643561:ACAV RS22235
gene id: 643561:ACAV_RS22235
uniprot id: F0Q9B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

643561:ACAV RS04605
gene id: 643561:ACAV_RS04605
uniprot id: F0QAD3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

643561:ACAV RS09015
gene id: 643561:ACAV_RS09015
uniprot id: F0Q759
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

643561:ACAV RS11415
gene id: 643561:ACAV_RS11415
uniprot id: F0QCD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

643561:ACAV RS15290
gene id: 643561:ACAV_RS15290
uniprot id: F0Q6P0
names: Similarity
messages: Belongs to the peptidase U62 family.

643561:ACAV RS19795
gene id: 643561:ACAV_RS19795
uniprot id: F0Q3H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS07595
gene id: 643561:ACAV_RS07595
uniprot id: F0Q3T4
names: PTM
messages: Binds 1 heme c group covalently per subunit.

643561:ACAV RS17750
gene id: 643561:ACAV_RS17750
uniprot id: F0QCK0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

643561:ACAV RS13945
gene id: 643561:ACAV_RS13945
uniprot id: F0Q411
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

643561:ACAV RS20625
gene id: 643561:ACAV_RS20625
uniprot id: F0Q5W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

643561:ACAV RS20765
gene id: 643561:ACAV_RS20765
uniprot id: F0Q5Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

643561:ACAV RS15760
gene id: 643561:ACAV_RS15760
uniprot id: F0Q885
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS01405
gene id: 643561:ACAV_RS01405
uniprot id: F0Q2V2
names: Similarity
messages: Belongs to the P(II) protein family.

643561:ACAV RS04630
gene id: 643561:ACAV_RS04630
uniprot id: F0QAD8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS05770
gene id: 643561:ACAV_RS05770
uniprot id: F0QCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

643561:ACAV RS08275
gene id: 643561:ACAV_RS08275
uniprot id: F0Q5G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

643561:ACAV RS19370
gene id: 643561:ACAV_RS19370
uniprot id: F0Q2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS15795
gene id: 643561:ACAV_RS15795
uniprot id: F0Q892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS18650
gene id: 643561:ACAV_RS18650
uniprot id: F0Q0Y8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

643561:ACAV RS08800
gene id: 643561:ACAV_RS08800
uniprot id: F0Q6E5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS05305
gene id: 643561:ACAV_RS05305
uniprot id: F0QC21
names: Similarity
messages: Belongs to the asparagine synthetase family.

643561:ACAV RS17835
gene id: 643561:ACAV_RS17835
uniprot id: F0QCL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

643561:ACAV RS05270
gene id: 643561:ACAV_RS05270
uniprot id: F0QC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

643561:ACAV RS16525
gene id: 643561:ACAV_RS16525
uniprot id: F0Q9X5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS01665
gene id: 643561:ACAV_RS01665
uniprot id: F0Q3M4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS21950
gene id: 643561:ACAV_RS21950
uniprot id: F0Q8J4
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

643561:ACAV RS14485
gene id: 643561:ACAV_RS14485
uniprot id: F0Q4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

643561:ACAV RS03060
gene id: 643561:ACAV_RS03060
uniprot id: F0Q6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS09605
gene id: 643561:ACAV_RS09605
uniprot id: F0Q858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643561:ACAV RS03785
gene id: 643561:ACAV_RS03785
uniprot id: F0Q8N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

643561:ACAV RS21920
gene id: 643561:ACAV_RS21920
uniprot id: F0Q8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS02785
gene id: 643561:ACAV_RS02785
uniprot id: F0Q668
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS06715
gene id: 643561:ACAV_RS06715
uniprot id: F0Q1E5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

643561:ACAV RS23620
gene id: 643561:ACAV_RS23620
uniprot id: F0QCQ0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS21240
gene id: 643561:ACAV_RS21240
uniprot id: F0Q6V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

643561:ACAV RS13825
gene id: 643561:ACAV_RS13825
uniprot id: F0Q3B3
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

643561:ACAV RS08010
gene id: 643561:ACAV_RS08010
uniprot id: F0Q4P2
names: Similarity
messages: Belongs to the tannase family.

643561:ACAV RS08850
gene id: 643561:ACAV_RS08850
uniprot id: F0Q6F4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

643561:ACAV RS19305
gene id: 643561:ACAV_RS19305
uniprot id: F0Q2L7
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

643561:ACAV RS23525
gene id: 643561:ACAV_RS23525
uniprot id: F0QC03
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS07205
gene id: 643561:ACAV_RS07205
uniprot id: F0Q2Z2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

643561:ACAV RS23090
gene id: 643561:ACAV_RS23090
uniprot id: F0QB36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS00450
gene id: 643561:ACAV_RS00450
uniprot id: F0Q112
names: Similarity
messages: Belongs to the CobH/CbiC family.

643561:ACAV RS22755
gene id: 643561:ACAV_RS22755
uniprot id: F0QA93
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

643561:ACAV RS19095
gene id: 643561:ACAV_RS19095
uniprot id: F0Q2H7
names: Subcellular Location Annotation
messages: Cell outer membrane

643561:ACAV RS13470
gene id: 643561:ACAV_RS13470
uniprot id: F0Q345
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS09785
gene id: 643561:ACAV_RS09785
uniprot id: F0Q8W1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

643561:ACAV RS14690
gene id: 643561:ACAV_RS14690
uniprot id: F0Q5Q4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS23685
gene id: 643561:ACAV_RS23685
uniprot id: F0QCR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS07020
gene id: 643561:ACAV_RS07020
uniprot id: F0Q284
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

643561:ACAV RS00215
gene id: 643561:ACAV_RS00215
uniprot id: F0Q085
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643561:ACAV RS03925
gene id: 643561:ACAV_RS03925
uniprot id: F0Q8R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS06035
gene id: 643561:ACAV_RS06035
uniprot id: F0Q0D1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS06025
gene id: 643561:ACAV_RS06025
uniprot id: F0Q0C9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS23135
gene id: 643561:ACAV_RS23135
uniprot id: F0QB44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS11730
gene id: 643561:ACAV_RS11730
uniprot id: F0QD39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS08190
gene id: 643561:ACAV_RS08190
uniprot id: F0Q4S5
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS00960
gene id: 643561:ACAV_RS00960
uniprot id: F0Q1Z2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

643561:ACAV RS13280
gene id: 643561:ACAV_RS13280
uniprot id: F0Q2E5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS13775
gene id: 643561:ACAV_RS13775
uniprot id: F0Q3A4
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

643561:ACAV RS06505
gene id: 643561:ACAV_RS06505
uniprot id: F0Q1A2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS17210
gene id: 643561:ACAV_RS17210
uniprot id: F0QBL9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS00245
gene id: 643561:ACAV_RS00245
uniprot id: F0Q093
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS08595
gene id: 643561:ACAV_RS08595
uniprot id: F0Q5M9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS17735
gene id: 643561:ACAV_RS17735
uniprot id: F0QCJ7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

643561:ACAV RS14110
gene id: 643561:ACAV_RS14110
uniprot id: F0Q444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS01265
gene id: 643561:ACAV_RS01265
uniprot id: F0Q2S4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643561:ACAV RS04540
gene id: 643561:ACAV_RS04540
uniprot id: F0QAC0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS01960
gene id: 643561:ACAV_RS01960
uniprot id: F0Q4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

643561:ACAV RS21150
gene id: 643561:ACAV_RS21150
uniprot id: F0Q6U4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS06805
gene id: 643561:ACAV_RS06805
uniprot id: F0Q240
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

643561:ACAV RS13430
gene id: 643561:ACAV_RS13430
uniprot id: F0Q2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

643561:ACAV RS23010
gene id: 643561:ACAV_RS23010
uniprot id: F0QB18
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

643561:ACAV RS07550
gene id: 643561:ACAV_RS07550
uniprot id: F0Q3S4
names: Similarity
messages: Belongs to the type IB topoisomerase family.

643561:ACAV RS24310
gene id: 643561:ACAV_RS24310
uniprot id: F0QCN8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

643561:ACAV RS06145
gene id: 643561:ACAV_RS06145
uniprot id: F0Q0F4
names: Similarity
messages: Belongs to the threonine synthase family.

643561:ACAV RS08655
gene id: 643561:ACAV_RS08655
uniprot id: F0Q6B6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643561:ACAV RS17520
gene id: 643561:ACAV_RS17520
uniprot id: F0QBS8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS06665
gene id: 643561:ACAV_RS06665
uniprot id: F0Q1D5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS20875
gene id: 643561:ACAV_RS20875
uniprot id: F0Q615
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS22055
gene id: 643561:ACAV_RS22055
uniprot id: F0Q8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

643561:ACAV RS23965
gene id: 643561:ACAV_RS23965
uniprot id: F0Q688
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

643561:ACAV RS19270
gene id: 643561:ACAV_RS19270
uniprot id: F0Q2L0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

643561:ACAV RS09745
gene id: 643561:ACAV_RS09745
uniprot id: F0Q8V3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

643561:ACAV RS20065
gene id: 643561:ACAV_RS20065
uniprot id: F0Q4A5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GmhB family.
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS02920
gene id: 643561:ACAV_RS02920
uniprot id: F0Q695
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

643561:ACAV RS05705
gene id: 643561:ACAV_RS05705
uniprot id: F0QCU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

643561:ACAV RS13635
gene id: 643561:ACAV_RS13635
uniprot id: F0Q378
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

643561:ACAV RS13640
gene id: 643561:ACAV_RS13640
uniprot id: F0Q379
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

643561:ACAV RS15075
gene id: 643561:ACAV_RS15075
uniprot id: F0Q6J7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643561:ACAV RS21375
gene id: 643561:ACAV_RS21375
uniprot id: F0Q7L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

643561:ACAV RS08520
gene id: 643561:ACAV_RS08520
uniprot id: F0Q5L5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS12240
gene id: 643561:ACAV_RS12240
uniprot id: F0QDE2
names: Similarity
messages: Belongs to the PrpF family.

643561:ACAV RS07380
gene id: 643561:ACAV_RS07380
uniprot id: F0Q319
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

643561:ACAV RS01380
gene id: 643561:ACAV_RS01380
uniprot id: F0Q2U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS18585
gene id: 643561:ACAV_RS18585
uniprot id: F0Q0X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

643561:ACAV RS03665
gene id: 643561:ACAV_RS03665
uniprot id: F0Q7Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS01955
gene id: 643561:ACAV_RS01955
uniprot id: F0Q4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

643561:ACAV RS18795
gene id: 643561:ACAV_RS18795
uniprot id: F0Q1P2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

643561:ACAV RS04795
gene id: 643561:ACAV_RS04795
uniprot id: F0QAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS09555
gene id: 643561:ACAV_RS09555
uniprot id: F0Q848
names: Similarity
messages: Belongs to the UPF0751 family.

643561:ACAV RS11795
gene id: 643561:ACAV_RS11795
uniprot id: F0QD52
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643561:ACAV RS04645
gene id: 643561:ACAV_RS04645
uniprot id: F0QAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

643561:ACAV RS09635
gene id: 643561:ACAV_RS09635
uniprot id: F0Q864
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

643561:ACAV RS02105
gene id: 643561:ACAV_RS02105
uniprot id: F0Q4I6
names: Similarity
messages: Belongs to the UPF0250 family.

643561:ACAV RS03565
gene id: 643561:ACAV_RS03565
uniprot id: F0Q7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

643561:ACAV RS13405
gene id: 643561:ACAV_RS13405
uniprot id: F0Q2G8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

643561:ACAV RS20790
gene id: 643561:ACAV_RS20790
uniprot id: F0Q5Z8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS21315
gene id: 643561:ACAV_RS21315
uniprot id: F0Q6X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

643561:ACAV RS20200
gene id: 643561:ACAV_RS20200
uniprot id: F0Q4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

643561:ACAV RS02870
gene id: 643561:ACAV_RS02870
uniprot id: F0Q685
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

643561:ACAV RS09030
gene id: 643561:ACAV_RS09030
uniprot id: F0Q762
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

643561:ACAV RS16345
gene id: 643561:ACAV_RS16345
uniprot id: F0Q969
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS11245
gene id: 643561:ACAV_RS11245
uniprot id: F0QC98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

643561:ACAV RS08815
gene id: 643561:ACAV_RS08815
uniprot id: F0Q6E7
names: Similarity
messages: Belongs to the peptidase M1 family.

643561:ACAV RS13980
gene id: 643561:ACAV_RS13980
uniprot id: F0Q418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS04635
gene id: 643561:ACAV_RS04635
uniprot id: F0QAD9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

643561:ACAV RS04515
gene id: 643561:ACAV_RS04515
uniprot id: F0QAB5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

643561:ACAV RS09380
gene id: 643561:ACAV_RS09380
uniprot id: F0Q812
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS00240
gene id: 643561:ACAV_RS00240
uniprot id: F0Q092
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

643561:ACAV RS06085
gene id: 643561:ACAV_RS06085
uniprot id: F0Q0E2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

643561:ACAV RS03835
gene id: 643561:ACAV_RS03835
uniprot id: F0Q8P3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

643561:ACAV RS07585
gene id: 643561:ACAV_RS07585
uniprot id: F0Q3T2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS23705
gene id: 643561:ACAV_RS23705
uniprot id: F0QCR6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

643561:ACAV RS17925
gene id: 643561:ACAV_RS17925
uniprot id: F0QCN3
names: Similarity
messages: Belongs to the RecJ family.

643561:ACAV RS13050
gene id: 643561:ACAV_RS13050
uniprot id: F0Q1M4
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

643561:ACAV RS02945
gene id: 643561:ACAV_RS02945
uniprot id: F0Q6A0
names: Similarity
messages: Belongs to the GSP E family.

643561:ACAV RS05015
gene id: 643561:ACAV_RS05015
uniprot id: F0QB86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

643561:ACAV RS09900
gene id: 643561:ACAV_RS09900
uniprot id: F0Q8Y3
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

643561:ACAV RS11905
gene id: 643561:ACAV_RS11905
uniprot id: F0QD75
names: Subcellular Location Annotation
messages: Nucleus

643561:ACAV RS17640
gene id: 643561:ACAV_RS17640
uniprot id: F0QCH8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

643561:ACAV RS21610
gene id: 643561:ACAV_RS21610
uniprot id: F0Q7Q7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS06355
gene id: 643561:ACAV_RS06355
uniprot id: F0Q0J5
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS04520
gene id: 643561:ACAV_RS04520
uniprot id: F0QAB6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

643561:ACAV RS11440
gene id: 643561:ACAV_RS11440
uniprot id: F0QCD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

643561:ACAV RS21290
gene id: 643561:ACAV_RS21290
uniprot id: F0Q6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

643561:ACAV RS15585
gene id: 643561:ACAV_RS15585
uniprot id: F0Q7H4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

643561:ACAV RS08155
gene id: 643561:ACAV_RS08155
uniprot id: F0Q4R8
names: Similarity
messages: Belongs to the UxaA family.

643561:ACAV RS23465
gene id: 643561:ACAV_RS23465
uniprot id: F0QBZ0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

643561:ACAV RS02460
gene id: 643561:ACAV_RS02460
uniprot id: F0Q5D0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

643561:ACAV RS05830
gene id: 643561:ACAV_RS05830
uniprot id: F0QCX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

643561:ACAV RS11460
gene id: 643561:ACAV_RS11460
uniprot id: F0QCD9
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

643561:ACAV RS14580
gene id: 643561:ACAV_RS14580
uniprot id: F0Q508
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS10620
gene id: 643561:ACAV_RS10620
uniprot id: F0QAM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS23695
gene id: 643561:ACAV_RS23695
uniprot id: F0QCR4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

643561:ACAV RS12720
gene id: 643561:ACAV_RS12720
uniprot id: F0Q1F8
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

643561:ACAV RS05700
gene id: 643561:ACAV_RS05700
uniprot id: F0QCU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

643561:ACAV RS20400
gene id: 643561:ACAV_RS20400
uniprot id: F0Q547
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

643561:ACAV RS19975
gene id: 643561:ACAV_RS19975
uniprot id: F0Q487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS14595
gene id: 643561:ACAV_RS14595
uniprot id: F0Q5N5
names: Similarity
messages: Belongs to the citrate synthase family.

643561:ACAV RS12895
gene id: 643561:ACAV_RS12895
uniprot id: F0Q1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS20860
gene id: 643561:ACAV_RS20860
uniprot id: F0Q612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS10075
gene id: 643561:ACAV_RS10075
uniprot id: F0Q9N4
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS21115
gene id: 643561:ACAV_RS21115
uniprot id: F0Q6T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS11975
gene id: 643561:ACAV_RS11975
uniprot id: F0QD88
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

643561:ACAV RS22295
gene id: 643561:ACAV_RS22295
uniprot id: F0Q9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

643561:ACAV RS13435
gene id: 643561:ACAV_RS13435
uniprot id: F0Q2H4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS11710
gene id: 643561:ACAV_RS11710
uniprot id: F0QD35
names: Similarity
messages: Belongs to the thioesterase PaaI family.

643561:ACAV RS14070
gene id: 643561:ACAV_RS14070
uniprot id: F0Q436
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643561:ACAV RS06500
gene id: 643561:ACAV_RS06500
uniprot id: F0Q1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS12370
gene id: 643561:ACAV_RS12370
uniprot id: F0Q0L1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS03315
gene id: 643561:ACAV_RS03315
uniprot id: F0Q745
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS22980
gene id: 643561:ACAV_RS22980
uniprot id: F0QB12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

643561:ACAV RS05905
gene id: 643561:ACAV_RS05905
uniprot id: F0QCY7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643561:ACAV RS07950
gene id: 643561:ACAV_RS07950
uniprot id: F0Q4N0
names: Subcellular Location Annotation
messages: Cytoplasm

643561:ACAV RS18855
gene id: 643561:ACAV_RS18855
uniprot id: F0Q1Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

643561:ACAV RS02830
gene id: 643561:ACAV_RS02830
uniprot id: F0Q677
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

643561:ACAV RS15635
gene id: 643561:ACAV_RS15635
uniprot id: F0Q7I4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

643561:ACAV RS05010
gene id: 643561:ACAV_RS05010
uniprot id: F0QB85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

643561:ACAV RS05190
gene id: 643561:ACAV_RS05190
uniprot id: F0QBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

643561:ACAV RS05140
gene id: 643561:ACAV_RS05140
uniprot id: F0QBB3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS21295
gene id: 643561:ACAV_RS21295
uniprot id: F0Q6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

643561:ACAV RS06840
gene id: 643561:ACAV_RS06840
uniprot id: F0Q247
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS21560
gene id: 643561:ACAV_RS21560
uniprot id: F0Q7P6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS10680
gene id: 643561:ACAV_RS10680
uniprot id: F0QAN3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS05925
gene id: 643561:ACAV_RS05925
uniprot id: F0QCZ1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

643561:ACAV RS15520
gene id: 643561:ACAV_RS15520
uniprot id: F0Q7G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

643561:ACAV RS19875
gene id: 643561:ACAV_RS19875
uniprot id: F0Q467
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS07200
gene id: 643561:ACAV_RS07200
uniprot id: F0Q2Z1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

643561:ACAV RS09325
gene id: 643561:ACAV_RS09325
uniprot id: F0Q7C4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS08385
gene id: 643561:ACAV_RS08385
uniprot id: F0Q5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS15890
gene id: 643561:ACAV_RS15890
uniprot id: F0Q8B1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS16425
gene id: 643561:ACAV_RS16425
uniprot id: F0Q985
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS11370
gene id: 643561:ACAV_RS11370
uniprot id: F0QCC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

643561:ACAV RS21380
gene id: 643561:ACAV_RS21380
uniprot id: F0Q7L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

643561:ACAV RS15145
gene id: 643561:ACAV_RS15145
uniprot id: F0Q6L1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

643561:ACAV RS17670
gene id: 643561:ACAV_RS17670
uniprot id: F0QCI4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

643561:ACAV RS04120
gene id: 643561:ACAV_RS04120
uniprot id: F0Q9G1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

643561:ACAV RS23730
gene id: 643561:ACAV_RS23730
uniprot id: F0QCS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS09770
gene id: 643561:ACAV_RS09770
uniprot id: F0Q8V8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

643561:ACAV RS18045
gene id: 643561:ACAV_RS18045
uniprot id: F0QDH9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS10470
gene id: 643561:ACAV_RS10470
uniprot id: F0QAJ1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS22155
gene id: 643561:ACAV_RS22155
uniprot id: F0Q994
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

643561:ACAV RS14470
gene id: 643561:ACAV_RS14470
uniprot id: F0Q4Y6
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS17720
gene id: 643561:ACAV_RS17720
uniprot id: F0QCJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS13655
gene id: 643561:ACAV_RS13655
uniprot id: F0Q382
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS08700
gene id: 643561:ACAV_RS08700
uniprot id: F0Q6C5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

643561:ACAV RS15320
gene id: 643561:ACAV_RS15320
uniprot id: F0Q6P6
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

643561:ACAV RS05765
gene id: 643561:ACAV_RS05765
uniprot id: F0QCV9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

643561:ACAV RS09670
gene id: 643561:ACAV_RS09670
uniprot id: F0Q871
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

643561:ACAV RS01330
gene id: 643561:ACAV_RS01330
uniprot id: F0Q2T7
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

643561:ACAV RS00440
gene id: 643561:ACAV_RS00440
uniprot id: F0Q110
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

643561:ACAV RS00580
gene id: 643561:ACAV_RS00580
uniprot id: F0Q141
names: Similarity
messages: Belongs to the YciI family.

643561:ACAV RS19045
gene id: 643561:ACAV_RS19045
uniprot id: F0Q1U2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

643561:ACAV RS14940
gene id: 643561:ACAV_RS14940
uniprot id: F0Q5V5
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS12690
gene id: 643561:ACAV_RS12690
uniprot id: F0Q1F2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS07530
gene id: 643561:ACAV_RS07530
uniprot id: F0Q3S0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

643561:ACAV RS04780
gene id: 643561:ACAV_RS04780
uniprot id: F0QAG8
names: Similarity
messages: Belongs to the glutamate synthase family.

643561:ACAV RS14510
gene id: 643561:ACAV_RS14510
uniprot id: F0Q4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS17275
gene id: 643561:ACAV_RS17275
uniprot id: F0QBN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

643561:ACAV RS02005
gene id: 643561:ACAV_RS02005
uniprot id: F0Q4G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

643561:ACAV RS07775
gene id: 643561:ACAV_RS07775
uniprot id: F0Q3X1
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

643561:ACAV RS03150
gene id: 643561:ACAV_RS03150
uniprot id: F0Q711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS02535
gene id: 643561:ACAV_RS02535
uniprot id: F0Q5E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS04385
gene id: 643561:ACAV_RS04385
uniprot id: F0Q9L5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS20040
gene id: 643561:ACAV_RS20040
uniprot id: F0Q4A0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS18860
gene id: 643561:ACAV_RS18860
uniprot id: F0Q1Q5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS15125
gene id: 643561:ACAV_RS15125
uniprot id: F0Q6K7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

643561:ACAV RS07650
gene id: 643561:ACAV_RS07650
uniprot id: F0Q3U6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS12070
gene id: 643561:ACAV_RS12070
uniprot id: F0QDA7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

643561:ACAV RS11085
gene id: 643561:ACAV_RS11085
uniprot id: F0QBJ2
names: PTM
messages: Binds 1 heme c group covalently per subunit.

643561:ACAV RS20385
gene id: 643561:ACAV_RS20385
uniprot id: F0Q544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

643561:ACAV RS02280
gene id: 643561:ACAV_RS02280
uniprot id: F0Q594
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS05620
gene id: 643561:ACAV_RS05620
uniprot id: F0QCS9
names: Similarity
messages: Belongs to the peptidase S45 family.

643561:ACAV RS04670
gene id: 643561:ACAV_RS04670
uniprot id: F0QAE6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

643561:ACAV RS19630
gene id: 643561:ACAV_RS19630
uniprot id: F0Q3E6
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS06060
gene id: 643561:ACAV_RS06060
uniprot id: F0Q0D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

643561:ACAV RS02960
gene id: 643561:ACAV_RS02960
uniprot id: F0Q6A3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

643561:ACAV RS09055
gene id: 643561:ACAV_RS09055
uniprot id: F0Q767
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS03405
gene id: 643561:ACAV_RS03405
uniprot id: F0Q7U0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS05210
gene id: 643561:ACAV_RS05210
uniprot id: F0QBC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

643561:ACAV RS07800
gene id: 643561:ACAV_RS07800
uniprot id: F0Q3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

643561:ACAV RS20585
gene id: 643561:ACAV_RS20585
uniprot id: F0Q584
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS07935
gene id: 643561:ACAV_RS07935
uniprot id: F0Q4M7
names: Similarity
messages: Belongs to the SUI1 family.

643561:ACAV RS15580
gene id: 643561:ACAV_RS15580
uniprot id: F0Q7H3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

643561:ACAV RS19260
gene id: 643561:ACAV_RS19260
uniprot id: F0Q2K8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS03525
gene id: 643561:ACAV_RS03525
uniprot id: F0Q7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

643561:ACAV RS00760
gene id: 643561:ACAV_RS00760
uniprot id: F0Q177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

643561:ACAV RS21455
gene id: 643561:ACAV_RS21455
uniprot id: F0Q7M6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

643561:ACAV RS12880
gene id: 643561:ACAV_RS12880
uniprot id: F0Q1J0
names: Similarity
messages: Belongs to the HIBADH-related family.

643561:ACAV RS14450
gene id: 643561:ACAV_RS14450
uniprot id: F0Q4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643561:ACAV RS17965
gene id: 643561:ACAV_RS17965
uniprot id: F0QDG4
names: Similarity
messages: Belongs to the ArsC family.

643561:ACAV RS05890
gene id: 643561:ACAV_RS05890
uniprot id: F0QCY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

643561:ACAV RS02810
gene id: 643561:ACAV_RS02810
uniprot id: F0Q673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS02905
gene id: 643561:ACAV_RS02905
uniprot id: F0Q693
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

643561:ACAV RS01045
gene id: 643561:ACAV_RS01045
uniprot id: F0Q209
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

643561:ACAV RS10760
gene id: 643561:ACAV_RS10760
uniprot id: F0QAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

643561:ACAV RS02130
gene id: 643561:ACAV_RS02130
uniprot id: F0Q4J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

643561:ACAV RS03025
gene id: 643561:ACAV_RS03025
uniprot id: F0Q6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS00600
gene id: 643561:ACAV_RS00600
uniprot id: F0Q145
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

643561:ACAV RS07335
gene id: 643561:ACAV_RS07335
uniprot id: F0Q313
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643561:ACAV RS03310
gene id: 643561:ACAV_RS03310
uniprot id: F0Q744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

643561:ACAV RS12620
gene id: 643561:ACAV_RS12620
uniprot id: F0Q0R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

643561:ACAV RS04400
gene id: 643561:ACAV_RS04400
uniprot id: F0Q9L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

643561:ACAV RS15235
gene id: 643561:ACAV_RS15235
uniprot id: F0Q6M9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS15535
gene id: 643561:ACAV_RS15535
uniprot id: F0Q7G3
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS18065
gene id: 643561:ACAV_RS18065
uniprot id: F0QDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS08920
gene id: 643561:ACAV_RS08920
uniprot id: F0Q6G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

643561:ACAV RS05205
gene id: 643561:ACAV_RS05205
uniprot id: F0QBC6
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

643561:ACAV RS03645
gene id: 643561:ACAV_RS03645
uniprot id: F0Q7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

643561:ACAV RS05675
gene id: 643561:ACAV_RS05675
uniprot id: F0QCU0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

643561:ACAV RS20815
gene id: 643561:ACAV_RS20815
uniprot id: F0Q603
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

643561:ACAV RS22090
gene id: 643561:ACAV_RS22090
uniprot id: F0Q990
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

643561:ACAV RS06465
gene id: 643561:ACAV_RS06465
uniprot id: F0Q194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS04860
gene id: 643561:ACAV_RS04860
uniprot id: F0QB55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

643561:ACAV RS18140
gene id: 643561:ACAV_RS18140
uniprot id: F0QDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS02745
gene id: 643561:ACAV_RS02745
uniprot id: F0Q660
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

643561:ACAV RS02470
gene id: 643561:ACAV_RS02470
uniprot id: F0Q5D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

643561:ACAV RS07375
gene id: 643561:ACAV_RS07375
uniprot id: F0Q318
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

643561:ACAV RS22565
gene id: 643561:ACAV_RS22565
uniprot id: F0QA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643561:ACAV RS18395
gene id: 643561:ACAV_RS18395
uniprot id: F0Q0T8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

643561:ACAV RS19680
gene id: 643561:ACAV_RS19680
uniprot id: F0Q3F6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

643561:ACAV RS13005
gene id: 643561:ACAV_RS13005
uniprot id: F0Q1L5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS06015
gene id: 643561:ACAV_RS06015
uniprot id: F0Q0C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

643561:ACAV RS06080
gene id: 643561:ACAV_RS06080
uniprot id: F0Q0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

643561:ACAV RS04185
gene id: 643561:ACAV_RS04185
uniprot id: F0Q9H5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

643561:ACAV RS06970
gene id: 643561:ACAV_RS06970
uniprot id: F0Q274
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS12655
gene id: 643561:ACAV_RS12655
uniprot id: F0Q0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

643561:ACAV RS03285
gene id: 643561:ACAV_RS03285
uniprot id: F0Q739
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS17525
gene id: 643561:ACAV_RS17525
uniprot id: F0QBS9
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

643561:ACAV RS20505
gene id: 643561:ACAV_RS20505
uniprot id: F0Q568
names: Similarity
messages: Belongs to the DEAD box helicase family.

643561:ACAV RS23365
gene id: 643561:ACAV_RS23365
uniprot id: F0QBX0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS06195
gene id: 643561:ACAV_RS06195
uniprot id: F0Q0G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

643561:ACAV RS13170
gene id: 643561:ACAV_RS13170
uniprot id: F0Q2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

643561:ACAV RS06050
gene id: 643561:ACAV_RS06050
uniprot id: F0Q0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

643561:ACAV RS23640
gene id: 643561:ACAV_RS23640
uniprot id: F0QCQ3
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS16970
gene id: 643561:ACAV_RS16970
uniprot id: F0QAT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

643561:ACAV RS12320
gene id: 643561:ACAV_RS12320
uniprot id: F0Q0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS11700
gene id: 643561:ACAV_RS11700
uniprot id: F0QD33
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS05395
gene id: 643561:ACAV_RS05395
uniprot id: F0QC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

643561:ACAV RS20980
gene id: 643561:ACAV_RS20980
uniprot id: F0Q6Q9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

643561:ACAV RS24225
gene id: 643561:ACAV_RS24225
uniprot id: F0Q0Z6
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS00680
gene id: 643561:ACAV_RS00680
uniprot id: F0Q161
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS02075
gene id: 643561:ACAV_RS02075
uniprot id: F0Q4I0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS02290
gene id: 643561:ACAV_RS02290
uniprot id: F0Q596
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

643561:ACAV RS09590
gene id: 643561:ACAV_RS09590
uniprot id: F0Q855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

643561:ACAV RS15450
gene id: 643561:ACAV_RS15450
uniprot id: F0Q7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

643561:ACAV RS01990
gene id: 643561:ACAV_RS01990
uniprot id: F0Q4G2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

643561:ACAV RS20785
gene id: 643561:ACAV_RS20785
uniprot id: F0Q5Z7
names: Subcellular Location Annotation
messages: Periplasm

643561:ACAV RS18130
gene id: 643561:ACAV_RS18130
uniprot id: F0QDJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS16255
gene id: 643561:ACAV_RS16255
uniprot id: F0Q951
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS07170
gene id: 643561:ACAV_RS07170
uniprot id: F0Q2Y5
names: Similarity
messages: Belongs to the YfgM family.

643561:ACAV RS19815
gene id: 643561:ACAV_RS19815
uniprot id: F0Q3I3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

643561:ACAV RS15825
gene id: 643561:ACAV_RS15825
uniprot id: F0Q898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

643561:ACAV RS11605
gene id: 643561:ACAV_RS11605
uniprot id: F0QD14
names: Similarity
messages: Belongs to the BolA/IbaG family.

643561:ACAV RS01985
gene id: 643561:ACAV_RS01985
uniprot id: F0Q4G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

643561:ACAV RS20080
gene id: 643561:ACAV_RS20080
uniprot id: F0Q4A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643561:ACAV RS10095
gene id: 643561:ACAV_RS10095
uniprot id: F0Q9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

643561:ACAV RS04810
gene id: 643561:ACAV_RS04810
uniprot id: F0QAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS15845
gene id: 643561:ACAV_RS15845
uniprot id: F0Q8A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

643561:ACAV RS17060
gene id: 643561:ACAV_RS17060
uniprot id: F0QAW0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

643561:ACAV RS06680
gene id: 643561:ACAV_RS06680
uniprot id: F0Q1D8
names: Similarity
messages: Belongs to the Gfa family.

643561:ACAV RS17710
gene id: 643561:ACAV_RS17710
uniprot id: F0QCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643561:ACAV RS13515
gene id: 643561:ACAV_RS13515
uniprot id: F0Q354
names: Similarity
messages: Belongs to the GSP E family.

643561:ACAV RS03380
gene id: 643561:ACAV_RS03380
uniprot id: F0Q7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS04970
gene id: 643561:ACAV_RS04970
uniprot id: F0QB77
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

643561:ACAV RS16955
gene id: 643561:ACAV_RS16955
uniprot id: F0QAT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

643561:ACAV RS20395
gene id: 643561:ACAV_RS20395
uniprot id: F0Q546
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS09765
gene id: 643561:ACAV_RS09765
uniprot id: F0Q8V7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS12535
gene id: 643561:ACAV_RS12535
uniprot id: F0Q0P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

643561:ACAV RS06900
gene id: 643561:ACAV_RS06900
uniprot id: F0Q259
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

643561:ACAV RS22315
gene id: 643561:ACAV_RS22315
uniprot id: F0Q9C6
names: Similarity
messages: Belongs to the peptidase S13 family.

643561:ACAV RS08810
gene id: 643561:ACAV_RS08810
uniprot id: F0Q6E6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS12180
gene id: 643561:ACAV_RS12180
uniprot id: F0QDD0
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

643561:ACAV RS07195
gene id: 643561:ACAV_RS07195
uniprot id: F0Q2Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

643561:ACAV RS04415
gene id: 643561:ACAV_RS04415
uniprot id: F0Q9M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS22725
gene id: 643561:ACAV_RS22725
uniprot id: F0QA87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

643561:ACAV RS06310
gene id: 643561:ACAV_RS06310
uniprot id: F0Q0I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

643561:ACAV RS19480
gene id: 643561:ACAV_RS19480
uniprot id: F0Q3B6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS09760
gene id: 643561:ACAV_RS09760
uniprot id: F0Q8V6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

643561:ACAV RS22575
gene id: 643561:ACAV_RS22575
uniprot id: F0QA55
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS20350
gene id: 643561:ACAV_RS20350
uniprot id: F0Q537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS06650
gene id: 643561:ACAV_RS06650
uniprot id: F0Q1D2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

643561:ACAV RS13800
gene id: 643561:ACAV_RS13800
uniprot id: F0Q3A8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

643561:ACAV RS21405
gene id: 643561:ACAV_RS21405
uniprot id: F0Q7L6
names: Subcellular Location Annotation
messages: Periplasm

643561:ACAV RS06765
gene id: 643561:ACAV_RS06765
uniprot id: F0Q231
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

643561:ACAV RS00770
gene id: 643561:ACAV_RS00770
uniprot id: F0Q1V3
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

643561:ACAV RS21430
gene id: 643561:ACAV_RS21430
uniprot id: F0Q7M1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

643561:ACAV RS11530
gene id: 643561:ACAV_RS11530
uniprot id: F0QCF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS19445
gene id: 643561:ACAV_RS19445
uniprot id: F0Q2P4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS09190
gene id: 643561:ACAV_RS09190
uniprot id: F0Q796
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

643561:ACAV RS05540
gene id: 643561:ACAV_RS05540
uniprot id: F0QC69
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS10865
gene id: 643561:ACAV_RS10865
uniprot id: F0QBE8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

643561:ACAV RS06515
gene id: 643561:ACAV_RS06515
uniprot id: F0Q1A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS04870
gene id: 643561:ACAV_RS04870
uniprot id: F0QB57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

643561:ACAV RS22065
gene id: 643561:ACAV_RS22065
uniprot id: F0Q8L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643561:ACAV RS18665
gene id: 643561:ACAV_RS18665
uniprot id: F0Q0Z1
names: Similarity
messages: Belongs to the peptidase S41A family.

643561:ACAV RS01255
gene id: 643561:ACAV_RS01255
uniprot id: F0Q2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS21700
gene id: 643561:ACAV_RS21700
uniprot id: F0Q7S5
names: Similarity
messages: Belongs to the universal stress protein A family.

643561:ACAV RS12965
gene id: 643561:ACAV_RS12965
uniprot id: F0Q1K7
names: Similarity
messages: Belongs to the peptidase S8 family.

643561:ACAV RS10610
gene id: 643561:ACAV_RS10610
uniprot id: F0QAL9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

643561:ACAV RS17265
gene id: 643561:ACAV_RS17265
uniprot id: F0QBN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

643561:ACAV RS10395
gene id: 643561:ACAV_RS10395
uniprot id: F0Q9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

643561:ACAV RS12250
gene id: 643561:ACAV_RS12250
uniprot id: F0QDE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

643561:ACAV RS17130
gene id: 643561:ACAV_RS17130
uniprot id: F0QAX4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

643561:ACAV RS03840
gene id: 643561:ACAV_RS03840
uniprot id: F0Q8P5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

643561:ACAV RS10530
gene id: 643561:ACAV_RS10530
uniprot id: F0QAK3
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

643561:ACAV RS02640
gene id: 643561:ACAV_RS02640
uniprot id: F0Q638
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

643561:ACAV RS06590
gene id: 643561:ACAV_RS06590
uniprot id: F0Q1B9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS02145
gene id: 643561:ACAV_RS02145
uniprot id: F0Q4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

643561:ACAV RS15505
gene id: 643561:ACAV_RS15505
uniprot id: F0Q7F7
names: Similarity
messages: Belongs to the ModE family.

643561:ACAV RS16330
gene id: 643561:ACAV_RS16330
uniprot id: F0Q966
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

643561:ACAV RS04695
gene id: 643561:ACAV_RS04695
uniprot id: F0QAF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

643561:ACAV RS15200
gene id: 643561:ACAV_RS15200
uniprot id: F0Q6M2
names: Similarity
messages: Belongs to the GST superfamily.

643561:ACAV RS04820
gene id: 643561:ACAV_RS04820
uniprot id: F0QAH6
names: Similarity
messages: Belongs to the MlaA family.

643561:ACAV RS16190
gene id: 643561:ACAV_RS16190
uniprot id: F0Q938
names: Similarity
messages: Belongs to the DEAD box helicase family.

643561:ACAV RS17885
gene id: 643561:ACAV_RS17885
uniprot id: F0QCM5
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

643561:ACAV RS05545
gene id: 643561:ACAV_RS05545
uniprot id: F0QC70
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS08880
gene id: 643561:ACAV_RS08880
uniprot id: F0Q6G0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

643561:ACAV RS17305
gene id: 643561:ACAV_RS17305
uniprot id: F0QBN8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

643561:ACAV RS11345
gene id: 643561:ACAV_RS11345
uniprot id: F0QCB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

643561:ACAV RS06165
gene id: 643561:ACAV_RS06165
uniprot id: F0Q0F8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

643561:ACAV RS12010
gene id: 643561:ACAV_RS12010
uniprot id: F0QD95
names: Similarity
messages: Belongs to the heme-containing dehydratase family.

643561:ACAV RS06290
gene id: 643561:ACAV_RS06290
uniprot id: F0Q0I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS21425
gene id: 643561:ACAV_RS21425
uniprot id: F0Q7M0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

643561:ACAV RS08360
gene id: 643561:ACAV_RS08360
uniprot id: F0Q5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

643561:ACAV RS17475
gene id: 643561:ACAV_RS17475
uniprot id: F0QBR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS19800
gene id: 643561:ACAV_RS19800
uniprot id: F0Q3I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS03615
gene id: 643561:ACAV_RS03615
uniprot id: F0Q7Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

643561:ACAV RS18630
gene id: 643561:ACAV_RS18630
uniprot id: F0Q0Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

643561:ACAV RS07790
gene id: 643561:ACAV_RS07790
uniprot id: F0Q3X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

643561:ACAV RS08750
gene id: 643561:ACAV_RS08750
uniprot id: F0Q6D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

643561:ACAV RS12905
gene id: 643561:ACAV_RS12905
uniprot id: F0Q1J5
names: Similarity
messages: Belongs to the UxaA family.

643561:ACAV RS12725
gene id: 643561:ACAV_RS12725
uniprot id: F0Q1F9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

643561:ACAV RS22640
gene id: 643561:ACAV_RS22640
uniprot id: F0QA70
names: Similarity
messages: Belongs to the type IA topoisomerase family.

643561:ACAV RS10745
gene id: 643561:ACAV_RS10745
uniprot id: F0QAP7
names: Similarity
messages: Belongs to the peptidase S11 family.

643561:ACAV RS21120
gene id: 643561:ACAV_RS21120
uniprot id: F0Q6T8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS03290
gene id: 643561:ACAV_RS03290
uniprot id: F0Q740
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS02865
gene id: 643561:ACAV_RS02865
uniprot id: F0Q684
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

643561:ACAV RS09610
gene id: 643561:ACAV_RS09610
uniprot id: F0Q859
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

643561:ACAV RS09680
gene id: 643561:ACAV_RS09680
uniprot id: F0Q873
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS03720
gene id: 643561:ACAV_RS03720
uniprot id: F0Q803
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

643561:ACAV RS15565
gene id: 643561:ACAV_RS15565
uniprot id: F0Q7G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS16390
gene id: 643561:ACAV_RS16390
uniprot id: F0Q978
names: Similarity
messages: Belongs to the UPF0502 family.

643561:ACAV RS04590
gene id: 643561:ACAV_RS04590
uniprot id: F0QAD0
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

643561:ACAV RS14645
gene id: 643561:ACAV_RS14645
uniprot id: F0Q5P5
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

643561:ACAV RS15435
gene id: 643561:ACAV_RS15435
uniprot id: F0Q7E3
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

643561:ACAV RS10150
gene id: 643561:ACAV_RS10150
uniprot id: F0Q9Q1
names: Similarity
messages: Belongs to the GST superfamily.

643561:ACAV RS16960
gene id: 643561:ACAV_RS16960
uniprot id: F0QAT7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

643561:ACAV RS12945
gene id: 643561:ACAV_RS12945
uniprot id: F0Q1K3
names: Similarity
messages: Belongs to the DapA family.

643561:ACAV RS02135
gene id: 643561:ACAV_RS02135
uniprot id: F0Q4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

643561:ACAV RS00305
gene id: 643561:ACAV_RS00305
uniprot id: F0Q0A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

643561:ACAV RS14990
gene id: 643561:ACAV_RS14990
uniprot id: F0Q6I0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

643561:ACAV RS19755
gene id: 643561:ACAV_RS19755
uniprot id: F0Q3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS13670
gene id: 643561:ACAV_RS13670
uniprot id: F0Q385
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

643561:ACAV RS06905
gene id: 643561:ACAV_RS06905
uniprot id: F0Q260
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

643561:ACAV RS08335
gene id: 643561:ACAV_RS08335
uniprot id: F0Q5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS09580
gene id: 643561:ACAV_RS09580
uniprot id: F0Q853
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

643561:ACAV RS17795
gene id: 643561:ACAV_RS17795
uniprot id: F0QCK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

643561:ACAV RS20095
gene id: 643561:ACAV_RS20095
uniprot id: F0Q4B1
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

643561:ACAV RS17330
gene id: 643561:ACAV_RS17330
uniprot id: F0QBP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

643561:ACAV RS06280
gene id: 643561:ACAV_RS06280
uniprot id: F0Q0I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS06250
gene id: 643561:ACAV_RS06250
uniprot id: F0Q0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

643561:ACAV RS06155
gene id: 643561:ACAV_RS06155
uniprot id: F0Q0F6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

643561:ACAV RS02050
gene id: 643561:ACAV_RS02050
uniprot id: F0Q4H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

643561:ACAV RS04275
gene id: 643561:ACAV_RS04275
uniprot id: F0Q9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS03845
gene id: 643561:ACAV_RS03845
uniprot id: F0Q8P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

643561:ACAV RS06585
gene id: 643561:ACAV_RS06585
uniprot id: F0Q1B8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS04545
gene id: 643561:ACAV_RS04545
uniprot id: F0QAC1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

643561:ACAV RS22080
gene id: 643561:ACAV_RS22080
uniprot id: F0Q8L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

643561:ACAV RS02450
gene id: 643561:ACAV_RS02450
uniprot id: F0Q5C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

643561:ACAV RS20650
gene id: 643561:ACAV_RS20650
uniprot id: F0Q5X2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

643561:ACAV RS08760
gene id: 643561:ACAV_RS08760
uniprot id: F0Q6D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

643561:ACAV RS21035
gene id: 643561:ACAV_RS21035
uniprot id: F0Q6S1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS21195
gene id: 643561:ACAV_RS21195
uniprot id: F0Q6U8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

643561:ACAV RS08445
gene id: 643561:ACAV_RS08445
uniprot id: F0Q5K0
names: Similarity
messages: Belongs to the peptidase S33 family.

643561:ACAV RS21685
gene id: 643561:ACAV_RS21685
uniprot id: F0Q7S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

643561:ACAV RS01195
gene id: 643561:ACAV_RS01195
uniprot id: F0Q2R1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS11125
gene id: 643561:ACAV_RS11125
uniprot id: F0QBK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS10175
gene id: 643561:ACAV_RS10175
uniprot id: F0Q9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

643561:ACAV RS20485
gene id: 643561:ACAV_RS20485
uniprot id: F0Q564
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS09045
gene id: 643561:ACAV_RS09045
uniprot id: F0Q765
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

643561:ACAV RS08565
gene id: 643561:ACAV_RS08565
uniprot id: F0Q5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

643561:ACAV RS20700
gene id: 643561:ACAV_RS20700
uniprot id: F0Q5Y2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

643561:ACAV RS18570
gene id: 643561:ACAV_RS18570
uniprot id: F0Q0X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

643561:ACAV RS23665
gene id: 643561:ACAV_RS23665
uniprot id: F0QCQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

643561:ACAV RS08870
gene id: 643561:ACAV_RS08870
uniprot id: F0Q6F8
names: Similarity
messages: Belongs to the UPF0234 family.

643561:ACAV RS04155
gene id: 643561:ACAV_RS04155
uniprot id: F0Q9G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

643561:ACAV RS17790
gene id: 643561:ACAV_RS17790
uniprot id: F0QCK8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

643561:ACAV RS20300
gene id: 643561:ACAV_RS20300
uniprot id: F0Q526
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

643561:ACAV RS07995
gene id: 643561:ACAV_RS07995
uniprot id: F0Q4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

643561:ACAV RS22625
gene id: 643561:ACAV_RS22625
uniprot id: F0QA66
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS12870
gene id: 643561:ACAV_RS12870
uniprot id: F0Q1I8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS04895
gene id: 643561:ACAV_RS04895
uniprot id: F0QB62
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

643561:ACAV RS05835
gene id: 643561:ACAV_RS05835
uniprot id: F0QCX3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

643561:ACAV RS00390
gene id: 643561:ACAV_RS00390
uniprot id: F0Q0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

643561:ACAV RS17515
gene id: 643561:ACAV_RS17515
uniprot id: F0QBS7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

643561:ACAV RS19860
gene id: 643561:ACAV_RS19860
uniprot id: F0Q464
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS02895
gene id: 643561:ACAV_RS02895
uniprot id: F0Q691
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

643561:ACAV RS11255
gene id: 643561:ACAV_RS11255
uniprot id: F0QCA0
names: Similarity
messages: Belongs to the peptidase S9C family.

643561:ACAV RS03650
gene id: 643561:ACAV_RS03650
uniprot id: F0Q7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS11035
gene id: 643561:ACAV_RS11035
uniprot id: F0QBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

643561:ACAV RS13155
gene id: 643561:ACAV_RS13155
uniprot id: F0Q2C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

643561:ACAV RS04740
gene id: 643561:ACAV_RS04740
uniprot id: F0QAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Homododecamer. Tetramer of trimer.
messages: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA.

643561:ACAV RS12990
gene id: 643561:ACAV_RS12990
uniprot id: F0Q1L2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS02825
gene id: 643561:ACAV_RS02825
uniprot id: F0Q676
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

643561:ACAV RS01555
gene id: 643561:ACAV_RS01555
uniprot id: F0Q3K2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS00335
gene id: 643561:ACAV_RS00335
uniprot id: F0Q0B1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

643561:ACAV RS04290
gene id: 643561:ACAV_RS04290
uniprot id: F0Q9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

643561:ACAV RS05225
gene id: 643561:ACAV_RS05225
uniprot id: F0QBD0
names: Similarity
messages: Belongs to the hyi family.

643561:ACAV RS15690
gene id: 643561:ACAV_RS15690
uniprot id: F0Q7J5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

643561:ACAV RS19985
gene id: 643561:ACAV_RS19985
uniprot id: F0Q489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

643561:ACAV RS04465
gene id: 643561:ACAV_RS04465
uniprot id: F0Q9N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

643561:ACAV RS01755
gene id: 643561:ACAV_RS01755
uniprot id: F0Q3P2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

643561:ACAV RS17810
gene id: 643561:ACAV_RS17810
uniprot id: F0QCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

643561:ACAV RS04600
gene id: 643561:ACAV_RS04600
uniprot id: F0QAD2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

643561:ACAV RS02020
gene id: 643561:ACAV_RS02020
uniprot id: F0Q4G8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

643561:ACAV RS21895
gene id: 643561:ACAV_RS21895
uniprot id: F0Q8I3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

643561:ACAV RS04560
gene id: 643561:ACAV_RS04560
uniprot id: F0QAC4
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS17775
gene id: 643561:ACAV_RS17775
uniprot id: F0QCK5
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

643561:ACAV RS14375
gene id: 643561:ACAV_RS14375
uniprot id: F0Q4W7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS03055
gene id: 643561:ACAV_RS03055
uniprot id: F0Q6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

643561:ACAV RS19715
gene id: 643561:ACAV_RS19715
uniprot id: F0Q3G3
names: Similarity
messages: Belongs to the TlyA family.

643561:ACAV RS17725
gene id: 643561:ACAV_RS17725
uniprot id: F0QCJ5
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS17125
gene id: 643561:ACAV_RS17125
uniprot id: F0QAX3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

643561:ACAV RS14640
gene id: 643561:ACAV_RS14640
uniprot id: F0Q5P4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS21495
gene id: 643561:ACAV_RS21495
uniprot id: F0Q7N4
names: Similarity
messages: Belongs to the PhzF family.

643561:ACAV RS08355
gene id: 643561:ACAV_RS08355
uniprot id: F0Q5I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

643561:ACAV RS22280
gene id: 643561:ACAV_RS22280
uniprot id: F0Q9B9
names: Similarity
messages: Belongs to the thioredoxin family.

643561:ACAV RS07535
gene id: 643561:ACAV_RS07535
uniprot id: F0Q3S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

643561:ACAV RS01395
gene id: 643561:ACAV_RS01395
uniprot id: F0Q2V0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

643561:ACAV RS20030
gene id: 643561:ACAV_RS20030
uniprot id: F0Q498
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS10685
gene id: 643561:ACAV_RS10685
uniprot id: F0QAN4
names: Similarity
messages: Belongs to the P(II) protein family.

643561:ACAV RS14080
gene id: 643561:ACAV_RS14080
uniprot id: F0Q438
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

643561:ACAV RS05915
gene id: 643561:ACAV_RS05915
uniprot id: F0QCY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

643561:ACAV RS12850
gene id: 643561:ACAV_RS12850
uniprot id: F0Q1I4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS10920
gene id: 643561:ACAV_RS10920
uniprot id: F0QBF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

643561:ACAV RS12420
gene id: 643561:ACAV_RS12420
uniprot id: F0Q0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

643561:ACAV RS14335
gene id: 643561:ACAV_RS14335
uniprot id: F0Q4V9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS02345
gene id: 643561:ACAV_RS02345
uniprot id: F0Q5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

643561:ACAV RS07870
gene id: 643561:ACAV_RS07870
uniprot id: F0Q4L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS14560
gene id: 643561:ACAV_RS14560
uniprot id: F0Q504
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

643561:ACAV RS09225
gene id: 643561:ACAV_RS09225
uniprot id: F0Q7A3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS10600
gene id: 643561:ACAV_RS10600
uniprot id: F0QAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS08585
gene id: 643561:ACAV_RS08585
uniprot id: F0Q5M7
names: Similarity
messages: Belongs to the peptidase S58 family.

643561:ACAV RS18145
gene id: 643561:ACAV_RS18145
uniprot id: F0QDJ9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

643561:ACAV RS21590
gene id: 643561:ACAV_RS21590
uniprot id: F0Q7Q2
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS04450
gene id: 643561:ACAV_RS04450
uniprot id: F0Q9M8
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

643561:ACAV RS20455
gene id: 643561:ACAV_RS20455
uniprot id: F0Q558
names: Similarity
messages: Belongs to the PhoH family.

643561:ACAV RS01715
gene id: 643561:ACAV_RS01715
uniprot id: F0Q3N4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

643561:ACAV RS03965
gene id: 643561:ACAV_RS03965
uniprot id: F0Q8R9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS00945
gene id: 643561:ACAV_RS00945
uniprot id: F0Q1Y9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS01920
gene id: 643561:ACAV_RS01920
uniprot id: F0Q4E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

643561:ACAV RS15715
gene id: 643561:ACAV_RS15715
uniprot id: F0Q7K0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

643561:ACAV RS12020
gene id: 643561:ACAV_RS12020
uniprot id: F0QD97
names: Function
names: Similarity
messages: Belongs to the nitrile hydratase subunit beta family.
messages: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

643561:ACAV RS22095
gene id: 643561:ACAV_RS22095
uniprot id: F0Q991
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

643561:ACAV RS04715
gene id: 643561:ACAV_RS04715
uniprot id: F0QAF5
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

643561:ACAV RS15660
gene id: 643561:ACAV_RS15660
uniprot id: F0Q7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

643561:ACAV RS17460
gene id: 643561:ACAV_RS17460
uniprot id: F0QBR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

643561:ACAV RS11080
gene id: 643561:ACAV_RS11080
uniprot id: F0QBJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS05805
gene id: 643561:ACAV_RS05805
uniprot id: F0QCW7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

643561:ACAV RS11855
gene id: 643561:ACAV_RS11855
uniprot id: F0QD64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

643561:ACAV RS19890
gene id: 643561:ACAV_RS19890
uniprot id: F0Q470
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19685
gene id: 643561:ACAV_RS19685
uniprot id: F0Q3F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

643561:ACAV RS10665
gene id: 643561:ACAV_RS10665
uniprot id: F0QAN0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

643561:ACAV RS22580
gene id: 643561:ACAV_RS22580
uniprot id: F0QA56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS17815
gene id: 643561:ACAV_RS17815
uniprot id: F0QCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

643561:ACAV RS20865
gene id: 643561:ACAV_RS20865
uniprot id: F0Q613
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS21420
gene id: 643561:ACAV_RS21420
uniprot id: F0Q7L9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

643561:ACAV RS05580
gene id: 643561:ACAV_RS05580
uniprot id: F0QC77
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643561:ACAV RS05930
gene id: 643561:ACAV_RS05930
uniprot id: F0QCZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS09730
gene id: 643561:ACAV_RS09730
uniprot id: F0Q8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

643561:ACAV RS02425
gene id: 643561:ACAV_RS02425
uniprot id: F0Q5C3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS10400
gene id: 643561:ACAV_RS10400
uniprot id: F0Q9V2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

643561:ACAV RS20245
gene id: 643561:ACAV_RS20245
uniprot id: F0Q515
names: Similarity
messages: Belongs to the thioredoxin family.

643561:ACAV RS13275
gene id: 643561:ACAV_RS13275
uniprot id: F0Q2E4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643561:ACAV RS17120
gene id: 643561:ACAV_RS17120
uniprot id: F0QAX2
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

643561:ACAV RS08755
gene id: 643561:ACAV_RS08755
uniprot id: F0Q6D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

643561:ACAV RS21075
gene id: 643561:ACAV_RS21075
uniprot id: F0Q6S9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS18775
gene id: 643561:ACAV_RS18775
uniprot id: F0Q1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS21870
gene id: 643561:ACAV_RS21870
uniprot id: F0Q8H8
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

643561:ACAV RS09210
gene id: 643561:ACAV_RS09210
uniprot id: F0Q7A0
names: Similarity
messages: Belongs to the UPF0053 family.

643561:ACAV RS20260
gene id: 643561:ACAV_RS20260
uniprot id: F0Q518
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

643561:ACAV RS20510
gene id: 643561:ACAV_RS20510
uniprot id: F0Q569
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

643561:ACAV RS20705
gene id: 643561:ACAV_RS20705
uniprot id: F0Q5Y3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

643561:ACAV RS19000
gene id: 643561:ACAV_RS19000
uniprot id: F0Q1T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS02880
gene id: 643561:ACAV_RS02880
uniprot id: F0Q687
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

643561:ACAV RS20995
gene id: 643561:ACAV_RS20995
uniprot id: F0Q6R2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS12230
gene id: 643561:ACAV_RS12230
uniprot id: F0QDE0
names: Similarity
messages: Belongs to the citrate synthase family.

643561:ACAV RS10455
gene id: 643561:ACAV_RS10455
uniprot id: F0QAI8
names: Similarity
messages: Belongs to the GcvT family.

643561:ACAV RS18830
gene id: 643561:ACAV_RS18830
uniprot id: F0Q1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

643561:ACAV RS12395
gene id: 643561:ACAV_RS12395
uniprot id: F0Q0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS02860
gene id: 643561:ACAV_RS02860
uniprot id: F0Q683
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

643561:ACAV RS11240
gene id: 643561:ACAV_RS11240
uniprot id: F0QC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

643561:ACAV RS03955
gene id: 643561:ACAV_RS03955
uniprot id: F0Q8R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS21865
gene id: 643561:ACAV_RS21865
uniprot id: F0Q8H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS12060
gene id: 643561:ACAV_RS12060
uniprot id: F0QDA5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

643561:ACAV RS09830
gene id: 643561:ACAV_RS09830
uniprot id: F0Q8X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS22005
gene id: 643561:ACAV_RS22005
uniprot id: F0Q8K5
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

643561:ACAV RS15710
gene id: 643561:ACAV_RS15710
uniprot id: F0Q7J9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

643561:ACAV RS23220
gene id: 643561:ACAV_RS23220
uniprot id: F0QBU0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

643561:ACAV RS23020
gene id: 643561:ACAV_RS23020
uniprot id: F0QB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS12750
gene id: 643561:ACAV_RS12750
uniprot id: F0Q1G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

643561:ACAV RS02650
gene id: 643561:ACAV_RS02650
uniprot id: F0Q640
names: Similarity
messages: Belongs to the transglycosylase Slt family.

643561:ACAV RS00855
gene id: 643561:ACAV_RS00855
uniprot id: F0Q1X1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

643561:ACAV RS15820
gene id: 643561:ACAV_RS15820
uniprot id: F0Q897
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

643561:ACAV RS15445
gene id: 643561:ACAV_RS15445
uniprot id: F0Q7E5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS18580
gene id: 643561:ACAV_RS18580
uniprot id: F0Q0X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS03010
gene id: 643561:ACAV_RS03010
uniprot id: F0Q6Y2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

643561:ACAV RS22545
gene id: 643561:ACAV_RS22545
uniprot id: F0QA49
names: Similarity
messages: Belongs to the pirin family.

643561:ACAV RS13905
gene id: 643561:ACAV_RS13905
uniprot id: F0Q403
names: Similarity
messages: Belongs to the aspartokinase family.

643561:ACAV RS16210
gene id: 643561:ACAV_RS16210
uniprot id: F0Q942
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

643561:ACAV RS14345
gene id: 643561:ACAV_RS14345
uniprot id: F0Q4W1
names: Similarity
messages: Belongs to the DapA family.

643561:ACAV RS08600
gene id: 643561:ACAV_RS08600
uniprot id: F0Q5N0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

643561:ACAV RS02415
gene id: 643561:ACAV_RS02415
uniprot id: F0Q5C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS16880
gene id: 643561:ACAV_RS16880
uniprot id: F0QAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS02230
gene id: 643561:ACAV_RS02230
uniprot id: F0Q4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS01375
gene id: 643561:ACAV_RS01375
uniprot id: F0Q2U6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS17420
gene id: 643561:ACAV_RS17420
uniprot id: F0QBQ9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

643561:ACAV RS17945
gene id: 643561:ACAV_RS17945
uniprot id: F0QDG0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS11235
gene id: 643561:ACAV_RS11235
uniprot id: F0QC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643561:ACAV RS11030
gene id: 643561:ACAV_RS11030
uniprot id: F0QBI1
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

643561:ACAV RS02315
gene id: 643561:ACAV_RS02315
uniprot id: F0Q5A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

643561:ACAV RS15375
gene id: 643561:ACAV_RS15375
uniprot id: F0Q7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS06960
gene id: 643561:ACAV_RS06960
uniprot id: F0Q272
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

643561:ACAV RS17245
gene id: 643561:ACAV_RS17245
uniprot id: F0QBM6
names: Similarity
messages: Belongs to the CFA/CMAS family.

643561:ACAV RS23085
gene id: 643561:ACAV_RS23085
uniprot id: F0QB35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS04175
gene id: 643561:ACAV_RS04175
uniprot id: F0Q9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

643561:ACAV RS01685
gene id: 643561:ACAV_RS01685
uniprot id: F0Q3M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

643561:ACAV RS09910
gene id: 643561:ACAV_RS09910
uniprot id: F0Q8Y5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

643561:ACAV RS04170
gene id: 643561:ACAV_RS04170
uniprot id: F0Q9H2
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

643561:ACAV RS18040
gene id: 643561:ACAV_RS18040
uniprot id: F0QDH8
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

643561:ACAV RS03625
gene id: 643561:ACAV_RS03625
uniprot id: F0Q7Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

643561:ACAV RS20635
gene id: 643561:ACAV_RS20635
uniprot id: F0Q5W9
names: Similarity
messages: Belongs to the YciI family.

643561:ACAV RS07365
gene id: 643561:ACAV_RS07365
uniprot id: F0Q316
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

643561:ACAV RS22255
gene id: 643561:ACAV_RS22255
uniprot id: F0Q9B4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

643561:ACAV RS22070
gene id: 643561:ACAV_RS22070
uniprot id: F0Q8L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643561:ACAV RS07610
gene id: 643561:ACAV_RS07610
uniprot id: F0Q3T7
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

643561:ACAV RS15465
gene id: 643561:ACAV_RS15465
uniprot id: F0Q7E9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS10440
gene id: 643561:ACAV_RS10440
uniprot id: F0QAI5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

643561:ACAV RS04855
gene id: 643561:ACAV_RS04855
uniprot id: F0QB54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS18835
gene id: 643561:ACAV_RS18835
uniprot id: F0Q1Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

643561:ACAV RS19605
gene id: 643561:ACAV_RS19605
uniprot id: F0Q3E1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS11705
gene id: 643561:ACAV_RS11705
uniprot id: F0QD34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS07575
gene id: 643561:ACAV_RS07575
uniprot id: F0Q3S9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643561:ACAV RS17680
gene id: 643561:ACAV_RS17680
uniprot id: F0QCI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS15230
gene id: 643561:ACAV_RS15230
uniprot id: F0Q6M8
names: Similarity
messages: Belongs to the DSD1 family.

643561:ACAV RS16130
gene id: 643561:ACAV_RS16130
uniprot id: F0Q927
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

643561:ACAV RS04880
gene id: 643561:ACAV_RS04880
uniprot id: F0QB59
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS13090
gene id: 643561:ACAV_RS13090
uniprot id: F0Q2A9
names: Similarity
messages: Belongs to the UPF0434 family.

643561:ACAV RS22435
gene id: 643561:ACAV_RS22435
uniprot id: F0Q9F0
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

643561:ACAV RS17825
gene id: 643561:ACAV_RS17825
uniprot id: F0QCL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

643561:ACAV RS14880
gene id: 643561:ACAV_RS14880
uniprot id: F0Q5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS14065
gene id: 643561:ACAV_RS14065
uniprot id: F0Q435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS14855
gene id: 643561:ACAV_RS14855
uniprot id: F0Q5T8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

643561:ACAV RS18510
gene id: 643561:ACAV_RS18510
uniprot id: F0Q0W0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS13725
gene id: 643561:ACAV_RS13725
uniprot id: F0Q394
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

643561:ACAV RS03600
gene id: 643561:ACAV_RS03600
uniprot id: F0Q7X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

643561:ACAV RS12560
gene id: 643561:ACAV_RS12560
uniprot id: F0Q0P9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS15135
gene id: 643561:ACAV_RS15135
uniprot id: F0Q6K9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

643561:ACAV RS12830
gene id: 643561:ACAV_RS12830
uniprot id: F0Q1I0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

643561:ACAV RS03295
gene id: 643561:ACAV_RS03295
uniprot id: F0Q741
names: Similarity
messages: Belongs to the pirin family.

643561:ACAV RS15420
gene id: 643561:ACAV_RS15420
uniprot id: F0Q7E0
names: Similarity
messages: Belongs to the VgrG protein family.

643561:ACAV RS01730
gene id: 643561:ACAV_RS01730
uniprot id: F0Q3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

643561:ACAV RS21460
gene id: 643561:ACAV_RS21460
uniprot id: F0Q7M7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

643561:ACAV RS23190
gene id: 643561:ACAV_RS23190
uniprot id: F0QBT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

643561:ACAV RS20435
gene id: 643561:ACAV_RS20435
uniprot id: F0Q554
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

643561:ACAV RS18125
gene id: 643561:ACAV_RS18125
uniprot id: F0QDJ5
names: Function
names: Similarity
messages: Belongs to the ADC family.
messages: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.

643561:ACAV RS05920
gene id: 643561:ACAV_RS05920
uniprot id: F0QCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS12050
gene id: 643561:ACAV_RS12050
uniprot id: F0QDA3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643561:ACAV RS22875
gene id: 643561:ACAV_RS22875
uniprot id: F0QAZ0
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

643561:ACAV RS10720
gene id: 643561:ACAV_RS10720
uniprot id: F0QAP2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

643561:ACAV RS02955
gene id: 643561:ACAV_RS02955
uniprot id: F0Q6A2
names: Similarity
messages: Belongs to the GSP E family.

643561:ACAV RS18195
gene id: 643561:ACAV_RS18195
uniprot id: F0QDK9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

643561:ACAV RS09875
gene id: 643561:ACAV_RS09875
uniprot id: F0Q8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS10160
gene id: 643561:ACAV_RS10160
uniprot id: F0Q9Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

643561:ACAV RS20820
gene id: 643561:ACAV_RS20820
uniprot id: F0Q604
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS20250
gene id: 643561:ACAV_RS20250
uniprot id: F0Q516
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

643561:ACAV RS14495
gene id: 643561:ACAV_RS14495
uniprot id: F0Q4Z1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS08615
gene id: 643561:ACAV_RS08615
uniprot id: F0Q5N3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS11620
gene id: 643561:ACAV_RS11620
uniprot id: F0QD17
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

643561:ACAV RS02305
gene id: 643561:ACAV_RS02305
uniprot id: F0Q599
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS00260
gene id: 643561:ACAV_RS00260
uniprot id: F0Q096
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS21390
gene id: 643561:ACAV_RS21390
uniprot id: F0Q7L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

643561:ACAV RS21330
gene id: 643561:ACAV_RS21330
uniprot id: F0Q6X5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

643561:ACAV RS02875
gene id: 643561:ACAV_RS02875
uniprot id: F0Q686
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

643561:ACAV RS12405
gene id: 643561:ACAV_RS12405
uniprot id: F0Q0L8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS02065
gene id: 643561:ACAV_RS02065
uniprot id: F0Q4H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

643561:ACAV RS08660
gene id: 643561:ACAV_RS08660
uniprot id: F0Q6B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643561:ACAV RS22450
gene id: 643561:ACAV_RS22450
uniprot id: F0Q9F3
names: Similarity
messages: Belongs to the transketolase family.

643561:ACAV RS00820
gene id: 643561:ACAV_RS00820
uniprot id: F0Q1W3
names: Similarity
messages: Belongs to the universal stress protein A family.

643561:ACAV RS03870
gene id: 643561:ACAV_RS03870
uniprot id: F0Q8Q1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

643561:ACAV RS11775
gene id: 643561:ACAV_RS11775
uniprot id: F0QD48
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS07060
gene id: 643561:ACAV_RS07060
uniprot id: F0Q293
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS11260
gene id: 643561:ACAV_RS11260
uniprot id: F0QCA1
names: Similarity
messages: Belongs to the thioredoxin family.

643561:ACAV RS12785
gene id: 643561:ACAV_RS12785
uniprot id: F0Q1H1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

643561:ACAV RS03680
gene id: 643561:ACAV_RS03680
uniprot id: F0Q7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

643561:ACAV RS11190
gene id: 643561:ACAV_RS11190
uniprot id: F0QC87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

643561:ACAV RS11955
gene id: 643561:ACAV_RS11955
uniprot id: F0QD84
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

643561:ACAV RS02500
gene id: 643561:ACAV_RS02500
uniprot id: F0Q5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

643561:ACAV RS04850
gene id: 643561:ACAV_RS04850
uniprot id: F0QAI2
names: Similarity
messages: Belongs to the BolA/IbaG family.

643561:ACAV RS17405
gene id: 643561:ACAV_RS17405
uniprot id: F0QBQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS00015
gene id: 643561:ACAV_RS00015
uniprot id: F0Q047
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

643561:ACAV RS08280
gene id: 643561:ACAV_RS08280
uniprot id: F0Q5G9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

643561:ACAV RS01130
gene id: 643561:ACAV_RS01130
uniprot id: F0Q226
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS01735
gene id: 643561:ACAV_RS01735
uniprot id: F0Q3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

643561:ACAV RS10385
gene id: 643561:ACAV_RS10385
uniprot id: F0Q9U9
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

643561:ACAV RS09615
gene id: 643561:ACAV_RS09615
uniprot id: F0Q860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

643561:ACAV RS19550
gene id: 643561:ACAV_RS19550
uniprot id: F0Q3D0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS03865
gene id: 643561:ACAV_RS03865
uniprot id: F0Q8Q0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

643561:ACAV RS21355
gene id: 643561:ACAV_RS21355
uniprot id: F0Q7K6
names: Similarity
messages: Belongs to the MotB family.

643561:ACAV RS08050
gene id: 643561:ACAV_RS08050
uniprot id: F0Q4Q0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS13270
gene id: 643561:ACAV_RS13270
uniprot id: F0Q2E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

643561:ACAV RS06100
gene id: 643561:ACAV_RS06100
uniprot id: F0Q0E5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

643561:ACAV RS19220
gene id: 643561:ACAV_RS19220
uniprot id: F0Q2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS14820
gene id: 643561:ACAV_RS14820
uniprot id: F0Q5T1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS05570
gene id: 643561:ACAV_RS05570
uniprot id: F0QC75
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS16280
gene id: 643561:ACAV_RS16280
uniprot id: F0Q956
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19540
gene id: 643561:ACAV_RS19540
uniprot id: F0Q3C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

643561:ACAV RS12910
gene id: 643561:ACAV_RS12910
uniprot id: F0Q1J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS20805
gene id: 643561:ACAV_RS20805
uniprot id: F0Q601
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

643561:ACAV RS17745
gene id: 643561:ACAV_RS17745
uniprot id: F0QCJ9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

643561:ACAV RS01760
gene id: 643561:ACAV_RS01760
uniprot id: F0Q3P3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

643561:ACAV RS20745
gene id: 643561:ACAV_RS20745
uniprot id: F0Q5Z1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643561:ACAV RS08925
gene id: 643561:ACAV_RS08925
uniprot id: F0Q6G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS16760
gene id: 643561:ACAV_RS16760
uniprot id: F0QA24
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS07290
gene id: 643561:ACAV_RS07290
uniprot id: F0Q304
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

643561:ACAV RS08030
gene id: 643561:ACAV_RS08030
uniprot id: F0Q4P6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS07395
gene id: 643561:ACAV_RS07395
uniprot id: F0Q321
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS20925
gene id: 643561:ACAV_RS20925
uniprot id: F0Q625
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

643561:ACAV RS10995
gene id: 643561:ACAV_RS10995
uniprot id: F0QBH4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

643561:ACAV RS21185
gene id: 643561:ACAV_RS21185
uniprot id: F0Q6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

643561:ACAV RS07315
gene id: 643561:ACAV_RS07315
uniprot id: F0Q309
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS06315
gene id: 643561:ACAV_RS06315
uniprot id: F0Q0I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS04335
gene id: 643561:ACAV_RS04335
uniprot id: F0Q9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS13735
gene id: 643561:ACAV_RS13735
uniprot id: F0Q396
names: Similarity
messages: Belongs to the HesB/IscA family.

643561:ACAV RS09725
gene id: 643561:ACAV_RS09725
uniprot id: F0Q8U9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643561:ACAV RS10755
gene id: 643561:ACAV_RS10755
uniprot id: F0QAP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

643561:ACAV RS19545
gene id: 643561:ACAV_RS19545
uniprot id: F0Q3C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell inner membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

643561:ACAV RS20735
gene id: 643561:ACAV_RS20735
uniprot id: F0Q5Y9
names: Similarity
messages: Belongs to the OprB family.

643561:ACAV RS14020
gene id: 643561:ACAV_RS14020
uniprot id: F0Q426
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

643561:ACAV RS13630
gene id: 643561:ACAV_RS13630
uniprot id: F0Q377
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

643561:ACAV RS04535
gene id: 643561:ACAV_RS04535
uniprot id: F0QAB9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS09195
gene id: 643561:ACAV_RS09195
uniprot id: F0Q797
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

643561:ACAV RS20540
gene id: 643561:ACAV_RS20540
uniprot id: F0Q575
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

643561:ACAV RS22195
gene id: 643561:ACAV_RS22195
uniprot id: F0Q9A2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

643561:ACAV RS13755
gene id: 643561:ACAV_RS13755
uniprot id: F0Q3A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

643561:ACAV RS09355
gene id: 643561:ACAV_RS09355
uniprot id: F0Q807
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS13545
gene id: 643561:ACAV_RS13545
uniprot id: F0Q360
names: Subcellular Location Annotation
messages: Cytoplasm

643561:ACAV RS12685
gene id: 643561:ACAV_RS12685
uniprot id: F0Q0S5
names: Similarity
messages: Belongs to the thioredoxin family.

643561:ACAV RS05760
gene id: 643561:ACAV_RS05760
uniprot id: F0QCV8
names: Similarity
messages: Belongs to the MQO family.

643561:ACAV RS01595
gene id: 643561:ACAV_RS01595
uniprot id: F0Q3L0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS16335
gene id: 643561:ACAV_RS16335
uniprot id: F0Q967
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS17500
gene id: 643561:ACAV_RS17500
uniprot id: F0QBS4
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

643561:ACAV RS11865
gene id: 643561:ACAV_RS11865
uniprot id: F0QD66
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS12455
gene id: 643561:ACAV_RS12455
uniprot id: F0Q0M8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

643561:ACAV RS21770
gene id: 643561:ACAV_RS21770
uniprot id: F0Q8F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS01050
gene id: 643561:ACAV_RS01050
uniprot id: F0Q210
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

643561:ACAV RS03090
gene id: 643561:ACAV_RS03090
uniprot id: F0Q6Z9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

643561:ACAV RS06055
gene id: 643561:ACAV_RS06055
uniprot id: F0Q0D6
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

643561:ACAV RS13230
gene id: 643561:ACAV_RS13230
uniprot id: F0Q2D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS00830
gene id: 643561:ACAV_RS00830
uniprot id: F0Q1W5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS02780
gene id: 643561:ACAV_RS02780
uniprot id: F0Q667
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

643561:ACAV RS08900
gene id: 643561:ACAV_RS08900
uniprot id: F0Q6G4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

643561:ACAV RS06530
gene id: 643561:ACAV_RS06530
uniprot id: F0Q1A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS08420
gene id: 643561:ACAV_RS08420
uniprot id: F0Q5J5
names: Similarity
messages: Belongs to the TPP enzyme family.

643561:ACAV RS23225
gene id: 643561:ACAV_RS23225
uniprot id: F0QBU1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS04410
gene id: 643561:ACAV_RS04410
uniprot id: F0Q9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS06395
gene id: 643561:ACAV_RS06395
uniprot id: F0Q180
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

643561:ACAV RS01340
gene id: 643561:ACAV_RS01340
uniprot id: F0Q2T9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS04035
gene id: 643561:ACAV_RS04035
uniprot id: F0Q8T3
names: Similarity
messages: Belongs to the SsuE family.

643561:ACAV RS08130
gene id: 643561:ACAV_RS08130
uniprot id: F0Q4R3
names: Similarity
messages: Belongs to the peptidase C56 family.

643561:ACAV RS04750
gene id: 643561:ACAV_RS04750
uniprot id: F0QAG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS17770
gene id: 643561:ACAV_RS17770
uniprot id: F0QCK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS05880
gene id: 643561:ACAV_RS05880
uniprot id: F0QCY2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS06895
gene id: 643561:ACAV_RS06895
uniprot id: F0Q258
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

643561:ACAV RS21040
gene id: 643561:ACAV_RS21040
uniprot id: F0Q6S2
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

643561:ACAV RS04115
gene id: 643561:ACAV_RS04115
uniprot id: F0Q9G0
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

643561:ACAV RS07665
gene id: 643561:ACAV_RS07665
uniprot id: F0Q3U9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS16325
gene id: 643561:ACAV_RS16325
uniprot id: F0Q965
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

643561:ACAV RS21565
gene id: 643561:ACAV_RS21565
uniprot id: F0Q7P7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

643561:ACAV RS08745
gene id: 643561:ACAV_RS08745
uniprot id: F0Q6D4
names: Similarity
messages: Belongs to the skp family.

643561:ACAV RS13940
gene id: 643561:ACAV_RS13940
uniprot id: F0Q410
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

643561:ACAV RS00080
gene id: 643561:ACAV_RS00080
uniprot id: F0Q059
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

643561:ACAV RS03520
gene id: 643561:ACAV_RS03520
uniprot id: F0Q7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS17820
gene id: 643561:ACAV_RS17820
uniprot id: F0QCL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

643561:ACAV RS09375
gene id: 643561:ACAV_RS09375
uniprot id: F0Q811
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS18170
gene id: 643561:ACAV_RS18170
uniprot id: F0QDK4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS14675
gene id: 643561:ACAV_RS14675
uniprot id: F0Q5Q1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

643561:ACAV RS08000
gene id: 643561:ACAV_RS08000
uniprot id: F0Q4P0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

643561:ACAV RS20645
gene id: 643561:ACAV_RS20645
uniprot id: F0Q5X1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS15130
gene id: 643561:ACAV_RS15130
uniprot id: F0Q6K8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS11100
gene id: 643561:ACAV_RS11100
uniprot id: F0QBJ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

643561:ACAV RS07605
gene id: 643561:ACAV_RS07605
uniprot id: F0Q3T6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS10985
gene id: 643561:ACAV_RS10985
uniprot id: F0QBH2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

643561:ACAV RS06890
gene id: 643561:ACAV_RS06890
uniprot id: F0Q257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS08300
gene id: 643561:ACAV_RS08300
uniprot id: F0Q5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS02330
gene id: 643561:ACAV_RS02330
uniprot id: F0Q5A4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

643561:ACAV RS12205
gene id: 643561:ACAV_RS12205
uniprot id: F0QDD5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

643561:ACAV RS01410
gene id: 643561:ACAV_RS01410
uniprot id: F0Q2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS13035
gene id: 643561:ACAV_RS13035
uniprot id: F0Q1M1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS00880
gene id: 643561:ACAV_RS00880
uniprot id: F0Q1X6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS10000
gene id: 643561:ACAV_RS10000
uniprot id: F0Q903
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS16510
gene id: 643561:ACAV_RS16510
uniprot id: F0Q9X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

643561:ACAV RS02045
gene id: 643561:ACAV_RS02045
uniprot id: F0Q4H3
names: Subcellular Location Annotation
messages: Cytoplasm

643561:ACAV RS13350
gene id: 643561:ACAV_RS13350
uniprot id: F0Q2F5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

643561:ACAV RS23575
gene id: 643561:ACAV_RS23575
uniprot id: F0QCP1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

643561:ACAV RS14430
gene id: 643561:ACAV_RS14430
uniprot id: F0Q4X8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

643561:ACAV RS10735
gene id: 643561:ACAV_RS10735
uniprot id: F0QAP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

643561:ACAV RS14765
gene id: 643561:ACAV_RS14765
uniprot id: F0Q5S0
names: Similarity
messages: Belongs to the histone deacetylase family.

643561:ACAV RS04355
gene id: 643561:ACAV_RS04355
uniprot id: F0Q9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

643561:ACAV RS15360
gene id: 643561:ACAV_RS15360
uniprot id: F0Q6Q4
names: Similarity
messages: Belongs to the PrpD family.

643561:ACAV RS19035
gene id: 643561:ACAV_RS19035
uniprot id: F0Q1U0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643561:ACAV RS06305
gene id: 643561:ACAV_RS06305
uniprot id: F0Q0I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS19810
gene id: 643561:ACAV_RS19810
uniprot id: F0Q3I2
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS03735
gene id: 643561:ACAV_RS03735
uniprot id: F0Q8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS21765
gene id: 643561:ACAV_RS21765
uniprot id: F0Q8F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.
messages: Homotrimer.

643561:ACAV RS16120
gene id: 643561:ACAV_RS16120
uniprot id: F0Q925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS21055
gene id: 643561:ACAV_RS21055
uniprot id: F0Q6S5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

643561:ACAV RS05845
gene id: 643561:ACAV_RS05845
uniprot id: F0QCX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

643561:ACAV RS18390
gene id: 643561:ACAV_RS18390
uniprot id: F0Q0T7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

643561:ACAV RS04905
gene id: 643561:ACAV_RS04905
uniprot id: F0QB64
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

643561:ACAV RS08740
gene id: 643561:ACAV_RS08740
uniprot id: F0Q6D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

643561:ACAV RS23005
gene id: 643561:ACAV_RS23005
uniprot id: F0QB17
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS16555
gene id: 643561:ACAV_RS16555
uniprot id: F0Q9Y1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

643561:ACAV RS09835
gene id: 643561:ACAV_RS09835
uniprot id: F0Q8X1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS04125
gene id: 643561:ACAV_RS04125
uniprot id: F0Q9G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

643561:ACAV RS06245
gene id: 643561:ACAV_RS06245
uniprot id: F0Q0H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

643561:ACAV RS21980
gene id: 643561:ACAV_RS21980
uniprot id: F0Q8K0
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

643561:ACAV RS08765
gene id: 643561:ACAV_RS08765
uniprot id: F0Q6D8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

643561:ACAV RS10695
gene id: 643561:ACAV_RS10695
uniprot id: F0QAN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

643561:ACAV RS01305
gene id: 643561:ACAV_RS01305
uniprot id: F0Q2T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

643561:ACAV RS07835
gene id: 643561:ACAV_RS07835
uniprot id: F0Q3Y3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

643561:ACAV RS09070
gene id: 643561:ACAV_RS09070
uniprot id: F0Q770
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

643561:ACAV RS03375
gene id: 643561:ACAV_RS03375
uniprot id: F0Q7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS06570
gene id: 643561:ACAV_RS06570
uniprot id: F0Q1B5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

643561:ACAV RS10070
gene id: 643561:ACAV_RS10070
uniprot id: F0Q9N3
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS08060
gene id: 643561:ACAV_RS08060
uniprot id: F0Q4Q2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

643561:ACAV RS14930
gene id: 643561:ACAV_RS14930
uniprot id: F0Q5V3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS14040
gene id: 643561:ACAV_RS14040
uniprot id: F0Q430
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS04965
gene id: 643561:ACAV_RS04965
uniprot id: F0QB76
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS22200
gene id: 643561:ACAV_RS22200
uniprot id: F0Q9A3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS19990
gene id: 643561:ACAV_RS19990
uniprot id: F0Q490
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

643561:ACAV RS21255
gene id: 643561:ACAV_RS21255
uniprot id: F0Q6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

643561:ACAV RS08295
gene id: 643561:ACAV_RS08295
uniprot id: F0Q5H2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

643561:ACAV RS00235
gene id: 643561:ACAV_RS00235
uniprot id: F0Q089
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS01360
gene id: 643561:ACAV_RS01360
uniprot id: F0Q2U3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS13885
gene id: 643561:ACAV_RS13885
uniprot id: F0Q401
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

643561:ACAV RS02885
gene id: 643561:ACAV_RS02885
uniprot id: F0Q689
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

643561:ACAV RS04055
gene id: 643561:ACAV_RS04055
uniprot id: F0Q8T7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS22100
gene id: 643561:ACAV_RS22100
uniprot id: F0Q992
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS11010
gene id: 643561:ACAV_RS11010
uniprot id: F0QBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS08465
gene id: 643561:ACAV_RS08465
uniprot id: F0Q5K4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS22815
gene id: 643561:ACAV_RS22815
uniprot id: F0QAA5
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

643561:ACAV RS13190
gene id: 643561:ACAV_RS13190
uniprot id: F0Q2C9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS05855
gene id: 643561:ACAV_RS05855
uniprot id: F0QCX7
names: Similarity
messages: Belongs to the fabD family.

643561:ACAV RS12915
gene id: 643561:ACAV_RS12915
uniprot id: F0Q1J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS11830
gene id: 643561:ACAV_RS11830
uniprot id: F0QD59
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS05245
gene id: 643561:ACAV_RS05245
uniprot id: F0QC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS12190
gene id: 643561:ACAV_RS12190
uniprot id: F0QDD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS13535
gene id: 643561:ACAV_RS13535
uniprot id: F0Q358
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS14475
gene id: 643561:ACAV_RS14475
uniprot id: F0Q4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: Periplasm

643561:ACAV RS01300
gene id: 643561:ACAV_RS01300
uniprot id: F0Q2T1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

643561:ACAV RS17300
gene id: 643561:ACAV_RS17300
uniprot id: F0QBN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

643561:ACAV RS03660
gene id: 643561:ACAV_RS03660
uniprot id: F0Q7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

643561:ACAV RS09650
gene id: 643561:ACAV_RS09650
uniprot id: F0Q867
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

643561:ACAV RS14875
gene id: 643561:ACAV_RS14875
uniprot id: F0Q5U2
names: Similarity
messages: Belongs to the CmpA/NrtA family.

643561:ACAV RS21445
gene id: 643561:ACAV_RS21445
uniprot id: F0Q7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

643561:ACAV RS03265
gene id: 643561:ACAV_RS03265
uniprot id: F0Q735
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS19635
gene id: 643561:ACAV_RS19635
uniprot id: F0Q3E7
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS17625
gene id: 643561:ACAV_RS17625
uniprot id: F0QCH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS06385
gene id: 643561:ACAV_RS06385
uniprot id: F0Q178
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS14515
gene id: 643561:ACAV_RS14515
uniprot id: F0Q4Z5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS01695
gene id: 643561:ACAV_RS01695
uniprot id: F0Q3N0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

643561:ACAV RS01485
gene id: 643561:ACAV_RS01485
uniprot id: F0Q2X1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

643561:ACAV RS22165
gene id: 643561:ACAV_RS22165
uniprot id: F0Q996
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

643561:ACAV RS13075
gene id: 643561:ACAV_RS13075
uniprot id: F0Q2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

643561:ACAV RS17685
gene id: 643561:ACAV_RS17685
uniprot id: F0QCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

643561:ACAV RS22380
gene id: 643561:ACAV_RS22380
uniprot id: F0Q9D9
names: Similarity
messages: Belongs to the pyruvate kinase family.

643561:ACAV RS06260
gene id: 643561:ACAV_RS06260
uniprot id: F0Q0H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

643561:ACAV RS10165
gene id: 643561:ACAV_RS10165
uniprot id: F0Q9Q4
names: Similarity
messages: Belongs to the GARS family.

643561:ACAV RS04080
gene id: 643561:ACAV_RS04080
uniprot id: F0Q8U2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

643561:ACAV RS17840
gene id: 643561:ACAV_RS17840
uniprot id: F0QCL7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

643561:ACAV RS20840
gene id: 643561:ACAV_RS20840
uniprot id: F0Q608
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS09665
gene id: 643561:ACAV_RS09665
uniprot id: F0Q870
names: Similarity
messages: Belongs to the LOG family.

643561:ACAV RS22680
gene id: 643561:ACAV_RS22680
uniprot id: F0QA78
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS02270
gene id: 643561:ACAV_RS02270
uniprot id: F0Q592
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS05795
gene id: 643561:ACAV_RS05795
uniprot id: F0QCW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

643561:ACAV RS23015
gene id: 643561:ACAV_RS23015
uniprot id: F0QB21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS10885
gene id: 643561:ACAV_RS10885
uniprot id: F0QBF2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS15220
gene id: 643561:ACAV_RS15220
uniprot id: F0Q6M6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS08205
gene id: 643561:ACAV_RS08205
uniprot id: F0Q4S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell inner membrane

643561:ACAV RS16465
gene id: 643561:ACAV_RS16465
uniprot id: F0Q9W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

643561:ACAV RS02840
gene id: 643561:ACAV_RS02840
uniprot id: F0Q679
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

643561:ACAV RS05295
gene id: 643561:ACAV_RS05295
uniprot id: F0QC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

643561:ACAV RS19645
gene id: 643561:ACAV_RS19645
uniprot id: F0Q3E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS09795
gene id: 643561:ACAV_RS09795
uniprot id: F0Q8W3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS10320
gene id: 643561:ACAV_RS10320
uniprot id: F0Q9T6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS23745
gene id: 643561:ACAV_RS23745
uniprot id: F0QCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

643561:ACAV RS11130
gene id: 643561:ACAV_RS11130
uniprot id: F0QBK1
names: Similarity
messages: Belongs to the pirin family.

643561:ACAV RS02590
gene id: 643561:ACAV_RS02590
uniprot id: F0Q5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS07165
gene id: 643561:ACAV_RS07165
uniprot id: F0Q2Y4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS10145
gene id: 643561:ACAV_RS10145
uniprot id: F0Q9Q0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS22010
gene id: 643561:ACAV_RS22010
uniprot id: F0Q8K6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

643561:ACAV RS21260
gene id: 643561:ACAV_RS21260
uniprot id: F0Q6W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

643561:ACAV RS15730
gene id: 643561:ACAV_RS15730
uniprot id: F0Q7K3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

643561:ACAV RS10270
gene id: 643561:ACAV_RS10270
uniprot id: F0Q9S6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS02195
gene id: 643561:ACAV_RS02195
uniprot id: F0Q4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

643561:ACAV RS13880
gene id: 643561:ACAV_RS13880
uniprot id: F0Q400
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS05640
gene id: 643561:ACAV_RS05640
uniprot id: F0QCT3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS15540
gene id: 643561:ACAV_RS15540
uniprot id: F0Q7G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

643561:ACAV RS03260
gene id: 643561:ACAV_RS03260
uniprot id: F0Q734
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS14850
gene id: 643561:ACAV_RS14850
uniprot id: F0Q5T7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

643561:ACAV RS16250
gene id: 643561:ACAV_RS16250
uniprot id: F0Q950
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS16195
gene id: 643561:ACAV_RS16195
uniprot id: F0Q939
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

643561:ACAV RS15215
gene id: 643561:ACAV_RS15215
uniprot id: F0Q6M5
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

643561:ACAV RS04680
gene id: 643561:ACAV_RS04680
uniprot id: F0QAE8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS16400
gene id: 643561:ACAV_RS16400
uniprot id: F0Q980
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS10285
gene id: 643561:ACAV_RS10285
uniprot id: F0Q9S9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS01775
gene id: 643561:ACAV_RS01775
uniprot id: F0Q3P6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

643561:ACAV RS01275
gene id: 643561:ACAV_RS01275
uniprot id: F0Q2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS13145
gene id: 643561:ACAV_RS13145
uniprot id: F0Q2C0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS18840
gene id: 643561:ACAV_RS18840
uniprot id: F0Q1Q1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Periplasm
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

643561:ACAV RS16045
gene id: 643561:ACAV_RS16045
uniprot id: F0Q8E2
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

643561:ACAV RS07125
gene id: 643561:ACAV_RS07125
uniprot id: F0Q2X6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

643561:ACAV RS15395
gene id: 643561:ACAV_RS15395
uniprot id: F0Q7D4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

643561:ACAV RS10660
gene id: 643561:ACAV_RS10660
uniprot id: F0QAM9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

643561:ACAV RS20415
gene id: 643561:ACAV_RS20415
uniprot id: F0Q550
names: Similarity
messages: Belongs to the DSD1 family.

643561:ACAV RS11225
gene id: 643561:ACAV_RS11225
uniprot id: F0QC94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

643561:ACAV RS14760
gene id: 643561:ACAV_RS14760
uniprot id: F0Q5R9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS19560
gene id: 643561:ACAV_RS19560
uniprot id: F0Q3D2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS22075
gene id: 643561:ACAV_RS22075
uniprot id: F0Q8L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

643561:ACAV RS03635
gene id: 643561:ACAV_RS03635
uniprot id: F0Q7Y5
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

643561:ACAV RS13950
gene id: 643561:ACAV_RS13950
uniprot id: F0Q412
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS03975
gene id: 643561:ACAV_RS03975
uniprot id: F0Q8S1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS01910
gene id: 643561:ACAV_RS01910
uniprot id: F0Q4E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

643561:ACAV RS06075
gene id: 643561:ACAV_RS06075
uniprot id: F0Q0E0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

643561:ACAV RS09560
gene id: 643561:ACAV_RS09560
uniprot id: F0Q849
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

643561:ACAV RS12480
gene id: 643561:ACAV_RS12480
uniprot id: F0Q0N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

643561:ACAV RS02505
gene id: 643561:ACAV_RS02505
uniprot id: F0Q5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS14950
gene id: 643561:ACAV_RS14950
uniprot id: F0Q5V7
names: Similarity
messages: Belongs to the ketopantoate reductase family.

643561:ACAV RS05430
gene id: 643561:ACAV_RS05430
uniprot id: F0QC47
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

643561:ACAV RS21320
gene id: 643561:ACAV_RS21320
uniprot id: F0Q6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

643561:ACAV RS22270
gene id: 643561:ACAV_RS22270
uniprot id: F0Q9B7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

643561:ACAV RS08715
gene id: 643561:ACAV_RS08715
uniprot id: F0Q6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

643561:ACAV RS13540
gene id: 643561:ACAV_RS13540
uniprot id: F0Q359
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643561:ACAV RS11270
gene id: 643561:ACAV_RS11270
uniprot id: F0QCA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS07985
gene id: 643561:ACAV_RS07985
uniprot id: F0Q4N7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS13365
gene id: 643561:ACAV_RS13365
uniprot id: F0Q2F8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS19730
gene id: 643561:ACAV_RS19730
uniprot id: F0Q3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

643561:ACAV RS13675
gene id: 643561:ACAV_RS13675
uniprot id: F0Q386
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

643561:ACAV RS18520
gene id: 643561:ACAV_RS18520
uniprot id: F0Q0W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

643561:ACAV RS08710
gene id: 643561:ACAV_RS08710
uniprot id: F0Q6C7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS01520
gene id: 643561:ACAV_RS01520
uniprot id: F0Q3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS08875
gene id: 643561:ACAV_RS08875
uniprot id: F0Q6F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

643561:ACAV RS18515
gene id: 643561:ACAV_RS18515
uniprot id: F0Q0W1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS16260
gene id: 643561:ACAV_RS16260
uniprot id: F0Q952
names: Similarity
messages: Belongs to the UPF0111 family.

643561:ACAV RS17910
gene id: 643561:ACAV_RS17910
uniprot id: F0QCN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

643561:ACAV RS13745
gene id: 643561:ACAV_RS13745
uniprot id: F0Q398
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

643561:ACAV RS13440
gene id: 643561:ACAV_RS13440
uniprot id: F0Q2H5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

643561:ACAV RS22970
gene id: 643561:ACAV_RS22970
uniprot id: F0QB10
names: Similarity
messages: Belongs to the DprA/Smf family.

643561:ACAV RS01440
gene id: 643561:ACAV_RS01440
uniprot id: F0Q2W2
names: Similarity
messages: Belongs to the VgrG protein family.

643561:ACAV RS06380
gene id: 643561:ACAV_RS06380
uniprot id: F0Q0K0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS09235
gene id: 643561:ACAV_RS09235
uniprot id: F0Q7A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

643561:ACAV RS20100
gene id: 643561:ACAV_RS20100
uniprot id: F0Q4B2
names: Similarity
messages: Belongs to the asparaginase 1 family.

643561:ACAV RS06495
gene id: 643561:ACAV_RS06495
uniprot id: F0Q1A0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS08390
gene id: 643561:ACAV_RS08390
uniprot id: F0Q5I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

643561:ACAV RS14425
gene id: 643561:ACAV_RS14425
uniprot id: F0Q4X7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

643561:ACAV RS19580
gene id: 643561:ACAV_RS19580
uniprot id: F0Q3D6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS01980
gene id: 643561:ACAV_RS01980
uniprot id: F0Q4G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

643561:ACAV RS20015
gene id: 643561:ACAV_RS20015
uniprot id: F0Q495
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

643561:ACAV RS13080
gene id: 643561:ACAV_RS13080
uniprot id: F0Q2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643561:ACAV RS02520
gene id: 643561:ACAV_RS02520
uniprot id: F0Q5E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS11140
gene id: 643561:ACAV_RS11140
uniprot id: F0QBK3
names: Similarity
messages: Belongs to the pirin family.

643561:ACAV RS11025
gene id: 643561:ACAV_RS11025
uniprot id: F0QBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

643561:ACAV RS23250
gene id: 643561:ACAV_RS23250
uniprot id: F0QBU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS14240
gene id: 643561:ACAV_RS14240
uniprot id: F0Q4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

643561:ACAV RS06095
gene id: 643561:ACAV_RS06095
uniprot id: F0Q0E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

643561:ACAV RS18955
gene id: 643561:ACAV_RS18955
uniprot id: F0Q1S4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

643561:ACAV RS21400
gene id: 643561:ACAV_RS21400
uniprot id: F0Q7L5
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

643561:ACAV RS02110
gene id: 643561:ACAV_RS02110
uniprot id: F0Q4I7
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19185
gene id: 643561:ACAV_RS19185
uniprot id: F0Q2J3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

643561:ACAV RS12660
gene id: 643561:ACAV_RS12660
uniprot id: F0Q0S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

643561:ACAV RS01680
gene id: 643561:ACAV_RS01680
uniprot id: F0Q3M7
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

643561:ACAV RS18640
gene id: 643561:ACAV_RS18640
uniprot id: F0Q0Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

643561:ACAV RS00370
gene id: 643561:ACAV_RS00370
uniprot id: F0Q0B8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS05405
gene id: 643561:ACAV_RS05405
uniprot id: F0QC42
names: Similarity
messages: Belongs to the peptidase M20 family.

643561:ACAV RS15870
gene id: 643561:ACAV_RS15870
uniprot id: F0Q8A7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

643561:ACAV RS09935
gene id: 643561:ACAV_RS09935
uniprot id: F0Q8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

643561:ACAV RS06240
gene id: 643561:ACAV_RS06240
uniprot id: F0Q0H3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS06190
gene id: 643561:ACAV_RS06190
uniprot id: F0Q0G3
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

643561:ACAV RS05985
gene id: 643561:ACAV_RS05985
uniprot id: F0QD03
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

643561:ACAV RS10790
gene id: 643561:ACAV_RS10790
uniprot id: F0QAQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

643561:ACAV RS07865
gene id: 643561:ACAV_RS07865
uniprot id: F0Q3Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS05300
gene id: 643561:ACAV_RS05300
uniprot id: F0QC20
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS07370
gene id: 643561:ACAV_RS07370
uniprot id: F0Q317
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

643561:ACAV RS08730
gene id: 643561:ACAV_RS08730
uniprot id: F0Q6D1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS01035
gene id: 643561:ACAV_RS01035
uniprot id: F0Q207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS22245
gene id: 643561:ACAV_RS22245
uniprot id: F0Q9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

643561:ACAV RS02260
gene id: 643561:ACAV_RS02260
uniprot id: F0Q589
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19425
gene id: 643561:ACAV_RS19425
uniprot id: F0Q2P0
names: Similarity
messages: Belongs to the nitroreductase family.

643561:ACAV RS20000
gene id: 643561:ACAV_RS20000
uniprot id: F0Q492
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

643561:ACAV RS15225
gene id: 643561:ACAV_RS15225
uniprot id: F0Q6M7
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS11925
gene id: 643561:ACAV_RS11925
uniprot id: F0QD79
names: Similarity
messages: Belongs to the peptidase C40 family.

643561:ACAV RS07075
gene id: 643561:ACAV_RS07075
uniprot id: F0Q296
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

643561:ACAV RS16010
gene id: 643561:ACAV_RS16010
uniprot id: F0Q8D5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS13175
gene id: 643561:ACAV_RS13175
uniprot id: F0Q2C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

643561:ACAV RS18230
gene id: 643561:ACAV_RS18230
uniprot id: F0QDL4
names: Similarity
messages: Belongs to the peptidase M16 family.

643561:ACAV RS11055
gene id: 643561:ACAV_RS11055
uniprot id: F0QBI6
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

643561:ACAV RS11735
gene id: 643561:ACAV_RS11735
uniprot id: F0QD40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS22465
gene id: 643561:ACAV_RS22465
uniprot id: F0Q9F6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

643561:ACAV RS14660
gene id: 643561:ACAV_RS14660
uniprot id: F0Q5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS10410
gene id: 643561:ACAV_RS10410
uniprot id: F0Q9V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS11640
gene id: 643561:ACAV_RS11640
uniprot id: F0QD21
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS05610
gene id: 643561:ACAV_RS05610
uniprot id: F0QCS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

643561:ACAV RS19180
gene id: 643561:ACAV_RS19180
uniprot id: F0Q2J2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

643561:ACAV RS11450
gene id: 643561:ACAV_RS11450
uniprot id: F0QCD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS15590
gene id: 643561:ACAV_RS15590
uniprot id: F0Q7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

643561:ACAV RS03900
gene id: 643561:ACAV_RS03900
uniprot id: F0Q8Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

643561:ACAV RS16385
gene id: 643561:ACAV_RS16385
uniprot id: F0Q977
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

643561:ACAV RS01385
gene id: 643561:ACAV_RS01385
uniprot id: F0Q2U8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS17880
gene id: 643561:ACAV_RS17880
uniprot id: F0QCM4
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

643561:ACAV RS03670
gene id: 643561:ACAV_RS03670
uniprot id: F0Q7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

643561:ACAV RS09890
gene id: 643561:ACAV_RS09890
uniprot id: F0Q8Y1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS16945
gene id: 643561:ACAV_RS16945
uniprot id: F0QAT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

643561:ACAV RS18715
gene id: 643561:ACAV_RS18715
uniprot id: F0Q1M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

643561:ACAV RS02965
gene id: 643561:ACAV_RS02965
uniprot id: F0Q6A4
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

643561:ACAV RS04095
gene id: 643561:ACAV_RS04095
uniprot id: F0Q8U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

643561:ACAV RS04460
gene id: 643561:ACAV_RS04460
uniprot id: F0Q9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

643561:ACAV RS07570
gene id: 643561:ACAV_RS07570
uniprot id: F0Q3S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS08330
gene id: 643561:ACAV_RS08330
uniprot id: F0Q5H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS10545
gene id: 643561:ACAV_RS10545
uniprot id: F0QAK6
names: Similarity
messages: Belongs to the catalase family.

643561:ACAV RS07275
gene id: 643561:ACAV_RS07275
uniprot id: F0Q301
names: Similarity
messages: Belongs to the glutamine synthetase family.

643561:ACAV RS03610
gene id: 643561:ACAV_RS03610
uniprot id: F0Q7Y0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

643561:ACAV RS21210
gene id: 643561:ACAV_RS21210
uniprot id: F0Q6V1
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

643561:ACAV RS14135
gene id: 643561:ACAV_RS14135
uniprot id: F0Q448
names: Similarity
messages: Belongs to the AHA1 family.

643561:ACAV RS19450
gene id: 643561:ACAV_RS19450
uniprot id: F0Q2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

643561:ACAV RS21450
gene id: 643561:ACAV_RS21450
uniprot id: F0Q7M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

643561:ACAV RS00850
gene id: 643561:ACAV_RS00850
uniprot id: F0Q1W9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

643561:ACAV RS08770
gene id: 643561:ACAV_RS08770
uniprot id: F0Q6D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

643561:ACAV RS15560
gene id: 643561:ACAV_RS15560
uniprot id: F0Q7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS01825
gene id: 643561:ACAV_RS01825
uniprot id: F0Q3Q8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS15670
gene id: 643561:ACAV_RS15670
uniprot id: F0Q7J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

643561:ACAV RS21145
gene id: 643561:ACAV_RS21145
uniprot id: F0Q6U3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

643561:ACAV RS11290
gene id: 643561:ACAV_RS11290
uniprot id: F0QCA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS15905
gene id: 643561:ACAV_RS15905
uniprot id: F0Q8B4
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

643561:ACAV RS14740
gene id: 643561:ACAV_RS14740
uniprot id: F0Q5R4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS07700
gene id: 643561:ACAV_RS07700
uniprot id: F0Q3V6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

643561:ACAV RS17740
gene id: 643561:ACAV_RS17740
uniprot id: F0QCJ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

643561:ACAV RS21200
gene id: 643561:ACAV_RS21200
uniprot id: F0Q6U9
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

643561:ACAV RS17695
gene id: 643561:ACAV_RS17695
uniprot id: F0QCI9
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

643561:ACAV RS13795
gene id: 643561:ACAV_RS13795
uniprot id: F0Q3A7
names: Similarity
messages: Belongs to the IMPACT family.

643561:ACAV RS08970
gene id: 643561:ACAV_RS08970
uniprot id: F0Q6H2
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS08405
gene id: 643561:ACAV_RS08405
uniprot id: F0Q5J2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

643561:ACAV RS01270
gene id: 643561:ACAV_RS01270
uniprot id: F0Q2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS10190
gene id: 643561:ACAV_RS10190
uniprot id: F0Q9Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

643561:ACAV RS16235
gene id: 643561:ACAV_RS16235
uniprot id: F0Q947
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

643561:ACAV RS14435
gene id: 643561:ACAV_RS14435
uniprot id: F0Q4X9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS16320
gene id: 643561:ACAV_RS16320
uniprot id: F0Q964
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

643561:ACAV RS00840
gene id: 643561:ACAV_RS00840
uniprot id: F0Q1W7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS21135
gene id: 643561:ACAV_RS21135
uniprot id: F0Q6U1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643561:ACAV RS04910
gene id: 643561:ACAV_RS04910
uniprot id: F0QB65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

643561:ACAV RS03760
gene id: 643561:ACAV_RS03760
uniprot id: F0Q8M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

643561:ACAV RS18595
gene id: 643561:ACAV_RS18595
uniprot id: F0Q0X7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

643561:ACAV RS18935
gene id: 643561:ACAV_RS18935
uniprot id: F0Q1S0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19695
gene id: 643561:ACAV_RS19695
uniprot id: F0Q3F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

643561:ACAV RS16850
gene id: 643561:ACAV_RS16850
uniprot id: F0QAR5
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

643561:ACAV RS20005
gene id: 643561:ACAV_RS20005
uniprot id: F0Q493
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

643561:ACAV RS20240
gene id: 643561:ACAV_RS20240
uniprot id: F0Q514
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

643561:ACAV RS20140
gene id: 643561:ACAV_RS20140
uniprot id: F0Q4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane

643561:ACAV RS21650
gene id: 643561:ACAV_RS21650
uniprot id: F0Q7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS19710
gene id: 643561:ACAV_RS19710
uniprot id: F0Q3G2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

643561:ACAV RS20185
gene id: 643561:ACAV_RS20185
uniprot id: F0Q4C9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS20545
gene id: 643561:ACAV_RS20545
uniprot id: F0Q576
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS16975
gene id: 643561:ACAV_RS16975
uniprot id: F0QAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

643561:ACAV RS11015
gene id: 643561:ACAV_RS11015
uniprot id: F0QBH8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS09780
gene id: 643561:ACAV_RS09780
uniprot id: F0Q8W0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

643561:ACAV RS04065
gene id: 643561:ACAV_RS04065
uniprot id: F0Q8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

643561:ACAV RS01535
gene id: 643561:ACAV_RS01535
uniprot id: F0Q3J8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

643561:ACAV RS06090
gene id: 643561:ACAV_RS06090
uniprot id: F0Q0E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

643561:ACAV RS09720
gene id: 643561:ACAV_RS09720
uniprot id: F0Q8U8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS09155
gene id: 643561:ACAV_RS09155
uniprot id: F0Q789
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS06265
gene id: 643561:ACAV_RS06265
uniprot id: F0Q0H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643561:ACAV RS00775
gene id: 643561:ACAV_RS00775
uniprot id: F0Q1V4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

643561:ACAV RS13095
gene id: 643561:ACAV_RS13095
uniprot id: F0Q2B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

643561:ACAV RS15960
gene id: 643561:ACAV_RS15960
uniprot id: F0Q8C5
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS13740
gene id: 643561:ACAV_RS13740
uniprot id: F0Q397
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

643561:ACAV RS00480
gene id: 643561:ACAV_RS00480
uniprot id: F0Q118
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS02430
gene id: 643561:ACAV_RS02430
uniprot id: F0Q5C4
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

643561:ACAV RS06525
gene id: 643561:ACAV_RS06525
uniprot id: F0Q1A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

643561:ACAV RS10840
gene id: 643561:ACAV_RS10840
uniprot id: F0QBE1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

643561:ACAV RS09180
gene id: 643561:ACAV_RS09180
uniprot id: F0Q794
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

643561:ACAV RS09255
gene id: 643561:ACAV_RS09255
uniprot id: F0Q7B0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

643561:ACAV RS00535
gene id: 643561:ACAV_RS00535
uniprot id: F0Q129
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS11430
gene id: 643561:ACAV_RS11430
uniprot id: F0QCD3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

643561:ACAV RS15370
gene id: 643561:ACAV_RS15370
uniprot id: F0Q7C9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS11275
gene id: 643561:ACAV_RS11275
uniprot id: F0QCA4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS09535
gene id: 643561:ACAV_RS09535
uniprot id: F0Q844
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS02120
gene id: 643561:ACAV_RS02120
uniprot id: F0Q4I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

643561:ACAV RS10445
gene id: 643561:ACAV_RS10445
uniprot id: F0QAI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

643561:ACAV RS19940
gene id: 643561:ACAV_RS19940
uniprot id: F0Q480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

643561:ACAV RS09905
gene id: 643561:ACAV_RS09905
uniprot id: F0Q8Y4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

643561:ACAV RS18590
gene id: 643561:ACAV_RS18590
uniprot id: F0Q0X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS12745
gene id: 643561:ACAV_RS12745
uniprot id: F0Q1G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

643561:ACAV RS04160
gene id: 643561:ACAV_RS04160
uniprot id: F0Q9H0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

643561:ACAV RS14585
gene id: 643561:ACAV_RS14585
uniprot id: F0Q509
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

643561:ACAV RS22110
gene id: 643561:ACAV_RS22110
uniprot id: F0Q4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

643561:ACAV RS05665
gene id: 643561:ACAV_RS05665
uniprot id: F0QCT8
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

643561:ACAV RS21020
gene id: 643561:ACAV_RS21020
uniprot id: F0Q6R8
names: Similarity
messages: Belongs to the leucine-binding protein family.

643561:ACAV RS17780
gene id: 643561:ACAV_RS17780
uniprot id: F0QCK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS01815
gene id: 643561:ACAV_RS01815
uniprot id: F0Q3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS15150
gene id: 643561:ACAV_RS15150
uniprot id: F0Q6L2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

643561:ACAV RS03710
gene id: 643561:ACAV_RS03710
uniprot id: F0Q801
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS01155
gene id: 643561:ACAV_RS01155
uniprot id: F0Q2Q3
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS05060
gene id: 643561:ACAV_RS05060
uniprot id: F0QB95
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS06750
gene id: 643561:ACAV_RS06750
uniprot id: F0Q228
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

643561:ACAV RS05860
gene id: 643561:ACAV_RS05860
uniprot id: F0QCX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

643561:ACAV RS17890
gene id: 643561:ACAV_RS17890
uniprot id: F0QCM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

643561:ACAV RS06460
gene id: 643561:ACAV_RS06460
uniprot id: F0Q193
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

643561:ACAV RS22705
gene id: 643561:ACAV_RS22705
uniprot id: F0QA83
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS10725
gene id: 643561:ACAV_RS10725
uniprot id: F0QAP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

643561:ACAV RS07580
gene id: 643561:ACAV_RS07580
uniprot id: F0Q3T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS01160
gene id: 643561:ACAV_RS01160
uniprot id: F0Q2Q4
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS21365
gene id: 643561:ACAV_RS21365
uniprot id: F0Q7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

643561:ACAV RS05840
gene id: 643561:ACAV_RS05840
uniprot id: F0QCX4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

643561:ACAV RS15060
gene id: 643561:ACAV_RS15060
uniprot id: F0Q6J4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS16315
gene id: 643561:ACAV_RS16315
uniprot id: F0Q963
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

643561:ACAV RS09430
gene id: 643561:ACAV_RS09430
uniprot id: F0Q822
names: Similarity
messages: Belongs to the VgrG protein family.

643561:ACAV RS19775
gene id: 643561:ACAV_RS19775
uniprot id: F0Q3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS12790
gene id: 643561:ACAV_RS12790
uniprot id: F0Q1H2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

643561:ACAV RS21350
gene id: 643561:ACAV_RS21350
uniprot id: F0Q7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

643561:ACAV RS09245
gene id: 643561:ACAV_RS09245
uniprot id: F0Q7A7
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

643561:ACAV RS23185
gene id: 643561:ACAV_RS23185
uniprot id: F0QBT3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

643561:ACAV RS00895
gene id: 643561:ACAV_RS00895
uniprot id: F0Q1X9
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

643561:ACAV RS08515
gene id: 643561:ACAV_RS08515
uniprot id: F0Q5L4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS10330
gene id: 643561:ACAV_RS10330
uniprot id: F0Q9T8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS22740
gene id: 643561:ACAV_RS22740
uniprot id: F0QA90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

643561:ACAV RS22285
gene id: 643561:ACAV_RS22285
uniprot id: F0Q9C0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

643561:ACAV RS11870
gene id: 643561:ACAV_RS11870
uniprot id: F0QD67
names: Similarity
messages: Belongs to the VgrG protein family.

643561:ACAV RS21435
gene id: 643561:ACAV_RS21435
uniprot id: F0Q7M2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

643561:ACAV RS21300
gene id: 643561:ACAV_RS21300
uniprot id: F0Q6W9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

643561:ACAV RS11210
gene id: 643561:ACAV_RS11210
uniprot id: F0QC91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

643561:ACAV RS01615
gene id: 643561:ACAV_RS01615
uniprot id: F0Q3L4
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS17900
gene id: 643561:ACAV_RS17900
uniprot id: F0QCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

643561:ACAV RS17410
gene id: 643561:ACAV_RS17410
uniprot id: F0QBQ7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

643561:ACAV RS16455
gene id: 643561:ACAV_RS16455
uniprot id: F0Q9W1
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

643561:ACAV RS14905
gene id: 643561:ACAV_RS14905
uniprot id: F0Q5U9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS06045
gene id: 643561:ACAV_RS06045
uniprot id: F0Q0D4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS12840
gene id: 643561:ACAV_RS12840
uniprot id: F0Q1I2
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS01885
gene id: 643561:ACAV_RS01885
uniprot id: F0Q4E1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19290
gene id: 643561:ACAV_RS19290
uniprot id: F0Q2L4
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

643561:ACAV RS16180
gene id: 643561:ACAV_RS16180
uniprot id: F0Q936
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643561:ACAV RS17430
gene id: 643561:ACAV_RS17430
uniprot id: F0QBR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS02150
gene id: 643561:ACAV_RS02150
uniprot id: F0Q4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

643561:ACAV RS07740
gene id: 643561:ACAV_RS07740
uniprot id: F0Q3W4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS23180
gene id: 643561:ACAV_RS23180
uniprot id: F0QB53
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS09205
gene id: 643561:ACAV_RS09205
uniprot id: F0Q799
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS22335
gene id: 643561:ACAV_RS22335
uniprot id: F0Q9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

643561:ACAV RS09335
gene id: 643561:ACAV_RS09335
uniprot id: F0Q7C6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS19970
gene id: 643561:ACAV_RS19970
uniprot id: F0Q486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Membrane

643561:ACAV RS07890
gene id: 643561:ACAV_RS07890
uniprot id: F0Q4L8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS16285
gene id: 643561:ACAV_RS16285
uniprot id: F0Q957
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS12885
gene id: 643561:ACAV_RS12885
uniprot id: F0Q1J1
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

643561:ACAV RS15265
gene id: 643561:ACAV_RS15265
uniprot id: F0Q6N5
names: Similarity
messages: Belongs to the UxaA family.

643561:ACAV RS22675
gene id: 643561:ACAV_RS22675
uniprot id: F0QA77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS03690
gene id: 643561:ACAV_RS03690
uniprot id: F0Q7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

643561:ACAV RS19205
gene id: 643561:ACAV_RS19205
uniprot id: F0Q2J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

643561:ACAV RS15935
gene id: 643561:ACAV_RS15935
uniprot id: F0Q8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

643561:ACAV RS22355
gene id: 643561:ACAV_RS22355
uniprot id: F0Q9D4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

643561:ACAV RS20090
gene id: 643561:ACAV_RS20090
uniprot id: F0Q4B0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

643561:ACAV RS01945
gene id: 643561:ACAV_RS01945
uniprot id: F0Q4F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

643561:ACAV RS10930
gene id: 643561:ACAV_RS10930
uniprot id: F0QBG1
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

643561:ACAV RS06975
gene id: 643561:ACAV_RS06975
uniprot id: F0Q275
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

643561:ACAV RS23900
gene id: 643561:ACAV_RS23900
uniprot id: F0QBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

643561:ACAV RS12325
gene id: 643561:ACAV_RS12325
uniprot id: F0Q0K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS07245
gene id: 643561:ACAV_RS07245
uniprot id: F0Q2Z5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

643561:ACAV RS09550
gene id: 643561:ACAV_RS09550
uniprot id: F0Q847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

643561:ACAV RS10795
gene id: 643561:ACAV_RS10795
uniprot id: F0QAQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

643561:ACAV RS11835
gene id: 643561:ACAV_RS11835
uniprot id: F0QD60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS16890
gene id: 643561:ACAV_RS16890
uniprot id: F0QAS3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

643561:ACAV RS09750
gene id: 643561:ACAV_RS09750
uniprot id: F0Q8V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS03080
gene id: 643561:ACAV_RS03080
uniprot id: F0Q6Z7
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS13340
gene id: 643561:ACAV_RS13340
uniprot id: F0Q2F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

643561:ACAV RS12135
gene id: 643561:ACAV_RS12135
uniprot id: F0QDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS12940
gene id: 643561:ACAV_RS12940
uniprot id: F0Q1K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS20890
gene id: 643561:ACAV_RS20890
uniprot id: F0Q618
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS18730
gene id: 643561:ACAV_RS18730
uniprot id: F0Q1M9
names: Similarity
messages: Belongs to the peptidase M16 family.

643561:ACAV RS11280
gene id: 643561:ACAV_RS11280
uniprot id: F0QCA5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS09185
gene id: 643561:ACAV_RS09185
uniprot id: F0Q795
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

643561:ACAV RS07780
gene id: 643561:ACAV_RS07780
uniprot id: F0Q3X2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

643561:ACAV RS00170
gene id: 643561:ACAV_RS00170
uniprot id: F0Q077
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

643561:ACAV RS06695
gene id: 643561:ACAV_RS06695
uniprot id: F0Q1E1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS03275
gene id: 643561:ACAV_RS03275
uniprot id: F0Q737
names: Similarity
messages: Belongs to the IlvD/Edd family.

643561:ACAV RS01570
gene id: 643561:ACAV_RS01570
uniprot id: F0Q3K5
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS03695
gene id: 643561:ACAV_RS03695
uniprot id: F0Q7Z7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

643561:ACAV RS18820
gene id: 643561:ACAV_RS18820
uniprot id: F0Q1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS06005
gene id: 643561:ACAV_RS06005
uniprot id: F0Q0C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

643561:ACAV RS22425
gene id: 643561:ACAV_RS22425
uniprot id: F0Q9E8
names: Similarity
messages: Belongs to the PspA/IM30 family.

643561:ACAV RS09950
gene id: 643561:ACAV_RS09950
uniprot id: F0Q8Z3
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

643561:ACAV RS17605
gene id: 643561:ACAV_RS17605
uniprot id: F0QCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS14625
gene id: 643561:ACAV_RS14625
uniprot id: F0Q5P1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS03550
gene id: 643561:ACAV_RS03550
uniprot id: F0Q7W8
names: Similarity
messages: Belongs to the GST superfamily.

643561:ACAV RS21190
gene id: 643561:ACAV_RS21190
uniprot id: F0Q6U7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

643561:ACAV RS06105
gene id: 643561:ACAV_RS06105
uniprot id: F0Q0E6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

643561:ACAV RS05585
gene id: 643561:ACAV_RS05585
uniprot id: F0QC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS23755
gene id: 643561:ACAV_RS23755
uniprot id: F0QCS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

643561:ACAV RS06300
gene id: 643561:ACAV_RS06300
uniprot id: F0Q0I4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

643561:ACAV RS23165
gene id: 643561:ACAV_RS23165
uniprot id: F0QB50
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

643561:ACAV RS22250
gene id: 643561:ACAV_RS22250
uniprot id: F0Q9B3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS19100
gene id: 643561:ACAV_RS19100
uniprot id: F0Q2H8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS15675
gene id: 643561:ACAV_RS15675
uniprot id: F0Q7J2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

643561:ACAV RS10265
gene id: 643561:ACAV_RS10265
uniprot id: F0Q9S5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS09170
gene id: 643561:ACAV_RS09170
uniprot id: F0Q792
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

643561:ACAV RS13135
gene id: 643561:ACAV_RS13135
uniprot id: F0Q2B8
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

643561:ACAV RS25195
gene id: 643561:ACAV_RS25195
uniprot id: F0QCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

643561:ACAV RS00805
gene id: 643561:ACAV_RS00805
uniprot id: F0Q1W0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS00020
gene id: 643561:ACAV_RS00020
uniprot id: F0Q048
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

643561:ACAV RS07180
gene id: 643561:ACAV_RS07180
uniprot id: F0Q2Y7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

643561:ACAV RS07175
gene id: 643561:ACAV_RS07175
uniprot id: F0Q2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

643561:ACAV RS17445
gene id: 643561:ACAV_RS17445
uniprot id: F0QBR4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

643561:ACAV RS20155
gene id: 643561:ACAV_RS20155
uniprot id: F0Q4C3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

643561:ACAV RS10125
gene id: 643561:ACAV_RS10125
uniprot id: F0Q9P6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

643561:ACAV RS17715
gene id: 643561:ACAV_RS17715
uniprot id: F0QCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS09695
gene id: 643561:ACAV_RS09695
uniprot id: F0Q876
names: Similarity
messages: Belongs to the oxoprolinase family.

643561:ACAV RS13620
gene id: 643561:ACAV_RS13620
uniprot id: F0Q375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS17930
gene id: 643561:ACAV_RS17930
uniprot id: F0QDF7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS20895
gene id: 643561:ACAV_RS20895
uniprot id: F0Q619
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS10355
gene id: 643561:ACAV_RS10355
uniprot id: F0Q9U3
names: Similarity
messages: Belongs to the leucine-binding protein family.

643561:ACAV RS02755
gene id: 643561:ACAV_RS02755
uniprot id: F0Q662
names: Similarity
messages: Belongs to the Dps family.

643561:ACAV RS03980
gene id: 643561:ACAV_RS03980
uniprot id: F0Q8S2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS05870
gene id: 643561:ACAV_RS05870
uniprot id: F0QCY0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

643561:ACAV RS16240
gene id: 643561:ACAV_RS16240
uniprot id: F0Q948
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

643561:ACAV RS18385
gene id: 643561:ACAV_RS18385
uniprot id: F0Q0T6
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS02760
gene id: 643561:ACAV_RS02760
uniprot id: F0Q663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

643561:ACAV RS00060
gene id: 643561:ACAV_RS00060
uniprot id: F0Q055
names: Similarity
messages: Belongs to the HsdR family.

643561:ACAV RS18660
gene id: 643561:ACAV_RS18660
uniprot id: F0Q0Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

643561:ACAV RS13660
gene id: 643561:ACAV_RS13660
uniprot id: F0Q383
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

643561:ACAV RS23670
gene id: 643561:ACAV_RS23670
uniprot id: F0QCQ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643561:ACAV RS13560
gene id: 643561:ACAV_RS13560
uniprot id: F0Q363
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

643561:ACAV RS06490
gene id: 643561:ACAV_RS06490
uniprot id: F0Q199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

643561:ACAV RS20945
gene id: 643561:ACAV_RS20945
uniprot id: F0Q629
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19365
gene id: 643561:ACAV_RS19365
uniprot id: F0Q2M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS10405
gene id: 643561:ACAV_RS10405
uniprot id: F0Q9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

643561:ACAV RS07210
gene id: 643561:ACAV_RS07210
uniprot id: F0Q2Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

643561:ACAV RS06335
gene id: 643561:ACAV_RS06335
uniprot id: F0Q0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

643561:ACAV RS19830
gene id: 643561:ACAV_RS19830
uniprot id: F0Q3I6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS11920
gene id: 643561:ACAV_RS11920
uniprot id: F0QD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

643561:ACAV RS02100
gene id: 643561:ACAV_RS02100
uniprot id: F0Q4I5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

643561:ACAV RS18800
gene id: 643561:ACAV_RS18800
uniprot id: F0Q1P3
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS12435
gene id: 643561:ACAV_RS12435
uniprot id: F0Q0M4
names: Subcellular Location Annotation
messages: Periplasm

643561:ACAV RS20590
gene id: 643561:ACAV_RS20590
uniprot id: F0Q585
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

643561:ACAV RS01870
gene id: 643561:ACAV_RS01870
uniprot id: F0Q4D8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643561:ACAV RS00230
gene id: 643561:ACAV_RS00230
uniprot id: F0Q088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643561:ACAV RS14480
gene id: 643561:ACAV_RS14480
uniprot id: F0Q4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

643561:ACAV RS15315
gene id: 643561:ACAV_RS15315
uniprot id: F0Q6P5
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

643561:ACAV RS07975
gene id: 643561:ACAV_RS07975
uniprot id: F0Q4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

643561:ACAV RS02340
gene id: 643561:ACAV_RS02340
uniprot id: F0Q5A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

643561:ACAV RS13500
gene id: 643561:ACAV_RS13500
uniprot id: F0Q351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

643561:ACAV RS19920
gene id: 643561:ACAV_RS19920
uniprot id: F0Q476
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS00640
gene id: 643561:ACAV_RS00640
uniprot id: F0Q153
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

643561:ACAV RS12315
gene id: 643561:ACAV_RS12315
uniprot id: F0Q0K1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

643561:ACAV RS00125
gene id: 643561:ACAV_RS00125
uniprot id: F0Q068
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

643561:ACAV RS15250
gene id: 643561:ACAV_RS15250
uniprot id: F0Q6N2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS21265
gene id: 643561:ACAV_RS21265
uniprot id: F0Q6W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

643561:ACAV RS16490
gene id: 643561:ACAV_RS16490
uniprot id: F0Q9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS22965
gene id: 643561:ACAV_RS22965
uniprot id: F0QB09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

643561:ACAV RS02525
gene id: 643561:ACAV_RS02525
uniprot id: F0Q5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS14910
gene id: 643561:ACAV_RS14910
uniprot id: F0Q5V0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS18765
gene id: 643561:ACAV_RS18765
uniprot id: F0Q1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS01745
gene id: 643561:ACAV_RS01745
uniprot id: F0Q3P0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643561:ACAV RS15610
gene id: 643561:ACAV_RS15610
uniprot id: F0Q7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

643561:ACAV RS18450
gene id: 643561:ACAV_RS18450
uniprot id: F0Q0U9
names: Similarity
messages: Belongs to the VgrG protein family.

643561:ACAV RS13250
gene id: 643561:ACAV_RS13250
uniprot id: F0Q2E1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS03620
gene id: 643561:ACAV_RS03620
uniprot id: F0Q7Y2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

643561:ACAV RS14355
gene id: 643561:ACAV_RS14355
uniprot id: F0Q4W3
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

643561:ACAV RS02690
gene id: 643561:ACAV_RS02690
uniprot id: F0Q648
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS01845
gene id: 643561:ACAV_RS01845
uniprot id: F0Q3R2
names: Similarity
messages: Belongs to the hemerythrin family.

643561:ACAV RS00455
gene id: 643561:ACAV_RS00455
uniprot id: F0Q113
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

643561:ACAV RS23560
gene id: 643561:ACAV_RS23560
uniprot id: F0QCN7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

643561:ACAV RS14490
gene id: 643561:ACAV_RS14490
uniprot id: F0Q4Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

643561:ACAV RS09500
gene id: 643561:ACAV_RS09500
uniprot id: F0Q837
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS01530
gene id: 643561:ACAV_RS01530
uniprot id: F0Q3J7
names: Similarity
messages: Belongs to the GST superfamily.

643561:ACAV RS06595
gene id: 643561:ACAV_RS06595
uniprot id: F0Q1C0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

643561:ACAV RS20855
gene id: 643561:ACAV_RS20855
uniprot id: F0Q611
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

643561:ACAV RS20595
gene id: 643561:ACAV_RS20595
uniprot id: F0Q5W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

643561:ACAV RS02695
gene id: 643561:ACAV_RS02695
uniprot id: F0Q650
names: Similarity
messages: Belongs to the TrpC family.

643561:ACAV RS05005
gene id: 643561:ACAV_RS05005
uniprot id: F0QB84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

643561:ACAV RS08635
gene id: 643561:ACAV_RS08635
uniprot id: F0Q6B2
names: Subcellular Location Annotation
messages: Periplasm

643561:ACAV RS17095
gene id: 643561:ACAV_RS17095
uniprot id: F0QAW7
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

643561:ACAV RS15930
gene id: 643561:ACAV_RS15930
uniprot id: F0Q8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS06720
gene id: 643561:ACAV_RS06720
uniprot id: F0Q1E6
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

643561:ACAV RS14615
gene id: 643561:ACAV_RS14615
uniprot id: F0Q5N9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

643561:ACAV RS01670
gene id: 643561:ACAV_RS01670
uniprot id: F0Q3M5
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS00745
gene id: 643561:ACAV_RS00745
uniprot id: F0Q174
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

643561:ACAV RS00115
gene id: 643561:ACAV_RS00115
uniprot id: F0Q066
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

643561:ACAV RS02850
gene id: 643561:ACAV_RS02850
uniprot id: F0Q681
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

643561:ACAV RS16875
gene id: 643561:ACAV_RS16875
uniprot id: F0QAS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

643561:ACAV RS23485
gene id: 643561:ACAV_RS23485
uniprot id: F0QBZ5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS19005
gene id: 643561:ACAV_RS19005
uniprot id: F0Q1T4
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

643561:ACAV RS19485
gene id: 643561:ACAV_RS19485
uniprot id: F0Q3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS21370
gene id: 643561:ACAV_RS21370
uniprot id: F0Q7K9
names: Similarity
messages: Belongs to the type III secretion exporter family.

643561:ACAV RS20835
gene id: 643561:ACAV_RS20835
uniprot id: F0Q607
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS22840
gene id: 643561:ACAV_RS22840
uniprot id: F0QAY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

643561:ACAV RS18505
gene id: 643561:ACAV_RS18505
uniprot id: F0Q0V9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

643561:ACAV RS21275
gene id: 643561:ACAV_RS21275
uniprot id: F0Q6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS12820
gene id: 643561:ACAV_RS12820
uniprot id: F0Q1H8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

643561:ACAV RS20110
gene id: 643561:ACAV_RS20110
uniprot id: F0Q4B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS07545
gene id: 643561:ACAV_RS07545
uniprot id: F0Q3S3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

643561:ACAV RS16440
gene id: 643561:ACAV_RS16440
uniprot id: F0Q988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS10340
gene id: 643561:ACAV_RS10340
uniprot id: F0Q9U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

643561:ACAV RS11525
gene id: 643561:ACAV_RS11525
uniprot id: F0QCF2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

643561:ACAV RS02510
gene id: 643561:ACAV_RS02510
uniprot id: F0Q5E0
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

643561:ACAV RS06225
gene id: 643561:ACAV_RS06225
uniprot id: F0Q0H0
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS00900
gene id: 643561:ACAV_RS00900
uniprot id: F0Q1Y0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS07715
gene id: 643561:ACAV_RS07715
uniprot id: F0Q3V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

643561:ACAV RS23700
gene id: 643561:ACAV_RS23700
uniprot id: F0QCR5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

643561:ACAV RS08735
gene id: 643561:ACAV_RS08735
uniprot id: F0Q6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

643561:ACAV RS22955
gene id: 643561:ACAV_RS22955
uniprot id: F0QB07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

643561:ACAV RS11385
gene id: 643561:ACAV_RS11385
uniprot id: F0QCC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS22290
gene id: 643561:ACAV_RS22290
uniprot id: F0Q9C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

643561:ACAV RS13100
gene id: 643561:ACAV_RS13100
uniprot id: F0Q2B1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS18270
gene id: 643561:ACAV_RS18270
uniprot id: F0QDM2
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS06275
gene id: 643561:ACAV_RS06275
uniprot id: F0Q0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS13790
gene id: 643561:ACAV_RS13790
uniprot id: F0Q3A6
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

643561:ACAV RS01355
gene id: 643561:ACAV_RS01355
uniprot id: F0Q2U2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

643561:ACAV RS20665
gene id: 643561:ACAV_RS20665
uniprot id: F0Q5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS00650
gene id: 643561:ACAV_RS00650
uniprot id: F0Q155
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS12800
gene id: 643561:ACAV_RS12800
uniprot id: F0Q1H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

643561:ACAV RS05940
gene id: 643561:ACAV_RS05940
uniprot id: F0QCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

643561:ACAV RS08570
gene id: 643561:ACAV_RS08570
uniprot id: F0Q5M4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

643561:ACAV RS16225
gene id: 643561:ACAV_RS16225
uniprot id: F0Q945
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

643561:ACAV RS06020
gene id: 643561:ACAV_RS06020
uniprot id: F0Q0C8
names: Similarity
messages: Belongs to the TrpF family.

643561:ACAV RS18115
gene id: 643561:ACAV_RS18115
uniprot id: F0QDJ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS14060
gene id: 643561:ACAV_RS14060
uniprot id: F0Q434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS15805
gene id: 643561:ACAV_RS15805
uniprot id: F0Q894
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

643561:ACAV RS03365
gene id: 643561:ACAV_RS03365
uniprot id: F0Q7T2
names: Similarity
messages: Belongs to the CFA/CMAS family.

643561:ACAV RS18400
gene id: 643561:ACAV_RS18400
uniprot id: F0Q0T9
names: Similarity
messages: Belongs to the UPF0758 family.

643561:ACAV RS20480
gene id: 643561:ACAV_RS20480
uniprot id: F0Q563
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS04130
gene id: 643561:ACAV_RS04130
uniprot id: F0Q9G3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS07300
gene id: 643561:ACAV_RS07300
uniprot id: F0Q306
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

643561:ACAV RS12890
gene id: 643561:ACAV_RS12890
uniprot id: F0Q1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS05635
gene id: 643561:ACAV_RS05635
uniprot id: F0QCT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

643561:ACAV RS15645
gene id: 643561:ACAV_RS15645
uniprot id: F0Q7I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

643561:ACAV RS05360
gene id: 643561:ACAV_RS05360
uniprot id: F0QC33
names: Similarity
messages: Belongs to the asparagine synthetase family.

643561:ACAV RS11230
gene id: 643561:ACAV_RS11230
uniprot id: F0QC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643561:ACAV RS17800
gene id: 643561:ACAV_RS17800
uniprot id: F0QCL0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

643561:ACAV RS15115
gene id: 643561:ACAV_RS15115
uniprot id: F0Q6K5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

643561:ACAV RS09855
gene id: 643561:ACAV_RS09855
uniprot id: F0Q8X4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

643561:ACAV RS16550
gene id: 643561:ACAV_RS16550
uniprot id: F0Q9Y0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

643561:ACAV RS07145
gene id: 643561:ACAV_RS07145
uniprot id: F0Q2Y0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

643561:ACAV RS23520
gene id: 643561:ACAV_RS23520
uniprot id: F0QC02
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS20320
gene id: 643561:ACAV_RS20320
uniprot id: F0Q531
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS14655
gene id: 643561:ACAV_RS14655
uniprot id: F0Q5P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS14295
gene id: 643561:ACAV_RS14295
uniprot id: F0Q4V1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS07035
gene id: 643561:ACAV_RS07035
uniprot id: F0Q288
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

643561:ACAV RS09845
gene id: 643561:ACAV_RS09845
uniprot id: F0Q8X2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

643561:ACAV RS03755
gene id: 643561:ACAV_RS03755
uniprot id: F0Q8M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

643561:ACAV RS23140
gene id: 643561:ACAV_RS23140
uniprot id: F0QB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS04110
gene id: 643561:ACAV_RS04110
uniprot id: F0Q9F9
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

643561:ACAV RS18645
gene id: 643561:ACAV_RS18645
uniprot id: F0Q0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

643561:ACAV RS11170
gene id: 643561:ACAV_RS11170
uniprot id: F0QC83
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

643561:ACAV RS20195
gene id: 643561:ACAV_RS20195
uniprot id: F0Q4D1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

643561:ACAV RS11545
gene id: 643561:ACAV_RS11545
uniprot id: F0QCF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

643561:ACAV RS04020
gene id: 643561:ACAV_RS04020
uniprot id: F0Q8T0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS10980
gene id: 643561:ACAV_RS10980
uniprot id: F0QBH1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS18770
gene id: 643561:ACAV_RS18770
uniprot id: F0Q1N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

643561:ACAV RS22415
gene id: 643561:ACAV_RS22415
uniprot id: F0Q9E6
names: Similarity
messages: Belongs to the peptidase M24B family.

643561:ACAV RS23350
gene id: 643561:ACAV_RS23350
uniprot id: F0QBW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS02015
gene id: 643561:ACAV_RS02015
uniprot id: F0Q4G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

643561:ACAV RS21140
gene id: 643561:ACAV_RS21140
uniprot id: F0Q6U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

643561:ACAV RS11580
gene id: 643561:ACAV_RS11580
uniprot id: F0QD10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

643561:ACAV RS05790
gene id: 643561:ACAV_RS05790
uniprot id: F0QCW4
names: Similarity
messages: Belongs to the UPF0246 family.

643561:ACAV RS00630
gene id: 643561:ACAV_RS00630
uniprot id: F0Q151
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

643561:ACAV RS14745
gene id: 643561:ACAV_RS14745
uniprot id: F0Q5R5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

643561:ACAV RS13310
gene id: 643561:ACAV_RS13310
uniprot id: F0Q2E8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS12955
gene id: 643561:ACAV_RS12955
uniprot id: F0Q1K5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS04705
gene id: 643561:ACAV_RS04705
uniprot id: F0QAF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

643561:ACAV RS19415
gene id: 643561:ACAV_RS19415
uniprot id: F0Q2N8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

643561:ACAV RS16860
gene id: 643561:ACAV_RS16860
uniprot id: F0QAR7
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19020
gene id: 643561:ACAV_RS19020
uniprot id: F0Q1T7
names: Similarity
messages: Belongs to the YciI family.

643561:ACAV RS07065
gene id: 643561:ACAV_RS07065
uniprot id: F0Q294
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

643561:ACAV RS00700
gene id: 643561:ACAV_RS00700
uniprot id: F0Q165
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS13700
gene id: 643561:ACAV_RS13700
uniprot id: F0Q391
names: Similarity
messages: Belongs to the histone deacetylase family.

643561:ACAV RS03990
gene id: 643561:ACAV_RS03990
uniprot id: F0Q8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

643561:ACAV RS00955
gene id: 643561:ACAV_RS00955
uniprot id: F0Q1Z1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

643561:ACAV RS05660
gene id: 643561:ACAV_RS05660
uniprot id: F0QCT7
names: Similarity
messages: Belongs to the DEAD box helicase family.

643561:ACAV RS14445
gene id: 643561:ACAV_RS14445
uniprot id: F0Q4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

643561:ACAV RS15995
gene id: 643561:ACAV_RS15995
uniprot id: F0Q8D2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

643561:ACAV RS19980
gene id: 643561:ACAV_RS19980
uniprot id: F0Q488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS05850
gene id: 643561:ACAV_RS05850
uniprot id: F0QCX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

643561:ACAV RS07685
gene id: 643561:ACAV_RS07685
uniprot id: F0Q3V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

643561:ACAV RS05780
gene id: 643561:ACAV_RS05780
uniprot id: F0QCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS20885
gene id: 643561:ACAV_RS20885
uniprot id: F0Q617
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS15190
gene id: 643561:ACAV_RS15190
uniprot id: F0Q6M0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

643561:ACAV RS01280
gene id: 643561:ACAV_RS01280
uniprot id: F0Q2S7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

643561:ACAV RS09865
gene id: 643561:ACAV_RS09865
uniprot id: F0Q8X6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

643561:ACAV RS20910
gene id: 643561:ACAV_RS20910
uniprot id: F0Q622
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS16350
gene id: 643561:ACAV_RS16350
uniprot id: F0Q970
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS09200
gene id: 643561:ACAV_RS09200
uniprot id: F0Q798
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

643561:ACAV RS04265
gene id: 643561:ACAV_RS04265
uniprot id: F0Q9J1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

643561:ACAV RS16410
gene id: 643561:ACAV_RS16410
uniprot id: F0Q982
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

643561:ACAV RS12500
gene id: 643561:ACAV_RS12500
uniprot id: F0Q0N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

643561:ACAV RS09505
gene id: 643561:ACAV_RS09505
uniprot id: F0Q838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS16855
gene id: 643561:ACAV_RS16855
uniprot id: F0QAR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

643561:ACAV RS02805
gene id: 643561:ACAV_RS02805
uniprot id: F0Q672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS23875
gene id: 643561:ACAV_RS23875
uniprot id: F0Q527
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS00730
gene id: 643561:ACAV_RS00730
uniprot id: F0Q171
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

643561:ACAV RS20615
gene id: 643561:ACAV_RS20615
uniprot id: F0Q5W5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

643561:ACAV RS06565
gene id: 643561:ACAV_RS06565
uniprot id: F0Q1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

643561:ACAV RS06325
gene id: 643561:ACAV_RS06325
uniprot id: F0Q0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS01455
gene id: 643561:ACAV_RS01455
uniprot id: F0Q2W5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

643561:ACAV RS13730
gene id: 643561:ACAV_RS13730
uniprot id: F0Q395
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

643561:ACAV RS11770
gene id: 643561:ACAV_RS11770
uniprot id: F0QD47
names: Cofactor
messages: Can also use Mn(2+) ion.

643561:ACAV RS23320
gene id: 643561:ACAV_RS23320
uniprot id: F0QBW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS12730
gene id: 643561:ACAV_RS12730
uniprot id: F0Q1G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

643561:ACAV RS05605
gene id: 643561:ACAV_RS05605
uniprot id: F0QC82
names: Similarity
messages: Belongs to the glycosyl hydrolase 100 family.

643561:ACAV RS22325
gene id: 643561:ACAV_RS22325
uniprot id: F0Q9C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS18530
gene id: 643561:ACAV_RS18530
uniprot id: F0Q0W4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS11435
gene id: 643561:ACAV_RS11435
uniprot id: F0QCD4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

643561:ACAV RS12085
gene id: 643561:ACAV_RS12085
uniprot id: F0QDB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

643561:ACAV RS08855
gene id: 643561:ACAV_RS08855
uniprot id: F0Q6F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

643561:ACAV RS01095
gene id: 643561:ACAV_RS01095
uniprot id: F0Q219
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

643561:ACAV RS05470
gene id: 643561:ACAV_RS05470
uniprot id: F0QC55
names: Similarity
messages: Belongs to the RutC family.

643561:ACAV RS14540
gene id: 643561:ACAV_RS14540
uniprot id: F0Q500
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

643561:ACAV RS17850
gene id: 643561:ACAV_RS17850
uniprot id: F0QCL9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

643561:ACAV RS21415
gene id: 643561:ACAV_RS21415
uniprot id: F0Q7L8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

643561:ACAV RS17950
gene id: 643561:ACAV_RS17950
uniprot id: F0QDG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS08285
gene id: 643561:ACAV_RS08285
uniprot id: F0Q5H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS07115
gene id: 643561:ACAV_RS07115
uniprot id: F0Q2X4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

643561:ACAV RS01635
gene id: 643561:ACAV_RS01635
uniprot id: F0Q3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

643561:ACAV RS15620
gene id: 643561:ACAV_RS15620
uniprot id: F0Q7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS14220
gene id: 643561:ACAV_RS14220
uniprot id: F0Q4T8
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS13165
gene id: 643561:ACAV_RS13165
uniprot id: F0Q2C4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

643561:ACAV RS08245
gene id: 643561:ACAV_RS08245
uniprot id: F0Q5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

643561:ACAV RS16515
gene id: 643561:ACAV_RS16515
uniprot id: F0Q9X3
names: Similarity
messages: Belongs to the acetyltransferase YopJ family.

643561:ACAV RS06640
gene id: 643561:ACAV_RS06640
uniprot id: F0Q1D0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS03675
gene id: 643561:ACAV_RS03675
uniprot id: F0Q7Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

643561:ACAV RS15640
gene id: 643561:ACAV_RS15640
uniprot id: F0Q7I5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

643561:ACAV RS12425
gene id: 643561:ACAV_RS12425
uniprot id: F0Q0M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

643561:ACAV RS00860
gene id: 643561:ACAV_RS00860
uniprot id: F0Q1X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).
messages: TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates.

643561:ACAV RS07670
gene id: 643561:ACAV_RS07670
uniprot id: F0Q3V0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS08415
gene id: 643561:ACAV_RS08415
uniprot id: F0Q5J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS03595
gene id: 643561:ACAV_RS03595
uniprot id: F0Q7X7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

643561:ACAV RS10590
gene id: 643561:ACAV_RS10590
uniprot id: F0QAL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS14755
gene id: 643561:ACAV_RS14755
uniprot id: F0Q5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

643561:ACAV RS01770
gene id: 643561:ACAV_RS01770
uniprot id: F0Q3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS15530
gene id: 643561:ACAV_RS15530
uniprot id: F0Q7G2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

643561:ACAV RS03820
gene id: 643561:ACAV_RS03820
uniprot id: F0Q8P0
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

643561:ACAV RS06340
gene id: 643561:ACAV_RS06340
uniprot id: F0Q0J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS13000
gene id: 643561:ACAV_RS13000
uniprot id: F0Q1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

643561:ACAV RS08235
gene id: 643561:ACAV_RS08235
uniprot id: F0Q4T4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

643561:ACAV RS06160
gene id: 643561:ACAV_RS06160
uniprot id: F0Q0F7
names: Similarity
messages: Belongs to the MoaD family.

643561:ACAV RS02835
gene id: 643561:ACAV_RS02835
uniprot id: F0Q678
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

643561:ACAV RS18190
gene id: 643561:ACAV_RS18190
uniprot id: F0QDK8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

643561:ACAV RS16585
gene id: 643561:ACAV_RS16585
uniprot id: F0Q9Y7
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS06645
gene id: 643561:ACAV_RS06645
uniprot id: F0Q1D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

643561:ACAV RS06205
gene id: 643561:ACAV_RS06205
uniprot id: F0Q0G6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS23570
gene id: 643561:ACAV_RS23570
uniprot id: F0QCP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

643561:ACAV RS16810
gene id: 643561:ACAV_RS16810
uniprot id: F0QAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS20145
gene id: 643561:ACAV_RS20145
uniprot id: F0Q4C1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

643561:ACAV RS02010
gene id: 643561:ACAV_RS02010
uniprot id: F0Q4G6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

643561:ACAV RS05750
gene id: 643561:ACAV_RS05750
uniprot id: F0QCV6
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

643561:ACAV RS10870
gene id: 643561:ACAV_RS10870
uniprot id: F0QBE9
names: Similarity
messages: Belongs to the peptidase S66 family.

643561:ACAV RS08725
gene id: 643561:ACAV_RS08725
uniprot id: F0Q6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

643561:ACAV RS01040
gene id: 643561:ACAV_RS01040
uniprot id: F0Q208
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

643561:ACAV RS06420
gene id: 643561:ACAV_RS06420
uniprot id: F0Q185
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

643561:ACAV RS06120
gene id: 643561:ACAV_RS06120
uniprot id: F0Q0E9
names: Similarity
messages: Belongs to the PhoH family.

643561:ACAV RS11215
gene id: 643561:ACAV_RS11215
uniprot id: F0QC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

643561:ACAV RS11195
gene id: 643561:ACAV_RS11195
uniprot id: F0QC88
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-70 and Arg-73) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

643561:ACAV RS07640
gene id: 643561:ACAV_RS07640
uniprot id: F0Q3U4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS10450
gene id: 643561:ACAV_RS10450
uniprot id: F0QAI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

643561:ACAV RS19915
gene id: 643561:ACAV_RS19915
uniprot id: F0Q475
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643561:ACAV RS00570
gene id: 643561:ACAV_RS00570
uniprot id: F0Q136
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS10635
gene id: 643561:ACAV_RS10635
uniprot id: F0QAM4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS21310
gene id: 643561:ACAV_RS21310
uniprot id: F0Q6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

643561:ACAV RS19200
gene id: 643561:ACAV_RS19200
uniprot id: F0Q2J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

643561:ACAV RS23330
gene id: 643561:ACAV_RS23330
uniprot id: F0QBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

643561:ACAV RS13925
gene id: 643561:ACAV_RS13925
uniprot id: F0Q407
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS16500
gene id: 643561:ACAV_RS16500
uniprot id: F0Q9X0
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

643561:ACAV RS04985
gene id: 643561:ACAV_RS04985
uniprot id: F0QB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

643561:ACAV RS00875
gene id: 643561:ACAV_RS00875
uniprot id: F0Q1X5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS11785
gene id: 643561:ACAV_RS11785
uniprot id: F0QD50
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

643561:ACAV RS15680
gene id: 643561:ACAV_RS15680
uniprot id: F0Q7J3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

643561:ACAV RS08510
gene id: 643561:ACAV_RS08510
uniprot id: F0Q5L3
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS16165
gene id: 643561:ACAV_RS16165
uniprot id: F0Q933
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

643561:ACAV RS01500
gene id: 643561:ACAV_RS01500
uniprot id: F0Q3J1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

643561:ACAV RS06070
gene id: 643561:ACAV_RS06070
uniprot id: F0Q0D9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

643561:ACAV RS07495
gene id: 643561:ACAV_RS07495
uniprot id: F0Q3R5
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

643561:ACAV RS15925
gene id: 643561:ACAV_RS15925
uniprot id: F0Q8B8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS08560
gene id: 643561:ACAV_RS08560
uniprot id: F0Q5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

643561:ACAV RS13820
gene id: 643561:ACAV_RS13820
uniprot id: F0Q3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS21570
gene id: 643561:ACAV_RS21570
uniprot id: F0Q7P8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

643561:ACAV RS12310
gene id: 643561:ACAV_RS12310
uniprot id: F0QDF6
names: Similarity
messages: Belongs to the peptidase S33 family.

643561:ACAV RS04975
gene id: 643561:ACAV_RS04975
uniprot id: F0QB78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

643561:ACAV RS04360
gene id: 643561:ACAV_RS04360
uniprot id: F0Q9L0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS19040
gene id: 643561:ACAV_RS19040
uniprot id: F0Q1U1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

643561:ACAV RS18240
gene id: 643561:ACAV_RS18240
uniprot id: F0QDL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS15155
gene id: 643561:ACAV_RS15155
uniprot id: F0Q6L3
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS03640
gene id: 643561:ACAV_RS03640
uniprot id: F0Q7Y6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS04250
gene id: 643561:ACAV_RS04250
uniprot id: F0Q9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS06580
gene id: 643561:ACAV_RS06580
uniprot id: F0Q1B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

643561:ACAV RS02845
gene id: 643561:ACAV_RS02845
uniprot id: F0Q680
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

643561:ACAV RS02575
gene id: 643561:ACAV_RS02575
uniprot id: F0Q5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

643561:ACAV RS04455
gene id: 643561:ACAV_RS04455
uniprot id: F0Q9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

643561:ACAV RS22745
gene id: 643561:ACAV_RS22745
uniprot id: F0QA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS19210
gene id: 643561:ACAV_RS19210
uniprot id: F0Q2J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

643561:ACAV RS06845
gene id: 643561:ACAV_RS06845
uniprot id: F0Q248
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS10900
gene id: 643561:ACAV_RS10900
uniprot id: F0QBF5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS11115
gene id: 643561:ACAV_RS11115
uniprot id: F0QBJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

643561:ACAV RS21625
gene id: 643561:ACAV_RS21625
uniprot id: F0Q7R0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS02320
gene id: 643561:ACAV_RS02320
uniprot id: F0Q5A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

643561:ACAV RS08365
gene id: 643561:ACAV_RS08365
uniprot id: F0Q5I6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

643561:ACAV RS23580
gene id: 643561:ACAV_RS23580
uniprot id: F0QCP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

643561:ACAV RS13715
gene id: 643561:ACAV_RS13715
uniprot id: F0Q392
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

643561:ACAV RS15550
gene id: 643561:ACAV_RS15550
uniprot id: F0Q7G6
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

643561:ACAV RS03400
gene id: 643561:ACAV_RS03400
uniprot id: F0Q7T9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS17295
gene id: 643561:ACAV_RS17295
uniprot id: F0QBN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

643561:ACAV RS20850
gene id: 643561:ACAV_RS20850
uniprot id: F0Q610
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

643561:ACAV RS07135
gene id: 643561:ACAV_RS07135
uniprot id: F0Q2X8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

643561:ACAV RS04220
gene id: 643561:ACAV_RS04220
uniprot id: F0Q9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS00310
gene id: 643561:ACAV_RS00310
uniprot id: F0Q0A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

643561:ACAV RS12185
gene id: 643561:ACAV_RS12185
uniprot id: F0QDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS16460
gene id: 643561:ACAV_RS16460
uniprot id: F0Q9W2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

643561:ACAV RS19525
gene id: 643561:ACAV_RS19525
uniprot id: F0Q3C5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS17465
gene id: 643561:ACAV_RS17465
uniprot id: F0QBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

643561:ACAV RS02125
gene id: 643561:ACAV_RS02125
uniprot id: F0Q4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

643561:ACAV RS01710
gene id: 643561:ACAV_RS01710
uniprot id: F0Q3N3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

643561:ACAV RS05935
gene id: 643561:ACAV_RS05935
uniprot id: F0QCZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

643561:ACAV RS11575
gene id: 643561:ACAV_RS11575
uniprot id: F0QD09
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

643561:ACAV RS00435
gene id: 643561:ACAV_RS00435
uniprot id: F0Q109
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

643561:ACAV RS02900
gene id: 643561:ACAV_RS02900
uniprot id: F0Q692
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

643561:ACAV RS04650
gene id: 643561:ACAV_RS04650
uniprot id: F0QAE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

643561:ACAV RS01750
gene id: 643561:ACAV_RS01750
uniprot id: F0Q3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS22030
gene id: 643561:ACAV_RS22030
uniprot id: F0Q8L0
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS20475
gene id: 643561:ACAV_RS20475
uniprot id: F0Q562
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

643561:ACAV RS00185
gene id: 643561:ACAV_RS00185
uniprot id: F0Q080
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

643561:ACAV RS04790
gene id: 643561:ACAV_RS04790
uniprot id: F0QAH0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

643561:ACAV RS02700
gene id: 643561:ACAV_RS02700
uniprot id: F0Q651
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

643561:ACAV RS13105
gene id: 643561:ACAV_RS13105
uniprot id: F0Q2B2
names: Similarity
messages: Belongs to the asparaginase 1 family.

643561:ACAV RS07110
gene id: 643561:ACAV_RS07110
uniprot id: F0Q2X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

643561:ACAV RS14750
gene id: 643561:ACAV_RS14750
uniprot id: F0Q5R6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

643561:ACAV RS05435
gene id: 643561:ACAV_RS05435
uniprot id: F0QC48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

643561:ACAV RS23740
gene id: 643561:ACAV_RS23740
uniprot id: F0QCS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

643561:ACAV RS11800
gene id: 643561:ACAV_RS11800
uniprot id: F0QD53
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643561:ACAV RS04845
gene id: 643561:ACAV_RS04845
uniprot id: F0QAI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS05695
gene id: 643561:ACAV_RS05695
uniprot id: F0QCU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

643561:ACAV RS12200
gene id: 643561:ACAV_RS12200
uniprot id: F0QDD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

643561:ACAV RS10135
gene id: 643561:ACAV_RS10135
uniprot id: F0Q9P8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

643561:ACAV RS06320
gene id: 643561:ACAV_RS06320
uniprot id: F0Q0I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS19235
gene id: 643561:ACAV_RS19235
uniprot id: F0Q2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

643561:ACAV RS10715
gene id: 643561:ACAV_RS10715
uniprot id: F0QAP0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS23030
gene id: 643561:ACAV_RS23030
uniprot id: F0QB24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS06000
gene id: 643561:ACAV_RS06000
uniprot id: F0Q0C4
names: Similarity
messages: Belongs to the YggT family.

643561:ACAV RS08790
gene id: 643561:ACAV_RS08790
uniprot id: F0Q6E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS12770
gene id: 643561:ACAV_RS12770
uniprot id: F0Q1G8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

643561:ACAV RS22475
gene id: 643561:ACAV_RS22475
uniprot id: F0QA35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS19790
gene id: 643561:ACAV_RS19790
uniprot id: F0Q3H8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS20535
gene id: 643561:ACAV_RS20535
uniprot id: F0Q574
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

643561:ACAV RS23445
gene id: 643561:ACAV_RS23445
uniprot id: F0QBY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

643561:ACAV RS23990
gene id: 643561:ACAV_RS23990
uniprot id: F0Q9G5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

643561:ACAV RS00180
gene id: 643561:ACAV_RS00180
uniprot id: F0Q079
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

643561:ACAV RS03575
gene id: 643561:ACAV_RS03575
uniprot id: F0Q7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

643561:ACAV RS02915
gene id: 643561:ACAV_RS02915
uniprot id: F0Q694
names: Similarity
messages: Belongs to the heat shock protein 70 family.

643561:ACAV RS13760
gene id: 643561:ACAV_RS13760
uniprot id: F0Q3A1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

643561:ACAV RS12565
gene id: 643561:ACAV_RS12565
uniprot id: F0Q0Q0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

643561:ACAV RS22230
gene id: 643561:ACAV_RS22230
uniprot id: F0Q9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

643561:ACAV RS19665
gene id: 643561:ACAV_RS19665
uniprot id: F0Q3F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

643561:ACAV RS13915
gene id: 643561:ACAV_RS13915
uniprot id: F0Q405
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

643561:ACAV RS14440
gene id: 643561:ACAV_RS14440
uniprot id: F0Q4Y0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

643561:ACAV RS20450
gene id: 643561:ACAV_RS20450
uniprot id: F0Q557
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

643561:ACAV RS17855
gene id: 643561:ACAV_RS17855
uniprot id: F0QCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

643561:ACAV RS14030
gene id: 643561:ACAV_RS14030
uniprot id: F0Q428
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

643561:ACAV RS09970
gene id: 643561:ACAV_RS09970
uniprot id: F0Q8Z7
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

643561:ACAV RS20075
gene id: 643561:ACAV_RS20075
uniprot id: F0Q4A7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

643561:ACAV RS04980
gene id: 643561:ACAV_RS04980
uniprot id: F0QB79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS03775
gene id: 643561:ACAV_RS03775
uniprot id: F0Q8N1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS02275
gene id: 643561:ACAV_RS02275
uniprot id: F0Q593
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

643561:ACAV RS02235
gene id: 643561:ACAV_RS02235
uniprot id: F0Q4L2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS12130
gene id: 643561:ACAV_RS12130
uniprot id: F0QDB9
names: Similarity
messages: Belongs to the peptidase S41A family.

643561:ACAV RS05865
gene id: 643561:ACAV_RS05865
uniprot id: F0QCX9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

643561:ACAV RS17915
gene id: 643561:ACAV_RS17915
uniprot id: F0QCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

643561:ACAV RS18575
gene id: 643561:ACAV_RS18575
uniprot id: F0Q0X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS15755
gene id: 643561:ACAV_RS15755
uniprot id: F0Q884
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS11740
gene id: 643561:ACAV_RS11740
uniprot id: F0QD41
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

643561:ACAV RS02000
gene id: 643561:ACAV_RS02000
uniprot id: F0Q4G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

643561:ACAV RS08095
gene id: 643561:ACAV_RS08095
uniprot id: F0Q4Q6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS04490
gene id: 643561:ACAV_RS04490
uniprot id: F0QAB0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

643561:ACAV RS18885
gene id: 643561:ACAV_RS18885
uniprot id: F0Q1R0
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

643561:ACAV RS14265
gene id: 643561:ACAV_RS14265
uniprot id: F0Q4U6
names: Similarity
messages: Belongs to the TPP enzyme family.

643561:ACAV RS18535
gene id: 643561:ACAV_RS18535
uniprot id: F0Q0W5
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell inner membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

643561:ACAV RS15025
gene id: 643561:ACAV_RS15025
uniprot id: F0Q6I7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS16230
gene id: 643561:ACAV_RS16230
uniprot id: F0Q946
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

643561:ACAV RS02115
gene id: 643561:ACAV_RS02115
uniprot id: F0Q4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

643561:ACAV RS07010
gene id: 643561:ACAV_RS07010
uniprot id: F0Q282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS05900
gene id: 643561:ACAV_RS05900
uniprot id: F0QCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

643561:ACAV RS15030
gene id: 643561:ACAV_RS15030
uniprot id: F0Q6I8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS17895
gene id: 643561:ACAV_RS17895
uniprot id: F0QCM7
names: Cofactor
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

643561:ACAV RS16485
gene id: 643561:ACAV_RS16485
uniprot id: F0Q9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

643561:ACAV RS14955
gene id: 643561:ACAV_RS14955
uniprot id: F0Q5V8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

643561:ACAV RS11635
gene id: 643561:ACAV_RS11635
uniprot id: F0QD20
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS03155
gene id: 643561:ACAV_RS03155
uniprot id: F0Q712
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS13110
gene id: 643561:ACAV_RS13110
uniprot id: F0Q2B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

643561:ACAV RS12025
gene id: 643561:ACAV_RS12025
uniprot id: F0QD98
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

643561:ACAV RS18490
gene id: 643561:ACAV_RS18490
uniprot id: F0Q0V6
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS21470
gene id: 643561:ACAV_RS21470
uniprot id: F0Q7M9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS06655
gene id: 643561:ACAV_RS06655
uniprot id: F0Q1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

643561:ACAV RS04565
gene id: 643561:ACAV_RS04565
uniprot id: F0QAC5
names: Function
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

643561:ACAV RS12430
gene id: 643561:ACAV_RS12430
uniprot id: F0Q0M3
names: Subcellular Location Annotation
messages: Periplasm

643561:ACAV RS12825
gene id: 643561:ACAV_RS12825
uniprot id: F0Q1H9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS00765
gene id: 643561:ACAV_RS00765
uniprot id: F0Q1V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

643561:ACAV RS21235
gene id: 643561:ACAV_RS21235
uniprot id: F0Q6V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Role in flagellar biosynthesis.

643561:ACAV RS13510
gene id: 643561:ACAV_RS13510
uniprot id: F0Q353
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

643561:ACAV RS06930
gene id: 643561:ACAV_RS06930
uniprot id: F0Q266
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

643561:ACAV RS09645
gene id: 643561:ACAV_RS09645
uniprot id: F0Q866
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

643561:ACAV RS11310
gene id: 643561:ACAV_RS11310
uniprot id: F0QCB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS10690
gene id: 643561:ACAV_RS10690
uniprot id: F0QAN5
names: Similarity
messages: Belongs to the LOG family.

643561:ACAV RS11220
gene id: 643561:ACAV_RS11220
uniprot id: F0QC93
names: Similarity
messages: Belongs to the peptidase M24B family.

643561:ACAV RS11360
gene id: 643561:ACAV_RS11360
uniprot id: F0QCC1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

643561:ACAV RS07005
gene id: 643561:ACAV_RS07005
uniprot id: F0Q281
names: Similarity
messages: Belongs to the DapA family.

643561:ACAV RS08915
gene id: 643561:ACAV_RS08915
uniprot id: F0Q6G7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS23335
gene id: 643561:ACAV_RS23335
uniprot id: F0QBW3
names: Subcellular Location Annotation
messages: Secreted

643561:ACAV RS01720
gene id: 643561:ACAV_RS01720
uniprot id: F0Q3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

643561:ACAV RS22215
gene id: 643561:ACAV_RS22215
uniprot id: F0Q9A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

643561:ACAV RS06415
gene id: 643561:ACAV_RS06415
uniprot id: F0Q184
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS01975
gene id: 643561:ACAV_RS01975
uniprot id: F0Q4F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

643561:ACAV RS05745
gene id: 643561:ACAV_RS05745
uniprot id: F0QCV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

643561:ACAV RS15260
gene id: 643561:ACAV_RS15260
uniprot id: F0Q6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS01780
gene id: 643561:ACAV_RS01780
uniprot id: F0Q3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS14575
gene id: 643561:ACAV_RS14575
uniprot id: F0Q507
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

643561:ACAV RS02140
gene id: 643561:ACAV_RS02140
uniprot id: F0Q4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

643561:ACAV RS17230
gene id: 643561:ACAV_RS17230
uniprot id: F0QBM3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

643561:ACAV RS05775
gene id: 643561:ACAV_RS05775
uniprot id: F0QCW1
names: Similarity
messages: Belongs to the UPF0162 family.

643561:ACAV RS20220
gene id: 643561:ACAV_RS20220
uniprot id: F0Q510
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

643561:ACAV RS14205
gene id: 643561:ACAV_RS14205
uniprot id: F0Q4T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS02545
gene id: 643561:ACAV_RS02545
uniprot id: F0Q5E8
names: Similarity
messages: Belongs to the polysaccharide lyase 3 family.

643561:ACAV RS13070
gene id: 643561:ACAV_RS13070
uniprot id: F0Q2A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

643561:ACAV RS13195
gene id: 643561:ACAV_RS13195
uniprot id: F0Q2D0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

643561:ACAV RS16535
gene id: 643561:ACAV_RS16535
uniprot id: F0Q9X7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

643561:ACAV RS16755
gene id: 643561:ACAV_RS16755
uniprot id: F0QA23
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS20495
gene id: 643561:ACAV_RS20495
uniprot id: F0Q566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS10780
gene id: 643561:ACAV_RS10780
uniprot id: F0QAQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

643561:ACAV RS22240
gene id: 643561:ACAV_RS22240
uniprot id: F0Q9B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

643561:ACAV RS02890
gene id: 643561:ACAV_RS02890
uniprot id: F0Q690
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

643561:ACAV RS07810
gene id: 643561:ACAV_RS07810
uniprot id: F0Q3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

643561:ACAV RS13975
gene id: 643561:ACAV_RS13975
uniprot id: F0Q417
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

643561:ACAV RS18275
gene id: 643561:ACAV_RS18275
uniprot id: F0QDM3
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS09060
gene id: 643561:ACAV_RS09060
uniprot id: F0Q768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

643561:ACAV RS20365
gene id: 643561:ACAV_RS20365
uniprot id: F0Q540
names: Subcellular Location Annotation
messages: Mitochondrion

643561:ACAV RS13935
gene id: 643561:ACAV_RS13935
uniprot id: F0Q409
names: Similarity
messages: Belongs to the YkuD family.

643561:ACAV RS19885
gene id: 643561:ACAV_RS19885
uniprot id: F0Q469
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

643561:ACAV RS17455
gene id: 643561:ACAV_RS17455
uniprot id: F0QBR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

643561:ACAV RS17310
gene id: 643561:ACAV_RS17310
uniprot id: F0QBN9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

643561:ACAV RS13830
gene id: 643561:ACAV_RS13830
uniprot id: F0Q3B4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS09705
gene id: 643561:ACAV_RS09705
uniprot id: F0Q878
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS14270
gene id: 643561:ACAV_RS14270
uniprot id: F0Q4U7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

643561:ACAV RS06295
gene id: 643561:ACAV_RS06295
uniprot id: F0Q0I3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

643561:ACAV RS03225
gene id: 643561:ACAV_RS03225
uniprot id: F0Q726
names: Similarity
messages: Belongs to the VgrG protein family.

643561:ACAV RS21325
gene id: 643561:ACAV_RS21325
uniprot id: F0Q6X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

643561:ACAV RS05400
gene id: 643561:ACAV_RS05400
uniprot id: F0QC41
names: Similarity
messages: Belongs to the peptidase M20A family.

643561:ACAV RS02420
gene id: 643561:ACAV_RS02420
uniprot id: F0Q5C2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

643561:ACAV RS21410
gene id: 643561:ACAV_RS21410
uniprot id: F0Q7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

643561:ACAV RS01545
gene id: 643561:ACAV_RS01545
uniprot id: F0Q3K0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

643561:ACAV RS10335
gene id: 643561:ACAV_RS10335
uniprot id: F0Q9T9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS18370
gene id: 643561:ACAV_RS18370
uniprot id: F0Q0T3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS04685
gene id: 643561:ACAV_RS04685
uniprot id: F0QAE9
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS01835
gene id: 643561:ACAV_RS01835
uniprot id: F0Q3R0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

643561:ACAV RS02775
gene id: 643561:ACAV_RS02775
uniprot id: F0Q666
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS08885
gene id: 643561:ACAV_RS08885
uniprot id: F0Q6G1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

643561:ACAV RS06775
gene id: 643561:ACAV_RS06775
uniprot id: F0Q233
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS06630
gene id: 643561:ACAV_RS06630
uniprot id: F0Q1C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

643561:ACAV RS02225
gene id: 643561:ACAV_RS02225
uniprot id: F0Q4L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

643561:ACAV RS22735
gene id: 643561:ACAV_RS22735
uniprot id: F0QA89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

643561:ACAV RS11380
gene id: 643561:ACAV_RS11380
uniprot id: F0QCC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

643561:ACAV RS15070
gene id: 643561:ACAV_RS15070
uniprot id: F0Q6J6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

643561:ACAV RS17590
gene id: 643561:ACAV_RS17590
uniprot id: F0QCG8
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

643561:ACAV RS17620
gene id: 643561:ACAV_RS17620
uniprot id: F0QCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

643561:ACAV RS13985
gene id: 643561:ACAV_RS13985
uniprot id: F0Q419
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS11985
gene id: 643561:ACAV_RS11985
uniprot id: F0QD90
names: Similarity
messages: Belongs to the phosphohexose mutase family.

643561:ACAV RS07185
gene id: 643561:ACAV_RS07185
uniprot id: F0Q2Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

643561:ACAV RS19660
gene id: 643561:ACAV_RS19660
uniprot id: F0Q3F2
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS22025
gene id: 643561:ACAV_RS22025
uniprot id: F0Q8K9
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

643561:ACAV RS03685
gene id: 643561:ACAV_RS03685
uniprot id: F0Q7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

643561:ACAV RS15920
gene id: 643561:ACAV_RS15920
uniprot id: F0Q8B7
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS12795
gene id: 643561:ACAV_RS12795
uniprot id: F0Q1H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

643561:ACAV RS07635
gene id: 643561:ACAV_RS07635
uniprot id: F0Q3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS02060
gene id: 643561:ACAV_RS02060
uniprot id: F0Q4H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

643561:ACAV RS09065
gene id: 643561:ACAV_RS09065
uniprot id: F0Q769
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

643561:ACAV RS10505
gene id: 643561:ACAV_RS10505
uniprot id: F0QAJ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

643561:ACAV RS05110
gene id: 643561:ACAV_RS05110
uniprot id: F0QBA5
names: Similarity
messages: Belongs to the GSP E family.

643561:ACAV RS12225
gene id: 643561:ACAV_RS12225
uniprot id: F0QDD9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

643561:ACAV RS01115
gene id: 643561:ACAV_RS01115
uniprot id: F0Q223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS14590
gene id: 643561:ACAV_RS14590
uniprot id: F0Q5N4
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

643561:ACAV RS16395
gene id: 643561:ACAV_RS16395
uniprot id: F0Q979
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS05150
gene id: 643561:ACAV_RS05150
uniprot id: F0QBB5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS18540
gene id: 643561:ACAV_RS18540
uniprot id: F0Q0W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

643561:ACAV RS04595
gene id: 643561:ACAV_RS04595
uniprot id: F0QAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

643561:ACAV RS21690
gene id: 643561:ACAV_RS21690
uniprot id: F0Q7S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

643561:ACAV RS01950
gene id: 643561:ACAV_RS01950
uniprot id: F0Q4F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

643561:ACAV RS12705
gene id: 643561:ACAV_RS12705
uniprot id: F0Q1F5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

643561:ACAV RS19070
gene id: 643561:ACAV_RS19070
uniprot id: F0Q1U7
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS22720
gene id: 643561:ACAV_RS22720
uniprot id: F0QA86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

643561:ACAV RS08965
gene id: 643561:ACAV_RS08965
uniprot id: F0Q6H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS05655
gene id: 643561:ACAV_RS05655
uniprot id: F0QCT6
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS19140
gene id: 643561:ACAV_RS19140
uniprot id: F0Q2I5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

643561:ACAV RS04760
gene id: 643561:ACAV_RS04760
uniprot id: F0QAG4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

643561:ACAV RS19720
gene id: 643561:ACAV_RS19720
uniprot id: F0Q3G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

643561:ACAV RS03065
gene id: 643561:ACAV_RS03065
uniprot id: F0Q6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS16900
gene id: 643561:ACAV_RS16900
uniprot id: F0QAS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

643561:ACAV RS12105
gene id: 643561:ACAV_RS12105
uniprot id: F0QDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS09510
gene id: 643561:ACAV_RS09510
uniprot id: F0Q839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS07140
gene id: 643561:ACAV_RS07140
uniprot id: F0Q2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

643561:ACAV RS06935
gene id: 643561:ACAV_RS06935
uniprot id: F0Q267
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

643561:ACAV RS09995
gene id: 643561:ACAV_RS09995
uniprot id: F0Q902
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

643561:ACAV RS08910
gene id: 643561:ACAV_RS08910
uniprot id: F0Q6G6
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS20640
gene id: 643561:ACAV_RS20640
uniprot id: F0Q5X0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

643561:ACAV RS08840
gene id: 643561:ACAV_RS08840
uniprot id: F0Q6F2
names: Similarity
messages: Belongs to the FPG family.

643561:ACAV RS16105
gene id: 643561:ACAV_RS16105
uniprot id: F0Q922
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

643561:ACAV RS03795
gene id: 643561:ACAV_RS03795
uniprot id: F0Q8N5
names: Similarity
messages: Belongs to the peptidase U62 family.

643561:ACAV RS15340
gene id: 643561:ACAV_RS15340
uniprot id: F0Q6Q0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

643561:ACAV RS17785
gene id: 643561:ACAV_RS17785
uniprot id: F0QCK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

643561:ACAV RS02715
gene id: 643561:ACAV_RS02715
uniprot id: F0Q654
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

643561:ACAV RS09260
gene id: 643561:ACAV_RS09260
uniprot id: F0Q7B1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

643561:ACAV RS11420
gene id: 643561:ACAV_RS11420
uniprot id: F0QCD1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

643561:ACAV RS09135
gene id: 643561:ACAV_RS09135
uniprot id: F0Q785
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS23645
gene id: 643561:ACAV_RS23645
uniprot id: F0QCQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

643561:ACAV RS11045
gene id: 643561:ACAV_RS11045
uniprot id: F0QBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

643561:ACAV RS17035
gene id: 643561:ACAV_RS17035
uniprot id: F0QAV5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

643561:ACAV RS16290
gene id: 643561:ACAV_RS16290
uniprot id: F0Q958
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

643561:ACAV RS02390
gene id: 643561:ACAV_RS02390
uniprot id: F0Q5B6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

643561:ACAV RS06140
gene id: 643561:ACAV_RS06140
uniprot id: F0Q0F3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

643561:ACAV RS13065
gene id: 643561:ACAV_RS13065
uniprot id: F0Q2A4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

643561:ACAV RS11610
gene id: 643561:ACAV_RS11610
uniprot id: F0QD15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

643561:ACAV RS10740
gene id: 643561:ACAV_RS10740
uniprot id: F0QAP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

643561:ACAV RS23710
gene id: 643561:ACAV_RS23710
uniprot id: F0QCR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS08305
gene id: 643561:ACAV_RS08305
uniprot id: F0Q5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS11790
gene id: 643561:ACAV_RS11790
uniprot id: F0QD51
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

643561:ACAV RS19655
gene id: 643561:ACAV_RS19655
uniprot id: F0Q3F1
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

643561:ACAV RS08705
gene id: 643561:ACAV_RS08705
uniprot id: F0Q6C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

643561:ACAV RS17270
gene id: 643561:ACAV_RS17270
uniprot id: F0QBN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

643561:ACAV RS16035
gene id: 643561:ACAV_RS16035
uniprot id: F0Q8E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

643561:ACAV RS15400
gene id: 643561:ACAV_RS15400
uniprot id: F0Q7D5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

643561:ACAV RS04710
gene id: 643561:ACAV_RS04710
uniprot id: F0QAF4
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

643561:ACAV RS09655
gene id: 643561:ACAV_RS09655
uniprot id: F0Q868
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS22960
gene id: 643561:ACAV_RS22960
uniprot id: F0QB08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

643561:ACAV RS13840
gene id: 643561:ACAV_RS13840
uniprot id: F0Q3Z2
names: Similarity
messages: Belongs to the HSP15 family.

643561:ACAV RS08395
gene id: 643561:ACAV_RS08395
uniprot id: F0Q5J0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS22990
gene id: 643561:ACAV_RS22990
uniprot id: F0QB14
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

643561:ACAV RS06065
gene id: 643561:ACAV_RS06065
uniprot id: F0Q0D8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS06945
gene id: 643561:ACAV_RS06945
uniprot id: F0Q269
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

643561:ACAV RS23405
gene id: 643561:ACAV_RS23405
uniprot id: F0QBX8
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

643561:ACAV RS03985
gene id: 643561:ACAV_RS03985
uniprot id: F0Q8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

643561:ACAV RS20010
gene id: 643561:ACAV_RS20010
uniprot id: F0Q494
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

643561:ACAV RS18245
gene id: 643561:ACAV_RS18245
uniprot id: F0QDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

643561:ACAV RS06850
gene id: 643561:ACAV_RS06850
uniprot id: F0Q249
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

643561:ACAV RS07905
gene id: 643561:ACAV_RS07905
uniprot id: F0Q4M1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

643561:ACAV RS04225
gene id: 643561:ACAV_RS04225
uniprot id: F0Q9I3
names: Similarity
messages: Belongs to the ArsC family.

643561:ACAV RS12145
gene id: 643561:ACAV_RS12145
uniprot id: F0QDC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS04230
gene id: 643561:ACAV_RS04230
uniprot id: F0Q9I4
names: Similarity
messages: Belongs to the GSP E family.

643561:ACAV RS15970
gene id: 643561:ACAV_RS15970
uniprot id: F0Q8C7
names: Similarity
messages: Belongs to the GbsR family.

643561:ACAV RS04395
gene id: 643561:ACAV_RS04395
uniprot id: F0Q9L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

643561:ACAV RS04390
gene id: 643561:ACAV_RS04390
uniprot id: F0Q9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

643561:ACAV RS21710
gene id: 643561:ACAV_RS21710
uniprot id: F0Q7S7
names: Similarity
messages: Belongs to the GST superfamily.

643561:ACAV RS22865
gene id: 643561:ACAV_RS22865
uniprot id: F0QAY8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

643561:ACAV RS12700
gene id: 643561:ACAV_RS12700
uniprot id: F0Q1F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

643561:ACAV RS11320
gene id: 643561:ACAV_RS11320
uniprot id: F0QCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
messages: Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
messages: Secreted

643561:ACAV RS14555
gene id: 643561:ACAV_RS14555
uniprot id: F0Q503
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

643561:ACAV RS09270
gene id: 643561:ACAV_RS09270
uniprot id: F0Q7B3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

643561:ACAV RS18225
gene id: 643561:ACAV_RS18225
uniprot id: F0QDL3
names: Similarity
messages: Belongs to the VgrG protein family.

643561:ACAV RS01630
gene id: 643561:ACAV_RS01630
uniprot id: F0Q3L7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

643561:ACAV RS12650
gene id: 643561:ACAV_RS12650
uniprot id: F0Q0R8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

643561:ACAV RS09640
gene id: 643561:ACAV_RS09640
uniprot id: F0Q865
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

643561:ACAV RS17955
gene id: 643561:ACAV_RS17955
uniprot id: F0QDG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS09140
gene id: 643561:ACAV_RS09140
uniprot id: F0Q786
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS19355
gene id: 643561:ACAV_RS19355
uniprot id: F0Q2M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

643561:ACAV RS07000
gene id: 643561:ACAV_RS07000
uniprot id: F0Q280
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS13720
gene id: 643561:ACAV_RS13720
uniprot id: F0Q393
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

643561:ACAV RS15065
gene id: 643561:ACAV_RS15065
uniprot id: F0Q6J5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

643561:ACAV RS03810
gene id: 643561:ACAV_RS03810
uniprot id: F0Q8N8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

643561:ACAV RS03555
gene id: 643561:ACAV_RS03555
uniprot id: F0Q7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS00385
gene id: 643561:ACAV_RS00385
uniprot id: F0Q0C1
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS10730
gene id: 643561:ACAV_RS10730
uniprot id: F0QAP4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS04320
gene id: 643561:ACAV_RS04320
uniprot id: F0Q9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS15720
gene id: 643561:ACAV_RS15720
uniprot id: F0Q7K1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

643561:ACAV RS03700
gene id: 643561:ACAV_RS03700
uniprot id: F0Q7Z9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

643561:ACAV RS14340
gene id: 643561:ACAV_RS14340
uniprot id: F0Q4W0
names: Similarity
messages: Belongs to the IlvD/Edd family.

643561:ACAV RS04305
gene id: 643561:ACAV_RS04305
uniprot id: F0Q9J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

643561:ACAV RS23540
gene id: 643561:ACAV_RS23540
uniprot id: F0QC06
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

643561:ACAV RS09710
gene id: 643561:ACAV_RS09710
uniprot id: F0Q8U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS20880
gene id: 643561:ACAV_RS20880
uniprot id: F0Q616
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

643561:ACAV RS13085
gene id: 643561:ACAV_RS13085
uniprot id: F0Q2A8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

643561:ACAV RS12980
gene id: 643561:ACAV_RS12980
uniprot id: F0Q1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YfcJ family.
messages: Cell inner membrane
messages: Membrane

643561:ACAV RS23075
gene id: 643561:ACAV_RS23075
uniprot id: F0QB33
names: Similarity
messages: Belongs to the DapA family.

643561:ACAV RS18635
gene id: 643561:ACAV_RS18635
uniprot id: F0Q0Y5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

643561:ACAV RS17015
gene id: 643561:ACAV_RS17015
uniprot id: F0QAV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

643561:ACAV RS05265
gene id: 643561:ACAV_RS05265
uniprot id: F0QC13
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

643561:ACAV RS03005
gene id: 643561:ACAV_RS03005
uniprot id: F0Q6Y1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS04690
gene id: 643561:ACAV_RS04690
uniprot id: F0QAF0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

643561:ACAV RS19075
gene id: 643561:ACAV_RS19075
uniprot id: F0Q1U8
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

643561:ACAV RS16770
gene id: 643561:ACAV_RS16770
uniprot id: F0QA26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

643561:ACAV RS06785
gene id: 643561:ACAV_RS06785
uniprot id: F0Q235
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

643561:ACAV RS11825
gene id: 643561:ACAV_RS11825
uniprot id: F0QD58
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

643561:ACAV RS22770
gene id: 643561:ACAV_RS22770
uniprot id: F0QA96
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS02750
gene id: 643561:ACAV_RS02750
uniprot id: F0Q661
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS08340
gene id: 643561:ACAV_RS08340
uniprot id: F0Q5I1
names: Similarity
messages: Belongs to the peptidase S58 family.

643561:ACAV RS14420
gene id: 643561:ACAV_RS14420
uniprot id: F0Q4X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

643561:ACAV RS17585
gene id: 643561:ACAV_RS17585
uniprot id: F0QCG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

643561:ACAV RS17665
gene id: 643561:ACAV_RS17665
uniprot id: F0QCI3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

643561:ACAV RS01970
gene id: 643561:ACAV_RS01970
uniprot id: F0Q4F8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

643561:ACAV RS06520
gene id: 643561:ACAV_RS06520
uniprot id: F0Q1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS12600
gene id: 643561:ACAV_RS12600
uniprot id: F0Q0Q7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

643561:ACAV RS01995
gene id: 643561:ACAV_RS01995
uniprot id: F0Q4G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

643561:ACAV RS07070
gene id: 643561:ACAV_RS07070
uniprot id: F0Q295
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

643561:ACAV RS09895
gene id: 643561:ACAV_RS09895
uniprot id: F0Q8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

643561:ACAV RS19840
gene id: 643561:ACAV_RS19840
uniprot id: F0Q3I8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643561:ACAV RS12610
gene id: 643561:ACAV_RS12610
uniprot id: F0Q0Q9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

643561:ACAV RS22915
gene id: 643561:ACAV_RS22915
uniprot id: F0QAZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

643561:ACAV RS08020
gene id: 643561:ACAV_RS08020
uniprot id: F0Q4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

643561:ACAV RS02855
gene id: 643561:ACAV_RS02855
uniprot id: F0Q682
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

643561:ACAV RS01965
gene id: 643561:ACAV_RS01965
uniprot id: F0Q4F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

643561:ACAV RS10180
gene id: 643561:ACAV_RS10180
uniprot id: F0Q9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

643561:ACAV RS20150
gene id: 643561:ACAV_RS20150
uniprot id: F0Q4C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

643561:ACAV RS05465
gene id: 643561:ACAV_RS05465
uniprot id: F0QC54
names: Subcellular Location Annotation
messages: Membrane

643561:ACAV RS04960
gene id: 643561:ACAV_RS04960
uniprot id: F0QB75
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

643561:ACAV RS01725
gene id: 643561:ACAV_RS01725
uniprot id: F0Q3N6
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

643561:ACAV RS05960
gene id: 643561:ACAV_RS05960
uniprot id: F0QCZ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

643561:ACAV RS21665
gene id: 643561:ACAV_RS21665
uniprot id: F0Q7R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

643561:ACAV RS00095
gene id: 643561:ACAV_RS00095
uniprot id: F0Q062
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

643561:ACAV RS11690
gene id: 643561:ACAV_RS11690
uniprot id: F0QD31
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643561:ACAV RS07690
gene id: 643561:ACAV_RS07690
uniprot id: F0Q3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

643561:ACAV RS07305
gene id: 643561:ACAV_RS07305
uniprot id: F0Q307
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

643561:ACAV RS12215
gene id: 643561:ACAV_RS12215
uniprot id: F0QDD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

643561:ACAV RS03630
gene id: 643561:ACAV_RS03630
uniprot id: F0Q7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

643561:ACAV RS01260
gene id: 643561:ACAV_RS01260
uniprot id: F0Q2S3
names: Subunit
messages: Homodimer.

643561:ACAV RS04900
gene id: 643561:ACAV_RS04900
uniprot id: F0QB63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

643561:ACAV RS04295
gene id: 643561:ACAV_RS04295
uniprot id: F0Q9J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

643561:ACAV RS01225
gene id: 643561:ACAV_RS01225
uniprot id: F0Q2R6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS02680
gene id: 643561:ACAV_RS02680
uniprot id: F0Q646
names: Similarity
messages: Belongs to the DinB family.

643561:ACAV RS01915
gene id: 643561:ACAV_RS01915
uniprot id: F0Q4E7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

643561:ACAV RS04675
gene id: 643561:ACAV_RS04675
uniprot id: F0QAE7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

643561:ACAV RS02205
gene id: 643561:ACAV_RS02205
uniprot id: F0Q4K6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

643561:ACAV RS03535
gene id: 643561:ACAV_RS03535
uniprot id: F0Q7W5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

643561:ACAV RS22085
gene id: 643561:ACAV_RS22085
uniprot id: F0Q989
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

643561:ACAV RS02095
gene id: 643561:ACAV_RS02095
uniprot id: F0Q4I4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

643561:ACAV RS06285
gene id: 643561:ACAV_RS06285
uniprot id: F0Q0I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

643561:ACAV RS14570
gene id: 643561:ACAV_RS14570
uniprot id: F0Q506
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

643561:ACAV RS16430
gene id: 643561:ACAV_RS16430
uniprot id: F0Q986
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

643561:ACAV RS13910
gene id: 643561:ACAV_RS13910
uniprot id: F0Q404
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

643561:ACAV RS11200
gene id: 643561:ACAV_RS11200
uniprot id: F0QC89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

643561:ACAV RS17400
gene id: 643561:ACAV_RS17400
uniprot id: F0QBQ5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

643561:ACAV RS01895
gene id: 643561:ACAV_RS01895
uniprot id: F0Q4E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

643561:ACAV RS06830
gene id: 643561:ACAV_RS06830
uniprot id: F0Q245
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

643561:ACAV RS12635
gene id: 643561:ACAV_RS12635
uniprot id: F0Q0R4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

643561:ACAV RS15310
gene id: 643561:ACAV_RS15310
uniprot id: F0Q6P4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

643561:ACAV RS14810
gene id: 643561:ACAV_RS14810
uniprot id: F0Q5S9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

643561:ACAV RS22210
gene id: 643561:ACAV_RS22210
uniprot id: F0Q9A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

643561:ACAV RS19765
gene id: 643561:ACAV_RS19765
uniprot id: F0Q3H3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

643561:ACAV RS23235
gene id: 643561:ACAV_RS23235
uniprot id: F0QBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm