600
uniprot id: E8T5K4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

648996:THEAM RS09170
gene id: 648996:THEAM_RS09170
uniprot id: E8T6T2
names: Similarity
messages: Belongs to the GSP E family.

648996:THEAM RS07060
gene id: 648996:THEAM_RS07060
uniprot id: E8T432
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

648996:THEAM RS02020
gene id: 648996:THEAM_RS02020
uniprot id: E8T4V3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

648996:THEAM RS02610
gene id: 648996:THEAM_RS02610
uniprot id: E8T5K6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04500
gene id: 648996:THEAM_RS04500
uniprot id: E8T1W4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

648996:THEAM RS00475
gene id: 648996:THEAM_RS00475
uniprot id: E8T363
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

648996:THEAM RS03370
gene id: 648996:THEAM_RS03370
uniprot id: E8T649
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS00795
gene id: 648996:THEAM_RS00795
uniprot id: E8T3J7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

648996:THEAM RS05490
gene id: 648996:THEAM_RS05490
uniprot id: E8T2G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

648996:THEAM RS01505
gene id: 648996:THEAM_RS01505
uniprot id: E8T4D3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

648996:THEAM RS05565
gene id: 648996:THEAM_RS05565
uniprot id: E8T2I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

648996:THEAM RS01005
gene id: 648996:THEAM_RS01005
uniprot id: E8T3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

648996:THEAM RS06140
gene id: 648996:THEAM_RS06140
uniprot id: E8T2X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS02890
gene id: 648996:THEAM_RS02890
uniprot id: E8T5R6
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

648996:THEAM RS08670
gene id: 648996:THEAM_RS08670
uniprot id: E8T5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

648996:THEAM RS08570
gene id: 648996:THEAM_RS08570
uniprot id: E8T5I4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

648996:THEAM RS08745
gene id: 648996:THEAM_RS08745
uniprot id: E8T5U7
names: Similarity
messages: Belongs to the TlyA family.

648996:THEAM RS03005
gene id: 648996:THEAM_RS03005
uniprot id: E8T5Y0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

648996:THEAM RS05670
gene id: 648996:THEAM_RS05670
uniprot id: E8T2K1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

648996:THEAM RS00765
gene id: 648996:THEAM_RS00765
uniprot id: E8T3J1
names: Similarity
messages: Belongs to the peptidase S41A family.

648996:THEAM RS07365
gene id: 648996:THEAM_RS07365
uniprot id: E8T492
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

648996:THEAM RS04510
gene id: 648996:THEAM_RS04510
uniprot id: E8T1W6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

648996:THEAM RS07225
gene id: 648996:THEAM_RS07225
uniprot id: E8T465
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

648996:THEAM RS00550
gene id: 648996:THEAM_RS00550
uniprot id: E8T378
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

648996:THEAM RS04900
gene id: 648996:THEAM_RS04900
uniprot id: E8T246
names: Similarity
messages: Belongs to the GPI family.

648996:THEAM RS08090
gene id: 648996:THEAM_RS08090
uniprot id: E8T525
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS02520
gene id: 648996:THEAM_RS02520
uniprot id: E8T5C4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

648996:THEAM RS00910
gene id: 648996:THEAM_RS00910
uniprot id: E8T3L8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

648996:THEAM RS07580
gene id: 648996:THEAM_RS07580
uniprot id: E8T4K5
names: Subcellular Location Annotation
messages: Cytoplasm

648996:THEAM RS01410
gene id: 648996:THEAM_RS01410
uniprot id: E8T4B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

648996:THEAM RS04140
gene id: 648996:THEAM_RS04140
uniprot id: E8T6K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

648996:THEAM RS00845
gene id: 648996:THEAM_RS00845
uniprot id: E8T3K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

648996:THEAM RS01550
gene id: 648996:THEAM_RS01550
uniprot id: E8T4E1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

648996:THEAM RS06640
gene id: 648996:THEAM_RS06640
uniprot id: E8T3F0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

648996:THEAM RS03880
gene id: 648996:THEAM_RS03880
uniprot id: E8T6E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

648996:THEAM RS07305
gene id: 648996:THEAM_RS07305
uniprot id: E8T480
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

648996:THEAM RS06535
gene id: 648996:THEAM_RS06535
uniprot id: E8T3C9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

648996:THEAM RS03695
gene id: 648996:THEAM_RS03695
uniprot id: E8T6B0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

648996:THEAM RS01790
gene id: 648996:THEAM_RS01790
uniprot id: E8T4Q6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

648996:THEAM RS01575
gene id: 648996:THEAM_RS01575
uniprot id: E8T4E6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

648996:THEAM RS06370
gene id: 648996:THEAM_RS06370
uniprot id: E8T397
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS05095
gene id: 648996:THEAM_RS05095
uniprot id: E8T286
names: Similarity
messages: Belongs to the UPF0047 family.

648996:THEAM RS00930
gene id: 648996:THEAM_RS00930
uniprot id: E8T3M2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

648996:THEAM RS07975
gene id: 648996:THEAM_RS07975
uniprot id: E8T505
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

648996:THEAM RS02305
gene id: 648996:THEAM_RS02305
uniprot id: E8T581
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

648996:THEAM RS06665
gene id: 648996:THEAM_RS06665
uniprot id: E8T3F5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

648996:THEAM RS01820
gene id: 648996:THEAM_RS01820
uniprot id: E8T4R2
names: Similarity
messages: Belongs to the UPF0173 family.

648996:THEAM RS01480
gene id: 648996:THEAM_RS01480
uniprot id: E8T4C8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

648996:THEAM RS00335
gene id: 648996:THEAM_RS00335
uniprot id: E8T335
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

648996:THEAM RS05990
gene id: 648996:THEAM_RS05990
uniprot id: E8T2U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

648996:THEAM RS08525
gene id: 648996:THEAM_RS08525
uniprot id: E8T5H7
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

648996:THEAM RS01310
gene id: 648996:THEAM_RS01310
uniprot id: E8T419
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

648996:THEAM RS07290
gene id: 648996:THEAM_RS07290
uniprot id: E8T477
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

648996:THEAM RS01325
gene id: 648996:THEAM_RS01325
uniprot id: E8T422
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

648996:THEAM RS08680
gene id: 648996:THEAM_RS08680
uniprot id: E8T5T4
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS02425
gene id: 648996:THEAM_RS02425
uniprot id: E8T5A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

648996:THEAM RS00950
gene id: 648996:THEAM_RS00950
uniprot id: E8T3M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

648996:THEAM RS07560
gene id: 648996:THEAM_RS07560
uniprot id: E8T4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

648996:THEAM RS08635
gene id: 648996:THEAM_RS08635
uniprot id: E8T5S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS04325
gene id: 648996:THEAM_RS04325
uniprot id: E8T6P0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

648996:THEAM RS06145
gene id: 648996:THEAM_RS06145
uniprot id: E8T2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

648996:THEAM RS02255
gene id: 648996:THEAM_RS02255
uniprot id: E8T571
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

648996:THEAM RS05550
gene id: 648996:THEAM_RS05550
uniprot id: E8T2H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS02590
gene id: 648996:THEAM_RS02590
uniprot id: E8T5K2
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

648996:THEAM RS07180
gene id: 648996:THEAM_RS07180
uniprot id: E8T456
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

648996:THEAM RS05685
gene id: 648996:THEAM_RS05685
uniprot id: E8T2K4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

648996:THEAM RS05355
gene id: 648996:THEAM_RS05355
uniprot id: E8T2D9
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.

648996:THEAM RS01950
gene id: 648996:THEAM_RS01950
uniprot id: E8T4U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

648996:THEAM RS05710
gene id: 648996:THEAM_RS05710
uniprot id: E8T2K7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

648996:THEAM RS03915
gene id: 648996:THEAM_RS03915
uniprot id: E8T6F5
names: Similarity
messages: Belongs to the peptidase U62 family.

648996:THEAM RS00385
gene id: 648996:THEAM_RS00385
uniprot id: E8T345
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

648996:THEAM RS01470
gene id: 648996:THEAM_RS01470
uniprot id: E8T4C6
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

648996:THEAM RS07925
gene id: 648996:THEAM_RS07925
uniprot id: E8T4Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

648996:THEAM RS07690
gene id: 648996:THEAM_RS07690
uniprot id: E8T4M8
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS03195
gene id: 648996:THEAM_RS03195
uniprot id: E8T617
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

648996:THEAM RS03425
gene id: 648996:THEAM_RS03425
uniprot id: E8T660
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

648996:THEAM RS04890
gene id: 648996:THEAM_RS04890
uniprot id: E8T244
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

648996:THEAM RS03795
gene id: 648996:THEAM_RS03795
uniprot id: E8T6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

648996:THEAM RS04635
gene id: 648996:THEAM_RS04635
uniprot id: E8T1Z1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

648996:THEAM RS01455
gene id: 648996:THEAM_RS01455
uniprot id: E8T4C3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

648996:THEAM RS03775
gene id: 648996:THEAM_RS03775
uniprot id: E8T6C6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS02755
gene id: 648996:THEAM_RS02755
uniprot id: E8T5N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

648996:THEAM RS00650
gene id: 648996:THEAM_RS00650
uniprot id: E8T3H2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

648996:THEAM RS06695
gene id: 648996:THEAM_RS06695
uniprot id: E8T3N4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

648996:THEAM RS08795
gene id: 648996:THEAM_RS08795
uniprot id: E8T5V6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04175
gene id: 648996:THEAM_RS04175
uniprot id: E8T6L0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS05295
gene id: 648996:THEAM_RS05295
uniprot id: E8T2C7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

648996:THEAM RS00640
gene id: 648996:THEAM_RS00640
uniprot id: E8T3H0
names: Similarity
messages: Belongs to the peptidase S26 family.

648996:THEAM RS08140
gene id: 648996:THEAM_RS08140
uniprot id: E8T535
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

648996:THEAM RS03975
gene id: 648996:THEAM_RS03975
uniprot id: E8T6G9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

648996:THEAM RS06490
gene id: 648996:THEAM_RS06490
uniprot id: E8T3C1
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS07680
gene id: 648996:THEAM_RS07680
uniprot id: E8T4M6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS08420
gene id: 648996:THEAM_RS08420
uniprot id: E8T5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

648996:THEAM RS01920
gene id: 648996:THEAM_RS01920
uniprot id: E8T4T4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

648996:THEAM RS02530
gene id: 648996:THEAM_RS02530
uniprot id: E8T5C6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04645
gene id: 648996:THEAM_RS04645
uniprot id: E8T1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

648996:THEAM RS02240
gene id: 648996:THEAM_RS02240
uniprot id: E8T568
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

648996:THEAM RS02055
gene id: 648996:THEAM_RS02055
uniprot id: E8T4W0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

648996:THEAM RS04940
gene id: 648996:THEAM_RS04940
uniprot id: E8T254
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

648996:THEAM RS04570
gene id: 648996:THEAM_RS04570
uniprot id: E8T1X8
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

648996:THEAM RS03680
gene id: 648996:THEAM_RS03680
uniprot id: E8T6A7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

648996:THEAM RS05630
gene id: 648996:THEAM_RS05630
uniprot id: E8T2J3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

648996:THEAM RS02190
gene id: 648996:THEAM_RS02190
uniprot id: E8T558
names: Subcellular Location Annotation
messages: Cytoplasm

648996:THEAM RS03090
gene id: 648996:THEAM_RS03090
uniprot id: E8T5Z6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

648996:THEAM RS05715
gene id: 648996:THEAM_RS05715
uniprot id: E8T2K8
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS06720
gene id: 648996:THEAM_RS06720
uniprot id: E8T3N9
names: Similarity
messages: Belongs to the ycf81 family.

648996:THEAM RS06295
gene id: 648996:THEAM_RS06295
uniprot id: E8T383
names: Similarity
messages: Belongs to the Skp family.

648996:THEAM RS04195
gene id: 648996:THEAM_RS04195
uniprot id: E8T6L4
names: Subunit
messages: Homodimer.

648996:THEAM RS02880
gene id: 648996:THEAM_RS02880
uniprot id: E8T5R3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS02420
gene id: 648996:THEAM_RS02420
uniprot id: E8T5A4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

648996:THEAM RS02320
gene id: 648996:THEAM_RS02320
uniprot id: E8T584
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

648996:THEAM RS08150
gene id: 648996:THEAM_RS08150
uniprot id: E8T537
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

648996:THEAM RS07495
gene id: 648996:THEAM_RS07495
uniprot id: E8T4I8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS05575
gene id: 648996:THEAM_RS05575
uniprot id: E8T2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

648996:THEAM RS04305
gene id: 648996:THEAM_RS04305
uniprot id: E8T6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

648996:THEAM RS04520
gene id: 648996:THEAM_RS04520
uniprot id: E8T1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

648996:THEAM RS00050
gene id: 648996:THEAM_RS00050
uniprot id: E8T2Q9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

648996:THEAM RS03280
gene id: 648996:THEAM_RS03280
uniprot id: E8T632
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS06395
gene id: 648996:THEAM_RS06395
uniprot id: E8T3A2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

648996:THEAM RS07835
gene id: 648996:THEAM_RS07835
uniprot id: E8T4X9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

648996:THEAM RS03365
gene id: 648996:THEAM_RS03365
uniprot id: E8T648
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

648996:THEAM RS01690
gene id: 648996:THEAM_RS01690
uniprot id: E8T4G5
names: Similarity
messages: Belongs to the glutamate synthase family.

648996:THEAM RS00605
gene id: 648996:THEAM_RS00605
uniprot id: E8T3G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

648996:THEAM RS03720
gene id: 648996:THEAM_RS03720
uniprot id: E8T6B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS07670
gene id: 648996:THEAM_RS07670
uniprot id: E8T4M3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

648996:THEAM RS07510
gene id: 648996:THEAM_RS07510
uniprot id: E8T4J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

648996:THEAM RS01350
gene id: 648996:THEAM_RS01350
uniprot id: E8T427
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

648996:THEAM RS07055
gene id: 648996:THEAM_RS07055
uniprot id: E8T431
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

648996:THEAM RS00945
gene id: 648996:THEAM_RS00945
uniprot id: E8T3M5
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS04905
gene id: 648996:THEAM_RS04905
uniprot id: E8T247
names: Similarity
messages: Belongs to the CFA/CMAS family.

648996:THEAM RS07780
gene id: 648996:THEAM_RS07780
uniprot id: E8T4P4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

648996:THEAM RS04990
gene id: 648996:THEAM_RS04990
uniprot id: E8T264
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

648996:THEAM RS03275
gene id: 648996:THEAM_RS03275
uniprot id: E8T631
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

648996:THEAM RS01910
gene id: 648996:THEAM_RS01910
uniprot id: E8T4T2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

648996:THEAM RS07425
gene id: 648996:THEAM_RS07425
uniprot id: E8T4A3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

648996:THEAM RS05185
gene id: 648996:THEAM_RS05185
uniprot id: E8T2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

648996:THEAM RS03065
gene id: 648996:THEAM_RS03065
uniprot id: E8T5Z1
names: Similarity
messages: Belongs to the class-I fumarase family.

648996:THEAM RS00810
gene id: 648996:THEAM_RS00810
uniprot id: E8T3K0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

648996:THEAM RS09495
gene id: 648996:THEAM_RS09495
uniprot id: E8T4Z2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

648996:THEAM RS02015
gene id: 648996:THEAM_RS02015
uniprot id: E8T4V2
names: Similarity
messages: Belongs to the hemerythrin family.

648996:THEAM RS01450
gene id: 648996:THEAM_RS01450
uniprot id: E8T4C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

648996:THEAM RS00980
gene id: 648996:THEAM_RS00980
uniprot id: E8T3V3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

648996:THEAM RS01260
gene id: 648996:THEAM_RS01260
uniprot id: E8T409
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

648996:THEAM RS00535
gene id: 648996:THEAM_RS00535
uniprot id: E8T375
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

648996:THEAM RS01605
gene id: 648996:THEAM_RS01605
uniprot id: E8T4F2
names: Similarity
messages: Belongs to the PstS family.

648996:THEAM RS02375
gene id: 648996:THEAM_RS02375
uniprot id: E8T595
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

648996:THEAM RS05625
gene id: 648996:THEAM_RS05625
uniprot id: E8T2J2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

648996:THEAM RS07230
gene id: 648996:THEAM_RS07230
uniprot id: E8T466
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

648996:THEAM RS01435
gene id: 648996:THEAM_RS01435
uniprot id: E8T4B9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

648996:THEAM RS06150
gene id: 648996:THEAM_RS06150
uniprot id: E8T2X6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

648996:THEAM RS00725
gene id: 648996:THEAM_RS00725
uniprot id: E8T3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

648996:THEAM RS08540
gene id: 648996:THEAM_RS08540
uniprot id: E8T5H9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

648996:THEAM RS06285
gene id: 648996:THEAM_RS06285
uniprot id: E8T304
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

648996:THEAM RS03105
gene id: 648996:THEAM_RS03105
uniprot id: E8T5Z9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

648996:THEAM RS08375
gene id: 648996:THEAM_RS08375
uniprot id: E8T5E9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

648996:THEAM RS09475
gene id: 648996:THEAM_RS09475
uniprot id: E8T496
names: Subcellular Location Annotation
messages: Periplasm

648996:THEAM RS08245
gene id: 648996:THEAM_RS08245
uniprot id: E8T5D4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

648996:THEAM RS00490
gene id: 648996:THEAM_RS00490
uniprot id: E8T366
names: Similarity
messages: Belongs to the CutA family.

648996:THEAM RS01055
gene id: 648996:THEAM_RS01055
uniprot id: E8T3W8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

648996:THEAM RS04755
gene id: 648996:THEAM_RS04755
uniprot id: E8T216
names: Similarity
messages: Belongs to the peptidase S49 family.

648996:THEAM RS07335
gene id: 648996:THEAM_RS07335
uniprot id: E8T486
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

648996:THEAM RS03490
gene id: 648996:THEAM_RS03490
uniprot id: E8T673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS01465
gene id: 648996:THEAM_RS01465
uniprot id: E8T4C5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

648996:THEAM RS00985
gene id: 648996:THEAM_RS00985
uniprot id: E8T3V4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

648996:THEAM RS00035
gene id: 648996:THEAM_RS00035
uniprot id: E8T2Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

648996:THEAM RS06015
gene id: 648996:THEAM_RS06015
uniprot id: E8T2U9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

648996:THEAM RS01490
gene id: 648996:THEAM_RS01490
uniprot id: E8T4D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

648996:THEAM RS02575
gene id: 648996:THEAM_RS02575
uniprot id: E8T5J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

648996:THEAM RS03585
gene id: 648996:THEAM_RS03585
uniprot id: E8T692
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

648996:THEAM RS04920
gene id: 648996:THEAM_RS04920
uniprot id: E8T250
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

648996:THEAM RS05920
gene id: 648996:THEAM_RS05920
uniprot id: E8T2P9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

648996:THEAM RS08800
gene id: 648996:THEAM_RS08800
uniprot id: E8T5V7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

648996:THEAM RS08040
gene id: 648996:THEAM_RS08040
uniprot id: E8T515
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

648996:THEAM RS04475
gene id: 648996:THEAM_RS04475
uniprot id: E8T1V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

648996:THEAM RS01390
gene id: 648996:THEAM_RS01390
uniprot id: E8T4B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

648996:THEAM RS05880
gene id: 648996:THEAM_RS05880
uniprot id: E8T2P2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

648996:THEAM RS07430
gene id: 648996:THEAM_RS07430
uniprot id: E8T4A4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

648996:THEAM RS03560
gene id: 648996:THEAM_RS03560
uniprot id: E8T687
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

648996:THEAM RS00410
gene id: 648996:THEAM_RS00410
uniprot id: E8T350
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

648996:THEAM RS08590
gene id: 648996:THEAM_RS08590
uniprot id: E8T5I8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

648996:THEAM RS06690
gene id: 648996:THEAM_RS06690
uniprot id: E8T3N3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS08480
gene id: 648996:THEAM_RS08480
uniprot id: E8T5G9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

648996:THEAM RS05960
gene id: 648996:THEAM_RS05960
uniprot id: E8T2U3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

648996:THEAM RS00960
gene id: 648996:THEAM_RS00960
uniprot id: E8T3M8
names: Similarity
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.

648996:THEAM RS03505
gene id: 648996:THEAM_RS03505
uniprot id: E8T676
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

648996:THEAM RS06435
gene id: 648996:THEAM_RS06435
uniprot id: E8T3B0
names: Similarity
messages: Belongs to the pyruvate kinase family.

648996:THEAM RS03755
gene id: 648996:THEAM_RS03755
uniprot id: E8T6C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

648996:THEAM RS05060
gene id: 648996:THEAM_RS05060
uniprot id: E8T279
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS06215
gene id: 648996:THEAM_RS06215
uniprot id: E8T2Z0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

648996:THEAM RS02100
gene id: 648996:THEAM_RS02100
uniprot id: E8T4W7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

648996:THEAM RS06020
gene id: 648996:THEAM_RS06020
uniprot id: E8T2V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

648996:THEAM RS02665
gene id: 648996:THEAM_RS02665
uniprot id: E8T5L7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

648996:THEAM RS00610
gene id: 648996:THEAM_RS00610
uniprot id: E8T3G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

648996:THEAM RS04045
gene id: 648996:THEAM_RS04045
uniprot id: E8T6I3
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

648996:THEAM RS07085
gene id: 648996:THEAM_RS07085
uniprot id: E8T437
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

648996:THEAM RS02975
gene id: 648996:THEAM_RS02975
uniprot id: E8T5X4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

648996:THEAM RS07715
gene id: 648996:THEAM_RS07715
uniprot id: E8T4N1
names: Cofactor
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

648996:THEAM RS00940
gene id: 648996:THEAM_RS00940
uniprot id: E8T3M4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

648996:THEAM RS04125
gene id: 648996:THEAM_RS04125
uniprot id: E8T6K0
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS02935
gene id: 648996:THEAM_RS02935
uniprot id: E8T5W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

648996:THEAM RS02345
gene id: 648996:THEAM_RS02345
uniprot id: E8T589
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

648996:THEAM RS06075
gene id: 648996:THEAM_RS06075
uniprot id: E8T2W1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

648996:THEAM RS05595
gene id: 648996:THEAM_RS05595
uniprot id: E8T2I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

648996:THEAM RS04725
gene id: 648996:THEAM_RS04725
uniprot id: E8T210
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

648996:THEAM RS06885
gene id: 648996:THEAM_RS06885
uniprot id: E8T3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

648996:THEAM RS01320
gene id: 648996:THEAM_RS01320
uniprot id: E8T421
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

648996:THEAM RS07355
gene id: 648996:THEAM_RS07355
uniprot id: E8T490
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

648996:THEAM RS01215
gene id: 648996:THEAM_RS01215
uniprot id: E8T400
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

648996:THEAM RS02895
gene id: 648996:THEAM_RS02895
uniprot id: E8T5R7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

648996:THEAM RS01930
gene id: 648996:THEAM_RS01930
uniprot id: E8T4T6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

648996:THEAM RS05850
gene id: 648996:THEAM_RS05850
uniprot id: E8T2N5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

648996:THEAM RS03845
gene id: 648996:THEAM_RS03845
uniprot id: E8T6E0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS02025
gene id: 648996:THEAM_RS02025
uniprot id: E8T4V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

648996:THEAM RS07620
gene id: 648996:THEAM_RS07620
uniprot id: E8T4L3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

648996:THEAM RS06060
gene id: 648996:THEAM_RS06060
uniprot id: E8T2V8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

648996:THEAM RS05140
gene id: 648996:THEAM_RS05140
uniprot id: E8T295
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

648996:THEAM RS02870
gene id: 648996:THEAM_RS02870
uniprot id: E8T5R1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

648996:THEAM RS03040
gene id: 648996:THEAM_RS03040
uniprot id: E8T5Y6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS05645
gene id: 648996:THEAM_RS05645
uniprot id: E8T2J6
names: Similarity
messages: Belongs to the HupF/HypC family.

648996:THEAM RS06505
gene id: 648996:THEAM_RS06505
uniprot id: E8T3C4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-63 and Arg-66) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

648996:THEAM RS09195
gene id: 648996:THEAM_RS09195
uniprot id: E8T6T7
names: Similarity
messages: Belongs to the GSP E family.

648996:THEAM RS07575
gene id: 648996:THEAM_RS07575
uniprot id: E8T4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

648996:THEAM RS00735
gene id: 648996:THEAM_RS00735
uniprot id: E8T3I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

648996:THEAM RS07420
gene id: 648996:THEAM_RS07420
uniprot id: E8T4A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS00455
gene id: 648996:THEAM_RS00455
uniprot id: E8T359
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

648996:THEAM RS01460
gene id: 648996:THEAM_RS01460
uniprot id: E8T4C4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

648996:THEAM RS01135
gene id: 648996:THEAM_RS01135
uniprot id: E8T3Y4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

648996:THEAM RS04370
gene id: 648996:THEAM_RS04370
uniprot id: E8T6P9
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS06030
gene id: 648996:THEAM_RS06030
uniprot id: E8T2V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

648996:THEAM RS07360
gene id: 648996:THEAM_RS07360
uniprot id: E8T491
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

648996:THEAM RS04805
gene id: 648996:THEAM_RS04805
uniprot id: E8T226
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

648996:THEAM RS05820
gene id: 648996:THEAM_RS05820
uniprot id: E8T2M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

648996:THEAM RS06705
gene id: 648996:THEAM_RS06705
uniprot id: E8T3N6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04885
gene id: 648996:THEAM_RS04885
uniprot id: E8T242
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

648996:THEAM RS05105
gene id: 648996:THEAM_RS05105
uniprot id: E8T288
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

648996:THEAM RS00370
gene id: 648996:THEAM_RS00370
uniprot id: E8T342
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

648996:THEAM RS03260
gene id: 648996:THEAM_RS03260
uniprot id: E8T628
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

648996:THEAM RS05555
gene id: 648996:THEAM_RS05555
uniprot id: E8T2H8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

648996:THEAM RS05040
gene id: 648996:THEAM_RS05040
uniprot id: E8T275
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

648996:THEAM RS05450
gene id: 648996:THEAM_RS05450
uniprot id: E8T2F7
names: Similarity
messages: Belongs to the MotB family.

648996:THEAM RS08460
gene id: 648996:THEAM_RS08460
uniprot id: E8T5G6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS04230
gene id: 648996:THEAM_RS04230
uniprot id: E8T6M1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

648996:THEAM RS01330
gene id: 648996:THEAM_RS01330
uniprot id: E8T423
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

648996:THEAM RS06570
gene id: 648996:THEAM_RS06570
uniprot id: E8T3D6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS03790
gene id: 648996:THEAM_RS03790
uniprot id: E8T6C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

648996:THEAM RS01200
gene id: 648996:THEAM_RS01200
uniprot id: E8T3Z7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

648996:THEAM RS07300
gene id: 648996:THEAM_RS07300
uniprot id: E8T479
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

648996:THEAM RS07320
gene id: 648996:THEAM_RS07320
uniprot id: E8T483
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

648996:THEAM RS07585
gene id: 648996:THEAM_RS07585
uniprot id: E8T4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

648996:THEAM RS00080
gene id: 648996:THEAM_RS00080
uniprot id: E8T2R5
names: Similarity
messages: Belongs to the peptidase C40 family.

648996:THEAM RS01655
gene id: 648996:THEAM_RS01655
uniprot id: E8T4G2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

648996:THEAM RS05915
gene id: 648996:THEAM_RS05915
uniprot id: E8T2P8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

648996:THEAM RS02395
gene id: 648996:THEAM_RS02395
uniprot id: E8T599
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

648996:THEAM RS07080
gene id: 648996:THEAM_RS07080
uniprot id: E8T436
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

648996:THEAM RS06890
gene id: 648996:THEAM_RS06890
uniprot id: E8T3S3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

648996:THEAM RS02260
gene id: 648996:THEAM_RS02260
uniprot id: E8T572
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

648996:THEAM RS04490
gene id: 648996:THEAM_RS04490
uniprot id: E8T1W2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

648996:THEAM RS07555
gene id: 648996:THEAM_RS07555
uniprot id: E8T4K0
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

648996:THEAM RS08415
gene id: 648996:THEAM_RS08415
uniprot id: E8T5F7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04650
gene id: 648996:THEAM_RS04650
uniprot id: E8T1Z4
names: Similarity
messages: Belongs to the HypE family.

648996:THEAM RS06920
gene id: 648996:THEAM_RS06920
uniprot id: E8T3S8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

648996:THEAM RS00665
gene id: 648996:THEAM_RS00665
uniprot id: E8T3H5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

648996:THEAM RS02945
gene id: 648996:THEAM_RS02945
uniprot id: E8T5W8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

648996:THEAM RS00995
gene id: 648996:THEAM_RS00995
uniprot id: E8T3V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

648996:THEAM RS06595
gene id: 648996:THEAM_RS06595
uniprot id: E8T3E1
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS04390
gene id: 648996:THEAM_RS04390
uniprot id: E8T6Q3
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

648996:THEAM RS08015
gene id: 648996:THEAM_RS08015
uniprot id: E8T512
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

648996:THEAM RS03115
gene id: 648996:THEAM_RS03115
uniprot id: E8T601
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

648996:THEAM RS06815
gene id: 648996:THEAM_RS06815
uniprot id: E8T3Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

648996:THEAM RS04825
gene id: 648996:THEAM_RS04825
uniprot id: E8T230
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04365
gene id: 648996:THEAM_RS04365
uniprot id: E8T6P8
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS04290
gene id: 648996:THEAM_RS04290
uniprot id: E8T6N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Interacts with FtsZ.

648996:THEAM RS06005
gene id: 648996:THEAM_RS06005
uniprot id: E8T2U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

648996:THEAM RS01710
gene id: 648996:THEAM_RS01710
uniprot id: E8T4G9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

648996:THEAM RS00040
gene id: 648996:THEAM_RS00040
uniprot id: E8T2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

648996:THEAM RS00340
gene id: 648996:THEAM_RS00340
uniprot id: E8T336
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

648996:THEAM RS01695
gene id: 648996:THEAM_RS01695
uniprot id: E8T4G6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

648996:THEAM RS05795
gene id: 648996:THEAM_RS05795
uniprot id: E8T2M4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

648996:THEAM RS07570
gene id: 648996:THEAM_RS07570
uniprot id: E8T4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

648996:THEAM RS05190
gene id: 648996:THEAM_RS05190
uniprot id: E8T2A5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

648996:THEAM RS07500
gene id: 648996:THEAM_RS07500
uniprot id: E8T4I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

648996:THEAM RS08445
gene id: 648996:THEAM_RS08445
uniprot id: E8T5G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

648996:THEAM RS06335
gene id: 648996:THEAM_RS06335
uniprot id: E8T391
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

648996:THEAM RS08915
gene id: 648996:THEAM_RS08915
uniprot id: E8T6Y3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

648996:THEAM RS02215
gene id: 648996:THEAM_RS02215
uniprot id: E8T563
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

648996:THEAM RS02430
gene id: 648996:THEAM_RS02430
uniprot id: E8T5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

648996:THEAM RS01315
gene id: 648996:THEAM_RS01315
uniprot id: E8T420
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

648996:THEAM RS00005
gene id: 648996:THEAM_RS00005
uniprot id: E8T2Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

648996:THEAM RS01850
gene id: 648996:THEAM_RS01850
uniprot id: E8T4R8
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS06310
gene id: 648996:THEAM_RS06310
uniprot id: E8T386
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

648996:THEAM RS07825
gene id: 648996:THEAM_RS07825
uniprot id: E8T4X7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

648996:THEAM RS03910
gene id: 648996:THEAM_RS03910
uniprot id: E8T6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

648996:THEAM RS05705
gene id: 648996:THEAM_RS05705
uniprot id: E8T2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

648996:THEAM RS02985
gene id: 648996:THEAM_RS02985
uniprot id: E8T5X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

648996:THEAM RS01355
gene id: 648996:THEAM_RS01355
uniprot id: E8T428
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

648996:THEAM RS05610
gene id: 648996:THEAM_RS05610
uniprot id: E8T2I9
names: Similarity
messages: Belongs to the FrhG family.

648996:THEAM RS03420
gene id: 648996:THEAM_RS03420
uniprot id: E8T659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

648996:THEAM RS05935
gene id: 648996:THEAM_RS05935
uniprot id: E8T2T8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

648996:THEAM RS04950
gene id: 648996:THEAM_RS04950
uniprot id: E8T256
names: Similarity
messages: Belongs to the fabD family.

648996:THEAM RS01380
gene id: 648996:THEAM_RS01380
uniprot id: E8T4A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

648996:THEAM RS08980
gene id: 648996:THEAM_RS08980
uniprot id: E8T6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

648996:THEAM RS01925
gene id: 648996:THEAM_RS01925
uniprot id: E8T4T5
names: Similarity
messages: Belongs to the aspartokinase family.

648996:THEAM RS04915
gene id: 648996:THEAM_RS04915
uniprot id: E8T249
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

648996:THEAM RS06500
gene id: 648996:THEAM_RS06500
uniprot id: E8T3C3
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS07405
gene id: 648996:THEAM_RS07405
uniprot id: E8T499
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

648996:THEAM RS07095
gene id: 648996:THEAM_RS07095
uniprot id: E8T439
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

648996:THEAM RS03110
gene id: 648996:THEAM_RS03110
uniprot id: E8T600
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

648996:THEAM RS07275
gene id: 648996:THEAM_RS07275
uniprot id: E8T474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

648996:THEAM RS02435
gene id: 648996:THEAM_RS02435
uniprot id: E8T5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

648996:THEAM RS02270
gene id: 648996:THEAM_RS02270
uniprot id: E8T574
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

648996:THEAM RS01875
gene id: 648996:THEAM_RS01875
uniprot id: E8T4S3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

648996:THEAM RS08600
gene id: 648996:THEAM_RS08600
uniprot id: E8T5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

648996:THEAM RS06985
gene id: 648996:THEAM_RS06985
uniprot id: E8T3U1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

648996:THEAM RS06830
gene id: 648996:THEAM_RS06830
uniprot id: E8T3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

648996:THEAM RS05330
gene id: 648996:THEAM_RS05330
uniprot id: E8T2D4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

648996:THEAM RS06845
gene id: 648996:THEAM_RS06845
uniprot id: E8T3R5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

648996:THEAM RS04180
gene id: 648996:THEAM_RS04180
uniprot id: E8T6L1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04030
gene id: 648996:THEAM_RS04030
uniprot id: E8T6I0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

648996:THEAM RS08435
gene id: 648996:THEAM_RS08435
uniprot id: E8T5G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

648996:THEAM RS01170
gene id: 648996:THEAM_RS01170
uniprot id: E8T3Z1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

648996:THEAM RS05375
gene id: 648996:THEAM_RS05375
uniprot id: E8T2E3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

648996:THEAM RS01560
gene id: 648996:THEAM_RS01560
uniprot id: E8T4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

648996:THEAM RS02500
gene id: 648996:THEAM_RS02500
uniprot id: E8T5C0
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

648996:THEAM RS02265
gene id: 648996:THEAM_RS02265
uniprot id: E8T573
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS03130
gene id: 648996:THEAM_RS03130
uniprot id: E8T604
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS01375
gene id: 648996:THEAM_RS01375
uniprot id: E8T4A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

648996:THEAM RS06155
gene id: 648996:THEAM_RS06155
uniprot id: E8T2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

648996:THEAM RS02045
gene id: 648996:THEAM_RS02045
uniprot id: E8T4V8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

648996:THEAM RS01020
gene id: 648996:THEAM_RS01020
uniprot id: E8T3W1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

648996:THEAM RS04585
gene id: 648996:THEAM_RS04585
uniprot id: E8T1Y1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

648996:THEAM RS01415
gene id: 648996:THEAM_RS01415
uniprot id: E8T4B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

648996:THEAM RS08180
gene id: 648996:THEAM_RS08180
uniprot id: E8T544
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

648996:THEAM RS02620
gene id: 648996:THEAM_RS02620
uniprot id: E8T5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

648996:THEAM RS02565
gene id: 648996:THEAM_RS02565
uniprot id: E8T5J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

648996:THEAM RS00045
gene id: 648996:THEAM_RS00045
uniprot id: E8T2Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

648996:THEAM RS06100
gene id: 648996:THEAM_RS06100
uniprot id: E8T2W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

648996:THEAM RS02475
gene id: 648996:THEAM_RS02475
uniprot id: E8T5B5
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS07970
gene id: 648996:THEAM_RS07970
uniprot id: E8T504
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

648996:THEAM RS03360
gene id: 648996:THEAM_RS03360
uniprot id: E8T647
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS02800
gene id: 648996:THEAM_RS02800
uniprot id: E8T5P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

648996:THEAM RS04875
gene id: 648996:THEAM_RS04875
uniprot id: E8T240
names: Similarity
messages: Belongs to the DtxR/MntR family.

648996:THEAM RS00915
gene id: 648996:THEAM_RS00915
uniprot id: E8T3L9
names: Similarity
messages: Belongs to the DprA/Smf family.

648996:THEAM RS07700
gene id: 648996:THEAM_RS07700
uniprot id: E8T4N0
names: Similarity
messages: Belongs to the OprB family.

648996:THEAM RS02615
gene id: 648996:THEAM_RS02615
uniprot id: E8T5K7
names: Similarity
messages: Belongs to the UPF0166 family.

648996:THEAM RS07445
gene id: 648996:THEAM_RS07445
uniprot id: E8T4H8
names: Similarity
messages: Belongs to the thioredoxin family.

648996:THEAM RS03660
gene id: 648996:THEAM_RS03660
uniprot id: E8T6A3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

648996:THEAM RS07465
gene id: 648996:THEAM_RS07465
uniprot id: E8T4I2
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

648996:THEAM RS06940
gene id: 648996:THEAM_RS06940
uniprot id: E8T3T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

648996:THEAM RS03995
gene id: 648996:THEAM_RS03995
uniprot id: E8T6H3
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

648996:THEAM RS02245
gene id: 648996:THEAM_RS02245
uniprot id: E8T569
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS00440
gene id: 648996:THEAM_RS00440
uniprot id: E8T356
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

648996:THEAM RS02545
gene id: 648996:THEAM_RS02545
uniprot id: E8T5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

648996:THEAM RS03990
gene id: 648996:THEAM_RS03990
uniprot id: E8T6H2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

648996:THEAM RS06290
gene id: 648996:THEAM_RS06290
uniprot id: E8T305
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

648996:THEAM RS04400
gene id: 648996:THEAM_RS04400
uniprot id: E8T6Q5
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

648996:THEAM RS07990
gene id: 648996:THEAM_RS07990
uniprot id: E8T508
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

648996:THEAM RS01365
gene id: 648996:THEAM_RS01365
uniprot id: E8T430
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

648996:THEAM RS01335
gene id: 648996:THEAM_RS01335
uniprot id: E8T424
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

648996:THEAM RS06605
gene id: 648996:THEAM_RS06605
uniprot id: E8T3E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS03140
gene id: 648996:THEAM_RS03140
uniprot id: E8T606
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

648996:THEAM RS04880
gene id: 648996:THEAM_RS04880
uniprot id: E8T241
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

648996:THEAM RS05180
gene id: 648996:THEAM_RS05180
uniprot id: E8T2A3
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

648996:THEAM RS04730
gene id: 648996:THEAM_RS04730
uniprot id: E8T211
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS03190
gene id: 648996:THEAM_RS03190
uniprot id: E8T616
names: Similarity
messages: Belongs to the P(II) protein family.

648996:THEAM RS00840
gene id: 648996:THEAM_RS00840
uniprot id: E8T3K6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS08740
gene id: 648996:THEAM_RS08740
uniprot id: E8T5U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

648996:THEAM RS01280
gene id: 648996:THEAM_RS01280
uniprot id: E8T413
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

648996:THEAM RS07215
gene id: 648996:THEAM_RS07215
uniprot id: E8T463
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

648996:THEAM RS04380
gene id: 648996:THEAM_RS04380
uniprot id: E8T6Q1
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

648996:THEAM RS03305
gene id: 648996:THEAM_RS03305
uniprot id: E8T637
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

648996:THEAM RS06135
gene id: 648996:THEAM_RS06135
uniprot id: E8T2X3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

648996:THEAM RS08780
gene id: 648996:THEAM_RS08780
uniprot id: E8T5V3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

648996:THEAM RS01035
gene id: 648996:THEAM_RS01035
uniprot id: E8T3W4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

648996:THEAM RS06450
gene id: 648996:THEAM_RS06450
uniprot id: E8T3B3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

648996:THEAM RS07410
gene id: 648996:THEAM_RS07410
uniprot id: E8T4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of 2 proteins (FliG, FliN) that might form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

648996:THEAM RS06405
gene id: 648996:THEAM_RS06405
uniprot id: E8T3A4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

648996:THEAM RS01195
gene id: 648996:THEAM_RS01195
uniprot id: E8T3Z6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

648996:THEAM RS07050
gene id: 648996:THEAM_RS07050
uniprot id: E8T3V2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

648996:THEAM RS01810
gene id: 648996:THEAM_RS01810
uniprot id: E8T4R0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS04285
gene id: 648996:THEAM_RS04285
uniprot id: E8T6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

648996:THEAM RS05560
gene id: 648996:THEAM_RS05560
uniprot id: E8T2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

648996:THEAM RS01220
gene id: 648996:THEAM_RS01220
uniprot id: E8T401
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

648996:THEAM RS06045
gene id: 648996:THEAM_RS06045
uniprot id: E8T2V5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

648996:THEAM RS01270
gene id: 648996:THEAM_RS01270
uniprot id: E8T411
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS04925
gene id: 648996:THEAM_RS04925
uniprot id: E8T251
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

648996:THEAM RS03205
gene id: 648996:THEAM_RS03205
uniprot id: E8T618
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

648996:THEAM RS04160
gene id: 648996:THEAM_RS04160
uniprot id: E8T6K7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS00785
gene id: 648996:THEAM_RS00785
uniprot id: E8T3J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS07520
gene id: 648996:THEAM_RS07520
uniprot id: E8T4J3
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS08560
gene id: 648996:THEAM_RS08560
uniprot id: E8T5I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

648996:THEAM RS02370
gene id: 648996:THEAM_RS02370
uniprot id: E8T594
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

648996:THEAM RS05175
gene id: 648996:THEAM_RS05175
uniprot id: E8T2A2
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS03020
gene id: 648996:THEAM_RS03020
uniprot id: E8T5Y2
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS05660
gene id: 648996:THEAM_RS05660
uniprot id: E8T2J9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

648996:THEAM RS02535
gene id: 648996:THEAM_RS02535
uniprot id: E8T5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

648996:THEAM RS02480
gene id: 648996:THEAM_RS02480
uniprot id: E8T5B6
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS02335
gene id: 648996:THEAM_RS02335
uniprot id: E8T587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS00185
gene id: 648996:THEAM_RS00185
uniprot id: E8T307
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

648996:THEAM RS01865
gene id: 648996:THEAM_RS01865
uniprot id: E8T4S1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

648996:THEAM RS01880
gene id: 648996:THEAM_RS01880
uniprot id: E8T4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

648996:THEAM RS00560
gene id: 648996:THEAM_RS00560
uniprot id: E8T380
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

648996:THEAM RS01540
gene id: 648996:THEAM_RS01540
uniprot id: E8T4D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

648996:THEAM RS00540
gene id: 648996:THEAM_RS00540
uniprot id: E8T376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

648996:THEAM RS03185
gene id: 648996:THEAM_RS03185
uniprot id: E8T615
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

648996:THEAM RS07985
gene id: 648996:THEAM_RS07985
uniprot id: E8T507
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

648996:THEAM RS03840
gene id: 648996:THEAM_RS03840
uniprot id: E8T6D9
names: Similarity
messages: Belongs to the peptidase U62 family.

648996:THEAM RS04170
gene id: 648996:THEAM_RS04170
uniprot id: E8T6K9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

648996:THEAM RS05650
gene id: 648996:THEAM_RS05650
uniprot id: E8T2J7
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

648996:THEAM RS00405
gene id: 648996:THEAM_RS00405
uniprot id: E8T349
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS05830
gene id: 648996:THEAM_RS05830
uniprot id: E8T2N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

648996:THEAM RS04565
gene id: 648996:THEAM_RS04565
uniprot id: E8T1X7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

648996:THEAM RS01565
gene id: 648996:THEAM_RS01565
uniprot id: E8T4E4
names: Similarity
messages: Belongs to the RutC family.

648996:THEAM RS02440
gene id: 648996:THEAM_RS02440
uniprot id: E8T5A8
names: Subcellular Location Annotation
messages: Membrane

648996:THEAM RS05790
gene id: 648996:THEAM_RS05790
uniprot id: E8T2M3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

648996:THEAM RS06330
gene id: 648996:THEAM_RS06330
uniprot id: E8T390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

648996:THEAM RS04210
gene id: 648996:THEAM_RS04210
uniprot id: E8T6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

648996:THEAM RS05015
gene id: 648996:THEAM_RS05015
uniprot id: E8T270
names: Similarity
messages: Belongs to the glutamate synthase family.

648996:THEAM RS08020
gene id: 648996:THEAM_RS08020
uniprot id: E8T418
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

648996:THEAM RS03645
gene id: 648996:THEAM_RS03645
uniprot id: E8T6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

648996:THEAM RS07170
gene id: 648996:THEAM_RS07170
uniprot id: E8T454
names: Similarity
messages: Belongs to the universal stress protein A family.

648996:THEAM RS03970
gene id: 648996:THEAM_RS03970
uniprot id: E8T6G8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

648996:THEAM RS09445
gene id: 648996:THEAM_RS09445
uniprot id: E8T6L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

648996:THEAM RS03015
gene id: 648996:THEAM_RS03015
uniprot id: E8T5Y1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

648996:THEAM RS00675
gene id: 648996:THEAM_RS00675
uniprot id: E8T3H7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

648996:THEAM RS08230
gene id: 648996:THEAM_RS08230
uniprot id: E8T5D1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

648996:THEAM RS03290
gene id: 648996:THEAM_RS03290
uniprot id: E8T634
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

648996:THEAM RS08430
gene id: 648996:THEAM_RS08430
uniprot id: E8T5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.