646529:DESACI RS12105
gene id: 646529:DESACI_RS12105
uniprot id: I4D6R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

646529:DESACI RS14505
gene id: 646529:DESACI_RS14505
uniprot id: I4D831
names: Similarity
messages: Belongs to the band 7/mec-2 family.

646529:DESACI RS05000
gene id: 646529:DESACI_RS05000
uniprot id: I4D2Q0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

646529:DESACI RS10140
gene id: 646529:DESACI_RS10140
uniprot id: I4D5M2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS15040
gene id: 646529:DESACI_RS15040
uniprot id: I4D8D7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

646529:DESACI RS18370
gene id: 646529:DESACI_RS18370
uniprot id: I4DAA2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

646529:DESACI RS10520
gene id: 646529:DESACI_RS10520
uniprot id: I4D5V0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS21895
gene id: 646529:DESACI_RS21895
uniprot id: I4DCA7
names: Similarity
messages: Belongs to the peptidase S41A family.

646529:DESACI RS12340
gene id: 646529:DESACI_RS12340
uniprot id: I4D6V4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

646529:DESACI RS14945
gene id: 646529:DESACI_RS14945
uniprot id: I4D8B8
names: Similarity
messages: Belongs to the peptidase C40 family.

646529:DESACI RS02380
gene id: 646529:DESACI_RS02380
uniprot id: I4D179
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

646529:DESACI RS00245
gene id: 646529:DESACI_RS00245
uniprot id: I4D042
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

646529:DESACI RS20515
gene id: 646529:DESACI_RS20515
uniprot id: I4DBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

646529:DESACI RS12795
gene id: 646529:DESACI_RS12795
uniprot id: I4D745
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

646529:DESACI RS05410
gene id: 646529:DESACI_RS05410
uniprot id: I4D2Y1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

646529:DESACI RS16980
gene id: 646529:DESACI_RS16980
uniprot id: I4D9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

646529:DESACI RS17225
gene id: 646529:DESACI_RS17225
uniprot id: I4D9L8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS13845
gene id: 646529:DESACI_RS13845
uniprot id: I4D7P5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

646529:DESACI RS04770
gene id: 646529:DESACI_RS04770
uniprot id: I4D2K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

646529:DESACI RS22000
gene id: 646529:DESACI_RS22000
uniprot id: I4DCC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

646529:DESACI RS21660
gene id: 646529:DESACI_RS21660
uniprot id: I4DC60
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS05230
gene id: 646529:DESACI_RS05230
uniprot id: I4D2U5
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

646529:DESACI RS16815
gene id: 646529:DESACI_RS16815
uniprot id: I4D9D5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS21615
gene id: 646529:DESACI_RS21615
uniprot id: I4DC50
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS19345
gene id: 646529:DESACI_RS19345
uniprot id: I4DAU4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

646529:DESACI RS02850
gene id: 646529:DESACI_RS02850
uniprot id: I4D1H2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS20850
gene id: 646529:DESACI_RS20850
uniprot id: I4DBP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

646529:DESACI RS02445
gene id: 646529:DESACI_RS02445
uniprot id: I4D192
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

646529:DESACI RS04600
gene id: 646529:DESACI_RS04600
uniprot id: I4D2H1
names: Similarity
messages: Belongs to the glutamate synthase family.

646529:DESACI RS22950
gene id: 646529:DESACI_RS22950
uniprot id: I4D1P1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS17975
gene id: 646529:DESACI_RS17975
uniprot id: I4DA20
names: Similarity
messages: Belongs to the transpeptidase family.

646529:DESACI RS02265
gene id: 646529:DESACI_RS02265
uniprot id: I4D157
names: Similarity
messages: Belongs to the ycf81 family.

646529:DESACI RS03565
gene id: 646529:DESACI_RS03565
uniprot id: I4D1W7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

646529:DESACI RS00095
gene id: 646529:DESACI_RS00095
uniprot id: I4D012
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

646529:DESACI RS08045
gene id: 646529:DESACI_RS08045
uniprot id: I4D4G0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS14700
gene id: 646529:DESACI_RS14700
uniprot id: I4D872
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm

646529:DESACI RS09030
gene id: 646529:DESACI_RS09030
uniprot id: I4D4Z9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

646529:DESACI RS11290
gene id: 646529:DESACI_RS11290
uniprot id: I4D6A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

646529:DESACI RS03085
gene id: 646529:DESACI_RS03085
uniprot id: I4D1M2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

646529:DESACI RS21460
gene id: 646529:DESACI_RS21460
uniprot id: I4DC16
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS05050
gene id: 646529:DESACI_RS05050
uniprot id: I4D2Q9
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

646529:DESACI RS15280
gene id: 646529:DESACI_RS15280
uniprot id: I4D8I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

646529:DESACI RS04975
gene id: 646529:DESACI_RS04975
uniprot id: I4D2P5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS09755
gene id: 646529:DESACI_RS09755
uniprot id: I4D5E6
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

646529:DESACI RS17915
gene id: 646529:DESACI_RS17915
uniprot id: I4DA08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

646529:DESACI RS09115
gene id: 646529:DESACI_RS09115
uniprot id: I4D516
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

646529:DESACI RS03640
gene id: 646529:DESACI_RS03640
uniprot id: I4D1Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

646529:DESACI RS19180
gene id: 646529:DESACI_RS19180
uniprot id: I4DAR2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

646529:DESACI RS15505
gene id: 646529:DESACI_RS15505
uniprot id: I4D8M9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

646529:DESACI RS10155
gene id: 646529:DESACI_RS10155
uniprot id: I4D5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS03785
gene id: 646529:DESACI_RS03785
uniprot id: I4D212
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

646529:DESACI RS00655
gene id: 646529:DESACI_RS00655
uniprot id: I4D092
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

646529:DESACI RS13000
gene id: 646529:DESACI_RS13000
uniprot id: I4D787
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS17960
gene id: 646529:DESACI_RS17960
uniprot id: I4DA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

646529:DESACI RS05555
gene id: 646529:DESACI_RS05555
uniprot id: I4D310
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

646529:DESACI RS03820
gene id: 646529:DESACI_RS03820
uniprot id: I4D218
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

646529:DESACI RS01990
gene id: 646529:DESACI_RS01990
uniprot id: I4D100
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

646529:DESACI RS16525
gene id: 646529:DESACI_RS16525
uniprot id: I4D980
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS02360
gene id: 646529:DESACI_RS02360
uniprot id: I4D175
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

646529:DESACI RS05570
gene id: 646529:DESACI_RS05570
uniprot id: I4D313
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

646529:DESACI RS14605
gene id: 646529:DESACI_RS14605
uniprot id: I4D853
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

646529:DESACI RS19800
gene id: 646529:DESACI_RS19800
uniprot id: I4DB42
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

646529:DESACI RS09280
gene id: 646529:DESACI_RS09280
uniprot id: I4D551
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

646529:DESACI RS03455
gene id: 646529:DESACI_RS03455
uniprot id: I4D1U5
names: Similarity
messages: Belongs to the YggT family.

646529:DESACI RS14690
gene id: 646529:DESACI_RS14690
uniprot id: I4D870
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS16855
gene id: 646529:DESACI_RS16855
uniprot id: I4D9E3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

646529:DESACI RS12530
gene id: 646529:DESACI_RS12530
uniprot id: I4D6Z1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

646529:DESACI RS22395
gene id: 646529:DESACI_RS22395
uniprot id: I4DCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

646529:DESACI RS16280
gene id: 646529:DESACI_RS16280
uniprot id: I4D933
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS19615
gene id: 646529:DESACI_RS19615
uniprot id: I4DB00
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

646529:DESACI RS17640
gene id: 646529:DESACI_RS17640
uniprot id: I4D9V2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS13800
gene id: 646529:DESACI_RS13800
uniprot id: I4D7N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

646529:DESACI RS22375
gene id: 646529:DESACI_RS22375
uniprot id: I4DCJ9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

646529:DESACI RS20990
gene id: 646529:DESACI_RS20990
uniprot id: I4DBS3
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS21560
gene id: 646529:DESACI_RS21560
uniprot id: I4DC37
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08520
gene id: 646529:DESACI_RS08520
uniprot id: I4D4Q3
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS12550
gene id: 646529:DESACI_RS12550
uniprot id: I4D6Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

646529:DESACI RS11120
gene id: 646529:DESACI_RS11120
uniprot id: I4D667
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS03230
gene id: 646529:DESACI_RS03230
uniprot id: I4D1Q0
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS02510
gene id: 646529:DESACI_RS02510
uniprot id: I4D1A6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

646529:DESACI RS20195
gene id: 646529:DESACI_RS20195
uniprot id: I4DBC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

646529:DESACI RS11495
gene id: 646529:DESACI_RS11495
uniprot id: I4D6E5
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

646529:DESACI RS21975
gene id: 646529:DESACI_RS21975
uniprot id: I4DCC1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

646529:DESACI RS08675
gene id: 646529:DESACI_RS08675
uniprot id: I4D4T5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS11980
gene id: 646529:DESACI_RS11980
uniprot id: I4D6N6
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

646529:DESACI RS04130
gene id: 646529:DESACI_RS04130
uniprot id: I4D279
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

646529:DESACI RS02825
gene id: 646529:DESACI_RS02825
uniprot id: I4D1G6
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS16405
gene id: 646529:DESACI_RS16405
uniprot id: I4D956
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS15380
gene id: 646529:DESACI_RS15380
uniprot id: I4D8K7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

646529:DESACI RS13130
gene id: 646529:DESACI_RS13130
uniprot id: I4D7B0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS02355
gene id: 646529:DESACI_RS02355
uniprot id: I4D174
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

646529:DESACI RS21780
gene id: 646529:DESACI_RS21780
uniprot id: I4DC84
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

646529:DESACI RS20655
gene id: 646529:DESACI_RS20655
uniprot id: I4DBL0
names: Similarity
messages: Belongs to the peptidase S16 family.

646529:DESACI RS09225
gene id: 646529:DESACI_RS09225
uniprot id: I4D539
names: Similarity
messages: Belongs to the Ahb/Nir family.

646529:DESACI RS07220
gene id: 646529:DESACI_RS07220
uniprot id: I4D3Z9
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

646529:DESACI RS20505
gene id: 646529:DESACI_RS20505
uniprot id: I4DBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

646529:DESACI RS23045
gene id: 646529:DESACI_RS23045
uniprot id: I4D4G5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS20440
gene id: 646529:DESACI_RS20440
uniprot id: I4DBG9
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13325
gene id: 646529:DESACI_RS13325
uniprot id: I4D7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

646529:DESACI RS18605
gene id: 646529:DESACI_RS18605
uniprot id: I4DAE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS05765
gene id: 646529:DESACI_RS05765
uniprot id: I4D349
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS00420
gene id: 646529:DESACI_RS00420
uniprot id: I4D080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

646529:DESACI RS13005
gene id: 646529:DESACI_RS13005
uniprot id: I4D788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

646529:DESACI RS15730
gene id: 646529:DESACI_RS15730
uniprot id: I4D8S3
names: Similarity
messages: Belongs to the GerABKA family.

646529:DESACI RS01650
gene id: 646529:DESACI_RS01650
uniprot id: I4D0T4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS15835
gene id: 646529:DESACI_RS15835
uniprot id: I4D8U4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

646529:DESACI RS17720
gene id: 646529:DESACI_RS17720
uniprot id: I4D9W9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS07190
gene id: 646529:DESACI_RS07190
uniprot id: I4D3Z3
names: Similarity
messages: Belongs to the PRORSD1 family.

646529:DESACI RS22120
gene id: 646529:DESACI_RS22120
uniprot id: I4DCF0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

646529:DESACI RS17630
gene id: 646529:DESACI_RS17630
uniprot id: I4D9V0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

646529:DESACI RS15360
gene id: 646529:DESACI_RS15360
uniprot id: I4D8K3
names: Similarity
messages: Belongs to the UPF0234 family.

646529:DESACI RS17715
gene id: 646529:DESACI_RS17715
uniprot id: I4D9W8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS14075
gene id: 646529:DESACI_RS14075
uniprot id: I4D7U4
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS15355
gene id: 646529:DESACI_RS15355
uniprot id: I4D8K2
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

646529:DESACI RS00710
gene id: 646529:DESACI_RS00710
uniprot id: I4D0A4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

646529:DESACI RS08730
gene id: 646529:DESACI_RS08730
uniprot id: I4D4U6
names: Similarity
messages: Belongs to the UPF0735 family.

646529:DESACI RS21425
gene id: 646529:DESACI_RS21425
uniprot id: I4DC09
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS16395
gene id: 646529:DESACI_RS16395
uniprot id: I4D954
names: Similarity
messages: Belongs to the GSP E family.

646529:DESACI RS19265
gene id: 646529:DESACI_RS19265
uniprot id: I4DAS9
names: Similarity
messages: Belongs to the P(II) protein family.

646529:DESACI RS08465
gene id: 646529:DESACI_RS08465
uniprot id: I4D4P2
names: Similarity
messages: Belongs to the peptidase C40 family.

646529:DESACI RS20665
gene id: 646529:DESACI_RS20665
uniprot id: I4DBL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

646529:DESACI RS14035
gene id: 646529:DESACI_RS14035
uniprot id: I4D7T6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

646529:DESACI RS14195
gene id: 646529:DESACI_RS14195
uniprot id: I4D7W7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

646529:DESACI RS02090
gene id: 646529:DESACI_RS02090
uniprot id: I4D120
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS17515
gene id: 646529:DESACI_RS17515
uniprot id: I4D9S7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

646529:DESACI RS05445
gene id: 646529:DESACI_RS05445
uniprot id: I4D2Y8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

646529:DESACI RS15930
gene id: 646529:DESACI_RS15930
uniprot id: I4D8W3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

646529:DESACI RS16780
gene id: 646529:DESACI_RS16780
uniprot id: I4D9C9
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS14835
gene id: 646529:DESACI_RS14835
uniprot id: I4D896
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS17675
gene id: 646529:DESACI_RS17675
uniprot id: I4D9V9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

646529:DESACI RS11140
gene id: 646529:DESACI_RS11140
uniprot id: I4D671
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS00035
gene id: 646529:DESACI_RS00035
uniprot id: I4D005
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

646529:DESACI RS18360
gene id: 646529:DESACI_RS18360
uniprot id: I4DAA0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

646529:DESACI RS18545
gene id: 646529:DESACI_RS18545
uniprot id: I4DAD8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS16260
gene id: 646529:DESACI_RS16260
uniprot id: I4D929
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

646529:DESACI RS22400
gene id: 646529:DESACI_RS22400
uniprot id: I4DCK4
names: Similarity
messages: Belongs to the peptidase M18 family.

646529:DESACI RS19255
gene id: 646529:DESACI_RS19255
uniprot id: I4DAS7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

646529:DESACI RS02435
gene id: 646529:DESACI_RS02435
uniprot id: I4D190
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

646529:DESACI RS08430
gene id: 646529:DESACI_RS08430
uniprot id: I4D4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

646529:DESACI RS13755
gene id: 646529:DESACI_RS13755
uniprot id: I4D7M8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

646529:DESACI RS07205
gene id: 646529:DESACI_RS07205
uniprot id: I4D3Z6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

646529:DESACI RS16100
gene id: 646529:DESACI_RS16100
uniprot id: I4D8Z6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS16645
gene id: 646529:DESACI_RS16645
uniprot id: I4D9A6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

646529:DESACI RS21875
gene id: 646529:DESACI_RS21875
uniprot id: I4DCA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

646529:DESACI RS02985
gene id: 646529:DESACI_RS02985
uniprot id: I4D1K2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

646529:DESACI RS21295
gene id: 646529:DESACI_RS21295
uniprot id: I4DBY5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS17650
gene id: 646529:DESACI_RS17650
uniprot id: I4D9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

646529:DESACI RS17295
gene id: 646529:DESACI_RS17295
uniprot id: I4D9N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

646529:DESACI RS04345
gene id: 646529:DESACI_RS04345
uniprot id: I4D2B9
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08030
gene id: 646529:DESACI_RS08030
uniprot id: I4D4F7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

646529:DESACI RS16740
gene id: 646529:DESACI_RS16740
uniprot id: I4D9C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS04375
gene id: 646529:DESACI_RS04375
uniprot id: I4D2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

646529:DESACI RS18220
gene id: 646529:DESACI_RS18220
uniprot id: U3GKJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

646529:DESACI RS15005
gene id: 646529:DESACI_RS15005
uniprot id: I4D8D0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

646529:DESACI RS01315
gene id: 646529:DESACI_RS01315
uniprot id: I4D0L5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

646529:DESACI RS13610
gene id: 646529:DESACI_RS13610
uniprot id: I4D7J9
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08650
gene id: 646529:DESACI_RS08650
uniprot id: I4D4T0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

646529:DESACI RS18160
gene id: 646529:DESACI_RS18160
uniprot id: I4DA59
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

646529:DESACI RS10960
gene id: 646529:DESACI_RS10960
uniprot id: I4D635
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

646529:DESACI RS05240
gene id: 646529:DESACI_RS05240
uniprot id: I4D2U7
names: Similarity
messages: Belongs to the Nth/MutY family.

646529:DESACI RS10305
gene id: 646529:DESACI_RS10305
uniprot id: I4D5Q5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS14725
gene id: 646529:DESACI_RS14725
uniprot id: I4D877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS00740
gene id: 646529:DESACI_RS00740
uniprot id: I4D0B0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

646529:DESACI RS16915
gene id: 646529:DESACI_RS16915
uniprot id: I4D9F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

646529:DESACI RS11420
gene id: 646529:DESACI_RS11420
uniprot id: I4D6C7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS01130
gene id: 646529:DESACI_RS01130
uniprot id: I4D0H9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

646529:DESACI RS17965
gene id: 646529:DESACI_RS17965
uniprot id: I4DA18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

646529:DESACI RS02645
gene id: 646529:DESACI_RS02645
uniprot id: I4D1D3
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

646529:DESACI RS04110
gene id: 646529:DESACI_RS04110
uniprot id: I4D274
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS13255
gene id: 646529:DESACI_RS13255
uniprot id: I4D7D7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

646529:DESACI RS12680
gene id: 646529:DESACI_RS12680
uniprot id: I4D722
names: Similarity
messages: Belongs to the UPF0166 family.

646529:DESACI RS13860
gene id: 646529:DESACI_RS13860
uniprot id: I4D7P8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

646529:DESACI RS18065
gene id: 646529:DESACI_RS18065
uniprot id: I4DA40
names: Similarity
messages: Belongs to the peptidase U62 family.

646529:DESACI RS14950
gene id: 646529:DESACI_RS14950
uniprot id: I4D8B9
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

646529:DESACI RS17180
gene id: 646529:DESACI_RS17180
uniprot id: I4D9K9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS18295
gene id: 646529:DESACI_RS18295
uniprot id: I4DA86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

646529:DESACI RS02345
gene id: 646529:DESACI_RS02345
uniprot id: I4D172
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

646529:DESACI RS02625
gene id: 646529:DESACI_RS02625
uniprot id: I4D1C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

646529:DESACI RS05470
gene id: 646529:DESACI_RS05470
uniprot id: I4D2Z3
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

646529:DESACI RS12555
gene id: 646529:DESACI_RS12555
uniprot id: I4D6Z6
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS08710
gene id: 646529:DESACI_RS08710
uniprot id: I4D4U2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

646529:DESACI RS15285
gene id: 646529:DESACI_RS15285
uniprot id: I4D8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

646529:DESACI RS15490
gene id: 646529:DESACI_RS15490
uniprot id: I4D8M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

646529:DESACI RS09750
gene id: 646529:DESACI_RS09750
uniprot id: I4D5E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

646529:DESACI RS07715
gene id: 646529:DESACI_RS07715
uniprot id: I4D493
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS05805
gene id: 646529:DESACI_RS05805
uniprot id: I4D357
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

646529:DESACI RS18265
gene id: 646529:DESACI_RS18265
uniprot id: I4DA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS03335
gene id: 646529:DESACI_RS03335
uniprot id: I4D1S2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

646529:DESACI RS01585
gene id: 646529:DESACI_RS01585
uniprot id: I4D0S1
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS20755
gene id: 646529:DESACI_RS20755
uniprot id: I4DBM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

646529:DESACI RS16005
gene id: 646529:DESACI_RS16005
uniprot id: I4D8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

646529:DESACI RS22050
gene id: 646529:DESACI_RS22050
uniprot id: I4DCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

646529:DESACI RS07595
gene id: 646529:DESACI_RS07595
uniprot id: I4D468
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS07285
gene id: 646529:DESACI_RS07285
uniprot id: I4D411
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08415
gene id: 646529:DESACI_RS08415
uniprot id: I4D4N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

646529:DESACI RS07735
gene id: 646529:DESACI_RS07735
uniprot id: I4D497
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS15510
gene id: 646529:DESACI_RS15510
uniprot id: I4D8N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

646529:DESACI RS22430
gene id: 646529:DESACI_RS22430
uniprot id: I4DCL0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS20430
gene id: 646529:DESACI_RS20430
uniprot id: I4DBG7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

646529:DESACI RS08670
gene id: 646529:DESACI_RS08670
uniprot id: I4D4T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

646529:DESACI RS16800
gene id: 646529:DESACI_RS16800
uniprot id: I4D9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

646529:DESACI RS05280
gene id: 646529:DESACI_RS05280
uniprot id: I4D2V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

646529:DESACI RS18055
gene id: 646529:DESACI_RS18055
uniprot id: I4DA38
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

646529:DESACI RS08970
gene id: 646529:DESACI_RS08970
uniprot id: I4D4Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

646529:DESACI RS04180
gene id: 646529:DESACI_RS04180
uniprot id: I4D289
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

646529:DESACI RS00130
gene id: 646529:DESACI_RS00130
uniprot id: I4D019
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

646529:DESACI RS13545
gene id: 646529:DESACI_RS13545
uniprot id: I4D7I6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS10625
gene id: 646529:DESACI_RS10625
uniprot id: I4D5X0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

646529:DESACI RS11245
gene id: 646529:DESACI_RS11245
uniprot id: I4D692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

646529:DESACI RS17445
gene id: 646529:DESACI_RS17445
uniprot id: I4D9R3
names: Similarity
messages: Belongs to the fabD family.

646529:DESACI RS00110
gene id: 646529:DESACI_RS00110
uniprot id: I4D015
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

646529:DESACI RS10450
gene id: 646529:DESACI_RS10450
uniprot id: I4D5T5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

646529:DESACI RS21405
gene id: 646529:DESACI_RS21405
uniprot id: I4DC07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS11690
gene id: 646529:DESACI_RS11690
uniprot id: I4D6I1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

646529:DESACI RS17905
gene id: 646529:DESACI_RS17905
uniprot id: I4DA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

646529:DESACI RS00365
gene id: 646529:DESACI_RS00365
uniprot id: I4D069
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

646529:DESACI RS03980
gene id: 646529:DESACI_RS03980
uniprot id: I4D247
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
messages: Homotetramer.

646529:DESACI RS13815
gene id: 646529:DESACI_RS13815
uniprot id: I4D7N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

646529:DESACI RS01035
gene id: 646529:DESACI_RS01035
uniprot id: I4D0G0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS19250
gene id: 646529:DESACI_RS19250
uniprot id: I4DAS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

646529:DESACI RS04405
gene id: 646529:DESACI_RS04405
uniprot id: I4D2D1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS20575
gene id: 646529:DESACI_RS20575
uniprot id: I4DBJ5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

646529:DESACI RS14485
gene id: 646529:DESACI_RS14485
uniprot id: I4D827
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

646529:DESACI RS08480
gene id: 646529:DESACI_RS08480
uniprot id: I4D4P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS09845
gene id: 646529:DESACI_RS09845
uniprot id: I4D5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

646529:DESACI RS06085
gene id: 646529:DESACI_RS06085
uniprot id: I4D3B2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS22580
gene id: 646529:DESACI_RS22580
uniprot id: I4DCN8
names: Similarity
messages: Belongs to the peptidase A24 family.

646529:DESACI RS13060
gene id: 646529:DESACI_RS13060
uniprot id: I4D799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

646529:DESACI RS20100
gene id: 646529:DESACI_RS20100
uniprot id: I4DBA0
names: Similarity
messages: Belongs to the UPF0045 family.

646529:DESACI RS05755
gene id: 646529:DESACI_RS05755
uniprot id: I4D347
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS13895
gene id: 646529:DESACI_RS13895
uniprot id: I4D7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

646529:DESACI RS02250
gene id: 646529:DESACI_RS02250
uniprot id: I4D154
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

646529:DESACI RS24045
gene id: 646529:DESACI_RS24045
uniprot id: I4DBG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

646529:DESACI RS18880
gene id: 646529:DESACI_RS18880
uniprot id: I4DAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

646529:DESACI RS22345
gene id: 646529:DESACI_RS22345
uniprot id: I4DCJ3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

646529:DESACI RS07810
gene id: 646529:DESACI_RS07810
uniprot id: I4D4B1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS19785
gene id: 646529:DESACI_RS19785
uniprot id: I4DB39
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

646529:DESACI RS08110
gene id: 646529:DESACI_RS08110
uniprot id: I4D4H2
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS17455
gene id: 646529:DESACI_RS17455
uniprot id: I4D9R5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

646529:DESACI RS05615
gene id: 646529:DESACI_RS05615
uniprot id: I4D321
names: Similarity
messages: Belongs to the terpene synthase family.

646529:DESACI RS00240
gene id: 646529:DESACI_RS00240
uniprot id: I4D041
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

646529:DESACI RS16435
gene id: 646529:DESACI_RS16435
uniprot id: I4D961
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

646529:DESACI RS14425
gene id: 646529:DESACI_RS14425
uniprot id: I4D814
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

646529:DESACI RS17700
gene id: 646529:DESACI_RS17700
uniprot id: I4D9W4
names: Similarity
messages: Belongs to the transpeptidase family.

646529:DESACI RS00410
gene id: 646529:DESACI_RS00410
uniprot id: I4D078
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

646529:DESACI RS15305
gene id: 646529:DESACI_RS15305
uniprot id: I4D8J2
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

646529:DESACI RS10510
gene id: 646529:DESACI_RS10510
uniprot id: I4D5U8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

646529:DESACI RS09120
gene id: 646529:DESACI_RS09120
uniprot id: I4D517
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

646529:DESACI RS14655
gene id: 646529:DESACI_RS14655
uniprot id: I4D863
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

646529:DESACI RS14580
gene id: 646529:DESACI_RS14580
uniprot id: I4D848
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

646529:DESACI RS04620
gene id: 646529:DESACI_RS04620
uniprot id: I4D2H5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

646529:DESACI RS17345
gene id: 646529:DESACI_RS17345
uniprot id: I4D9P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS02200
gene id: 646529:DESACI_RS02200
uniprot id: I4D144
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS00010
gene id: 646529:DESACI_RS00010
uniprot id: I4D000
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

646529:DESACI RS09210
gene id: 646529:DESACI_RS09210
uniprot id: I4D535
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

646529:DESACI RS13830
gene id: 646529:DESACI_RS13830
uniprot id: I4D7P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

646529:DESACI RS03280
gene id: 646529:DESACI_RS03280
uniprot id: I4D1R1
names: Subcellular Location Annotation
messages: Cytoplasm

646529:DESACI RS20545
gene id: 646529:DESACI_RS20545
uniprot id: I4DBJ0
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

646529:DESACI RS17740
gene id: 646529:DESACI_RS17740
uniprot id: I4D9X3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS02640
gene id: 646529:DESACI_RS02640
uniprot id: I4D1D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

646529:DESACI RS17525
gene id: 646529:DESACI_RS17525
uniprot id: I4D9S9
names: Similarity
messages: Belongs to the asp23 family.

646529:DESACI RS14955
gene id: 646529:DESACI_RS14955
uniprot id: I4D8C0
names: Similarity
messages: Belongs to the UPF0237 family.

646529:DESACI RS06550
gene id: 646529:DESACI_RS06550
uniprot id: I4D3L8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS01475
gene id: 646529:DESACI_RS01475
uniprot id: I4D0P6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

646529:DESACI RS18415
gene id: 646529:DESACI_RS18415
uniprot id: I4DAB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

646529:DESACI RS01525
gene id: 646529:DESACI_RS01525
uniprot id: I4D0Q7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS22175
gene id: 646529:DESACI_RS22175
uniprot id: I4DCG1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS22605
gene id: 646529:DESACI_RS22605
uniprot id: I4DCP3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

646529:DESACI RS05295
gene id: 646529:DESACI_RS05295
uniprot id: I4D2V8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

646529:DESACI RS17325
gene id: 646529:DESACI_RS17325
uniprot id: I4D9N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

646529:DESACI RS17535
gene id: 646529:DESACI_RS17535
uniprot id: I4D9T1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

646529:DESACI RS13535
gene id: 646529:DESACI_RS13535
uniprot id: I4D7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

646529:DESACI RS07175
gene id: 646529:DESACI_RS07175
uniprot id: I4D3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS18735
gene id: 646529:DESACI_RS18735
uniprot id: I4DAH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

646529:DESACI RS11565
gene id: 646529:DESACI_RS11565
uniprot id: I4D6F7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS14185
gene id: 646529:DESACI_RS14185
uniprot id: I4D7W5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

646529:DESACI RS02870
gene id: 646529:DESACI_RS02870
uniprot id: I4D1H6
names: Similarity
messages: Belongs to the P(II) protein family.

646529:DESACI RS18940
gene id: 646529:DESACI_RS18940
uniprot id: I4DAL3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

646529:DESACI RS17950
gene id: 646529:DESACI_RS17950
uniprot id: I4DA15
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08180
gene id: 646529:DESACI_RS08180
uniprot id: I4D4I6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

646529:DESACI RS13035
gene id: 646529:DESACI_RS13035
uniprot id: I4D794
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

646529:DESACI RS12945
gene id: 646529:DESACI_RS12945
uniprot id: I4D775
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS03430
gene id: 646529:DESACI_RS03430
uniprot id: I4D1U0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS15020
gene id: 646529:DESACI_RS15020
uniprot id: I4D8D3
names: Similarity
messages: Belongs to the threonine synthase family.

646529:DESACI RS18240
gene id: 646529:DESACI_RS18240
uniprot id: I4DA75
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS08100
gene id: 646529:DESACI_RS08100
uniprot id: I4D4H0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS20600
gene id: 646529:DESACI_RS20600
uniprot id: I4DBK0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

646529:DESACI RS18110
gene id: 646529:DESACI_RS18110
uniprot id: I4DA49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

646529:DESACI RS22010
gene id: 646529:DESACI_RS22010
uniprot id: I4DCC8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

646529:DESACI RS16605
gene id: 646529:DESACI_RS16605
uniprot id: I4D998
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

646529:DESACI RS19650
gene id: 646529:DESACI_RS19650
uniprot id: I4DB07
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

646529:DESACI RS00855
gene id: 646529:DESACI_RS00855
uniprot id: I4D0C6
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

646529:DESACI RS12570
gene id: 646529:DESACI_RS12570
uniprot id: I4D6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS17755
gene id: 646529:DESACI_RS17755
uniprot id: I4D9X6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

646529:DESACI RS24945
gene id: 646529:DESACI_RS24945
uniprot id: I4DBG6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

646529:DESACI RS03410
gene id: 646529:DESACI_RS03410
uniprot id: I4D1T6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS02395
gene id: 646529:DESACI_RS02395
uniprot id: I4D182
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

646529:DESACI RS02530
gene id: 646529:DESACI_RS02530
uniprot id: I4D1B0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

646529:DESACI RS17545
gene id: 646529:DESACI_RS17545
uniprot id: I4D9T3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

646529:DESACI RS05075
gene id: 646529:DESACI_RS05075
uniprot id: I4D2R4
names: Similarity
messages: Belongs to the ribulokinase family.

646529:DESACI RS15345
gene id: 646529:DESACI_RS15345
uniprot id: I4D8K0
names: Similarity
messages: Belongs to the PstS family.

646529:DESACI RS21305
gene id: 646529:DESACI_RS21305
uniprot id: I4DBY7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

646529:DESACI RS20735
gene id: 646529:DESACI_RS20735
uniprot id: I4DBM6
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS07510
gene id: 646529:DESACI_RS07510
uniprot id: I4D451
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

646529:DESACI RS18215
gene id: 646529:DESACI_RS18215
uniprot id: U3GJK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

646529:DESACI RS20040
gene id: 646529:DESACI_RS20040
uniprot id: I4DB88
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS16450
gene id: 646529:DESACI_RS16450
uniprot id: I4D964
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

646529:DESACI RS20410
gene id: 646529:DESACI_RS20410
uniprot id: I4DBG3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

646529:DESACI RS21160
gene id: 646529:DESACI_RS21160
uniprot id: I4DBV7
names: Similarity
messages: Belongs to the FemABX family.

646529:DESACI RS08540
gene id: 646529:DESACI_RS08540
uniprot id: I4D4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

646529:DESACI RS16085
gene id: 646529:DESACI_RS16085
uniprot id: I4D8Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

646529:DESACI RS00735
gene id: 646529:DESACI_RS00735
uniprot id: I4D0A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

646529:DESACI RS22145
gene id: 646529:DESACI_RS22145
uniprot id: I4DCF5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

646529:DESACI RS17240
gene id: 646529:DESACI_RS17240
uniprot id: I4D9M1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

646529:DESACI RS15055
gene id: 646529:DESACI_RS15055
uniprot id: I4D8E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS05035
gene id: 646529:DESACI_RS05035
uniprot id: I4D2Q6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

646529:DESACI RS00385
gene id: 646529:DESACI_RS00385
uniprot id: I4D073
names: Similarity
messages: Belongs to the DHPS family.

646529:DESACI RS18615
gene id: 646529:DESACI_RS18615
uniprot id: I4DAF1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS07615
gene id: 646529:DESACI_RS07615
uniprot id: I4D472
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

646529:DESACI RS17195
gene id: 646529:DESACI_RS17195
uniprot id: I4D9L2
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS17230
gene id: 646529:DESACI_RS17230
uniprot id: I4D9L9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS11095
gene id: 646529:DESACI_RS11095
uniprot id: I4D662
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

646529:DESACI RS04530
gene id: 646529:DESACI_RS04530
uniprot id: I4D2F7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

646529:DESACI RS19995
gene id: 646529:DESACI_RS19995
uniprot id: I4DB79
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS19980
gene id: 646529:DESACI_RS19980
uniprot id: I4DB77
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS22130
gene id: 646529:DESACI_RS22130
uniprot id: I4DCF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

646529:DESACI RS16920
gene id: 646529:DESACI_RS16920
uniprot id: I4D9F6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS22670
gene id: 646529:DESACI_RS22670
uniprot id: I4DCQ8
names: Similarity
messages: Belongs to the PemK/MazF family.

646529:DESACI RS14335
gene id: 646529:DESACI_RS14335
uniprot id: I4D7Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

646529:DESACI RS14290
gene id: 646529:DESACI_RS14290
uniprot id: I4D7Y7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

646529:DESACI RS06535
gene id: 646529:DESACI_RS06535
uniprot id: I4D3L4
names: Similarity
messages: Belongs to the PspA/IM30 family.

646529:DESACI RS17290
gene id: 646529:DESACI_RS17290
uniprot id: I4D9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

646529:DESACI RS11265
gene id: 646529:DESACI_RS11265
uniprot id: I4D696
names: Similarity
messages: Belongs to the ThiD family.

646529:DESACI RS15775
gene id: 646529:DESACI_RS15775
uniprot id: I4D8T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

646529:DESACI RS21340
gene id: 646529:DESACI_RS21340
uniprot id: I4DBZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

646529:DESACI RS18165
gene id: 646529:DESACI_RS18165
uniprot id: I4DA60
names: Similarity
messages: Belongs to the FlgD family.

646529:DESACI RS01615
gene id: 646529:DESACI_RS01615
uniprot id: I4D0S7
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS16940
gene id: 646529:DESACI_RS16940
uniprot id: I4D9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

646529:DESACI RS02745
gene id: 646529:DESACI_RS02745
uniprot id: I4D1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS02325
gene id: 646529:DESACI_RS02325
uniprot id: I4D168
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

646529:DESACI RS04665
gene id: 646529:DESACI_RS04665
uniprot id: I4D2I5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS21910
gene id: 646529:DESACI_RS21910
uniprot id: I4DCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

646529:DESACI RS16950
gene id: 646529:DESACI_RS16950
uniprot id: I4D9G2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

646529:DESACI RS17415
gene id: 646529:DESACI_RS17415
uniprot id: I4D9Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

646529:DESACI RS04225
gene id: 646529:DESACI_RS04225
uniprot id: I4D2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

646529:DESACI RS08440
gene id: 646529:DESACI_RS08440
uniprot id: I4D4N7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS02605
gene id: 646529:DESACI_RS02605
uniprot id: I4D1C5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS04650
gene id: 646529:DESACI_RS04650
uniprot id: I4D2I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

646529:DESACI RS10815
gene id: 646529:DESACI_RS10815
uniprot id: I4D605
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS00860
gene id: 646529:DESACI_RS00860
uniprot id: I4D0C7
names: Similarity
messages: Belongs to the GerABKA family.

646529:DESACI RS11085
gene id: 646529:DESACI_RS11085
uniprot id: I4D659
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS02665
gene id: 646529:DESACI_RS02665
uniprot id: I4D1D7
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

646529:DESACI RS04365
gene id: 646529:DESACI_RS04365
uniprot id: I4D2C3
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS17510
gene id: 646529:DESACI_RS17510
uniprot id: I4D9S6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

646529:DESACI RS21400
gene id: 646529:DESACI_RS21400
uniprot id: I4DC06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS08715
gene id: 646529:DESACI_RS08715
uniprot id: I4D4U3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS18480
gene id: 646529:DESACI_RS18480
uniprot id: I4DAC6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

646529:DESACI RS06055
gene id: 646529:DESACI_RS06055
uniprot id: I4D3A6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

646529:DESACI RS05610
gene id: 646529:DESACI_RS05610
uniprot id: I4D320
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

646529:DESACI RS16870
gene id: 646529:DESACI_RS16870
uniprot id: I4D9E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

646529:DESACI RS03145
gene id: 646529:DESACI_RS03145
uniprot id: I4D1N4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS09790
gene id: 646529:DESACI_RS09790
uniprot id: I4D5F3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

646529:DESACI RS02330
gene id: 646529:DESACI_RS02330
uniprot id: I4D169
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

646529:DESACI RS16475
gene id: 646529:DESACI_RS16475
uniprot id: I4D970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

646529:DESACI RS09530
gene id: 646529:DESACI_RS09530
uniprot id: I4D597
names: Similarity
messages: Belongs to the OsmC/Ohr family.

646529:DESACI RS04140
gene id: 646529:DESACI_RS04140
uniprot id: I4D281
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS20205
gene id: 646529:DESACI_RS20205
uniprot id: I4DBC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS19235
gene id: 646529:DESACI_RS19235
uniprot id: I4DAS3
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

646529:DESACI RS08060
gene id: 646529:DESACI_RS08060
uniprot id: I4D4G3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS18245
gene id: 646529:DESACI_RS18245
uniprot id: I4DA76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

646529:DESACI RS10875
gene id: 646529:DESACI_RS10875
uniprot id: I4D617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

646529:DESACI RS14940
gene id: 646529:DESACI_RS14940
uniprot id: I4D8B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

646529:DESACI RS08690
gene id: 646529:DESACI_RS08690
uniprot id: I4D4T8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

646529:DESACI RS13890
gene id: 646529:DESACI_RS13890
uniprot id: I4D7Q5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

646529:DESACI RS14870
gene id: 646529:DESACI_RS14870
uniprot id: I4D8A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

646529:DESACI RS12030
gene id: 646529:DESACI_RS12030
uniprot id: I4D6P6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

646529:DESACI RS05320
gene id: 646529:DESACI_RS05320
uniprot id: I4D2W4
names: Similarity
messages: Belongs to the hemerythrin family.

646529:DESACI RS16045
gene id: 646529:DESACI_RS16045
uniprot id: I4D8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS00270
gene id: 646529:DESACI_RS00270
uniprot id: I4D047
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS19070
gene id: 646529:DESACI_RS19070
uniprot id: I4DAN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

646529:DESACI RS19110
gene id: 646529:DESACI_RS19110
uniprot id: I4DAP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

646529:DESACI RS03815
gene id: 646529:DESACI_RS03815
uniprot id: I4D217
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

646529:DESACI RS15090
gene id: 646529:DESACI_RS15090
uniprot id: I4D8E9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

646529:DESACI RS15470
gene id: 646529:DESACI_RS15470
uniprot id: I4D8M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS17635
gene id: 646529:DESACI_RS17635
uniprot id: I4D9V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

646529:DESACI RS16935
gene id: 646529:DESACI_RS16935
uniprot id: I4D9F9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS00355
gene id: 646529:DESACI_RS00355
uniprot id: I4D067
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

646529:DESACI RS15225
gene id: 646529:DESACI_RS15225
uniprot id: I4D8H6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

646529:DESACI RS10730
gene id: 646529:DESACI_RS10730
uniprot id: I4D5Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

646529:DESACI RS00425
gene id: 646529:DESACI_RS00425
uniprot id: I4D081
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS00695
gene id: 646529:DESACI_RS00695
uniprot id: I4D0A0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS08965
gene id: 646529:DESACI_RS08965
uniprot id: I4D4Y6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

646529:DESACI RS21065
gene id: 646529:DESACI_RS21065
uniprot id: I4DBT7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

646529:DESACI RS03485
gene id: 646529:DESACI_RS03485
uniprot id: I4D1V1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

646529:DESACI RS20890
gene id: 646529:DESACI_RS20890
uniprot id: I4DBQ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS07520
gene id: 646529:DESACI_RS07520
uniprot id: I4D453
names: Similarity
messages: Belongs to the EutP/PduV family.

646529:DESACI RS02865
gene id: 646529:DESACI_RS02865
uniprot id: I4D1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS09710
gene id: 646529:DESACI_RS09710
uniprot id: I4D5D7
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS04240
gene id: 646529:DESACI_RS04240
uniprot id: I4D2A3
names: Similarity
messages: Belongs to the GARS family.

646529:DESACI RS10135
gene id: 646529:DESACI_RS10135
uniprot id: I4D5M1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS01070
gene id: 646529:DESACI_RS01070
uniprot id: I4D0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

646529:DESACI RS08955
gene id: 646529:DESACI_RS08955
uniprot id: I4D4Y4
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS04500
gene id: 646529:DESACI_RS04500
uniprot id: I4D2F1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

646529:DESACI RS13075
gene id: 646529:DESACI_RS13075
uniprot id: I4D7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS13600
gene id: 646529:DESACI_RS13600
uniprot id: I4D7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

646529:DESACI RS10250
gene id: 646529:DESACI_RS10250
uniprot id: I4D5P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

646529:DESACI RS13690
gene id: 646529:DESACI_RS13690
uniprot id: I4D7L4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

646529:DESACI RS07550
gene id: 646529:DESACI_RS07550
uniprot id: I4D459
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

646529:DESACI RS01545
gene id: 646529:DESACI_RS01545
uniprot id: I4D0R3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS08805
gene id: 646529:DESACI_RS08805
uniprot id: I4D4V6
names: Similarity
messages: Belongs to the FemABX family.

646529:DESACI RS13070
gene id: 646529:DESACI_RS13070
uniprot id: I4D7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS01245
gene id: 646529:DESACI_RS01245
uniprot id: I4D0K0
names: Similarity
messages: Belongs to the UPF0045 family.

646529:DESACI RS07060
gene id: 646529:DESACI_RS07060
uniprot id: I4D3W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

646529:DESACI RS15475
gene id: 646529:DESACI_RS15475
uniprot id: I4D8M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

646529:DESACI RS05575
gene id: 646529:DESACI_RS05575
uniprot id: I4D314
names: Similarity
messages: Belongs to the UxaA family.

646529:DESACI RS02525
gene id: 646529:DESACI_RS02525
uniprot id: I4D1A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

646529:DESACI RS05175
gene id: 646529:DESACI_RS05175
uniprot id: I4D2T4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

646529:DESACI RS17075
gene id: 646529:DESACI_RS17075
uniprot id: I4D9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

646529:DESACI RS00990
gene id: 646529:DESACI_RS00990
uniprot id: I4D0F1
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS20595
gene id: 646529:DESACI_RS20595
uniprot id: I4DBJ9
names: Similarity
messages: Belongs to the UPF0111 family.

646529:DESACI RS03225
gene id: 646529:DESACI_RS03225
uniprot id: I4D1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

646529:DESACI RS09145
gene id: 646529:DESACI_RS09145
uniprot id: I4D522
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

646529:DESACI RS13940
gene id: 646529:DESACI_RS13940
uniprot id: I4D7R5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

646529:DESACI RS00285
gene id: 646529:DESACI_RS00285
uniprot id: I4D050
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

646529:DESACI RS16640
gene id: 646529:DESACI_RS16640
uniprot id: I4D9A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

646529:DESACI RS19130
gene id: 646529:DESACI_RS19130
uniprot id: I4DAQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

646529:DESACI RS05450
gene id: 646529:DESACI_RS05450
uniprot id: I4D2Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

646529:DESACI RS03775
gene id: 646529:DESACI_RS03775
uniprot id: I4D210
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

646529:DESACI RS03500
gene id: 646529:DESACI_RS03500
uniprot id: I4D1V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

646529:DESACI RS03560
gene id: 646529:DESACI_RS03560
uniprot id: I4D1W6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

646529:DESACI RS03355
gene id: 646529:DESACI_RS03355
uniprot id: I4D1S6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS02575
gene id: 646529:DESACI_RS02575
uniprot id: I4D1B9
names: Similarity
messages: Belongs to the peptidase M20A family.

646529:DESACI RS04615
gene id: 646529:DESACI_RS04615
uniprot id: I4D2H4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

646529:DESACI RS17750
gene id: 646529:DESACI_RS17750
uniprot id: I4D9X5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

646529:DESACI RS03215
gene id: 646529:DESACI_RS03215
uniprot id: I4D1P6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS08700
gene id: 646529:DESACI_RS08700
uniprot id: I4D4U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

646529:DESACI RS01630
gene id: 646529:DESACI_RS01630
uniprot id: I4D0T0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

646529:DESACI RS04510
gene id: 646529:DESACI_RS04510
uniprot id: I4D2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

646529:DESACI RS14995
gene id: 646529:DESACI_RS14995
uniprot id: I4D8C8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS12640
gene id: 646529:DESACI_RS12640
uniprot id: I4D714
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS20070
gene id: 646529:DESACI_RS20070
uniprot id: I4DB94
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

646529:DESACI RS15875
gene id: 646529:DESACI_RS15875
uniprot id: I4D8V2
names: Similarity
messages: Belongs to the TlyA family.

646529:DESACI RS08175
gene id: 646529:DESACI_RS08175
uniprot id: I4D4I5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

646529:DESACI RS02755
gene id: 646529:DESACI_RS02755
uniprot id: I4D1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

646529:DESACI RS17140
gene id: 646529:DESACI_RS17140
uniprot id: I4D9K1
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS12635
gene id: 646529:DESACI_RS12635
uniprot id: I4D713
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS00780
gene id: 646529:DESACI_RS00780
uniprot id: I4D0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

646529:DESACI RS22515
gene id: 646529:DESACI_RS22515
uniprot id: I4DCM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

646529:DESACI RS13460
gene id: 646529:DESACI_RS13460
uniprot id: I4D7G7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS02585
gene id: 646529:DESACI_RS02585
uniprot id: I4D1C1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

646529:DESACI RS02455
gene id: 646529:DESACI_RS02455
uniprot id: I4D194
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

646529:DESACI RS13925
gene id: 646529:DESACI_RS13925
uniprot id: I4D7R2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS00950
gene id: 646529:DESACI_RS00950
uniprot id: I4D0E4
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13700
gene id: 646529:DESACI_RS13700
uniprot id: I4D7L6
names: Similarity
messages: Belongs to the GerABKA family.

646529:DESACI RS13695
gene id: 646529:DESACI_RS13695
uniprot id: I4D7L5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

646529:DESACI RS00790
gene id: 646529:DESACI_RS00790
uniprot id: I4D0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS15760
gene id: 646529:DESACI_RS15760
uniprot id: I4D8S9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

646529:DESACI RS04760
gene id: 646529:DESACI_RS04760
uniprot id: I4D2K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

646529:DESACI RS13570
gene id: 646529:DESACI_RS13570
uniprot id: I4D7J1
names: Similarity
messages: Belongs to the peptidase C40 family.

646529:DESACI RS16600
gene id: 646529:DESACI_RS16600
uniprot id: I4D997
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

646529:DESACI RS02480
gene id: 646529:DESACI_RS02480
uniprot id: I4D1A0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

646529:DESACI RS14240
gene id: 646529:DESACI_RS14240
uniprot id: I4D7X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

646529:DESACI RS04215
gene id: 646529:DESACI_RS04215
uniprot id: I4D298
names: Similarity
messages: Belongs to the SAICAR synthetase family.

646529:DESACI RS07305
gene id: 646529:DESACI_RS07305
uniprot id: I4D415
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

646529:DESACI RS13245
gene id: 646529:DESACI_RS13245
uniprot id: I4D7D5
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

646529:DESACI RS17135
gene id: 646529:DESACI_RS17135
uniprot id: I4D9K0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS20215
gene id: 646529:DESACI_RS20215
uniprot id: I4DBC6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

646529:DESACI RS03260
gene id: 646529:DESACI_RS03260
uniprot id: I4D1Q6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS04120
gene id: 646529:DESACI_RS04120
uniprot id: I4D277
names: Similarity
messages: Belongs to the Nudix hydrolase family.

646529:DESACI RS08550
gene id: 646529:DESACI_RS08550
uniprot id: I4D4Q9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

646529:DESACI RS04725
gene id: 646529:DESACI_RS04725
uniprot id: I4D2J8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS07230
gene id: 646529:DESACI_RS07230
uniprot id: I4D401
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

646529:DESACI RS05810
gene id: 646529:DESACI_RS05810
uniprot id: I4D358
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS02320
gene id: 646529:DESACI_RS02320
uniprot id: I4D167
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

646529:DESACI RS02735
gene id: 646529:DESACI_RS02735
uniprot id: I4D1F0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS21575
gene id: 646529:DESACI_RS21575
uniprot id: I4DC40
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS00415
gene id: 646529:DESACI_RS00415
uniprot id: I4D079
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

646529:DESACI RS22260
gene id: 646529:DESACI_RS22260
uniprot id: I4DCI0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

646529:DESACI RS00865
gene id: 646529:DESACI_RS00865
uniprot id: I4D0C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

646529:DESACI RS11325
gene id: 646529:DESACI_RS11325
uniprot id: I4D6A8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS01175
gene id: 646529:DESACI_RS01175
uniprot id: I4D0I7
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

646529:DESACI RS07460
gene id: 646529:DESACI_RS07460
uniprot id: I4D441
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

646529:DESACI RS00350
gene id: 646529:DESACI_RS00350
uniprot id: I4D066
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

646529:DESACI RS10445
gene id: 646529:DESACI_RS10445
uniprot id: I4D5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

646529:DESACI RS21500
gene id: 646529:DESACI_RS21500
uniprot id: I4DC25
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS01590
gene id: 646529:DESACI_RS01590
uniprot id: I4D0S2
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08975
gene id: 646529:DESACI_RS08975
uniprot id: I4D4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

646529:DESACI RS16965
gene id: 646529:DESACI_RS16965
uniprot id: I4D9G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

646529:DESACI RS16350
gene id: 646529:DESACI_RS16350
uniprot id: I4D945
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

646529:DESACI RS16080
gene id: 646529:DESACI_RS16080
uniprot id: I4D8Z2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS05080
gene id: 646529:DESACI_RS05080
uniprot id: I4D2R5
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

646529:DESACI RS05865
gene id: 646529:DESACI_RS05865
uniprot id: I4D369
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

646529:DESACI RS19775
gene id: 646529:DESACI_RS19775
uniprot id: I4DB37
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

646529:DESACI RS17885
gene id: 646529:DESACI_RS17885
uniprot id: I4DA02
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

646529:DESACI RS06955
gene id: 646529:DESACI_RS06955
uniprot id: I4D3U9
names: Similarity
messages: Belongs to the peptidase A24 family.

646529:DESACI RS07385
gene id: 646529:DESACI_RS07385
uniprot id: I4D428
names: Similarity
messages: Belongs to the PspA/IM30 family.

646529:DESACI RS16630
gene id: 646529:DESACI_RS16630
uniprot id: I4D9A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

646529:DESACI RS15620
gene id: 646529:DESACI_RS15620
uniprot id: I4D8Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

646529:DESACI RS02650
gene id: 646529:DESACI_RS02650
uniprot id: I4D1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

646529:DESACI RS19155
gene id: 646529:DESACI_RS19155
uniprot id: I4DAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

646529:DESACI RS10490
gene id: 646529:DESACI_RS10490
uniprot id: I4D5U4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

646529:DESACI RS02300
gene id: 646529:DESACI_RS02300
uniprot id: I4D164
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

646529:DESACI RS17385
gene id: 646529:DESACI_RS17385
uniprot id: I4D9Q1
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

646529:DESACI RS07290
gene id: 646529:DESACI_RS07290
uniprot id: I4D412
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

646529:DESACI RS18425
gene id: 646529:DESACI_RS18425
uniprot id: I4DAB4
names: Similarity
messages: Belongs to the bacterial flagellin family.

646529:DESACI RS10840
gene id: 646529:DESACI_RS10840
uniprot id: I4D610
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

646529:DESACI RS05915
gene id: 646529:DESACI_RS05915
uniprot id: I4D379
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

646529:DESACI RS20500
gene id: 646529:DESACI_RS20500
uniprot id: I4DBI1
names: Similarity
messages: Belongs to the transpeptidase family.

646529:DESACI RS23100
gene id: 646529:DESACI_RS23100
uniprot id: I4D6L5
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

646529:DESACI RS03590
gene id: 646529:DESACI_RS03590
uniprot id: I4D1X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

646529:DESACI RS03150
gene id: 646529:DESACI_RS03150
uniprot id: I4D1N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

646529:DESACI RS15940
gene id: 646529:DESACI_RS15940
uniprot id: I4D8W5
names: Similarity
messages: Belongs to the asp23 family.

646529:DESACI RS19215
gene id: 646529:DESACI_RS19215
uniprot id: I4DAR9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

646529:DESACI RS09795
gene id: 646529:DESACI_RS09795
uniprot id: I4D5F4
names: Similarity
messages: Belongs to the carbamate kinase family.

646529:DESACI RS19840
gene id: 646529:DESACI_RS19840
uniprot id: I4DB50
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

646529:DESACI RS16000
gene id: 646529:DESACI_RS16000
uniprot id: I4D8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

646529:DESACI RS14800
gene id: 646529:DESACI_RS14800
uniprot id: I4D892
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS12925
gene id: 646529:DESACI_RS12925
uniprot id: I4D771
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS00405
gene id: 646529:DESACI_RS00405
uniprot id: I4D077
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

646529:DESACI RS22135
gene id: 646529:DESACI_RS22135
uniprot id: I4DCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

646529:DESACI RS21570
gene id: 646529:DESACI_RS21570
uniprot id: I4DC39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS03125
gene id: 646529:DESACI_RS03125
uniprot id: I4D1N0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS18565
gene id: 646529:DESACI_RS18565
uniprot id: I4DAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

646529:DESACI RS10690
gene id: 646529:DESACI_RS10690
uniprot id: I4D5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

646529:DESACI RS14815
gene id: 646529:DESACI_RS14815
uniprot id: I4D894
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

646529:DESACI RS18250
gene id: 646529:DESACI_RS18250
uniprot id: I4DA77
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

646529:DESACI RS00170
gene id: 646529:DESACI_RS00170
uniprot id: I4D027
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS18210
gene id: 646529:DESACI_RS18210
uniprot id: I4DA69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

646529:DESACI RS02620
gene id: 646529:DESACI_RS02620
uniprot id: I4D1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

646529:DESACI RS19015
gene id: 646529:DESACI_RS19015
uniprot id: I4DAM8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

646529:DESACI RS05510
gene id: 646529:DESACI_RS05510
uniprot id: I4D301
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS03105
gene id: 646529:DESACI_RS03105
uniprot id: I4D1M6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS02375
gene id: 646529:DESACI_RS02375
uniprot id: I4D178
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

646529:DESACI RS21565
gene id: 646529:DESACI_RS21565
uniprot id: I4DC38
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS15675
gene id: 646529:DESACI_RS15675
uniprot id: I4D8R2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

646529:DESACI RS20800
gene id: 646529:DESACI_RS20800
uniprot id: I4DBN6
names: Similarity
messages: Belongs to the class-I fumarase family.

646529:DESACI RS22510
gene id: 646529:DESACI_RS22510
uniprot id: I4DCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

646529:DESACI RS17705
gene id: 646529:DESACI_RS17705
uniprot id: I4D9W5
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

646529:DESACI RS17280
gene id: 646529:DESACI_RS17280
uniprot id: I4D9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

646529:DESACI RS10470
gene id: 646529:DESACI_RS10470
uniprot id: I4D5U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

646529:DESACI RS12650
gene id: 646529:DESACI_RS12650
uniprot id: I4D716
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS08610
gene id: 646529:DESACI_RS08610
uniprot id: I4D4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

646529:DESACI RS21365
gene id: 646529:DESACI_RS21365
uniprot id: I4DBZ9
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS09715
gene id: 646529:DESACI_RS09715
uniprot id: I4D5D8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS19530
gene id: 646529:DESACI_RS19530
uniprot id: I4DAY3
names: Similarity
messages: Belongs to the GSP E family.

646529:DESACI RS14350
gene id: 646529:DESACI_RS14350
uniprot id: I4D800
names: Similarity
messages: Belongs to the RNase H family.

646529:DESACI RS00775
gene id: 646529:DESACI_RS00775
uniprot id: I4D0B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

646529:DESACI RS04315
gene id: 646529:DESACI_RS04315
uniprot id: I4D2B4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS03610
gene id: 646529:DESACI_RS03610
uniprot id: I4D1X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

646529:DESACI RS19020
gene id: 646529:DESACI_RS19020
uniprot id: I4DAM9
names: Similarity
messages: Belongs to the KdgT transporter family.

646529:DESACI RS18740
gene id: 646529:DESACI_RS18740
uniprot id: I4DAH6
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

646529:DESACI RS20570
gene id: 646529:DESACI_RS20570
uniprot id: I4DBJ4
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

646529:DESACI RS17255
gene id: 646529:DESACI_RS17255
uniprot id: I4D9M4
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

646529:DESACI RS20360
gene id: 646529:DESACI_RS20360
uniprot id: I4DBF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

646529:DESACI RS10240
gene id: 646529:DESACI_RS10240
uniprot id: I4D5P2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

646529:DESACI RS16675
gene id: 646529:DESACI_RS16675
uniprot id: I4D9B2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

646529:DESACI RS08950
gene id: 646529:DESACI_RS08950
uniprot id: I4D4Y3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

646529:DESACI RS13550
gene id: 646529:DESACI_RS13550
uniprot id: I4D7I7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

646529:DESACI RS18095
gene id: 646529:DESACI_RS18095
uniprot id: I4DA46
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

646529:DESACI RS17995
gene id: 646529:DESACI_RS17995
uniprot id: I4DA24
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

646529:DESACI RS10950
gene id: 646529:DESACI_RS10950
uniprot id: I4D633
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

646529:DESACI RS11615
gene id: 646529:DESACI_RS11615
uniprot id: I4D6G7
names: Similarity
messages: Belongs to the CobH/CbiC family.

646529:DESACI RS10895
gene id: 646529:DESACI_RS10895
uniprot id: I4D622
names: Similarity
messages: Belongs to the type IA topoisomerase family.

646529:DESACI RS07655
gene id: 646529:DESACI_RS07655
uniprot id: I4D481
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

646529:DESACI RS15845
gene id: 646529:DESACI_RS15845
uniprot id: I4D8U7
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS15665
gene id: 646529:DESACI_RS15665
uniprot id: I4D8R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

646529:DESACI RS13765
gene id: 646529:DESACI_RS13765
uniprot id: I4D7N0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS01150
gene id: 646529:DESACI_RS01150
uniprot id: I4D0I3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS15495
gene id: 646529:DESACI_RS15495
uniprot id: I4D8M7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

646529:DESACI RS17185
gene id: 646529:DESACI_RS17185
uniprot id: I4D9L0
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS17820
gene id: 646529:DESACI_RS17820
uniprot id: I4D9Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

646529:DESACI RS02140
gene id: 646529:DESACI_RS02140
uniprot id: I4D131
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

646529:DESACI RS17880
gene id: 646529:DESACI_RS17880
uniprot id: I4DA01
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS15145
gene id: 646529:DESACI_RS15145
uniprot id: I4D8G1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

646529:DESACI RS16500
gene id: 646529:DESACI_RS16500
uniprot id: I4D975
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

646529:DESACI RS17320
gene id: 646529:DESACI_RS17320
uniprot id: I4D9N7
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

646529:DESACI RS03735
gene id: 646529:DESACI_RS03735
uniprot id: I4D202
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

646529:DESACI RS01355
gene id: 646529:DESACI_RS01355
uniprot id: I4D0M3
names: Similarity
messages: Belongs to the UPF0251 family.

646529:DESACI RS11190
gene id: 646529:DESACI_RS11190
uniprot id: I4D681
names: Similarity
messages: Belongs to the TelA family.

646529:DESACI RS06620
gene id: 646529:DESACI_RS06620
uniprot id: I4D3N4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

646529:DESACI RS17330
gene id: 646529:DESACI_RS17330
uniprot id: I4D9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

646529:DESACI RS10480
gene id: 646529:DESACI_RS10480
uniprot id: I4D5U2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS11155
gene id: 646529:DESACI_RS11155
uniprot id: I4D674
names: Similarity
messages: Belongs to the peptidase M29 family.

646529:DESACI RS04020
gene id: 646529:DESACI_RS04020
uniprot id: I4D255
names: Similarity
messages: Belongs to the SfsA family.

646529:DESACI RS03615
gene id: 646529:DESACI_RS03615
uniprot id: I4D1X8
names: Similarity
messages: Belongs to the glutamate synthase family.

646529:DESACI RS19060
gene id: 646529:DESACI_RS19060
uniprot id: I4DAN7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

646529:DESACI RS18970
gene id: 646529:DESACI_RS18970
uniprot id: I4DAL9
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08145
gene id: 646529:DESACI_RS08145
uniprot id: I4D4H9
names: Similarity
messages: Belongs to the peptidase C40 family.

646529:DESACI RS03400
gene id: 646529:DESACI_RS03400
uniprot id: I4D1T4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS02945
gene id: 646529:DESACI_RS02945
uniprot id: I4D1J4
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

646529:DESACI RS10460
gene id: 646529:DESACI_RS10460
uniprot id: I4D5T8
names: Similarity
messages: Belongs to the asparagine synthetase family.

646529:DESACI RS03420
gene id: 646529:DESACI_RS03420
uniprot id: I4D1T8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS10230
gene id: 646529:DESACI_RS10230
uniprot id: I4D5P0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

646529:DESACI RS14845
gene id: 646529:DESACI_RS14845
uniprot id: I4D898
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

646529:DESACI RS07180
gene id: 646529:DESACI_RS07180
uniprot id: I4D3Z1
names: Similarity
messages: Belongs to the CdaR family.

646529:DESACI RS18225
gene id: 646529:DESACI_RS18225
uniprot id: U3GL05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

646529:DESACI RS17380
gene id: 646529:DESACI_RS17380
uniprot id: I4D9Q0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

646529:DESACI RS15630
gene id: 646529:DESACI_RS15630
uniprot id: I4D8Q3
names: Similarity
messages: Belongs to the UPF0251 family.

646529:DESACI RS21820
gene id: 646529:DESACI_RS21820
uniprot id: I4DC92
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

646529:DESACI RS01550
gene id: 646529:DESACI_RS01550
uniprot id: I4D0R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS11075
gene id: 646529:DESACI_RS11075
uniprot id: I4D657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS04720
gene id: 646529:DESACI_RS04720
uniprot id: I4D2J7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS03160
gene id: 646529:DESACI_RS03160
uniprot id: I4D1N7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

646529:DESACI RS14920
gene id: 646529:DESACI_RS14920
uniprot id: I4D8B2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

646529:DESACI RS05275
gene id: 646529:DESACI_RS05275
uniprot id: I4D2V4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS01060
gene id: 646529:DESACI_RS01060
uniprot id: I4D0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

646529:DESACI RS14730
gene id: 646529:DESACI_RS14730
uniprot id: I4D878
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

646529:DESACI RS12435
gene id: 646529:DESACI_RS12435
uniprot id: I4D6X1
names: Similarity
messages: Belongs to the UPF0145 family.

646529:DESACI RS17395
gene id: 646529:DESACI_RS17395
uniprot id: I4D9Q3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

646529:DESACI RS16015
gene id: 646529:DESACI_RS16015
uniprot id: I4D8Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

646529:DESACI RS10700
gene id: 646529:DESACI_RS10700
uniprot id: I4D5Y6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

646529:DESACI RS05285
gene id: 646529:DESACI_RS05285
uniprot id: I4D2V6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS19300
gene id: 646529:DESACI_RS19300
uniprot id: I4DAT6
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS05565
gene id: 646529:DESACI_RS05565
uniprot id: I4D312
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

646529:DESACI RS01605
gene id: 646529:DESACI_RS01605
uniprot id: I4D0S5
names: Similarity
messages: Belongs to the FrhG family.

646529:DESACI RS10350
gene id: 646529:DESACI_RS10350
uniprot id: I4D5R3
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

646529:DESACI RS18300
gene id: 646529:DESACI_RS18300
uniprot id: I4DA87
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

646529:DESACI RS22380
gene id: 646529:DESACI_RS22380
uniprot id: I4DCK0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

646529:DESACI RS01695
gene id: 646529:DESACI_RS01695
uniprot id: I4D0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

646529:DESACI RS01985
gene id: 646529:DESACI_RS01985
uniprot id: I4D0Z9
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

646529:DESACI RS03535
gene id: 646529:DESACI_RS03535
uniprot id: I4D1W1
names: Similarity
messages: Belongs to the manganese catalase family.

646529:DESACI RS17060
gene id: 646529:DESACI_RS17060
uniprot id: I4D9I5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS05560
gene id: 646529:DESACI_RS05560
uniprot id: I4D311
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

646529:DESACI RS02070
gene id: 646529:DESACI_RS02070
uniprot id: I4D116
names: Similarity
messages: Belongs to the UxaA family.

646529:DESACI RS13875
gene id: 646529:DESACI_RS13875
uniprot id: I4D7Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

646529:DESACI RS17460
gene id: 646529:DESACI_RS17460
uniprot id: I4D9R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

646529:DESACI RS19200
gene id: 646529:DESACI_RS19200
uniprot id: I4DAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

646529:DESACI RS11250
gene id: 646529:DESACI_RS11250
uniprot id: I4D693
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08255
gene id: 646529:DESACI_RS08255
uniprot id: I4D4K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS14255
gene id: 646529:DESACI_RS14255
uniprot id: I4D7X9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

646529:DESACI RS07370
gene id: 646529:DESACI_RS07370
uniprot id: I4D424
names: Similarity
messages: Belongs to the DtxR/MntR family.

646529:DESACI RS07505
gene id: 646529:DESACI_RS07505
uniprot id: I4D450
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-824 that is involved in catalysis.

646529:DESACI RS23210
gene id: 646529:DESACI_RS23210
uniprot id: I4DAX8
names: Similarity
messages: Belongs to the intimin/invasin family.

646529:DESACI RS02075
gene id: 646529:DESACI_RS02075
uniprot id: I4D117
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

646529:DESACI RS10685
gene id: 646529:DESACI_RS10685
uniprot id: I4D5Y3
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

646529:DESACI RS16925
gene id: 646529:DESACI_RS16925
uniprot id: I4D9F7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

646529:DESACI RS19805
gene id: 646529:DESACI_RS19805
uniprot id: I4DB43
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

646529:DESACI RS22160
gene id: 646529:DESACI_RS22160
uniprot id: I4DCF8
names: Similarity
messages: Belongs to the FBPase class 2 family.

646529:DESACI RS00835
gene id: 646529:DESACI_RS00835
uniprot id: I4D0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS14705
gene id: 646529:DESACI_RS14705
uniprot id: I4D873
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS18255
gene id: 646529:DESACI_RS18255
uniprot id: I4DA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

646529:DESACI RS02335
gene id: 646529:DESACI_RS02335
uniprot id: I4D170
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

646529:DESACI RS11255
gene id: 646529:DESACI_RS11255
uniprot id: I4D694
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS18120
gene id: 646529:DESACI_RS18120
uniprot id: I4DA51
names: Similarity
messages: Belongs to the MecA family.

646529:DESACI RS22185
gene id: 646529:DESACI_RS22185
uniprot id: I4DCG3
names: Similarity
messages: Belongs to the FemABX family.

646529:DESACI RS04145
gene id: 646529:DESACI_RS04145
uniprot id: I4D282
names: Similarity
messages: Belongs to the TrpC family.

646529:DESACI RS11570
gene id: 646529:DESACI_RS11570
uniprot id: I4D6F8
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

646529:DESACI RS21165
gene id: 646529:DESACI_RS21165
uniprot id: I4DBV8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS09170
gene id: 646529:DESACI_RS09170
uniprot id: I4D527
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

646529:DESACI RS02465
gene id: 646529:DESACI_RS02465
uniprot id: I4D197
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

646529:DESACI RS02775
gene id: 646529:DESACI_RS02775
uniprot id: I4D1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

646529:DESACI RS00045
gene id: 646529:DESACI_RS00045
uniprot id: I4D007
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS14610
gene id: 646529:DESACI_RS14610
uniprot id: I4D854
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

646529:DESACI RS12770
gene id: 646529:DESACI_RS12770
uniprot id: I4D740
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

646529:DESACI RS14525
gene id: 646529:DESACI_RS14525
uniprot id: I4D835
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS22200
gene id: 646529:DESACI_RS22200
uniprot id: I4DCG6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

646529:DESACI RS09230
gene id: 646529:DESACI_RS09230
uniprot id: I4D540
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS15105
gene id: 646529:DESACI_RS15105
uniprot id: I4D8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

646529:DESACI RS20290
gene id: 646529:DESACI_RS20290
uniprot id: I4DBE3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

646529:DESACI RS20725
gene id: 646529:DESACI_RS20725
uniprot id: I4DBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS04035
gene id: 646529:DESACI_RS04035
uniprot id: I4D258
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

646529:DESACI RS22350
gene id: 646529:DESACI_RS22350
uniprot id: I4DCJ4
names: Similarity
messages: Belongs to the peptidase S16 family.

646529:DESACI RS17190
gene id: 646529:DESACI_RS17190
uniprot id: I4D9L1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS18640
gene id: 646529:DESACI_RS18640
uniprot id: I4DAF6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

646529:DESACI RS02845
gene id: 646529:DESACI_RS02845
uniprot id: I4D1H1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS18585
gene id: 646529:DESACI_RS18585
uniprot id: I4DAE5
names: Cofactor
messages: Binds 1 copper ion per subunit.

646529:DESACI RS05855
gene id: 646529:DESACI_RS05855
uniprot id: I4D367
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

646529:DESACI RS16805
gene id: 646529:DESACI_RS16805
uniprot id: I4D9D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

646529:DESACI RS02045
gene id: 646529:DESACI_RS02045
uniprot id: I4D111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

646529:DESACI RS17920
gene id: 646529:DESACI_RS17920
uniprot id: I4DA09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

646529:DESACI RS03730
gene id: 646529:DESACI_RS03730
uniprot id: I4D201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS08085
gene id: 646529:DESACI_RS08085
uniprot id: I4D4G7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

646529:DESACI RS11590
gene id: 646529:DESACI_RS11590
uniprot id: I4D6G2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

646529:DESACI RS00390
gene id: 646529:DESACI_RS00390
uniprot id: I4D074
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

646529:DESACI RS08320
gene id: 646529:DESACI_RS08320
uniprot id: I4D4L3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

646529:DESACI RS08295
gene id: 646529:DESACI_RS08295
uniprot id: I4D4K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

646529:DESACI RS05460
gene id: 646529:DESACI_RS05460
uniprot id: I4D2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS04400
gene id: 646529:DESACI_RS04400
uniprot id: I4D2D0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13115
gene id: 646529:DESACI_RS13115
uniprot id: I4D7A7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

646529:DESACI RS20840
gene id: 646529:DESACI_RS20840
uniprot id: I4DBP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

646529:DESACI RS02550
gene id: 646529:DESACI_RS02550
uniprot id: I4D1B4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS22450
gene id: 646529:DESACI_RS22450
uniprot id: I4DCL4
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

646529:DESACI RS11540
gene id: 646529:DESACI_RS11540
uniprot id: I4D6F2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS13915
gene id: 646529:DESACI_RS13915
uniprot id: I4D7R0
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

646529:DESACI RS19240
gene id: 646529:DESACI_RS19240
uniprot id: I4DAS4
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

646529:DESACI RS15325
gene id: 646529:DESACI_RS15325
uniprot id: I4D8J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

646529:DESACI RS04390
gene id: 646529:DESACI_RS04390
uniprot id: I4D2C8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13930
gene id: 646529:DESACI_RS13930
uniprot id: I4D7R3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS02490
gene id: 646529:DESACI_RS02490
uniprot id: I4D1A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

646529:DESACI RS17055
gene id: 646529:DESACI_RS17055
uniprot id: I4D9I4
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS03970
gene id: 646529:DESACI_RS03970
uniprot id: I4D245
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

646529:DESACI RS14765
gene id: 646529:DESACI_RS14765
uniprot id: I4D885
names: Similarity
messages: Belongs to the glutamine synthetase family.

646529:DESACI RS18280
gene id: 646529:DESACI_RS18280
uniprot id: I4DA83
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

646529:DESACI RS00720
gene id: 646529:DESACI_RS00720
uniprot id: I4D0A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

646529:DESACI RS15640
gene id: 646529:DESACI_RS15640
uniprot id: I4D8Q5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

646529:DESACI RS03650
gene id: 646529:DESACI_RS03650
uniprot id: I4D1Y5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

646529:DESACI RS04635
gene id: 646529:DESACI_RS04635
uniprot id: I4D2H8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

646529:DESACI RS16910
gene id: 646529:DESACI_RS16910
uniprot id: I4D9F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

646529:DESACI RS03545
gene id: 646529:DESACI_RS03545
uniprot id: I4D1W3
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS18960
gene id: 646529:DESACI_RS18960
uniprot id: I4DAL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

646529:DESACI RS16880
gene id: 646529:DESACI_RS16880
uniprot id: I4D9E8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

646529:DESACI RS11385
gene id: 646529:DESACI_RS11385
uniprot id: I4D6C0
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

646529:DESACI RS19275
gene id: 646529:DESACI_RS19275
uniprot id: I4DAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

646529:DESACI RS19325
gene id: 646529:DESACI_RS19325
uniprot id: I4DAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

646529:DESACI RS17770
gene id: 646529:DESACI_RS17770
uniprot id: I4D9X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

646529:DESACI RS11510
gene id: 646529:DESACI_RS11510
uniprot id: I4D6E8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS12605
gene id: 646529:DESACI_RS12605
uniprot id: I4D707
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS04675
gene id: 646529:DESACI_RS04675
uniprot id: I4D2I8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS22105
gene id: 646529:DESACI_RS22105
uniprot id: I4DCE7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

646529:DESACI RS06390
gene id: 646529:DESACI_RS06390
uniprot id: I4D3I0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS20830
gene id: 646529:DESACI_RS20830
uniprot id: I4DBP2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

646529:DESACI RS11395
gene id: 646529:DESACI_RS11395
uniprot id: I4D6C2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

646529:DESACI RS24050
gene id: 646529:DESACI_RS24050
uniprot id: I4DBG2
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

646529:DESACI RS01910
gene id: 646529:DESACI_RS01910
uniprot id: I4D0Y4
names: Similarity
messages: Belongs to the peptidase C56 family.

646529:DESACI RS05305
gene id: 646529:DESACI_RS05305
uniprot id: I4D2W0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

646529:DESACI RS16470
gene id: 646529:DESACI_RS16470
uniprot id: I4D968
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

646529:DESACI RS20485
gene id: 646529:DESACI_RS20485
uniprot id: I4DBH8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

646529:DESACI RS00260
gene id: 646529:DESACI_RS00260
uniprot id: I4D045
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

646529:DESACI RS04690
gene id: 646529:DESACI_RS04690
uniprot id: I4D2J1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

646529:DESACI RS13095
gene id: 646529:DESACI_RS13095
uniprot id: I4D7A6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

646529:DESACI RS07880
gene id: 646529:DESACI_RS07880
uniprot id: I4D4C4
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS04525
gene id: 646529:DESACI_RS04525
uniprot id: I4D2F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

646529:DESACI RS12565
gene id: 646529:DESACI_RS12565
uniprot id: I4D6Z8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS02580
gene id: 646529:DESACI_RS02580
uniprot id: I4D1C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

646529:DESACI RS14880
gene id: 646529:DESACI_RS14880
uniprot id: I4D8A5
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

646529:DESACI RS14000
gene id: 646529:DESACI_RS14000
uniprot id: I4D7S8
names: Similarity
messages: Belongs to the transpeptidase family.

646529:DESACI RS12675
gene id: 646529:DESACI_RS12675
uniprot id: I4D721
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS17025
gene id: 646529:DESACI_RS17025
uniprot id: I4D9H8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

646529:DESACI RS19850
gene id: 646529:DESACI_RS19850
uniprot id: I4DB52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

646529:DESACI RS16445
gene id: 646529:DESACI_RS16445
uniprot id: I4D963
names: Similarity
messages: Belongs to the UPF0473 family.

646529:DESACI RS03165
gene id: 646529:DESACI_RS03165
uniprot id: I4D1N8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

646529:DESACI RS13590
gene id: 646529:DESACI_RS13590
uniprot id: I4D7J5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

646529:DESACI RS09935
gene id: 646529:DESACI_RS09935
uniprot id: I4D5I1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

646529:DESACI RS01830
gene id: 646529:DESACI_RS01830
uniprot id: I4D0W9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

646529:DESACI RS01165
gene id: 646529:DESACI_RS01165
uniprot id: I4D0I5
names: Similarity
messages: Belongs to the CtsR family.

646529:DESACI RS10595
gene id: 646529:DESACI_RS10595
uniprot id: I4D5W4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS19330
gene id: 646529:DESACI_RS19330
uniprot id: I4DAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

646529:DESACI RS08015
gene id: 646529:DESACI_RS08015
uniprot id: I4D4F4
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS05875
gene id: 646529:DESACI_RS05875
uniprot id: I4D371
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

646529:DESACI RS05730
gene id: 646529:DESACI_RS05730
uniprot id: I4D342
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

646529:DESACI RS09330
gene id: 646529:DESACI_RS09330
uniprot id: I4D561
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13120
gene id: 646529:DESACI_RS13120
uniprot id: I4D7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

646529:DESACI RS18145
gene id: 646529:DESACI_RS18145
uniprot id: I4DA56
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

646529:DESACI RS02210
gene id: 646529:DESACI_RS02210
uniprot id: I4D146
names: Similarity
messages: Belongs to the Nudix hydrolase family.

646529:DESACI RS11215
gene id: 646529:DESACI_RS11215
uniprot id: I4D686
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

646529:DESACI RS03325
gene id: 646529:DESACI_RS03325
uniprot id: I4D1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

646529:DESACI RS02695
gene id: 646529:DESACI_RS02695
uniprot id: I4D1E2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS16200
gene id: 646529:DESACI_RS16200
uniprot id: I4D917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

646529:DESACI RS19230
gene id: 646529:DESACI_RS19230
uniprot id: I4DAS2
names: Similarity
messages: Belongs to the NifX/NifY family.

646529:DESACI RS21785
gene id: 646529:DESACI_RS21785
uniprot id: I4DC85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

646529:DESACI RS04235
gene id: 646529:DESACI_RS04235
uniprot id: I4D2A2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

646529:DESACI RS20960
gene id: 646529:DESACI_RS20960
uniprot id: I4DBR7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

646529:DESACI RS07570
gene id: 646529:DESACI_RS07570
uniprot id: I4D463
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

646529:DESACI RS17550
gene id: 646529:DESACI_RS17550
uniprot id: I4D9T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

646529:DESACI RS12390
gene id: 646529:DESACI_RS12390
uniprot id: I4D6W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metal hydrolase YfiT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Possible metal-dependent hydrolase.

646529:DESACI RS15180
gene id: 646529:DESACI_RS15180
uniprot id: I4D8G7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS16955
gene id: 646529:DESACI_RS16955
uniprot id: I4D9G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

646529:DESACI RS19765
gene id: 646529:DESACI_RS19765
uniprot id: I4DB35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

646529:DESACI RS16510
gene id: 646529:DESACI_RS16510
uniprot id: I4D977
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

646529:DESACI RS17745
gene id: 646529:DESACI_RS17745
uniprot id: I4D9X4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

646529:DESACI RS16560
gene id: 646529:DESACI_RS16560
uniprot id: I4D987
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS20650
gene id: 646529:DESACI_RS20650
uniprot id: I4DBK9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

646529:DESACI RS04585
gene id: 646529:DESACI_RS04585
uniprot id: I4D2G8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

646529:DESACI RS09020
gene id: 646529:DESACI_RS09020
uniprot id: I4D4Z7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

646529:DESACI RS02155
gene id: 646529:DESACI_RS02155
uniprot id: I4D134
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS21550
gene id: 646529:DESACI_RS21550
uniprot id: I4DC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

646529:DESACI RS11470
gene id: 646529:DESACI_RS11470
uniprot id: I4D6E0
names: Similarity
messages: Belongs to the peptidase C40 family.

646529:DESACI RS22490
gene id: 646529:DESACI_RS22490
uniprot id: I4DCM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

646529:DESACI RS01250
gene id: 646529:DESACI_RS01250
uniprot id: I4D0K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS00210
gene id: 646529:DESACI_RS00210
uniprot id: I4D035
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

646529:DESACI RS22385
gene id: 646529:DESACI_RS22385
uniprot id: I4DCK1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

646529:DESACI RS20090
gene id: 646529:DESACI_RS20090
uniprot id: I4DB99
names: Similarity
messages: Belongs to the UPF0597 family.

646529:DESACI RS02405
gene id: 646529:DESACI_RS02405
uniprot id: I4D184
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

646529:DESACI RS07075
gene id: 646529:DESACI_RS07075
uniprot id: I4D3X1
names: Similarity
messages: Belongs to the DtxR/MntR family.

646529:DESACI RS15880
gene id: 646529:DESACI_RS15880
uniprot id: I4D8V3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

646529:DESACI RS15870
gene id: 646529:DESACI_RS15870
uniprot id: I4D8V1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS09200
gene id: 646529:DESACI_RS09200
uniprot id: I4D533
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

646529:DESACI RS19150
gene id: 646529:DESACI_RS19150
uniprot id: I4DAQ5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

646529:DESACI RS14370
gene id: 646529:DESACI_RS14370
uniprot id: I4D804
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

646529:DESACI RS08605
gene id: 646529:DESACI_RS08605
uniprot id: I4D4S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

646529:DESACI RS14030
gene id: 646529:DESACI_RS14030
uniprot id: I4D7T5
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

646529:DESACI RS13010
gene id: 646529:DESACI_RS13010
uniprot id: I4D789
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

646529:DESACI RS16930
gene id: 646529:DESACI_RS16930
uniprot id: I4D9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

646529:DESACI RS11845
gene id: 646529:DESACI_RS11845
uniprot id: I4D6K7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

646529:DESACI RS11870
gene id: 646529:DESACI_RS11870
uniprot id: I4D6L2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

646529:DESACI RS14070
gene id: 646529:DESACI_RS14070
uniprot id: I4D7U3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

646529:DESACI RS09135
gene id: 646529:DESACI_RS09135
uniprot id: I4D520
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

646529:DESACI RS18100
gene id: 646529:DESACI_RS18100
uniprot id: I4DA47
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

646529:DESACI RS03375
gene id: 646529:DESACI_RS03375
uniprot id: I4D1T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

646529:DESACI RS06860
gene id: 646529:DESACI_RS06860
uniprot id: I4D3S9
names: Similarity
messages: Belongs to the GSP E family.

646529:DESACI RS12200
gene id: 646529:DESACI_RS12200
uniprot id: I4D6T0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS15440
gene id: 646529:DESACI_RS15440
uniprot id: I4D8L6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

646529:DESACI RS08695
gene id: 646529:DESACI_RS08695
uniprot id: I4D4T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

646529:DESACI RS15785
gene id: 646529:DESACI_RS15785
uniprot id: I4D8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

646529:DESACI RS12600
gene id: 646529:DESACI_RS12600
uniprot id: I4D706
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS02415
gene id: 646529:DESACI_RS02415
uniprot id: I4D186
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

646529:DESACI RS15315
gene id: 646529:DESACI_RS15315
uniprot id: I4D8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

646529:DESACI RS07040
gene id: 646529:DESACI_RS07040
uniprot id: I4D3W5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

646529:DESACI RS01065
gene id: 646529:DESACI_RS01065
uniprot id: I4D0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

646529:DESACI RS14050
gene id: 646529:DESACI_RS14050
uniprot id: I4D7T9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS02505
gene id: 646529:DESACI_RS02505
uniprot id: I4D1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

646529:DESACI RS13525
gene id: 646529:DESACI_RS13525
uniprot id: I4D7I2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

646529:DESACI RS21540
gene id: 646529:DESACI_RS21540
uniprot id: I4DC33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS08425
gene id: 646529:DESACI_RS08425
uniprot id: I4D4N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

646529:DESACI RS08455
gene id: 646529:DESACI_RS08455
uniprot id: I4D4P0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

646529:DESACI RS03475
gene id: 646529:DESACI_RS03475
uniprot id: I4D1U9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

646529:DESACI RS11240
gene id: 646529:DESACI_RS11240
uniprot id: I4D691
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS14575
gene id: 646529:DESACI_RS14575
uniprot id: I4D847
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

646529:DESACI RS17170
gene id: 646529:DESACI_RS17170
uniprot id: I4D9K7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS02540
gene id: 646529:DESACI_RS02540
uniprot id: I4D1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

646529:DESACI RS00430
gene id: 646529:DESACI_RS00430
uniprot id: I4D082
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

646529:DESACI RS14320
gene id: 646529:DESACI_RS14320
uniprot id: I4D7Z3
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS22330
gene id: 646529:DESACI_RS22330
uniprot id: I4DCJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

646529:DESACI RS11135
gene id: 646529:DESACI_RS11135
uniprot id: I4D670
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

646529:DESACI RS14265
gene id: 646529:DESACI_RS14265
uniprot id: I4D7Y2
names: Similarity
messages: Belongs to the peptidase M18 family.

646529:DESACI RS02470
gene id: 646529:DESACI_RS02470
uniprot id: I4D198
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

646529:DESACI RS15685
gene id: 646529:DESACI_RS15685
uniprot id: I4D8R4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

646529:DESACI RS01455
gene id: 646529:DESACI_RS01455
uniprot id: I4D0P2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

646529:DESACI RS18870
gene id: 646529:DESACI_RS18870
uniprot id: I4DAK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

646529:DESACI RS02430
gene id: 646529:DESACI_RS02430
uniprot id: I4D189
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

646529:DESACI RS00125
gene id: 646529:DESACI_RS00125
uniprot id: I4D018
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

646529:DESACI RS15050
gene id: 646529:DESACI_RS15050
uniprot id: I4D8D9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

646529:DESACI RS10280
gene id: 646529:DESACI_RS10280
uniprot id: I4D5P9
names: Similarity
messages: Belongs to the PspA/IM30 family.

646529:DESACI RS00100
gene id: 646529:DESACI_RS00100
uniprot id: I4D013
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

646529:DESACI RS02420
gene id: 646529:DESACI_RS02420
uniprot id: I4D187
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

646529:DESACI RS10540
gene id: 646529:DESACI_RS10540
uniprot id: I4D5V3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS11715
gene id: 646529:DESACI_RS11715
uniprot id: I4D6I4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

646529:DESACI RS22215
gene id: 646529:DESACI_RS22215
uniprot id: I4DCG9
names: Similarity
messages: Belongs to the SleB family.

646529:DESACI RS01180
gene id: 646529:DESACI_RS01180
uniprot id: I4D0I8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

646529:DESACI RS20265
gene id: 646529:DESACI_RS20265
uniprot id: I4DBD8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

646529:DESACI RS22240
gene id: 646529:DESACI_RS22240
uniprot id: I4DCH6
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS05005
gene id: 646529:DESACI_RS05005
uniprot id: I4D2Q1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

646529:DESACI RS05110
gene id: 646529:DESACI_RS05110
uniprot id: I4D2S1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

646529:DESACI RS20285
gene id: 646529:DESACI_RS20285
uniprot id: I4DBE2
names: Similarity
messages: Belongs to the DprA/Smf family.

646529:DESACI RS13675
gene id: 646529:DESACI_RS13675
uniprot id: I4D7L1
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS22110
gene id: 646529:DESACI_RS22110
uniprot id: I4DCE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS21535
gene id: 646529:DESACI_RS21535
uniprot id: I4DC32
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

646529:DESACI RS16390
gene id: 646529:DESACI_RS16390
uniprot id: I4D953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

646529:DESACI RS21775
gene id: 646529:DESACI_RS21775
uniprot id: I4DC83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

646529:DESACI RS07625
gene id: 646529:DESACI_RS07625
uniprot id: I4D474
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS21260
gene id: 646529:DESACI_RS21260
uniprot id: I4DBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

646529:DESACI RS22235
gene id: 646529:DESACI_RS22235
uniprot id: I4DCH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

646529:DESACI RS23025
gene id: 646529:DESACI_RS23025
uniprot id: I4D4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

646529:DESACI RS04155
gene id: 646529:DESACI_RS04155
uniprot id: I4D284
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

646529:DESACI RS21840
gene id: 646529:DESACI_RS21840
uniprot id: I4DC96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

646529:DESACI RS22230
gene id: 646529:DESACI_RS22230
uniprot id: I4DCH2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

646529:DESACI RS16875
gene id: 646529:DESACI_RS16875
uniprot id: I4D9E7
names: Similarity
messages: Belongs to the ribF family.

646529:DESACI RS00065
gene id: 646529:DESACI_RS00065
uniprot id: I4D008
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

646529:DESACI RS18410
gene id: 646529:DESACI_RS18410
uniprot id: I4DAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

646529:DESACI RS18330
gene id: 646529:DESACI_RS18330
uniprot id: U3GJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

646529:DESACI RS01935
gene id: 646529:DESACI_RS01935
uniprot id: I4D0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

646529:DESACI RS01940
gene id: 646529:DESACI_RS01940
uniprot id: I4D0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

646529:DESACI RS03600
gene id: 646529:DESACI_RS03600
uniprot id: I4D1X4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

646529:DESACI RS13285
gene id: 646529:DESACI_RS13285
uniprot id: I4D7E3
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS04150
gene id: 646529:DESACI_RS04150
uniprot id: I4D283
names: Similarity
messages: Belongs to the TrpF family.

646529:DESACI RS04645
gene id: 646529:DESACI_RS04645
uniprot id: I4D2I0
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

646529:DESACI RS20955
gene id: 646529:DESACI_RS20955
uniprot id: I4DBR6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

646529:DESACI RS10260
gene id: 646529:DESACI_RS10260
uniprot id: I4D5P6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS15795
gene id: 646529:DESACI_RS15795
uniprot id: I4D8T6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

646529:DESACI RS09220
gene id: 646529:DESACI_RS09220
uniprot id: I4D537
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

646529:DESACI RS04520
gene id: 646529:DESACI_RS04520
uniprot id: I4D2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

646529:DESACI RS01210
gene id: 646529:DESACI_RS01210
uniprot id: I4D0J4
names: Similarity
messages: Belongs to the rubredoxin family.

646529:DESACI RS19010
gene id: 646529:DESACI_RS19010
uniprot id: I4DAM7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS19290
gene id: 646529:DESACI_RS19290
uniprot id: I4DAT4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

646529:DESACI RS18795
gene id: 646529:DESACI_RS18795
uniprot id: I4DAI7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS00700
gene id: 646529:DESACI_RS00700
uniprot id: I4D0A1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS20385
gene id: 646529:DESACI_RS20385
uniprot id: I4DBF8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08315
gene id: 646529:DESACI_RS08315
uniprot id: I4D4L2
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

646529:DESACI RS07575
gene id: 646529:DESACI_RS07575
uniprot id: I4D464
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

646529:DESACI RS17655
gene id: 646529:DESACI_RS17655
uniprot id: I4D9V5
names: Similarity
messages: Belongs to the RemA family.

646529:DESACI RS05520
gene id: 646529:DESACI_RS05520
uniprot id: I4D303
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

646529:DESACI RS22545
gene id: 646529:DESACI_RS22545
uniprot id: I4DCN1
names: Similarity
messages: Belongs to the GSP E family.

646529:DESACI RS00870
gene id: 646529:DESACI_RS00870
uniprot id: I4D0C9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

646529:DESACI RS08300
gene id: 646529:DESACI_RS08300
uniprot id: I4D4K9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

646529:DESACI RS19475
gene id: 646529:DESACI_RS19475
uniprot id: I4DAX0
names: Similarity
messages: Belongs to the GSP E family.

646529:DESACI RS07945
gene id: 646529:DESACI_RS07945
uniprot id: I4D4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS10420
gene id: 646529:DESACI_RS10420
uniprot id: I4D5S8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS07590
gene id: 646529:DESACI_RS07590
uniprot id: I4D467
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS16555
gene id: 646529:DESACI_RS16555
uniprot id: I4D986
names: Similarity
messages: Belongs to the RecJ family.

646529:DESACI RS10900
gene id: 646529:DESACI_RS10900
uniprot id: I4D623
names: Similarity
messages: Belongs to the DEAD box helicase family.

646529:DESACI RS21970
gene id: 646529:DESACI_RS21970
uniprot id: I4DCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS17565
gene id: 646529:DESACI_RS17565
uniprot id: I4D9T7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08130
gene id: 646529:DESACI_RS08130
uniprot id: I4D4H6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

646529:DESACI RS07985
gene id: 646529:DESACI_RS07985
uniprot id: I4D4E8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

646529:DESACI RS10275
gene id: 646529:DESACI_RS10275
uniprot id: I4D5P8
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

646529:DESACI RS18155
gene id: 646529:DESACI_RS18155
uniprot id: I4DA58
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

646529:DESACI RS01200
gene id: 646529:DESACI_RS01200
uniprot id: I4D0J2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

646529:DESACI RS12755
gene id: 646529:DESACI_RS12755
uniprot id: I4D736
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS21265
gene id: 646529:DESACI_RS21265
uniprot id: I4DBX9
names: Similarity
messages: Belongs to the P(II) protein family.

646529:DESACI RS02460
gene id: 646529:DESACI_RS02460
uniprot id: I4D196
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

646529:DESACI RS06430
gene id: 646529:DESACI_RS06430
uniprot id: I4D3J0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS24010
gene id: 646529:DESACI_RS24010
uniprot id: I4D9Z4
names: Subcellular Location Annotation
messages: Cytoplasm

646529:DESACI RS03780
gene id: 646529:DESACI_RS03780
uniprot id: I4D211
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

646529:DESACI RS13820
gene id: 646529:DESACI_RS13820
uniprot id: I4D7P0
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

646529:DESACI RS12620
gene id: 646529:DESACI_RS12620
uniprot id: I4D710
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS16585
gene id: 646529:DESACI_RS16585
uniprot id: I4D994
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

646529:DESACI RS20170
gene id: 646529:DESACI_RS20170
uniprot id: I4DBB7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

646529:DESACI RS02515
gene id: 646529:DESACI_RS02515
uniprot id: I4D1A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

646529:DESACI RS21760
gene id: 646529:DESACI_RS21760
uniprot id: I4DC80
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

646529:DESACI RS00370
gene id: 646529:DESACI_RS00370
uniprot id: I4D070
names: Similarity
messages: Belongs to the UPF0749 family.

646529:DESACI RS15570
gene id: 646529:DESACI_RS15570
uniprot id: I4D8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

646529:DESACI RS22405
gene id: 646529:DESACI_RS22405
uniprot id: I4DCK5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS20490
gene id: 646529:DESACI_RS20490
uniprot id: I4DBH9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

646529:DESACI RS04330
gene id: 646529:DESACI_RS04330
uniprot id: I4D2B7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS17495
gene id: 646529:DESACI_RS17495
uniprot id: I4D9S4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

646529:DESACI RS10970
gene id: 646529:DESACI_RS10970
uniprot id: I4D637
names: Similarity
messages: Belongs to the HdrA family.

646529:DESACI RS18185
gene id: 646529:DESACI_RS18185
uniprot id: I4DA64
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

646529:DESACI RS16765
gene id: 646529:DESACI_RS16765
uniprot id: I4D9C6
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS19900
gene id: 646529:DESACI_RS19900
uniprot id: I4DB62
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS19950
gene id: 646529:DESACI_RS19950
uniprot id: I4DB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

646529:DESACI RS16680
gene id: 646529:DESACI_RS16680
uniprot id: I4D9B3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

646529:DESACI RS13825
gene id: 646529:DESACI_RS13825
uniprot id: I4D7P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

646529:DESACI RS12440
gene id: 646529:DESACI_RS12440
uniprot id: I4D6X2
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS03900
gene id: 646529:DESACI_RS03900
uniprot id: I4D233
names: Similarity
messages: Belongs to the DinB family.

646529:DESACI RS08705
gene id: 646529:DESACI_RS08705
uniprot id: I4D4U1
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

646529:DESACI RS01075
gene id: 646529:DESACI_RS01075
uniprot id: I4D0G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

646529:DESACI RS11200
gene id: 646529:DESACI_RS11200
uniprot id: I4D683
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

646529:DESACI RS20525
gene id: 646529:DESACI_RS20525
uniprot id: I4DBI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

646529:DESACI RS09180
gene id: 646529:DESACI_RS09180
uniprot id: I4D529
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

646529:DESACI RS08380
gene id: 646529:DESACI_RS08380
uniprot id: I4D4M6
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13630
gene id: 646529:DESACI_RS13630
uniprot id: I4D7K3
names: Similarity
messages: Belongs to the peptidase S11 family.

646529:DESACI RS11360
gene id: 646529:DESACI_RS11360
uniprot id: I4D6B5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS20660
gene id: 646529:DESACI_RS20660
uniprot id: I4DBL1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

646529:DESACI RS23345
gene id: 646529:DESACI_RS23345
uniprot id: I4DCV2
names: Similarity
messages: Belongs to the MobA/MobL family.

646529:DESACI RS12800
gene id: 646529:DESACI_RS12800
uniprot id: I4D746
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

646529:DESACI RS15215
gene id: 646529:DESACI_RS15215
uniprot id: I4D8H4
names: Similarity
messages: Belongs to the peptidase S58 family.

646529:DESACI RS14565
gene id: 646529:DESACI_RS14565
uniprot id: I4D845
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS22495
gene id: 646529:DESACI_RS22495
uniprot id: I4DCM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

646529:DESACI RS12980
gene id: 646529:DESACI_RS12980
uniprot id: I4D782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

646529:DESACI RS02500
gene id: 646529:DESACI_RS02500
uniprot id: I4D1A4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

646529:DESACI RS17435
gene id: 646529:DESACI_RS17435
uniprot id: I4D9R1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

646529:DESACI RS01955
gene id: 646529:DESACI_RS01955
uniprot id: I4D0Z3
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

646529:DESACI RS15905
gene id: 646529:DESACI_RS15905
uniprot id: I4D8V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

646529:DESACI RS04775
gene id: 646529:DESACI_RS04775
uniprot id: I4D2K8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

646529:DESACI RS11180
gene id: 646529:DESACI_RS11180
uniprot id: I4D679
names: Similarity
messages: Belongs to the ArsC family.

646529:DESACI RS13805
gene id: 646529:DESACI_RS13805
uniprot id: I4D7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS14340
gene id: 646529:DESACI_RS14340
uniprot id: I4D7Z8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

646529:DESACI RS10170
gene id: 646529:DESACI_RS10170
uniprot id: I4D5M8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

646529:DESACI RS00090
gene id: 646529:DESACI_RS00090
uniprot id: I4D011
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

646529:DESACI RS21555
gene id: 646529:DESACI_RS21555
uniprot id: I4DC36
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS17420
gene id: 646529:DESACI_RS17420
uniprot id: I4D9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

646529:DESACI RS21795
gene id: 646529:DESACI_RS21795
uniprot id: I4DC87
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

646529:DESACI RS00435
gene id: 646529:DESACI_RS00435
uniprot id: I4D083
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

646529:DESACI RS15925
gene id: 646529:DESACI_RS15925
uniprot id: I4D8W2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

646529:DESACI RS02410
gene id: 646529:DESACI_RS02410
uniprot id: I4D185
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

646529:DESACI RS19135
gene id: 646529:DESACI_RS19135
uniprot id: I4DAQ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

646529:DESACI RS21835
gene id: 646529:DESACI_RS21835
uniprot id: I4DC95
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

646529:DESACI RS07585
gene id: 646529:DESACI_RS07585
uniprot id: I4D466
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS14670
gene id: 646529:DESACI_RS14670
uniprot id: I4D866
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

646529:DESACI RS03635
gene id: 646529:DESACI_RS03635
uniprot id: I4D1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

646529:DESACI RS12965
gene id: 646529:DESACI_RS12965
uniprot id: I4D779
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS11050
gene id: 646529:DESACI_RS11050
uniprot id: I4D652
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

646529:DESACI RS16590
gene id: 646529:DESACI_RS16590
uniprot id: I4D995
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

646529:DESACI RS16745
gene id: 646529:DESACI_RS16745
uniprot id: I4D9C2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

646529:DESACI RS08155
gene id: 646529:DESACI_RS08155
uniprot id: I4D4I1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS17795
gene id: 646529:DESACI_RS17795
uniprot id: I4D9Y4
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

646529:DESACI RS15500
gene id: 646529:DESACI_RS15500
uniprot id: I4D8M8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

646529:DESACI RS20870
gene id: 646529:DESACI_RS20870
uniprot id: I4DBQ0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13955
gene id: 646529:DESACI_RS13955
uniprot id: I4D7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

646529:DESACI RS02535
gene id: 646529:DESACI_RS02535
uniprot id: I4D1B1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

646529:DESACI RS16465
gene id: 646529:DESACI_RS16465
uniprot id: I4D967
names: Similarity
messages: Belongs to the UPF0297 family.

646529:DESACI RS01580
gene id: 646529:DESACI_RS01580
uniprot id: I4D0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

646529:DESACI RS22055
gene id: 646529:DESACI_RS22055
uniprot id: I4DCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

646529:DESACI RS11270
gene id: 646529:DESACI_RS11270
uniprot id: I4D697
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

646529:DESACI RS15290
gene id: 646529:DESACI_RS15290
uniprot id: I4D8I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

646529:DESACI RS03845
gene id: 646529:DESACI_RS03845
uniprot id: I4D223
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

646529:DESACI RS16530
gene id: 646529:DESACI_RS16530
uniprot id: I4D981
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS19140
gene id: 646529:DESACI_RS19140
uniprot id: I4DAQ3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

646529:DESACI RS00250
gene id: 646529:DESACI_RS00250
uniprot id: I4D043
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

646529:DESACI RS10290
gene id: 646529:DESACI_RS10290
uniprot id: I4D5Q2
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS16985
gene id: 646529:DESACI_RS16985
uniprot id: I4D9H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

646529:DESACI RS16695
gene id: 646529:DESACI_RS16695
uniprot id: I4D9B6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

646529:DESACI RS03810
gene id: 646529:DESACI_RS03810
uniprot id: I4D216
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

646529:DESACI RS04045
gene id: 646529:DESACI_RS04045
uniprot id: I4D260
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS20235
gene id: 646529:DESACI_RS20235
uniprot id: I4DBD0
names: Similarity
messages: Belongs to the UPF0251 family.

646529:DESACI RS17830
gene id: 646529:DESACI_RS17830
uniprot id: I4D9Z1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

646529:DESACI RS12900
gene id: 646529:DESACI_RS12900
uniprot id: I4D765
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

646529:DESACI RS21870
gene id: 646529:DESACI_RS21870
uniprot id: I4DCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

646529:DESACI RS17125
gene id: 646529:DESACI_RS17125
uniprot id: I4D9J8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

646529:DESACI RS16515
gene id: 646529:DESACI_RS16515
uniprot id: I4D978
names: Similarity
messages: Belongs to the thioredoxin family.

646529:DESACI RS03470
gene id: 646529:DESACI_RS03470
uniprot id: I4D1U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

646529:DESACI RS04220
gene id: 646529:DESACI_RS04220
uniprot id: I4D299
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

646529:DESACI RS04610
gene id: 646529:DESACI_RS04610
uniprot id: I4D2H3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

646529:DESACI RS17730
gene id: 646529:DESACI_RS17730
uniprot id: I4D9X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

646529:DESACI RS02520
gene id: 646529:DESACI_RS02520
uniprot id: I4D1A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

646529:DESACI RS18985
gene id: 646529:DESACI_RS18985
uniprot id: I4DAM2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS15865
gene id: 646529:DESACI_RS15865
uniprot id: I4D8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

646529:DESACI RS03505
gene id: 646529:DESACI_RS03505
uniprot id: I4D1V5
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS19640
gene id: 646529:DESACI_RS19640
uniprot id: I4DB05
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

646529:DESACI RS14200
gene id: 646529:DESACI_RS14200
uniprot id: I4D7W8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

646529:DESACI RS11650
gene id: 646529:DESACI_RS11650
uniprot id: I4D6H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

646529:DESACI RS21605
gene id: 646529:DESACI_RS21605
uniprot id: I4DC48
names: Similarity
messages: Belongs to the AlaDH/PNT family.

646529:DESACI RS03695
gene id: 646529:DESACI_RS03695
uniprot id: I4D1Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS03300
gene id: 646529:DESACI_RS03300
uniprot id: I4D1R5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS17735
gene id: 646529:DESACI_RS17735
uniprot id: I4D9X2
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

646529:DESACI RS17440
gene id: 646529:DESACI_RS17440
uniprot id: I4D9R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

646529:DESACI RS05870
gene id: 646529:DESACI_RS05870
uniprot id: I4D370
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

646529:DESACI RS20835
gene id: 646529:DESACI_RS20835
uniprot id: I4DBP3
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

646529:DESACI RS16850
gene id: 646529:DESACI_RS16850
uniprot id: I4D9E2
names: Similarity
messages: Belongs to the peptidase M16 family.

646529:DESACI RS02815
gene id: 646529:DESACI_RS02815
uniprot id: I4D1G5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS01155
gene id: 646529:DESACI_RS01155
uniprot id: I4D0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

646529:DESACI RS20350
gene id: 646529:DESACI_RS20350
uniprot id: I4DBF0
names: Function
names: Similarity
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.

646529:DESACI RS16115
gene id: 646529:DESACI_RS16115
uniprot id: I4D8Z9
names: Similarity
messages: Belongs to the DltD family.

646529:DESACI RS12525
gene id: 646529:DESACI_RS12525
uniprot id: I4D6Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

646529:DESACI RS15860
gene id: 646529:DESACI_RS15860
uniprot id: I4D8U9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

646529:DESACI RS04160
gene id: 646529:DESACI_RS04160
uniprot id: I4D285
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

646529:DESACI RS16550
gene id: 646529:DESACI_RS16550
uniprot id: I4D985
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS14715
gene id: 646529:DESACI_RS14715
uniprot id: I4D875
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

646529:DESACI RS14710
gene id: 646529:DESACI_RS14710
uniprot id: I4D874
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

646529:DESACI RS02390
gene id: 646529:DESACI_RS02390
uniprot id: I4D181
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

646529:DESACI RS18400
gene id: 646529:DESACI_RS18400
uniprot id: I4DAA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

646529:DESACI RS16690
gene id: 646529:DESACI_RS16690
uniprot id: I4D9B5
names: Similarity
messages: Belongs to the peptidase A31 family.

646529:DESACI RS08655
gene id: 646529:DESACI_RS08655
uniprot id: I4D4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

646529:DESACI RS04780
gene id: 646529:DESACI_RS04780
uniprot id: I4D2K9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

646529:DESACI RS02080
gene id: 646529:DESACI_RS02080
uniprot id: I4D118
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

646529:DESACI RS15300
gene id: 646529:DESACI_RS15300
uniprot id: I4D8J1
names: Similarity
messages: Belongs to the CinA family.

646529:DESACI RS08450
gene id: 646529:DESACI_RS08450
uniprot id: I4D4N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

646529:DESACI RS20060
gene id: 646529:DESACI_RS20060
uniprot id: I4DB92
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS05770
gene id: 646529:DESACI_RS05770
uniprot id: I4D350
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

646529:DESACI RS18475
gene id: 646529:DESACI_RS18475
uniprot id: I4DAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

646529:DESACI RS09205
gene id: 646529:DESACI_RS09205
uniprot id: I4D534
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

646529:DESACI RS20185
gene id: 646529:DESACI_RS20185
uniprot id: I4DBC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

646529:DESACI RS20680
gene id: 646529:DESACI_RS20680
uniprot id: I4DBL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS21300
gene id: 646529:DESACI_RS21300
uniprot id: I4DBY6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

646529:DESACI RS21620
gene id: 646529:DESACI_RS21620
uniprot id: I4DC51
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

646529:DESACI RS07250
gene id: 646529:DESACI_RS07250
uniprot id: I4D405
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

646529:DESACI RS09245
gene id: 646529:DESACI_RS09245
uniprot id: I4D543
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

646529:DESACI RS07495
gene id: 646529:DESACI_RS07495
uniprot id: I4D448
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

646529:DESACI RS21410
gene id: 646529:DESACI_RS21410
uniprot id: I4DC08
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

646529:DESACI RS10775
gene id: 646529:DESACI_RS10775
uniprot id: I4D5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

646529:DESACI RS21070
gene id: 646529:DESACI_RS21070
uniprot id: I4DBT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS21510
gene id: 646529:DESACI_RS21510
uniprot id: I4DC27
names: Similarity
messages: Belongs to the leucine-binding protein family.

646529:DESACI RS04560
gene id: 646529:DESACI_RS04560
uniprot id: I4D2G3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

646529:DESACI RS23350
gene id: 646529:DESACI_RS23350
uniprot id: I4CZZ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

646529:DESACI RS09290
gene id: 646529:DESACI_RS09290
uniprot id: I4D553
names: Similarity
messages: Belongs to the peptidase C1 family.

646529:DESACI RS17305
gene id: 646529:DESACI_RS17305
uniprot id: I4D9N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

646529:DESACI RS11410
gene id: 646529:DESACI_RS11410
uniprot id: I4D6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS08305
gene id: 646529:DESACI_RS08305
uniprot id: I4D4L0
names: Similarity
messages: Belongs to the peptidase M29 family.

646529:DESACI RS15400
gene id: 646529:DESACI_RS15400
uniprot id: I4D8L2
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS00980
gene id: 646529:DESACI_RS00980
uniprot id: I4D0E9
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

646529:DESACI RS12685
gene id: 646529:DESACI_RS12685
uniprot id: I4D723
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

646529:DESACI RS15170
gene id: 646529:DESACI_RS15170
uniprot id: I4D8G5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS13140
gene id: 646529:DESACI_RS13140
uniprot id: I4D7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

646529:DESACI RS18660
gene id: 646529:DESACI_RS18660
uniprot id: I4DAG0
names: Similarity
messages: Belongs to the PspA/IM30 family.

646529:DESACI RS17590
gene id: 646529:DESACI_RS17590
uniprot id: I4D9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

646529:DESACI RS13540
gene id: 646529:DESACI_RS13540
uniprot id: I4D7I5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

646529:DESACI RS15950
gene id: 646529:DESACI_RS15950
uniprot id: I4D8W7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

646529:DESACI RS01920
gene id: 646529:DESACI_RS01920
uniprot id: I4D0Y6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS15670
gene id: 646529:DESACI_RS15670
uniprot id: I4D8R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

646529:DESACI RS19205
gene id: 646529:DESACI_RS19205
uniprot id: I4DAR7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

646529:DESACI RS22475
gene id: 646529:DESACI_RS22475
uniprot id: I4DCL9
names: Similarity
messages: Belongs to the ParB family.

646529:DESACI RS09060
gene id: 646529:DESACI_RS09060
uniprot id: I4D505
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

646529:DESACI RS05545
gene id: 646529:DESACI_RS05545
uniprot id: I4D308
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

646529:DESACI RS21285
gene id: 646529:DESACI_RS21285
uniprot id: I4DBY3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS21210
gene id: 646529:DESACI_RS21210
uniprot id: I4DBW8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

646529:DESACI RS09315
gene id: 646529:DESACI_RS09315
uniprot id: I4D558
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS10655
gene id: 646529:DESACI_RS10655
uniprot id: I4D5X7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

646529:DESACI RS03790
gene id: 646529:DESACI_RS03790
uniprot id: I4D213
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

646529:DESACI RS04730
gene id: 646529:DESACI_RS04730
uniprot id: I4D2J9
names: Similarity
messages: Belongs to the leucine-binding protein family.

646529:DESACI RS20520
gene id: 646529:DESACI_RS20520
uniprot id: I4DBI5
names: Similarity
messages: Belongs to the UPF0758 family.

646529:DESACI RS11430
gene id: 646529:DESACI_RS11430
uniprot id: I4D6C9
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS02715
gene id: 646529:DESACI_RS02715
uniprot id: I4D1E6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS17855
gene id: 646529:DESACI_RS17855
uniprot id: I4D9Z6
names: Similarity
messages: Belongs to the YggT family.

646529:DESACI RS16050
gene id: 646529:DESACI_RS16050
uniprot id: I4D8Y7
names: Similarity
messages: Belongs to the GSP E family.

646529:DESACI RS14620
gene id: 646529:DESACI_RS14620
uniprot id: I4D856
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

646529:DESACI RS03605
gene id: 646529:DESACI_RS03605
uniprot id: I4D1X5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08170
gene id: 646529:DESACI_RS08170
uniprot id: I4D4I4
names: Similarity
messages: Belongs to the peptidase C40 family.

646529:DESACI RS20580
gene id: 646529:DESACI_RS20580
uniprot id: I4DBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

646529:DESACI RS04015
gene id: 646529:DESACI_RS04015
uniprot id: I4D254
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

646529:DESACI RS16995
gene id: 646529:DESACI_RS16995
uniprot id: I4D9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

646529:DESACI RS17835
gene id: 646529:DESACI_RS17835
uniprot id: I4D9Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

646529:DESACI RS22075
gene id: 646529:DESACI_RS22075
uniprot id: I4DCE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

646529:DESACI RS09050
gene id: 646529:DESACI_RS09050
uniprot id: I4D503
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS05490
gene id: 646529:DESACI_RS05490
uniprot id: I4D2Z7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS10115
gene id: 646529:DESACI_RS10115
uniprot id: I4D5L6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS03270
gene id: 646529:DESACI_RS03270
uniprot id: I4D1Q9
names: Subcellular Location Annotation
messages: Cytoplasm

646529:DESACI RS00375
gene id: 646529:DESACI_RS00375
uniprot id: I4D071
names: Similarity
messages: Belongs to the UPF0749 family.

646529:DESACI RS05540
gene id: 646529:DESACI_RS05540
uniprot id: I4D307
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS22070
gene id: 646529:DESACI_RS22070
uniprot id: I4DCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

646529:DESACI RS15175
gene id: 646529:DESACI_RS15175
uniprot id: I4D8G6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS17985
gene id: 646529:DESACI_RS17985
uniprot id: I4DA22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

646529:DESACI RS19080
gene id: 646529:DESACI_RS19080
uniprot id: I4DAP1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

646529:DESACI RS03680
gene id: 646529:DESACI_RS03680
uniprot id: I4D1Z1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

646529:DESACI RS07560
gene id: 646529:DESACI_RS07560
uniprot id: I4D461
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

646529:DESACI RS22165
gene id: 646529:DESACI_RS22165
uniprot id: I4DCF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

646529:DESACI RS09000
gene id: 646529:DESACI_RS09000
uniprot id: I4D4Z3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

646529:DESACI RS10830
gene id: 646529:DESACI_RS10830
uniprot id: I4D608
names: Similarity
messages: Belongs to the CvfB family.

646529:DESACI RS11015
gene id: 646529:DESACI_RS11015
uniprot id: I4D644
names: Similarity
messages: Belongs to the HdrA family.

646529:DESACI RS15235
gene id: 646529:DESACI_RS15235
uniprot id: I4D8H8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

646529:DESACI RS15645
gene id: 646529:DESACI_RS15645
uniprot id: I4D8Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

646529:DESACI RS13850
gene id: 646529:DESACI_RS13850
uniprot id: I4D7P6
names: Similarity
messages: Belongs to the histone deacetylase family.

646529:DESACI RS06080
gene id: 646529:DESACI_RS06080
uniprot id: I4D3B1
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13835
gene id: 646529:DESACI_RS13835
uniprot id: I4D7P3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

646529:DESACI RS15780
gene id: 646529:DESACI_RS15780
uniprot id: I4D8T3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

646529:DESACI RS20075
gene id: 646529:DESACI_RS20075
uniprot id: I4DB95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

646529:DESACI RS10075
gene id: 646529:DESACI_RS10075
uniprot id: I4D5K9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

646529:DESACI RS00275
gene id: 646529:DESACI_RS00275
uniprot id: I4D048
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

646529:DESACI RS04260
gene id: 646529:DESACI_RS04260
uniprot id: I4D2A6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiD family. UbiD-like/FDC subfamily.
messages: Binds 1 K(+) per subunit.
messages: Binds 1 Mn(2+) per subunit.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the prenyl-FMN-dependent decarboxylation of pyrrole-2-carboxylate (P2C). Can also catalyze the carboxylation of pyrrole in the presence of elevated concentrations of CO(2) or bicarbonate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS17505
gene id: 646529:DESACI_RS17505
uniprot id: I4D9S5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

646529:DESACI RS17050
gene id: 646529:DESACI_RS17050
uniprot id: I4D9I3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS03830
gene id: 646529:DESACI_RS03830
uniprot id: I4D220
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

646529:DESACI RS05455
gene id: 646529:DESACI_RS05455
uniprot id: I4D2Z0
names: Similarity
messages: Belongs to the peptidase S8 family.

646529:DESACI RS17275
gene id: 646529:DESACI_RS17275
uniprot id: I4D9M8
names: Similarity
messages: Belongs to the UPF0102 family.

646529:DESACI RS07035
gene id: 646529:DESACI_RS07035
uniprot id: I4D3W4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

646529:DESACI RS19485
gene id: 646529:DESACI_RS19485
uniprot id: I4DAX2
names: Similarity
messages: Belongs to the peptidase A24 family.

646529:DESACI RS04850
gene id: 646529:DESACI_RS04850
uniprot id: I4D2M1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

646529:DESACI RS02425
gene id: 646529:DESACI_RS02425
uniprot id: I4D188
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

646529:DESACI RS07965
gene id: 646529:DESACI_RS07965
uniprot id: I4D4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

646529:DESACI RS17390
gene id: 646529:DESACI_RS17390
uniprot id: I4D9Q2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS10915
gene id: 646529:DESACI_RS10915
uniprot id: I4D626
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

646529:DESACI RS06425
gene id: 646529:DESACI_RS06425
uniprot id: I4D3I8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

646529:DESACI RS07195
gene id: 646529:DESACI_RS07195
uniprot id: I4D3Z4
names: Similarity
messages: Belongs to the UPF0246 family.

646529:DESACI RS00665
gene id: 646529:DESACI_RS00665
uniprot id: I4D094
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

646529:DESACI RS05645
gene id: 646529:DESACI_RS05645
uniprot id: I4D327
names: Similarity
messages: Belongs to the leucine-binding protein family.

646529:DESACI RS02235
gene id: 646529:DESACI_RS02235
uniprot id: I4D151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS22225
gene id: 646529:DESACI_RS22225
uniprot id: I4DCH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

646529:DESACI RS08525
gene id: 646529:DESACI_RS08525
uniprot id: I4D4Q4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

646529:DESACI RS19085
gene id: 646529:DESACI_RS19085
uniprot id: I4DAP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

646529:DESACI RS17645
gene id: 646529:DESACI_RS17645
uniprot id: I4D9V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

646529:DESACI RS22065
gene id: 646529:DESACI_RS22065
uniprot id: I4DCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

646529:DESACI RS21270
gene id: 646529:DESACI_RS21270
uniprot id: I4DBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS06415
gene id: 646529:DESACI_RS06415
uniprot id: I4D3I6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

646529:DESACI RS15755
gene id: 646529:DESACI_RS15755
uniprot id: I4D8S8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

646529:DESACI RS10600
gene id: 646529:DESACI_RS10600
uniprot id: I4D5W5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS11710
gene id: 646529:DESACI_RS11710
uniprot id: I4D6I3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

646529:DESACI RS15030
gene id: 646529:DESACI_RS15030
uniprot id: I4D8D5
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

646529:DESACI RS15485
gene id: 646529:DESACI_RS15485
uniprot id: I4D8M5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS16770
gene id: 646529:DESACI_RS16770
uniprot id: I4D9C7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS05090
gene id: 646529:DESACI_RS05090
uniprot id: I4D2R7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

646529:DESACI RS16960
gene id: 646529:DESACI_RS16960
uniprot id: I4D9G5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS04485
gene id: 646529:DESACI_RS04485
uniprot id: I4D2E8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

646529:DESACI RS01345
gene id: 646529:DESACI_RS01345
uniprot id: I4D0M1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS05235
gene id: 646529:DESACI_RS05235
uniprot id: I4D2U6
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS18150
gene id: 646529:DESACI_RS18150
uniprot id: I4DA57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

646529:DESACI RS06460
gene id: 646529:DESACI_RS06460
uniprot id: I4D3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

646529:DESACI RS15695
gene id: 646529:DESACI_RS15695
uniprot id: I4D8R6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

646529:DESACI RS03155
gene id: 646529:DESACI_RS03155
uniprot id: I4D1N6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

646529:DESACI RS20905
gene id: 646529:DESACI_RS20905
uniprot id: I4DBQ7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS03450
gene id: 646529:DESACI_RS03450
uniprot id: I4D1U4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS03985
gene id: 646529:DESACI_RS03985
uniprot id: I4D248
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

646529:DESACI RS03440
gene id: 646529:DESACI_RS03440
uniprot id: I4D1U2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS02115
gene id: 646529:DESACI_RS02115
uniprot id: I4D125
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

646529:DESACI RS17530
gene id: 646529:DESACI_RS17530
uniprot id: I4D9T0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

646529:DESACI RS19045
gene id: 646529:DESACI_RS19045
uniprot id: I4DAN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

646529:DESACI RS11905
gene id: 646529:DESACI_RS11905
uniprot id: I4D6M2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

646529:DESACI RS02840
gene id: 646529:DESACI_RS02840
uniprot id: I4D1H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS15750
gene id: 646529:DESACI_RS15750
uniprot id: I4D8S7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

646529:DESACI RS17370
gene id: 646529:DESACI_RS17370
uniprot id: I4D9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

646529:DESACI RS02280
gene id: 646529:DESACI_RS02280
uniprot id: I4D160
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

646529:DESACI RS02595
gene id: 646529:DESACI_RS02595
uniprot id: I4D1C3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

646529:DESACI RS02385
gene id: 646529:DESACI_RS02385
uniprot id: I4D180
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

646529:DESACI RS19770
gene id: 646529:DESACI_RS19770
uniprot id: I4DB36
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

646529:DESACI RS10955
gene id: 646529:DESACI_RS10955
uniprot id: I4D634
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

646529:DESACI RS11425
gene id: 646529:DESACI_RS11425
uniprot id: I4D6C8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS12035
gene id: 646529:DESACI_RS12035
uniprot id: I4D6P7
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS21180
gene id: 646529:DESACI_RS21180
uniprot id: I4DBW1
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08960
gene id: 646529:DESACI_RS08960
uniprot id: I4D4Y5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

646529:DESACI RS09005
gene id: 646529:DESACI_RS09005
uniprot id: I4D4Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

646529:DESACI RS15075
gene id: 646529:DESACI_RS15075
uniprot id: I4D8E5
names: Similarity
messages: Belongs to the IMPACT family.

646529:DESACI RS03525
gene id: 646529:DESACI_RS03525
uniprot id: I4D1V9
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

646529:DESACI RS12465
gene id: 646529:DESACI_RS12465
uniprot id: I4D6X8
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS16655
gene id: 646529:DESACI_RS16655
uniprot id: I4D9A8
names: Similarity
messages: Belongs to the HypE family.

646529:DESACI RS15455
gene id: 646529:DESACI_RS15455
uniprot id: I4D8L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

646529:DESACI RS21375
gene id: 646529:DESACI_RS21375
uniprot id: I4DC01
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

646529:DESACI RS10890
gene id: 646529:DESACI_RS10890
uniprot id: I4D621
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

646529:DESACI RS00310
gene id: 646529:DESACI_RS00310
uniprot id: I4D056
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

646529:DESACI RS14990
gene id: 646529:DESACI_RS14990
uniprot id: I4D8C7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS19825
gene id: 646529:DESACI_RS19825
uniprot id: I4DB47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS21370
gene id: 646529:DESACI_RS21370
uniprot id: I4DC00
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS18040
gene id: 646529:DESACI_RS18040
uniprot id: I4DA35
names: Similarity
messages: Belongs to the UPF0342 family.

646529:DESACI RS13040
gene id: 646529:DESACI_RS13040
uniprot id: I4D795
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS15115
gene id: 646529:DESACI_RS15115
uniprot id: I4D8F4
names: Similarity
messages: Belongs to the asparaginase 1 family.

646529:DESACI RS03770
gene id: 646529:DESACI_RS03770
uniprot id: I4D209
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

646529:DESACI RS18390
gene id: 646529:DESACI_RS18390
uniprot id: I4DAA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

646529:DESACI RS17375
gene id: 646529:DESACI_RS17375
uniprot id: I4D9P8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

646529:DESACI RS05695
gene id: 646529:DESACI_RS05695
uniprot id: I4D336
names: Similarity
messages: Belongs to the proline racemase family.

646529:DESACI RS04515
gene id: 646529:DESACI_RS04515
uniprot id: I4D2F4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

646529:DESACI RS16090
gene id: 646529:DESACI_RS16090
uniprot id: I4D8Z4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

646529:DESACI RS16160
gene id: 646529:DESACI_RS16160
uniprot id: I4D909
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

646529:DESACI RS04165
gene id: 646529:DESACI_RS04165
uniprot id: I4D286
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS20210
gene id: 646529:DESACI_RS20210
uniprot id: I4DBC5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

646529:DESACI RS14595
gene id: 646529:DESACI_RS14595
uniprot id: I4D851
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS21110
gene id: 646529:DESACI_RS21110
uniprot id: I4DBU6
names: Similarity
messages: Belongs to the peptidase S8 family.

646529:DESACI RS22115
gene id: 646529:DESACI_RS22115
uniprot id: I4DCE9
names: Similarity
messages: Belongs to the UPF0340 family.

646529:DESACI RS00265
gene id: 646529:DESACI_RS00265
uniprot id: I4D046
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

646529:DESACI RS18085
gene id: 646529:DESACI_RS18085
uniprot id: I4DA44
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

646529:DESACI RS01045
gene id: 646529:DESACI_RS01045
uniprot id: I4D0G2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

646529:DESACI RS17310
gene id: 646529:DESACI_RS17310
uniprot id: I4D9N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

646529:DESACI RS05885
gene id: 646529:DESACI_RS05885
uniprot id: I4D373
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

646529:DESACI RS12195
gene id: 646529:DESACI_RS12195
uniprot id: I4D6S9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS18730
gene id: 646529:DESACI_RS18730
uniprot id: I4DAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS03100
gene id: 646529:DESACI_RS03100
uniprot id: I4D1M5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

646529:DESACI RS04245
gene id: 646529:DESACI_RS04245
uniprot id: I4D2A4
names: Similarity
messages: Belongs to the manganese catalase family.

646529:DESACI RS09800
gene id: 646529:DESACI_RS09800
uniprot id: I4D5F5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

646529:DESACI RS11630
gene id: 646529:DESACI_RS11630
uniprot id: I4D6H0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

646529:DESACI RS13200
gene id: 646529:DESACI_RS13200
uniprot id: I4D7C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

646529:DESACI RS11485
gene id: 646529:DESACI_RS11485
uniprot id: I4D6E3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

646529:DESACI RS15320
gene id: 646529:DESACI_RS15320
uniprot id: I4D8J5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

646529:DESACI RS07365
gene id: 646529:DESACI_RS07365
uniprot id: I4D423
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

646529:DESACI RS09070
gene id: 646529:DESACI_RS09070
uniprot id: I4D507
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

646529:DESACI RS10715
gene id: 646529:DESACI_RS10715
uniprot id: I4D5Y8
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

646529:DESACI RS15460
gene id: 646529:DESACI_RS15460
uniprot id: I4D8M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

646529:DESACI RS12520
gene id: 646529:DESACI_RS12520
uniprot id: I4D6Y9
names: Similarity
messages: Belongs to the HdrA family.

646529:DESACI RS21905
gene id: 646529:DESACI_RS21905
uniprot id: I4DCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

646529:DESACI RS13780
gene id: 646529:DESACI_RS13780
uniprot id: I4D7N3
names: Similarity
messages: Belongs to the peptidase S11 family.

646529:DESACI RS02785
gene id: 646529:DESACI_RS02785
uniprot id: I4D1F9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

646529:DESACI RS19905
gene id: 646529:DESACI_RS19905
uniprot id: I4DB63
names: Similarity
messages: Belongs to the asparagine synthetase family.

646529:DESACI RS10245
gene id: 646529:DESACI_RS10245
uniprot id: I4D5P3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS03395
gene id: 646529:DESACI_RS03395
uniprot id: I4D1T3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

646529:DESACI RS09860
gene id: 646529:DESACI_RS09860
uniprot id: I4D5G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

646529:DESACI RS13400
gene id: 646529:DESACI_RS13400
uniprot id: I4D7G4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

646529:DESACI RS20020
gene id: 646529:DESACI_RS20020
uniprot id: I4DB84
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS21765
gene id: 646529:DESACI_RS21765
uniprot id: I4DC81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

646529:DESACI RS03595
gene id: 646529:DESACI_RS03595
uniprot id: I4D1X3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS00730
gene id: 646529:DESACI_RS00730
uniprot id: I4D0A8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS21950
gene id: 646529:DESACI_RS21950
uniprot id: I4DCB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

646529:DESACI RS21480
gene id: 646529:DESACI_RS21480
uniprot id: I4DC20
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

646529:DESACI RS22045
gene id: 646529:DESACI_RS22045
uniprot id: I4DCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

646529:DESACI RS04670
gene id: 646529:DESACI_RS04670
uniprot id: I4D2I6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

646529:DESACI RS17860
gene id: 646529:DESACI_RS17860
uniprot id: I4D9Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

646529:DESACI RS02290
gene id: 646529:DESACI_RS02290
uniprot id: I4D162
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

646529:DESACI RS18285
gene id: 646529:DESACI_RS18285
uniprot id: I4DA84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

646529:DESACI RS12935
gene id: 646529:DESACI_RS12935
uniprot id: I4D773
names: Similarity
messages: Belongs to the leucine-binding protein family.

646529:DESACI RS02700
gene id: 646529:DESACI_RS02700
uniprot id: I4D1E3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

646529:DESACI RS22500
gene id: 646529:DESACI_RS22500
uniprot id: I4DCM4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS18445
gene id: 646529:DESACI_RS18445
uniprot id: I4DAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

646529:DESACI RS02560
gene id: 646529:DESACI_RS02560
uniprot id: I4D1B6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

646529:DESACI RS20730
gene id: 646529:DESACI_RS20730
uniprot id: I4DBM5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS22080
gene id: 646529:DESACI_RS22080
uniprot id: I4DCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

646529:DESACI RS11125
gene id: 646529:DESACI_RS11125
uniprot id: I4D668
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS07485
gene id: 646529:DESACI_RS07485
uniprot id: I4D446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

646529:DESACI RS11760
gene id: 646529:DESACI_RS11760
uniprot id: I4D6J3
names: Similarity
messages: Belongs to the glutamate synthase family.

646529:DESACI RS03705
gene id: 646529:DESACI_RS03705
uniprot id: I4D1Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS10795
gene id: 646529:DESACI_RS10795
uniprot id: I4D601
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

646529:DESACI RS05155
gene id: 646529:DESACI_RS05155
uniprot id: I4D2T0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

646529:DESACI RS18600
gene id: 646529:DESACI_RS18600
uniprot id: I4DAE8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

646529:DESACI RS12090
gene id: 646529:DESACI_RS12090
uniprot id: I4D6R0
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

646529:DESACI RS09045
gene id: 646529:DESACI_RS09045
uniprot id: I4D502
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS16990
gene id: 646529:DESACI_RS16990
uniprot id: I4D9H1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

646529:DESACI RS00850
gene id: 646529:DESACI_RS00850
uniprot id: I4D0C5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

646529:DESACI RS19125
gene id: 646529:DESACI_RS19125
uniprot id: I4DAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

646529:DESACI RS17015
gene id: 646529:DESACI_RS17015
uniprot id: I4D9H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

646529:DESACI RS02555
gene id: 646529:DESACI_RS02555
uniprot id: I4D1B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

646529:DESACI RS05655
gene id: 646529:DESACI_RS05655
uniprot id: I4D329
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS10850
gene id: 646529:DESACI_RS10850
uniprot id: I4D612
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS08390
gene id: 646529:DESACI_RS08390
uniprot id: I4D4M8
names: Similarity
messages: Belongs to the UPF0173 family.

646529:DESACI RS17690
gene id: 646529:DESACI_RS17690
uniprot id: I4D9W2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS01225
gene id: 646529:DESACI_RS01225
uniprot id: I4D0J6
names: Similarity
messages: Belongs to the citrate synthase family.

646529:DESACI RS13920
gene id: 646529:DESACI_RS13920
uniprot id: I4D7R1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

646529:DESACI RS09325
gene id: 646529:DESACI_RS09325
uniprot id: I4D560
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS12625
gene id: 646529:DESACI_RS12625
uniprot id: I4D711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

646529:DESACI RS11105
gene id: 646529:DESACI_RS11105
uniprot id: I4D664
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS17605
gene id: 646529:DESACI_RS17605
uniprot id: I4D9U5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

646529:DESACI RS17865
gene id: 646529:DESACI_RS17865
uniprot id: I4D9Z8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

646529:DESACI RS03975
gene id: 646529:DESACI_RS03975
uniprot id: I4D246
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

646529:DESACI RS08355
gene id: 646529:DESACI_RS08355
uniprot id: I4D4M0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

646529:DESACI RS21830
gene id: 646529:DESACI_RS21830
uniprot id: I4DC94
names: Similarity
messages: Belongs to the sigma-54 factor family.

646529:DESACI RS12360
gene id: 646529:DESACI_RS12360
uniprot id: I4D6V7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

646529:DESACI RS13165
gene id: 646529:DESACI_RS13165
uniprot id: I4D7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

646529:DESACI RS13220
gene id: 646529:DESACI_RS13220
uniprot id: I4D7C9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS16945
gene id: 646529:DESACI_RS16945
uniprot id: I4D9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

646529:DESACI RS18020
gene id: 646529:DESACI_RS18020
uniprot id: I4DA29
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

646529:DESACI RS03555
gene id: 646529:DESACI_RS03555
uniprot id: I4D1W5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

646529:DESACI RS17930
gene id: 646529:DESACI_RS17930
uniprot id: I4DA11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS22370
gene id: 646529:DESACI_RS22370
uniprot id: I4DCJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

646529:DESACI RS10870
gene id: 646529:DESACI_RS10870
uniprot id: I4D616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

646529:DESACI RS13330
gene id: 646529:DESACI_RS13330
uniprot id: I4D7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

646529:DESACI RS02400
gene id: 646529:DESACI_RS02400
uniprot id: I4D183
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

646529:DESACI RS17945
gene id: 646529:DESACI_RS17945
uniprot id: I4DA14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS16895
gene id: 646529:DESACI_RS16895
uniprot id: I4D9F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

646529:DESACI RS16135
gene id: 646529:DESACI_RS16135
uniprot id: I4D904
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

646529:DESACI RS04495
gene id: 646529:DESACI_RS04495
uniprot id: I4D2F0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

646529:DESACI RS21075
gene id: 646529:DESACI_RS21075
uniprot id: I4DBT9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS05845
gene id: 646529:DESACI_RS05845
uniprot id: I4D365
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

646529:DESACI RS10345
gene id: 646529:DESACI_RS10345
uniprot id: I4D5R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

646529:DESACI RS01135
gene id: 646529:DESACI_RS01135
uniprot id: I4D0I0
names: Similarity
messages: Belongs to the DinB family.

646529:DESACI RS20420
gene id: 646529:DESACI_RS20420
uniprot id: I4DBG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

646529:DESACI RS00715
gene id: 646529:DESACI_RS00715
uniprot id: I4D0A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

646529:DESACI RS11545
gene id: 646529:DESACI_RS11545
uniprot id: I4D6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

646529:DESACI RS15480
gene id: 646529:DESACI_RS15480
uniprot id: I4D8M4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

646529:DESACI RS12545
gene id: 646529:DESACI_RS12545
uniprot id: I4D6Z4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS09535
gene id: 646529:DESACI_RS09535
uniprot id: I4D598
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

646529:DESACI RS10990
gene id: 646529:DESACI_RS10990
uniprot id: I4D640
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

646529:DESACI RS21440
gene id: 646529:DESACI_RS21440
uniprot id: I4DC12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

646529:DESACI RS10040
gene id: 646529:DESACI_RS10040
uniprot id: I4D5K4
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

646529:DESACI RS05065
gene id: 646529:DESACI_RS05065
uniprot id: I4D2R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

646529:DESACI RS17615
gene id: 646529:DESACI_RS17615
uniprot id: I4D9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

646529:DESACI RS16255
gene id: 646529:DESACI_RS16255
uniprot id: I4D928
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

646529:DESACI RS03425
gene id: 646529:DESACI_RS03425
uniprot id: I4D1T9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS16610
gene id: 646529:DESACI_RS16610
uniprot id: I4D999
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

646529:DESACI RS01595
gene id: 646529:DESACI_RS01595
uniprot id: I4D0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

646529:DESACI RS22355
gene id: 646529:DESACI_RS22355
uniprot id: I4DCJ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

646529:DESACI RS00680
gene id: 646529:DESACI_RS00680
uniprot id: I4D097
names: Similarity
messages: Belongs to the class-I fumarase family.

646529:DESACI RS02495
gene id: 646529:DESACI_RS02495
uniprot id: I4D1A3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

646529:DESACI RS23160
gene id: 646529:DESACI_RS23160
uniprot id: I4D921
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS22505
gene id: 646529:DESACI_RS22505
uniprot id: I4DCM5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS15590
gene id: 646529:DESACI_RS15590
uniprot id: I4D8P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

646529:DESACI RS01885
gene id: 646529:DESACI_RS01885
uniprot id: I4D0X9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS16490
gene id: 646529:DESACI_RS16490
uniprot id: I4D973
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS21665
gene id: 646529:DESACI_RS21665
uniprot id: I4DC62
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS15915
gene id: 646529:DESACI_RS15915
uniprot id: I4D8W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

646529:DESACI RS03840
gene id: 646529:DESACI_RS03840
uniprot id: I4D222
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

646529:DESACI RS18935
gene id: 646529:DESACI_RS18935
uniprot id: I4DAL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

646529:DESACI RS07915
gene id: 646529:DESACI_RS07915
uniprot id: I4D4D1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

646529:DESACI RS17080
gene id: 646529:DESACI_RS17080
uniprot id: I4D9I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

646529:DESACI RS02475
gene id: 646529:DESACI_RS02475
uniprot id: I4D199
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

646529:DESACI RS06215
gene id: 646529:DESACI_RS06215
uniprot id: I4D3E3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

646529:DESACI RS20590
gene id: 646529:DESACI_RS20590
uniprot id: I4DBJ8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS01560
gene id: 646529:DESACI_RS01560
uniprot id: I4D0R6
names: Similarity
messages: Belongs to the HepT RNase toxin family.

646529:DESACI RS20495
gene id: 646529:DESACI_RS20495
uniprot id: I4DBI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

646529:DESACI RS07300
gene id: 646529:DESACI_RS07300
uniprot id: I4D414
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS12960
gene id: 646529:DESACI_RS12960
uniprot id: I4D778
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

646529:DESACI RS17005
gene id: 646529:DESACI_RS17005
uniprot id: I4D9H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

646529:DESACI RS08620
gene id: 646529:DESACI_RS08620
uniprot id: I4D4S4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

646529:DESACI RS22015
gene id: 646529:DESACI_RS22015
uniprot id: I4DCC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS07650
gene id: 646529:DESACI_RS07650
uniprot id: I4D480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

646529:DESACI RS14115
gene id: 646529:DESACI_RS14115
uniprot id: I4D7V2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS09125
gene id: 646529:DESACI_RS09125
uniprot id: I4D518
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

646529:DESACI RS12500
gene id: 646529:DESACI_RS12500
uniprot id: I4D6Y5
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

646529:DESACI RS02020
gene id: 646529:DESACI_RS02020
uniprot id: I4D106
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

646529:DESACI RS21195
gene id: 646529:DESACI_RS21195
uniprot id: I4DBW4
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS11840
gene id: 646529:DESACI_RS11840
uniprot id: I4D6K6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

646529:DESACI RS17315
gene id: 646529:DESACI_RS17315
uniprot id: I4D9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

646529:DESACI RS13505
gene id: 646529:DESACI_RS13505
uniprot id: I4D7H7
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13310
gene id: 646529:DESACI_RS13310
uniprot id: I4D7E8
names: Similarity
messages: Belongs to the peptidase C40 family.

646529:DESACI RS13180
gene id: 646529:DESACI_RS13180
uniprot id: I4D7C1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

646529:DESACI RS12720
gene id: 646529:DESACI_RS12720
uniprot id: I4D729
names: Subcellular Location Annotation
messages: Cytoplasm

646529:DESACI RS03130
gene id: 646529:DESACI_RS03130
uniprot id: I4D1N1
names: Similarity
messages: Belongs to the WrbA family.

646529:DESACI RS05480
gene id: 646529:DESACI_RS05480
uniprot id: I4D2Z5
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS05095
gene id: 646529:DESACI_RS05095
uniprot id: I4D2R8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS04100
gene id: 646529:DESACI_RS04100
uniprot id: I4D272
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

646529:DESACI RS17970
gene id: 646529:DESACI_RS17970
uniprot id: I4DA19
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS01825
gene id: 646529:DESACI_RS01825
uniprot id: I4D0W7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

646529:DESACI RS01025
gene id: 646529:DESACI_RS01025
uniprot id: I4D0F8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS02370
gene id: 646529:DESACI_RS02370
uniprot id: I4D177
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

646529:DESACI RS02800
gene id: 646529:DESACI_RS02800
uniprot id: I4D1G2
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS04230
gene id: 646529:DESACI_RS04230
uniprot id: I4D2A1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS17610
gene id: 646529:DESACI_RS17610
uniprot id: I4D9U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

646529:DESACI RS11990
gene id: 646529:DESACI_RS11990
uniprot id: I4D6N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

646529:DESACI RS03290
gene id: 646529:DESACI_RS03290
uniprot id: I4D1R3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS00030
gene id: 646529:DESACI_RS00030
uniprot id: I4D004
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

646529:DESACI RS06295
gene id: 646529:DESACI_RS06295
uniprot id: I4D3F9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

646529:DESACI RS01040
gene id: 646529:DESACI_RS01040
uniprot id: I4D0G1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS05350
gene id: 646529:DESACI_RS05350
uniprot id: I4D2X1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

646529:DESACI RS20165
gene id: 646529:DESACI_RS20165
uniprot id: I4DBB6
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS15945
gene id: 646529:DESACI_RS15945
uniprot id: I4D8W6
names: Similarity
messages: Belongs to the asp23 family.

646529:DESACI RS06395
gene id: 646529:DESACI_RS06395
uniprot id: I4D3I1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS00705
gene id: 646529:DESACI_RS00705
uniprot id: I4D0A2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS17340
gene id: 646529:DESACI_RS17340
uniprot id: I4D9P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

646529:DESACI RS17365
gene id: 646529:DESACI_RS17365
uniprot id: I4D9P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

646529:DESACI RS07420
gene id: 646529:DESACI_RS07420
uniprot id: I4D434
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS02175
gene id: 646529:DESACI_RS02175
uniprot id: I4D138
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS16810
gene id: 646529:DESACI_RS16810
uniprot id: I4D9D4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

646529:DESACI RS22100
gene id: 646529:DESACI_RS22100
uniprot id: I4DCE6
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

646529:DESACI RS20855
gene id: 646529:DESACI_RS20855
uniprot id: I4DBP7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

646529:DESACI RS04205
gene id: 646529:DESACI_RS04205
uniprot id: I4D296
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

646529:DESACI RS18430
gene id: 646529:DESACI_RS18430
uniprot id: I4DAB5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

646529:DESACI RS08765
gene id: 646529:DESACI_RS08765
uniprot id: I4D4U8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

646529:DESACI RS10530
gene id: 646529:DESACI_RS10530
uniprot id: I4D5V2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

646529:DESACI RS22035
gene id: 646529:DESACI_RS22035
uniprot id: I4DCD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS12780
gene id: 646529:DESACI_RS12780
uniprot id: I4D742
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS17600
gene id: 646529:DESACI_RS17600
uniprot id: I4D9U4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

646529:DESACI RS02590
gene id: 646529:DESACI_RS02590
uniprot id: I4D1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

646529:DESACI RS17760
gene id: 646529:DESACI_RS17760
uniprot id: I4D9X7
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

646529:DESACI RS11975
gene id: 646529:DESACI_RS11975
uniprot id: I4D6N5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

646529:DESACI RS10805
gene id: 646529:DESACI_RS10805
uniprot id: I4D603
names: Similarity
messages: Belongs to the glutamine synthetase family.

646529:DESACI RS03990
gene id: 646529:DESACI_RS03990
uniprot id: I4D249
names: Similarity
messages: Belongs to the CdaR family.

646529:DESACI RS17285
gene id: 646529:DESACI_RS17285
uniprot id: I4D9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

646529:DESACI RS12930
gene id: 646529:DESACI_RS12930
uniprot id: I4D772
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS03115
gene id: 646529:DESACI_RS03115
uniprot id: I4D1M8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

646529:DESACI RS00005
gene id: 646529:DESACI_RS00005
uniprot id: I4CZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

646529:DESACI RS21135
gene id: 646529:DESACI_RS21135
uniprot id: I4DBV2
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS19025
gene id: 646529:DESACI_RS19025
uniprot id: I4DAN0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

646529:DESACI RS17270
gene id: 646529:DESACI_RS17270
uniprot id: I4D9M7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS16890
gene id: 646529:DESACI_RS16890
uniprot id: I4D9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

646529:DESACI RS03710
gene id: 646529:DESACI_RS03710
uniprot id: I4D1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

646529:DESACI RS04210
gene id: 646529:DESACI_RS04210
uniprot id: I4D297
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

646529:DESACI RS07375
gene id: 646529:DESACI_RS07375
uniprot id: I4D425
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

646529:DESACI RS02340
gene id: 646529:DESACI_RS02340
uniprot id: I4D171
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

646529:DESACI RS17825
gene id: 646529:DESACI_RS17825
uniprot id: I4D9Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

646529:DESACI RS01350
gene id: 646529:DESACI_RS01350
uniprot id: I4D0M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

646529:DESACI RS17475
gene id: 646529:DESACI_RS17475
uniprot id: I4D9S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

646529:DESACI RS01485
gene id: 646529:DESACI_RS01485
uniprot id: I4D0P8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

646529:DESACI RS00040
gene id: 646529:DESACI_RS00040
uniprot id: I4D006
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

646529:DESACI RS17145
gene id: 646529:DESACI_RS17145
uniprot id: I4D9K2
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS19160
gene id: 646529:DESACI_RS19160
uniprot id: I4DAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

646529:DESACI RS02485
gene id: 646529:DESACI_RS02485
uniprot id: I4D1A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

646529:DESACI RS22435
gene id: 646529:DESACI_RS22435
uniprot id: I4DCL1
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13160
gene id: 646529:DESACI_RS13160
uniprot id: I4D7B7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

646529:DESACI RS02635
gene id: 646529:DESACI_RS02635
uniprot id: I4D1D1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

646529:DESACI RS09265
gene id: 646529:DESACI_RS09265
uniprot id: I4D547
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

646529:DESACI RS17070
gene id: 646529:DESACI_RS17070
uniprot id: I4D9I7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

646529:DESACI RS02120
gene id: 646529:DESACI_RS02120
uniprot id: I4D126
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

646529:DESACI RS11090
gene id: 646529:DESACI_RS11090
uniprot id: I4D660
names: Similarity
messages: Belongs to the universal stress protein A family.

646529:DESACI RS16665
gene id: 646529:DESACI_RS16665
uniprot id: I4D9B0
names: Similarity
messages: Belongs to the HupF/HypC family.

646529:DESACI RS19175
gene id: 646529:DESACI_RS19175
uniprot id: I4DAR1
names: Similarity
messages: Belongs to the NadC/ModD family.

646529:DESACI RS03750
gene id: 646529:DESACI_RS03750
uniprot id: I4D205
names: Similarity
messages: Belongs to the EamA transporter family.

646529:DESACI RS19795
gene id: 646529:DESACI_RS19795
uniprot id: I4DB41
names: Similarity
messages: Belongs to the GerABKA family.

646529:DESACI RS01480
gene id: 646529:DESACI_RS01480
uniprot id: I4D0P7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

646529:DESACI RS16540
gene id: 646529:DESACI_RS16540
uniprot id: I4D983
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

646529:DESACI RS23000
gene id: 646529:DESACI_RS23000
uniprot id: I4D3V2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

646529:DESACI RS08260
gene id: 646529:DESACI_RS08260
uniprot id: I4D4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

646529:DESACI RS00215
gene id: 646529:DESACI_RS00215
uniprot id: I4D036
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

646529:DESACI RS17235
gene id: 646529:DESACI_RS17235
uniprot id: I4D9M0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

646529:DESACI RS00975
gene id: 646529:DESACI_RS00975
uniprot id: I4D0E8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS00685
gene id: 646529:DESACI_RS00685
uniprot id: I4D098
names: Similarity
messages: Belongs to the class-I fumarase family.

646529:DESACI RS05025
gene id: 646529:DESACI_RS05025
uniprot id: I4D2Q4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

646529:DESACI RS07465
gene id: 646529:DESACI_RS07465
uniprot id: I4D442
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

646529:DESACI RS16545
gene id: 646529:DESACI_RS16545
uniprot id: I4D984
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

646529:DESACI RS08900
gene id: 646529:DESACI_RS08900
uniprot id: I4D4X3
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

646529:DESACI RS19985
gene id: 646529:DESACI_RS19985
uniprot id: I4DB78
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

646529:DESACI RS02295
gene id: 646529:DESACI_RS02295
uniprot id: I4D163
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

646529:DESACI RS18205
gene id: 646529:DESACI_RS18205
uniprot id: U3GJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

646529:DESACI RS13790
gene id: 646529:DESACI_RS13790
uniprot id: I4D7N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

646529:DESACI RS07490
gene id: 646529:DESACI_RS07490
uniprot id: I4D447
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

646529:DESACI RS00015
gene id: 646529:DESACI_RS00015
uniprot id: I4D001
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

646529:DESACI RS12750
gene id: 646529:DESACI_RS12750
uniprot id: I4D735
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

646529:DESACI RS00745
gene id: 646529:DESACI_RS00745
uniprot id: I4D0B1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

646529:DESACI RS15765
gene id: 646529:DESACI_RS15765
uniprot id: I4D8T0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

646529:DESACI RS19260
gene id: 646529:DESACI_RS19260
uniprot id: I4DAS8
names: Similarity
messages: Belongs to the P(II) protein family.

646529:DESACI RS16865
gene id: 646529:DESACI_RS16865
uniprot id: I4D9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

646529:DESACI RS16210
gene id: 646529:DESACI_RS16210
uniprot id: I4D919
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS22155
gene id: 646529:DESACI_RS22155
uniprot id: I4DCF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

646529:DESACI RS04175
gene id: 646529:DESACI_RS04175
uniprot id: I4D288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

646529:DESACI RS03315
gene id: 646529:DESACI_RS03315
uniprot id: I4D1R8
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS13935
gene id: 646529:DESACI_RS13935
uniprot id: I4D7R4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

646529:DESACI RS02095
gene id: 646529:DESACI_RS02095
uniprot id: I4D121
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

646529:DESACI RS16625
gene id: 646529:DESACI_RS16625
uniprot id: I4D9A2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

646529:DESACI RS09765
gene id: 646529:DESACI_RS09765
uniprot id: I4D5E8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

646529:DESACI RS00760
gene id: 646529:DESACI_RS00760
uniprot id: I4D0B4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

646529:DESACI RS00160
gene id: 646529:DESACI_RS00160
uniprot id: I4D025
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

646529:DESACI RS10835
gene id: 646529:DESACI_RS10835
uniprot id: I4D609
names: Similarity
messages: Belongs to the UPF0178 family.

646529:DESACI RS18560
gene id: 646529:DESACI_RS18560
uniprot id: I4DAE1
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS12410
gene id: 646529:DESACI_RS12410
uniprot id: I4D6W6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

646529:DESACI RS20415
gene id: 646529:DESACI_RS20415
uniprot id: I4DBG4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

646529:DESACI RS01450
gene id: 646529:DESACI_RS01450
uniprot id: I4D0P1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

646529:DESACI RS21815
gene id: 646529:DESACI_RS21815
uniprot id: I4DC91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

646529:DESACI RS09855
gene id: 646529:DESACI_RS09855
uniprot id: I4D5G6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

646529:DESACI RS14810
gene id: 646529:DESACI_RS14810
uniprot id: I4D893
names: Similarity
messages: Belongs to the thymidylate kinase family.

646529:DESACI RS07670
gene id: 646529:DESACI_RS07670
uniprot id: I4D484
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

646529:DESACI RS10760
gene id: 646529:DESACI_RS10760
uniprot id: I4D5Z4
names: Similarity
messages: Belongs to the peptidase C40 family.

646529:DESACI RS21505
gene id: 646529:DESACI_RS21505
uniprot id: I4DC26
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS12140
gene id: 646529:DESACI_RS12140
uniprot id: I4D6S0
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS04490
gene id: 646529:DESACI_RS04490
uniprot id: I4D2E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

646529:DESACI RS11165
gene id: 646529:DESACI_RS11165
uniprot id: I4D676
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

646529:DESACI RS12615
gene id: 646529:DESACI_RS12615
uniprot id: I4D709
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

646529:DESACI RS10995
gene id: 646529:DESACI_RS10995
uniprot id: I4D641
names: Subcellular Location Annotation
messages: Membrane

646529:DESACI RS11985
gene id: 646529:DESACI_RS11985
uniprot id: I4D6N7
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

646529:DESACI RS12905
gene id: 646529:DESACI_RS12905
uniprot id: I4D766
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

646529:DESACI RS02350
gene id: 646529:DESACI_RS02350
uniprot id: I4D173
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

646529:DESACI RS02600
gene id: 646529:DESACI_RS02600
uniprot id: I4D1C4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

646529:DESACI RS12400
gene id: 646529:DESACI_RS12400
uniprot id: I4D6W4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

646529:DESACI RS03370
gene id: 646529:DESACI_RS03370
uniprot id: I4D1S9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

646529:DESACI RS18820
gene id: 646529:DESACI_RS18820
uniprot id: I4DAJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

646529:DESACI RS18450
gene id: 646529:DESACI_RS18450
uniprot id: I4DAB9
names: Similarity
messages: Belongs to the MotB family.

646529:DESACI RS00660
gene id: 646529:DESACI_RS00660
uniprot id: I4D093
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

646529:DESACI RS03950
gene id: 646529:DESACI_RS03950
uniprot id: I4D241
names: Similarity
messages: Belongs to the band 7/mec-2 family.

646529:DESACI RS11020
gene id: 646529:DESACI_RS11020
uniprot id: I4D645
names: Similarity
messages: Belongs to the HdrA family.

646529:DESACI RS17895
gene id: 646529:DESACI_RS17895
uniprot id: I4DA04
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

646529:DESACI RS17350
gene id: 646529:DESACI_RS17350
uniprot id: I4D9P3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

646529:DESACI RS18385
gene id: 646529:DESACI_RS18385
uniprot id: U3GJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

646529:DESACI RS19050
gene id: 646529:DESACI_RS19050
uniprot id: I4DAN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

646529:DESACI RS20975
gene id: 646529:DESACI_RS20975
uniprot id: I4DBS0
names: Similarity
messages: Belongs to the peptidase S41A family.

646529:DESACI RS21120
gene id: 646529:DESACI_RS21120
uniprot id: I4DBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

646529:DESACI RS15710
gene id: 646529:DESACI_RS15710
uniprot id: I4D8R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

646529:DESACI RS03405
gene id: 646529:DESACI_RS03405
uniprot id: I4D1T5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

646529:DESACI RS20760
gene id: 646529:DESACI_RS20760
uniprot id: I4DBM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

646529:DESACI RS16685
gene id: 646529:DESACI_RS16685
uniprot id: I4D9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

646529:DESACI RS17000
gene id: 646529:DESACI_RS17000
uniprot id: I4D9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm