643867:FTRAC RS12980
gene id: 643867:FTRAC_RS12980
uniprot id: E4TPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

643867:FTRAC RS13915
gene id: 643867:FTRAC_RS13915
uniprot id: E4TRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

643867:FTRAC RS15285
gene id: 643867:FTRAC_RS15285
uniprot id: E4TU10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

643867:FTRAC RS07040
gene id: 643867:FTRAC_RS07040
uniprot id: E4TMW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

643867:FTRAC RS06265
gene id: 643867:FTRAC_RS06265
uniprot id: E4TLB9
names: Similarity
messages: Belongs to the UPF0047 family.

643867:FTRAC RS03975
gene id: 643867:FTRAC_RS03975
uniprot id: E4TSH5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

643867:FTRAC RS06035
gene id: 643867:FTRAC_RS06035
uniprot id: E4TKN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643867:FTRAC RS03840
gene id: 643867:FTRAC_RS03840
uniprot id: E4TS16
names: Similarity
messages: Belongs to the phosphohexose mutase family.

643867:FTRAC RS11865
gene id: 643867:FTRAC_RS11865
uniprot id: E4TLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

643867:FTRAC RS12335
gene id: 643867:FTRAC_RS12335
uniprot id: E4TN31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM175 family.
messages: Cell membrane
messages: Homotetramer.
messages: Potassium channel; forms a potassium-permeable leak-like channel with weak selectivity for potassium (PubMed:32267231). The channel is permeable for K(+), Rb(+) and Cs(+) (PubMed:32267231).
messages: The six transmembrane regions are tightly packed within each subunit without undergoing domain swapping (PubMed:32267231). Transmembranes TM1-TM3 are positioned on the inner circle of the channel tetramer and participate in inter-subunit interactions that are central to the assembly of the ion conduction pore (PubMed:32267231). The RxxxFSD motif within transmembrane TM1 coordinates a network of specific inter- and intra-subunit interactions with other conserved residues on TM2 and TM3 and plays a key role in the tetrameric assembly of the channel (PubMed:32267231). Transmembrane TM4-TM6 are positioned on the periphery of the channel and do not contribute to contacts with neighboring subunits (By similarity). Transmembrane TM1 forms the pore-lining inner helix at the center of the channel, creating an hourglass-shaped ion permeation pathway in the channel tetramer (By similarity). Hydrophobic residues (Leu-35, Leu-39 and Leu-42) on the C-terminal half of the TM1 helix form a bottleneck along the ion conduction pathway and serve as the selectivity filter of the channel (PubMed:32267231). Thr-38 is required for potassium ion selectivity (PubMed:32267231).

643867:FTRAC RS05220
gene id: 643867:FTRAC_RS05220
uniprot id: E4TUA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

643867:FTRAC RS01910
gene id: 643867:FTRAC_RS01910
uniprot id: E4TMT8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

643867:FTRAC RS15205
gene id: 643867:FTRAC_RS15205
uniprot id: E4TTZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

643867:FTRAC RS16980
gene id: 643867:FTRAC_RS16980
uniprot id: E4TLU5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

643867:FTRAC RS03610
gene id: 643867:FTRAC_RS03610
uniprot id: E4TRW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS11885
gene id: 643867:FTRAC_RS11885
uniprot id: E4TM97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

643867:FTRAC RS14325
gene id: 643867:FTRAC_RS14325
uniprot id: E4TSC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

643867:FTRAC RS13145
gene id: 643867:FTRAC_RS13145
uniprot id: E4TPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS12455
gene id: 643867:FTRAC_RS12455
uniprot id: E4TN56
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS08880
gene id: 643867:FTRAC_RS08880
uniprot id: E4TRN5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

643867:FTRAC RS07165
gene id: 643867:FTRAC_RS07165
uniprot id: E4TMZ0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS18780
gene id: 643867:FTRAC_RS18780
uniprot id: E4TR78
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

643867:FTRAC RS03560
gene id: 643867:FTRAC_RS03560
uniprot id: E4TRH7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS08145
gene id: 643867:FTRAC_RS08145
uniprot id: E4TQ69
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

643867:FTRAC RS04955
gene id: 643867:FTRAC_RS04955
uniprot id: E4TU56
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

643867:FTRAC RS12950
gene id: 643867:FTRAC_RS12950
uniprot id: E4TPK5
names: Similarity
messages: Belongs to the Nth/MutY family.

643867:FTRAC RS05705
gene id: 643867:FTRAC_RS05705
uniprot id: E4TVL8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

643867:FTRAC RS08905
gene id: 643867:FTRAC_RS08905
uniprot id: E4TRP0
names: Similarity
messages: Belongs to the Skp family.

643867:FTRAC RS16300
gene id: 643867:FTRAC_RS16300
uniprot id: E4TW17
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS02545
gene id: 643867:FTRAC_RS02545
uniprot id: E4TPA8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

643867:FTRAC RS13385
gene id: 643867:FTRAC_RS13385
uniprot id: E4TQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS00215
gene id: 643867:FTRAC_RS00215
uniprot id: E4TUT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

643867:FTRAC RS04280
gene id: 643867:FTRAC_RS04280
uniprot id: E4TT04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

643867:FTRAC RS15420
gene id: 643867:FTRAC_RS15420
uniprot id: E4TU36
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS08495
gene id: 643867:FTRAC_RS08495
uniprot id: E4TQY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS04805
gene id: 643867:FTRAC_RS04805
uniprot id: E4TTN9
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS10885
gene id: 643867:FTRAC_RS10885
uniprot id: E4TVR4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS04460
gene id: 643867:FTRAC_RS04460
uniprot id: E4TT39
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS00175
gene id: 643867:FTRAC_RS00175
uniprot id: E4TUS3
names: Similarity
messages: Belongs to the fructosamine kinase family.

643867:FTRAC RS01010
gene id: 643867:FTRAC_RS01010
uniprot id: E4TL69
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS18445
gene id: 643867:FTRAC_RS18445
uniprot id: E4TQG8
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS11265
gene id: 643867:FTRAC_RS11265
uniprot id: E4TKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

643867:FTRAC RS04215
gene id: 643867:FTRAC_RS04215
uniprot id: E4TSL9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

643867:FTRAC RS08710
gene id: 643867:FTRAC_RS08710
uniprot id: E4TRK0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

643867:FTRAC RS12545
gene id: 643867:FTRAC_RS12545
uniprot id: E4TNS4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

643867:FTRAC RS14870
gene id: 643867:FTRAC_RS14870
uniprot id: E4TTE9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

643867:FTRAC RS04455
gene id: 643867:FTRAC_RS04455
uniprot id: E4TT38
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

643867:FTRAC RS14705
gene id: 643867:FTRAC_RS14705
uniprot id: E4TSX7
names: Subcellular Location Annotation
messages: Secreted

643867:FTRAC RS11295
gene id: 643867:FTRAC_RS11295
uniprot id: E4TKT8
names: Similarity
messages: Belongs to the peptidase S8 family.

643867:FTRAC RS00490
gene id: 643867:FTRAC_RS00490
uniprot id: E4TVH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

643867:FTRAC RS00715
gene id: 643867:FTRAC_RS00715
uniprot id: E4TKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

643867:FTRAC RS07420
gene id: 643867:FTRAC_RS07420
uniprot id: E4TNN5
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS18890
gene id: 643867:FTRAC_RS18890
uniprot id: E4TR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS18390
gene id: 643867:FTRAC_RS18390
uniprot id: E4TPW3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

643867:FTRAC RS15675
gene id: 643867:FTRAC_RS15675
uniprot id: E4TUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

643867:FTRAC RS03910
gene id: 643867:FTRAC_RS03910
uniprot id: E4TSG2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

643867:FTRAC RS04570
gene id: 643867:FTRAC_RS04570
uniprot id: E4TT62
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

643867:FTRAC RS11415
gene id: 643867:FTRAC_RS11415
uniprot id: E4TKW1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS14085
gene id: 643867:FTRAC_RS14085
uniprot id: E4TRU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS11640
gene id: 643867:FTRAC_RS11640
uniprot id: E4TLK3
names: Similarity
messages: Belongs to the HypE family.

643867:FTRAC RS12290
gene id: 643867:FTRAC_RS12290
uniprot id: E4TN22
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

643867:FTRAC RS03055
gene id: 643867:FTRAC_RS03055
uniprot id: E4TQQ0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643867:FTRAC RS02745
gene id: 643867:FTRAC_RS02745
uniprot id: E4TPZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

643867:FTRAC RS05090
gene id: 643867:FTRAC_RS05090
uniprot id: E4TU81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS08635
gene id: 643867:FTRAC_RS08635
uniprot id: E4TRI5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS10290
gene id: 643867:FTRAC_RS10290
uniprot id: E4TUC2
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS17325
gene id: 643867:FTRAC_RS17325
uniprot id: E4TMK6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

643867:FTRAC RS14445
gene id: 643867:FTRAC_RS14445
uniprot id: E4TSF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

643867:FTRAC RS14220
gene id: 643867:FTRAC_RS14220
uniprot id: E4TSA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS05225
gene id: 643867:FTRAC_RS05225
uniprot id: E4TUA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

643867:FTRAC RS16815
gene id: 643867:FTRAC_RS16815
uniprot id: E4TLR2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

643867:FTRAC RS13240
gene id: 643867:FTRAC_RS13240
uniprot id: E4TQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

643867:FTRAC RS15185
gene id: 643867:FTRAC_RS15185
uniprot id: E4TTY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

643867:FTRAC RS12900
gene id: 643867:FTRAC_RS12900
uniprot id: E4TPJ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS05865
gene id: 643867:FTRAC_RS05865
uniprot id: E4TVQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

643867:FTRAC RS11480
gene id: 643867:FTRAC_RS11480
uniprot id: E4TKX5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

643867:FTRAC RS12345
gene id: 643867:FTRAC_RS12345
uniprot id: E4TN33
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS01960
gene id: 643867:FTRAC_RS01960
uniprot id: E4TNE0
names: Similarity
messages: Belongs to the peptidase S41A family.

643867:FTRAC RS04985
gene id: 643867:FTRAC_RS04985
uniprot id: E4TU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS15690
gene id: 643867:FTRAC_RS15690
uniprot id: E4TUL8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

643867:FTRAC RS11450
gene id: 643867:FTRAC_RS11450
uniprot id: E4TKW9
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS03820
gene id: 643867:FTRAC_RS03820
uniprot id: E4TS12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643867:FTRAC RS16820
gene id: 643867:FTRAC_RS16820
uniprot id: E4TLR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

643867:FTRAC RS10230
gene id: 643867:FTRAC_RS10230
uniprot id: E4TTX3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).

643867:FTRAC RS02825
gene id: 643867:FTRAC_RS02825
uniprot id: E4TQ11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643867:FTRAC RS05465
gene id: 643867:FTRAC_RS05465
uniprot id: E4TUX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

643867:FTRAC RS10040
gene id: 643867:FTRAC_RS10040
uniprot id: E4TTT4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

643867:FTRAC RS17690
gene id: 643867:FTRAC_RS17690
uniprot id: E4TNC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643867:FTRAC RS12245
gene id: 643867:FTRAC_RS12245
uniprot id: E4TN13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

643867:FTRAC RS00610
gene id: 643867:FTRAC_RS00610
uniprot id: E4TKE9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

643867:FTRAC RS09125
gene id: 643867:FTRAC_RS09125
uniprot id: E4TS65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

643867:FTRAC RS10900
gene id: 643867:FTRAC_RS10900
uniprot id: E4TVR7
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS08860
gene id: 643867:FTRAC_RS08860
uniprot id: E4TRN0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS02660
gene id: 643867:FTRAC_RS02660
uniprot id: E4TPX9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

643867:FTRAC RS08190
gene id: 643867:FTRAC_RS08190
uniprot id: E4TQ79
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.

643867:FTRAC RS10280
gene id: 643867:FTRAC_RS10280
uniprot id: E4TUC0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS06330
gene id: 643867:FTRAC_RS06330
uniprot id: E4TLD2
names: Similarity
messages: Belongs to the AHA1 family.

643867:FTRAC RS03470
gene id: 643867:FTRAC_RS03470
uniprot id: E4TRF9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

643867:FTRAC RS12525
gene id: 643867:FTRAC_RS12525
uniprot id: E4TNS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643867:FTRAC RS12045
gene id: 643867:FTRAC_RS12045
uniprot id: E4TMC9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

643867:FTRAC RS18800
gene id: 643867:FTRAC_RS18800
uniprot id: E4TR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

643867:FTRAC RS09275
gene id: 643867:FTRAC_RS09275
uniprot id: E4TSM5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

643867:FTRAC RS19360
gene id: 643867:FTRAC_RS19360
uniprot id: E4TQE5
names: Similarity
messages: Belongs to the UPF0438 family.

643867:FTRAC RS12330
gene id: 643867:FTRAC_RS12330
uniprot id: E4TN30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

643867:FTRAC RS07185
gene id: 643867:FTRAC_RS07185
uniprot id: E4TMZ4
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS13835
gene id: 643867:FTRAC_RS13835
uniprot id: E4TRP6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

643867:FTRAC RS04300
gene id: 643867:FTRAC_RS04300
uniprot id: E4TT08
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

643867:FTRAC RS12750
gene id: 643867:FTRAC_RS12750
uniprot id: E4TNW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

643867:FTRAC RS08410
gene id: 643867:FTRAC_RS08410
uniprot id: E4TQW4
names: Similarity
messages: Belongs to the peptidase S41A family.

643867:FTRAC RS15230
gene id: 643867:FTRAC_RS15230
uniprot id: E4TTZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

643867:FTRAC RS11820
gene id: 643867:FTRAC_RS11820
uniprot id: E4TLN9
names: Similarity
messages: Belongs to the UPF0175 family.

643867:FTRAC RS04615
gene id: 643867:FTRAC_RS04615
uniprot id: E4TTK2
names: Similarity
messages: Belongs to the DEAD box helicase family.

643867:FTRAC RS16915
gene id: 643867:FTRAC_RS16915
uniprot id: E4TLT3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

643867:FTRAC RS09670
gene id: 643867:FTRAC_RS09670
uniprot id: E4TT84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

643867:FTRAC RS16955
gene id: 643867:FTRAC_RS16955
uniprot id: E4TLU0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16775
gene id: 643867:FTRAC_RS16775
uniprot id: E4TLQ3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

643867:FTRAC RS16925
gene id: 643867:FTRAC_RS16925
uniprot id: E4TLT5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS14945
gene id: 643867:FTRAC_RS14945
uniprot id: E4TTG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

643867:FTRAC RS01650
gene id: 643867:FTRAC_RS01650
uniprot id: E4TMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643867:FTRAC RS12655
gene id: 643867:FTRAC_RS12655
uniprot id: E4TNU5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

643867:FTRAC RS09555
gene id: 643867:FTRAC_RS09555
uniprot id: E4TST2
names: Similarity
messages: Belongs to the ComB family.

643867:FTRAC RS09400
gene id: 643867:FTRAC_RS09400
uniprot id: E4TSQ0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16005
gene id: 643867:FTRAC_RS16005
uniprot id: E4TVB0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

643867:FTRAC RS07715
gene id: 643867:FTRAC_RS07715
uniprot id: E4TPE2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS00110
gene id: 643867:FTRAC_RS00110
uniprot id: E4TUR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

643867:FTRAC RS09395
gene id: 643867:FTRAC_RS09395
uniprot id: E4TSP9
names: Similarity
messages: Belongs to the DEAD box helicase family.

643867:FTRAC RS15600
gene id: 643867:FTRAC_RS15600
uniprot id: E4TUK1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643867:FTRAC RS03905
gene id: 643867:FTRAC_RS03905
uniprot id: E4TSG1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS12945
gene id: 643867:FTRAC_RS12945
uniprot id: E4TPK4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS05230
gene id: 643867:FTRAC_RS05230
uniprot id: E4TUA9
names: Similarity
messages: Belongs to the TrpF family.

643867:FTRAC RS18990
gene id: 643867:FTRAC_RS18990
uniprot id: E4TW48
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

643867:FTRAC RS12905
gene id: 643867:FTRAC_RS12905
uniprot id: E4TPJ6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

643867:FTRAC RS07135
gene id: 643867:FTRAC_RS07135
uniprot id: E4TMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

643867:FTRAC RS14315
gene id: 643867:FTRAC_RS14315
uniprot id: E4TSC4
names: Similarity
messages: Belongs to the threonine synthase family.

643867:FTRAC RS16570
gene id: 643867:FTRAC_RS16570
uniprot id: E4TL12
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04530
gene id: 643867:FTRAC_RS04530
uniprot id: E4TT53
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS15405
gene id: 643867:FTRAC_RS15405
uniprot id: E4TU33
names: Similarity
messages: Belongs to the asparagine synthetase family.

643867:FTRAC RS08590
gene id: 643867:FTRAC_RS08590
uniprot id: E4TQZ8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

643867:FTRAC RS10125
gene id: 643867:FTRAC_RS10125
uniprot id: E4TTV1
names: Similarity
messages: Belongs to the AIR synthase family.

643867:FTRAC RS02230
gene id: 643867:FTRAC_RS02230
uniprot id: E4TNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS02365
gene id: 643867:FTRAC_RS02365
uniprot id: E4TP74
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

643867:FTRAC RS13025
gene id: 643867:FTRAC_RS13025
uniprot id: E4TPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

643867:FTRAC RS03725
gene id: 643867:FTRAC_RS03725
uniprot id: E4TRZ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

643867:FTRAC RS18380
gene id: 643867:FTRAC_RS18380
uniprot id: E4TPW1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

643867:FTRAC RS15130
gene id: 643867:FTRAC_RS15130
uniprot id: E4TTX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

643867:FTRAC RS03165
gene id: 643867:FTRAC_RS03165
uniprot id: E4TQS1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS15240
gene id: 643867:FTRAC_RS15240
uniprot id: E4TU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

643867:FTRAC RS11565
gene id: 643867:FTRAC_RS11565
uniprot id: E4TLI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS13355
gene id: 643867:FTRAC_RS13355
uniprot id: E4TQC6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

643867:FTRAC RS04285
gene id: 643867:FTRAC_RS04285
uniprot id: E4TT05
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

643867:FTRAC RS05040
gene id: 643867:FTRAC_RS05040
uniprot id: E4TU72
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

643867:FTRAC RS08985
gene id: 643867:FTRAC_RS08985
uniprot id: E4TS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

643867:FTRAC RS15115
gene id: 643867:FTRAC_RS15115
uniprot id: E4TTJ4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

643867:FTRAC RS07915
gene id: 643867:FTRAC_RS07915
uniprot id: E4TPI1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

643867:FTRAC RS08805
gene id: 643867:FTRAC_RS08805
uniprot id: E4TRL9
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

643867:FTRAC RS18200
gene id: 643867:FTRAC_RS18200
uniprot id: E4TPS3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

643867:FTRAC RS03895
gene id: 643867:FTRAC_RS03895
uniprot id: E4TSF8
names: Similarity
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.

643867:FTRAC RS01090
gene id: 643867:FTRAC_RS01090
uniprot id: E4TL86
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16420
gene id: 643867:FTRAC_RS16420
uniprot id: E4TW41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

643867:FTRAC RS03310
gene id: 643867:FTRAC_RS03310
uniprot id: E4TRC7
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS15180
gene id: 643867:FTRAC_RS15180
uniprot id: E4TTY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

643867:FTRAC RS17810
gene id: 643867:FTRAC_RS17810
uniprot id: E4TP00
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

643867:FTRAC RS04855
gene id: 643867:FTRAC_RS04855
uniprot id: E4TTP9
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

643867:FTRAC RS02290
gene id: 643867:FTRAC_RS02290
uniprot id: E4TP60
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

643867:FTRAC RS19245
gene id: 643867:FTRAC_RS19245
uniprot id: E4TMZ6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

643867:FTRAC RS08330
gene id: 643867:FTRAC_RS08330
uniprot id: E4TQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643867:FTRAC RS01125
gene id: 643867:FTRAC_RS01125
uniprot id: E4TL93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS15235
gene id: 643867:FTRAC_RS15235
uniprot id: E4TTZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

643867:FTRAC RS12490
gene id: 643867:FTRAC_RS12490
uniprot id: E4TN63
names: Similarity
messages: Belongs to the LOG family.

643867:FTRAC RS04110
gene id: 643867:FTRAC_RS04110
uniprot id: E4TSJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

643867:FTRAC RS09995
gene id: 643867:FTRAC_RS09995
uniprot id: E4TTS4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

643867:FTRAC RS00505
gene id: 643867:FTRAC_RS00505
uniprot id: E4TVH9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

643867:FTRAC RS12070
gene id: 643867:FTRAC_RS12070
uniprot id: E4TMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS04515
gene id: 643867:FTRAC_RS04515
uniprot id: E4TT50
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

643867:FTRAC RS06420
gene id: 643867:FTRAC_RS06420
uniprot id: E4TLF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643867:FTRAC RS05805
gene id: 643867:FTRAC_RS05805
uniprot id: E4TVN8
names: Subcellular Location Annotation
messages: Cytoplasm

643867:FTRAC RS13090
gene id: 643867:FTRAC_RS13090
uniprot id: E4TPN3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

643867:FTRAC RS05430
gene id: 643867:FTRAC_RS05430
uniprot id: E4TUX1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS08420
gene id: 643867:FTRAC_RS08420
uniprot id: E4TQW6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

643867:FTRAC RS03390
gene id: 643867:FTRAC_RS03390
uniprot id: E4TRE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

643867:FTRAC RS15065
gene id: 643867:FTRAC_RS15065
uniprot id: E4TTI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

643867:FTRAC RS06635
gene id: 643867:FTRAC_RS06635
uniprot id: E4TM40
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS02765
gene id: 643867:FTRAC_RS02765
uniprot id: E4TPZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

643867:FTRAC RS09210
gene id: 643867:FTRAC_RS09210
uniprot id: E4TS82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

643867:FTRAC RS02430
gene id: 643867:FTRAC_RS02430
uniprot id: E4TP87
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS08225
gene id: 643867:FTRAC_RS08225
uniprot id: E4TQ87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

643867:FTRAC RS10630
gene id: 643867:FTRAC_RS10630
uniprot id: E4TV16
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS16555
gene id: 643867:FTRAC_RS16555
uniprot id: E4TL09
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

643867:FTRAC RS18570
gene id: 643867:FTRAC_RS18570
uniprot id: E4TQJ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

643867:FTRAC RS10560
gene id: 643867:FTRAC_RS10560
uniprot id: E4TUH5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS08690
gene id: 643867:FTRAC_RS08690
uniprot id: E4TRJ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

643867:FTRAC RS16595
gene id: 643867:FTRAC_RS16595
uniprot id: E4TL17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

643867:FTRAC RS18440
gene id: 643867:FTRAC_RS18440
uniprot id: E4TQG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

643867:FTRAC RS16990
gene id: 643867:FTRAC_RS16990
uniprot id: E4TLU7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

643867:FTRAC RS01005
gene id: 643867:FTRAC_RS01005
uniprot id: E4TL68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS10725
gene id: 643867:FTRAC_RS10725
uniprot id: E4TV35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS18435
gene id: 643867:FTRAC_RS18435
uniprot id: E4TQG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

643867:FTRAC RS10880
gene id: 643867:FTRAC_RS10880
uniprot id: E4TVR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS08685
gene id: 643867:FTRAC_RS08685
uniprot id: E4TRJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

643867:FTRAC RS05190
gene id: 643867:FTRAC_RS05190
uniprot id: E4TUA1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643867:FTRAC RS15140
gene id: 643867:FTRAC_RS15140
uniprot id: E4TTY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643867:FTRAC RS17800
gene id: 643867:FTRAC_RS17800
uniprot id: E4TNZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643867:FTRAC RS00485
gene id: 643867:FTRAC_RS00485
uniprot id: E4TVH5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

643867:FTRAC RS11470
gene id: 643867:FTRAC_RS11470
uniprot id: E4TKX3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

643867:FTRAC RS10005
gene id: 643867:FTRAC_RS10005
uniprot id: E4TTS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

643867:FTRAC RS10770
gene id: 643867:FTRAC_RS10770
uniprot id: E4TV45
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

643867:FTRAC RS03920
gene id: 643867:FTRAC_RS03920
uniprot id: E4TSG4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

643867:FTRAC RS10090
gene id: 643867:FTRAC_RS10090
uniprot id: E4TTU3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

643867:FTRAC RS13030
gene id: 643867:FTRAC_RS13030
uniprot id: E4TPM1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS05185
gene id: 643867:FTRAC_RS05185
uniprot id: E4TUA0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

643867:FTRAC RS03100
gene id: 643867:FTRAC_RS03100
uniprot id: E4TQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

643867:FTRAC RS15280
gene id: 643867:FTRAC_RS15280
uniprot id: E4TU09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

643867:FTRAC RS01600
gene id: 643867:FTRAC_RS01600
uniprot id: E4TMM9
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

643867:FTRAC RS00305
gene id: 643867:FTRAC_RS00305
uniprot id: E4TVE6
names: Similarity
messages: Belongs to the glutamine synthetase family.

643867:FTRAC RS18460
gene id: 643867:FTRAC_RS18460
uniprot id: E4TQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS09665
gene id: 643867:FTRAC_RS09665
uniprot id: E4TT83
names: Similarity
messages: Belongs to the BshC family.

643867:FTRAC RS02460
gene id: 643867:FTRAC_RS02460
uniprot id: E4TP93
names: Similarity
messages: Belongs to the peptidase U62 family.

643867:FTRAC RS18260
gene id: 643867:FTRAC_RS18260
uniprot id: E4TPT5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

643867:FTRAC RS06375
gene id: 643867:FTRAC_RS06375
uniprot id: E4TLE1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

643867:FTRAC RS18775
gene id: 643867:FTRAC_RS18775
uniprot id: E4TR77
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

643867:FTRAC RS11205
gene id: 643867:FTRAC_RS11205
uniprot id: E4TVX5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

643867:FTRAC RS10080
gene id: 643867:FTRAC_RS10080
uniprot id: E4TTU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS03745
gene id: 643867:FTRAC_RS03745
uniprot id: E4TRZ7
names: Similarity
messages: Belongs to the histone deacetylase family.

643867:FTRAC RS02435
gene id: 643867:FTRAC_RS02435
uniprot id: E4TP88
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS14550
gene id: 643867:FTRAC_RS14550
uniprot id: E4TSU7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

643867:FTRAC RS03305
gene id: 643867:FTRAC_RS03305
uniprot id: E4TRC6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

643867:FTRAC RS17125
gene id: 643867:FTRAC_RS17125
uniprot id: E4TMG8
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS05015
gene id: 643867:FTRAC_RS05015
uniprot id: E4TU67
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04120
gene id: 643867:FTRAC_RS04120
uniprot id: E4TSK0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

643867:FTRAC RS05305
gene id: 643867:FTRAC_RS05305
uniprot id: E4TUU7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

643867:FTRAC RS17940
gene id: 643867:FTRAC_RS17940
uniprot id: E4TP26
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

643867:FTRAC RS02840
gene id: 643867:FTRAC_RS02840
uniprot id: E4TQ14
names: Similarity
messages: Belongs to the thioredoxin family.

643867:FTRAC RS15070
gene id: 643867:FTRAC_RS15070
uniprot id: E4TTI9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS17560
gene id: 643867:FTRAC_RS17560
uniprot id: E4TN95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643867:FTRAC RS02620
gene id: 643867:FTRAC_RS02620
uniprot id: E4TPX0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

643867:FTRAC RS08185
gene id: 643867:FTRAC_RS08185
uniprot id: E4TQ78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

643867:FTRAC RS16660
gene id: 643867:FTRAC_RS16660
uniprot id: E4TL30
names: Similarity
messages: Belongs to the transglycosylase Slt family.

643867:FTRAC RS07355
gene id: 643867:FTRAC_RS07355
uniprot id: E4TNM2
names: Similarity
messages: Belongs to the sterol desaturase family.

643867:FTRAC RS12425
gene id: 643867:FTRAC_RS12425
uniprot id: E4TN50
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS10115
gene id: 643867:FTRAC_RS10115
uniprot id: E4TTU9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643867:FTRAC RS02445
gene id: 643867:FTRAC_RS02445
uniprot id: E4TP90
names: Similarity
messages: Belongs to the DEAD box helicase family.

643867:FTRAC RS09945
gene id: 643867:FTRAC_RS09945
uniprot id: E4TTR4
names: Similarity
messages: Belongs to the pirin family.

643867:FTRAC RS06120
gene id: 643867:FTRAC_RS06120
uniprot id: E4TKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

643867:FTRAC RS05700
gene id: 643867:FTRAC_RS05700
uniprot id: E4TVL7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS14880
gene id: 643867:FTRAC_RS14880
uniprot id: E4TTF1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS01100
gene id: 643867:FTRAC_RS01100
uniprot id: E4TL88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

643867:FTRAC RS11940
gene id: 643867:FTRAC_RS11940
uniprot id: E4TMA8
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

643867:FTRAC RS07580
gene id: 643867:FTRAC_RS07580
uniprot id: E4TNR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS18695
gene id: 643867:FTRAC_RS18695
uniprot id: E4TQM0
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

643867:FTRAC RS12605
gene id: 643867:FTRAC_RS12605
uniprot id: E4TNT5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

643867:FTRAC RS16745
gene id: 643867:FTRAC_RS16745
uniprot id: E4TL49
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

643867:FTRAC RS00345
gene id: 643867:FTRAC_RS00345
uniprot id: E4TVF2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

643867:FTRAC RS03500
gene id: 643867:FTRAC_RS03500
uniprot id: E4TRG5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

643867:FTRAC RS07780
gene id: 643867:FTRAC_RS07780
uniprot id: E4TPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

643867:FTRAC RS10605
gene id: 643867:FTRAC_RS10605
uniprot id: E4TV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS00050
gene id: 643867:FTRAC_RS00050
uniprot id: E4TUP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

643867:FTRAC RS18345
gene id: 643867:FTRAC_RS18345
uniprot id: E4TPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

643867:FTRAC RS09365
gene id: 643867:FTRAC_RS09365
uniprot id: E4TSP3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

643867:FTRAC RS10685
gene id: 643867:FTRAC_RS10685
uniprot id: E4TV27
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS12530
gene id: 643867:FTRAC_RS12530
uniprot id: E4TNS1
names: Similarity
messages: Belongs to the aspartokinase family.

643867:FTRAC RS13710
gene id: 643867:FTRAC_RS13710
uniprot id: E4TR40
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

643867:FTRAC RS15200
gene id: 643867:FTRAC_RS15200
uniprot id: E4TTZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

643867:FTRAC RS15225
gene id: 643867:FTRAC_RS15225
uniprot id: E4TTZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

643867:FTRAC RS03355
gene id: 643867:FTRAC_RS03355
uniprot id: E4TRD7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS09160
gene id: 643867:FTRAC_RS09160
uniprot id: E4TS72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS09610
gene id: 643867:FTRAC_RS09610
uniprot id: E4TT73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

643867:FTRAC RS11380
gene id: 643867:FTRAC_RS11380
uniprot id: E4TKV4
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16445
gene id: 643867:FTRAC_RS16445
uniprot id: E4TKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS00140
gene id: 643867:FTRAC_RS00140
uniprot id: E4TUR6
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16070
gene id: 643867:FTRAC_RS16070
uniprot id: E4TVC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

643867:FTRAC RS12840
gene id: 643867:FTRAC_RS12840
uniprot id: E4TNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

643867:FTRAC RS17660
gene id: 643867:FTRAC_RS17660
uniprot id: E4TNB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

643867:FTRAC RS08610
gene id: 643867:FTRAC_RS08610
uniprot id: E4TRI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

643867:FTRAC RS03980
gene id: 643867:FTRAC_RS03980
uniprot id: E4TSH6
names: Similarity
messages: Belongs to the PGI/PMI family.

643867:FTRAC RS09315
gene id: 643867:FTRAC_RS09315
uniprot id: E4TSN3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

643867:FTRAC RS05125
gene id: 643867:FTRAC_RS05125
uniprot id: E4TU88
names: Cofactor
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS19905
gene id: 643867:FTRAC_RS19905
uniprot id: E4TMY1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

643867:FTRAC RS13845
gene id: 643867:FTRAC_RS13845
uniprot id: E4TRP8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

643867:FTRAC RS16740
gene id: 643867:FTRAC_RS16740
uniprot id: E4TL47
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04525
gene id: 643867:FTRAC_RS04525
uniprot id: E4TT52
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

643867:FTRAC RS09565
gene id: 643867:FTRAC_RS09565
uniprot id: E4TT64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

643867:FTRAC RS10110
gene id: 643867:FTRAC_RS10110
uniprot id: E4TTU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

643867:FTRAC RS10265
gene id: 643867:FTRAC_RS10265
uniprot id: E4TUB7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

643867:FTRAC RS03395
gene id: 643867:FTRAC_RS03395
uniprot id: E4TRE5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

643867:FTRAC RS05890
gene id: 643867:FTRAC_RS05890
uniprot id: E4TVQ5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

643867:FTRAC RS17655
gene id: 643867:FTRAC_RS17655
uniprot id: E4TNB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

643867:FTRAC RS15305
gene id: 643867:FTRAC_RS15305
uniprot id: E4TU14
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

643867:FTRAC RS05975
gene id: 643867:FTRAC_RS05975
uniprot id: E4TKL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS14050
gene id: 643867:FTRAC_RS14050
uniprot id: E4TRT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

643867:FTRAC RS00975
gene id: 643867:FTRAC_RS00975
uniprot id: E4TL62
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

643867:FTRAC RS16250
gene id: 643867:FTRAC_RS16250
uniprot id: E4TW07
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

643867:FTRAC RS15190
gene id: 643867:FTRAC_RS15190
uniprot id: E4TTZ0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

643867:FTRAC RS18535
gene id: 643867:FTRAC_RS18535
uniprot id: E4TQI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS06285
gene id: 643867:FTRAC_RS06285
uniprot id: E4TLC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

643867:FTRAC RS06885
gene id: 643867:FTRAC_RS06885
uniprot id: E4TM90
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS05875
gene id: 643867:FTRAC_RS05875
uniprot id: E4TVQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS12185
gene id: 643867:FTRAC_RS12185
uniprot id: E4TMF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

643867:FTRAC RS18005
gene id: 643867:FTRAC_RS18005
uniprot id: E4TP39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

643867:FTRAC RS15955
gene id: 643867:FTRAC_RS15955
uniprot id: E4TVA0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

643867:FTRAC RS02420
gene id: 643867:FTRAC_RS02420
uniprot id: E4TP85
names: Similarity
messages: Belongs to the ArsC family.

643867:FTRAC RS12855
gene id: 643867:FTRAC_RS12855
uniprot id: E4TPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

643867:FTRAC RS03465
gene id: 643867:FTRAC_RS03465
uniprot id: E4TRF8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS05055
gene id: 643867:FTRAC_RS05055
uniprot id: E4TU74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

643867:FTRAC RS06240
gene id: 643867:FTRAC_RS06240
uniprot id: E4TKR8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS07545
gene id: 643867:FTRAC_RS07545
uniprot id: E4TNQ9
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

643867:FTRAC RS13110
gene id: 643867:FTRAC_RS13110
uniprot id: E4TPN7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

643867:FTRAC RS12955
gene id: 643867:FTRAC_RS12955
uniprot id: E4TPK6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

643867:FTRAC RS03195
gene id: 643867:FTRAC_RS03195
uniprot id: E4TQS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

643867:FTRAC RS11245
gene id: 643867:FTRAC_RS11245
uniprot id: E4TKS8
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS07795
gene id: 643867:FTRAC_RS07795
uniprot id: E4TPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

643867:FTRAC RS05745
gene id: 643867:FTRAC_RS05745
uniprot id: E4TVM5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

643867:FTRAC RS14835
gene id: 643867:FTRAC_RS14835
uniprot id: E4TTE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

643867:FTRAC RS00070
gene id: 643867:FTRAC_RS00070
uniprot id: E4TUQ2
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04005
gene id: 643867:FTRAC_RS04005
uniprot id: E4TSI1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

643867:FTRAC RS18250
gene id: 643867:FTRAC_RS18250
uniprot id: E4TPT3
names: Cofactor
messages: Can also use Mn(2+) ion.

643867:FTRAC RS03645
gene id: 643867:FTRAC_RS03645
uniprot id: E4TRX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

643867:FTRAC RS03835
gene id: 643867:FTRAC_RS03835
uniprot id: E4TS15
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

643867:FTRAC RS11390
gene id: 643867:FTRAC_RS11390
uniprot id: E4TKV6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643867:FTRAC RS13405
gene id: 643867:FTRAC_RS13405
uniprot id: E4TQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

643867:FTRAC RS13905
gene id: 643867:FTRAC_RS13905
uniprot id: E4TRR0
names: Subunit
messages: Monomer.

643867:FTRAC RS06475
gene id: 643867:FTRAC_RS06475
uniprot id: E4TLG2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

643867:FTRAC RS09290
gene id: 643867:FTRAC_RS09290
uniprot id: E4TSM8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

643867:FTRAC RS07370
gene id: 643867:FTRAC_RS07370
uniprot id: E4TNM5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

643867:FTRAC RS00685
gene id: 643867:FTRAC_RS00685
uniprot id: E4TKG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS04175
gene id: 643867:FTRAC_RS04175
uniprot id: E4TSL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643867:FTRAC RS06805
gene id: 643867:FTRAC_RS06805
uniprot id: E4TM74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

643867:FTRAC RS05195
gene id: 643867:FTRAC_RS05195
uniprot id: E4TUA2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS16625
gene id: 643867:FTRAC_RS16625
uniprot id: E4TL23
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

643867:FTRAC RS18785
gene id: 643867:FTRAC_RS18785
uniprot id: E4TR79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

643867:FTRAC RS03480
gene id: 643867:FTRAC_RS03480
uniprot id: E4TRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS03855
gene id: 643867:FTRAC_RS03855
uniprot id: E4TS19
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

643867:FTRAC RS08080
gene id: 643867:FTRAC_RS08080
uniprot id: E4TQ56
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS07250
gene id: 643867:FTRAC_RS07250
uniprot id: E4TNK1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

643867:FTRAC RS03385
gene id: 643867:FTRAC_RS03385
uniprot id: E4TRE3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

643867:FTRAC RS13100
gene id: 643867:FTRAC_RS13100
uniprot id: E4TPN5
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS12680
gene id: 643867:FTRAC_RS12680
uniprot id: E4TNV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643867:FTRAC RS08525
gene id: 643867:FTRAC_RS08525
uniprot id: E4TQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

643867:FTRAC RS10345
gene id: 643867:FTRAC_RS10345
uniprot id: E4TUD4
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS15195
gene id: 643867:FTRAC_RS15195
uniprot id: E4TTZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

643867:FTRAC RS01410
gene id: 643867:FTRAC_RS01410
uniprot id: E4TLZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

643867:FTRAC RS12500
gene id: 643867:FTRAC_RS12500
uniprot id: E4TN65
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS18590
gene id: 643867:FTRAC_RS18590
uniprot id: E4TQJ8
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

643867:FTRAC RS18745
gene id: 643867:FTRAC_RS18745
uniprot id: E4TR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

643867:FTRAC RS08565
gene id: 643867:FTRAC_RS08565
uniprot id: E4TQZ3
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS03735
gene id: 643867:FTRAC_RS03735
uniprot id: E4TRZ5
names: Similarity
messages: Belongs to the Skp family.

643867:FTRAC RS06795
gene id: 643867:FTRAC_RS06795
uniprot id: E4TM72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS13445
gene id: 643867:FTRAC_RS13445
uniprot id: E4TQE3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

643867:FTRAC RS14875
gene id: 643867:FTRAC_RS14875
uniprot id: E4TTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

643867:FTRAC RS07565
gene id: 643867:FTRAC_RS07565
uniprot id: E4TNR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643867:FTRAC RS15265
gene id: 643867:FTRAC_RS15265
uniprot id: E4TU05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

643867:FTRAC RS10990
gene id: 643867:FTRAC_RS10990
uniprot id: E4TVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

643867:FTRAC RS02325
gene id: 643867:FTRAC_RS02325
uniprot id: E4TP66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

643867:FTRAC RS02035
gene id: 643867:FTRAC_RS02035
uniprot id: E4TNF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

643867:FTRAC RS02725
gene id: 643867:FTRAC_RS02725
uniprot id: E4TPZ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS10925
gene id: 643867:FTRAC_RS10925
uniprot id: E4TVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS07585
gene id: 643867:FTRAC_RS07585
uniprot id: E4TNR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

643867:FTRAC RS09710
gene id: 643867:FTRAC_RS09710
uniprot id: E4TT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

643867:FTRAC RS11135
gene id: 643867:FTRAC_RS11135
uniprot id: E4TVW1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643867:FTRAC RS11760
gene id: 643867:FTRAC_RS11760
uniprot id: E4TLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

643867:FTRAC RS04340
gene id: 643867:FTRAC_RS04340
uniprot id: E4TT15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

643867:FTRAC RS16095
gene id: 643867:FTRAC_RS16095
uniprot id: E4TVC9
names: Similarity
messages: Belongs to the universal stress protein A family.

643867:FTRAC RS07145
gene id: 643867:FTRAC_RS07145
uniprot id: E4TMY6
names: Similarity
messages: Belongs to the RelE toxin family.

643867:FTRAC RS15260
gene id: 643867:FTRAC_RS15260
uniprot id: E4TU04
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

643867:FTRAC RS03695
gene id: 643867:FTRAC_RS03695
uniprot id: E4TRY6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

643867:FTRAC RS00380
gene id: 643867:FTRAC_RS00380
uniprot id: E4TVF5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

643867:FTRAC RS01785
gene id: 643867:FTRAC_RS01785
uniprot id: E4TMR3
names: Similarity
messages: Belongs to the YjdM family.

643867:FTRAC RS10255
gene id: 643867:FTRAC_RS10255
uniprot id: E4TUB5
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04645
gene id: 643867:FTRAC_RS04645
uniprot id: E4TTK8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

643867:FTRAC RS15995
gene id: 643867:FTRAC_RS15995
uniprot id: E4TVA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

643867:FTRAC RS08675
gene id: 643867:FTRAC_RS08675
uniprot id: E4TRJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

643867:FTRAC RS14840
gene id: 643867:FTRAC_RS14840
uniprot id: E4TTE3
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS12995
gene id: 643867:FTRAC_RS12995
uniprot id: E4TPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

643867:FTRAC RS13230
gene id: 643867:FTRAC_RS13230
uniprot id: E4TQA2
names: Similarity
messages: Belongs to the group II decarboxylase family.

643867:FTRAC RS11155
gene id: 643867:FTRAC_RS11155
uniprot id: E4TVW5
names: Similarity
messages: Belongs to the RutC family.

643867:FTRAC RS03780
gene id: 643867:FTRAC_RS03780
uniprot id: E4TS04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

643867:FTRAC RS06100
gene id: 643867:FTRAC_RS06100
uniprot id: E4TKN9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS00805
gene id: 643867:FTRAC_RS00805
uniprot id: E4TKI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

643867:FTRAC RS04410
gene id: 643867:FTRAC_RS04410
uniprot id: E4TT29
names: Similarity
messages: Belongs to the citrate synthase family.

643867:FTRAC RS13190
gene id: 643867:FTRAC_RS13190
uniprot id: E4TQ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS11395
gene id: 643867:FTRAC_RS11395
uniprot id: E4TKV7
names: Similarity
messages: Belongs to the asparagine synthetase family.

643867:FTRAC RS16945
gene id: 643867:FTRAC_RS16945
uniprot id: E4TLT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell inner membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

643867:FTRAC RS04010
gene id: 643867:FTRAC_RS04010
uniprot id: E4TSI2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

643867:FTRAC RS15485
gene id: 643867:FTRAC_RS15485
uniprot id: E4TUH8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

643867:FTRAC RS18760
gene id: 643867:FTRAC_RS18760
uniprot id: E4TR74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643867:FTRAC RS16225
gene id: 643867:FTRAC_RS16225
uniprot id: E4TW02
names: Similarity
messages: Belongs to the fabD family.

643867:FTRAC RS04350
gene id: 643867:FTRAC_RS04350
uniprot id: E4TT17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

643867:FTRAC RS10795
gene id: 643867:FTRAC_RS10795
uniprot id: E4TV50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

643867:FTRAC RS16935
gene id: 643867:FTRAC_RS16935
uniprot id: E4TLT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643867:FTRAC RS06160
gene id: 643867:FTRAC_RS06160
uniprot id: E4TKQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS14410
gene id: 643867:FTRAC_RS14410
uniprot id: E4TSE4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS03845
gene id: 643867:FTRAC_RS03845
uniprot id: E4TS17
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

643867:FTRAC RS18000
gene id: 643867:FTRAC_RS18000
uniprot id: E4TP38
names: Similarity
messages: Belongs to the arginase family.

643867:FTRAC RS18450
gene id: 643867:FTRAC_RS18450
uniprot id: E4TQG9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

643867:FTRAC RS00510
gene id: 643867:FTRAC_RS00510
uniprot id: E4TVI0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04275
gene id: 643867:FTRAC_RS04275
uniprot id: E4TT03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

643867:FTRAC RS03525
gene id: 643867:FTRAC_RS03525
uniprot id: E4TRH0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

643867:FTRAC RS07945
gene id: 643867:FTRAC_RS07945
uniprot id: E4TQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

643867:FTRAC RS13215
gene id: 643867:FTRAC_RS13215
uniprot id: E4TQ99
names: Similarity
messages: Belongs to the universal stress protein A family.

643867:FTRAC RS13000
gene id: 643867:FTRAC_RS13000
uniprot id: E4TPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

643867:FTRAC RS18495
gene id: 643867:FTRAC_RS18495
uniprot id: E4TQH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS18575
gene id: 643867:FTRAC_RS18575
uniprot id: E4TQJ5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643867:FTRAC RS05695
gene id: 643867:FTRAC_RS05695
uniprot id: E4TVL6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

643867:FTRAC RS15610
gene id: 643867:FTRAC_RS15610
uniprot id: E4TUK3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS15105
gene id: 643867:FTRAC_RS15105
uniprot id: E4TTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

643867:FTRAC RS12670
gene id: 643867:FTRAC_RS12670
uniprot id: E4TNU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

643867:FTRAC RS08365
gene id: 643867:FTRAC_RS08365
uniprot id: E4TQW0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04155
gene id: 643867:FTRAC_RS04155
uniprot id: E4TSK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

643867:FTRAC RS00275
gene id: 643867:FTRAC_RS00275
uniprot id: E4TVE0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS13675
gene id: 643867:FTRAC_RS13675
uniprot id: E4TR33
names: Similarity
messages: Belongs to the cytochrome c-552 family.

643867:FTRAC RS03715
gene id: 643867:FTRAC_RS03715
uniprot id: E4TRZ0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS11860
gene id: 643867:FTRAC_RS11860
uniprot id: E4TLP7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

643867:FTRAC RS07210
gene id: 643867:FTRAC_RS07210
uniprot id: E4TMZ9
names: Similarity
messages: Belongs to the RecJ family.

643867:FTRAC RS15250
gene id: 643867:FTRAC_RS15250
uniprot id: E4TU02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

643867:FTRAC RS05295
gene id: 643867:FTRAC_RS05295
uniprot id: E4TUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

643867:FTRAC RS11000
gene id: 643867:FTRAC_RS11000
uniprot id: E4TVT6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

643867:FTRAC RS05490
gene id: 643867:FTRAC_RS05490
uniprot id: E4TUY3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS05765
gene id: 643867:FTRAC_RS05765
uniprot id: E4TVN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

643867:FTRAC RS09380
gene id: 643867:FTRAC_RS09380
uniprot id: E4TSP6
names: Similarity
messages: Belongs to the LOG family.

643867:FTRAC RS12445
gene id: 643867:FTRAC_RS12445
uniprot id: E4TN54
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

643867:FTRAC RS16655
gene id: 643867:FTRAC_RS16655
uniprot id: E4TL29
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

643867:FTRAC RS10715
gene id: 643867:FTRAC_RS10715
uniprot id: E4TV33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

643867:FTRAC RS13715
gene id: 643867:FTRAC_RS13715
uniprot id: E4TR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

643867:FTRAC RS11775
gene id: 643867:FTRAC_RS11775
uniprot id: E4TLN0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

643867:FTRAC RS00885
gene id: 643867:FTRAC_RS00885
uniprot id: E4TKK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643867:FTRAC RS05885
gene id: 643867:FTRAC_RS05885
uniprot id: E4TVQ4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

643867:FTRAC RS07325
gene id: 643867:FTRAC_RS07325
uniprot id: E4TNL6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

643867:FTRAC RS15445
gene id: 643867:FTRAC_RS15445
uniprot id: E4TU41
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

643867:FTRAC RS01665
gene id: 643867:FTRAC_RS01665
uniprot id: E4TMP2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS13115
gene id: 643867:FTRAC_RS13115
uniprot id: E4TPN8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

643867:FTRAC RS13065
gene id: 643867:FTRAC_RS13065
uniprot id: E4TPM8
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS07335
gene id: 643867:FTRAC_RS07335
uniprot id: E4TNL8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

643867:FTRAC RS14310
gene id: 643867:FTRAC_RS14310
uniprot id: E4TSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

643867:FTRAC RS15755
gene id: 643867:FTRAC_RS15755
uniprot id: E4TUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

643867:FTRAC RS08125
gene id: 643867:FTRAC_RS08125
uniprot id: E4TQ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

643867:FTRAC RS00760
gene id: 643867:FTRAC_RS00760
uniprot id: E4TKH9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

643867:FTRAC RS07920
gene id: 643867:FTRAC_RS07920
uniprot id: E4TPI2
names: Function
messages: Might have a role analogous to that of eukaryotic histone proteins.

643867:FTRAC RS05060
gene id: 643867:FTRAC_RS05060
uniprot id: E4TU75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

643867:FTRAC RS17245
gene id: 643867:FTRAC_RS17245
uniprot id: E4TMJ2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

643867:FTRAC RS07500
gene id: 643867:FTRAC_RS07500
uniprot id: E4TNQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

643867:FTRAC RS10240
gene id: 643867:FTRAC_RS10240
uniprot id: E4TTX5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643867:FTRAC RS10100
gene id: 643867:FTRAC_RS10100
uniprot id: E4TTU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

643867:FTRAC RS04705
gene id: 643867:FTRAC_RS04705
uniprot id: E4TTM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Cell wall formation.
messages: Cytoplasm

643867:FTRAC RS08095
gene id: 643867:FTRAC_RS08095
uniprot id: E4TQ59
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

643867:FTRAC RS13485
gene id: 643867:FTRAC_RS13485
uniprot id: E4TQF1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643867:FTRAC RS00410
gene id: 643867:FTRAC_RS00410
uniprot id: E4TVG1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

643867:FTRAC RS01540
gene id: 643867:FTRAC_RS01540
uniprot id: E4TM24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

643867:FTRAC RS04735
gene id: 643867:FTRAC_RS04735
uniprot id: E4TTM5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

643867:FTRAC RS12230
gene id: 643867:FTRAC_RS12230
uniprot id: E4TN10
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643867:FTRAC RS03930
gene id: 643867:FTRAC_RS03930
uniprot id: E4TSG6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS04565
gene id: 643867:FTRAC_RS04565
uniprot id: E4TT60
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

643867:FTRAC RS05435
gene id: 643867:FTRAC_RS05435
uniprot id: E4TUX2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

643867:FTRAC RS16090
gene id: 643867:FTRAC_RS16090
uniprot id: E4TVC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

643867:FTRAC RS01995
gene id: 643867:FTRAC_RS01995
uniprot id: E4TNE6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS08835
gene id: 643867:FTRAC_RS08835
uniprot id: E4TRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

643867:FTRAC RS16190
gene id: 643867:FTRAC_RS16190
uniprot id: E4TVZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

643867:FTRAC RS00035
gene id: 643867:FTRAC_RS00035
uniprot id: E4TUP5
names: Similarity
messages: Belongs to the peptidase S41A family.

643867:FTRAC RS06110
gene id: 643867:FTRAC_RS06110
uniprot id: E4TKP1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS02770
gene id: 643867:FTRAC_RS02770
uniprot id: E4TQ00
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

643867:FTRAC RS12240
gene id: 643867:FTRAC_RS12240
uniprot id: E4TN12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

643867:FTRAC RS03585
gene id: 643867:FTRAC_RS03585
uniprot id: E4TRW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

643867:FTRAC RS13345
gene id: 643867:FTRAC_RS13345
uniprot id: E4TQC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

643867:FTRAC RS06810
gene id: 643867:FTRAC_RS06810
uniprot id: E4TM75
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

643867:FTRAC RS05580
gene id: 643867:FTRAC_RS05580
uniprot id: E4TV01
names: Similarity
messages: Belongs to the YciI family.

643867:FTRAC RS00310
gene id: 643867:FTRAC_RS00310
uniprot id: E4TVE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643867:FTRAC RS10615
gene id: 643867:FTRAC_RS10615
uniprot id: E4TV12
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

643867:FTRAC RS18735
gene id: 643867:FTRAC_RS18735
uniprot id: E4TR69
names: Similarity
messages: Belongs to the ParB family.

643867:FTRAC RS13880
gene id: 643867:FTRAC_RS13880
uniprot id: E4TRQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

643867:FTRAC RS11055
gene id: 643867:FTRAC_RS11055
uniprot id: E4TVU6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643867:FTRAC RS07710
gene id: 643867:FTRAC_RS07710
uniprot id: E4TPE1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS09985
gene id: 643867:FTRAC_RS09985
uniprot id: E4TTS2
names: Similarity
messages: Belongs to the group II decarboxylase family.

643867:FTRAC RS14030
gene id: 643867:FTRAC_RS14030
uniprot id: E4TRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS15975
gene id: 643867:FTRAC_RS15975
uniprot id: E4TVA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

643867:FTRAC RS06695
gene id: 643867:FTRAC_RS06695
uniprot id: E4TM52
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS11965
gene id: 643867:FTRAC_RS11965
uniprot id: E4TMB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS16670
gene id: 643867:FTRAC_RS16670
uniprot id: E4TL32
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

643867:FTRAC RS17310
gene id: 643867:FTRAC_RS17310
uniprot id: E4TMK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

643867:FTRAC RS10895
gene id: 643867:FTRAC_RS10895
uniprot id: E4TVR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

643867:FTRAC RS04635
gene id: 643867:FTRAC_RS04635
uniprot id: E4TTK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643867:FTRAC RS09130
gene id: 643867:FTRAC_RS09130
uniprot id: E4TS66
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

643867:FTRAC RS00480
gene id: 643867:FTRAC_RS00480
uniprot id: E4TVH4
names: Subcellular Location Annotation
messages: Cytoplasm

643867:FTRAC RS09715
gene id: 643867:FTRAC_RS09715
uniprot id: E4TT93
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643867:FTRAC RS01095
gene id: 643867:FTRAC_RS01095
uniprot id: E4TL87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

643867:FTRAC RS13650
gene id: 643867:FTRAC_RS13650
uniprot id: E4TR27
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS09270
gene id: 643867:FTRAC_RS09270
uniprot id: E4TSM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS18605
gene id: 643867:FTRAC_RS18605
uniprot id: E4TQK1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS08285
gene id: 643867:FTRAC_RS08285
uniprot id: E4TQU4
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

643867:FTRAC RS05325
gene id: 643867:FTRAC_RS05325
uniprot id: E4TUV1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS02550
gene id: 643867:FTRAC_RS02550
uniprot id: E4TPA9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

643867:FTRAC RS17585
gene id: 643867:FTRAC_RS17585
uniprot id: E4TNA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS04435
gene id: 643867:FTRAC_RS04435
uniprot id: E4TT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS04825
gene id: 643867:FTRAC_RS04825
uniprot id: E4TTP3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

643867:FTRAC RS17620
gene id: 643867:FTRAC_RS17620
uniprot id: E4TNA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

643867:FTRAC RS06760
gene id: 643867:FTRAC_RS06760
uniprot id: E4TM65
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS12090
gene id: 643867:FTRAC_RS12090
uniprot id: E4TMD8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

643867:FTRAC RS00185
gene id: 643867:FTRAC_RS00185
uniprot id: E4TUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS15125
gene id: 643867:FTRAC_RS15125
uniprot id: E4TTX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

643867:FTRAC RS02625
gene id: 643867:FTRAC_RS02625
uniprot id: E4TPX1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

643867:FTRAC RS03210
gene id: 643867:FTRAC_RS03210
uniprot id: E4TQT0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS10195
gene id: 643867:FTRAC_RS10195
uniprot id: E4TTW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS14925
gene id: 643867:FTRAC_RS14925
uniprot id: E4TTG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

643867:FTRAC RS06860
gene id: 643867:FTRAC_RS06860
uniprot id: E4TM85
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

643867:FTRAC RS13480
gene id: 643867:FTRAC_RS13480
uniprot id: E4TQF0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS01560
gene id: 643867:FTRAC_RS01560
uniprot id: E4TM28
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS07790
gene id: 643867:FTRAC_RS07790
uniprot id: E4TPF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

643867:FTRAC RS13955
gene id: 643867:FTRAC_RS13955
uniprot id: E4TRS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

643867:FTRAC RS04585
gene id: 643867:FTRAC_RS04585
uniprot id: E4TTJ6
names: Similarity
messages: Belongs to the SufE family.

643867:FTRAC RS16400
gene id: 643867:FTRAC_RS16400
uniprot id: E4TW37
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

643867:FTRAC RS12580
gene id: 643867:FTRAC_RS12580
uniprot id: E4TNT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643867:FTRAC RS10860
gene id: 643867:FTRAC_RS10860
uniprot id: E4TV64
names: Similarity
messages: Belongs to the Dps family.

643867:FTRAC RS06670
gene id: 643867:FTRAC_RS06670
uniprot id: E4TM47
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

643867:FTRAC RS00400
gene id: 643867:FTRAC_RS00400
uniprot id: E4TVF9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

643867:FTRAC RS09150
gene id: 643867:FTRAC_RS09150
uniprot id: E4TS70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

643867:FTRAC RS09960
gene id: 643867:FTRAC_RS09960
uniprot id: E4TTR7
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16045
gene id: 643867:FTRAC_RS16045
uniprot id: E4TVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

643867:FTRAC RS08450
gene id: 643867:FTRAC_RS08450
uniprot id: E4TQX2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643867:FTRAC RS12235
gene id: 643867:FTRAC_RS12235
uniprot id: E4TN11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

643867:FTRAC RS17745
gene id: 643867:FTRAC_RS17745
uniprot id: E4TNY7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

643867:FTRAC RS07855
gene id: 643867:FTRAC_RS07855
uniprot id: E4TPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

643867:FTRAC RS01645
gene id: 643867:FTRAC_RS01645
uniprot id: E4TMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

643867:FTRAC RS16255
gene id: 643867:FTRAC_RS16255
uniprot id: E4TW08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

643867:FTRAC RS10915
gene id: 643867:FTRAC_RS10915
uniprot id: E4TVR9
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS10595
gene id: 643867:FTRAC_RS10595
uniprot id: E4TV07
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

643867:FTRAC RS03705
gene id: 643867:FTRAC_RS03705
uniprot id: E4TRY8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

643867:FTRAC RS05995
gene id: 643867:FTRAC_RS05995
uniprot id: E4TKM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS00850
gene id: 643867:FTRAC_RS00850
uniprot id: E4TKJ7
names: Similarity
messages: Belongs to the universal stress protein A family.

643867:FTRAC RS16150
gene id: 643867:FTRAC_RS16150
uniprot id: E4TVY7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643867:FTRAC RS00860
gene id: 643867:FTRAC_RS00860
uniprot id: E4TKJ9
names: Similarity
messages: Belongs to the SUI1 family.

643867:FTRAC RS16545
gene id: 643867:FTRAC_RS16545
uniprot id: E4TL07
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

643867:FTRAC RS13370
gene id: 643867:FTRAC_RS13370
uniprot id: E4TQC9
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

643867:FTRAC RS04180
gene id: 643867:FTRAC_RS04180
uniprot id: E4TSL2
names: Subcellular Location Annotation
messages: Cell inner membrane

643867:FTRAC RS01985
gene id: 643867:FTRAC_RS01985
uniprot id: E4TNE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

643867:FTRAC RS15245
gene id: 643867:FTRAC_RS15245
uniprot id: E4TU01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

643867:FTRAC RS00040
gene id: 643867:FTRAC_RS00040
uniprot id: E4TUP6
names: Subcellular Location Annotation
messages: Cytoplasm

643867:FTRAC RS16565
gene id: 643867:FTRAC_RS16565
uniprot id: E4TL11
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

643867:FTRAC RS02500
gene id: 643867:FTRAC_RS02500
uniprot id: E4TPA1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

643867:FTRAC RS17995
gene id: 643867:FTRAC_RS17995
uniprot id: E4TP37
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

643867:FTRAC RS01615
gene id: 643867:FTRAC_RS01615
uniprot id: E4TMN2
names: Similarity
messages: Belongs to the CvfB family.

643867:FTRAC RS04885
gene id: 643867:FTRAC_RS04885
uniprot id: E4TTQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643867:FTRAC RS16650
gene id: 643867:FTRAC_RS16650
uniprot id: E4TL28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

643867:FTRAC RS06820
gene id: 643867:FTRAC_RS06820
uniprot id: E4TM77
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS03925
gene id: 643867:FTRAC_RS03925
uniprot id: E4TSG5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

643867:FTRAC RS04665
gene id: 643867:FTRAC_RS04665
uniprot id: E4TTL2
names: Similarity
messages: Belongs to the XseB family.

643867:FTRAC RS02465
gene id: 643867:FTRAC_RS02465
uniprot id: E4TP94
names: Similarity
messages: Belongs to the peptidase U62 family.

643867:FTRAC RS14820
gene id: 643867:FTRAC_RS14820
uniprot id: E4TTD9
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

643867:FTRAC RS10260
gene id: 643867:FTRAC_RS10260
uniprot id: E4TUB6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

643867:FTRAC RS13685
gene id: 643867:FTRAC_RS13685
uniprot id: E4TR35
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS08900
gene id: 643867:FTRAC_RS08900
uniprot id: E4TRN9
names: Similarity
messages: Belongs to the Skp family.

643867:FTRAC RS09305
gene id: 643867:FTRAC_RS09305
uniprot id: E4TSN1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

643867:FTRAC RS01680
gene id: 643867:FTRAC_RS01680
uniprot id: E4TMP5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

643867:FTRAC RS07675
gene id: 643867:FTRAC_RS07675
uniprot id: E4TPD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

643867:FTRAC RS12035
gene id: 643867:FTRAC_RS12035
uniprot id: E4TMC7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643867:FTRAC RS07130
gene id: 643867:FTRAC_RS07130
uniprot id: E4TMY3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

643867:FTRAC RS14270
gene id: 643867:FTRAC_RS14270
uniprot id: E4TSB5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

643867:FTRAC RS15255
gene id: 643867:FTRAC_RS15255
uniprot id: E4TU03
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

643867:FTRAC RS02295
gene id: 643867:FTRAC_RS02295
uniprot id: E4TP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

643867:FTRAC RS07080
gene id: 643867:FTRAC_RS07080
uniprot id: E4TMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

643867:FTRAC RS19220
gene id: 643867:FTRAC_RS19220
uniprot id: E4TM81
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS00205
gene id: 643867:FTRAC_RS00205
uniprot id: E4TUS9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS00640
gene id: 643867:FTRAC_RS00640
uniprot id: E4TKF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643867:FTRAC RS09720
gene id: 643867:FTRAC_RS09720
uniprot id: E4TT94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

643867:FTRAC RS00320
gene id: 643867:FTRAC_RS00320
uniprot id: E4TVE9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

643867:FTRAC RS02560
gene id: 643867:FTRAC_RS02560
uniprot id: E4TPB1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS06480
gene id: 643867:FTRAC_RS06480
uniprot id: E4TLG3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS00830
gene id: 643867:FTRAC_RS00830
uniprot id: E4TKJ3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

643867:FTRAC RS12320
gene id: 643867:FTRAC_RS12320
uniprot id: E4TN28
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS01545
gene id: 643867:FTRAC_RS01545
uniprot id: E4TM25
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS08570
gene id: 643867:FTRAC_RS08570
uniprot id: E4TQZ4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

643867:FTRAC RS02855
gene id: 643867:FTRAC_RS02855
uniprot id: E4TQ17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS02225
gene id: 643867:FTRAC_RS02225
uniprot id: E4TNJ2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

643867:FTRAC RS14895
gene id: 643867:FTRAC_RS14895
uniprot id: E4TTF4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

643867:FTRAC RS09690
gene id: 643867:FTRAC_RS09690
uniprot id: E4TT88
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

643867:FTRAC RS09110
gene id: 643867:FTRAC_RS09110
uniprot id: E4TS62
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

643867:FTRAC RS16700
gene id: 643867:FTRAC_RS16700
uniprot id: E4TL38
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

643867:FTRAC RS13505
gene id: 643867:FTRAC_RS13505
uniprot id: E4TQF5
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

643867:FTRAC RS03330
gene id: 643867:FTRAC_RS03330
uniprot id: E4TRD1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS13235
gene id: 643867:FTRAC_RS13235
uniprot id: E4TQA3
names: Similarity
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

643867:FTRAC RS14255
gene id: 643867:FTRAC_RS14255
uniprot id: E4TSB2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

643867:FTRAC RS16850
gene id: 643867:FTRAC_RS16850
uniprot id: E4TLR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

643867:FTRAC RS12990
gene id: 643867:FTRAC_RS12990
uniprot id: E4TPL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

643867:FTRAC RS16765
gene id: 643867:FTRAC_RS16765
uniprot id: E4TLQ1
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16870
gene id: 643867:FTRAC_RS16870
uniprot id: E4TLS3
names: Similarity
messages: Belongs to the SCO1/2 family.

643867:FTRAC RS02800
gene id: 643867:FTRAC_RS02800
uniprot id: E4TQ06
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

643867:FTRAC RS17115
gene id: 643867:FTRAC_RS17115
uniprot id: E4TMG6
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS18230
gene id: 643867:FTRAC_RS18230
uniprot id: E4TPS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS17345
gene id: 643867:FTRAC_RS17345
uniprot id: E4TML0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

643867:FTRAC RS16805
gene id: 643867:FTRAC_RS16805
uniprot id: E4TLR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

643867:FTRAC RS17815
gene id: 643867:FTRAC_RS17815
uniprot id: E4TP01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

643867:FTRAC RS01135
gene id: 643867:FTRAC_RS01135
uniprot id: E4TL95
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

643867:FTRAC RS05870
gene id: 643867:FTRAC_RS05870
uniprot id: E4TVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

643867:FTRAC RS17015
gene id: 643867:FTRAC_RS17015
uniprot id: E4TLV2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

643867:FTRAC RS03325
gene id: 643867:FTRAC_RS03325
uniprot id: E4TRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

643867:FTRAC RS09115
gene id: 643867:FTRAC_RS09115
uniprot id: E4TS63
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

643867:FTRAC RS16200
gene id: 643867:FTRAC_RS16200
uniprot id: E4TVZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

643867:FTRAC RS05030
gene id: 643867:FTRAC_RS05030
uniprot id: E4TU70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS11165
gene id: 643867:FTRAC_RS11165
uniprot id: E4TVW7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

643867:FTRAC RS03660
gene id: 643867:FTRAC_RS03660
uniprot id: E4TRX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

643867:FTRAC RS02975
gene id: 643867:FTRAC_RS02975
uniprot id: E4TQN3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

643867:FTRAC RS01610
gene id: 643867:FTRAC_RS01610
uniprot id: E4TMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS15710
gene id: 643867:FTRAC_RS15710
uniprot id: E4TUM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

643867:FTRAC RS03280
gene id: 643867:FTRAC_RS03280
uniprot id: E4TRC1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

643867:FTRAC RS14430
gene id: 643867:FTRAC_RS14430
uniprot id: E4TSE7
names: Similarity
messages: Belongs to the SusD family.

643867:FTRAC RS10140
gene id: 643867:FTRAC_RS10140
uniprot id: E4TTV5
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04545
gene id: 643867:FTRAC_RS04545
uniprot id: E4TT56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

643867:FTRAC RS16040
gene id: 643867:FTRAC_RS16040
uniprot id: E4TVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

643867:FTRAC RS08960
gene id: 643867:FTRAC_RS08960
uniprot id: E4TS32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS03670
gene id: 643867:FTRAC_RS03670
uniprot id: E4TRY1
names: Similarity
messages: Belongs to the SusD family.

643867:FTRAC RS12925
gene id: 643867:FTRAC_RS12925
uniprot id: E4TPK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

643867:FTRAC RS08660
gene id: 643867:FTRAC_RS08660
uniprot id: E4TRJ0
names: Similarity
messages: Belongs to the CarB family.

643867:FTRAC RS04730
gene id: 643867:FTRAC_RS04730
uniprot id: E4TTM4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

643867:FTRAC RS16465
gene id: 643867:FTRAC_RS16465
uniprot id: E4TKZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

643867:FTRAC RS09390
gene id: 643867:FTRAC_RS09390
uniprot id: E4TSP8
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

643867:FTRAC RS11890
gene id: 643867:FTRAC_RS11890
uniprot id: E4TM98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

643867:FTRAC RS00845
gene id: 643867:FTRAC_RS00845
uniprot id: E4TKJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

643867:FTRAC RS00725
gene id: 643867:FTRAC_RS00725
uniprot id: E4TKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

643867:FTRAC RS07770
gene id: 643867:FTRAC_RS07770
uniprot id: E4TPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

643867:FTRAC RS18565
gene id: 643867:FTRAC_RS18565
uniprot id: E4TQJ3
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

643867:FTRAC RS13595
gene id: 643867:FTRAC_RS13595
uniprot id: E4TR16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS12575
gene id: 643867:FTRAC_RS12575
uniprot id: E4TNT0
names: Similarity
messages: Belongs to the DinB family.

643867:FTRAC RS14370
gene id: 643867:FTRAC_RS14370
uniprot id: E4TSD6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS09620
gene id: 643867:FTRAC_RS09620
uniprot id: E4TT75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

643867:FTRAC RS08230
gene id: 643867:FTRAC_RS08230
uniprot id: E4TQ88
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

643867:FTRAC RS01590
gene id: 643867:FTRAC_RS01590
uniprot id: E4TMM7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

643867:FTRAC RS15165
gene id: 643867:FTRAC_RS15165
uniprot id: E4TTY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

643867:FTRAC RS15605
gene id: 643867:FTRAC_RS15605
uniprot id: E4TUK2
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS15150
gene id: 643867:FTRAC_RS15150
uniprot id: E4TTY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

643867:FTRAC RS16810
gene id: 643867:FTRAC_RS16810
uniprot id: E4TLR1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

643867:FTRAC RS16495
gene id: 643867:FTRAC_RS16495
uniprot id: E4TKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS10800
gene id: 643867:FTRAC_RS10800
uniprot id: E4TV51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643867:FTRAC RS16895
gene id: 643867:FTRAC_RS16895
uniprot id: E4TLS8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

643867:FTRAC RS13080
gene id: 643867:FTRAC_RS13080
uniprot id: E4TPN1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

643867:FTRAC RS04060
gene id: 643867:FTRAC_RS04060
uniprot id: E4TSI9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

643867:FTRAC RS13325
gene id: 643867:FTRAC_RS13325
uniprot id: E4TQC1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

643867:FTRAC RS10325
gene id: 643867:FTRAC_RS10325
uniprot id: E4TUD0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS00230
gene id: 643867:FTRAC_RS00230
uniprot id: E4TUT4
names: Similarity
messages: Belongs to the pirin family.

643867:FTRAC RS18075
gene id: 643867:FTRAC_RS18075
uniprot id: E4TP52
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS18465
gene id: 643867:FTRAC_RS18465
uniprot id: E4TQH2
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04440
gene id: 643867:FTRAC_RS04440
uniprot id: E4TT35
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS11750
gene id: 643867:FTRAC_RS11750
uniprot id: E4TLM5
names: Similarity
messages: Belongs to the peptidase M16 family.

643867:FTRAC RS08405
gene id: 643867:FTRAC_RS08405
uniprot id: E4TQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS16725
gene id: 643867:FTRAC_RS16725
uniprot id: E4TL43
names: Similarity
messages: Belongs to the GARS family.

643867:FTRAC RS05720
gene id: 643867:FTRAC_RS05720
uniprot id: E4TVM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

643867:FTRAC RS10025
gene id: 643867:FTRAC_RS10025
uniprot id: E4TTT1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

643867:FTRAC RS04290
gene id: 643867:FTRAC_RS04290
uniprot id: E4TT06
names: Similarity
messages: Belongs to the glutamate synthase family.

643867:FTRAC RS08180
gene id: 643867:FTRAC_RS08180
uniprot id: E4TQ76
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS00690
gene id: 643867:FTRAC_RS00690
uniprot id: E4TKG4
names: Similarity
messages: Belongs to the SusD family.

643867:FTRAC RS14105
gene id: 643867:FTRAC_RS14105
uniprot id: E4TRV0
names: Similarity
messages: Belongs to the arginase family.

643867:FTRAC RS07670
gene id: 643867:FTRAC_RS07670
uniprot id: E4TPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

643867:FTRAC RS16480
gene id: 643867:FTRAC_RS16480
uniprot id: E4TKZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

643867:FTRAC RS18025
gene id: 643867:FTRAC_RS18025
uniprot id: E4TP43
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643867:FTRAC RS16685
gene id: 643867:FTRAC_RS16685
uniprot id: E4TL35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

643867:FTRAC RS07775
gene id: 643867:FTRAC_RS07775
uniprot id: E4TPF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

643867:FTRAC RS07510
gene id: 643867:FTRAC_RS07510
uniprot id: E4TNQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS16010
gene id: 643867:FTRAC_RS16010
uniprot id: E4TVB1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

643867:FTRAC RS08885
gene id: 643867:FTRAC_RS08885
uniprot id: E4TRN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

643867:FTRAC RS07625
gene id: 643867:FTRAC_RS07625
uniprot id: E4TPC4
names: Similarity
messages: Belongs to the peptidase S8 family.

643867:FTRAC RS01575
gene id: 643867:FTRAC_RS01575
uniprot id: E4TMM4
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS13815
gene id: 643867:FTRAC_RS13815
uniprot id: E4TR60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

643867:FTRAC RS18115
gene id: 643867:FTRAC_RS18115
uniprot id: E4TPQ7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

643867:FTRAC RS08320
gene id: 643867:FTRAC_RS08320
uniprot id: E4TQV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643867:FTRAC RS14170
gene id: 643867:FTRAC_RS14170
uniprot id: E4TS96
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS00340
gene id: 643867:FTRAC_RS00340
uniprot id: E4TVF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

643867:FTRAC RS02845
gene id: 643867:FTRAC_RS02845
uniprot id: E4TQ15
names: Cofactor
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS12430
gene id: 643867:FTRAC_RS12430
uniprot id: E4TN51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

643867:FTRAC RS15565
gene id: 643867:FTRAC_RS15565
uniprot id: E4TUJ4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

643867:FTRAC RS16950
gene id: 643867:FTRAC_RS16950
uniprot id: E4TLT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

643867:FTRAC RS10055
gene id: 643867:FTRAC_RS10055
uniprot id: E4TTT7
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS04800
gene id: 643867:FTRAC_RS04800
uniprot id: E4TTN8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

643867:FTRAC RS19325
gene id: 643867:FTRAC_RS19325
uniprot id: E4TLP1
names: Similarity
messages: Belongs to the peptidase S33 family.

643867:FTRAC RS15295
gene id: 643867:FTRAC_RS15295
uniprot id: E4TU12
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

643867:FTRAC RS03915
gene id: 643867:FTRAC_RS03915
uniprot id: E4TSG3
names: Similarity
messages: Belongs to the ribF family.

643867:FTRAC RS09705
gene id: 643867:FTRAC_RS09705
uniprot id: E4TT91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

643867:FTRAC RS13525
gene id: 643867:FTRAC_RS13525
uniprot id: E4TR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS17380
gene id: 643867:FTRAC_RS17380
uniprot id: E4TML7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

643867:FTRAC RS02350
gene id: 643867:FTRAC_RS02350
uniprot id: E4TP71
names: Similarity
messages: Belongs to the glutathione peroxidase family.

643867:FTRAC RS09905
gene id: 643867:FTRAC_RS09905
uniprot id: E4TTD1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

643867:FTRAC RS16175
gene id: 643867:FTRAC_RS16175
uniprot id: E4TVZ2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

643867:FTRAC RS18795
gene id: 643867:FTRAC_RS18795
uniprot id: E4TR81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

643867:FTRAC RS15175
gene id: 643867:FTRAC_RS15175
uniprot id: E4TTY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

643867:FTRAC RS01195
gene id: 643867:FTRAC_RS01195
uniprot id: E4TLA6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

643867:FTRAC RS12465
gene id: 643867:FTRAC_RS12465
uniprot id: E4TN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

643867:FTRAC RS03985
gene id: 643867:FTRAC_RS03985
uniprot id: E4TSH7
names: Similarity
messages: Belongs to the UPF0102 family.

643867:FTRAC RS17765
gene id: 643867:FTRAC_RS17765
uniprot id: E4TNZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

643867:FTRAC RS06115
gene id: 643867:FTRAC_RS06115
uniprot id: E4TKP2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS15965
gene id: 643867:FTRAC_RS15965
uniprot id: E4TVA2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

643867:FTRAC RS13270
gene id: 643867:FTRAC_RS13270
uniprot id: E4TQB0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16180
gene id: 643867:FTRAC_RS16180
uniprot id: E4TVZ3
names: Similarity
messages: Belongs to the peptidase S33 family.

643867:FTRAC RS07305
gene id: 643867:FTRAC_RS07305
uniprot id: E4TNL2
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS07290
gene id: 643867:FTRAC_RS07290
uniprot id: E4TNK9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS14295
gene id: 643867:FTRAC_RS14295
uniprot id: E4TSC0
names: Subcellular Location Annotation
messages: extracellular matrix

643867:FTRAC RS10155
gene id: 643867:FTRAC_RS10155
uniprot id: E4TTV8
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS09065
gene id: 643867:FTRAC_RS09065
uniprot id: E4TS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS13180
gene id: 643867:FTRAC_RS13180
uniprot id: E4TQ92
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS06020
gene id: 643867:FTRAC_RS06020
uniprot id: E4TKM8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

643867:FTRAC RS06445
gene id: 643867:FTRAC_RS06445
uniprot id: E4TLF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS00280
gene id: 643867:FTRAC_RS00280
uniprot id: E4TVE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

643867:FTRAC RS18855
gene id: 643867:FTRAC_RS18855
uniprot id: E4TR93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

643867:FTRAC RS12025
gene id: 643867:FTRAC_RS12025
uniprot id: E4TMC5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

643867:FTRAC RS07680
gene id: 643867:FTRAC_RS07680
uniprot id: E4TPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

643867:FTRAC RS16695
gene id: 643867:FTRAC_RS16695
uniprot id: E4TL37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

643867:FTRAC RS12100
gene id: 643867:FTRAC_RS12100
uniprot id: E4TME0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

643867:FTRAC RS04790
gene id: 643867:FTRAC_RS04790
uniprot id: E4TTN6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643867:FTRAC RS08645
gene id: 643867:FTRAC_RS08645
uniprot id: E4TRI7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643867:FTRAC RS12050
gene id: 643867:FTRAC_RS12050
uniprot id: E4TMD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

643867:FTRAC RS13130
gene id: 643867:FTRAC_RS13130
uniprot id: E4TPP1
names: Similarity
messages: Belongs to the SusD family.

643867:FTRAC RS04660
gene id: 643867:FTRAC_RS04660
uniprot id: E4TTL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

643867:FTRAC RS08085
gene id: 643867:FTRAC_RS08085
uniprot id: E4TQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643867:FTRAC RS00170
gene id: 643867:FTRAC_RS00170
uniprot id: E4TUS2
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

643867:FTRAC RS03800
gene id: 643867:FTRAC_RS03800
uniprot id: E4TS08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

643867:FTRAC RS09435
gene id: 643867:FTRAC_RS09435
uniprot id: E4TSQ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643867:FTRAC RS06025
gene id: 643867:FTRAC_RS06025
uniprot id: E4TKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

643867:FTRAC RS13435
gene id: 643867:FTRAC_RS13435
uniprot id: E4TQE1
names: Similarity
messages: Belongs to the NAPRTase family.

643867:FTRAC RS13600
gene id: 643867:FTRAC_RS13600
uniprot id: E4TR17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

643867:FTRAC RS05725
gene id: 643867:FTRAC_RS05725
uniprot id: E4TVM1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS14535
gene id: 643867:FTRAC_RS14535
uniprot id: E4TSU4
names: Similarity
messages: Belongs to the CapA family.

643867:FTRAC RS12625
gene id: 643867:FTRAC_RS12625
uniprot id: E4TNT9
names: Similarity
messages: Belongs to the glutamate synthase family.

643867:FTRAC RS11845
gene id: 643867:FTRAC_RS11845
uniprot id: E4TLP4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

643867:FTRAC RS17385
gene id: 643867:FTRAC_RS17385
uniprot id: E4TML8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

643867:FTRAC RS07430
gene id: 643867:FTRAC_RS07430
uniprot id: E4TNN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

643867:FTRAC RS11700
gene id: 643867:FTRAC_RS11700
uniprot id: E4TLL5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643867:FTRAC RS03490
gene id: 643867:FTRAC_RS03490
uniprot id: E4TRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS03360
gene id: 643867:FTRAC_RS03360
uniprot id: E4TRD8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

643867:FTRAC RS03740
gene id: 643867:FTRAC_RS03740
uniprot id: E4TRZ6
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS13965
gene id: 643867:FTRAC_RS13965
uniprot id: E4TRS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

643867:FTRAC RS14545
gene id: 643867:FTRAC_RS14545
uniprot id: E4TSU6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

643867:FTRAC RS03410
gene id: 643867:FTRAC_RS03410
uniprot id: E4TRE8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

643867:FTRAC RS11260
gene id: 643867:FTRAC_RS11260
uniprot id: E4TKT1
names: Similarity
messages: Belongs to the MreC family.

643867:FTRAC RS09510
gene id: 643867:FTRAC_RS09510
uniprot id: E4TSS3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS15110
gene id: 643867:FTRAC_RS15110
uniprot id: E4TTJ3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

643867:FTRAC RS08515
gene id: 643867:FTRAC_RS08515
uniprot id: E4TQY5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

643867:FTRAC RS13695
gene id: 643867:FTRAC_RS13695
uniprot id: E4TR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS16425
gene id: 643867:FTRAC_RS16425
uniprot id: E4TW42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

643867:FTRAC RS08855
gene id: 643867:FTRAC_RS08855
uniprot id: E4TRM9
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS07280
gene id: 643867:FTRAC_RS07280
uniprot id: E4TNK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

643867:FTRAC RS03090
gene id: 643867:FTRAC_RS03090
uniprot id: E4TQQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643867:FTRAC RS01210
gene id: 643867:FTRAC_RS01210
uniprot id: E4TLA9
names: Similarity
messages: Belongs to the HsdR family.

643867:FTRAC RS20045
gene id: 643867:FTRAC_RS20045
uniprot id: E4TPQ8
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

643867:FTRAC RS03085
gene id: 643867:FTRAC_RS03085
uniprot id: E4TQQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643867:FTRAC RS12220
gene id: 643867:FTRAC_RS12220
uniprot id: E4TN09
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

643867:FTRAC RS15990
gene id: 643867:FTRAC_RS15990
uniprot id: E4TVA7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

643867:FTRAC RS05750
gene id: 643867:FTRAC_RS05750
uniprot id: E4TVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

643867:FTRAC RS16450
gene id: 643867:FTRAC_RS16450
uniprot id: E4TKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

643867:FTRAC RS01800
gene id: 643867:FTRAC_RS01800
uniprot id: E4TMR6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

643867:FTRAC RS14145
gene id: 643867:FTRAC_RS14145
uniprot id: E4TRV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643867:FTRAC RS15680
gene id: 643867:FTRAC_RS15680
uniprot id: E4TUL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS03260
gene id: 643867:FTRAC_RS03260
uniprot id: E4TRB7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

643867:FTRAC RS14225
gene id: 643867:FTRAC_RS14225
uniprot id: E4TSA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS12850
gene id: 643867:FTRAC_RS12850
uniprot id: E4TPI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

643867:FTRAC RS04145
gene id: 643867:FTRAC_RS04145
uniprot id: E4TSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

643867:FTRAC RS15135
gene id: 643867:FTRAC_RS15135
uniprot id: E4TTX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643867:FTRAC RS12170
gene id: 643867:FTRAC_RS12170
uniprot id: E4TMF4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

643867:FTRAC RS14240
gene id: 643867:FTRAC_RS14240
uniprot id: E4TSB0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

643867:FTRAC RS08020
gene id: 643867:FTRAC_RS08020
uniprot id: E4TQ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

643867:FTRAC RS13605
gene id: 643867:FTRAC_RS13605
uniprot id: E4TR18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

643867:FTRAC RS07485
gene id: 643867:FTRAC_RS07485
uniprot id: E4TNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

643867:FTRAC RS01685
gene id: 643867:FTRAC_RS01685
uniprot id: E4TMP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS18850
gene id: 643867:FTRAC_RS18850
uniprot id: E4TR92
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS08415
gene id: 643867:FTRAC_RS08415
uniprot id: E4TQW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

643867:FTRAC RS00420
gene id: 643867:FTRAC_RS00420
uniprot id: E4TVG3
names: Similarity
messages: Belongs to the IMPACT family.

643867:FTRAC RS02490
gene id: 643867:FTRAC_RS02490
uniprot id: E4TP99
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

643867:FTRAC RS16000
gene id: 643867:FTRAC_RS16000
uniprot id: E4TVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

643867:FTRAC RS11270
gene id: 643867:FTRAC_RS11270
uniprot id: E4TKT3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

643867:FTRAC RS00095
gene id: 643867:FTRAC_RS00095
uniprot id: E4TUQ7
names: Similarity
messages: Belongs to the PspA/IM30 family.

643867:FTRAC RS08475
gene id: 643867:FTRAC_RS08475
uniprot id: E4TQX7
names: Similarity
messages: Belongs to the peptidase S51 family.

643867:FTRAC RS13825
gene id: 643867:FTRAC_RS13825
uniprot id: E4TR62
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

643867:FTRAC RS18255
gene id: 643867:FTRAC_RS18255
uniprot id: E4TPT4
names: Similarity
messages: Belongs to the malate synthase family.

643867:FTRAC RS16275
gene id: 643867:FTRAC_RS16275
uniprot id: E4TW12
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

643867:FTRAC RS00815
gene id: 643867:FTRAC_RS00815
uniprot id: E4TKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

643867:FTRAC RS00295
gene id: 643867:FTRAC_RS00295
uniprot id: E4TVE4
names: Similarity
messages: Belongs to the peptidase C40 family.

643867:FTRAC RS08040
gene id: 643867:FTRAC_RS08040
uniprot id: E4TQ49
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

643867:FTRAC RS16035
gene id: 643867:FTRAC_RS16035
uniprot id: E4TVB6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

643867:FTRAC RS09495
gene id: 643867:FTRAC_RS09495
uniprot id: E4TSS0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS18235
gene id: 643867:FTRAC_RS18235
uniprot id: E4TPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS08205
gene id: 643867:FTRAC_RS08205
uniprot id: E4TQ82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS07340
gene id: 643867:FTRAC_RS07340
uniprot id: E4TNL9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS18585
gene id: 643867:FTRAC_RS18585
uniprot id: E4TQJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

643867:FTRAC RS15470
gene id: 643867:FTRAC_RS15470
uniprot id: E4TU46
names: Similarity
messages: Belongs to the UPF0758 family.

643867:FTRAC RS04270
gene id: 643867:FTRAC_RS04270
uniprot id: E4TT02
names: Similarity
messages: Belongs to the ArsC family.

643867:FTRAC RS05095
gene id: 643867:FTRAC_RS05095
uniprot id: E4TU82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS14760
gene id: 643867:FTRAC_RS14760
uniprot id: E4TSY8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

643867:FTRAC RS01595
gene id: 643867:FTRAC_RS01595
uniprot id: E4TMM8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

643867:FTRAC RS14155
gene id: 643867:FTRAC_RS14155
uniprot id: E4TRW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

643867:FTRAC RS18665
gene id: 643867:FTRAC_RS18665
uniprot id: E4TQL4
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS02780
gene id: 643867:FTRAC_RS02780
uniprot id: E4TQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

643867:FTRAC RS14205
gene id: 643867:FTRAC_RS14205
uniprot id: E4TSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

643867:FTRAC RS15210
gene id: 643867:FTRAC_RS15210
uniprot id: E4TTZ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

643867:FTRAC RS06425
gene id: 643867:FTRAC_RS06425
uniprot id: E4TLF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643867:FTRAC RS00225
gene id: 643867:FTRAC_RS00225
uniprot id: E4TUT3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

643867:FTRAC RS18550
gene id: 643867:FTRAC_RS18550
uniprot id: E4TQJ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643867:FTRAC RS19270
gene id: 643867:FTRAC_RS19270
uniprot id: E4TQW8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS05800
gene id: 643867:FTRAC_RS05800
uniprot id: E4TVN7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

643867:FTRAC RS13175
gene id: 643867:FTRAC_RS13175
uniprot id: E4TPQ0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS15155
gene id: 643867:FTRAC_RS15155
uniprot id: E4TTY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

643867:FTRAC RS07785
gene id: 643867:FTRAC_RS07785
uniprot id: E4TPF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

643867:FTRAC RS00785
gene id: 643867:FTRAC_RS00785
uniprot id: E4TKI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS18310
gene id: 643867:FTRAC_RS18310
uniprot id: E4TPU6
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS05760
gene id: 643867:FTRAC_RS05760
uniprot id: E4TVM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS00440
gene id: 643867:FTRAC_RS00440
uniprot id: E4TVG7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

643867:FTRAC RS01470
gene id: 643867:FTRAC_RS01470
uniprot id: E4TM09
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

643867:FTRAC RS14200
gene id: 643867:FTRAC_RS14200
uniprot id: E4TSA2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

643867:FTRAC RS15465
gene id: 643867:FTRAC_RS15465
uniprot id: E4TU45
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

643867:FTRAC RS15170
gene id: 643867:FTRAC_RS15170
uniprot id: E4TTY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

643867:FTRAC RS08840
gene id: 643867:FTRAC_RS08840
uniprot id: E4TRM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS14450
gene id: 643867:FTRAC_RS14450
uniprot id: E4TSF1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

643867:FTRAC RS11215
gene id: 643867:FTRAC_RS11215
uniprot id: E4TVX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

643867:FTRAC RS11690
gene id: 643867:FTRAC_RS11690
uniprot id: E4TLL3
names: Similarity
messages: Belongs to the glutamate synthase family.

643867:FTRAC RS00745
gene id: 643867:FTRAC_RS00745
uniprot id: E4TKH6
names: Similarity
messages: Belongs to the universal stress protein A family.

643867:FTRAC RS00405
gene id: 643867:FTRAC_RS00405
uniprot id: E4TVG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

643867:FTRAC RS07550
gene id: 643867:FTRAC_RS07550
uniprot id: E4TNR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

643867:FTRAC RS12325
gene id: 643867:FTRAC_RS12325
uniprot id: E4TN29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

643867:FTRAC RS01405
gene id: 643867:FTRAC_RS01405
uniprot id: E4TLZ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

643867:FTRAC RS07460
gene id: 643867:FTRAC_RS07460
uniprot id: E4TNP3
names: Subunit
messages: Homodimer.

643867:FTRAC RS04335
gene id: 643867:FTRAC_RS04335
uniprot id: E4TT14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

643867:FTRAC RS04690
gene id: 643867:FTRAC_RS04690
uniprot id: E4TTL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

643867:FTRAC RS11385
gene id: 643867:FTRAC_RS11385
uniprot id: E4TKV5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643867:FTRAC RS16675
gene id: 643867:FTRAC_RS16675
uniprot id: E4TL33
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

643867:FTRAC RS06975
gene id: 643867:FTRAC_RS06975
uniprot id: E4TMV3
names: Similarity
messages: Belongs to the HsdR family.

643867:FTRAC RS12835
gene id: 643867:FTRAC_RS12835
uniprot id: E4TNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

643867:FTRAC RS08445
gene id: 643867:FTRAC_RS08445
uniprot id: E4TQX1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643867:FTRAC RS16195
gene id: 643867:FTRAC_RS16195
uniprot id: E4TVZ6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

643867:FTRAC RS00810
gene id: 643867:FTRAC_RS00810
uniprot id: E4TKI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

643867:FTRAC RS04150
gene id: 643867:FTRAC_RS04150
uniprot id: E4TSK6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS03885
gene id: 643867:FTRAC_RS03885
uniprot id: E4TS25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS16185
gene id: 643867:FTRAC_RS16185
uniprot id: E4TVZ4
names: Similarity
messages: Belongs to the universal stress protein A family.

643867:FTRAC RS16750
gene id: 643867:FTRAC_RS16750
uniprot id: E4TL50
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643867:FTRAC RS07640
gene id: 643867:FTRAC_RS07640
uniprot id: E4TPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

643867:FTRAC RS04050
gene id: 643867:FTRAC_RS04050
uniprot id: E4TSI7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

643867:FTRAC RS00940
gene id: 643867:FTRAC_RS00940
uniprot id: E4TL55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

643867:FTRAC RS15970
gene id: 643867:FTRAC_RS15970
uniprot id: E4TVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

643867:FTRAC RS17865
gene id: 643867:FTRAC_RS17865
uniprot id: E4TP11
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

643867:FTRAC RS10670
gene id: 643867:FTRAC_RS10670
uniprot id: E4TV24
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

643867:FTRAC RS10490
gene id: 643867:FTRAC_RS10490
uniprot id: E4TUG3
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS12845
gene id: 643867:FTRAC_RS12845
uniprot id: E4TNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

643867:FTRAC RS10780
gene id: 643867:FTRAC_RS10780
uniprot id: E4TV47
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS01000
gene id: 643867:FTRAC_RS01000
uniprot id: E4TL67
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

643867:FTRAC RS01515
gene id: 643867:FTRAC_RS01515
uniprot id: E4TM19
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

643867:FTRAC RS07695
gene id: 643867:FTRAC_RS07695
uniprot id: E4TPD8
names: Similarity
messages: Belongs to the thioredoxin family.

643867:FTRAC RS07315
gene id: 643867:FTRAC_RS07315
uniprot id: E4TNL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

643867:FTRAC RS04425
gene id: 643867:FTRAC_RS04425
uniprot id: E4TT32
names: Subcellular Location Annotation
messages: Cytoplasm

643867:FTRAC RS02655
gene id: 643867:FTRAC_RS02655
uniprot id: E4TPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643867:FTRAC RS16440
gene id: 643867:FTRAC_RS16440
uniprot id: E4TKY6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS03520
gene id: 643867:FTRAC_RS03520
uniprot id: E4TRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643867:FTRAC RS05240
gene id: 643867:FTRAC_RS05240
uniprot id: E4TUB1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS06575
gene id: 643867:FTRAC_RS06575
uniprot id: E4TLI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS18140
gene id: 643867:FTRAC_RS18140
uniprot id: E4TPR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS06165
gene id: 643867:FTRAC_RS06165
uniprot id: E4TKQ2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

643867:FTRAC RS00290
gene id: 643867:FTRAC_RS00290
uniprot id: E4TVE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

643867:FTRAC RS04680
gene id: 643867:FTRAC_RS04680
uniprot id: E4TTL5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

643867:FTRAC RS09455
gene id: 643867:FTRAC_RS09455
uniprot id: E4TSR1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

643867:FTRAC RS14800
gene id: 643867:FTRAC_RS14800
uniprot id: E4TTD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS18045
gene id: 643867:FTRAC_RS18045
uniprot id: E4TP46
names: Similarity
messages: Belongs to the peptidase M24B family.

643867:FTRAC RS11545
gene id: 643867:FTRAC_RS11545
uniprot id: E4TLI5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643867:FTRAC RS04685
gene id: 643867:FTRAC_RS04685
uniprot id: E4TTL6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

643867:FTRAC RS15780
gene id: 643867:FTRAC_RS15780
uniprot id: E4TUN7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS15220
gene id: 643867:FTRAC_RS15220
uniprot id: E4TTZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

643867:FTRAC RS08215
gene id: 643867:FTRAC_RS08215
uniprot id: E4TQ85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS05880
gene id: 643867:FTRAC_RS05880
uniprot id: E4TVQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

643867:FTRAC RS00045
gene id: 643867:FTRAC_RS00045
uniprot id: E4TUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

643867:FTRAC RS18905
gene id: 643867:FTRAC_RS18905
uniprot id: E4TRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS10395
gene id: 643867:FTRAC_RS10395
uniprot id: E4TUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

643867:FTRAC RS04505
gene id: 643867:FTRAC_RS04505
uniprot id: E4TT48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

643867:FTRAC RS11330
gene id: 643867:FTRAC_RS11330
uniprot id: E4TKU4
names: Similarity
messages: Belongs to the DEAD box helicase family.

643867:FTRAC RS10105
gene id: 643867:FTRAC_RS10105
uniprot id: E4TTU7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

643867:FTRAC RS04575
gene id: 643867:FTRAC_RS04575
uniprot id: E4TT63
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

643867:FTRAC RS15290
gene id: 643867:FTRAC_RS15290
uniprot id: E4TU11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

643867:FTRAC RS08950
gene id: 643867:FTRAC_RS08950
uniprot id: E4TS30
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS03635
gene id: 643867:FTRAC_RS03635
uniprot id: E4TRX4
names: Similarity
messages: Belongs to the UPF0246 family.

643867:FTRAC RS14375
gene id: 643867:FTRAC_RS14375
uniprot id: E4TSD7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS06105
gene id: 643867:FTRAC_RS06105
uniprot id: E4TKP0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS13690
gene id: 643867:FTRAC_RS13690
uniprot id: E4TR36
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS12450
gene id: 643867:FTRAC_RS12450
uniprot id: E4TN55
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

643867:FTRAC RS12795
gene id: 643867:FTRAC_RS12795
uniprot id: E4TNX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

643867:FTRAC RS00740
gene id: 643867:FTRAC_RS00740
uniprot id: E4TKH5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

643867:FTRAC RS14015
gene id: 643867:FTRAC_RS14015
uniprot id: E4TRT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS17135
gene id: 643867:FTRAC_RS17135
uniprot id: E4TMH0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS08625
gene id: 643867:FTRAC_RS08625
uniprot id: E4TRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

643867:FTRAC RS09145
gene id: 643867:FTRAC_RS09145
uniprot id: E4TS69
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

643867:FTRAC RS16170
gene id: 643867:FTRAC_RS16170
uniprot id: E4TVZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

643867:FTRAC RS12210
gene id: 643867:FTRAC_RS12210
uniprot id: E4TN07
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

643867:FTRAC RS06920
gene id: 643867:FTRAC_RS06920
uniprot id: E4TMU2
names: Similarity
messages: Belongs to the pirin family.

643867:FTRAC RS12535
gene id: 643867:FTRAC_RS12535
uniprot id: E4TNS2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

643867:FTRAC RS14515
gene id: 643867:FTRAC_RS14515
uniprot id: E4TSU0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS07475
gene id: 643867:FTRAC_RS07475
uniprot id: E4TNP6
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

643867:FTRAC RS13515
gene id: 643867:FTRAC_RS13515
uniprot id: E4TQF7
names: Similarity
messages: Belongs to the SCO1/2 family.

643867:FTRAC RS12005
gene id: 643867:FTRAC_RS12005
uniprot id: E4TMC1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS11365
gene id: 643867:FTRAC_RS11365
uniprot id: E4TKV1
names: Similarity
messages: Belongs to the peptidase C40 family.

643867:FTRAC RS17130
gene id: 643867:FTRAC_RS17130
uniprot id: E4TMG9
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS03700
gene id: 643867:FTRAC_RS03700
uniprot id: E4TRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

643867:FTRAC RS08705
gene id: 643867:FTRAC_RS08705
uniprot id: E4TRJ9
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

643867:FTRAC RS15270
gene id: 643867:FTRAC_RS15270
uniprot id: E4TU06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

643867:FTRAC RS08870
gene id: 643867:FTRAC_RS08870
uniprot id: E4TRN2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643867:FTRAC RS14465
gene id: 643867:FTRAC_RS14465
uniprot id: E4TSF4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS16615
gene id: 643867:FTRAC_RS16615
uniprot id: E4TL21
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643867:FTRAC RS05050
gene id: 643867:FTRAC_RS05050
uniprot id: E4TU73
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

643867:FTRAC RS00790
gene id: 643867:FTRAC_RS00790
uniprot id: E4TKI5
names: Similarity
messages: Belongs to the SusD family.

643867:FTRAC RS10210
gene id: 643867:FTRAC_RS10210
uniprot id: E4TTW9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

643867:FTRAC RS18525
gene id: 643867:FTRAC_RS18525
uniprot id: E4TQI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

643867:FTRAC RS13975
gene id: 643867:FTRAC_RS13975
uniprot id: E4TRS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS00515
gene id: 643867:FTRAC_RS00515
uniprot id: E4TVI1
names: Similarity
messages: Belongs to the ice-binding protein family.

643867:FTRAC RS10330
gene id: 643867:FTRAC_RS10330
uniprot id: E4TUD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643867:FTRAC RS14130
gene id: 643867:FTRAC_RS14130
uniprot id: E4TRV6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

643867:FTRAC RS13220
gene id: 643867:FTRAC_RS13220
uniprot id: E4TQA0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS18755
gene id: 643867:FTRAC_RS18755
uniprot id: E4TR73
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

643867:FTRAC RS07535
gene id: 643867:FTRAC_RS07535
uniprot id: E4TNQ7
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS17680
gene id: 643867:FTRAC_RS17680
uniprot id: E4TNC0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

643867:FTRAC RS11400
gene id: 643867:FTRAC_RS11400
uniprot id: E4TKV8
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS17675
gene id: 643867:FTRAC_RS17675
uniprot id: E4TNB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

643867:FTRAC RS09725
gene id: 643867:FTRAC_RS09725
uniprot id: E4TT95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

643867:FTRAC RS08680
gene id: 643867:FTRAC_RS08680
uniprot id: E4TRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

643867:FTRAC RS15160
gene id: 643867:FTRAC_RS15160
uniprot id: E4TTY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

643867:FTRAC RS08845
gene id: 643867:FTRAC_RS08845
uniprot id: E4TRM7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

643867:FTRAC RS07645
gene id: 643867:FTRAC_RS07645
uniprot id: E4TPC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

643867:FTRAC RS00800
gene id: 643867:FTRAC_RS00800
uniprot id: E4TKI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

643867:FTRAC RS10300
gene id: 643867:FTRAC_RS10300
uniprot id: E4TUC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643867:FTRAC RS12305
gene id: 643867:FTRAC_RS12305
uniprot id: E4TN25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS01235
gene id: 643867:FTRAC_RS01235
uniprot id: E4TLB5
names: Similarity
messages: Belongs to the Skp family.

643867:FTRAC RS17805
gene id: 643867:FTRAC_RS17805
uniprot id: E4TNZ9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS14355
gene id: 643867:FTRAC_RS14355
uniprot id: E4TSD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS09195
gene id: 643867:FTRAC_RS09195
uniprot id: E4TS79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

643867:FTRAC RS08915
gene id: 643867:FTRAC_RS08915
uniprot id: E4TRP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

643867:FTRAC RS01690
gene id: 643867:FTRAC_RS01690
uniprot id: E4TMP7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643867:FTRAC RS04420
gene id: 643867:FTRAC_RS04420
uniprot id: E4TT31
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643867:FTRAC RS01660
gene id: 643867:FTRAC_RS01660
uniprot id: E4TMP1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

643867:FTRAC RS18040
gene id: 643867:FTRAC_RS18040
uniprot id: E4TP45
names: Similarity
messages: Belongs to the peptidase S8 family.

643867:FTRAC RS01475
gene id: 643867:FTRAC_RS01475
uniprot id: E4TM10
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643867:FTRAC RS17735
gene id: 643867:FTRAC_RS17735
uniprot id: E4TNY5
names: Similarity
messages: Belongs to the arginase family.

643867:FTRAC RS05415
gene id: 643867:FTRAC_RS05415
uniprot id: E4TUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

643867:FTRAC RS00010
gene id: 643867:FTRAC_RS00010
uniprot id: E4TUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

643867:FTRAC RS11905
gene id: 643867:FTRAC_RS11905
uniprot id: E4TMA1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

643867:FTRAC RS09730
gene id: 643867:FTRAC_RS09730
uniprot id: E4TT96
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

643867:FTRAC RS12710
gene id: 643867:FTRAC_RS12710
uniprot id: E4TNV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

643867:FTRAC RS13570
gene id: 643867:FTRAC_RS13570
uniprot id: E4TR10
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS16050
gene id: 643867:FTRAC_RS16050
uniprot id: E4TVB9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

643867:FTRAC RS14750
gene id: 643867:FTRAC_RS14750
uniprot id: E4TSY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

643867:FTRAC RS08210
gene id: 643867:FTRAC_RS08210
uniprot id: E4TQ83
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

643867:FTRAC RS08220
gene id: 643867:FTRAC_RS08220
uniprot id: E4TQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

643867:FTRAC RS13060
gene id: 643867:FTRAC_RS13060
uniprot id: E4TPM7
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS15550
gene id: 643867:FTRAC_RS15550
uniprot id: E4TUJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643867:FTRAC RS04135
gene id: 643867:FTRAC_RS04135
uniprot id: E4TSK3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

643867:FTRAC RS18015
gene id: 643867:FTRAC_RS18015
uniprot id: E4TP41
names: Similarity
messages: Belongs to the sigma-54 factor family.

643867:FTRAC RS15450
gene id: 643867:FTRAC_RS15450
uniprot id: E4TU42
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS13820
gene id: 643867:FTRAC_RS13820
uniprot id: E4TR61
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

643867:FTRAC RS14175
gene id: 643867:FTRAC_RS14175
uniprot id: E4TS97
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

643867:FTRAC RS09695
gene id: 643867:FTRAC_RS09695
uniprot id: E4TT89
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS08200
gene id: 643867:FTRAC_RS08200
uniprot id: E4TQ81
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

643867:FTRAC RS12120
gene id: 643867:FTRAC_RS12120
uniprot id: E4TME4
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS18725
gene id: 643867:FTRAC_RS18725
uniprot id: E4TR67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

643867:FTRAC RS14390
gene id: 643867:FTRAC_RS14390
uniprot id: E4TSE0
names: Similarity
messages: Belongs to the SusD family.

643867:FTRAC RS05620
gene id: 643867:FTRAC_RS05620
uniprot id: E4TVK1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

643867:FTRAC RS18720
gene id: 643867:FTRAC_RS18720
uniprot id: E4TR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

643867:FTRAC RS12645
gene id: 643867:FTRAC_RS12645
uniprot id: E4TNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

643867:FTRAC RS15385
gene id: 643867:FTRAC_RS15385
uniprot id: E4TU29
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

643867:FTRAC RS07990
gene id: 643867:FTRAC_RS07990
uniprot id: E4TQ37
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

643867:FTRAC RS17770
gene id: 643867:FTRAC_RS17770
uniprot id: E4TNZ2
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

643867:FTRAC RS04165
gene id: 643867:FTRAC_RS04165
uniprot id: E4TSK9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS15215
gene id: 643867:FTRAC_RS15215
uniprot id: E4TTZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

643867:FTRAC RS07110
gene id: 643867:FTRAC_RS07110
uniprot id: E4TMY0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS10035
gene id: 643867:FTRAC_RS10035
uniprot id: E4TTT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

643867:FTRAC RS16730
gene id: 643867:FTRAC_RS16730
uniprot id: E4TL45
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

643867:FTRAC RS05780
gene id: 643867:FTRAC_RS05780
uniprot id: E4TVN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

643867:FTRAC RS01755
gene id: 643867:FTRAC_RS01755
uniprot id: E4TMQ8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

643867:FTRAC RS01110
gene id: 643867:FTRAC_RS01110
uniprot id: E4TL90
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

643867:FTRAC RS08930
gene id: 643867:FTRAC_RS08930
uniprot id: E4TRP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS14525
gene id: 643867:FTRAC_RS14525
uniprot id: E4TSU2
names: Similarity
messages: Belongs to the DprA/Smf family.

643867:FTRAC RS15095
gene id: 643867:FTRAC_RS15095
uniprot id: E4TTJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

643867:FTRAC RS15300
gene id: 643867:FTRAC_RS15300
uniprot id: E4TU13
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

643867:FTRAC RS04520
gene id: 643867:FTRAC_RS04520
uniprot id: E4TT51
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS14340
gene id: 643867:FTRAC_RS14340
uniprot id: E4TSC9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643867:FTRAC RS05255
gene id: 643867:FTRAC_RS05255
uniprot id: E4TUT7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bTHX family.

643867:FTRAC RS16345
gene id: 643867:FTRAC_RS16345
uniprot id: E4TW26
names: Similarity
messages: Belongs to the peptidase S9A family.

643867:FTRAC RS07470
gene id: 643867:FTRAC_RS07470
uniprot id: E4TNP5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

643867:FTRAC RS00210
gene id: 643867:FTRAC_RS00210
uniprot id: E4TUT0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

643867:FTRAC RS13530
gene id: 643867:FTRAC_RS13530
uniprot id: E4TR02
names: Subcellular Location Annotation
messages: Cytoplasm

643867:FTRAC RS13170
gene id: 643867:FTRAC_RS13170
uniprot id: E4TPP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643867:FTRAC RS05900
gene id: 643867:FTRAC_RS05900
uniprot id: E4TVQ7
names: Similarity
messages: Belongs to the pyruvate kinase family.

643867:FTRAC RS03730
gene id: 643867:FTRAC_RS03730
uniprot id: E4TRZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

643867:FTRAC RS14120
gene id: 643867:FTRAC_RS14120
uniprot id: E4TRV3
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS05735
gene id: 643867:FTRAC_RS05735
uniprot id: E4TVM3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

643867:FTRAC RS01555
gene id: 643867:FTRAC_RS01555
uniprot id: E4TM27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

643867:FTRAC RS07870
gene id: 643867:FTRAC_RS07870
uniprot id: E4TPH3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

643867:FTRAC RS13950
gene id: 643867:FTRAC_RS13950
uniprot id: E4TRR9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS07690
gene id: 643867:FTRAC_RS07690
uniprot id: E4TPD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

643867:FTRAC RS14890
gene id: 643867:FTRAC_RS14890
uniprot id: E4TTF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

643867:FTRAC RS14485
gene id: 643867:FTRAC_RS14485
uniprot id: E4TST4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS12735
gene id: 643867:FTRAC_RS12735
uniprot id: E4TNW2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

643867:FTRAC RS11945
gene id: 643867:FTRAC_RS11945
uniprot id: E4TMA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643867:FTRAC RS12600
gene id: 643867:FTRAC_RS12600
uniprot id: E4TNT4
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

643867:FTRAC RS09295
gene id: 643867:FTRAC_RS09295
uniprot id: E4TSM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643867:FTRAC RS03455
gene id: 643867:FTRAC_RS03455
uniprot id: E4TRF6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

643867:FTRAC RS07540
gene id: 643867:FTRAC_RS07540
uniprot id: E4TNQ8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

643867:FTRAC RS18530
gene id: 643867:FTRAC_RS18530
uniprot id: E4TQI6
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS17110
gene id: 643867:FTRAC_RS17110
uniprot id: E4TMG5
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS05375
gene id: 643867:FTRAC_RS05375
uniprot id: E4TUW1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643867:FTRAC RS02385
gene id: 643867:FTRAC_RS02385
uniprot id: E4TP78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS16385
gene id: 643867:FTRAC_RS16385
uniprot id: E4TW34
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

643867:FTRAC RS17885
gene id: 643867:FTRAC_RS17885
uniprot id: E4TP15
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

643867:FTRAC RS16510
gene id: 643867:FTRAC_RS16510
uniprot id: E4TL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

643867:FTRAC RS04865
gene id: 643867:FTRAC_RS04865
uniprot id: E4TTQ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

643867:FTRAC RS05130
gene id: 643867:FTRAC_RS05130
uniprot id: E4TU89
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643867:FTRAC RS17705
gene id: 643867:FTRAC_RS17705
uniprot id: E4TNC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

643867:FTRAC RS14235
gene id: 643867:FTRAC_RS14235
uniprot id: E4TSA9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS07900
gene id: 643867:FTRAC_RS07900
uniprot id: E4TPH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

643867:FTRAC RS13205
gene id: 643867:FTRAC_RS13205
uniprot id: E4TQ97
names: Similarity
messages: Belongs to the phosphohexose mutase family.

643867:FTRAC RS08480
gene id: 643867:FTRAC_RS08480
uniprot id: E4TQX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

643867:FTRAC RS17615
gene id: 643867:FTRAC_RS17615
uniprot id: E4TNA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

643867:FTRAC RS13800
gene id: 643867:FTRAC_RS13800
uniprot id: E4TR57
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

643867:FTRAC RS01570
gene id: 643867:FTRAC_RS01570
uniprot id: E4TMM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS16575
gene id: 643867:FTRAC_RS16575
uniprot id: E4TL13
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS07765
gene id: 643867:FTRAC_RS07765
uniprot id: E4TPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

643867:FTRAC RS17375
gene id: 643867:FTRAC_RS17375
uniprot id: E4TML6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643867:FTRAC RS07375
gene id: 643867:FTRAC_RS07375
uniprot id: E4TNM6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643867:FTRAC RS01415
gene id: 643867:FTRAC_RS01415
uniprot id: E4TLZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

643867:FTRAC RS07890
gene id: 643867:FTRAC_RS07890
uniprot id: E4TPH7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

643867:FTRAC RS08620
gene id: 643867:FTRAC_RS08620
uniprot id: E4TRI2
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS06855
gene id: 643867:FTRAC_RS06855
uniprot id: E4TM84
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

643867:FTRAC RS08195
gene id: 643867:FTRAC_RS08195
uniprot id: E4TQ80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

643867:FTRAC RS07330
gene id: 643867:FTRAC_RS07330
uniprot id: E4TNL7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

643867:FTRAC RS18245
gene id: 643867:FTRAC_RS18245
uniprot id: E4TPT2
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

643867:FTRAC RS15580
gene id: 643867:FTRAC_RS15580
uniprot id: E4TUJ7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

643867:FTRAC RS06835
gene id: 643867:FTRAC_RS06835
uniprot id: E4TM80
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643867:FTRAC RS18415
gene id: 643867:FTRAC_RS18415
uniprot id: E4TQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

643867:FTRAC RS04265
gene id: 643867:FTRAC_RS04265
uniprot id: E4TT01
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

643867:FTRAC RS12695
gene id: 643867:FTRAC_RS12695
uniprot id: E4TNV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643867:FTRAC RS08895
gene id: 643867:FTRAC_RS08895
uniprot id: E4TRN8
names: Similarity
messages: Belongs to the peptidase S66 family.

643867:FTRAC RS10565
gene id: 643867:FTRAC_RS10565
uniprot id: E4TUH6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643867:FTRAC RS07895
gene id: 643867:FTRAC_RS07895
uniprot id: E4TPH8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

643867:FTRAC RS13015
gene id: 643867:FTRAC_RS13015
uniprot id: E4TPL8
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS18085
gene id: 643867:FTRAC_RS18085
uniprot id: E4TPQ1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

643867:FTRAC RS14045
gene id: 643867:FTRAC_RS14045
uniprot id: E4TRT8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

643867:FTRAC RS15940
gene id: 643867:FTRAC_RS15940
uniprot id: E4TV97
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS00270
gene id: 643867:FTRAC_RS00270
uniprot id: E4TVD9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

643867:FTRAC RS15275
gene id: 643867:FTRAC_RS15275
uniprot id: E4TU07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

643867:FTRAC RS02530
gene id: 643867:FTRAC_RS02530
uniprot id: E4TPA7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

643867:FTRAC RS03200
gene id: 643867:FTRAC_RS03200
uniprot id: E4TQS8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643867:FTRAC RS19085
gene id: 643867:FTRAC_RS19085
uniprot id: E4TNJ0
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS12410
gene id: 643867:FTRAC_RS12410
uniprot id: E4TN47
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

643867:FTRAC RS09660
gene id: 643867:FTRAC_RS09660
uniprot id: E4TT82
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

643867:FTRAC RS08255
gene id: 643867:FTRAC_RS08255
uniprot id: E4TQT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

643867:FTRAC RS03625
gene id: 643867:FTRAC_RS03625
uniprot id: E4TRX2
names: Similarity
messages: Belongs to the DSD1 family.

643867:FTRAC RS03145
gene id: 643867:FTRAC_RS03145
uniprot id: E4TQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

643867:FTRAC RS09580
gene id: 643867:FTRAC_RS09580
uniprot id: E4TT67
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

643867:FTRAC RS01860
gene id: 643867:FTRAC_RS01860
uniprot id: E4TMS8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

643867:FTRAC RS15310
gene id: 643867:FTRAC_RS15310
uniprot id: E4TU15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

643867:FTRAC RS08265
gene id: 643867:FTRAC_RS08265
uniprot id: E4TQU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

643867:FTRAC RS05935
gene id: 643867:FTRAC_RS05935
uniprot id: E4TKL1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643867:FTRAC RS08575
gene id: 643867:FTRAC_RS08575
uniprot id: E4TQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

643867:FTRAC RS18625
gene id: 643867:FTRAC_RS18625
uniprot id: E4TQK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

643867:FTRAC RS14350
gene id: 643867:FTRAC_RS14350
uniprot id: E4TSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

643867:FTRAC RS15120
gene id: 643867:FTRAC_RS15120
uniprot id: E4TTX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

643867:FTRAC RS14305
gene id: 643867:FTRAC_RS14305
uniprot id: E4TSC2
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

643867:FTRAC RS12940
gene id: 643867:FTRAC_RS12940
uniprot id: E4TPK3
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS10625
gene id: 643867:FTRAC_RS10625
uniprot id: E4TV15
names: Subcellular Location Annotation
messages: Membrane

643867:FTRAC RS02995
gene id: 643867:FTRAC_RS02995
uniprot id: E4TQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

643867:FTRAC RS09765
gene id: 643867:FTRAC_RS09765
uniprot id: E4TTA3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

643867:FTRAC RS16875
gene id: 643867:FTRAC_RS16875
uniprot id: E4TLS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

643867:FTRAC RS15705
gene id: 643867:FTRAC_RS15705
uniprot id: E4TUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

643867:FTRAC RS11505
gene id: 643867:FTRAC_RS11505
uniprot id: E4TKY0
names: Subcellular Location Annotation
messages: Membrane