645991:SGLY RS09155
gene id: 645991:SGLY_RS09155
uniprot id: F0T051
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

645991:SGLY RS01320
gene id: 645991:SGLY_RS01320
uniprot id: F0SWS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

645991:SGLY RS15265
gene id: 645991:SGLY_RS15265
uniprot id: F0T0E2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

645991:SGLY RS02280
gene id: 645991:SGLY_RS02280
uniprot id: F0SY54
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS12945
gene id: 645991:SGLY_RS12945
uniprot id: F0SWL4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS07190
gene id: 645991:SGLY_RS07190
uniprot id: F0SWH4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645991:SGLY RS13780
gene id: 645991:SGLY_RS13780
uniprot id: F0SXV7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS00795
gene id: 645991:SGLY_RS00795
uniprot id: F0SVQ2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

645991:SGLY RS11770
gene id: 645991:SGLY_RS11770
uniprot id: F0SUR8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

645991:SGLY RS11425
gene id: 645991:SGLY_RS11425
uniprot id: F0SUB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

645991:SGLY RS10690
gene id: 645991:SGLY_RS10690
uniprot id: F0T2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

645991:SGLY RS07365
gene id: 645991:SGLY_RS07365
uniprot id: F0SWZ2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS12815
gene id: 645991:SGLY_RS12815
uniprot id: F0SW46
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS07050
gene id: 645991:SGLY_RS07050
uniprot id: F0SWE7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

645991:SGLY RS11975
gene id: 645991:SGLY_RS11975
uniprot id: F0SUV8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

645991:SGLY RS12910
gene id: 645991:SGLY_RS12910
uniprot id: F0SWK9
names: Similarity
messages: Belongs to the AAA ATPase family.

645991:SGLY RS09845
gene id: 645991:SGLY_RS09845
uniprot id: F0SYM3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

645991:SGLY RS07490
gene id: 645991:SGLY_RS07490
uniprot id: F0SX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS00980
gene id: 645991:SGLY_RS00980
uniprot id: F0SW78
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

645991:SGLY RS15205
gene id: 645991:SGLY_RS15205
uniprot id: F0T0D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

645991:SGLY RS13605
gene id: 645991:SGLY_RS13605
uniprot id: F0SXS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS01275
gene id: 645991:SGLY_RS01275
uniprot id: F0SWR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

645991:SGLY RS10725
gene id: 645991:SGLY_RS10725
uniprot id: F0T2P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

645991:SGLY RS02435
gene id: 645991:SGLY_RS02435
uniprot id: F0SYN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

645991:SGLY RS11135
gene id: 645991:SGLY_RS11135
uniprot id: F0STZ6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS12300
gene id: 645991:SGLY_RS12300
uniprot id: F0SVG1
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS11530
gene id: 645991:SGLY_RS11530
uniprot id: F0SUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

645991:SGLY RS14290
gene id: 645991:SGLY_RS14290
uniprot id: F0SYK6
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

645991:SGLY RS14095
gene id: 645991:SGLY_RS14095
uniprot id: F0SYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

645991:SGLY RS02050
gene id: 645991:SGLY_RS02050
uniprot id: F0SY07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

645991:SGLY RS16575
gene id: 645991:SGLY_RS16575
uniprot id: F0T2U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

645991:SGLY RS16485
gene id: 645991:SGLY_RS16485
uniprot id: F0T2D1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS06650
gene id: 645991:SGLY_RS06650
uniprot id: F0SVT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

645991:SGLY RS13480
gene id: 645991:SGLY_RS13480
uniprot id: F0SX98
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

645991:SGLY RS08670
gene id: 645991:SGLY_RS08670
uniprot id: F0SZ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

645991:SGLY RS04610
gene id: 645991:SGLY_RS04610
uniprot id: F0T1Z3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

645991:SGLY RS12255
gene id: 645991:SGLY_RS12255
uniprot id: F0SVF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

645991:SGLY RS04970
gene id: 645991:SGLY_RS04970
uniprot id: F0T2K5
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16810
gene id: 645991:SGLY_RS16810
uniprot id: F0T2Y3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

645991:SGLY RS07430
gene id: 645991:SGLY_RS07430
uniprot id: F0SX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

645991:SGLY RS01550
gene id: 645991:SGLY_RS01550
uniprot id: F0SWW8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

645991:SGLY RS12160
gene id: 645991:SGLY_RS12160
uniprot id: F0SVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

645991:SGLY RS00035
gene id: 645991:SGLY_RS00035
uniprot id: F0SUH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

645991:SGLY RS13515
gene id: 645991:SGLY_RS13515
uniprot id: F0SXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

645991:SGLY RS11615
gene id: 645991:SGLY_RS11615
uniprot id: F0SUF1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

645991:SGLY RS12035
gene id: 645991:SGLY_RS12035
uniprot id: F0SUW9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

645991:SGLY RS00820
gene id: 645991:SGLY_RS00820
uniprot id: F0SVQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

645991:SGLY RS05105
gene id: 645991:SGLY_RS05105
uniprot id: F0STQ5
names: Similarity
messages: Belongs to the polypeptide deformylase family.

645991:SGLY RS06935
gene id: 645991:SGLY_RS06935
uniprot id: F0SWC6
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

645991:SGLY RS07705
gene id: 645991:SGLY_RS07705
uniprot id: F0SXL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

645991:SGLY RS03225
gene id: 645991:SGLY_RS03225
uniprot id: F0SZX7
names: Similarity
messages: Belongs to the MecA family.

645991:SGLY RS12535
gene id: 645991:SGLY_RS12535
uniprot id: F0SVZ6
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS04255
gene id: 645991:SGLY_RS04255
uniprot id: F0T1S6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

645991:SGLY RS11585
gene id: 645991:SGLY_RS11585
uniprot id: F0SUE5
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

645991:SGLY RS15995
gene id: 645991:SGLY_RS15995
uniprot id: F0T1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS01980
gene id: 645991:SGLY_RS01980
uniprot id: F0SXZ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

645991:SGLY RS01380
gene id: 645991:SGLY_RS01380
uniprot id: F0SWU0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS12430
gene id: 645991:SGLY_RS12430
uniprot id: F0SVI7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

645991:SGLY RS05775
gene id: 645991:SGLY_RS05775
uniprot id: F0SU86
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS12005
gene id: 645991:SGLY_RS12005
uniprot id: F0SUW4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

645991:SGLY RS14410
gene id: 645991:SGLY_RS14410
uniprot id: F0SZ23
names: Similarity
messages: Belongs to the TrpC family.

645991:SGLY RS02155
gene id: 645991:SGLY_RS02155
uniprot id: F0SY28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

645991:SGLY RS00130
gene id: 645991:SGLY_RS00130
uniprot id: F0SUX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

645991:SGLY RS12070
gene id: 645991:SGLY_RS12070
uniprot id: F0SVB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS01435
gene id: 645991:SGLY_RS01435
uniprot id: F0SWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

645991:SGLY RS15025
gene id: 645991:SGLY_RS15025
uniprot id: F0SZU5
names: Similarity
messages: Belongs to the peptidase S8 family.

645991:SGLY RS10280
gene id: 645991:SGLY_RS10280
uniprot id: F0T214
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

645991:SGLY RS16845
gene id: 645991:SGLY_RS16845
uniprot id: F0T2Z0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS10765
gene id: 645991:SGLY_RS10765
uniprot id: F0T2Q1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

645991:SGLY RS08430
gene id: 645991:SGLY_RS08430
uniprot id: F0SYV5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

645991:SGLY RS02045
gene id: 645991:SGLY_RS02045
uniprot id: F0SY06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

645991:SGLY RS11890
gene id: 645991:SGLY_RS11890
uniprot id: F0SUU2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

645991:SGLY RS09270
gene id: 645991:SGLY_RS09270
uniprot id: F0T073
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

645991:SGLY RS02405
gene id: 645991:SGLY_RS02405
uniprot id: F0SYM6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

645991:SGLY RS10915
gene id: 645991:SGLY_RS10915
uniprot id: F0T2T0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

645991:SGLY RS17030
gene id: 645991:SGLY_RS17030
uniprot id: F0SU41
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

645991:SGLY RS03330
gene id: 645991:SGLY_RS03330
uniprot id: F0SZZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS09280
gene id: 645991:SGLY_RS09280
uniprot id: F0T075
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

645991:SGLY RS10215
gene id: 645991:SGLY_RS10215
uniprot id: F0T201
names: Similarity
messages: Belongs to the HupF/HypC family.

645991:SGLY RS09400
gene id: 645991:SGLY_RS09400
uniprot id: F0T099
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

645991:SGLY RS14705
gene id: 645991:SGLY_RS14705
uniprot id: F0SZ82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

645991:SGLY RS10800
gene id: 645991:SGLY_RS10800
uniprot id: F0T2Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

645991:SGLY RS06170
gene id: 645991:SGLY_RS06170
uniprot id: F0SUQ1
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS01075
gene id: 645991:SGLY_RS01075
uniprot id: F0SW98
names: Similarity
messages: Belongs to the UPF0749 family.

645991:SGLY RS00915
gene id: 645991:SGLY_RS00915
uniprot id: F0SW66
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

645991:SGLY RS14445
gene id: 645991:SGLY_RS14445
uniprot id: F0SZ30
names: Similarity
messages: Belongs to the CobH/CbiC family.

645991:SGLY RS16755
gene id: 645991:SGLY_RS16755
uniprot id: F0T2X2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

645991:SGLY RS16370
gene id: 645991:SGLY_RS16370
uniprot id: F0T2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

645991:SGLY RS03555
gene id: 645991:SGLY_RS03555
uniprot id: F0T0J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

645991:SGLY RS11980
gene id: 645991:SGLY_RS11980
uniprot id: F0SUV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

645991:SGLY RS03725
gene id: 645991:SGLY_RS03725
uniprot id: F0T0M5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

645991:SGLY RS09010
gene id: 645991:SGLY_RS09010
uniprot id: F0SZM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

645991:SGLY RS03380
gene id: 645991:SGLY_RS03380
uniprot id: F0T009
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

645991:SGLY RS16515
gene id: 645991:SGLY_RS16515
uniprot id: F0T2D7
names: Similarity
messages: Belongs to the SleB family.

645991:SGLY RS03100
gene id: 645991:SGLY_RS03100
uniprot id: F0SZF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

645991:SGLY RS08290
gene id: 645991:SGLY_RS08290
uniprot id: F0SYC8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS11450
gene id: 645991:SGLY_RS11450
uniprot id: F0SUB8
names: Similarity
messages: Belongs to the peptidase C40 family.

645991:SGLY RS14375
gene id: 645991:SGLY_RS14375
uniprot id: F0SZ17
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

645991:SGLY RS08585
gene id: 645991:SGLY_RS08585
uniprot id: F0SYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS05875
gene id: 645991:SGLY_RS05875
uniprot id: F0SUJ5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

645991:SGLY RS13655
gene id: 645991:SGLY_RS13655
uniprot id: F0SXT3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

645991:SGLY RS09960
gene id: 645991:SGLY_RS09960
uniprot id: F0T1F3
names: Similarity
messages: Belongs to the UPF0145 family.

645991:SGLY RS03310
gene id: 645991:SGLY_RS03310
uniprot id: F0SZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

645991:SGLY RS06095
gene id: 645991:SGLY_RS06095
uniprot id: F0SUN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

645991:SGLY RS02010
gene id: 645991:SGLY_RS02010
uniprot id: F0SXZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

645991:SGLY RS02325
gene id: 645991:SGLY_RS02325
uniprot id: F0SY63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

645991:SGLY RS07945
gene id: 645991:SGLY_RS07945
uniprot id: F0SXR0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

645991:SGLY RS02685
gene id: 645991:SGLY_RS02685
uniprot id: F0SYT1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

645991:SGLY RS03445
gene id: 645991:SGLY_RS03445
uniprot id: F0T022
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

645991:SGLY RS12150
gene id: 645991:SGLY_RS12150
uniprot id: F0SVD1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

645991:SGLY RS13495
gene id: 645991:SGLY_RS13495
uniprot id: F0SXA1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

645991:SGLY RS02145
gene id: 645991:SGLY_RS02145
uniprot id: F0SY26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

645991:SGLY RS08795
gene id: 645991:SGLY_RS08795
uniprot id: F0SZI0
names: Similarity
messages: Belongs to the histone deacetylase family.

645991:SGLY RS02255
gene id: 645991:SGLY_RS02255
uniprot id: F0SY49
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

645991:SGLY RS08145
gene id: 645991:SGLY_RS08145
uniprot id: F0SY99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS16245
gene id: 645991:SGLY_RS16245
uniprot id: F0T283
names: Similarity
messages: Belongs to the peptidase S41A family.

645991:SGLY RS10475
gene id: 645991:SGLY_RS10475
uniprot id: F0T253
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS08805
gene id: 645991:SGLY_RS08805
uniprot id: F0SZI2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

645991:SGLY RS06975
gene id: 645991:SGLY_RS06975
uniprot id: F0SWD3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS02120
gene id: 645991:SGLY_RS02120
uniprot id: F0SY21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

645991:SGLY RS06405
gene id: 645991:SGLY_RS06405
uniprot id: F0SV88
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

645991:SGLY RS01570
gene id: 645991:SGLY_RS01570
uniprot id: F0SWX2
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS11700
gene id: 645991:SGLY_RS11700
uniprot id: F0SUQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS12555
gene id: 645991:SGLY_RS12555
uniprot id: F0SVZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

645991:SGLY RS12145
gene id: 645991:SGLY_RS12145
uniprot id: F0SVD0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645991:SGLY RS03105
gene id: 645991:SGLY_RS03105
uniprot id: F0SZG0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

645991:SGLY RS06040
gene id: 645991:SGLY_RS06040
uniprot id: F0SUM7
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS01360
gene id: 645991:SGLY_RS01360
uniprot id: F0SWT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

645991:SGLY RS14035
gene id: 645991:SGLY_RS14035
uniprot id: F0SYF4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

645991:SGLY RS13970
gene id: 645991:SGLY_RS13970
uniprot id: F0SYE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

645991:SGLY RS05470
gene id: 645991:SGLY_RS05470
uniprot id: F0SU28
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS01430
gene id: 645991:SGLY_RS01430
uniprot id: F0SWU5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

645991:SGLY RS14235
gene id: 645991:SGLY_RS14235
uniprot id: F0SYJ4
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

645991:SGLY RS07640
gene id: 645991:SGLY_RS07640
uniprot id: F0SXJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

645991:SGLY RS13615
gene id: 645991:SGLY_RS13615
uniprot id: F0SXS4
names: Similarity
messages: Belongs to the glutamine synthetase family.

645991:SGLY RS09165
gene id: 645991:SGLY_RS09165
uniprot id: F0T053
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

645991:SGLY RS15590
gene id: 645991:SGLY_RS15590
uniprot id: F0T106
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

645991:SGLY RS15190
gene id: 645991:SGLY_RS15190
uniprot id: F0T0C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

645991:SGLY RS02185
gene id: 645991:SGLY_RS02185
uniprot id: F0SY35
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

645991:SGLY RS05725
gene id: 645991:SGLY_RS05725
uniprot id: F0SU78
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

645991:SGLY RS12260
gene id: 645991:SGLY_RS12260
uniprot id: F0SVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

645991:SGLY RS00015
gene id: 645991:SGLY_RS00015
uniprot id: F0SUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

645991:SGLY RS06925
gene id: 645991:SGLY_RS06925
uniprot id: F0SWC4
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

645991:SGLY RS14510
gene id: 645991:SGLY_RS14510
uniprot id: F0SZ43
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

645991:SGLY RS16585
gene id: 645991:SGLY_RS16585
uniprot id: F0T2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

645991:SGLY RS12420
gene id: 645991:SGLY_RS12420
uniprot id: F0SVI5
names: Similarity
messages: Belongs to the UPF0758 family.

645991:SGLY RS11280
gene id: 645991:SGLY_RS11280
uniprot id: F0SU11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

645991:SGLY RS02600
gene id: 645991:SGLY_RS02600
uniprot id: F0SYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

645991:SGLY RS08415
gene id: 645991:SGLY_RS08415
uniprot id: F0SYV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

645991:SGLY RS12360
gene id: 645991:SGLY_RS12360
uniprot id: F0SVH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

645991:SGLY RS14650
gene id: 645991:SGLY_RS14650
uniprot id: F0SZ71
names: Similarity
messages: Belongs to the Nudix hydrolase family.

645991:SGLY RS14640
gene id: 645991:SGLY_RS14640
uniprot id: F0SZ69
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS03585
gene id: 645991:SGLY_RS03585
uniprot id: F0T0J7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

645991:SGLY RS11430
gene id: 645991:SGLY_RS11430
uniprot id: F0SUB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

645991:SGLY RS07425
gene id: 645991:SGLY_RS07425
uniprot id: F0SX04
names: Similarity
messages: Belongs to the bacterial solute-binding protein 8 family.

645991:SGLY RS02175
gene id: 645991:SGLY_RS02175
uniprot id: F0SY33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

645991:SGLY RS10820
gene id: 645991:SGLY_RS10820
uniprot id: F0T2R1
names: Similarity
messages: Belongs to the IMPACT family.

645991:SGLY RS14485
gene id: 645991:SGLY_RS14485
uniprot id: F0SZ38
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS11120
gene id: 645991:SGLY_RS11120
uniprot id: F0STZ3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS03640
gene id: 645991:SGLY_RS03640
uniprot id: F0T0K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

645991:SGLY RS02365
gene id: 645991:SGLY_RS02365
uniprot id: F0SYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS11850
gene id: 645991:SGLY_RS11850
uniprot id: F0SUT4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

645991:SGLY RS11925
gene id: 645991:SGLY_RS11925
uniprot id: F0SUU8
names: Similarity
messages: Belongs to the SleB family.

645991:SGLY RS09590
gene id: 645991:SGLY_RS09590
uniprot id: F0T0T5
names: Similarity
messages: Belongs to the GSP E family.

645991:SGLY RS03680
gene id: 645991:SGLY_RS03680
uniprot id: F0T0L6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

645991:SGLY RS10250
gene id: 645991:SGLY_RS10250
uniprot id: F0T208
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS13010
gene id: 645991:SGLY_RS13010
uniprot id: F0SWM7
names: Similarity
messages: Belongs to the peptidase S41A family.

645991:SGLY RS16355
gene id: 645991:SGLY_RS16355
uniprot id: F0T2A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

645991:SGLY RS12125
gene id: 645991:SGLY_RS12125
uniprot id: F0SVC6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

645991:SGLY RS00030
gene id: 645991:SGLY_RS00030
uniprot id: F0SUH4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

645991:SGLY RS16770
gene id: 645991:SGLY_RS16770
uniprot id: F0T2X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

645991:SGLY RS14115
gene id: 645991:SGLY_RS14115
uniprot id: F0SYG9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645991:SGLY RS08650
gene id: 645991:SGLY_RS08650
uniprot id: F0SYZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS13580
gene id: 645991:SGLY_RS13580
uniprot id: F0SXB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

645991:SGLY RS12755
gene id: 645991:SGLY_RS12755
uniprot id: F0SW37
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

645991:SGLY RS12295
gene id: 645991:SGLY_RS12295
uniprot id: F0SVG0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

645991:SGLY RS03170
gene id: 645991:SGLY_RS03170
uniprot id: F0SZW7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

645991:SGLY RS04120
gene id: 645991:SGLY_RS04120
uniprot id: F0T198
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

645991:SGLY RS02235
gene id: 645991:SGLY_RS02235
uniprot id: F0SY45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

645991:SGLY RS11570
gene id: 645991:SGLY_RS11570
uniprot id: F0SUE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

645991:SGLY RS06890
gene id: 645991:SGLY_RS06890
uniprot id: F0SVX7
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

645991:SGLY RS08855
gene id: 645991:SGLY_RS08855
uniprot id: F0SZJ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

645991:SGLY RS12175
gene id: 645991:SGLY_RS12175
uniprot id: F0SVD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

645991:SGLY RS11095
gene id: 645991:SGLY_RS11095
uniprot id: F0STY8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

645991:SGLY RS10005
gene id: 645991:SGLY_RS10005
uniprot id: F0T1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

645991:SGLY RS10355
gene id: 645991:SGLY_RS10355
uniprot id: F0T229
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS08575
gene id: 645991:SGLY_RS08575
uniprot id: F0SYY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS16460
gene id: 645991:SGLY_RS16460
uniprot id: F0T2C6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

645991:SGLY RS03440
gene id: 645991:SGLY_RS03440
uniprot id: F0T021
names: Similarity
messages: Belongs to the ComB family.

645991:SGLY RS16225
gene id: 645991:SGLY_RS16225
uniprot id: F0T279
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

645991:SGLY RS09235
gene id: 645991:SGLY_RS09235
uniprot id: F0T066
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

645991:SGLY RS03560
gene id: 645991:SGLY_RS03560
uniprot id: F0T0J1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS11750
gene id: 645991:SGLY_RS11750
uniprot id: F0SUR4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

645991:SGLY RS02060
gene id: 645991:SGLY_RS02060
uniprot id: F0SY09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

645991:SGLY RS16430
gene id: 645991:SGLY_RS16430
uniprot id: F0T2C0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

645991:SGLY RS03145
gene id: 645991:SGLY_RS03145
uniprot id: F0SZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

645991:SGLY RS02030
gene id: 645991:SGLY_RS02030
uniprot id: F0SY03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

645991:SGLY RS15090
gene id: 645991:SGLY_RS15090
uniprot id: F0T0A7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

645991:SGLY RS15320
gene id: 645991:SGLY_RS15320
uniprot id: F0T0F2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS01105
gene id: 645991:SGLY_RS01105
uniprot id: F0SWA4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

645991:SGLY RS12385
gene id: 645991:SGLY_RS12385
uniprot id: F0SVH8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS10520
gene id: 645991:SGLY_RS10520
uniprot id: F0T262
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

645991:SGLY RS08750
gene id: 645991:SGLY_RS08750
uniprot id: F0SZH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

645991:SGLY RS10795
gene id: 645991:SGLY_RS10795
uniprot id: F0T2Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

645991:SGLY RS09665
gene id: 645991:SGLY_RS09665
uniprot id: F0T0V0
names: Similarity
messages: Belongs to the UPF0473 family.

645991:SGLY RS16075
gene id: 645991:SGLY_RS16075
uniprot id: F0T1Q1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

645991:SGLY RS14625
gene id: 645991:SGLY_RS14625
uniprot id: F0SZ66
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

645991:SGLY RS16570
gene id: 645991:SGLY_RS16570
uniprot id: F0T2T9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

645991:SGLY RS03370
gene id: 645991:SGLY_RS03370
uniprot id: F0T007
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

645991:SGLY RS11685
gene id: 645991:SGLY_RS11685
uniprot id: F0SUG6
names: Similarity
messages: Belongs to the asp23 family.

645991:SGLY RS10735
gene id: 645991:SGLY_RS10735
uniprot id: F0T2P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

645991:SGLY RS03245
gene id: 645991:SGLY_RS03245
uniprot id: F0SZY1
names: Similarity
messages: Belongs to the peptidase U62 family.

645991:SGLY RS08215
gene id: 645991:SGLY_RS08215
uniprot id: F0SYB3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

645991:SGLY RS07650
gene id: 645991:SGLY_RS07650
uniprot id: F0SXK1
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS13695
gene id: 645991:SGLY_RS13695
uniprot id: F0SXU0
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

645991:SGLY RS15605
gene id: 645991:SGLY_RS15605
uniprot id: F0T109
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

645991:SGLY RS08875
gene id: 645991:SGLY_RS08875
uniprot id: F0SZJ7
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS02315
gene id: 645991:SGLY_RS02315
uniprot id: F0SY61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

645991:SGLY RS11965
gene id: 645991:SGLY_RS11965
uniprot id: F0SUV6
names: Similarity
messages: Belongs to the ThiD family.

645991:SGLY RS14450
gene id: 645991:SGLY_RS14450
uniprot id: F0SZ31
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

645991:SGLY RS07250
gene id: 645991:SGLY_RS07250
uniprot id: F0SWI7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

645991:SGLY RS08300
gene id: 645991:SGLY_RS08300
uniprot id: F0SYD1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

645991:SGLY RS11575
gene id: 645991:SGLY_RS11575
uniprot id: F0SUE3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

645991:SGLY RS05530
gene id: 645991:SGLY_RS05530
uniprot id: F0SU40
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS02085
gene id: 645991:SGLY_RS02085
uniprot id: F0SY14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

645991:SGLY RS08955
gene id: 645991:SGLY_RS08955
uniprot id: F0SZL2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

645991:SGLY RS03340
gene id: 645991:SGLY_RS03340
uniprot id: F0T001
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS11230
gene id: 645991:SGLY_RS11230
uniprot id: F0SU01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS07520
gene id: 645991:SGLY_RS07520
uniprot id: F0SX23
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS05720
gene id: 645991:SGLY_RS05720
uniprot id: F0SU77
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

645991:SGLY RS03035
gene id: 645991:SGLY_RS03035
uniprot id: F0SZE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

645991:SGLY RS09680
gene id: 645991:SGLY_RS09680
uniprot id: F0T0V3
names: Similarity
messages: Belongs to the UPF0297 family.

645991:SGLY RS12235
gene id: 645991:SGLY_RS12235
uniprot id: F0SVE8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

645991:SGLY RS09275
gene id: 645991:SGLY_RS09275
uniprot id: F0T074
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

645991:SGLY RS12450
gene id: 645991:SGLY_RS12450
uniprot id: F0SVY0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

645991:SGLY RS08865
gene id: 645991:SGLY_RS08865
uniprot id: F0SZJ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

645991:SGLY RS06820
gene id: 645991:SGLY_RS06820
uniprot id: F0SVW3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS00215
gene id: 645991:SGLY_RS00215
uniprot id: F0SUZ4
names: Similarity
messages: Belongs to the peptidase C40 family.

645991:SGLY RS03500
gene id: 645991:SGLY_RS03500
uniprot id: F0T0H9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS03120
gene id: 645991:SGLY_RS03120
uniprot id: F0SZV7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

645991:SGLY RS01975
gene id: 645991:SGLY_RS01975
uniprot id: F0SXZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS12120
gene id: 645991:SGLY_RS12120
uniprot id: F0SVC5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

645991:SGLY RS08045
gene id: 645991:SGLY_RS08045
uniprot id: F0SY77
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS15345
gene id: 645991:SGLY_RS15345
uniprot id: F0T0F7
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS01120
gene id: 645991:SGLY_RS01120
uniprot id: F0SWA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

645991:SGLY RS04935
gene id: 645991:SGLY_RS04935
uniprot id: F0T2J8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

645991:SGLY RS00675
gene id: 645991:SGLY_RS00675
uniprot id: F0SVM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

645991:SGLY RS01575
gene id: 645991:SGLY_RS01575
uniprot id: F0SWX3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

645991:SGLY RS04975
gene id: 645991:SGLY_RS04975
uniprot id: F0T2K6
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS07660
gene id: 645991:SGLY_RS07660
uniprot id: F0SXK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645991:SGLY RS10740
gene id: 645991:SGLY_RS10740
uniprot id: F0T2P6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS15195
gene id: 645991:SGLY_RS15195
uniprot id: F0T0C8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

645991:SGLY RS07655
gene id: 645991:SGLY_RS07655
uniprot id: F0SXK2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS09005
gene id: 645991:SGLY_RS09005
uniprot id: F0SZM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

645991:SGLY RS09750
gene id: 645991:SGLY_RS09750
uniprot id: F0T0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

645991:SGLY RS05190
gene id: 645991:SGLY_RS05190
uniprot id: F0STS0
names: Subcellular Location Annotation
messages: Cell membrane

645991:SGLY RS03395
gene id: 645991:SGLY_RS03395
uniprot id: F0T012
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

645991:SGLY RS06340
gene id: 645991:SGLY_RS06340
uniprot id: F0SV77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

645991:SGLY RS03390
gene id: 645991:SGLY_RS03390
uniprot id: F0T011
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

645991:SGLY RS14055
gene id: 645991:SGLY_RS14055
uniprot id: F0SYF7
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16800
gene id: 645991:SGLY_RS16800
uniprot id: F0T2Y1
names: Similarity
messages: Belongs to the leucine-binding protein family.

645991:SGLY RS15185
gene id: 645991:SGLY_RS15185
uniprot id: F0T0C6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

645991:SGLY RS16565
gene id: 645991:SGLY_RS16565
uniprot id: F0T2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

645991:SGLY RS14305
gene id: 645991:SGLY_RS14305
uniprot id: F0SYK9
names: Similarity
messages: Belongs to the P(II) protein family.

645991:SGLY RS10830
gene id: 645991:SGLY_RS10830
uniprot id: F0T2R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS03625
gene id: 645991:SGLY_RS03625
uniprot id: F0T0K5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

645991:SGLY RS14600
gene id: 645991:SGLY_RS14600
uniprot id: F0SZ61
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS15600
gene id: 645991:SGLY_RS15600
uniprot id: F0T108
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

645991:SGLY RS12205
gene id: 645991:SGLY_RS12205
uniprot id: F0SVE2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

645991:SGLY RS08625
gene id: 645991:SGLY_RS08625
uniprot id: F0SYZ3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

645991:SGLY RS07170
gene id: 645991:SGLY_RS07170
uniprot id: F0SWH0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645991:SGLY RS10840
gene id: 645991:SGLY_RS10840
uniprot id: F0T2R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS02480
gene id: 645991:SGLY_RS02480
uniprot id: F0SYP2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS12165
gene id: 645991:SGLY_RS12165
uniprot id: F0SVD4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

645991:SGLY RS10980
gene id: 645991:SGLY_RS10980
uniprot id: F0STW9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

645991:SGLY RS02230
gene id: 645991:SGLY_RS02230
uniprot id: F0SY44
names: Similarity
messages: Belongs to the peptidase M20A family.

645991:SGLY RS08510
gene id: 645991:SGLY_RS08510
uniprot id: F0SYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

645991:SGLY RS06250
gene id: 645991:SGLY_RS06250
uniprot id: F0SV59
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16665
gene id: 645991:SGLY_RS16665
uniprot id: F0T2V5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS00730
gene id: 645991:SGLY_RS00730
uniprot id: F0SVP0
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS08080
gene id: 645991:SGLY_RS08080
uniprot id: F0SY85
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS02980
gene id: 645991:SGLY_RS02980
uniprot id: F0SZD6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

645991:SGLY RS02465
gene id: 645991:SGLY_RS02465
uniprot id: F0SYN9
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS12465
gene id: 645991:SGLY_RS12465
uniprot id: F0SVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

645991:SGLY RS07450
gene id: 645991:SGLY_RS07450
uniprot id: F0SX09
names: Similarity
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

645991:SGLY RS11675
gene id: 645991:SGLY_RS11675
uniprot id: F0SUG4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

645991:SGLY RS13500
gene id: 645991:SGLY_RS13500
uniprot id: F0SXA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

645991:SGLY RS14570
gene id: 645991:SGLY_RS14570
uniprot id: F0SZ55
names: Similarity
messages: Belongs to the DtxR/MntR family.

645991:SGLY RS05645
gene id: 645991:SGLY_RS05645
uniprot id: F0SU62
names: Similarity
messages: Belongs to the UPF0229 family.

645991:SGLY RS02075
gene id: 645991:SGLY_RS02075
uniprot id: F0SY12
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

645991:SGLY RS06325
gene id: 645991:SGLY_RS06325
uniprot id: F0SV74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

645991:SGLY RS02610
gene id: 645991:SGLY_RS02610
uniprot id: F0SYR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

645991:SGLY RS10530
gene id: 645991:SGLY_RS10530
uniprot id: F0T264
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

645991:SGLY RS04900
gene id: 645991:SGLY_RS04900
uniprot id: F0T2J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS02005
gene id: 645991:SGLY_RS02005
uniprot id: F0SXZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

645991:SGLY RS00870
gene id: 645991:SGLY_RS00870
uniprot id: F0SW57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

645991:SGLY RS00660
gene id: 645991:SGLY_RS00660
uniprot id: F0SVM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

645991:SGLY RS03705
gene id: 645991:SGLY_RS03705
uniprot id: F0T0M1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

645991:SGLY RS06905
gene id: 645991:SGLY_RS06905
uniprot id: F0SWC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS07850
gene id: 645991:SGLY_RS07850
uniprot id: F0SXP1
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS04500
gene id: 645991:SGLY_RS04500
uniprot id: F0T1X3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS02970
gene id: 645991:SGLY_RS02970
uniprot id: F0SZD4
names: Similarity
messages: Belongs to the FlgM family.

645991:SGLY RS16105
gene id: 645991:SGLY_RS16105
uniprot id: F0T1Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

645991:SGLY RS14200
gene id: 645991:SGLY_RS14200
uniprot id: F0SYI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

645991:SGLY RS15575
gene id: 645991:SGLY_RS15575
uniprot id: F0T103
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS08610
gene id: 645991:SGLY_RS08610
uniprot id: F0SYZ0
names: Similarity
messages: Belongs to the peptidase M29 family.

645991:SGLY RS05005
gene id: 645991:SGLY_RS05005
uniprot id: F0T2L2
names: Similarity
messages: Belongs to the ArsC family.

645991:SGLY RS11535
gene id: 645991:SGLY_RS11535
uniprot id: F0SUD5
names: Similarity
messages: Belongs to the UPF0102 family.

645991:SGLY RS00040
gene id: 645991:SGLY_RS00040
uniprot id: F0SUH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

645991:SGLY RS12870
gene id: 645991:SGLY_RS12870
uniprot id: F0SWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS01445
gene id: 645991:SGLY_RS01445
uniprot id: F0SWU8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS01110
gene id: 645991:SGLY_RS01110
uniprot id: F0SWA5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

645991:SGLY RS04090
gene id: 645991:SGLY_RS04090
uniprot id: F0T192
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS15460
gene id: 645991:SGLY_RS15460
uniprot id: F0T0Y1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

645991:SGLY RS14425
gene id: 645991:SGLY_RS14425
uniprot id: F0SZ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

645991:SGLY RS05825
gene id: 645991:SGLY_RS05825
uniprot id: F0SUI6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

645991:SGLY RS08890
gene id: 645991:SGLY_RS08890
uniprot id: F0SZK0
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS10770
gene id: 645991:SGLY_RS10770
uniprot id: F0T2Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

645991:SGLY RS16835
gene id: 645991:SGLY_RS16835
uniprot id: F0T2Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

645991:SGLY RS02530
gene id: 645991:SGLY_RS02530
uniprot id: F0SYQ0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

645991:SGLY RS04060
gene id: 645991:SGLY_RS04060
uniprot id: F0T187
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

645991:SGLY RS01995
gene id: 645991:SGLY_RS01995
uniprot id: F0SXZ6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

645991:SGLY RS14560
gene id: 645991:SGLY_RS14560
uniprot id: F0SZ53
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

645991:SGLY RS14365
gene id: 645991:SGLY_RS14365
uniprot id: F0SZ15
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645991:SGLY RS11020
gene id: 645991:SGLY_RS11020
uniprot id: F0STX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

645991:SGLY RS03405
gene id: 645991:SGLY_RS03405
uniprot id: F0T014
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

645991:SGLY RS03140
gene id: 645991:SGLY_RS03140
uniprot id: F0SZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

645991:SGLY RS10940
gene id: 645991:SGLY_RS10940
uniprot id: F0STW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

645991:SGLY RS02070
gene id: 645991:SGLY_RS02070
uniprot id: F0SY11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

645991:SGLY RS05700
gene id: 645991:SGLY_RS05700
uniprot id: F0SU73
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS12980
gene id: 645991:SGLY_RS12980
uniprot id: F0SWM1
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS12525
gene id: 645991:SGLY_RS12525
uniprot id: F0SVZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

645991:SGLY RS14370
gene id: 645991:SGLY_RS14370
uniprot id: F0SZ16
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

645991:SGLY RS17160
gene id: 645991:SGLY_RS17160
uniprot id: F0STX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

645991:SGLY RS11310
gene id: 645991:SGLY_RS11310
uniprot id: F0SU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

645991:SGLY RS15300
gene id: 645991:SGLY_RS15300
uniprot id: F0T0E9
names: Similarity
messages: Belongs to the universal stress protein A family.

645991:SGLY RS03290
gene id: 645991:SGLY_RS03290
uniprot id: F0SZZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

645991:SGLY RS15350
gene id: 645991:SGLY_RS15350
uniprot id: F0T0F8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS08120
gene id: 645991:SGLY_RS08120
uniprot id: F0SY94
names: Similarity
messages: Belongs to the universal stress protein A family.

645991:SGLY RS06020
gene id: 645991:SGLY_RS06020
uniprot id: F0SUM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

645991:SGLY RS03655
gene id: 645991:SGLY_RS03655
uniprot id: F0T0L1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

645991:SGLY RS00975
gene id: 645991:SGLY_RS00975
uniprot id: F0SW77
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

645991:SGLY RS12495
gene id: 645991:SGLY_RS12495
uniprot id: F0SVY8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

645991:SGLY RS03185
gene id: 645991:SGLY_RS03185
uniprot id: F0SZX0
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

645991:SGLY RS01985
gene id: 645991:SGLY_RS01985
uniprot id: F0SXZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

645991:SGLY RS09765
gene id: 645991:SGLY_RS09765
uniprot id: F0T0X0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

645991:SGLY RS04930
gene id: 645991:SGLY_RS04930
uniprot id: F0T2J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

645991:SGLY RS14010
gene id: 645991:SGLY_RS14010
uniprot id: F0SYE9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

645991:SGLY RS12475
gene id: 645991:SGLY_RS12475
uniprot id: F0SVY4
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS08615
gene id: 645991:SGLY_RS08615
uniprot id: F0SYZ1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

645991:SGLY RS07920
gene id: 645991:SGLY_RS07920
uniprot id: F0SXQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

645991:SGLY RS09310
gene id: 645991:SGLY_RS09310
uniprot id: F0T081
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

645991:SGLY RS09470
gene id: 645991:SGLY_RS09470
uniprot id: F0T0R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

645991:SGLY RS03255
gene id: 645991:SGLY_RS03255
uniprot id: F0SZY3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

645991:SGLY RS16295
gene id: 645991:SGLY_RS16295
uniprot id: F0T293
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

645991:SGLY RS10870
gene id: 645991:SGLY_RS10870
uniprot id: F0T2S1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

645991:SGLY RS09215
gene id: 645991:SGLY_RS09215
uniprot id: F0T062
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

645991:SGLY RS15875
gene id: 645991:SGLY_RS15875
uniprot id: F0T1L1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

645991:SGLY RS11990
gene id: 645991:SGLY_RS11990
uniprot id: F0SUW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS01600
gene id: 645991:SGLY_RS01600
uniprot id: F0SXC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS16100
gene id: 645991:SGLY_RS16100
uniprot id: F0T1Q6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

645991:SGLY RS15910
gene id: 645991:SGLY_RS15910
uniprot id: F0T1L9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

645991:SGLY RS02150
gene id: 645991:SGLY_RS02150
uniprot id: F0SY27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

645991:SGLY RS08320
gene id: 645991:SGLY_RS08320
uniprot id: F0SYD6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

645991:SGLY RS14335
gene id: 645991:SGLY_RS14335
uniprot id: F0SYL5
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

645991:SGLY RS08720
gene id: 645991:SGLY_RS08720
uniprot id: F0SZG4
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS10750
gene id: 645991:SGLY_RS10750
uniprot id: F0T2P8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

645991:SGLY RS05980
gene id: 645991:SGLY_RS05980
uniprot id: F0SUL5
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS01135
gene id: 645991:SGLY_RS01135
uniprot id: F0SWB0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

645991:SGLY RS11590
gene id: 645991:SGLY_RS11590
uniprot id: F0SUE6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS07115
gene id: 645991:SGLY_RS07115
uniprot id: F0SWG0
names: Similarity
messages: Belongs to the UPF0251 family.

645991:SGLY RS11345
gene id: 645991:SGLY_RS11345
uniprot id: F0SU97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

645991:SGLY RS04735
gene id: 645991:SGLY_RS04735
uniprot id: F0T2G0
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS14215
gene id: 645991:SGLY_RS14215
uniprot id: F0SYJ0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

645991:SGLY RS10525
gene id: 645991:SGLY_RS10525
uniprot id: F0T263
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

645991:SGLY RS02535
gene id: 645991:SGLY_RS02535
uniprot id: F0SYQ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS10755
gene id: 645991:SGLY_RS10755
uniprot id: F0T2P9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS16750
gene id: 645991:SGLY_RS16750
uniprot id: F0T2X1
names: Similarity
messages: Belongs to the peptidase S16 family.

645991:SGLY RS03150
gene id: 645991:SGLY_RS03150
uniprot id: F0SZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

645991:SGLY RS10580
gene id: 645991:SGLY_RS10580
uniprot id: F0T2L9
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS07480
gene id: 645991:SGLY_RS07480
uniprot id: F0SX15
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

645991:SGLY RS14060
gene id: 645991:SGLY_RS14060
uniprot id: F0SYF8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS00745
gene id: 645991:SGLY_RS00745
uniprot id: F0SVP3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

645991:SGLY RS11895
gene id: 645991:SGLY_RS11895
uniprot id: F0SUU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645991:SGLY RS14520
gene id: 645991:SGLY_RS14520
uniprot id: F0SZ45
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

645991:SGLY RS09015
gene id: 645991:SGLY_RS09015
uniprot id: F0SZM4
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS07860
gene id: 645991:SGLY_RS07860
uniprot id: F0SXP3
names: Similarity
messages: Belongs to the DtxR/MntR family.

645991:SGLY RS14630
gene id: 645991:SGLY_RS14630
uniprot id: F0SZ67
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

645991:SGLY RS12000
gene id: 645991:SGLY_RS12000
uniprot id: F0SUW3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

645991:SGLY RS03535
gene id: 645991:SGLY_RS03535
uniprot id: F0T0I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS15165
gene id: 645991:SGLY_RS15165
uniprot id: F0T0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

645991:SGLY RS16170
gene id: 645991:SGLY_RS16170
uniprot id: F0T1S1
names: Subcellular Location Annotation
messages: Cytoplasm

645991:SGLY RS11785
gene id: 645991:SGLY_RS11785
uniprot id: F0SUS1
names: Similarity
messages: Belongs to the GARS family.

645991:SGLY RS09945
gene id: 645991:SGLY_RS09945
uniprot id: F0T1F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

645991:SGLY RS12620
gene id: 645991:SGLY_RS12620
uniprot id: F0SW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS15495
gene id: 645991:SGLY_RS15495
uniprot id: F0T0Y8
names: Similarity
messages: Belongs to the hyi family.

645991:SGLY RS05935
gene id: 645991:SGLY_RS05935
uniprot id: F0SUK7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

645991:SGLY RS03475
gene id: 645991:SGLY_RS03475
uniprot id: F0T028
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

645991:SGLY RS09230
gene id: 645991:SGLY_RS09230
uniprot id: F0T065
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

645991:SGLY RS02245
gene id: 645991:SGLY_RS02245
uniprot id: F0SY47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

645991:SGLY RS00120
gene id: 645991:SGLY_RS00120
uniprot id: F0SUX7
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS10550
gene id: 645991:SGLY_RS10550
uniprot id: F0T268
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

645991:SGLY RS16600
gene id: 645991:SGLY_RS16600
uniprot id: F0T2U5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

645991:SGLY RS13435
gene id: 645991:SGLY_RS13435
uniprot id: F0SX89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

645991:SGLY RS09770
gene id: 645991:SGLY_RS09770
uniprot id: F0T0X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

645991:SGLY RS03715
gene id: 645991:SGLY_RS03715
uniprot id: F0T0M3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

645991:SGLY RS11840
gene id: 645991:SGLY_RS11840
uniprot id: F0SUT2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

645991:SGLY RS05515
gene id: 645991:SGLY_RS05515
uniprot id: F0SU37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

645991:SGLY RS11360
gene id: 645991:SGLY_RS11360
uniprot id: F0SUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

645991:SGLY RS02985
gene id: 645991:SGLY_RS02985
uniprot id: F0SZD7
names: Similarity
messages: Belongs to the bacterial flagellin family.

645991:SGLY RS06865
gene id: 645991:SGLY_RS06865
uniprot id: F0SVX2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

645991:SGLY RS01115
gene id: 645991:SGLY_RS01115
uniprot id: F0SWA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

645991:SGLY RS00345
gene id: 645991:SGLY_RS00345
uniprot id: F0SV21
names: Similarity
messages: Belongs to the peptidase A24 family.

645991:SGLY RS13400
gene id: 645991:SGLY_RS13400
uniprot id: F0SX84
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

645991:SGLY RS10705
gene id: 645991:SGLY_RS10705
uniprot id: F0T2N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

645991:SGLY RS03355
gene id: 645991:SGLY_RS03355
uniprot id: F0T004
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

645991:SGLY RS16290
gene id: 645991:SGLY_RS16290
uniprot id: F0T292
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

645991:SGLY RS14700
gene id: 645991:SGLY_RS14700
uniprot id: F0SZ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

645991:SGLY RS11485
gene id: 645991:SGLY_RS11485
uniprot id: F0SUC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

645991:SGLY RS10955
gene id: 645991:SGLY_RS10955
uniprot id: F0STW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

645991:SGLY RS12335
gene id: 645991:SGLY_RS12335
uniprot id: F0SVG8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

645991:SGLY RS07410
gene id: 645991:SGLY_RS07410
uniprot id: F0SX01
names: Subcellular Location Annotation
messages: cell wall

645991:SGLY RS13015
gene id: 645991:SGLY_RS13015
uniprot id: F0SWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

645991:SGLY RS08030
gene id: 645991:SGLY_RS08030
uniprot id: F0SY74
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

645991:SGLY RS02400
gene id: 645991:SGLY_RS02400
uniprot id: F0SYM5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

645991:SGLY RS14175
gene id: 645991:SGLY_RS14175
uniprot id: F0SYI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS08445
gene id: 645991:SGLY_RS08445
uniprot id: F0SYV8
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

645991:SGLY RS05490
gene id: 645991:SGLY_RS05490
uniprot id: F0SU32
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

645991:SGLY RS16095
gene id: 645991:SGLY_RS16095
uniprot id: F0T1Q5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS15540
gene id: 645991:SGLY_RS15540
uniprot id: F0T0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

645991:SGLY RS04080
gene id: 645991:SGLY_RS04080
uniprot id: F0T190
names: Similarity
messages: Belongs to the P(II) protein family.

645991:SGLY RS10460
gene id: 645991:SGLY_RS10460
uniprot id: F0T250
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS09105
gene id: 645991:SGLY_RS09105
uniprot id: F0T041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

645991:SGLY RS08225
gene id: 645991:SGLY_RS08225
uniprot id: F0SYB5
names: Similarity
messages: Belongs to the ArsC family.

645991:SGLY RS04915
gene id: 645991:SGLY_RS04915
uniprot id: F0T2J4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

645991:SGLY RS02335
gene id: 645991:SGLY_RS02335
uniprot id: F0SY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

645991:SGLY RS00940
gene id: 645991:SGLY_RS00940
uniprot id: F0SW70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

645991:SGLY RS04955
gene id: 645991:SGLY_RS04955
uniprot id: F0T2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

645991:SGLY RS04490
gene id: 645991:SGLY_RS04490
uniprot id: F0T1X0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645991:SGLY RS01425
gene id: 645991:SGLY_RS01425
uniprot id: F0SWU4
names: Similarity
messages: Belongs to the RutC family.

645991:SGLY RS08485
gene id: 645991:SGLY_RS08485
uniprot id: F0SYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

645991:SGLY RS07125
gene id: 645991:SGLY_RS07125
uniprot id: F0SWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

645991:SGLY RS15585
gene id: 645991:SGLY_RS15585
uniprot id: F0T105
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

645991:SGLY RS01065
gene id: 645991:SGLY_RS01065
uniprot id: F0SW96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

645991:SGLY RS04660
gene id: 645991:SGLY_RS04660
uniprot id: F0T2E9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

645991:SGLY RS02555
gene id: 645991:SGLY_RS02555
uniprot id: F0SYQ5
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS12130
gene id: 645991:SGLY_RS12130
uniprot id: F0SVC7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

645991:SGLY RS13950
gene id: 645991:SGLY_RS13950
uniprot id: F0SXY8
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

645991:SGLY RS16475
gene id: 645991:SGLY_RS16475
uniprot id: F0T2C9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

645991:SGLY RS10885
gene id: 645991:SGLY_RS10885
uniprot id: F0T2S4
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

645991:SGLY RS11920
gene id: 645991:SGLY_RS11920
uniprot id: F0SUU7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

645991:SGLY RS05100
gene id: 645991:SGLY_RS05100
uniprot id: F0STQ4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

645991:SGLY RS06265
gene id: 645991:SGLY_RS06265
uniprot id: F0SV62
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS11760
gene id: 645991:SGLY_RS11760
uniprot id: F0SUR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

645991:SGLY RS14195
gene id: 645991:SGLY_RS14195
uniprot id: F0SYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS04960
gene id: 645991:SGLY_RS04960
uniprot id: F0T2K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

645991:SGLY RS12225
gene id: 645991:SGLY_RS12225
uniprot id: F0SVE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

645991:SGLY RS09495
gene id: 645991:SGLY_RS09495
uniprot id: F0T0R5
names: Similarity
messages: Belongs to the asp23 family.

645991:SGLY RS09455
gene id: 645991:SGLY_RS09455
uniprot id: F0T0Q7
names: Similarity
messages: Belongs to the HdrA family.

645991:SGLY RS02250
gene id: 645991:SGLY_RS02250
uniprot id: F0SY48
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

645991:SGLY RS07390
gene id: 645991:SGLY_RS07390
uniprot id: F0SWZ7
names: Subcellular Location Annotation
messages: cell wall

645991:SGLY RS00960
gene id: 645991:SGLY_RS00960
uniprot id: F0SW74
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

645991:SGLY RS09060
gene id: 645991:SGLY_RS09060
uniprot id: F0T032
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

645991:SGLY RS08665
gene id: 645991:SGLY_RS08665
uniprot id: F0SZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

645991:SGLY RS16995
gene id: 645991:SGLY_RS16995
uniprot id: F0T1T1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

645991:SGLY RS15055
gene id: 645991:SGLY_RS15055
uniprot id: F0SZV1
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS00955
gene id: 645991:SGLY_RS00955
uniprot id: F0SW73
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

645991:SGLY RS00880
gene id: 645991:SGLY_RS00880
uniprot id: F0SW59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS07370
gene id: 645991:SGLY_RS07370
uniprot id: F0SWZ3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS06645
gene id: 645991:SGLY_RS06645
uniprot id: F0SVS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

645991:SGLY RS08115
gene id: 645991:SGLY_RS08115
uniprot id: F0SY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

645991:SGLY RS00920
gene id: 645991:SGLY_RS00920
uniprot id: F0SW67
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

645991:SGLY RS16705
gene id: 645991:SGLY_RS16705
uniprot id: F0T2W3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16050
gene id: 645991:SGLY_RS16050
uniprot id: F0T1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

645991:SGLY RS05130
gene id: 645991:SGLY_RS05130
uniprot id: F0STR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS08520
gene id: 645991:SGLY_RS08520
uniprot id: F0SYX3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

645991:SGLY RS14455
gene id: 645991:SGLY_RS14455
uniprot id: F0SZ32
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

645991:SGLY RS13525
gene id: 645991:SGLY_RS13525
uniprot id: F0SXA7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

645991:SGLY RS10640
gene id: 645991:SGLY_RS10640
uniprot id: F0T2N2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS07515
gene id: 645991:SGLY_RS07515
uniprot id: F0SX22
names: Similarity
messages: Belongs to the CpsD/CapB family.

645991:SGLY RS11220
gene id: 645991:SGLY_RS11220
uniprot id: F0STZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

645991:SGLY RS03495
gene id: 645991:SGLY_RS03495
uniprot id: F0T0H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

645991:SGLY RS15175
gene id: 645991:SGLY_RS15175
uniprot id: F0T0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

645991:SGLY RS11295
gene id: 645991:SGLY_RS11295
uniprot id: F0SU14
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

645991:SGLY RS01125
gene id: 645991:SGLY_RS01125
uniprot id: F0SWA8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

645991:SGLY RS16000
gene id: 645991:SGLY_RS16000
uniprot id: F0T1N9
names: Similarity
messages: Belongs to the universal stress protein A family.

645991:SGLY RS15040
gene id: 645991:SGLY_RS15040
uniprot id: F0SZU8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

645991:SGLY RS10730
gene id: 645991:SGLY_RS10730
uniprot id: F0T2P4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

645991:SGLY RS02460
gene id: 645991:SGLY_RS02460
uniprot id: F0SYN8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

645991:SGLY RS15160
gene id: 645991:SGLY_RS15160
uniprot id: F0T0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

645991:SGLY RS01605
gene id: 645991:SGLY_RS01605
uniprot id: F0SXC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645991:SGLY RS11845
gene id: 645991:SGLY_RS11845
uniprot id: F0SUT3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

645991:SGLY RS01955
gene id: 645991:SGLY_RS01955
uniprot id: F0SXJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

645991:SGLY RS10405
gene id: 645991:SGLY_RS10405
uniprot id: F0T237
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS07695
gene id: 645991:SGLY_RS07695
uniprot id: F0SXL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

645991:SGLY RS01140
gene id: 645991:SGLY_RS01140
uniprot id: F0SWB1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

645991:SGLY RS07380
gene id: 645991:SGLY_RS07380
uniprot id: F0SWZ5
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS08655
gene id: 645991:SGLY_RS08655
uniprot id: F0SZ00
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS06885
gene id: 645991:SGLY_RS06885
uniprot id: F0SVX6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

645991:SGLY RS01475
gene id: 645991:SGLY_RS01475
uniprot id: F0SWV3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS11245
gene id: 645991:SGLY_RS11245
uniprot id: F0SU04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

645991:SGLY RS12790
gene id: 645991:SGLY_RS12790
uniprot id: F0SW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS13440
gene id: 645991:SGLY_RS13440
uniprot id: F0SX90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

645991:SGLY RS06315
gene id: 645991:SGLY_RS06315
uniprot id: F0SV72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

645991:SGLY RS10700
gene id: 645991:SGLY_RS10700
uniprot id: F0T2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS15180
gene id: 645991:SGLY_RS15180
uniprot id: F0T0C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

645991:SGLY RS16325
gene id: 645991:SGLY_RS16325
uniprot id: F0T299
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

645991:SGLY RS10155
gene id: 645991:SGLY_RS10155
uniprot id: F0T1J3
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

645991:SGLY RS01650
gene id: 645991:SGLY_RS01650
uniprot id: F0SXD0
names: Similarity
messages: Belongs to the HsdR family.

645991:SGLY RS09935
gene id: 645991:SGLY_RS09935
uniprot id: F0T1E8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16725
gene id: 645991:SGLY_RS16725
uniprot id: F0T2W7
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS04550
gene id: 645991:SGLY_RS04550
uniprot id: F0T1Y3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

645991:SGLY RS04940
gene id: 645991:SGLY_RS04940
uniprot id: F0T2J9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

645991:SGLY RS16555
gene id: 645991:SGLY_RS16555
uniprot id: F0T2T6
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

645991:SGLY RS14610
gene id: 645991:SGLY_RS14610
uniprot id: F0SZ63
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

645991:SGLY RS11215
gene id: 645991:SGLY_RS11215
uniprot id: F0STZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

645991:SGLY RS07315
gene id: 645991:SGLY_RS07315
uniprot id: F0SWY2
names: Similarity
messages: Belongs to the serpin family.

645991:SGLY RS12060
gene id: 645991:SGLY_RS12060
uniprot id: F0SVB6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

645991:SGLY RS00185
gene id: 645991:SGLY_RS00185
uniprot id: F0SUY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

645991:SGLY RS11285
gene id: 645991:SGLY_RS11285
uniprot id: F0SU12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

645991:SGLY RS12315
gene id: 645991:SGLY_RS12315
uniprot id: F0SVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

645991:SGLY RS08200
gene id: 645991:SGLY_RS08200
uniprot id: F0SYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

645991:SGLY RS10900
gene id: 645991:SGLY_RS10900
uniprot id: F0T2S4
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

645991:SGLY RS16080
gene id: 645991:SGLY_RS16080
uniprot id: F0T1Q2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

645991:SGLY RS03635
gene id: 645991:SGLY_RS03635
uniprot id: F0T0K7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

645991:SGLY RS02015
gene id: 645991:SGLY_RS02015
uniprot id: F0SY00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

645991:SGLY RS10880
gene id: 645991:SGLY_RS10880
uniprot id: F0T2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

645991:SGLY RS14245
gene id: 645991:SGLY_RS14245
uniprot id: F0SYJ6
names: Similarity
messages: Belongs to the NifX/NifY family.

645991:SGLY RS08775
gene id: 645991:SGLY_RS08775
uniprot id: F0SZH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

645991:SGLY RS08660
gene id: 645991:SGLY_RS08660
uniprot id: F0SZ01
names: Similarity
messages: Belongs to the UPF0173 family.

645991:SGLY RS16185
gene id: 645991:SGLY_RS16185
uniprot id: F0T1S4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

645991:SGLY RS11995
gene id: 645991:SGLY_RS11995
uniprot id: F0SUW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

645991:SGLY RS02590
gene id: 645991:SGLY_RS02590
uniprot id: F0SYR2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS04545
gene id: 645991:SGLY_RS04545
uniprot id: F0T1Y2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

645991:SGLY RS15905
gene id: 645991:SGLY_RS15905
uniprot id: F0T1L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

645991:SGLY RS10320
gene id: 645991:SGLY_RS10320
uniprot id: F0T222
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS00060
gene id: 645991:SGLY_RS00060
uniprot id: F0SUH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

645991:SGLY RS08275
gene id: 645991:SGLY_RS08275
uniprot id: F0SYC5
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS04835
gene id: 645991:SGLY_RS04835
uniprot id: F0T2H8
names: Similarity
messages: Belongs to the peptidase S66 family.

645991:SGLY RS11025
gene id: 645991:SGLY_RS11025
uniprot id: F0STX8
names: Similarity
messages: Belongs to the CinA family.

645991:SGLY RS11225
gene id: 645991:SGLY_RS11225
uniprot id: F0SU00
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

645991:SGLY RS07950
gene id: 645991:SGLY_RS07950
uniprot id: F0SXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

645991:SGLY RS10720
gene id: 645991:SGLY_RS10720
uniprot id: F0T2P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS10780
gene id: 645991:SGLY_RS10780
uniprot id: F0T2Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

645991:SGLY RS03055
gene id: 645991:SGLY_RS03055
uniprot id: F0SZF0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

645991:SGLY RS16470
gene id: 645991:SGLY_RS16470
uniprot id: F0T2C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

645991:SGLY RS16230
gene id: 645991:SGLY_RS16230
uniprot id: F0T280
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

645991:SGLY RS07475
gene id: 645991:SGLY_RS07475
uniprot id: F0SX14
names: Similarity
messages: Belongs to the DtxR/MntR family.

645991:SGLY RS00825
gene id: 645991:SGLY_RS00825
uniprot id: F0SVQ8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

645991:SGLY RS09100
gene id: 645991:SGLY_RS09100
uniprot id: F0T040
names: Similarity
messages: Belongs to the P(II) protein family.

645991:SGLY RS16220
gene id: 645991:SGLY_RS16220
uniprot id: F0T278
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

645991:SGLY RS08135
gene id: 645991:SGLY_RS08135
uniprot id: F0SY97
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

645991:SGLY RS15940
gene id: 645991:SGLY_RS15940
uniprot id: F0T1M7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

645991:SGLY RS11390
gene id: 645991:SGLY_RS11390
uniprot id: F0SUA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

645991:SGLY RS14565
gene id: 645991:SGLY_RS14565
uniprot id: F0SZ54
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

645991:SGLY RS01615
gene id: 645991:SGLY_RS01615
uniprot id: F0SXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

645991:SGLY RS16550
gene id: 645991:SGLY_RS16550
uniprot id: F0T2T5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

645991:SGLY RS13620
gene id: 645991:SGLY_RS13620
uniprot id: F0SXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS16365
gene id: 645991:SGLY_RS16365
uniprot id: F0T2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

645991:SGLY RS00455
gene id: 645991:SGLY_RS00455
uniprot id: F0SV43
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

645991:SGLY RS18175
gene id: 645991:SGLY_RS18175
uniprot id: F0SYH0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

645991:SGLY RS08240
gene id: 645991:SGLY_RS08240
uniprot id: F0SYB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

645991:SGLY RS11365
gene id: 645991:SGLY_RS11365
uniprot id: F0SUA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

645991:SGLY RS07895
gene id: 645991:SGLY_RS07895
uniprot id: F0SXQ0
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16650
gene id: 645991:SGLY_RS16650
uniprot id: F0T2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

645991:SGLY RS12245
gene id: 645991:SGLY_RS12245
uniprot id: F0SVF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

645991:SGLY RS12515
gene id: 645991:SGLY_RS12515
uniprot id: F0SVZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

645991:SGLY RS07295
gene id: 645991:SGLY_RS07295
uniprot id: F0SWX9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

645991:SGLY RS00680
gene id: 645991:SGLY_RS00680
uniprot id: F0SVN0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS08780
gene id: 645991:SGLY_RS08780
uniprot id: F0SZH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645991:SGLY RS01340
gene id: 645991:SGLY_RS01340
uniprot id: F0SWT2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645991:SGLY RS12015
gene id: 645991:SGLY_RS12015
uniprot id: F0SUW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

645991:SGLY RS05710
gene id: 645991:SGLY_RS05710
uniprot id: F0SU75
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

645991:SGLY RS01005
gene id: 645991:SGLY_RS01005
uniprot id: F0SW84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

645991:SGLY RS02105
gene id: 645991:SGLY_RS02105
uniprot id: F0SY18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

645991:SGLY RS09325
gene id: 645991:SGLY_RS09325
uniprot id: F0T084
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS00645
gene id: 645991:SGLY_RS00645
uniprot id: F0SVM3
names: Similarity
messages: Belongs to the FrhG family.

645991:SGLY RS16495
gene id: 645991:SGLY_RS16495
uniprot id: F0T2D3
names: Similarity
messages: Belongs to the FemABX family.

645991:SGLY RS00520
gene id: 645991:SGLY_RS00520
uniprot id: F0SVJ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS01195
gene id: 645991:SGLY_RS01195
uniprot id: F0SWB7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

645991:SGLY RS10220
gene id: 645991:SGLY_RS10220
uniprot id: F0T202
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

645991:SGLY RS03720
gene id: 645991:SGLY_RS03720
uniprot id: F0T0M4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

645991:SGLY RS02630
gene id: 645991:SGLY_RS02630
uniprot id: F0SYS0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

645991:SGLY RS02585
gene id: 645991:SGLY_RS02585
uniprot id: F0SYR1
names: Similarity
messages: Belongs to the peptidase C40 family.

645991:SGLY RS07545
gene id: 645991:SGLY_RS07545
uniprot id: F0SX29
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS06185
gene id: 645991:SGLY_RS06185
uniprot id: F0SV47
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS10850
gene id: 645991:SGLY_RS10850
uniprot id: F0T2R7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

645991:SGLY RS01180
gene id: 645991:SGLY_RS01180
uniprot id: F0SWB4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

645991:SGLY RS01500
gene id: 645991:SGLY_RS01500
uniprot id: F0SWV8
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

645991:SGLY RS03075
gene id: 645991:SGLY_RS03075
uniprot id: F0SZF4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

645991:SGLY RS02200
gene id: 645991:SGLY_RS02200
uniprot id: F0SY38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

645991:SGLY RS11805
gene id: 645991:SGLY_RS11805
uniprot id: F0SUS5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

645991:SGLY RS03060
gene id: 645991:SGLY_RS03060
uniprot id: F0SZF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

645991:SGLY RS04885
gene id: 645991:SGLY_RS04885
uniprot id: F0T2I8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS16500
gene id: 645991:SGLY_RS16500
uniprot id: F0T2D4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS15470
gene id: 645991:SGLY_RS15470
uniprot id: F0T0Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

645991:SGLY RS16065
gene id: 645991:SGLY_RS16065
uniprot id: F0T1P9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

645991:SGLY RS02515
gene id: 645991:SGLY_RS02515
uniprot id: F0SYP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

645991:SGLY RS08840
gene id: 645991:SGLY_RS08840
uniprot id: F0SZI9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

645991:SGLY RS01990
gene id: 645991:SGLY_RS01990
uniprot id: F0SXZ5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

645991:SGLY RS10775
gene id: 645991:SGLY_RS10775
uniprot id: F0T2Q3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

645991:SGLY RS08880
gene id: 645991:SGLY_RS08880
uniprot id: F0SZJ8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

645991:SGLY RS06995
gene id: 645991:SGLY_RS06995
uniprot id: F0SWD6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

645991:SGLY RS13920
gene id: 645991:SGLY_RS13920
uniprot id: F0SXY2
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

645991:SGLY RS02660
gene id: 645991:SGLY_RS02660
uniprot id: F0SYS6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

645991:SGLY RS03325
gene id: 645991:SGLY_RS03325
uniprot id: F0SZZ8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS03580
gene id: 645991:SGLY_RS03580
uniprot id: F0T0J6
names: Similarity
messages: Belongs to the manganese catalase family.

645991:SGLY RS15260
gene id: 645991:SGLY_RS15260
uniprot id: F0T0E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

645991:SGLY RS00635
gene id: 645991:SGLY_RS00635
uniprot id: F0SVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

645991:SGLY RS09910
gene id: 645991:SGLY_RS09910
uniprot id: F0T1E4
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS15140
gene id: 645991:SGLY_RS15140
uniprot id: F0T0B6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS06600
gene id: 645991:SGLY_RS06600
uniprot id: F0SVS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS08860
gene id: 645991:SGLY_RS08860
uniprot id: F0SZJ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

645991:SGLY RS16795
gene id: 645991:SGLY_RS16795
uniprot id: F0T2Y0
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16700
gene id: 645991:SGLY_RS16700
uniprot id: F0T2W2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS01440
gene id: 645991:SGLY_RS01440
uniprot id: F0SWU7
names: Similarity
messages: Belongs to the manganese catalase family.

645991:SGLY RS08165
gene id: 645991:SGLY_RS08165
uniprot id: F0SYA3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS04650
gene id: 645991:SGLY_RS04650
uniprot id: F0T2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

645991:SGLY RS13535
gene id: 645991:SGLY_RS13535
uniprot id: F0SXA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

645991:SGLY RS04240
gene id: 645991:SGLY_RS04240
uniprot id: F0T1C3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS03210
gene id: 645991:SGLY_RS03210
uniprot id: F0SZX5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

645991:SGLY RS15870
gene id: 645991:SGLY_RS15870
uniprot id: F0T1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

645991:SGLY RS03540
gene id: 645991:SGLY_RS03540
uniprot id: F0T0I7
names: Similarity
messages: Belongs to the YicC/YloC family.

645991:SGLY RS02620
gene id: 645991:SGLY_RS02620
uniprot id: F0SYR8
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

645991:SGLY RS12390
gene id: 645991:SGLY_RS12390
uniprot id: F0SVH9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

645991:SGLY RS07745
gene id: 645991:SGLY_RS07745
uniprot id: F0SXM0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

645991:SGLY RS12590
gene id: 645991:SGLY_RS12590
uniprot id: F0SW06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

645991:SGLY RS10325
gene id: 645991:SGLY_RS10325
uniprot id: F0T223
names: Similarity
messages: Belongs to the DnaA family.

645991:SGLY RS01460
gene id: 645991:SGLY_RS01460
uniprot id: F0SWV0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

645991:SGLY RS02665
gene id: 645991:SGLY_RS02665
uniprot id: F0SYS7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645991:SGLY RS06390
gene id: 645991:SGLY_RS06390
uniprot id: F0SV85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

645991:SGLY RS05520
gene id: 645991:SGLY_RS05520
uniprot id: F0SU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

645991:SGLY RS03650
gene id: 645991:SGLY_RS03650
uniprot id: F0T0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

645991:SGLY RS01270
gene id: 645991:SGLY_RS01270
uniprot id: F0SWR8
names: Similarity
messages: Belongs to the UPF0045 family.

645991:SGLY RS16535
gene id: 645991:SGLY_RS16535
uniprot id: F0T2E1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS11030
gene id: 645991:SGLY_RS11030
uniprot id: F0STX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

645991:SGLY RS00125
gene id: 645991:SGLY_RS00125
uniprot id: F0SUX8
names: Similarity
messages: Belongs to the peptidase A8 family.

645991:SGLY RS11900
gene id: 645991:SGLY_RS11900
uniprot id: F0SUU4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS08535
gene id: 645991:SGLY_RS08535
uniprot id: F0SYX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

645991:SGLY RS13405
gene id: 645991:SGLY_RS13405
uniprot id: F0SX85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

645991:SGLY RS00650
gene id: 645991:SGLY_RS00650
uniprot id: F0SVM4
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS00625
gene id: 645991:SGLY_RS00625
uniprot id: F0SVL9
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS09200
gene id: 645991:SGLY_RS09200
uniprot id: F0T059
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS16660
gene id: 645991:SGLY_RS16660
uniprot id: F0T2V4
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS00990
gene id: 645991:SGLY_RS00990
uniprot id: F0SW80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

645991:SGLY RS11050
gene id: 645991:SGLY_RS11050
uniprot id: F0STY3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

645991:SGLY RS02170
gene id: 645991:SGLY_RS02170
uniprot id: F0SY32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

645991:SGLY RS14530
gene id: 645991:SGLY_RS14530
uniprot id: F0SZ47
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS10265
gene id: 645991:SGLY_RS10265
uniprot id: F0T211
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS15425
gene id: 645991:SGLY_RS15425
uniprot id: F0T0H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

645991:SGLY RS00815
gene id: 645991:SGLY_RS00815
uniprot id: F0SVQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

645991:SGLY RS07200
gene id: 645991:SGLY_RS07200
uniprot id: F0SWH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS13555
gene id: 645991:SGLY_RS13555
uniprot id: F0SXB3
names: Similarity
messages: Belongs to the UPF0751 family.

645991:SGLY RS14140
gene id: 645991:SGLY_RS14140
uniprot id: F0SYH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

645991:SGLY RS03740
gene id: 645991:SGLY_RS03740
uniprot id: F0T0M8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

645991:SGLY RS07180
gene id: 645991:SGLY_RS07180
uniprot id: F0SWH2
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

645991:SGLY RS10895
gene id: 645991:SGLY_RS10895
uniprot id: F0T2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

645991:SGLY RS11620
gene id: 645991:SGLY_RS11620
uniprot id: F0SUF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

645991:SGLY RS12170
gene id: 645991:SGLY_RS12170
uniprot id: F0SVD5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

645991:SGLY RS03300
gene id: 645991:SGLY_RS03300
uniprot id: F0SZZ3
names: Similarity
messages: Belongs to the transpeptidase family.

645991:SGLY RS09785
gene id: 645991:SGLY_RS09785
uniprot id: F0T0X4
names: Similarity
messages: Belongs to the threonine synthase family.

645991:SGLY RS12630
gene id: 645991:SGLY_RS12630
uniprot id: F0SW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS11705
gene id: 645991:SGLY_RS11705
uniprot id: F0SUQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

645991:SGLY RS14310
gene id: 645991:SGLY_RS14310
uniprot id: F0SYL0
names: Similarity
messages: Belongs to the P(II) protein family.

645991:SGLY RS09305
gene id: 645991:SGLY_RS09305
uniprot id: F0T080
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

645991:SGLY RS03965
gene id: 645991:SGLY_RS03965
uniprot id: F0T169
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

645991:SGLY RS13300
gene id: 645991:SGLY_RS13300
uniprot id: F0SX66
names: Similarity
messages: Belongs to the MotB family.

645991:SGLY RS06630
gene id: 645991:SGLY_RS06630
uniprot id: F0SVS6
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

645991:SGLY RS02000
gene id: 645991:SGLY_RS02000
uniprot id: F0SXZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

645991:SGLY RS03205
gene id: 645991:SGLY_RS03205
uniprot id: F0SZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

645991:SGLY RS06065
gene id: 645991:SGLY_RS06065
uniprot id: F0SUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

645991:SGLY RS09120
gene id: 645991:SGLY_RS09120
uniprot id: F0T044
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

645991:SGLY RS08230
gene id: 645991:SGLY_RS08230
uniprot id: F0SYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

645991:SGLY RS00965
gene id: 645991:SGLY_RS00965
uniprot id: F0SW75
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

645991:SGLY RS03455
gene id: 645991:SGLY_RS03455
uniprot id: F0T024
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

645991:SGLY RS10515
gene id: 645991:SGLY_RS10515
uniprot id: F0T261
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

645991:SGLY RS04570
gene id: 645991:SGLY_RS04570
uniprot id: F0T1Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

645991:SGLY RS10400
gene id: 645991:SGLY_RS10400
uniprot id: F0T236
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

645991:SGLY RS10425
gene id: 645991:SGLY_RS10425
uniprot id: F0T242
names: Subcellular Location Annotation
messages: Nucleus

645991:SGLY RS05475
gene id: 645991:SGLY_RS05475
uniprot id: F0SU29
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

645991:SGLY RS12435
gene id: 645991:SGLY_RS12435
uniprot id: F0SVI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

645991:SGLY RS06945
gene id: 645991:SGLY_RS06945
uniprot id: F0SWC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

645991:SGLY RS06595
gene id: 645991:SGLY_RS06595
uniprot id: F0SVR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS00100
gene id: 645991:SGLY_RS00100
uniprot id: F0SUX3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

645991:SGLY RS11445
gene id: 645991:SGLY_RS11445
uniprot id: F0SUB7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

645991:SGLY RS08455
gene id: 645991:SGLY_RS08455
uniprot id: F0SYW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

645991:SGLY RS07590
gene id: 645991:SGLY_RS07590
uniprot id: F0SX38
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

645991:SGLY RS14405
gene id: 645991:SGLY_RS14405
uniprot id: F0SZ22
names: Similarity
messages: Belongs to the TrpF family.

645991:SGLY RS02545
gene id: 645991:SGLY_RS02545
uniprot id: F0SYQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS01560
gene id: 645991:SGLY_RS01560
uniprot id: F0SWX0
names: Similarity
messages: Belongs to the CtsR family.

645991:SGLY RS05480
gene id: 645991:SGLY_RS05480
uniprot id: F0SU30
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

645991:SGLY RS02995
gene id: 645991:SGLY_RS02995
uniprot id: F0SZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

645991:SGLY RS14395
gene id: 645991:SGLY_RS14395
uniprot id: F0SZ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

645991:SGLY RS11010
gene id: 645991:SGLY_RS11010
uniprot id: F0STX5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

645991:SGLY RS08155
gene id: 645991:SGLY_RS08155
uniprot id: F0SYA1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

645991:SGLY RS12520
gene id: 645991:SGLY_RS12520
uniprot id: F0SVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

645991:SGLY RS06200
gene id: 645991:SGLY_RS06200
uniprot id: F0SV49
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS04460
gene id: 645991:SGLY_RS04460
uniprot id: F0T1W3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS16505
gene id: 645991:SGLY_RS16505
uniprot id: F0T2D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

645991:SGLY RS00010
gene id: 645991:SGLY_RS00010
uniprot id: F0SUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

645991:SGLY RS01315
gene id: 645991:SGLY_RS01315
uniprot id: F0SWS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

645991:SGLY RS09685
gene id: 645991:SGLY_RS09685
uniprot id: F0T0V4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

645991:SGLY RS11665
gene id: 645991:SGLY_RS11665
uniprot id: F0SUG2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

645991:SGLY RS10275
gene id: 645991:SGLY_RS10275
uniprot id: F0T213
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

645991:SGLY RS02040
gene id: 645991:SGLY_RS02040
uniprot id: F0SY05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

645991:SGLY RS14190
gene id: 645991:SGLY_RS14190
uniprot id: F0SYI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS02035
gene id: 645991:SGLY_RS02035
uniprot id: F0SY04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

645991:SGLY RS10000
gene id: 645991:SGLY_RS10000
uniprot id: F0T1G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

645991:SGLY RS02165
gene id: 645991:SGLY_RS02165
uniprot id: F0SY30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

645991:SGLY RS15325
gene id: 645991:SGLY_RS15325
uniprot id: F0T0F3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS12615
gene id: 645991:SGLY_RS12615
uniprot id: F0SW11
names: Similarity
messages: Belongs to the asparaginase 1 family.

645991:SGLY RS03460
gene id: 645991:SGLY_RS03460
uniprot id: F0T025
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

645991:SGLY RS07495
gene id: 645991:SGLY_RS07495
uniprot id: F0SX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS07875
gene id: 645991:SGLY_RS07875
uniprot id: F0SXP6
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS14665
gene id: 645991:SGLY_RS14665
uniprot id: F0SZ74
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS04410
gene id: 645991:SGLY_RS04410
uniprot id: F0T1V2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS05790
gene id: 645991:SGLY_RS05790
uniprot id: F0SU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS09075
gene id: 645991:SGLY_RS09075
uniprot id: F0T035
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS01085
gene id: 645991:SGLY_RS01085
uniprot id: F0SWA0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

645991:SGLY RS13490
gene id: 645991:SGLY_RS13490
uniprot id: F0SXA0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

645991:SGLY RS12940
gene id: 645991:SGLY_RS12940
uniprot id: F0SWL3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS15295
gene id: 645991:SGLY_RS15295
uniprot id: F0T0E8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS09630
gene id: 645991:SGLY_RS09630
uniprot id: F0T0U3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

645991:SGLY RS17970
gene id: 645991:SGLY_RS17970
uniprot id: F0T0Z8
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

645991:SGLY RS11130
gene id: 645991:SGLY_RS11130
uniprot id: F0STZ5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS05155
gene id: 645991:SGLY_RS05155
uniprot id: F0STR5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS11755
gene id: 645991:SGLY_RS11755
uniprot id: F0SUR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

645991:SGLY RS07385
gene id: 645991:SGLY_RS07385
uniprot id: F0SWZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

645991:SGLY RS07935
gene id: 645991:SGLY_RS07935
uniprot id: F0SXQ8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

645991:SGLY RS13645
gene id: 645991:SGLY_RS13645
uniprot id: F0SXT1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS02160
gene id: 645991:SGLY_RS02160
uniprot id: F0SY29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

645991:SGLY RS08420
gene id: 645991:SGLY_RS08420
uniprot id: F0SYV3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS11595
gene id: 645991:SGLY_RS11595
uniprot id: F0SUE7
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

645991:SGLY RS06445
gene id: 645991:SGLY_RS06445
uniprot id: F0SV95
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16450
gene id: 645991:SGLY_RS16450
uniprot id: F0T2C4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

645991:SGLY RS15200
gene id: 645991:SGLY_RS15200
uniprot id: F0T0C9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

645991:SGLY RS04625
gene id: 645991:SGLY_RS04625
uniprot id: F0T1Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

645991:SGLY RS13275
gene id: 645991:SGLY_RS13275
uniprot id: F0SX61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

645991:SGLY RS11550
gene id: 645991:SGLY_RS11550
uniprot id: F0SUD8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

645991:SGLY RS11525
gene id: 645991:SGLY_RS11525
uniprot id: F0SUD3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

645991:SGLY RS10535
gene id: 645991:SGLY_RS10535
uniprot id: F0T265
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

645991:SGLY RS07625
gene id: 645991:SGLY_RS07625
uniprot id: F0SX45
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

645991:SGLY RS14300
gene id: 645991:SGLY_RS14300
uniprot id: F0SYK8
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

645991:SGLY RS13730
gene id: 645991:SGLY_RS13730
uniprot id: F0SXU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS10745
gene id: 645991:SGLY_RS10745
uniprot id: F0T2P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

645991:SGLY RS07910
gene id: 645991:SGLY_RS07910
uniprot id: F0SXQ3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

645991:SGLY RS07715
gene id: 645991:SGLY_RS07715
uniprot id: F0SXL4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS13830
gene id: 645991:SGLY_RS13830
uniprot id: F0SXW6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS10410
gene id: 645991:SGLY_RS10410
uniprot id: F0T238
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

645991:SGLY RS03450
gene id: 645991:SGLY_RS03450
uniprot id: F0T023
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

645991:SGLY RS13725
gene id: 645991:SGLY_RS13725
uniprot id: F0SXU6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

645991:SGLY RS00935
gene id: 645991:SGLY_RS00935
uniprot id: F0SW69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

645991:SGLY RS08305
gene id: 645991:SGLY_RS08305
uniprot id: F0SYD3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16775
gene id: 645991:SGLY_RS16775
uniprot id: F0T2X6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

645991:SGLY RS10485
gene id: 645991:SGLY_RS10485
uniprot id: F0T255
names: Similarity
messages: Belongs to the RecJ family.

645991:SGLY RS15475
gene id: 645991:SGLY_RS15475
uniprot id: F0T0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

645991:SGLY RS14465
gene id: 645991:SGLY_RS14465
uniprot id: F0SZ34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645991:SGLY RS15210
gene id: 645991:SGLY_RS15210
uniprot id: F0T0D1
names: Similarity
messages: Belongs to the fabD family.

645991:SGLY RS11985
gene id: 645991:SGLY_RS11985
uniprot id: F0SUW0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

645991:SGLY RS11970
gene id: 645991:SGLY_RS11970
uniprot id: F0SUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

645991:SGLY RS14030
gene id: 645991:SGLY_RS14030
uniprot id: F0SYF3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

645991:SGLY RS12455
gene id: 645991:SGLY_RS12455
uniprot id: F0SVY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

645991:SGLY RS05705
gene id: 645991:SGLY_RS05705
uniprot id: F0SU74
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

645991:SGLY RS02310
gene id: 645991:SGLY_RS02310
uniprot id: F0SY60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

645991:SGLY RS00620
gene id: 645991:SGLY_RS00620
uniprot id: F0SVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

645991:SGLY RS03545
gene id: 645991:SGLY_RS03545
uniprot id: F0T0I8
names: Similarity
messages: Belongs to the RemA family.

645991:SGLY RS16390
gene id: 645991:SGLY_RS16390
uniprot id: F0T2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

645991:SGLY RS04300
gene id: 645991:SGLY_RS04300
uniprot id: F0T1T3
names: Similarity
messages: Belongs to the HsdR family.

645991:SGLY RS16545
gene id: 645991:SGLY_RS16545
uniprot id: F0T2E3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS03070
gene id: 645991:SGLY_RS03070
uniprot id: F0SZF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

645991:SGLY RS05670
gene id: 645991:SGLY_RS05670
uniprot id: F0SU67
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS15150
gene id: 645991:SGLY_RS15150
uniprot id: F0T0B8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

645991:SGLY RS14270
gene id: 645991:SGLY_RS14270
uniprot id: F0SYK1
names: Similarity
messages: Belongs to the P(II) protein family.

645991:SGLY RS07755
gene id: 645991:SGLY_RS07755
uniprot id: F0SXM2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

645991:SGLY RS14595
gene id: 645991:SGLY_RS14595
uniprot id: F0SZ60
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS06950
gene id: 645991:SGLY_RS06950
uniprot id: F0SWC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

645991:SGLY RS03795
gene id: 645991:SGLY_RS03795
uniprot id: F0T0N6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS08920
gene id: 645991:SGLY_RS08920
uniprot id: F0SZK6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS08835
gene id: 645991:SGLY_RS08835
uniprot id: F0SZI8
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

645991:SGLY RS09955
gene id: 645991:SGLY_RS09955
uniprot id: F0T1F2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS10505
gene id: 645991:SGLY_RS10505
uniprot id: F0T259
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

645991:SGLY RS09435
gene id: 645991:SGLY_RS09435
uniprot id: F0T0Q3
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

645991:SGLY RS08450
gene id: 645991:SGLY_RS08450
uniprot id: F0SYV9
names: Similarity
messages: Belongs to the UPF0735 family.

645991:SGLY RS04565
gene id: 645991:SGLY_RS04565
uniprot id: F0T1Y6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

645991:SGLY RS12960
gene id: 645991:SGLY_RS12960
uniprot id: F0SWL7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

645991:SGLY RS07615
gene id: 645991:SGLY_RS07615
uniprot id: F0SX43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

645991:SGLY RS14470
gene id: 645991:SGLY_RS14470
uniprot id: F0SZ35
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

645991:SGLY RS11410
gene id: 645991:SGLY_RS11410
uniprot id: F0SUB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

645991:SGLY RS04850
gene id: 645991:SGLY_RS04850
uniprot id: F0T2I1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

645991:SGLY RS02425
gene id: 645991:SGLY_RS02425
uniprot id: F0SYN0
names: Similarity
messages: Belongs to the hemerythrin family.

645991:SGLY RS08245
gene id: 645991:SGLY_RS08245
uniprot id: F0SYB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

645991:SGLY RS02090
gene id: 645991:SGLY_RS02090
uniprot id: F0SY15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

645991:SGLY RS09130
gene id: 645991:SGLY_RS09130
uniprot id: F0T046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS12240
gene id: 645991:SGLY_RS12240
uniprot id: F0SVE9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

645991:SGLY RS12230
gene id: 645991:SGLY_RS12230
uniprot id: F0SVE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

645991:SGLY RS04740
gene id: 645991:SGLY_RS04740
uniprot id: F0T2G1
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS14720
gene id: 645991:SGLY_RS14720
uniprot id: F0SZN2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

645991:SGLY RS02020
gene id: 645991:SGLY_RS02020
uniprot id: F0SY01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

645991:SGLY RS09690
gene id: 645991:SGLY_RS09690
uniprot id: F0T0V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

645991:SGLY RS01385
gene id: 645991:SGLY_RS01385
uniprot id: F0SWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

645991:SGLY RS03315
gene id: 645991:SGLY_RS03315
uniprot id: F0SZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

645991:SGLY RS12105
gene id: 645991:SGLY_RS12105
uniprot id: F0SVC3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

645991:SGLY RS15500
gene id: 645991:SGLY_RS15500
uniprot id: F0T0Y9
names: Similarity
messages: Belongs to the TPP enzyme family.

645991:SGLY RS10210
gene id: 645991:SGLY_RS10210
uniprot id: F0T200
names: Similarity
messages: Belongs to the HypD family.

645991:SGLY RS09415
gene id: 645991:SGLY_RS09415
uniprot id: F0T0A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

645991:SGLY RS02340
gene id: 645991:SGLY_RS02340
uniprot id: F0SY66
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

645991:SGLY RS02125
gene id: 645991:SGLY_RS02125
uniprot id: F0SY22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

645991:SGLY RS02390
gene id: 645991:SGLY_RS02390
uniprot id: F0SYM3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

645991:SGLY RS01060
gene id: 645991:SGLY_RS01060
uniprot id: F0SW95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

645991:SGLY RS09380
gene id: 645991:SGLY_RS09380
uniprot id: F0T095
names: Similarity
messages: Belongs to the TlyA family.

645991:SGLY RS15075
gene id: 645991:SGLY_RS15075
uniprot id: F0SZV5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

645991:SGLY RS09365
gene id: 645991:SGLY_RS09365
uniprot id: F0T092
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

645991:SGLY RS07230
gene id: 645991:SGLY_RS07230
uniprot id: F0SWI2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS03400
gene id: 645991:SGLY_RS03400
uniprot id: F0T013
names: Similarity
messages: Belongs to the YggT family.

645991:SGLY RS15430
gene id: 645991:SGLY_RS15430
uniprot id: F0T0H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

645991:SGLY RS09020
gene id: 645991:SGLY_RS09020
uniprot id: F0SZM5
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS12500
gene id: 645991:SGLY_RS12500
uniprot id: F0SVY9
names: Similarity
messages: Belongs to the peptidase S16 family.

645991:SGLY RS16420
gene id: 645991:SGLY_RS16420
uniprot id: F0T2B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS03700
gene id: 645991:SGLY_RS03700
uniprot id: F0T0M0
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

645991:SGLY RS05580
gene id: 645991:SGLY_RS05580
uniprot id: F0SU48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS14525
gene id: 645991:SGLY_RS14525
uniprot id: F0SZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

645991:SGLY RS09540
gene id: 645991:SGLY_RS09540
uniprot id: F0T0S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

645991:SGLY RS12265
gene id: 645991:SGLY_RS12265
uniprot id: F0SVF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

645991:SGLY RS16255
gene id: 645991:SGLY_RS16255
uniprot id: F0T285
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

645991:SGLY RS12595
gene id: 645991:SGLY_RS12595
uniprot id: F0SW07
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

645991:SGLY RS15980
gene id: 645991:SGLY_RS15980
uniprot id: F0T1N5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS15245
gene id: 645991:SGLY_RS15245
uniprot id: F0T0D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

645991:SGLY RS14690
gene id: 645991:SGLY_RS14690
uniprot id: F0SZ79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS16780
gene id: 645991:SGLY_RS16780
uniprot id: F0T2X7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

645991:SGLY RS03490
gene id: 645991:SGLY_RS03490
uniprot id: F0T0H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

645991:SGLY RS09395
gene id: 645991:SGLY_RS09395
uniprot id: F0T098
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

645991:SGLY RS00045
gene id: 645991:SGLY_RS00045
uniprot id: F0SUH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS08405
gene id: 645991:SGLY_RS08405
uniprot id: F0SYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

645991:SGLY RS14205
gene id: 645991:SGLY_RS14205
uniprot id: F0SYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

645991:SGLY RS00005
gene id: 645991:SGLY_RS00005
uniprot id: F0SUG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

645991:SGLY RS12425
gene id: 645991:SGLY_RS12425
uniprot id: F0SVI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

645991:SGLY RS00160
gene id: 645991:SGLY_RS00160
uniprot id: F0SUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS05305
gene id: 645991:SGLY_RS05305
uniprot id: F0STT9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS12250
gene id: 645991:SGLY_RS12250
uniprot id: F0SVF1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

645991:SGLY RS06050
gene id: 645991:SGLY_RS06050
uniprot id: F0SUM9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS11655
gene id: 645991:SGLY_RS11655
uniprot id: F0SUF9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

645991:SGLY RS02540
gene id: 645991:SGLY_RS02540
uniprot id: F0SYQ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

645991:SGLY RS16655
gene id: 645991:SGLY_RS16655
uniprot id: F0T2V3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS08050
gene id: 645991:SGLY_RS08050
uniprot id: F0SY78
names: Similarity
messages: Belongs to the CpsD/CapB family.

645991:SGLY RS09610
gene id: 645991:SGLY_RS09610
uniprot id: F0T0T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645991:SGLY RS13565
gene id: 645991:SGLY_RS13565
uniprot id: F0SXB5
names: Similarity
messages: Belongs to the glutamate synthase family.

645991:SGLY RS15225
gene id: 645991:SGLY_RS15225
uniprot id: F0T0D4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

645991:SGLY RS15465
gene id: 645991:SGLY_RS15465
uniprot id: F0T0Y2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16195
gene id: 645991:SGLY_RS16195
uniprot id: F0T272
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

645991:SGLY RS10575
gene id: 645991:SGLY_RS10575
uniprot id: F0T2L8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16145
gene id: 645991:SGLY_RS16145
uniprot id: F0T1R5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

645991:SGLY RS02130
gene id: 645991:SGLY_RS02130
uniprot id: F0SY23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

645991:SGLY RS11540
gene id: 645991:SGLY_RS11540
uniprot id: F0SUD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

645991:SGLY RS04250
gene id: 645991:SGLY_RS04250
uniprot id: F0T1C5
names: Subunit
messages: Interacts directly with the sensor histidine kinase ComP and stimulates its activity.

645991:SGLY RS14635
gene id: 645991:SGLY_RS14635
uniprot id: F0SZ68
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

645991:SGLY RS04695
gene id: 645991:SGLY_RS04695
uniprot id: F0T2F3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645991:SGLY RS00385
gene id: 645991:SGLY_RS00385
uniprot id: F0SV29
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

645991:SGLY RS08530
gene id: 645991:SGLY_RS08530
uniprot id: F0SYX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

645991:SGLY RS02110
gene id: 645991:SGLY_RS02110
uniprot id: F0SY19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

645991:SGLY RS05850
gene id: 645991:SGLY_RS05850
uniprot id: F0SUJ0
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

645991:SGLY RS14230
gene id: 645991:SGLY_RS14230
uniprot id: F0SYJ3
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

645991:SGLY RS15365
gene id: 645991:SGLY_RS15365
uniprot id: F0T0G1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

645991:SGLY RS07960
gene id: 645991:SGLY_RS07960
uniprot id: F0SXR3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

645991:SGLY RS11820
gene id: 645991:SGLY_RS11820
uniprot id: F0SUS8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

645991:SGLY RS16685
gene id: 645991:SGLY_RS16685
uniprot id: F0T2V9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS09375
gene id: 645991:SGLY_RS09375
uniprot id: F0T094
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS02285
gene id: 645991:SGLY_RS02285
uniprot id: F0SY55
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

645991:SGLY RS03200
gene id: 645991:SGLY_RS03200
uniprot id: F0SZX3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

645991:SGLY RS09550
gene id: 645991:SGLY_RS09550
uniprot id: F0T0S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

645991:SGLY RS11625
gene id: 645991:SGLY_RS11625
uniprot id: F0SUF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

645991:SGLY RS01620
gene id: 645991:SGLY_RS01620
uniprot id: F0SXC6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

645991:SGLY RS00985
gene id: 645991:SGLY_RS00985
uniprot id: F0SW79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

645991:SGLY RS15340
gene id: 645991:SGLY_RS15340
uniprot id: F0T0F6
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

645991:SGLY RS15220
gene id: 645991:SGLY_RS15220
uniprot id: F0T0D3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

645991:SGLY RS00580
gene id: 645991:SGLY_RS00580
uniprot id: F0SVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

645991:SGLY RS14100
gene id: 645991:SGLY_RS14100
uniprot id: F0SYG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS04585
gene id: 645991:SGLY_RS04585
uniprot id: F0T1Z0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

645991:SGLY RS13845
gene id: 645991:SGLY_RS13845
uniprot id: F0SXW9
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS15895
gene id: 645991:SGLY_RS15895
uniprot id: F0T1L5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS02240
gene id: 645991:SGLY_RS02240
uniprot id: F0SY46
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

645991:SGLY RS08440
gene id: 645991:SGLY_RS08440
uniprot id: F0SYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

645991:SGLY RS11340
gene id: 645991:SGLY_RS11340
uniprot id: F0SU96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS07445
gene id: 645991:SGLY_RS07445
uniprot id: F0SX08
names: Similarity
messages: Belongs to the DtxR/MntR family.

645991:SGLY RS10500
gene id: 645991:SGLY_RS10500
uniprot id: F0T258
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

645991:SGLY RS10760
gene id: 645991:SGLY_RS10760
uniprot id: F0T2Q0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

645991:SGLY RS10925
gene id: 645991:SGLY_RS10925
uniprot id: F0T2T2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

645991:SGLY RS08205
gene id: 645991:SGLY_RS08205
uniprot id: F0SYB1
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS08310
gene id: 645991:SGLY_RS08310
uniprot id: F0SYD4
names: Similarity
messages: Belongs to the UPF0111 family.

645991:SGLY RS01130
gene id: 645991:SGLY_RS01130
uniprot id: F0SWA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS06060
gene id: 645991:SGLY_RS06060
uniprot id: F0SUN1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

645991:SGLY RS03235
gene id: 645991:SGLY_RS03235
uniprot id: F0SZX9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

645991:SGLY RS08765
gene id: 645991:SGLY_RS08765
uniprot id: F0SZH4
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

645991:SGLY RS02260
gene id: 645991:SGLY_RS02260
uniprot id: F0SY50
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS14740
gene id: 645991:SGLY_RS14740
uniprot id: F0SZN6
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS11405
gene id: 645991:SGLY_RS11405
uniprot id: F0SUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

645991:SGLY RS04400
gene id: 645991:SGLY_RS04400
uniprot id: F0T1V1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

645991:SGLY RS03265
gene id: 645991:SGLY_RS03265
uniprot id: F0SZY6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

645991:SGLY RS13870
gene id: 645991:SGLY_RS13870
uniprot id: F0SXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS04085
gene id: 645991:SGLY_RS04085
uniprot id: F0T191
names: Subcellular Location Annotation
messages: Periplasm

645991:SGLY RS03525
gene id: 645991:SGLY_RS03525
uniprot id: F0T0I4
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

645991:SGLY RS12345
gene id: 645991:SGLY_RS12345
uniprot id: F0SVH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

645991:SGLY RS12020
gene id: 645991:SGLY_RS12020
uniprot id: F0SUW8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS11305
gene id: 645991:SGLY_RS11305
uniprot id: F0SU16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

645991:SGLY RS01335
gene id: 645991:SGLY_RS01335
uniprot id: F0SWT1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645991:SGLY RS05625
gene id: 645991:SGLY_RS05625
uniprot id: F0SU57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

645991:SGLY RS11385
gene id: 645991:SGLY_RS11385
uniprot id: F0SUA5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS16090
gene id: 645991:SGLY_RS16090
uniprot id: F0T1Q4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

645991:SGLY RS01610
gene id: 645991:SGLY_RS01610
uniprot id: F0SXC4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

645991:SGLY RS09795
gene id: 645991:SGLY_RS09795
uniprot id: F0T0X5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

645991:SGLY RS09670
gene id: 645991:SGLY_RS09670
uniprot id: F0T0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

645991:SGLY RS01655
gene id: 645991:SGLY_RS01655
uniprot id: F0SXD1
names: Similarity
messages: Belongs to the peptidase S24 family.

645991:SGLY RS02115
gene id: 645991:SGLY_RS02115
uniprot id: F0SY20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

645991:SGLY RS12355
gene id: 645991:SGLY_RS12355
uniprot id: F0SVH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

645991:SGLY RS09405
gene id: 645991:SGLY_RS09405
uniprot id: F0T0A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

645991:SGLY RS12320
gene id: 645991:SGLY_RS12320
uniprot id: F0SVG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

645991:SGLY RS11435
gene id: 645991:SGLY_RS11435
uniprot id: F0SUB5
names: Similarity
messages: Belongs to the DprA/Smf family.

645991:SGLY RS15915
gene id: 645991:SGLY_RS15915
uniprot id: F0T1M0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS12510
gene id: 645991:SGLY_RS12510
uniprot id: F0SVZ1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

645991:SGLY RS14355
gene id: 645991:SGLY_RS14355
uniprot id: F0SZ13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645991:SGLY RS16465
gene id: 645991:SGLY_RS16465
uniprot id: F0T2C7
names: Similarity
messages: Belongs to the FBPase class 2 family.

645991:SGLY RS14555
gene id: 645991:SGLY_RS14555
uniprot id: F0SZ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

645991:SGLY RS14295
gene id: 645991:SGLY_RS14295
uniprot id: F0SYK7
names: Function
names: Subunit
messages: Hexamer of two alpha, two beta, and two delta chains.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.

645991:SGLY RS08820
gene id: 645991:SGLY_RS08820
uniprot id: F0SZI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

645991:SGLY RS16260
gene id: 645991:SGLY_RS16260
uniprot id: F0T286
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

645991:SGLY RS06715
gene id: 645991:SGLY_RS06715
uniprot id: F0SVU3
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS13030
gene id: 645991:SGLY_RS13030
uniprot id: F0SWN1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

645991:SGLY RS09480
gene id: 645991:SGLY_RS09480
uniprot id: F0T0R2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

645991:SGLY RS08540
gene id: 645991:SGLY_RS08540
uniprot id: F0SYX7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

645991:SGLY RS02320
gene id: 645991:SGLY_RS02320
uniprot id: F0SY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

645991:SGLY RS07150
gene id: 645991:SGLY_RS07150
uniprot id: F0SWG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

645991:SGLY RS11720
gene id: 645991:SGLY_RS11720
uniprot id: F0SUQ8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16375
gene id: 645991:SGLY_RS16375
uniprot id: F0T2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

645991:SGLY RS07855
gene id: 645991:SGLY_RS07855
uniprot id: F0SXP2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS03465
gene id: 645991:SGLY_RS03465
uniprot id: F0T026
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

645991:SGLY RS07455
gene id: 645991:SGLY_RS07455
uniprot id: F0SX10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

645991:SGLY RS16140
gene id: 645991:SGLY_RS16140
uniprot id: F0T1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

645991:SGLY RS11325
gene id: 645991:SGLY_RS11325
uniprot id: F0SU93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

645991:SGLY RS12950
gene id: 645991:SGLY_RS12950
uniprot id: F0SWL5
names: Similarity
messages: Belongs to the class-I fumarase family.

645991:SGLY RS11330
gene id: 645991:SGLY_RS11330
uniprot id: F0SU94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

645991:SGLY RS08180
gene id: 645991:SGLY_RS08180
uniprot id: F0SYA6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

645991:SGLY RS14135
gene id: 645991:SGLY_RS14135
uniprot id: F0SYH3
names: Similarity
messages: Belongs to the UPF0045 family.

645991:SGLY RS03695
gene id: 645991:SGLY_RS03695
uniprot id: F0T0L9
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

645991:SGLY RS05500
gene id: 645991:SGLY_RS05500
uniprot id: F0SU34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

645991:SGLY RS04995
gene id: 645991:SGLY_RS04995
uniprot id: F0T2L0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS10205
gene id: 645991:SGLY_RS10205
uniprot id: F0T1Z9
names: Similarity
messages: Belongs to the HypE family.

645991:SGLY RS06465
gene id: 645991:SGLY_RS06465
uniprot id: F0SV99
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

645991:SGLY RS06720
gene id: 645991:SGLY_RS06720
uniprot id: F0SVU4
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS00630
gene id: 645991:SGLY_RS00630
uniprot id: F0SVM0
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS11100
gene id: 645991:SGLY_RS11100
uniprot id: F0STY9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

645991:SGLY RS11560
gene id: 645991:SGLY_RS11560
uniprot id: F0SUE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

645991:SGLY RS11115
gene id: 645991:SGLY_RS11115
uniprot id: F0STZ2
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS02220
gene id: 645991:SGLY_RS02220
uniprot id: F0SY42
names: Similarity
messages: Belongs to the universal stress protein A family.

645991:SGLY RS04135
gene id: 645991:SGLY_RS04135
uniprot id: F0T1A1
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS14085
gene id: 645991:SGLY_RS14085
uniprot id: F0SYG2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-100 inactivates the nitrogenase reductase and regulates nitrogenase activity.

645991:SGLY RS00930
gene id: 645991:SGLY_RS00930
uniprot id: F0SW68
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

645991:SGLY RS12155
gene id: 645991:SGLY_RS12155
uniprot id: F0SVD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

645991:SGLY RS03595
gene id: 645991:SGLY_RS03595
uniprot id: F0T0J9
names: Similarity
messages: Belongs to the citrate synthase family.

645991:SGLY RS13715
gene id: 645991:SGLY_RS13715
uniprot id: F0SXU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

645991:SGLY RS05485
gene id: 645991:SGLY_RS05485
uniprot id: F0SU31
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

645991:SGLY RS07140
gene id: 645991:SGLY_RS07140
uniprot id: F0SWG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS02135
gene id: 645991:SGLY_RS02135
uniprot id: F0SY24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

645991:SGLY RS03350
gene id: 645991:SGLY_RS03350
uniprot id: F0T003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

645991:SGLY RS02055
gene id: 645991:SGLY_RS02055
uniprot id: F0SY08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

645991:SGLY RS12140
gene id: 645991:SGLY_RS12140
uniprot id: F0SVC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

645991:SGLY RS03665
gene id: 645991:SGLY_RS03665
uniprot id: F0T0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

645991:SGLY RS04575
gene id: 645991:SGLY_RS04575
uniprot id: F0T1Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

645991:SGLY RS14415
gene id: 645991:SGLY_RS14415
uniprot id: F0SZ24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS03430
gene id: 645991:SGLY_RS03430
uniprot id: F0T019
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

645991:SGLY RS02475
gene id: 645991:SGLY_RS02475
uniprot id: F0SYP1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS05740
gene id: 645991:SGLY_RS05740
uniprot id: F0SU80
names: Similarity
messages: Belongs to the DEAD box helicase family.

645991:SGLY RS00785
gene id: 645991:SGLY_RS00785
uniprot id: F0SVQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS14350
gene id: 645991:SGLY_RS14350
uniprot id: F0SZ12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

645991:SGLY RS14240
gene id: 645991:SGLY_RS14240
uniprot id: F0SYJ5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

645991:SGLY RS16605
gene id: 645991:SGLY_RS16605
uniprot id: F0T2U6
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS03030
gene id: 645991:SGLY_RS03030
uniprot id: F0SZE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

645991:SGLY RS16785
gene id: 645991:SGLY_RS16785
uniprot id: F0T2X8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

645991:SGLY RS11600
gene id: 645991:SGLY_RS11600
uniprot id: F0SUE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

645991:SGLY RS07525
gene id: 645991:SGLY_RS07525
uniprot id: F0SX25
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

645991:SGLY RS15595
gene id: 645991:SGLY_RS15595
uniprot id: F0T107
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

645991:SGLY RS00835
gene id: 645991:SGLY_RS00835
uniprot id: F0SW50
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

645991:SGLY RS11090
gene id: 645991:SGLY_RS11090
uniprot id: F0STY7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

645991:SGLY RS15485
gene id: 645991:SGLY_RS15485
uniprot id: F0T0Y6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

645991:SGLY RS10600
gene id: 645991:SGLY_RS10600
uniprot id: F0T2M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS02440
gene id: 645991:SGLY_RS02440
uniprot id: F0SYN4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

645991:SGLY RS01025
gene id: 645991:SGLY_RS01025
uniprot id: F0SW88
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

645991:SGLY RS15435
gene id: 645991:SGLY_RS15435
uniprot id: F0T0H5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

645991:SGLY RS12600
gene id: 645991:SGLY_RS12600
uniprot id: F0SW08
names: Similarity
messages: Belongs to the UPF0251 family.

645991:SGLY RS14170
gene id: 645991:SGLY_RS14170
uniprot id: F0SYI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS11140
gene id: 645991:SGLY_RS11140
uniprot id: F0STZ7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS13575
gene id: 645991:SGLY_RS13575
uniprot id: F0SXB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS10255
gene id: 645991:SGLY_RS10255
uniprot id: F0T209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

645991:SGLY RS10445
gene id: 645991:SGLY_RS10445
uniprot id: F0T247
names: Similarity
messages: Belongs to the thioredoxin family.

645991:SGLY RS03660
gene id: 645991:SGLY_RS03660
uniprot id: F0T0L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

645991:SGLY RS06790
gene id: 645991:SGLY_RS06790
uniprot id: F0SVV7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS17250
gene id: 645991:SGLY_RS17250
uniprot id: F0SZ51
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

645991:SGLY RS03645
gene id: 645991:SGLY_RS03645
uniprot id: F0T0K9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

645991:SGLY RS15880
gene id: 645991:SGLY_RS15880
uniprot id: F0T1L2
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

645991:SGLY RS10715
gene id: 645991:SGLY_RS10715
uniprot id: F0T2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

645991:SGLY RS11830
gene id: 645991:SGLY_RS11830
uniprot id: F0SUT0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

645991:SGLY RS02180
gene id: 645991:SGLY_RS02180
uniprot id: F0SY34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

645991:SGLY RS11505
gene id: 645991:SGLY_RS11505
uniprot id: F0SUC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

645991:SGLY RS10455
gene id: 645991:SGLY_RS10455
uniprot id: F0T249
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

645991:SGLY RS10710
gene id: 645991:SGLY_RS10710
uniprot id: F0T2P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

645991:SGLY RS09360
gene id: 645991:SGLY_RS09360
uniprot id: F0T091
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

645991:SGLY RS04925
gene id: 645991:SGLY_RS04925
uniprot id: F0T2J6
names: Similarity
messages: Belongs to the CdaR family.

645991:SGLY RS09730
gene id: 645991:SGLY_RS09730
uniprot id: F0T0W3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

645991:SGLY RS12660
gene id: 645991:SGLY_RS12660
uniprot id: F0SW19
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

645991:SGLY RS08885
gene id: 645991:SGLY_RS08885
uniprot id: F0SZJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS14990
gene id: 645991:SGLY_RS14990
uniprot id: F0SZT8
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS17075
gene id: 645991:SGLY_RS17075
uniprot id: F0SVR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

645991:SGLY RS15510
gene id: 645991:SGLY_RS15510
uniprot id: F0T0Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS13720
gene id: 645991:SGLY_RS13720
uniprot id: F0SXU5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

645991:SGLY RS01485
gene id: 645991:SGLY_RS01485
uniprot id: F0SWV5
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS00655
gene id: 645991:SGLY_RS00655
uniprot id: F0SVM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

645991:SGLY RS06660
gene id: 645991:SGLY_RS06660
uniprot id: F0SVT2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS03190
gene id: 645991:SGLY_RS03190
uniprot id: F0SZX1
names: Similarity
messages: Belongs to the FlgD family.

645991:SGLY RS11420
gene id: 645991:SGLY_RS11420
uniprot id: F0SUB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

645991:SGLY RS16385
gene id: 645991:SGLY_RS16385
uniprot id: F0T2B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645991:SGLY RS01205
gene id: 645991:SGLY_RS01205
uniprot id: F0SWB9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS06655
gene id: 645991:SGLY_RS06655
uniprot id: F0SVT1
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS11380
gene id: 645991:SGLY_RS11380
uniprot id: F0SUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

645991:SGLY RS09345
gene id: 645991:SGLY_RS09345
uniprot id: F0T088
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS09040
gene id: 645991:SGLY_RS09040
uniprot id: F0SZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS12930
gene id: 645991:SGLY_RS12930
uniprot id: F0SWL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

645991:SGLY RS12415
gene id: 645991:SGLY_RS12415
uniprot id: F0SVI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

645991:SGLY RS05575
gene id: 645991:SGLY_RS05575
uniprot id: F0SU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS02095
gene id: 645991:SGLY_RS02095
uniprot id: F0SY16
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

645991:SGLY RS03360
gene id: 645991:SGLY_RS03360
uniprot id: F0T005
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

645991:SGLY RS01070
gene id: 645991:SGLY_RS01070
uniprot id: F0SW97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

645991:SGLY RS11055
gene id: 645991:SGLY_RS11055
uniprot id: F0STY4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

645991:SGLY RS10560
gene id: 645991:SGLY_RS10560
uniprot id: F0T270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

645991:SGLY RS03195
gene id: 645991:SGLY_RS03195
uniprot id: F0SZX2
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

645991:SGLY RS11670
gene id: 645991:SGLY_RS11670
uniprot id: F0SUG3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

645991:SGLY RS08605
gene id: 645991:SGLY_RS08605
uniprot id: F0SYY9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

645991:SGLY RS03135
gene id: 645991:SGLY_RS03135
uniprot id: F0SZW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

645991:SGLY RS01580
gene id: 645991:SGLY_RS01580
uniprot id: F0SWX4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

645991:SGLY RS12925
gene id: 645991:SGLY_RS12925
uniprot id: F0SWL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

645991:SGLY RS01300
gene id: 645991:SGLY_RS01300
uniprot id: F0SWS4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS11815
gene id: 645991:SGLY_RS11815
uniprot id: F0SUS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

645991:SGLY RS10310
gene id: 645991:SGLY_RS10310
uniprot id: F0T220
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS14535
gene id: 645991:SGLY_RS14535
uniprot id: F0SZ48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

645991:SGLY RS00850
gene id: 645991:SGLY_RS00850
uniprot id: F0SW53
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

645991:SGLY RS03320
gene id: 645991:SGLY_RS03320
uniprot id: F0SZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

645991:SGLY RS06430
gene id: 645991:SGLY_RS06430
uniprot id: F0SV90
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

645991:SGLY RS03470
gene id: 645991:SGLY_RS03470
uniprot id: F0T027
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

645991:SGLY RS10225
gene id: 645991:SGLY_RS10225
uniprot id: F0T203
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

645991:SGLY RS08185
gene id: 645991:SGLY_RS08185
uniprot id: F0SYA7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS11035
gene id: 645991:SGLY_RS11035
uniprot id: F0STY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

645991:SGLY RS09965
gene id: 645991:SGLY_RS09965
uniprot id: F0T1F4
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS16445
gene id: 645991:SGLY_RS16445
uniprot id: F0T2C3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

645991:SGLY RS09300
gene id: 645991:SGLY_RS09300
uniprot id: F0T079
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

645991:SGLY RS02305
gene id: 645991:SGLY_RS02305
uniprot id: F0SY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

645991:SGLY RS16860
gene id: 645991:SGLY_RS16860
uniprot id: F0T2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

645991:SGLY RS03110
gene id: 645991:SGLY_RS03110
uniprot id: F0SZG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

645991:SGLY RS08035
gene id: 645991:SGLY_RS08035
uniprot id: F0SV43
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

645991:SGLY RS16070
gene id: 645991:SGLY_RS16070
uniprot id: F0T1Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

645991:SGLY RS10235
gene id: 645991:SGLY_RS10235
uniprot id: F0T205
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

645991:SGLY RS05445
gene id: 645991:SGLY_RS05445
uniprot id: F0SU22
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

645991:SGLY RS09180
gene id: 645991:SGLY_RS09180
uniprot id: F0T055
names: Similarity
messages: Belongs to the UxaA family.

645991:SGLY RS11835
gene id: 645991:SGLY_RS11835
uniprot id: F0SUT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

645991:SGLY RS03125
gene id: 645991:SGLY_RS03125
uniprot id: F0SZV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

645991:SGLY RS09720
gene id: 645991:SGLY_RS09720
uniprot id: F0T0W1
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

645991:SGLY RS08330
gene id: 645991:SGLY_RS08330
uniprot id: F0SYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

645991:SGLY RS04340
gene id: 645991:SGLY_RS04340
uniprot id: F0T1U0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS16825
gene id: 645991:SGLY_RS16825
uniprot id: F0T2Y6
names: Similarity
messages: Belongs to the ParB family.

645991:SGLY RS13930
gene id: 645991:SGLY_RS13930
uniprot id: F0SXY4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

645991:SGLY RS09775
gene id: 645991:SGLY_RS09775
uniprot id: F0T0X2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

645991:SGLY RS02190
gene id: 645991:SGLY_RS02190
uniprot id: F0SY36
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

645991:SGLY RS02195
gene id: 645991:SGLY_RS02195
uniprot id: F0SY37
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS08110
gene id: 645991:SGLY_RS08110
uniprot id: F0SY92
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

645991:SGLY RS04950
gene id: 645991:SGLY_RS04950
uniprot id: F0T2K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

645991:SGLY RS14540
gene id: 645991:SGLY_RS14540
uniprot id: F0SZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

645991:SGLY RS09710
gene id: 645991:SGLY_RS09710
uniprot id: F0T0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

645991:SGLY RS13455
gene id: 645991:SGLY_RS13455
uniprot id: F0SX93
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

645991:SGLY RS13880
gene id: 645991:SGLY_RS13880
uniprot id: F0SXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS11545
gene id: 645991:SGLY_RS11545
uniprot id: F0SUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

645991:SGLY RS02205
gene id: 645991:SGLY_RS02205
uniprot id: F0SY39
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

645991:SGLY RS02140
gene id: 645991:SGLY_RS02140
uniprot id: F0SY25
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

645991:SGLY RS02410
gene id: 645991:SGLY_RS02410
uniprot id: F0SYM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS11290
gene id: 645991:SGLY_RS11290
uniprot id: F0SU13
names: Similarity
messages: Belongs to the ribF family.

645991:SGLY RS04125
gene id: 645991:SGLY_RS04125
uniprot id: F0T199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

645991:SGLY RS03130
gene id: 645991:SGLY_RS03130
uniprot id: F0SZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

645991:SGLY RS16745
gene id: 645991:SGLY_RS16745
uniprot id: F0T2X0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

645991:SGLY RS08325
gene id: 645991:SGLY_RS08325
uniprot id: F0SYD7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

645991:SGLY RS03685
gene id: 645991:SGLY_RS03685
uniprot id: F0T0L7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

645991:SGLY RS02565
gene id: 645991:SGLY_RS02565
uniprot id: F0SYQ7
names: Subcellular Location Annotation
messages: Membrane

645991:SGLY RS13690
gene id: 645991:SGLY_RS13690
uniprot id: F0SXT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

645991:SGLY RS03480
gene id: 645991:SGLY_RS03480
uniprot id: F0T029
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS13295
gene id: 645991:SGLY_RS13295
uniprot id: F0SX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

645991:SGLY RS10555
gene id: 645991:SGLY_RS10555
uniprot id: F0T269
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

645991:SGLY RS15155
gene id: 645991:SGLY_RS15155
uniprot id: F0T0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

645991:SGLY RS03570
gene id: 645991:SGLY_RS03570
uniprot id: F0T0J3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

645991:SGLY RS04605
gene id: 645991:SGLY_RS04605
uniprot id: F0T1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

645991:SGLY RS14490
gene id: 645991:SGLY_RS14490
uniprot id: F0SZ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

645991:SGLY RS11065
gene id: 645991:SGLY_RS11065
uniprot id: F0STY6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

645991:SGLY RS05745
gene id: 645991:SGLY_RS05745
uniprot id: F0SU81
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

645991:SGLY RS13570
gene id: 645991:SGLY_RS13570
uniprot id: F0SXB6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

645991:SGLY RS11355
gene id: 645991:SGLY_RS11355
uniprot id: F0SU99
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

645991:SGLY RS01000
gene id: 645991:SGLY_RS01000
uniprot id: F0SW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

645991:SGLY RS02065
gene id: 645991:SGLY_RS02065
uniprot id: F0SY10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

645991:SGLY RS15290
gene id: 645991:SGLY_RS15290
uniprot id: F0T0E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

645991:SGLY RS08790
gene id: 645991:SGLY_RS08790
uniprot id: F0SZH9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

645991:SGLY RS10065
gene id: 645991:SGLY_RS10065
uniprot id: F0T1H4
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

645991:SGLY RS02605
gene id: 645991:SGLY_RS02605
uniprot id: F0SYR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

645991:SGLY RS05145
gene id: 645991:SGLY_RS05145
uniprot id: F0STR3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

645991:SGLY RS05140
gene id: 645991:SGLY_RS05140
uniprot id: F0STR2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

645991:SGLY RS02080
gene id: 645991:SGLY_RS02080
uniprot id: F0SY13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

645991:SGLY RS07110
gene id: 645991:SGLY_RS07110
uniprot id: F0SWF8
names: Similarity
messages: Belongs to the UPF0251 family.

645991:SGLY RS07510
gene id: 645991:SGLY_RS07510
uniprot id: F0SX21
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

645991:SGLY RS09185
gene id: 645991:SGLY_RS09185
uniprot id: F0T056
names: Similarity
messages: Belongs to the asparagine synthetase family.

645991:SGLY RS00790
gene id: 645991:SGLY_RS00790
uniprot id: F0SVQ1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

645991:SGLY RS14440
gene id: 645991:SGLY_RS14440
uniprot id: F0SZ29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

645991:SGLY RS12055
gene id: 645991:SGLY_RS12055
uniprot id: F0SUX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

645991:SGLY RS14125
gene id: 645991:SGLY_RS14125
uniprot id: F0SYH1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

645991:SGLY RS00810
gene id: 645991:SGLY_RS00810
uniprot id: F0SVQ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.