644966:TMAR RS01210
gene id: 644966:TMAR_RS01210
uniprot id: E6SM14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS08810
gene id: 644966:TMAR_RS08810
uniprot id: E6SHX3
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

644966:TMAR RS00815
gene id: 644966:TMAR_RS00815
uniprot id: E6SLK2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

644966:TMAR RS11095
gene id: 644966:TMAR_RS11095
uniprot id: E6SKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

644966:TMAR RS14645
gene id: 644966:TMAR_RS14645
uniprot id: E6SJS3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

644966:TMAR RS09905
gene id: 644966:TMAR_RS09905
uniprot id: E6SJ50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

644966:TMAR RS06045
gene id: 644966:TMAR_RS06045
uniprot id: E6SL68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

644966:TMAR RS02435
gene id: 644966:TMAR_RS02435
uniprot id: E6SGP1
names: Similarity
messages: Belongs to the peptidase C56 family.

644966:TMAR RS02080
gene id: 644966:TMAR_RS02080
uniprot id: E6SGA1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644966:TMAR RS04965
gene id: 644966:TMAR_RS04965
uniprot id: E6SJM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

644966:TMAR RS11195
gene id: 644966:TMAR_RS11195
uniprot id: E6SKU4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

644966:TMAR RS03900
gene id: 644966:TMAR_RS03900
uniprot id: E6SIH1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

644966:TMAR RS05830
gene id: 644966:TMAR_RS05830
uniprot id: E6SKP8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

644966:TMAR RS09075
gene id: 644966:TMAR_RS09075
uniprot id: E6SI98
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

644966:TMAR RS05415
gene id: 644966:TMAR_RS05415
uniprot id: E6SK33
names: Similarity
messages: Belongs to the CinA family.

644966:TMAR RS07095
gene id: 644966:TMAR_RS07095
uniprot id: E6SML5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

644966:TMAR RS11040
gene id: 644966:TMAR_RS11040
uniprot id: E6SKD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

644966:TMAR RS02240
gene id: 644966:TMAR_RS02240
uniprot id: E6SGK4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

644966:TMAR RS02105
gene id: 644966:TMAR_RS02105
uniprot id: E6SGA6
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS00650
gene id: 644966:TMAR_RS00650
uniprot id: E6SL39
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

644966:TMAR RS11615
gene id: 644966:TMAR_RS11615
uniprot id: E6SLF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS09120
gene id: 644966:TMAR_RS09120
uniprot id: E6SIA7
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

644966:TMAR RS06200
gene id: 644966:TMAR_RS06200
uniprot id: E6SL99
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

644966:TMAR RS03735
gene id: 644966:TMAR_RS03735
uniprot id: E6SI66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

644966:TMAR RS03905
gene id: 644966:TMAR_RS03905
uniprot id: E6SIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS08945
gene id: 644966:TMAR_RS08945
uniprot id: E6SI03
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

644966:TMAR RS04335
gene id: 644966:TMAR_RS04335
uniprot id: E6SIW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

644966:TMAR RS06725
gene id: 644966:TMAR_RS06725
uniprot id: E6SM74
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS05915
gene id: 644966:TMAR_RS05915
uniprot id: E6SKR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

644966:TMAR RS09955
gene id: 644966:TMAR_RS09955
uniprot id: E6SJ61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

644966:TMAR RS11890
gene id: 644966:TMAR_RS11890
uniprot id: E6SLY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

644966:TMAR RS01145
gene id: 644966:TMAR_RS01145
uniprot id: E6SM01
names: Similarity
messages: Belongs to the peptidase S41A family.

644966:TMAR RS14650
gene id: 644966:TMAR_RS14650
uniprot id: E6SK25
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

644966:TMAR RS07525
gene id: 644966:TMAR_RS07525
uniprot id: E6SGE2
names: Similarity
messages: Belongs to the CdaR family.

644966:TMAR RS04435
gene id: 644966:TMAR_RS04435
uniprot id: E6SIY3
names: Similarity
messages: Belongs to the transpeptidase family.

644966:TMAR RS06795
gene id: 644966:TMAR_RS06795
uniprot id: E6SM88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

644966:TMAR RS09035
gene id: 644966:TMAR_RS09035
uniprot id: E6SI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS13810
gene id: 644966:TMAR_RS13810
uniprot id: E6SGX9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

644966:TMAR RS11180
gene id: 644966:TMAR_RS11180
uniprot id: E6SKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

644966:TMAR RS11530
gene id: 644966:TMAR_RS11530
uniprot id: E6SLE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

644966:TMAR RS06370
gene id: 644966:TMAR_RS06370
uniprot id: E6SLR5
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

644966:TMAR RS04515
gene id: 644966:TMAR_RS04515
uniprot id: E6SIZ8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

644966:TMAR RS11455
gene id: 644966:TMAR_RS11455
uniprot id: E6SLC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

644966:TMAR RS04255
gene id: 644966:TMAR_RS04255
uniprot id: E6SIU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

644966:TMAR RS10180
gene id: 644966:TMAR_RS10180
uniprot id: E6SJH6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

644966:TMAR RS10970
gene id: 644966:TMAR_RS10970
uniprot id: E6SKC3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

644966:TMAR RS11895
gene id: 644966:TMAR_RS11895
uniprot id: E6SLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

644966:TMAR RS11650
gene id: 644966:TMAR_RS11650
uniprot id: E6SLF9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

644966:TMAR RS11400
gene id: 644966:TMAR_RS11400
uniprot id: E6SKY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

644966:TMAR RS02440
gene id: 644966:TMAR_RS02440
uniprot id: E6SGP2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

644966:TMAR RS03770
gene id: 644966:TMAR_RS03770
uniprot id: E6SI73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS02540
gene id: 644966:TMAR_RS02540
uniprot id: E6SGX7
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS08370
gene id: 644966:TMAR_RS08370
uniprot id: E6SH98
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

644966:TMAR RS00865
gene id: 644966:TMAR_RS00865
uniprot id: E6SLK7
names: Similarity
messages: Belongs to the peptidase S8 family.

644966:TMAR RS02715
gene id: 644966:TMAR_RS02715
uniprot id: E6SH15
names: Similarity
messages: Belongs to the FemABX family.

644966:TMAR RS09190
gene id: 644966:TMAR_RS09190
uniprot id: E6SIB9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

644966:TMAR RS09255
gene id: 644966:TMAR_RS09255
uniprot id: E6SID3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

644966:TMAR RS01560
gene id: 644966:TMAR_RS01560
uniprot id: E6SMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS03225
gene id: 644966:TMAR_RS03225
uniprot id: E6SHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS10440
gene id: 644966:TMAR_RS10440
uniprot id: E6SJU7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

644966:TMAR RS03600
gene id: 644966:TMAR_RS03600
uniprot id: E6SI40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

644966:TMAR RS08375
gene id: 644966:TMAR_RS08375
uniprot id: E6SH99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

644966:TMAR RS02675
gene id: 644966:TMAR_RS02675
uniprot id: E6SH06
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

644966:TMAR RS00485
gene id: 644966:TMAR_RS00485
uniprot id: E6SL06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS01465
gene id: 644966:TMAR_RS01465
uniprot id: E6SM64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

644966:TMAR RS01135
gene id: 644966:TMAR_RS01135
uniprot id: E6SLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

644966:TMAR RS06520
gene id: 644966:TMAR_RS06520
uniprot id: E6SLU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

644966:TMAR RS08470
gene id: 644966:TMAR_RS08470
uniprot id: E6SHI7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

644966:TMAR RS05510
gene id: 644966:TMAR_RS05510
uniprot id: E6SK52
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

644966:TMAR RS05845
gene id: 644966:TMAR_RS05845
uniprot id: E6SKQ1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

644966:TMAR RS07770
gene id: 644966:TMAR_RS07770
uniprot id: E6SGQ5
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

644966:TMAR RS10420
gene id: 644966:TMAR_RS10420
uniprot id: E6SJU3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS05610
gene id: 644966:TMAR_RS05610
uniprot id: E6SK72
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

644966:TMAR RS07960
gene id: 644966:TMAR_RS07960
uniprot id: E6SGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05130
gene id: 644966:TMAR_RS05130
uniprot id: E6SJQ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

644966:TMAR RS12265
gene id: 644966:TMAR_RS12265
uniprot id: E6SMR2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

644966:TMAR RS10935
gene id: 644966:TMAR_RS10935
uniprot id: E6SKB7
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS04610
gene id: 644966:TMAR_RS04610
uniprot id: E6SJ84
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

644966:TMAR RS01615
gene id: 644966:TMAR_RS01615
uniprot id: E6SMG5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

644966:TMAR RS10780
gene id: 644966:TMAR_RS10780
uniprot id: E6SK87
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

644966:TMAR RS09860
gene id: 644966:TMAR_RS09860
uniprot id: E6SJ42
names: Similarity
messages: Belongs to the CapA family.

644966:TMAR RS03095
gene id: 644966:TMAR_RS03095
uniprot id: E6SHF8
names: Similarity
messages: Belongs to the EamA transporter family.

644966:TMAR RS11225
gene id: 644966:TMAR_RS11225
uniprot id: E6SKV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

644966:TMAR RS09730
gene id: 644966:TMAR_RS09730
uniprot id: E6SJ14
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS04770
gene id: 644966:TMAR_RS04770
uniprot id: E6SJB6
names: Subcellular Location Annotation
messages: Cell membrane

644966:TMAR RS04890
gene id: 644966:TMAR_RS04890
uniprot id: E6SJE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

644966:TMAR RS01695
gene id: 644966:TMAR_RS01695
uniprot id: E6SMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

644966:TMAR RS04875
gene id: 644966:TMAR_RS04875
uniprot id: E6SJD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

644966:TMAR RS07675
gene id: 644966:TMAR_RS07675
uniprot id: E6SGG8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

644966:TMAR RS02120
gene id: 644966:TMAR_RS02120
uniprot id: E6SGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

644966:TMAR RS01385
gene id: 644966:TMAR_RS01385
uniprot id: E6SM48
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

644966:TMAR RS13730
gene id: 644966:TMAR_RS13730
uniprot id: E6SH60
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS01680
gene id: 644966:TMAR_RS01680
uniprot id: E6SMH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

644966:TMAR RS11840
gene id: 644966:TMAR_RS11840
uniprot id: E6SLX9
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS05650
gene id: 644966:TMAR_RS05650
uniprot id: E6SKL2
names: Similarity
messages: Belongs to the ketopantoate reductase family.

644966:TMAR RS00415
gene id: 644966:TMAR_RS00415
uniprot id: E6SL00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

644966:TMAR RS11535
gene id: 644966:TMAR_RS11535
uniprot id: E6SLE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

644966:TMAR RS10185
gene id: 644966:TMAR_RS10185
uniprot id: E6SJH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

644966:TMAR RS01100
gene id: 644966:TMAR_RS01100
uniprot id: E6SLQ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

644966:TMAR RS04585
gene id: 644966:TMAR_RS04585
uniprot id: E6SJ12
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

644966:TMAR RS02130
gene id: 644966:TMAR_RS02130
uniprot id: E6SGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS04835
gene id: 644966:TMAR_RS04835
uniprot id: E6SJC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

644966:TMAR RS01505
gene id: 644966:TMAR_RS01505
uniprot id: E6SME2
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

644966:TMAR RS03985
gene id: 644966:TMAR_RS03985
uniprot id: E6SII8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

644966:TMAR RS05350
gene id: 644966:TMAR_RS05350
uniprot id: E6SK20
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

644966:TMAR RS01640
gene id: 644966:TMAR_RS01640
uniprot id: E6SMH0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

644966:TMAR RS06715
gene id: 644966:TMAR_RS06715
uniprot id: E6SM72
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS11230
gene id: 644966:TMAR_RS11230
uniprot id: E6SKV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

644966:TMAR RS10805
gene id: 644966:TMAR_RS10805
uniprot id: E6SK92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

644966:TMAR RS01105
gene id: 644966:TMAR_RS01105
uniprot id: E6SLQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

644966:TMAR RS08615
gene id: 644966:TMAR_RS08615
uniprot id: E6SHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS08300
gene id: 644966:TMAR_RS08300
uniprot id: E6SH84
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

644966:TMAR RS09885
gene id: 644966:TMAR_RS09885
uniprot id: E6SJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS09720
gene id: 644966:TMAR_RS09720
uniprot id: E6SIU2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

644966:TMAR RS03175
gene id: 644966:TMAR_RS03175
uniprot id: E6SHP0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644966:TMAR RS08445
gene id: 644966:TMAR_RS08445
uniprot id: E6SHI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

644966:TMAR RS12195
gene id: 644966:TMAR_RS12195
uniprot id: E6SK35
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

644966:TMAR RS02015
gene id: 644966:TMAR_RS02015
uniprot id: E6SG91
names: Similarity
messages: Belongs to the Nudix hydrolase family.

644966:TMAR RS05320
gene id: 644966:TMAR_RS05320
uniprot id: E6SK13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

644966:TMAR RS02405
gene id: 644966:TMAR_RS02405
uniprot id: E6SGN5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

644966:TMAR RS00560
gene id: 644966:TMAR_RS00560
uniprot id: E6SL22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

644966:TMAR RS03530
gene id: 644966:TMAR_RS03530
uniprot id: E6SI27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644966:TMAR RS05410
gene id: 644966:TMAR_RS05410
uniprot id: E6SK32
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

644966:TMAR RS00015
gene id: 644966:TMAR_RS00015
uniprot id: E6SK04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

644966:TMAR RS08095
gene id: 644966:TMAR_RS08095
uniprot id: E6SH42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05440
gene id: 644966:TMAR_RS05440
uniprot id: E6SK38
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

644966:TMAR RS06205
gene id: 644966:TMAR_RS06205
uniprot id: E6SLA0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

644966:TMAR RS08725
gene id: 644966:TMAR_RS08725
uniprot id: E6SHV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS01280
gene id: 644966:TMAR_RS01280
uniprot id: E6SM27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

644966:TMAR RS03195
gene id: 644966:TMAR_RS03195
uniprot id: E6SHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

644966:TMAR RS03040
gene id: 644966:TMAR_RS03040
uniprot id: E6SHE7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

644966:TMAR RS01935
gene id: 644966:TMAR_RS01935
uniprot id: E6SG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS03065
gene id: 644966:TMAR_RS03065
uniprot id: E6SHF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

644966:TMAR RS03050
gene id: 644966:TMAR_RS03050
uniprot id: E6SHE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

644966:TMAR RS11085
gene id: 644966:TMAR_RS11085
uniprot id: E6SKT0
names: Similarity
messages: Belongs to the peptidase S16 family.

644966:TMAR RS02125
gene id: 644966:TMAR_RS02125
uniprot id: E6SGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05550
gene id: 644966:TMAR_RS05550
uniprot id: E6SK60
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

644966:TMAR RS09340
gene id: 644966:TMAR_RS09340
uniprot id: E6SIF2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644966:TMAR RS05165
gene id: 644966:TMAR_RS05165
uniprot id: E6SJR0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS06355
gene id: 644966:TMAR_RS06355
uniprot id: E6SLR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

644966:TMAR RS11385
gene id: 644966:TMAR_RS11385
uniprot id: E6SKY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

644966:TMAR RS14405
gene id: 644966:TMAR_RS14405
uniprot id: E6SHW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

644966:TMAR RS11315
gene id: 644966:TMAR_RS11315
uniprot id: E6SKW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

644966:TMAR RS01415
gene id: 644966:TMAR_RS01415
uniprot id: E6SM54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

644966:TMAR RS01670
gene id: 644966:TMAR_RS01670
uniprot id: E6SMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

644966:TMAR RS02840
gene id: 644966:TMAR_RS02840
uniprot id: E6SHA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS08910
gene id: 644966:TMAR_RS08910
uniprot id: E6SHZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

644966:TMAR RS01540
gene id: 644966:TMAR_RS01540
uniprot id: E6SMF0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

644966:TMAR RS03320
gene id: 644966:TMAR_RS03320
uniprot id: E6SHR8
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS08550
gene id: 644966:TMAR_RS08550
uniprot id: E6SHK6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

644966:TMAR RS06875
gene id: 644966:TMAR_RS06875
uniprot id: E6SMA4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

644966:TMAR RS03635
gene id: 644966:TMAR_RS03635
uniprot id: E6SI48
names: Similarity
messages: Belongs to the creatininase superfamily.

644966:TMAR RS04980
gene id: 644966:TMAR_RS04980
uniprot id: E6SJM3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

644966:TMAR RS01555
gene id: 644966:TMAR_RS01555
uniprot id: E6SMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS08520
gene id: 644966:TMAR_RS08520
uniprot id: E6SHK0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

644966:TMAR RS05775
gene id: 644966:TMAR_RS05775
uniprot id: E6SKN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

644966:TMAR RS07920
gene id: 644966:TMAR_RS07920
uniprot id: E6SGT7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

644966:TMAR RS06320
gene id: 644966:TMAR_RS06320
uniprot id: E6SLC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

644966:TMAR RS09140
gene id: 644966:TMAR_RS09140
uniprot id: E6SIB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

644966:TMAR RS02045
gene id: 644966:TMAR_RS02045
uniprot id: E6SG96
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644966:TMAR RS04525
gene id: 644966:TMAR_RS04525
uniprot id: E6SJ00
names: Similarity
messages: Belongs to the YggT family.

644966:TMAR RS09760
gene id: 644966:TMAR_RS09760
uniprot id: E6SJ20
names: Subcellular Location Annotation
messages: Mitochondrion

644966:TMAR RS13985
gene id: 644966:TMAR_RS13985
uniprot id: E6SM28
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

644966:TMAR RS12230
gene id: 644966:TMAR_RS12230
uniprot id: E6SLT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

644966:TMAR RS04310
gene id: 644966:TMAR_RS04310
uniprot id: E6SIV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

644966:TMAR RS09900
gene id: 644966:TMAR_RS09900
uniprot id: E6SJ49
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

644966:TMAR RS08770
gene id: 644966:TMAR_RS08770
uniprot id: E6SHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

644966:TMAR RS06535
gene id: 644966:TMAR_RS06535
uniprot id: E6SLU6
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

644966:TMAR RS02885
gene id: 644966:TMAR_RS02885
uniprot id: E6SHB6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS06150
gene id: 644966:TMAR_RS06150
uniprot id: E6SL89
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS00710
gene id: 644966:TMAR_RS00710
uniprot id: E6SL47
names: Similarity
messages: Belongs to the EamA transporter family.

644966:TMAR RS05715
gene id: 644966:TMAR_RS05715
uniprot id: E6SKM5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

644966:TMAR RS04940
gene id: 644966:TMAR_RS04940
uniprot id: E6SJL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

644966:TMAR RS08855
gene id: 644966:TMAR_RS08855
uniprot id: E6SHY5
names: Similarity
messages: Belongs to the UPF0173 family.

644966:TMAR RS05075
gene id: 644966:TMAR_RS05075
uniprot id: E6SJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

644966:TMAR RS10710
gene id: 644966:TMAR_RS10710
uniprot id: E6SJZ8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

644966:TMAR RS08410
gene id: 644966:TMAR_RS08410
uniprot id: E6SHH5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

644966:TMAR RS00950
gene id: 644966:TMAR_RS00950
uniprot id: E6SLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

644966:TMAR RS00350
gene id: 644966:TMAR_RS00350
uniprot id: E6SKK5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

644966:TMAR RS04725
gene id: 644966:TMAR_RS04725
uniprot id: E6SJA7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

644966:TMAR RS03235
gene id: 644966:TMAR_RS03235
uniprot id: E6SHQ2
names: Similarity
messages: Belongs to the UPF0312 family.

644966:TMAR RS04480
gene id: 644966:TMAR_RS04480
uniprot id: E6SIZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

644966:TMAR RS11360
gene id: 644966:TMAR_RS11360
uniprot id: E6SKX6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

644966:TMAR RS08090
gene id: 644966:TMAR_RS08090
uniprot id: E6SH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

644966:TMAR RS03540
gene id: 644966:TMAR_RS03540
uniprot id: E6SI29
names: Similarity
messages: Belongs to the MotB family.

644966:TMAR RS08430
gene id: 644966:TMAR_RS08430
uniprot id: E6SHH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

644966:TMAR RS06720
gene id: 644966:TMAR_RS06720
uniprot id: E6SM73
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS08915
gene id: 644966:TMAR_RS08915
uniprot id: E6SHZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

644966:TMAR RS06515
gene id: 644966:TMAR_RS06515
uniprot id: E6SLU2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

644966:TMAR RS05525
gene id: 644966:TMAR_RS05525
uniprot id: E6SK55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

644966:TMAR RS03035
gene id: 644966:TMAR_RS03035
uniprot id: E6SHE6
names: Cofactor
messages: Binds 1 FAD per subunit.

644966:TMAR RS01730
gene id: 644966:TMAR_RS01730
uniprot id: E6SMI9
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS05295
gene id: 644966:TMAR_RS05295
uniprot id: E6SK08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

644966:TMAR RS06475
gene id: 644966:TMAR_RS06475
uniprot id: E6SLT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

644966:TMAR RS00295
gene id: 644966:TMAR_RS00295
uniprot id: E6SKJ5
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS08045
gene id: 644966:TMAR_RS08045
uniprot id: E6SGW2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS08295
gene id: 644966:TMAR_RS08295
uniprot id: E6SH83
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

644966:TMAR RS00940
gene id: 644966:TMAR_RS00940
uniprot id: E6SLM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644966:TMAR RS11405
gene id: 644966:TMAR_RS11405
uniprot id: E6SKY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

644966:TMAR RS07485
gene id: 644966:TMAR_RS07485
uniprot id: E6SGD4
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS02000
gene id: 644966:TMAR_RS02000
uniprot id: E6SG88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

644966:TMAR RS06350
gene id: 644966:TMAR_RS06350
uniprot id: E6SLR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

644966:TMAR RS02800
gene id: 644966:TMAR_RS02800
uniprot id: E6SH32
names: Similarity
messages: Belongs to the peptidase S58 family.

644966:TMAR RS03885
gene id: 644966:TMAR_RS03885
uniprot id: E6SIG8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

644966:TMAR RS04235
gene id: 644966:TMAR_RS04235
uniprot id: E6SIU4
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS08640
gene id: 644966:TMAR_RS08640
uniprot id: E6SHM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

644966:TMAR RS01345
gene id: 644966:TMAR_RS01345
uniprot id: E6SM40
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

644966:TMAR RS02165
gene id: 644966:TMAR_RS02165
uniprot id: E6SGI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

644966:TMAR RS09930
gene id: 644966:TMAR_RS09930
uniprot id: E6SJ56
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

644966:TMAR RS05825
gene id: 644966:TMAR_RS05825
uniprot id: E6SKP7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

644966:TMAR RS07030
gene id: 644966:TMAR_RS07030
uniprot id: E6SMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

644966:TMAR RS05400
gene id: 644966:TMAR_RS05400
uniprot id: E6SK30
names: Similarity
messages: Belongs to the IMPACT family.

644966:TMAR RS11690
gene id: 644966:TMAR_RS11690
uniprot id: E6SLG7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

644966:TMAR RS06555
gene id: 644966:TMAR_RS06555
uniprot id: E6SLV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

644966:TMAR RS00390
gene id: 644966:TMAR_RS00390
uniprot id: E6SKZ5
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

644966:TMAR RS12235
gene id: 644966:TMAR_RS12235
uniprot id: E6SLU7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

644966:TMAR RS09995
gene id: 644966:TMAR_RS09995
uniprot id: E6SJ70
names: Similarity
messages: Belongs to the Nudix hydrolase family.

644966:TMAR RS11295
gene id: 644966:TMAR_RS11295
uniprot id: E6SKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

644966:TMAR RS11540
gene id: 644966:TMAR_RS11540
uniprot id: E6SLE2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

644966:TMAR RS10575
gene id: 644966:TMAR_RS10575
uniprot id: E6SJX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS05180
gene id: 644966:TMAR_RS05180
uniprot id: E6SJR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

644966:TMAR RS02605
gene id: 644966:TMAR_RS02605
uniprot id: E6SGZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

644966:TMAR RS04580
gene id: 644966:TMAR_RS04580
uniprot id: E6SJ11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

644966:TMAR RS11415
gene id: 644966:TMAR_RS11415
uniprot id: E6SKY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

644966:TMAR RS11185
gene id: 644966:TMAR_RS11185
uniprot id: E6SKU2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

644966:TMAR RS01765
gene id: 644966:TMAR_RS01765
uniprot id: E6SMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

644966:TMAR RS11730
gene id: 644966:TMAR_RS11730
uniprot id: E6SLH5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

644966:TMAR RS12200
gene id: 644966:TMAR_RS12200
uniprot id: E6SK37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

644966:TMAR RS05050
gene id: 644966:TMAR_RS05050
uniprot id: E6SJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

644966:TMAR RS04350
gene id: 644966:TMAR_RS04350
uniprot id: E6SIW7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

644966:TMAR RS03825
gene id: 644966:TMAR_RS03825
uniprot id: E6SI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS11330
gene id: 644966:TMAR_RS11330
uniprot id: E6SKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

644966:TMAR RS02935
gene id: 644966:TMAR_RS02935
uniprot id: E6SHC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

644966:TMAR RS06425
gene id: 644966:TMAR_RS06425
uniprot id: E6SLS4
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

644966:TMAR RS12180
gene id: 644966:TMAR_RS12180
uniprot id: E6SJE1
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

644966:TMAR RS07165
gene id: 644966:TMAR_RS07165
uniprot id: E6SMM9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

644966:TMAR RS07190
gene id: 644966:TMAR_RS07190
uniprot id: E6SMN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

644966:TMAR RS04990
gene id: 644966:TMAR_RS04990
uniprot id: E6SJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

644966:TMAR RS11375
gene id: 644966:TMAR_RS11375
uniprot id: E6SKX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

644966:TMAR RS10080
gene id: 644966:TMAR_RS10080
uniprot id: E6SJF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS08645
gene id: 644966:TMAR_RS08645
uniprot id: E6SHM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS09430
gene id: 644966:TMAR_RS09430
uniprot id: E6SIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05085
gene id: 644966:TMAR_RS05085
uniprot id: E6SJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

644966:TMAR RS03945
gene id: 644966:TMAR_RS03945
uniprot id: E6SII0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS06070
gene id: 644966:TMAR_RS06070
uniprot id: E6SL73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

644966:TMAR RS05910
gene id: 644966:TMAR_RS05910
uniprot id: E6SKR4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

644966:TMAR RS06595
gene id: 644966:TMAR_RS06595
uniprot id: E6SLV8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS10895
gene id: 644966:TMAR_RS10895
uniprot id: E6SKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

644966:TMAR RS01960
gene id: 644966:TMAR_RS01960
uniprot id: E6SG80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

644966:TMAR RS11725
gene id: 644966:TMAR_RS11725
uniprot id: E6SLH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

644966:TMAR RS08460
gene id: 644966:TMAR_RS08460
uniprot id: E6SHI5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

644966:TMAR RS09605
gene id: 644966:TMAR_RS09605
uniprot id: E6SIR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS03415
gene id: 644966:TMAR_RS03415
uniprot id: E6SHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS08545
gene id: 644966:TMAR_RS08545
uniprot id: E6SHK5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

644966:TMAR RS09515
gene id: 644966:TMAR_RS09515
uniprot id: E6SIQ2
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS06385
gene id: 644966:TMAR_RS06385
uniprot id: E6SLR6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

644966:TMAR RS00655
gene id: 644966:TMAR_RS00655
uniprot id: E6SL40
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

644966:TMAR RS11115
gene id: 644966:TMAR_RS11115
uniprot id: E6SKT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

644966:TMAR RS08330
gene id: 644966:TMAR_RS08330
uniprot id: E6SH90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

644966:TMAR RS08535
gene id: 644966:TMAR_RS08535
uniprot id: E6SHK3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

644966:TMAR RS04510
gene id: 644966:TMAR_RS04510
uniprot id: E6SIZ7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

644966:TMAR RS03495
gene id: 644966:TMAR_RS03495
uniprot id: E6SHV1
names: Similarity
messages: Belongs to the peptidase S33 family.

644966:TMAR RS06215
gene id: 644966:TMAR_RS06215
uniprot id: E6SLA2
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS11795
gene id: 644966:TMAR_RS11795
uniprot id: E6SLI6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

644966:TMAR RS11810
gene id: 644966:TMAR_RS11810
uniprot id: E6SLI9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

644966:TMAR RS08170
gene id: 644966:TMAR_RS08170
uniprot id: E6SH58
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

644966:TMAR RS04440
gene id: 644966:TMAR_RS04440
uniprot id: E6SIY4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS02845
gene id: 644966:TMAR_RS02845
uniprot id: E6SHA8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

644966:TMAR RS10685
gene id: 644966:TMAR_RS10685
uniprot id: E6SJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS14600
gene id: 644966:TMAR_RS14600
uniprot id: E6SHF0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

644966:TMAR RS09200
gene id: 644966:TMAR_RS09200
uniprot id: E6SIC1
names: Similarity
messages: Belongs to the GerABKA family.

644966:TMAR RS14525
gene id: 644966:TMAR_RS14525
uniprot id: E6SLH1
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS07220
gene id: 644966:TMAR_RS07220
uniprot id: E6SMP0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

644966:TMAR RS04145
gene id: 644966:TMAR_RS04145
uniprot id: E6SIM0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS08540
gene id: 644966:TMAR_RS08540
uniprot id: E6SHK4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

644966:TMAR RS06585
gene id: 644966:TMAR_RS06585
uniprot id: E6SLV6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

644966:TMAR RS06160
gene id: 644966:TMAR_RS06160
uniprot id: E6SL91
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS02115
gene id: 644966:TMAR_RS02115
uniprot id: E6SGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

644966:TMAR RS06455
gene id: 644966:TMAR_RS06455
uniprot id: E6SLT0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

644966:TMAR RS11390
gene id: 644966:TMAR_RS11390
uniprot id: E6SKY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

644966:TMAR RS00795
gene id: 644966:TMAR_RS00795
uniprot id: E6SLJ8
names: Similarity
messages: Belongs to the peptidase S58 family.

644966:TMAR RS02830
gene id: 644966:TMAR_RS02830
uniprot id: E6SHA5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

644966:TMAR RS02375
gene id: 644966:TMAR_RS02375
uniprot id: E6SGM9
names: Similarity
messages: Belongs to the glutamine synthetase family.

644966:TMAR RS05080
gene id: 644966:TMAR_RS05080
uniprot id: E6SJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

644966:TMAR RS11910
gene id: 644966:TMAR_RS11910
uniprot id: E6SLZ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

644966:TMAR RS11435
gene id: 644966:TMAR_RS11435
uniprot id: E6SKZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

644966:TMAR RS01160
gene id: 644966:TMAR_RS01160
uniprot id: E6SM04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

644966:TMAR RS05095
gene id: 644966:TMAR_RS05095
uniprot id: E6SJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

644966:TMAR RS04925
gene id: 644966:TMAR_RS04925
uniprot id: E6SJE7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

644966:TMAR RS01920
gene id: 644966:TMAR_RS01920
uniprot id: E6SG72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS03730
gene id: 644966:TMAR_RS03730
uniprot id: E6SI65
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

644966:TMAR RS01890
gene id: 644966:TMAR_RS01890
uniprot id: E6SG64
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

644966:TMAR RS11045
gene id: 644966:TMAR_RS11045
uniprot id: E6SKD8
names: Similarity
messages: Belongs to the MreC family.

644966:TMAR RS11200
gene id: 644966:TMAR_RS11200
uniprot id: E6SKU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

644966:TMAR RS04910
gene id: 644966:TMAR_RS04910
uniprot id: E6SJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

644966:TMAR RS08225
gene id: 644966:TMAR_RS08225
uniprot id: E6SH70
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS14055
gene id: 644966:TMAR_RS14055
uniprot id: E6SHC5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

644966:TMAR RS06990
gene id: 644966:TMAR_RS06990
uniprot id: E6SMC7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

644966:TMAR RS04050
gene id: 644966:TMAR_RS04050
uniprot id: E6SIK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

644966:TMAR RS10700
gene id: 644966:TMAR_RS10700
uniprot id: E6SJZ6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS05025
gene id: 644966:TMAR_RS05025
uniprot id: E6SJN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS08570
gene id: 644966:TMAR_RS08570
uniprot id: E6SHL0
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS02135
gene id: 644966:TMAR_RS02135
uniprot id: E6SGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

644966:TMAR RS11345
gene id: 644966:TMAR_RS11345
uniprot id: E6SKX3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

644966:TMAR RS09365
gene id: 644966:TMAR_RS09365
uniprot id: E6SIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

644966:TMAR RS00460
gene id: 644966:TMAR_RS00460
uniprot id: E6SL01
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

644966:TMAR RS07085
gene id: 644966:TMAR_RS07085
uniprot id: E6SML3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

644966:TMAR RS09800
gene id: 644966:TMAR_RS09800
uniprot id: E6SJ30
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

644966:TMAR RS02050
gene id: 644966:TMAR_RS02050
uniprot id: E6SG97
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

644966:TMAR RS11170
gene id: 644966:TMAR_RS11170
uniprot id: E6SKT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

644966:TMAR RS00620
gene id: 644966:TMAR_RS00620
uniprot id: E6SL34
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

644966:TMAR RS14210
gene id: 644966:TMAR_RS14210
uniprot id: E6SKS8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

644966:TMAR RS08240
gene id: 644966:TMAR_RS08240
uniprot id: E6SH73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

644966:TMAR RS04950
gene id: 644966:TMAR_RS04950
uniprot id: E6SJL7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

644966:TMAR RS04075
gene id: 644966:TMAR_RS04075
uniprot id: E6SIK6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS09205
gene id: 644966:TMAR_RS09205
uniprot id: E6SIC2
names: Similarity
messages: Belongs to the universal stress protein A family.

644966:TMAR RS00715
gene id: 644966:TMAR_RS00715
uniprot id: E6SL48
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

644966:TMAR RS04315
gene id: 644966:TMAR_RS04315
uniprot id: E6SIW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

644966:TMAR RS08260
gene id: 644966:TMAR_RS08260
uniprot id: E6SH76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

644966:TMAR RS04520
gene id: 644966:TMAR_RS04520
uniprot id: E6SIZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

644966:TMAR RS11030
gene id: 644966:TMAR_RS11030
uniprot id: E6SKD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

644966:TMAR RS04100
gene id: 644966:TMAR_RS04100
uniprot id: E6SIL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

644966:TMAR RS11845
gene id: 644966:TMAR_RS11845
uniprot id: E6SLY0
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS01000
gene id: 644966:TMAR_RS01000
uniprot id: E6SLN4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

644966:TMAR RS05710
gene id: 644966:TMAR_RS05710
uniprot id: E6SKM4
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

644966:TMAR RS08500
gene id: 644966:TMAR_RS08500
uniprot id: E6SHJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644966:TMAR RS10125
gene id: 644966:TMAR_RS10125
uniprot id: E6SJG4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS09960
gene id: 644966:TMAR_RS09960
uniprot id: E6SJ62
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

644966:TMAR RS00975
gene id: 644966:TMAR_RS00975
uniprot id: E6SLM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS11465
gene id: 644966:TMAR_RS11465
uniprot id: E6SLC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

644966:TMAR RS00935
gene id: 644966:TMAR_RS00935
uniprot id: E6SLM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

644966:TMAR RS00010
gene id: 644966:TMAR_RS00010
uniprot id: E6SK03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

644966:TMAR RS09240
gene id: 644966:TMAR_RS09240
uniprot id: E6SID0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

644966:TMAR RS09290
gene id: 644966:TMAR_RS09290
uniprot id: E6SIE1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

644966:TMAR RS08085
gene id: 644966:TMAR_RS08085
uniprot id: E6SH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

644966:TMAR RS01675
gene id: 644966:TMAR_RS01675
uniprot id: E6SMH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

644966:TMAR RS05725
gene id: 644966:TMAR_RS05725
uniprot id: E6SKM7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

644966:TMAR RS03190
gene id: 644966:TMAR_RS03190
uniprot id: E6SHP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS04045
gene id: 644966:TMAR_RS04045
uniprot id: E6SIK0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

644966:TMAR RS10580
gene id: 644966:TMAR_RS10580
uniprot id: E6SJX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

644966:TMAR RS08380
gene id: 644966:TMAR_RS08380
uniprot id: E6SHA0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

644966:TMAR RS00550
gene id: 644966:TMAR_RS00550
uniprot id: E6SL20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

644966:TMAR RS04355
gene id: 644966:TMAR_RS04355
uniprot id: E6SIW8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

644966:TMAR RS10100
gene id: 644966:TMAR_RS10100
uniprot id: E6SJF9
names: Subcellular Location Annotation
messages: Cytoplasm

644966:TMAR RS05055
gene id: 644966:TMAR_RS05055
uniprot id: E6SJN8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

644966:TMAR RS05590
gene id: 644966:TMAR_RS05590
uniprot id: E6SK68
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS12250
gene id: 644966:TMAR_RS12250
uniprot id: E6SMN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

644966:TMAR RS11750
gene id: 644966:TMAR_RS11750
uniprot id: E6SLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

644966:TMAR RS10985
gene id: 644966:TMAR_RS10985
uniprot id: E6SKC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

644966:TMAR RS00035
gene id: 644966:TMAR_RS00035
uniprot id: E6SKE5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

644966:TMAR RS03805
gene id: 644966:TMAR_RS03805
uniprot id: E6SI80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS10555
gene id: 644966:TMAR_RS10555
uniprot id: E6SJW8
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS03250
gene id: 644966:TMAR_RS03250
uniprot id: E6SHQ5
names: Similarity
messages: Belongs to the glutamate synthase family.

644966:TMAR RS10245
gene id: 644966:TMAR_RS10245
uniprot id: E6SJI9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

644966:TMAR RS03465
gene id: 644966:TMAR_RS03465
uniprot id: E6SHU5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

644966:TMAR RS02960
gene id: 644966:TMAR_RS02960
uniprot id: E6SHD1
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS11565
gene id: 644966:TMAR_RS11565
uniprot id: E6SLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

644966:TMAR RS06330
gene id: 644966:TMAR_RS06330
uniprot id: E6SLC5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

644966:TMAR RS11440
gene id: 644966:TMAR_RS11440
uniprot id: E6SKZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

644966:TMAR RS03960
gene id: 644966:TMAR_RS03960
uniprot id: E6SII3
names: Similarity
messages: Belongs to the glutamate synthase family.

644966:TMAR RS05995
gene id: 644966:TMAR_RS05995
uniprot id: E6SL58
names: Similarity
messages: Belongs to the asp23 family.

644966:TMAR RS05535
gene id: 644966:TMAR_RS05535
uniprot id: E6SK57
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

644966:TMAR RS09510
gene id: 644966:TMAR_RS09510
uniprot id: E6SIQ1
names: Similarity
messages: Belongs to the glutamine synthetase family.

644966:TMAR RS02325
gene id: 644966:TMAR_RS02325
uniprot id: E6SGL9
names: Similarity
messages: Belongs to the PGI/PMI family.

644966:TMAR RS10600
gene id: 644966:TMAR_RS10600
uniprot id: E6SJX6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

644966:TMAR RS02555
gene id: 644966:TMAR_RS02555
uniprot id: E6SGY0
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

644966:TMAR RS02395
gene id: 644966:TMAR_RS02395
uniprot id: E6SGN3
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS05645
gene id: 644966:TMAR_RS05645
uniprot id: E6SKL1
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

644966:TMAR RS06405
gene id: 644966:TMAR_RS06405
uniprot id: E6SLS0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

644966:TMAR RS06450
gene id: 644966:TMAR_RS06450
uniprot id: E6SLS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

644966:TMAR RS04870
gene id: 644966:TMAR_RS04870
uniprot id: E6SJD6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

644966:TMAR RS07325
gene id: 644966:TMAR_RS07325
uniprot id: E6SMR1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

644966:TMAR RS01080
gene id: 644966:TMAR_RS01080
uniprot id: E6SLQ0
names: Similarity
messages: Belongs to the FlgM family.

644966:TMAR RS04305
gene id: 644966:TMAR_RS04305
uniprot id: E6SIV8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

644966:TMAR RS11475
gene id: 644966:TMAR_RS11475
uniprot id: E6SLD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

644966:TMAR RS07345
gene id: 644966:TMAR_RS07345
uniprot id: E6SMR5
names: Subcellular Location Annotation
messages: Cell membrane

644966:TMAR RS02950
gene id: 644966:TMAR_RS02950
uniprot id: E6SHC9
names: Similarity
messages: Belongs to the asparagine synthetase family.

644966:TMAR RS09230
gene id: 644966:TMAR_RS09230
uniprot id: E6SIC7
names: Similarity
messages: Belongs to the peptidase C56 family.

644966:TMAR RS14700
gene id: 644966:TMAR_RS14700
uniprot id: E6SLV9
names: Similarity
messages: Belongs to the GerABKA family.

644966:TMAR RS10760
gene id: 644966:TMAR_RS10760
uniprot id: E6SK82
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

644966:TMAR RS06155
gene id: 644966:TMAR_RS06155
uniprot id: E6SL90
names: Similarity
messages: Belongs to the GSP E family.

644966:TMAR RS10595
gene id: 644966:TMAR_RS10595
uniprot id: E6SJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

644966:TMAR RS05675
gene id: 644966:TMAR_RS05675
uniprot id: E6SKL7
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

644966:TMAR RS01425
gene id: 644966:TMAR_RS01425
uniprot id: E6SM56
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

644966:TMAR RS03865
gene id: 644966:TMAR_RS03865
uniprot id: E6SI92
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

644966:TMAR RS03005
gene id: 644966:TMAR_RS03005
uniprot id: E6SHE0
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS11515
gene id: 644966:TMAR_RS11515
uniprot id: E6SLD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

644966:TMAR RS11430
gene id: 644966:TMAR_RS11430
uniprot id: E6SKZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

644966:TMAR RS08350
gene id: 644966:TMAR_RS08350
uniprot id: E6SH94
names: Similarity
messages: Belongs to the PstS family.

644966:TMAR RS09590
gene id: 644966:TMAR_RS09590
uniprot id: E6SIR6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

644966:TMAR RS11335
gene id: 644966:TMAR_RS11335
uniprot id: E6SKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05815
gene id: 644966:TMAR_RS05815
uniprot id: E6SKP5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

644966:TMAR RS01010
gene id: 644966:TMAR_RS01010
uniprot id: E6SLN6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

644966:TMAR RS10340
gene id: 644966:TMAR_RS10340
uniprot id: E6SJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

644966:TMAR RS07450
gene id: 644966:TMAR_RS07450
uniprot id: E6SGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

644966:TMAR RS14320
gene id: 644966:TMAR_RS14320
uniprot id: E6SMP8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

644966:TMAR RS10865
gene id: 644966:TMAR_RS10865
uniprot id: E6SKA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

644966:TMAR RS05485
gene id: 644966:TMAR_RS05485
uniprot id: E6SK47
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

644966:TMAR RS05975
gene id: 644966:TMAR_RS05975
uniprot id: E6SKS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

644966:TMAR RS04590
gene id: 644966:TMAR_RS04590
uniprot id: E6SJ80
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

644966:TMAR RS01665
gene id: 644966:TMAR_RS01665
uniprot id: E6SMH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

644966:TMAR RS02530
gene id: 644966:TMAR_RS02530
uniprot id: E6SGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05395
gene id: 644966:TMAR_RS05395
uniprot id: E6SK29
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

644966:TMAR RS08990
gene id: 644966:TMAR_RS08990
uniprot id: E6SI12
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS10765
gene id: 644966:TMAR_RS10765
uniprot id: E6SK84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

644966:TMAR RS06310
gene id: 644966:TMAR_RS06310
uniprot id: E6SLC1
names: Similarity
messages: Belongs to the thioredoxin family.

644966:TMAR RS05680
gene id: 644966:TMAR_RS05680
uniprot id: E6SKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

644966:TMAR RS09940
gene id: 644966:TMAR_RS09940
uniprot id: E6SJ58
names: Similarity
messages: Belongs to the citrate synthase family.

644966:TMAR RS10755
gene id: 644966:TMAR_RS10755
uniprot id: E6SK81
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

644966:TMAR RS01685
gene id: 644966:TMAR_RS01685
uniprot id: E6SMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

644966:TMAR RS05940
gene id: 644966:TMAR_RS05940
uniprot id: E6SKS0
names: Similarity
messages: Belongs to the DapA family.

644966:TMAR RS07250
gene id: 644966:TMAR_RS07250
uniprot id: E6SMP6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

644966:TMAR RS01185
gene id: 644966:TMAR_RS01185
uniprot id: E6SM09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS11740
gene id: 644966:TMAR_RS11740
uniprot id: E6SLH7
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

644966:TMAR RS05945
gene id: 644966:TMAR_RS05945
uniprot id: E6SKS1
names: Similarity
messages: Belongs to the TlyA family.

644966:TMAR RS10145
gene id: 644966:TMAR_RS10145
uniprot id: E6SJG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS06610
gene id: 644966:TMAR_RS06610
uniprot id: E6SLW1
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

644966:TMAR RS11035
gene id: 644966:TMAR_RS11035
uniprot id: E6SKD6
names: Similarity
messages: Belongs to the transpeptidase family.

644966:TMAR RS06430
gene id: 644966:TMAR_RS06430
uniprot id: E6SLS5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

644966:TMAR RS05570
gene id: 644966:TMAR_RS05570
uniprot id: E6SK64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

644966:TMAR RS12325
gene id: 644966:TMAR_RS12325
uniprot id: E6SH68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.
messages: Monomer.

644966:TMAR RS07530
gene id: 644966:TMAR_RS07530
uniprot id: E6SGE3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

644966:TMAR RS04665
gene id: 644966:TMAR_RS04665
uniprot id: E6SJ96
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

644966:TMAR RS03110
gene id: 644966:TMAR_RS03110
uniprot id: E6SHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

644966:TMAR RS03060
gene id: 644966:TMAR_RS03060
uniprot id: E6SHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

644966:TMAR RS06210
gene id: 644966:TMAR_RS06210
uniprot id: E6SLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0473 family.
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

644966:TMAR RS11340
gene id: 644966:TMAR_RS11340
uniprot id: E6SKX2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

644966:TMAR RS09195
gene id: 644966:TMAR_RS09195
uniprot id: E6SIC0
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

644966:TMAR RS00760
gene id: 644966:TMAR_RS00760
uniprot id: E6SLJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS06260
gene id: 644966:TMAR_RS06260
uniprot id: E6SLB1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

644966:TMAR RS02985
gene id: 644966:TMAR_RS02985
uniprot id: E6SHD6
names: Similarity
messages: Belongs to the EamA transporter family.

644966:TMAR RS11090
gene id: 644966:TMAR_RS11090
uniprot id: E6SKT1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

644966:TMAR RS10850
gene id: 644966:TMAR_RS10850
uniprot id: E6SKA1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

644966:TMAR RS09270
gene id: 644966:TMAR_RS09270
uniprot id: E6SID7
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS04845
gene id: 644966:TMAR_RS04845
uniprot id: E6SJD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

644966:TMAR RS05035
gene id: 644966:TMAR_RS05035
uniprot id: E6SJN4
names: Similarity
messages: Belongs to the FlgD family.

644966:TMAR RS03330
gene id: 644966:TMAR_RS03330
uniprot id: E6SHS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644966:TMAR RS03605
gene id: 644966:TMAR_RS03605
uniprot id: E6SI41
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

644966:TMAR RS05270
gene id: 644966:TMAR_RS05270
uniprot id: E6SJT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

644966:TMAR RS06770
gene id: 644966:TMAR_RS06770
uniprot id: E6SM83
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

644966:TMAR RS01045
gene id: 644966:TMAR_RS01045
uniprot id: E6SLP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

644966:TMAR RS06620
gene id: 644966:TMAR_RS06620
uniprot id: E6SLW3
names: Similarity
messages: Belongs to the citrate synthase family.

644966:TMAR RS01350
gene id: 644966:TMAR_RS01350
uniprot id: E6SM41
names: Similarity
messages: Belongs to the peptidase M29 family.

644966:TMAR RS09000
gene id: 644966:TMAR_RS09000
uniprot id: E6SI14
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

644966:TMAR RS00555
gene id: 644966:TMAR_RS00555
uniprot id: E6SL21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

644966:TMAR RS11350
gene id: 644966:TMAR_RS11350
uniprot id: E6SKX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

644966:TMAR RS06880
gene id: 644966:TMAR_RS06880
uniprot id: E6SMA5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

644966:TMAR RS05040
gene id: 644966:TMAR_RS05040
uniprot id: E6SJN5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

644966:TMAR RS03410
gene id: 644966:TMAR_RS03410
uniprot id: E6SHT4
names: Similarity
messages: Belongs to the GSP E family.

644966:TMAR RS07385
gene id: 644966:TMAR_RS07385
uniprot id: E6SGB4
names: Similarity
messages: Belongs to the TrpC family.

644966:TMAR RS05175
gene id: 644966:TMAR_RS05175
uniprot id: E6SJR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

644966:TMAR RS09805
gene id: 644966:TMAR_RS09805
uniprot id: E6SJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS11525
gene id: 644966:TMAR_RS11525
uniprot id: E6SLD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

644966:TMAR RS01315
gene id: 644966:TMAR_RS01315
uniprot id: E6SM34
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

644966:TMAR RS03360
gene id: 644966:TMAR_RS03360
uniprot id: E6SHS5
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS03230
gene id: 644966:TMAR_RS03230
uniprot id: E6SHQ1
names: Similarity
messages: Belongs to the asparagine synthetase family.

644966:TMAR RS01940
gene id: 644966:TMAR_RS01940
uniprot id: E6SG76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

644966:TMAR RS01330
gene id: 644966:TMAR_RS01330
uniprot id: E6SM37
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

644966:TMAR RS01310
gene id: 644966:TMAR_RS01310
uniprot id: E6SM33
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

644966:TMAR RS04915
gene id: 644966:TMAR_RS04915
uniprot id: E6SJE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

644966:TMAR RS06955
gene id: 644966:TMAR_RS06955
uniprot id: E6SMC0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

644966:TMAR RS06280
gene id: 644966:TMAR_RS06280
uniprot id: E6SLB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

644966:TMAR RS01155
gene id: 644966:TMAR_RS01155
uniprot id: E6SM03
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

644966:TMAR RS11620
gene id: 644966:TMAR_RS11620
uniprot id: E6SLF3
names: Similarity
messages: Belongs to the ycf81 family.

644966:TMAR RS11410
gene id: 644966:TMAR_RS11410
uniprot id: E6SKY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

644966:TMAR RS11805
gene id: 644966:TMAR_RS11805
uniprot id: E6SLI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

644966:TMAR RS04595
gene id: 644966:TMAR_RS04595
uniprot id: E6SJ81
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

644966:TMAR RS10975
gene id: 644966:TMAR_RS10975
uniprot id: E6SKC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

644966:TMAR RS02205
gene id: 644966:TMAR_RS02205
uniprot id: E6SGJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

644966:TMAR RS03575
gene id: 644966:TMAR_RS03575
uniprot id: E6SI36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

644966:TMAR RS01195
gene id: 644966:TMAR_RS01195
uniprot id: E6SM11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

644966:TMAR RS01660
gene id: 644966:TMAR_RS01660
uniprot id: E6SMH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

644966:TMAR RS09880
gene id: 644966:TMAR_RS09880
uniprot id: E6SJ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS11495
gene id: 644966:TMAR_RS11495
uniprot id: E6SLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

644966:TMAR RS01300
gene id: 644966:TMAR_RS01300
uniprot id: E6SM31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

644966:TMAR RS07540
gene id: 644966:TMAR_RS07540
uniprot id: E6SGE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS07240
gene id: 644966:TMAR_RS07240
uniprot id: E6SMP4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

644966:TMAR RS11785
gene id: 644966:TMAR_RS11785
uniprot id: E6SLI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

644966:TMAR RS10495
gene id: 644966:TMAR_RS10495
uniprot id: E6SJV8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

644966:TMAR RS07705
gene id: 644966:TMAR_RS07705
uniprot id: E6SGH4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644966:TMAR RS03085
gene id: 644966:TMAR_RS03085
uniprot id: E6SHF6
names: Similarity
messages: Belongs to the EamA transporter family.

644966:TMAR RS11885
gene id: 644966:TMAR_RS11885
uniprot id: E6SLY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

644966:TMAR RS01090
gene id: 644966:TMAR_RS01090
uniprot id: E6SLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

644966:TMAR RS03915
gene id: 644966:TMAR_RS03915
uniprot id: E6SIH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

644966:TMAR RS04900
gene id: 644966:TMAR_RS04900
uniprot id: E6SJE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

644966:TMAR RS02420
gene id: 644966:TMAR_RS02420
uniprot id: E6SGN8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

644966:TMAR RS11395
gene id: 644966:TMAR_RS11395
uniprot id: E6SKY3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

644966:TMAR RS03935
gene id: 644966:TMAR_RS03935
uniprot id: E6SIH8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

644966:TMAR RS03270
gene id: 644966:TMAR_RS03270
uniprot id: E6SHQ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS00955
gene id: 644966:TMAR_RS00955
uniprot id: E6SLM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

644966:TMAR RS05595
gene id: 644966:TMAR_RS05595
uniprot id: E6SK69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

644966:TMAR RS02680
gene id: 644966:TMAR_RS02680
uniprot id: E6SH07
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

644966:TMAR RS04465
gene id: 644966:TMAR_RS04465
uniprot id: E6SIY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

644966:TMAR RS05235
gene id: 644966:TMAR_RS05235
uniprot id: E6SJS4
names: Similarity
messages: Belongs to the ribF family.

644966:TMAR RS04600
gene id: 644966:TMAR_RS04600
uniprot id: E6SJ82
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

644966:TMAR RS01005
gene id: 644966:TMAR_RS01005
uniprot id: E6SLN5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

644966:TMAR RS10615
gene id: 644966:TMAR_RS10615
uniprot id: E6SJX9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

644966:TMAR RS00945
gene id: 644966:TMAR_RS00945
uniprot id: E6SLM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

644966:TMAR RS00660
gene id: 644966:TMAR_RS00660
uniprot id: E6SL41
names: Similarity
messages: Belongs to the cytochrome b560 family.

644966:TMAR RS04330
gene id: 644966:TMAR_RS04330
uniprot id: E6SIW3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

644966:TMAR RS08620
gene id: 644966:TMAR_RS08620
uniprot id: E6SHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS00995
gene id: 644966:TMAR_RS00995
uniprot id: E6SLN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS11380
gene id: 644966:TMAR_RS11380
uniprot id: E6SKY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

644966:TMAR RS07820
gene id: 644966:TMAR_RS07820
uniprot id: E6SGR7
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS06980
gene id: 644966:TMAR_RS06980
uniprot id: E6SMC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

644966:TMAR RS06895
gene id: 644966:TMAR_RS06895
uniprot id: E6SMA8
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

644966:TMAR RS10870
gene id: 644966:TMAR_RS10870
uniprot id: E6SKA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

644966:TMAR RS08690
gene id: 644966:TMAR_RS08690
uniprot id: E6SHN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644966:TMAR RS13925
gene id: 644966:TMAR_RS13925
uniprot id: E6SLF1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

644966:TMAR RS05430
gene id: 644966:TMAR_RS05430
uniprot id: E6SK36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS10040
gene id: 644966:TMAR_RS10040
uniprot id: E6SJ78
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Homodimer.

644966:TMAR RS02400
gene id: 644966:TMAR_RS02400
uniprot id: E6SGN4
names: Similarity
messages: Belongs to the AHA1 family.

644966:TMAR RS06680
gene id: 644966:TMAR_RS06680
uniprot id: E6SLX5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

644966:TMAR RS04790
gene id: 644966:TMAR_RS04790
uniprot id: E6SJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

644966:TMAR RS04015
gene id: 644966:TMAR_RS04015
uniprot id: E6SIJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

644966:TMAR RS10745
gene id: 644966:TMAR_RS10745
uniprot id: E6SK79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

644966:TMAR RS00475
gene id: 644966:TMAR_RS00475
uniprot id: E6SL04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

644966:TMAR RS11870
gene id: 644966:TMAR_RS11870
uniprot id: E6SLY5
names: Similarity
messages: Belongs to the ParB family.

644966:TMAR RS06810
gene id: 644966:TMAR_RS06810
uniprot id: E6SM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS06185
gene id: 644966:TMAR_RS06185
uniprot id: E6SL96
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS04680
gene id: 644966:TMAR_RS04680
uniprot id: E6SJ99
names: Similarity
messages: Belongs to the RemA family.

644966:TMAR RS05145
gene id: 644966:TMAR_RS05145
uniprot id: E6SJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

644966:TMAR RS06465
gene id: 644966:TMAR_RS06465
uniprot id: E6SLT2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

644966:TMAR RS04930
gene id: 644966:TMAR_RS04930
uniprot id: E6SJE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS04690
gene id: 644966:TMAR_RS04690
uniprot id: E6SJA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

644966:TMAR RS02590
gene id: 644966:TMAR_RS02590
uniprot id: E6SGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS07070
gene id: 644966:TMAR_RS07070
uniprot id: E6SML0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS10095
gene id: 644966:TMAR_RS10095
uniprot id: E6SJF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

644966:TMAR RS02785
gene id: 644966:TMAR_RS02785
uniprot id: E6SH29
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS03070
gene id: 644966:TMAR_RS03070
uniprot id: E6SHF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

644966:TMAR RS02775
gene id: 644966:TMAR_RS02775
uniprot id: E6SH27
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

644966:TMAR RS11205
gene id: 644966:TMAR_RS11205
uniprot id: E6SKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

644966:TMAR RS13520
gene id: 644966:TMAR_RS13520
uniprot id: E6SLJ6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Belongs to the DHPS family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

644966:TMAR RS01165
gene id: 644966:TMAR_RS01165
uniprot id: E6SM05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

644966:TMAR RS06570
gene id: 644966:TMAR_RS06570
uniprot id: E6SLV3
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

644966:TMAR RS01865
gene id: 644966:TMAR_RS01865
uniprot id: E6SG59
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

644966:TMAR RS11210
gene id: 644966:TMAR_RS11210
uniprot id: E6SKU7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

644966:TMAR RS00725
gene id: 644966:TMAR_RS00725
uniprot id: E6SL50
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

644966:TMAR RS08480
gene id: 644966:TMAR_RS08480
uniprot id: E6SHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

644966:TMAR RS01205
gene id: 644966:TMAR_RS01205
uniprot id: E6SM13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

644966:TMAR RS14805
gene id: 644966:TMAR_RS14805
uniprot id: E6SJX8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

644966:TMAR RS10425
gene id: 644966:TMAR_RS10425
uniprot id: E6SJU4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

644966:TMAR RS02305
gene id: 644966:TMAR_RS02305
uniprot id: E6SGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

644966:TMAR RS02880
gene id: 644966:TMAR_RS02880
uniprot id: E6SHB5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

644966:TMAR RS04995
gene id: 644966:TMAR_RS04995
uniprot id: E6SJM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

644966:TMAR RS02735
gene id: 644966:TMAR_RS02735
uniprot id: E6SH19
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS00915
gene id: 644966:TMAR_RS00915
uniprot id: E6SLL7
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS02315
gene id: 644966:TMAR_RS02315
uniprot id: E6SGL7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS00615
gene id: 644966:TMAR_RS00615
uniprot id: E6SL32
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS07415
gene id: 644966:TMAR_RS07415
uniprot id: E6SGC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

644966:TMAR RS09685
gene id: 644966:TMAR_RS09685
uniprot id: E6SIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS08900
gene id: 644966:TMAR_RS08900
uniprot id: E6SHZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS06905
gene id: 644966:TMAR_RS06905
uniprot id: E6SMB0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS14595
gene id: 644966:TMAR_RS14595
uniprot id: E6SH18
names: Similarity
messages: Belongs to the UPF0045 family.

644966:TMAR RS09850
gene id: 644966:TMAR_RS09850
uniprot id: E6SJ40
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS08385
gene id: 644966:TMAR_RS08385
uniprot id: E6SHA1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

644966:TMAR RS12290
gene id: 644966:TMAR_RS12290
uniprot id: E6SGR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

644966:TMAR RS00900
gene id: 644966:TMAR_RS00900
uniprot id: E6SLL4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

644966:TMAR RS05115
gene id: 644966:TMAR_RS05115
uniprot id: E6SJQ0
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

644966:TMAR RS05785
gene id: 644966:TMAR_RS05785
uniprot id: E6SKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS11905
gene id: 644966:TMAR_RS11905
uniprot id: E6SLZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

644966:TMAR RS08205
gene id: 644966:TMAR_RS08205
uniprot id: E6SH65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

644966:TMAR RS00970
gene id: 644966:TMAR_RS00970
uniprot id: E6SLM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

644966:TMAR RS10890
gene id: 644966:TMAR_RS10890
uniprot id: E6SKA9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

644966:TMAR RS11500
gene id: 644966:TMAR_RS11500
uniprot id: E6SLD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

644966:TMAR RS10110
gene id: 644966:TMAR_RS10110
uniprot id: E6SJG1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

644966:TMAR RS11815
gene id: 644966:TMAR_RS11815
uniprot id: E6SLJ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

644966:TMAR RS13795
gene id: 644966:TMAR_RS13795
uniprot id: E6SMJ2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

644966:TMAR RS11305
gene id: 644966:TMAR_RS11305
uniprot id: E6SKW5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

644966:TMAR RS09130
gene id: 644966:TMAR_RS09130
uniprot id: E6SIA9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644966:TMAR RS10880
gene id: 644966:TMAR_RS10880
uniprot id: E6SKA7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

644966:TMAR RS11175
gene id: 644966:TMAR_RS11175
uniprot id: E6SKU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

644966:TMAR RS04140
gene id: 644966:TMAR_RS04140
uniprot id: E6SIL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05250
gene id: 644966:TMAR_RS05250
uniprot id: E6SJS7
names: Similarity
messages: Belongs to the peptidase M16 family.

644966:TMAR RS06080
gene id: 644966:TMAR_RS06080
uniprot id: E6SL75
names: Similarity
messages: Belongs to the Nudix hydrolase family.

644966:TMAR RS01450
gene id: 644966:TMAR_RS01450
uniprot id: E6SM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

644966:TMAR RS00800
gene id: 644966:TMAR_RS00800
uniprot id: E6SLJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

644966:TMAR RS12160
gene id: 644966:TMAR_RS12160
uniprot id: E6SJA4
names: Cofactor
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

644966:TMAR RS01410
gene id: 644966:TMAR_RS01410
uniprot id: E6SM53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

644966:TMAR RS11355
gene id: 644966:TMAR_RS11355
uniprot id: E6SKX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

644966:TMAR RS02695
gene id: 644966:TMAR_RS02695
uniprot id: E6SH11
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS10995
gene id: 644966:TMAR_RS10995
uniprot id: E6SKC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

644966:TMAR RS04250
gene id: 644966:TMAR_RS04250
uniprot id: E6SIU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

644966:TMAR RS11560
gene id: 644966:TMAR_RS11560
uniprot id: E6SLE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

644966:TMAR RS01095
gene id: 644966:TMAR_RS01095
uniprot id: E6SLQ3
names: Similarity
messages: Belongs to the bacterial flagellin family.

644966:TMAR RS01805
gene id: 644966:TMAR_RS01805
uniprot id: E6SG49
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

644966:TMAR RS01750
gene id: 644966:TMAR_RS01750
uniprot id: E6SMJ3
names: Similarity
messages: Belongs to the EamA transporter family.

644966:TMAR RS08825
gene id: 644966:TMAR_RS08825
uniprot id: E6SHX9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

644966:TMAR RS04975
gene id: 644966:TMAR_RS04975
uniprot id: E6SJM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

644966:TMAR RS06440
gene id: 644966:TMAR_RS06440
uniprot id: E6SLS7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

644966:TMAR RS04860
gene id: 644966:TMAR_RS04860
uniprot id: E6SJD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

644966:TMAR RS02875
gene id: 644966:TMAR_RS02875
uniprot id: E6SHB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05240
gene id: 644966:TMAR_RS05240
uniprot id: E6SJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

644966:TMAR RS05515
gene id: 644966:TMAR_RS05515
uniprot id: E6SK53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

644966:TMAR RS03800
gene id: 644966:TMAR_RS03800
uniprot id: E6SI79
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS03580
gene id: 644966:TMAR_RS03580
uniprot id: E6SI37
names: Similarity
messages: Belongs to the peptidase S8 family.

644966:TMAR RS02610
gene id: 644966:TMAR_RS02610
uniprot id: E6SGZ3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

644966:TMAR RS00685
gene id: 644966:TMAR_RS00685
uniprot id: E6SL45
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

644966:TMAR RS05760
gene id: 644966:TMAR_RS05760
uniprot id: E6SKN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

644966:TMAR RS10925
gene id: 644966:TMAR_RS10925
uniprot id: E6SKB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

644966:TMAR RS10955
gene id: 644966:TMAR_RS10955
uniprot id: E6SKC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

644966:TMAR RS11645
gene id: 644966:TMAR_RS11645
uniprot id: E6SLF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

644966:TMAR RS09680
gene id: 644966:TMAR_RS09680
uniprot id: E6SIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS00885
gene id: 644966:TMAR_RS00885
uniprot id: E6SLL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

644966:TMAR RS05605
gene id: 644966:TMAR_RS05605
uniprot id: E6SK71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

644966:TMAR RS00720
gene id: 644966:TMAR_RS00720
uniprot id: E6SL49
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the C-terminal section; belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: In the N-terminal section; belongs to the MobA family.

644966:TMAR RS01610
gene id: 644966:TMAR_RS01610
uniprot id: E6SMG4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

644966:TMAR RS03405
gene id: 644966:TMAR_RS03405
uniprot id: E6SHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

644966:TMAR RS02210
gene id: 644966:TMAR_RS02210
uniprot id: E6SGJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

644966:TMAR RS11325
gene id: 644966:TMAR_RS11325
uniprot id: E6SKW9
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS12255
gene id: 644966:TMAR_RS12255
uniprot id: E6SMP2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

644966:TMAR RS11485
gene id: 644966:TMAR_RS11485
uniprot id: E6SLD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

644966:TMAR RS04855
gene id: 644966:TMAR_RS04855
uniprot id: E6SJD3
names: Similarity
messages: Belongs to the fabD family.

644966:TMAR RS05875
gene id: 644966:TMAR_RS05875
uniprot id: E6SKQ7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

644966:TMAR RS11755
gene id: 644966:TMAR_RS11755
uniprot id: E6SLI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

644966:TMAR RS06285
gene id: 644966:TMAR_RS06285
uniprot id: E6SLB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

644966:TMAR RS01320
gene id: 644966:TMAR_RS01320
uniprot id: E6SM35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

644966:TMAR RS06125
gene id: 644966:TMAR_RS06125
uniprot id: E6SL84
names: Similarity
messages: Belongs to the GSP E family.

644966:TMAR RS03875
gene id: 644966:TMAR_RS03875
uniprot id: E6SIG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS02110
gene id: 644966:TMAR_RS02110
uniprot id: E6SGA7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

644966:TMAR RS09845
gene id: 644966:TMAR_RS09845
uniprot id: E6SJ39
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

644966:TMAR RS10335
gene id: 644966:TMAR_RS10335
uniprot id: E6SJK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

644966:TMAR RS00965
gene id: 644966:TMAR_RS00965
uniprot id: E6SLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

644966:TMAR RS05185
gene id: 644966:TMAR_RS05185
uniprot id: E6SJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

644966:TMAR RS07915
gene id: 644966:TMAR_RS07915
uniprot id: E6SGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

644966:TMAR RS04865
gene id: 644966:TMAR_RS04865
uniprot id: E6SJD5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

644966:TMAR RS03710
gene id: 644966:TMAR_RS03710
uniprot id: E6SI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS05900
gene id: 644966:TMAR_RS05900
uniprot id: E6SKR2
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS07665
gene id: 644966:TMAR_RS07665
uniprot id: E6SGG6
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS14795
gene id: 644966:TMAR_RS14795
uniprot id: E6SJH1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS04460
gene id: 644966:TMAR_RS04460
uniprot id: E6SIY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS00540
gene id: 644966:TMAR_RS00540
uniprot id: E6SL18
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS05135
gene id: 644966:TMAR_RS05135
uniprot id: E6SJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

644966:TMAR RS05555
gene id: 644966:TMAR_RS05555
uniprot id: E6SK61
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644966:TMAR RS08735
gene id: 644966:TMAR_RS08735
uniprot id: E6SHV7
names: Similarity
messages: Belongs to the selenium-binding protein family.

644966:TMAR RS06615
gene id: 644966:TMAR_RS06615
uniprot id: E6SLW2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS04375
gene id: 644966:TMAR_RS04375
uniprot id: E6SIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

644966:TMAR RS01060
gene id: 644966:TMAR_RS01060
uniprot id: E6SLP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

644966:TMAR RS02490
gene id: 644966:TMAR_RS02490
uniprot id: E6SGW7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

644966:TMAR RS10715
gene id: 644966:TMAR_RS10715
uniprot id: E6SJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

644966:TMAR RS06890
gene id: 644966:TMAR_RS06890
uniprot id: E6SMA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

644966:TMAR RS05195
gene id: 644966:TMAR_RS05195
uniprot id: E6SJR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

644966:TMAR RS10770
gene id: 644966:TMAR_RS10770
uniprot id: E6SK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

644966:TMAR RS09425
gene id: 644966:TMAR_RS09425
uniprot id: E6SIN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS01435
gene id: 644966:TMAR_RS01435
uniprot id: E6SM58
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

644966:TMAR RS05705
gene id: 644966:TMAR_RS05705
uniprot id: E6SKM3
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

644966:TMAR RS00770
gene id: 644966:TMAR_RS00770
uniprot id: E6SLJ3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

644966:TMAR RS04450
gene id: 644966:TMAR_RS04450
uniprot id: E6SIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

644966:TMAR RS11420
gene id: 644966:TMAR_RS11420
uniprot id: E6SKY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

644966:TMAR RS05285
gene id: 644966:TMAR_RS05285
uniprot id: E6SJT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS04260
gene id: 644966:TMAR_RS04260
uniprot id: E6SIU9
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS00400
gene id: 644966:TMAR_RS00400
uniprot id: E6SKZ7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

644966:TMAR RS11460
gene id: 644966:TMAR_RS11460
uniprot id: E6SLC7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

644966:TMAR RS02640
gene id: 644966:TMAR_RS02640
uniprot id: E6SGZ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

644966:TMAR RS06960
gene id: 644966:TMAR_RS06960
uniprot id: E6SMC1
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

644966:TMAR RS04385
gene id: 644966:TMAR_RS04385
uniprot id: E6SIX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

644966:TMAR RS05105
gene id: 644966:TMAR_RS05105
uniprot id: E6SJP8
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

644966:TMAR RS10330
gene id: 644966:TMAR_RS10330
uniprot id: E6SJK4
names: Similarity
messages: Belongs to the ComB family.

644966:TMAR RS11250
gene id: 644966:TMAR_RS11250
uniprot id: E6SKV5
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS01515
gene id: 644966:TMAR_RS01515
uniprot id: E6SME4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

644966:TMAR RS10375
gene id: 644966:TMAR_RS10375
uniprot id: E6SJL3
names: Similarity
messages: Belongs to the archease family.

644966:TMAR RS13990
gene id: 644966:TMAR_RS13990
uniprot id: E6SM60
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

644966:TMAR RS04740
gene id: 644966:TMAR_RS04740
uniprot id: E6SJB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

644966:TMAR RS11425
gene id: 644966:TMAR_RS11425
uniprot id: E6SKY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

644966:TMAR RS06575
gene id: 644966:TMAR_RS06575
uniprot id: E6SLV4
names: Similarity
messages: Belongs to the SfsA family.

644966:TMAR RS07100
gene id: 644966:TMAR_RS07100
uniprot id: E6SML6
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS10250
gene id: 644966:TMAR_RS10250
uniprot id: E6SJJ0
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

644966:TMAR RS00580
gene id: 644966:TMAR_RS00580
uniprot id: E6SL26
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

644966:TMAR RS06420
gene id: 644966:TMAR_RS06420
uniprot id: E6SLS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

644966:TMAR RS02295
gene id: 644966:TMAR_RS02295
uniprot id: E6SGL3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS06805
gene id: 644966:TMAR_RS06805
uniprot id: E6SM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS03105
gene id: 644966:TMAR_RS03105
uniprot id: E6SHG0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

644966:TMAR RS07380
gene id: 644966:TMAR_RS07380
uniprot id: E6SGB3
names: Similarity
messages: Belongs to the TrpF family.

644966:TMAR RS03515
gene id: 644966:TMAR_RS03515
uniprot id: E6SI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS07320
gene id: 644966:TMAR_RS07320
uniprot id: E6SMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

644966:TMAR RS10875
gene id: 644966:TMAR_RS10875
uniprot id: E6SKA6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

644966:TMAR RS10835
gene id: 644966:TMAR_RS10835
uniprot id: E6SK98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

644966:TMAR RS11660
gene id: 644966:TMAR_RS11660
uniprot id: E6SLG1
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

644966:TMAR RS08210
gene id: 644966:TMAR_RS08210
uniprot id: E6SH67
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS01495
gene id: 644966:TMAR_RS01495
uniprot id: E6SME0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

644966:TMAR RS06325
gene id: 644966:TMAR_RS06325
uniprot id: E6SLC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

644966:TMAR RS11860
gene id: 644966:TMAR_RS11860
uniprot id: E6SLY3
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

644966:TMAR RS10190
gene id: 644966:TMAR_RS10190
uniprot id: E6SJH8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

644966:TMAR RS00870
gene id: 644966:TMAR_RS00870
uniprot id: E6SLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

644966:TMAR RS00565
gene id: 644966:TMAR_RS00565
uniprot id: E6SL23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

644966:TMAR RS00045
gene id: 644966:TMAR_RS00045
uniprot id: E6SKE7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS01705
gene id: 644966:TMAR_RS01705
uniprot id: E6SMI3
names: Similarity
messages: Belongs to the universal stress protein A family.

644966:TMAR RS05585
gene id: 644966:TMAR_RS05585
uniprot id: E6SK67
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

644966:TMAR RS07370
gene id: 644966:TMAR_RS07370
uniprot id: E6SMS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

644966:TMAR RS08780
gene id: 644966:TMAR_RS08780
uniprot id: E6SHW6
names: Similarity
messages: Belongs to the AHA1 family.

644966:TMAR RS06700
gene id: 644966:TMAR_RS06700
uniprot id: E6SM69
names: Similarity
messages: Belongs to the BMP lipoprotein family.

644966:TMAR RS08165
gene id: 644966:TMAR_RS08165
uniprot id: E6SH57
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

644966:TMAR RS02425
gene id: 644966:TMAR_RS02425
uniprot id: E6SGN9
names: Similarity
messages: Belongs to the FBPase class 2 family.

644966:TMAR RS09775
gene id: 644966:TMAR_RS09775
uniprot id: E6SJ24
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

644966:TMAR RS12270
gene id: 644966:TMAR_RS12270
uniprot id: E6SGB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

644966:TMAR RS10605
gene id: 644966:TMAR_RS10605
uniprot id: E6SJX7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

644966:TMAR RS11100
gene id: 644966:TMAR_RS11100
uniprot id: E6SKT3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

644966:TMAR RS08405
gene id: 644966:TMAR_RS08405
uniprot id: E6SHH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS01395
gene id: 644966:TMAR_RS01395
uniprot id: E6SM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS07310
gene id: 644966:TMAR_RS07310
uniprot id: E6SMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS04030
gene id: 644966:TMAR_RS04030
uniprot id: E6SIJ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

644966:TMAR RS11970
gene id: 644966:TMAR_RS11970
uniprot id: E6SL56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

644966:TMAR RS02170
gene id: 644966:TMAR_RS02170
uniprot id: E6SGJ0
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

644966:TMAR RS05855
gene id: 644966:TMAR_RS05855
uniprot id: E6SKQ3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

644966:TMAR RS05545
gene id: 644966:TMAR_RS05545
uniprot id: E6SK59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS04565
gene id: 644966:TMAR_RS04565
uniprot id: E6SJ08
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS01120
gene id: 644966:TMAR_RS01120
uniprot id: E6SLZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

644966:TMAR RS11025
gene id: 644966:TMAR_RS11025
uniprot id: E6SKD4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

644966:TMAR RS11505
gene id: 644966:TMAR_RS11505
uniprot id: E6SLD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

644966:TMAR RS07645
gene id: 644966:TMAR_RS07645
uniprot id: E6SGG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

644966:TMAR RS02710
gene id: 644966:TMAR_RS02710
uniprot id: E6SH14
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

644966:TMAR RS05335
gene id: 644966:TMAR_RS05335
uniprot id: E6SK17
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

644966:TMAR RS07630
gene id: 644966:TMAR_RS07630
uniprot id: E6SGF9
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS08895
gene id: 644966:TMAR_RS08895
uniprot id: E6SHZ3
names: Subunit
messages: Dimer of large and small chains.

644966:TMAR RS08105
gene id: 644966:TMAR_RS08105
uniprot id: E6SH44
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

644966:TMAR RS04215
gene id: 644966:TMAR_RS04215
uniprot id: E6SIM9
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS00645
gene id: 644966:TMAR_RS00645
uniprot id: E6SL38
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

644966:TMAR RS11790
gene id: 644966:TMAR_RS11790
uniprot id: E6SLI5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

644966:TMAR RS14510
gene id: 644966:TMAR_RS14510
uniprot id: E6SKE0
names: Similarity
messages: Belongs to the UPF0758 family.

644966:TMAR RS01635
gene id: 644966:TMAR_RS01635
uniprot id: E6SMG9
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

644966:TMAR RS08455
gene id: 644966:TMAR_RS08455
uniprot id: E6SHI4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

644966:TMAR RS11720
gene id: 644966:TMAR_RS11720
uniprot id: E6SLH3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS05190
gene id: 644966:TMAR_RS05190
uniprot id: E6SJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

644966:TMAR RS02955
gene id: 644966:TMAR_RS02955
uniprot id: E6SHD0
names: Similarity
messages: Belongs to the leucine-binding protein family.

644966:TMAR RS07965
gene id: 644966:TMAR_RS07965
uniprot id: E6SGU6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

644966:TMAR RS01870
gene id: 644966:TMAR_RS01870
uniprot id: E6SG60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

644966:TMAR RS01580
gene id: 644966:TMAR_RS01580
uniprot id: E6SMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

644966:TMAR RS04080
gene id: 644966:TMAR_RS04080
uniprot id: E6SIK7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

644966:TMAR RS10035
gene id: 644966:TMAR_RS10035
uniprot id: E6SJ77
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

644966:TMAR RS14635
gene id: 644966:TMAR_RS14635
uniprot id: E6SJB4
names: Similarity
messages: Belongs to the asp23 family.

644966:TMAR RS03535
gene id: 644966:TMAR_RS03535
uniprot id: E6SI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

644966:TMAR RS01905
gene id: 644966:TMAR_RS01905
uniprot id: E6SG67
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

644966:TMAR RS14815
gene id: 644966:TMAR_RS14815
uniprot id: E6SLY7
names: Similarity
messages: Belongs to the ParB family.

644966:TMAR RS01130
gene id: 644966:TMAR_RS01130
uniprot id: E6SLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

644966:TMAR RS09110
gene id: 644966:TMAR_RS09110
uniprot id: E6SIA5
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS03020
gene id: 644966:TMAR_RS03020
uniprot id: E6SHE3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

644966:TMAR RS01930
gene id: 644966:TMAR_RS01930
uniprot id: E6SG74
names: Similarity
messages: Belongs to the OsmC/Ohr family.

644966:TMAR RS11125
gene id: 644966:TMAR_RS11125
uniprot id: E6SKT6
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS01475
gene id: 644966:TMAR_RS01475
uniprot id: E6SMD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

644966:TMAR RS06365
gene id: 644966:TMAR_RS06365
uniprot id: E6SLR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

644966:TMAR RS11445
gene id: 644966:TMAR_RS11445
uniprot id: E6SKZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

644966:TMAR RS09300
gene id: 644966:TMAR_RS09300
uniprot id: E6SIE4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS04920
gene id: 644966:TMAR_RS04920
uniprot id: E6SJE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

644966:TMAR RS10840
gene id: 644966:TMAR_RS10840
uniprot id: E6SK99
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS06255
gene id: 644966:TMAR_RS06255
uniprot id: E6SLB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS11015
gene id: 644966:TMAR_RS11015
uniprot id: E6SKD2
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS04960
gene id: 644966:TMAR_RS04960
uniprot id: E6SJL9
names: Similarity
messages: Belongs to the DprA/Smf family.

644966:TMAR RS01700
gene id: 644966:TMAR_RS01700
uniprot id: E6SMI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

644966:TMAR RS14145
gene id: 644966:TMAR_RS14145
uniprot id: E6SJM7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

644966:TMAR RS00360
gene id: 644966:TMAR_RS00360
uniprot id: E6SKK7
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

644966:TMAR RS10800
gene id: 644966:TMAR_RS10800
uniprot id: E6SK91
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

644966:TMAR RS08340
gene id: 644966:TMAR_RS08340
uniprot id: E6SH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

644966:TMAR RS08315
gene id: 644966:TMAR_RS08315
uniprot id: E6SH87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

644966:TMAR RS11480
gene id: 644966:TMAR_RS11480
uniprot id: E6SLD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

644966:TMAR RS02755
gene id: 644966:TMAR_RS02755
uniprot id: E6SH23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

644966:TMAR RS03045
gene id: 644966:TMAR_RS03045
uniprot id: E6SHE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

644966:TMAR RS12385
gene id: 644966:TMAR_RS12385
uniprot id: E6SJJ2
names: Similarity
messages: Belongs to the Nth/MutY family.

644966:TMAR RS00510
gene id: 644966:TMAR_RS00510
uniprot id: E6SL12
names: Caution
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

644966:TMAR RS11715
gene id: 644966:TMAR_RS11715
uniprot id: E6SLH2
names: Similarity
messages: Belongs to the peptidase S49 family.

644966:TMAR RS02965
gene id: 644966:TMAR_RS02965
uniprot id: E6SHD2
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS06240
gene id: 644966:TMAR_RS06240
uniprot id: E6SLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

644966:TMAR RS01545
gene id: 644966:TMAR_RS01545
uniprot id: E6SMF1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

644966:TMAR RS10195
gene id: 644966:TMAR_RS10195
uniprot id: E6SJH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

644966:TMAR RS06950
gene id: 644966:TMAR_RS06950
uniprot id: E6SMB9
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS03260
gene id: 644966:TMAR_RS03260
uniprot id: E6SHQ7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

644966:TMAR RS04025
gene id: 644966:TMAR_RS04025
uniprot id: E6SIJ6
names: Subcellular Location Annotation
messages: Membrane

644966:TMAR RS11215
gene id: 644966:TMAR_RS11215
uniprot id: E6SKU8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

644966:TMAR RS06550
gene id: 644966:TMAR_RS06550
uniprot id: E6SLU9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

644966:TMAR RS02860
gene id: 644966:TMAR_RS02860
uniprot id: E6SHB1
names: Similarity
messages: Belongs to the EamA transporter family.

644966:TMAR RS03895
gene id: 644966:TMAR_RS03895
uniprot id: E6SIH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

644966:TMAR RS08120
gene id: 644966:TMAR_RS08120
uniprot id: E6SH47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

644966:TMAR RS10900
gene id: 644966:TMAR_RS10900
uniprot id: E6SKB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

644966:TMAR RS04345
gene id: 644966:TMAR_RS04345
uniprot id: E6SIW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

644966:TMAR RS09330
gene id: 644966:TMAR_RS09330
uniprot id: E6SIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

644966:TMAR RS05420
gene id: 644966:TMAR_RS05420
uniprot id: E6SK34
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

644966:TMAR RS11240
gene id: 644966:TMAR_RS11240
uniprot id: E6SKV3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

644966:TMAR RS09060
gene id: 644966:TMAR_RS09060
uniprot id: E6SI94
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

644966:TMAR RS00520
gene id: 644966:TMAR_RS00520
uniprot id: E6SL14
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

644966:TMAR RS02760
gene id: 644966:TMAR_RS02760
uniprot id: E6SH24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

644966:TMAR RS06400
gene id: 644966:TMAR_RS06400
uniprot id: E6SLR9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

644966:TMAR RS11060
gene id: 644966:TMAR_RS11060
uniprot id: E6SKE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

644966:TMAR RS09895
gene id: 644966:TMAR_RS09895
uniprot id: E6SJ48
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

644966:TMAR RS05790
gene id: 644966:TMAR_RS05790
uniprot id: E6SKP0
names: Similarity
messages: Belongs to the GerABKA family.

644966:TMAR RS03640
gene id: 644966:TMAR_RS03640
uniprot id: E6SI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

644966:TMAR RS14730
gene id: 644966:TMAR_RS14730
uniprot id: E6SMK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

644966:TMAR RS03385
gene id: 644966:TMAR_RS03385
uniprot id: E6SHT0
names: Similarity
messages: Belongs to the DinB family.

644966:TMAR RS03880
gene id: 644966:TMAR_RS03880
uniprot id: E6SIG7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

644966:TMAR RS04545
gene id: 644966:TMAR_RS04545
uniprot id: E6SJ04
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

644966:TMAR RS03780
gene id: 644966:TMAR_RS03780
uniprot id: E6SI75
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

644966:TMAR RS02010
gene id: 644966:TMAR_RS02010
uniprot id: E6SG90
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

644966:TMAR RS04295
gene id: 644966:TMAR_RS04295
uniprot id: E6SIV6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

644966:TMAR RS11450
gene id: 644966:TMAR_RS11450
uniprot id: E6SKZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

644966:TMAR RS01955
gene id: 644966:TMAR_RS01955
uniprot id: E6SG79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

644966:TMAR RS09245
gene id: 644966:TMAR_RS09245
uniprot id: E6SID1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

644966:TMAR RS05780
gene id: 644966:TMAR_RS05780
uniprot id: E6SKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.