638303:THAL RS04100
gene id: 638303:THAL_RS04100
uniprot id: D3SL13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

638303:THAL RS07595
gene id: 638303:THAL_RS07595
uniprot id: D3SMZ3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

638303:THAL RS07945
gene id: 638303:THAL_RS07945
uniprot id: D3SN61
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

638303:THAL RS03835
gene id: 638303:THAL_RS03835
uniprot id: D3SQF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

638303:THAL RS06230
gene id: 638303:THAL_RS06230
uniprot id: D3SM75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

638303:THAL RS07700
gene id: 638303:THAL_RS07700
uniprot id: D3SN13
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

638303:THAL RS06690
gene id: 638303:THAL_RS06690
uniprot id: D3SMG6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

638303:THAL RS07250
gene id: 638303:THAL_RS07250
uniprot id: D3SMS5
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS04705
gene id: 638303:THAL_RS04705
uniprot id: D3SLC5
names: Similarity
messages: Belongs to the SCO1/2 family.

638303:THAL RS01830
gene id: 638303:THAL_RS01830
uniprot id: D3SPB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

638303:THAL RS00140
gene id: 638303:THAL_RS00140
uniprot id: D3SND0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

638303:THAL RS05705
gene id: 638303:THAL_RS05705
uniprot id: D3SLX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

638303:THAL RS04760
gene id: 638303:THAL_RS04760
uniprot id: D3SLD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

638303:THAL RS01835
gene id: 638303:THAL_RS01835
uniprot id: D3SPB7
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03785
gene id: 638303:THAL_RS03785
uniprot id: D3SQE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

638303:THAL RS05365
gene id: 638303:THAL_RS05365
uniprot id: D3SLQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

638303:THAL RS03505
gene id: 638303:THAL_RS03505
uniprot id: D3SQ92
names: Function
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

638303:THAL RS07190
gene id: 638303:THAL_RS07190
uniprot id: D3SMR3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

638303:THAL RS07020
gene id: 638303:THAL_RS07020
uniprot id: D3SMN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

638303:THAL RS06720
gene id: 638303:THAL_RS06720
uniprot id: D3SMH2
names: Similarity
messages: Belongs to the CmpA/NrtA family.

638303:THAL RS01265
gene id: 638303:THAL_RS01265
uniprot id: D3SP05
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS05630
gene id: 638303:THAL_RS05630
uniprot id: D3SLV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

638303:THAL RS06730
gene id: 638303:THAL_RS06730
uniprot id: D3SMH4
names: Similarity
messages: Belongs to the P(II) protein family.

638303:THAL RS07130
gene id: 638303:THAL_RS07130
uniprot id: D3SMQ1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

638303:THAL RS03120
gene id: 638303:THAL_RS03120
uniprot id: D3SQ21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cellular thylakoid membrane
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

638303:THAL RS02505
gene id: 638303:THAL_RS02505
uniprot id: D3SPQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

638303:THAL RS00790
gene id: 638303:THAL_RS00790
uniprot id: D3SNQ9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

638303:THAL RS06055
gene id: 638303:THAL_RS06055
uniprot id: D3SM39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

638303:THAL RS02295
gene id: 638303:THAL_RS02295
uniprot id: D3SPK8
names: Similarity
messages: Belongs to the peptidase S8 family.

638303:THAL RS07650
gene id: 638303:THAL_RS07650
uniprot id: D3SN04
names: Similarity
messages: Belongs to the SCO1/2 family.

638303:THAL RS06105
gene id: 638303:THAL_RS06105
uniprot id: D3SM49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

638303:THAL RS02170
gene id: 638303:THAL_RS02170
uniprot id: D3SPI4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

638303:THAL RS00760
gene id: 638303:THAL_RS00760
uniprot id: D3SNQ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

638303:THAL RS01955
gene id: 638303:THAL_RS01955
uniprot id: D3SPE1
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS07600
gene id: 638303:THAL_RS07600
uniprot id: D3SMZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS03800
gene id: 638303:THAL_RS03800
uniprot id: D3SQF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

638303:THAL RS06390
gene id: 638303:THAL_RS06390
uniprot id: D3SMA7
names: Similarity
messages: Belongs to the GSP E family.

638303:THAL RS04075
gene id: 638303:THAL_RS04075
uniprot id: D3SL08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

638303:THAL RS02430
gene id: 638303:THAL_RS02430
uniprot id: D3SPN5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

638303:THAL RS05050
gene id: 638303:THAL_RS05050
uniprot id: D3SLJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

638303:THAL RS05960
gene id: 638303:THAL_RS05960
uniprot id: D3SM21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

638303:THAL RS07115
gene id: 638303:THAL_RS07115
uniprot id: D3SMP8
names: Similarity
messages: Belongs to the universal stress protein A family.

638303:THAL RS00970
gene id: 638303:THAL_RS00970
uniprot id: D3SNU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

638303:THAL RS00545
gene id: 638303:THAL_RS00545
uniprot id: D3SNL1
names: Similarity
messages: Belongs to the GSP E family.

638303:THAL RS05140
gene id: 638303:THAL_RS05140
uniprot id: D3SLL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

638303:THAL RS06775
gene id: 638303:THAL_RS06775
uniprot id: D3SMI3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

638303:THAL RS02130
gene id: 638303:THAL_RS02130
uniprot id: D3SPH6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

638303:THAL RS01360
gene id: 638303:THAL_RS01360
uniprot id: D3SP23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

638303:THAL RS05300
gene id: 638303:THAL_RS05300
uniprot id: D3SLP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

638303:THAL RS05980
gene id: 638303:THAL_RS05980
uniprot id: D3SM25
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS07015
gene id: 638303:THAL_RS07015
uniprot id: D3SMN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

638303:THAL RS04650
gene id: 638303:THAL_RS04650
uniprot id: D3SLB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

638303:THAL RS06785
gene id: 638303:THAL_RS06785
uniprot id: D3SMI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

638303:THAL RS04755
gene id: 638303:THAL_RS04755
uniprot id: D3SLD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS06870
gene id: 638303:THAL_RS06870
uniprot id: D3SMK2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

638303:THAL RS06380
gene id: 638303:THAL_RS06380
uniprot id: D3SMA5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS05305
gene id: 638303:THAL_RS05305
uniprot id: D3SLP3
names: Similarity
messages: Belongs to the HypE family.

638303:THAL RS05130
gene id: 638303:THAL_RS05130
uniprot id: D3SLK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

638303:THAL RS03285
gene id: 638303:THAL_RS03285
uniprot id: D3SQ48
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

638303:THAL RS01795
gene id: 638303:THAL_RS01795
uniprot id: D3SPA9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

638303:THAL RS05780
gene id: 638303:THAL_RS05780
uniprot id: D3SLY8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

638303:THAL RS07755
gene id: 638303:THAL_RS07755
uniprot id: D3SN24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

638303:THAL RS01245
gene id: 638303:THAL_RS01245
uniprot id: D3SP01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

638303:THAL RS00520
gene id: 638303:THAL_RS00520
uniprot id: D3SNK6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

638303:THAL RS03730
gene id: 638303:THAL_RS03730
uniprot id: D3SQD6
names: Similarity
messages: Belongs to the YggT family.

638303:THAL RS08025
gene id: 638303:THAL_RS08025
uniprot id: D3SN78
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

638303:THAL RS03760
gene id: 638303:THAL_RS03760
uniprot id: D3SQE2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

638303:THAL RS07305
gene id: 638303:THAL_RS07305
uniprot id: D3SMT6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

638303:THAL RS02000
gene id: 638303:THAL_RS02000
uniprot id: D3SPF1
names: Similarity
messages: Belongs to the peptidase U62 family.

638303:THAL RS07870
gene id: 638303:THAL_RS07870
uniprot id: D3SN45
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

638303:THAL RS02945
gene id: 638303:THAL_RS02945
uniprot id: D3SPY6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

638303:THAL RS07415
gene id: 638303:THAL_RS07415
uniprot id: D3SMV9
names: Subcellular Location Annotation
messages: Cytoplasm

638303:THAL RS01940
gene id: 638303:THAL_RS01940
uniprot id: D3SPD8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS00830
gene id: 638303:THAL_RS00830
uniprot id: D3SNR7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS07655
gene id: 638303:THAL_RS07655
uniprot id: D3SN05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

638303:THAL RS01715
gene id: 638303:THAL_RS01715
uniprot id: D3SP93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

638303:THAL RS02035
gene id: 638303:THAL_RS02035
uniprot id: D3SPF8
names: Similarity
messages: Belongs to the P(II) protein family.

638303:THAL RS03960
gene id: 638303:THAL_RS03960
uniprot id: D3SQI0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

638303:THAL RS01615
gene id: 638303:THAL_RS01615
uniprot id: D3SP74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

638303:THAL RS05860
gene id: 638303:THAL_RS05860
uniprot id: D3SM02
names: Similarity
messages: Belongs to the UPF0751 family.

638303:THAL RS02705
gene id: 638303:THAL_RS02705
uniprot id: D3SPT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

638303:THAL RS04815
gene id: 638303:THAL_RS04815
uniprot id: D3SLE7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

638303:THAL RS00390
gene id: 638303:THAL_RS00390
uniprot id: D3SNI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

638303:THAL RS06015
gene id: 638303:THAL_RS06015
uniprot id: D3SM32
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

638303:THAL RS03460
gene id: 638303:THAL_RS03460
uniprot id: D3SQ83
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

638303:THAL RS02020
gene id: 638303:THAL_RS02020
uniprot id: D3SPF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

638303:THAL RS01250
gene id: 638303:THAL_RS01250
uniprot id: D3SP02
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS04820
gene id: 638303:THAL_RS04820
uniprot id: D3SLE8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

638303:THAL RS02445
gene id: 638303:THAL_RS02445
uniprot id: D3SPN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS07495
gene id: 638303:THAL_RS07495
uniprot id: D3SMX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS00090
gene id: 638303:THAL_RS00090
uniprot id: D3SNC0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

638303:THAL RS07465
gene id: 638303:THAL_RS07465
uniprot id: D3SMW9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

638303:THAL RS07480
gene id: 638303:THAL_RS07480
uniprot id: D3SMX2
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS01885
gene id: 638303:THAL_RS01885
uniprot id: D3SPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS01730
gene id: 638303:THAL_RS01730
uniprot id: D3SP96
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

638303:THAL RS03050
gene id: 638303:THAL_RS03050
uniprot id: D3SQ07
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

638303:THAL RS06945
gene id: 638303:THAL_RS06945
uniprot id: D3SML8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

638303:THAL RS03700
gene id: 638303:THAL_RS03700
uniprot id: D3SQD0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

638303:THAL RS03225
gene id: 638303:THAL_RS03225
uniprot id: D3SQ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

638303:THAL RS02695
gene id: 638303:THAL_RS02695
uniprot id: D3SPT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

638303:THAL RS02670
gene id: 638303:THAL_RS02670
uniprot id: D3SPT3
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS00450
gene id: 638303:THAL_RS00450
uniprot id: D3SNJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

638303:THAL RS01040
gene id: 638303:THAL_RS01040
uniprot id: D3SNW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

638303:THAL RS02040
gene id: 638303:THAL_RS02040
uniprot id: D3SPF9
names: Similarity
messages: Belongs to the P(II) protein family.

638303:THAL RS07910
gene id: 638303:THAL_RS07910
uniprot id: D3SN53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

638303:THAL RS07185
gene id: 638303:THAL_RS07185
uniprot id: D3SMR2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

638303:THAL RS00265
gene id: 638303:THAL_RS00265
uniprot id: D3SNF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

638303:THAL RS03825
gene id: 638303:THAL_RS03825
uniprot id: D3SQF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

638303:THAL RS00095
gene id: 638303:THAL_RS00095
uniprot id: D3SNC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

638303:THAL RS02890
gene id: 638303:THAL_RS02890
uniprot id: D3SPX6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

638303:THAL RS02880
gene id: 638303:THAL_RS02880
uniprot id: D3SPX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

638303:THAL RS05145
gene id: 638303:THAL_RS05145
uniprot id: D3SLL2
names: Similarity
messages: Belongs to the GARS family.

638303:THAL RS00305
gene id: 638303:THAL_RS00305
uniprot id: D3SNG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

638303:THAL RS01405
gene id: 638303:THAL_RS01405
uniprot id: D3SP32
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS01910
gene id: 638303:THAL_RS01910
uniprot id: D3SPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

638303:THAL RS00065
gene id: 638303:THAL_RS00065
uniprot id: D3SNB4
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

638303:THAL RS01085
gene id: 638303:THAL_RS01085
uniprot id: D3SNW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

638303:THAL RS06040
gene id: 638303:THAL_RS06040
uniprot id: D3SM36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

638303:THAL RS00950
gene id: 638303:THAL_RS00950
uniprot id: D3SNU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

638303:THAL RS05225
gene id: 638303:THAL_RS05225
uniprot id: D3SLM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

638303:THAL RS02680
gene id: 638303:THAL_RS02680
uniprot id: D3SPT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

638303:THAL RS05425
gene id: 638303:THAL_RS05425
uniprot id: D3SLR7
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS04275
gene id: 638303:THAL_RS04275
uniprot id: D3SL47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

638303:THAL RS03290
gene id: 638303:THAL_RS03290
uniprot id: D3SQ49
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

638303:THAL RS02315
gene id: 638303:THAL_RS02315
uniprot id: D3SPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

638303:THAL RS07335
gene id: 638303:THAL_RS07335
uniprot id: D3SMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

638303:THAL RS05760
gene id: 638303:THAL_RS05760
uniprot id: D3SLY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

638303:THAL RS05195
gene id: 638303:THAL_RS05195
uniprot id: D3SLM1
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03805
gene id: 638303:THAL_RS03805
uniprot id: D3SQF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

638303:THAL RS06375
gene id: 638303:THAL_RS06375
uniprot id: D3SMA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

638303:THAL RS00335
gene id: 638303:THAL_RS00335
uniprot id: D3SNG9
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

638303:THAL RS01370
gene id: 638303:THAL_RS01370
uniprot id: D3SP25
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS00275
gene id: 638303:THAL_RS00275
uniprot id: D3SNF7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

638303:THAL RS02895
gene id: 638303:THAL_RS02895
uniprot id: D3SPX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

638303:THAL RS03085
gene id: 638303:THAL_RS03085
uniprot id: D3SQ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

638303:THAL RS01415
gene id: 638303:THAL_RS01415
uniprot id: D3SP34
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

638303:THAL RS04170
gene id: 638303:THAL_RS04170
uniprot id: D3SL27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS07345
gene id: 638303:THAL_RS07345
uniprot id: D3SMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

638303:THAL RS04920
gene id: 638303:THAL_RS04920
uniprot id: D3SLG8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS06910
gene id: 638303:THAL_RS06910
uniprot id: D3SML0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

638303:THAL RS07435
gene id: 638303:THAL_RS07435
uniprot id: D3SMW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

638303:THAL RS07120
gene id: 638303:THAL_RS07120
uniprot id: D3SMP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

638303:THAL RS07430
gene id: 638303:THAL_RS07430
uniprot id: D3SMW2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

638303:THAL RS01050
gene id: 638303:THAL_RS01050
uniprot id: D3SNW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

638303:THAL RS04080
gene id: 638303:THAL_RS04080
uniprot id: D3SL09
names: Similarity
messages: Belongs to the RutC family.

638303:THAL RS02385
gene id: 638303:THAL_RS02385
uniprot id: D3SPM6
names: Similarity
messages: Belongs to the TrpF family.

638303:THAL RS07750
gene id: 638303:THAL_RS07750
uniprot id: D3SN23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

638303:THAL RS00660
gene id: 638303:THAL_RS00660
uniprot id: D3SNN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS01345
gene id: 638303:THAL_RS01345
uniprot id: D3SP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Membrane

638303:THAL RS00515
gene id: 638303:THAL_RS00515
uniprot id: D3SNK5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

638303:THAL RS00615
gene id: 638303:THAL_RS00615
uniprot id: D3SNM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

638303:THAL RS07800
gene id: 638303:THAL_RS07800
uniprot id: D3SN33
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

638303:THAL RS01635
gene id: 638303:THAL_RS01635
uniprot id: D3SP78
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

638303:THAL RS06590
gene id: 638303:THAL_RS06590
uniprot id: D3SME6
names: Similarity
messages: Belongs to the UPF0166 family.

638303:THAL RS01480
gene id: 638303:THAL_RS01480
uniprot id: D3SP47
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

638303:THAL RS01990
gene id: 638303:THAL_RS01990
uniprot id: D3SPE9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

638303:THAL RS01800
gene id: 638303:THAL_RS01800
uniprot id: D3SPB0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS06145
gene id: 638303:THAL_RS06145
uniprot id: D3SM57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS05650
gene id: 638303:THAL_RS05650
uniprot id: D3SLW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

638303:THAL RS06695
gene id: 638303:THAL_RS06695
uniprot id: D3SMG7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

638303:THAL RS06035
gene id: 638303:THAL_RS06035
uniprot id: D3SM35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

638303:THAL RS02970
gene id: 638303:THAL_RS02970
uniprot id: D3SPZ1
names: Subcellular Location Annotation
messages: Mitochondrion

638303:THAL RS06935
gene id: 638303:THAL_RS06935
uniprot id: D3SML6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

638303:THAL RS03820
gene id: 638303:THAL_RS03820
uniprot id: D3SQF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

638303:THAL RS01080
gene id: 638303:THAL_RS01080
uniprot id: D3SNW7
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

638303:THAL RS03725
gene id: 638303:THAL_RS03725
uniprot id: D3SQD5
names: Similarity
messages: Belongs to the TlyA family.

638303:THAL RS05275
gene id: 638303:THAL_RS05275
uniprot id: D3SLN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS04960
gene id: 638303:THAL_RS04960
uniprot id: D3SLH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

638303:THAL RS07965
gene id: 638303:THAL_RS07965
uniprot id: D3SN65
names: Similarity
messages: Belongs to the SCO1/2 family.

638303:THAL RS03300
gene id: 638303:THAL_RS03300
uniprot id: D3SQ51
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

638303:THAL RS02520
gene id: 638303:THAL_RS02520
uniprot id: D3SPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

638303:THAL RS04450
gene id: 638303:THAL_RS04450
uniprot id: D3SL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

638303:THAL RS02715
gene id: 638303:THAL_RS02715
uniprot id: D3SPU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS06705
gene id: 638303:THAL_RS06705
uniprot id: D3SMG9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

638303:THAL RS08005
gene id: 638303:THAL_RS08005
uniprot id: D3SN74
names: Similarity
messages: Belongs to the SCO1/2 family.

638303:THAL RS07960
gene id: 638303:THAL_RS07960
uniprot id: D3SN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

638303:THAL RS00150
gene id: 638303:THAL_RS00150
uniprot id: D3SND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

638303:THAL RS06175
gene id: 638303:THAL_RS06175
uniprot id: D3SM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS06165
gene id: 638303:THAL_RS06165
uniprot id: D3SM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

638303:THAL RS00895
gene id: 638303:THAL_RS00895
uniprot id: D3SNT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

638303:THAL RS03755
gene id: 638303:THAL_RS03755
uniprot id: D3SQE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

638303:THAL RS06135
gene id: 638303:THAL_RS06135
uniprot id: D3SM55
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

638303:THAL RS05180
gene id: 638303:THAL_RS05180
uniprot id: D3SLL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

638303:THAL RS05160
gene id: 638303:THAL_RS05160
uniprot id: D3SLL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS01425
gene id: 638303:THAL_RS01425
uniprot id: D3SP36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

638303:THAL RS00940
gene id: 638303:THAL_RS00940
uniprot id: D3SNT9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS04535
gene id: 638303:THAL_RS04535
uniprot id: D3SL95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

638303:THAL RS00215
gene id: 638303:THAL_RS00215
uniprot id: D3SNE5
names: Similarity
messages: Belongs to the bacterial secretin family.

638303:THAL RS07475
gene id: 638303:THAL_RS07475
uniprot id: D3SMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

638303:THAL RS02800
gene id: 638303:THAL_RS02800
uniprot id: D3SPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

638303:THAL RS01930
gene id: 638303:THAL_RS01930
uniprot id: D3SPD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

638303:THAL RS02375
gene id: 638303:THAL_RS02375
uniprot id: D3SPM4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

638303:THAL RS02580
gene id: 638303:THAL_RS02580
uniprot id: D3SPR6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

638303:THAL RS06485
gene id: 638303:THAL_RS06485
uniprot id: D3SMC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

638303:THAL RS06645
gene id: 638303:THAL_RS06645
uniprot id: D3SMF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

638303:THAL RS01900
gene id: 638303:THAL_RS01900
uniprot id: D3SPD0
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS04060
gene id: 638303:THAL_RS04060
uniprot id: D3SL05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

638303:THAL RS05280
gene id: 638303:THAL_RS05280
uniprot id: D3SLN8
names: Similarity
messages: Belongs to the DprA/Smf family.

638303:THAL RS07515
gene id: 638303:THAL_RS07515
uniprot id: D3SMX7
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS05045
gene id: 638303:THAL_RS05045
uniprot id: D3SLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

638303:THAL RS04735
gene id: 638303:THAL_RS04735
uniprot id: D3SLD1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

638303:THAL RS04640
gene id: 638303:THAL_RS04640
uniprot id: D3SLB1
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS04330
gene id: 638303:THAL_RS04330
uniprot id: D3SL56
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

638303:THAL RS01970
gene id: 638303:THAL_RS01970
uniprot id: D3SPE5
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03365
gene id: 638303:THAL_RS03365
uniprot id: D3SQ65
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

638303:THAL RS06565
gene id: 638303:THAL_RS06565
uniprot id: D3SME1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

638303:THAL RS06315
gene id: 638303:THAL_RS06315
uniprot id: D3SM92
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS06125
gene id: 638303:THAL_RS06125
uniprot id: D3SM53
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

638303:THAL RS02985
gene id: 638303:THAL_RS02985
uniprot id: D3SPZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

638303:THAL RS04570
gene id: 638303:THAL_RS04570
uniprot id: D3SLA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

638303:THAL RS06495
gene id: 638303:THAL_RS06495
uniprot id: D3SMC8
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS02565
gene id: 638303:THAL_RS02565
uniprot id: D3SPR3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

638303:THAL RS03110
gene id: 638303:THAL_RS03110
uniprot id: D3SQ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

638303:THAL RS03930
gene id: 638303:THAL_RS03930
uniprot id: D3SQH4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

638303:THAL RS01195
gene id: 638303:THAL_RS01195
uniprot id: D3SNZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS07420
gene id: 638303:THAL_RS07420
uniprot id: D3SMW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

638303:THAL RS06080
gene id: 638303:THAL_RS06080
uniprot id: D3SM44
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

638303:THAL RS03075
gene id: 638303:THAL_RS03075
uniprot id: D3SQ12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

638303:THAL RS01625
gene id: 638303:THAL_RS01625
uniprot id: D3SP76
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

638303:THAL RS02740
gene id: 638303:THAL_RS02740
uniprot id: D3SPU6
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03490
gene id: 638303:THAL_RS03490
uniprot id: D3SQ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

638303:THAL RS06770
gene id: 638303:THAL_RS06770
uniprot id: D3SMI2
names: PTM
messages: Binds 1 heme c group covalently per subunit.

638303:THAL RS05595
gene id: 638303:THAL_RS05595
uniprot id: D3SLV2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

638303:THAL RS05105
gene id: 638303:THAL_RS05105
uniprot id: D3SLK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

638303:THAL RS00510
gene id: 638303:THAL_RS00510
uniprot id: D3SNK4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

638303:THAL RS02330
gene id: 638303:THAL_RS02330
uniprot id: D3SPL5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

638303:THAL RS03245
gene id: 638303:THAL_RS03245
uniprot id: D3SQ40
names: Similarity
messages: Belongs to the ribF family.

638303:THAL RS04905
gene id: 638303:THAL_RS04905
uniprot id: D3SLG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

638303:THAL RS07425
gene id: 638303:THAL_RS07425
uniprot id: D3SMW1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

638303:THAL RS07675
gene id: 638303:THAL_RS07675
uniprot id: D3SN09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

638303:THAL RS06740
gene id: 638303:THAL_RS06740
uniprot id: D3SMH6
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS04635
gene id: 638303:THAL_RS04635
uniprot id: D3SLB0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

638303:THAL RS03890
gene id: 638303:THAL_RS03890
uniprot id: D3SQG8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

638303:THAL RS03775
gene id: 638303:THAL_RS03775
uniprot id: D3SQE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

638303:THAL RS05000
gene id: 638303:THAL_RS05000
uniprot id: D3SLI4
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03465
gene id: 638303:THAL_RS03465
uniprot id: D3SQ84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

638303:THAL RS06160
gene id: 638303:THAL_RS06160
uniprot id: D3SM60
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS02870
gene id: 638303:THAL_RS02870
uniprot id: D3SPX2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

638303:THAL RS03780
gene id: 638303:THAL_RS03780
uniprot id: D3SQE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

638303:THAL RS01875
gene id: 638303:THAL_RS01875
uniprot id: D3SPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS02435
gene id: 638303:THAL_RS02435
uniprot id: D3SPN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

638303:THAL RS06170
gene id: 638303:THAL_RS06170
uniprot id: D3SM62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS02960
gene id: 638303:THAL_RS02960
uniprot id: D3SPY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS07180
gene id: 638303:THAL_RS07180
uniprot id: D3SMR1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

638303:THAL RS05460
gene id: 638303:THAL_RS05460
uniprot id: D3SLS4
names: Similarity
messages: Belongs to the UPF0045 family.

638303:THAL RS07720
gene id: 638303:THAL_RS07720
uniprot id: D3SN17
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS06900
gene id: 638303:THAL_RS06900
uniprot id: D3SMK8
names: Similarity
messages: Belongs to the thioredoxin family.

638303:THAL RS06215
gene id: 638303:THAL_RS06215
uniprot id: D3SM71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS00365
gene id: 638303:THAL_RS00365
uniprot id: D3SNH5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS01760
gene id: 638303:THAL_RS01760
uniprot id: D3SPA2
names: Similarity
messages: Belongs to the aspartokinase family.

638303:THAL RS05320
gene id: 638303:THAL_RS05320
uniprot id: D3SLP6
names: Similarity
messages: Belongs to the HypD family.

638303:THAL RS00120
gene id: 638303:THAL_RS00120
uniprot id: D3SNC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

638303:THAL RS07540
gene id: 638303:THAL_RS07540
uniprot id: D3SMY2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

638303:THAL RS01215
gene id: 638303:THAL_RS01215
uniprot id: D3SNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

638303:THAL RS07330
gene id: 638303:THAL_RS07330
uniprot id: D3SMU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

638303:THAL RS07390
gene id: 638303:THAL_RS07390
uniprot id: D3SMV3
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS04720
gene id: 638303:THAL_RS04720
uniprot id: D3SLC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

638303:THAL RS01120
gene id: 638303:THAL_RS01120
uniprot id: D3SNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

638303:THAL RS08055
gene id: 638303:THAL_RS08055
uniprot id: D3SN84
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

638303:THAL RS07235
gene id: 638303:THAL_RS07235
uniprot id: D3SMS2
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS05885
gene id: 638303:THAL_RS05885
uniprot id: D3SM07
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

638303:THAL RS07730
gene id: 638303:THAL_RS07730
uniprot id: D3SN19
names: Similarity
messages: Belongs to the histone deacetylase family.

638303:THAL RS02110
gene id: 638303:THAL_RS02110
uniprot id: D3SPH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

638303:THAL RS03265
gene id: 638303:THAL_RS03265
uniprot id: D3SQ44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

638303:THAL RS03830
gene id: 638303:THAL_RS03830
uniprot id: D3SQF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

638303:THAL RS07380
gene id: 638303:THAL_RS07380
uniprot id: D3SMV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

638303:THAL RS01640
gene id: 638303:THAL_RS01640
uniprot id: D3SP79
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

638303:THAL RS08040
gene id: 638303:THAL_RS08040
uniprot id: D3SN81
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

638303:THAL RS01090
gene id: 638303:THAL_RS01090
uniprot id: D3SNW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

638303:THAL RS03705
gene id: 638303:THAL_RS03705
uniprot id: D3SQD1
names: Similarity
messages: Belongs to the peptidase S26 family.

638303:THAL RS05525
gene id: 638303:THAL_RS05525
uniprot id: D3SLT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

638303:THAL RS03535
gene id: 638303:THAL_RS03535
uniprot id: D3SQ97
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS06370
gene id: 638303:THAL_RS06370
uniprot id: D3SMA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

638303:THAL RS03385
gene id: 638303:THAL_RS03385
uniprot id: D3SQ69
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

638303:THAL RS01385
gene id: 638303:THAL_RS01385
uniprot id: D3SP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

638303:THAL RS05775
gene id: 638303:THAL_RS05775
uniprot id: D3SLY7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

638303:THAL RS06585
gene id: 638303:THAL_RS06585
uniprot id: D3SME5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

638303:THAL RS00835
gene id: 638303:THAL_RS00835
uniprot id: D3SNR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

638303:THAL RS07110
gene id: 638303:THAL_RS07110
uniprot id: D3SMP7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

638303:THAL RS03735
gene id: 638303:THAL_RS03735
uniprot id: D3SQD7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

638303:THAL RS04745
gene id: 638303:THAL_RS04745
uniprot id: D3SLD3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

638303:THAL RS04825
gene id: 638303:THAL_RS04825
uniprot id: D3SLE9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

638303:THAL RS03475
gene id: 638303:THAL_RS03475
uniprot id: D3SQ86
names: Similarity
messages: Belongs to the ClpA/ClpB family.

638303:THAL RS05125
gene id: 638303:THAL_RS05125
uniprot id: D3SLK8
names: Similarity
messages: Belongs to the archease family.

638303:THAL RS06295
gene id: 638303:THAL_RS06295
uniprot id: D3SM88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

638303:THAL RS06675
gene id: 638303:THAL_RS06675
uniprot id: D3SMG3
names: Similarity
messages: Belongs to the glutamine synthetase family.

638303:THAL RS02755
gene id: 638303:THAL_RS02755
uniprot id: D3SPU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

638303:THAL RS03470
gene id: 638303:THAL_RS03470
uniprot id: D3SQ85
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

638303:THAL RS01170
gene id: 638303:THAL_RS01170
uniprot id: D3SNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of 2 proteins (FliG, FliN) that might form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

638303:THAL RS00490
gene id: 638303:THAL_RS00490
uniprot id: D3SNK0
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS01270
gene id: 638303:THAL_RS01270
uniprot id: D3SP06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

638303:THAL RS00635
gene id: 638303:THAL_RS00635
uniprot id: D3SNM7
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

638303:THAL RS02805
gene id: 638303:THAL_RS02805
uniprot id: D3SPV9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

638303:THAL RS05635
gene id: 638303:THAL_RS05635
uniprot id: D3SLW0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

638303:THAL RS03100
gene id: 638303:THAL_RS03100
uniprot id: D3SQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

638303:THAL RS00400
gene id: 638303:THAL_RS00400
uniprot id: D3SNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

638303:THAL RS06500
gene id: 638303:THAL_RS06500
uniprot id: D3SMC9
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS00775
gene id: 638303:THAL_RS00775
uniprot id: D3SNQ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS06140
gene id: 638303:THAL_RS06140
uniprot id: D3SM56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS04490
gene id: 638303:THAL_RS04490
uniprot id: D3SL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

638303:THAL RS00840
gene id: 638303:THAL_RS00840
uniprot id: D3SNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

638303:THAL RS06825
gene id: 638303:THAL_RS06825
uniprot id: D3SMJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

638303:THAL RS06335
gene id: 638303:THAL_RS06335
uniprot id: D3SM96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

638303:THAL RS07545
gene id: 638303:THAL_RS07545
uniprot id: D3SMY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

638303:THAL RS01915
gene id: 638303:THAL_RS01915
uniprot id: D3SPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

638303:THAL RS00540
gene id: 638303:THAL_RS00540
uniprot id: D3SNL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

638303:THAL RS06330
gene id: 638303:THAL_RS06330
uniprot id: D3SM95
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

638303:THAL RS03145
gene id: 638303:THAL_RS03145
uniprot id: D3SQ26
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

638303:THAL RS01515
gene id: 638303:THAL_RS01515
uniprot id: D3SP54
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS06410
gene id: 638303:THAL_RS06410
uniprot id: D3SMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

638303:THAL RS02810
gene id: 638303:THAL_RS02810
uniprot id: D3SPW0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

638303:THAL RS04550
gene id: 638303:THAL_RS04550
uniprot id: D3SL98
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

638303:THAL RS03500
gene id: 638303:THAL_RS03500
uniprot id: D3SQ91
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

638303:THAL RS02685
gene id: 638303:THAL_RS02685
uniprot id: D3SPT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

638303:THAL RS01235
gene id: 638303:THAL_RS01235
uniprot id: D3SNZ8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

638303:THAL RS04530
gene id: 638303:THAL_RS04530
uniprot id: D3SL94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS08000
gene id: 638303:THAL_RS08000
uniprot id: D3SN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

638303:THAL RS08015
gene id: 638303:THAL_RS08015
uniprot id: D3SN76
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

638303:THAL RS02225
gene id: 638303:THAL_RS02225
uniprot id: D3SPJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

638303:THAL RS06020
gene id: 638303:THAL_RS06020
uniprot id: D3SM33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

638303:THAL RS03740
gene id: 638303:THAL_RS03740
uniprot id: D3SQD8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

638303:THAL RS00470
gene id: 638303:THAL_RS00470
uniprot id: D3SNJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

638303:THAL RS06520
gene id: 638303:THAL_RS06520
uniprot id: D3SMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

638303:THAL RS00245
gene id: 638303:THAL_RS00245
uniprot id: D3SNF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

638303:THAL RS07770
gene id: 638303:THAL_RS07770
uniprot id: D3SN27
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

638303:THAL RS05955
gene id: 638303:THAL_RS05955
uniprot id: D3SM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

638303:THAL RS02655
gene id: 638303:THAL_RS02655
uniprot id: D3SPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

638303:THAL RS03615
gene id: 638303:THAL_RS03615
uniprot id: D3SQB4
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS05455
gene id: 638303:THAL_RS05455
uniprot id: D3SLS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

638303:THAL RS02855
gene id: 638303:THAL_RS02855
uniprot id: D3SPW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

638303:THAL RS02140
gene id: 638303:THAL_RS02140
uniprot id: D3SPH8
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

638303:THAL RS01600
gene id: 638303:THAL_RS01600
uniprot id: D3SP71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

638303:THAL RS01805
gene id: 638303:THAL_RS01805
uniprot id: D3SPB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

638303:THAL RS02250
gene id: 638303:THAL_RS02250
uniprot id: D3SPJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

638303:THAL RS05550
gene id: 638303:THAL_RS05550
uniprot id: D3SLU3
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS05310
gene id: 638303:THAL_RS05310
uniprot id: D3SLP4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

638303:THAL RS01070
gene id: 638303:THAL_RS01070
uniprot id: D3SNW5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

638303:THAL RS00900
gene id: 638303:THAL_RS00900
uniprot id: D3SNT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

638303:THAL RS04310
gene id: 638303:THAL_RS04310
uniprot id: D3SL53
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

638303:THAL RS03660
gene id: 638303:THAL_RS03660
uniprot id: D3SQC3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.

638303:THAL RS00975
gene id: 638303:THAL_RS00975
uniprot id: D3SNU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

638303:THAL RS04200
gene id: 638303:THAL_RS04200
uniprot id: D3SL33
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

638303:THAL RS04895
gene id: 638303:THAL_RS04895
uniprot id: D3SLG3
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

638303:THAL RS05940
gene id: 638303:THAL_RS05940
uniprot id: D3SM17
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

638303:THAL RS07735
gene id: 638303:THAL_RS07735
uniprot id: D3SN20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS05085
gene id: 638303:THAL_RS05085
uniprot id: D3SLK0
names: Similarity
messages: Belongs to the peptidase M24B family.

638303:THAL RS04265
gene id: 638303:THAL_RS04265
uniprot id: D3SL45
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

638303:THAL RS02885
gene id: 638303:THAL_RS02885
uniprot id: D3SPX5
names: Similarity
messages: Belongs to the Skp family.

638303:THAL RS00435
gene id: 638303:THAL_RS00435
uniprot id: D3SNI9
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

638303:THAL RS02280
gene id: 638303:THAL_RS02280
uniprot id: D3SPK5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

638303:THAL RS00810
gene id: 638303:THAL_RS00810
uniprot id: D3SNR3
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

638303:THAL RS03795
gene id: 638303:THAL_RS03795
uniprot id: D3SQE9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

638303:THAL RS00445
gene id: 638303:THAL_RS00445
uniprot id: D3SNJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

638303:THAL RS07315
gene id: 638303:THAL_RS07315
uniprot id: D3SMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

638303:THAL RS08130
gene id: 638303:THAL_RS08130
uniprot id: D3SNA0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

638303:THAL RS05490
gene id: 638303:THAL_RS05490
uniprot id: D3SLT1
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS04900
gene id: 638303:THAL_RS04900
uniprot id: D3SLG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

638303:THAL RS02215
gene id: 638303:THAL_RS02215
uniprot id: D3SPJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS01880
gene id: 638303:THAL_RS01880
uniprot id: D3SPC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS04320
gene id: 638303:THAL_RS04320
uniprot id: D3SL54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

638303:THAL RS04105
gene id: 638303:THAL_RS04105
uniprot id: D3SL14
names: Similarity
messages: Belongs to the Nudix hydrolase family.

638303:THAL RS01895
gene id: 638303:THAL_RS01895
uniprot id: D3SPC9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

638303:THAL RS00380
gene id: 638303:THAL_RS00380
uniprot id: D3SNH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

638303:THAL RS02665
gene id: 638303:THAL_RS02665
uniprot id: D3SPT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

638303:THAL RS03670
gene id: 638303:THAL_RS03670
uniprot id: D3SQC5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

638303:THAL RS04855
gene id: 638303:THAL_RS04855
uniprot id: D3SLF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

638303:THAL RS07050
gene id: 638303:THAL_RS07050
uniprot id: D3SMN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS04965
gene id: 638303:THAL_RS04965
uniprot id: D3SLH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS03260
gene id: 638303:THAL_RS03260
uniprot id: D3SQ43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

638303:THAL RS03630
gene id: 638303:THAL_RS03630
uniprot id: D3SQB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

638303:THAL RS04425
gene id: 638303:THAL_RS04425
uniprot id: D3SL74
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

638303:THAL RS04470
gene id: 638303:THAL_RS04470
uniprot id: D3SL82
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

638303:THAL RS06550
gene id: 638303:THAL_RS06550
uniprot id: D3SMD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS04210
gene id: 638303:THAL_RS04210
uniprot id: D3SL34
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

638303:THAL RS03595
gene id: 638303:THAL_RS03595
uniprot id: D3SQB0
names: Similarity
messages: Belongs to the arginase family.

638303:THAL RS00600
gene id: 638303:THAL_RS00600
uniprot id: D3SNM0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

638303:THAL RS06525
gene id: 638303:THAL_RS06525
uniprot id: D3SMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

638303:THAL RS07710
gene id: 638303:THAL_RS07710
uniprot id: D3SN15
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS01055
gene id: 638303:THAL_RS01055
uniprot id: D3SNW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

638303:THAL RS07820
gene id: 638303:THAL_RS07820
uniprot id: D3SN37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BioW family.
messages: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
messages: Homodimer.

638303:THAL RS07200
gene id: 638303:THAL_RS07200
uniprot id: D3SMR5
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

638303:THAL RS01465
gene id: 638303:THAL_RS01465
uniprot id: D3SP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

638303:THAL RS01620
gene id: 638303:THAL_RS01620
uniprot id: D3SP75
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS01650
gene id: 638303:THAL_RS01650
uniprot id: D3SP81
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

638303:THAL RS01655
gene id: 638303:THAL_RS01655
uniprot id: D3SP82
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

638303:THAL RS01755
gene id: 638303:THAL_RS01755
uniprot id: D3SPA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

638303:THAL RS06200
gene id: 638303:THAL_RS06200
uniprot id: D3SM68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS00955
gene id: 638303:THAL_RS00955
uniprot id: D3SNU3
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS07905
gene id: 638303:THAL_RS07905
uniprot id: D3SN52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm

638303:THAL RS06575
gene id: 638303:THAL_RS06575
uniprot id: D3SME3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

638303:THAL RS03115
gene id: 638303:THAL_RS03115
uniprot id: D3SQ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

638303:THAL RS01770
gene id: 638303:THAL_RS01770
uniprot id: D3SPA4
names: Similarity
messages: Belongs to the UPF0102 family.

638303:THAL RS08070
gene id: 638303:THAL_RS08070
uniprot id: D3SN87
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

638303:THAL RS07550
gene id: 638303:THAL_RS07550
uniprot id: D3SMY4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS04270
gene id: 638303:THAL_RS04270
uniprot id: D3SL46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

638303:THAL RS02270
gene id: 638303:THAL_RS02270
uniprot id: D3SPK3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

638303:THAL RS00850
gene id: 638303:THAL_RS00850
uniprot id: D3SNS1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

638303:THAL RS04580
gene id: 638303:THAL_RS04580
uniprot id: D3SLA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

638303:THAL RS04300
gene id: 638303:THAL_RS04300
uniprot id: D3SL51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS01860
gene id: 638303:THAL_RS01860
uniprot id: D3SPC2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

638303:THAL RS06620
gene id: 638303:THAL_RS06620
uniprot id: D3SMF2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

638303:THAL RS05935
gene id: 638303:THAL_RS05935
uniprot id: D3SM16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

638303:THAL RS01870
gene id: 638303:THAL_RS01870
uniprot id: D3SPC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

638303:THAL RS01695
gene id: 638303:THAL_RS01695
uniprot id: D3SP90
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS05585
gene id: 638303:THAL_RS05585
uniprot id: D3SLV0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

638303:THAL RS06440
gene id: 638303:THAL_RS06440
uniprot id: D3SMB7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

638303:THAL RS06345
gene id: 638303:THAL_RS06345
uniprot id: D3SM98
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

638303:THAL RS00770
gene id: 638303:THAL_RS00770
uniprot id: D3SNQ5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

638303:THAL RS06540
gene id: 638303:THAL_RS06540
uniprot id: D3SMD6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

638303:THAL RS01545
gene id: 638303:THAL_RS01545
uniprot id: D3SP60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

638303:THAL RS00590
gene id: 638303:THAL_RS00590
uniprot id: D3SNL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

638303:THAL RS02025
gene id: 638303:THAL_RS02025
uniprot id: D3SPF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

638303:THAL RS02760
gene id: 638303:THAL_RS02760
uniprot id: D3SPV0
names: Similarity
messages: Belongs to the LOG family.

638303:THAL RS00920
gene id: 638303:THAL_RS00920
uniprot id: D3SNT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

638303:THAL RS00855
gene id: 638303:THAL_RS00855
uniprot id: D3SNS2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

638303:THAL RS01485
gene id: 638303:THAL_RS01485
uniprot id: D3SP48
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

638303:THAL RS06580
gene id: 638303:THAL_RS06580
uniprot id: D3SME4
names: Similarity
messages: Belongs to the UPF0166 family.

638303:THAL RS07530
gene id: 638303:THAL_RS07530
uniprot id: D3SMY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

638303:THAL RS05790
gene id: 638303:THAL_RS05790
uniprot id: D3SLZ0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

638303:THAL RS07025
gene id: 638303:THAL_RS07025
uniprot id: D3SMN4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS06445
gene id: 638303:THAL_RS06445
uniprot id: D3SMB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

638303:THAL RS06920
gene id: 638303:THAL_RS06920
uniprot id: D3SML3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS03065
gene id: 638303:THAL_RS03065
uniprot id: D3SQ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

638303:THAL RS06180
gene id: 638303:THAL_RS06180
uniprot id: D3SM64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS04870
gene id: 638303:THAL_RS04870
uniprot id: D3SLF8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

638303:THAL RS06240
gene id: 638303:THAL_RS06240
uniprot id: D3SM77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

638303:THAL RS02135
gene id: 638303:THAL_RS02135
uniprot id: D3SPH7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

638303:THAL RS04390
gene id: 638303:THAL_RS04390
uniprot id: D3SL67
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

638303:THAL RS02085
gene id: 638303:THAL_RS02085
uniprot id: D3SPG8
names: Similarity
messages: Belongs to the AOR/FOR family.

638303:THAL RS03585
gene id: 638303:THAL_RS03585
uniprot id: D3SQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

638303:THAL RS03970
gene id: 638303:THAL_RS03970
uniprot id: D3SQI2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

638303:THAL RS03925
gene id: 638303:THAL_RS03925
uniprot id: D3SQH3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

638303:THAL RS01540
gene id: 638303:THAL_RS01540
uniprot id: D3SP59
names: Similarity
messages: Belongs to the SfsA family.

638303:THAL RS00965
gene id: 638303:THAL_RS00965
uniprot id: D3SNU5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

638303:THAL RS02955
gene id: 638303:THAL_RS02955
uniprot id: D3SPY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

638303:THAL RS03575
gene id: 638303:THAL_RS03575
uniprot id: D3SQA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

638303:THAL RS01790
gene id: 638303:THAL_RS01790
uniprot id: D3SPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

638303:THAL RS07060
gene id: 638303:THAL_RS07060
uniprot id: D3SMP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

638303:THAL RS07950
gene id: 638303:THAL_RS07950
uniprot id: D3SN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

638303:THAL RS05735
gene id: 638303:THAL_RS05735
uniprot id: D3SLY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

638303:THAL RS05115
gene id: 638303:THAL_RS05115
uniprot id: D3SLK6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

638303:THAL RS01005
gene id: 638303:THAL_RS01005
uniprot id: D3SNV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

638303:THAL RS06290
gene id: 638303:THAL_RS06290
uniprot id: D3SM87
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

638303:THAL RS00080
gene id: 638303:THAL_RS00080
uniprot id: D3SNB7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

638303:THAL RS04375
gene id: 638303:THAL_RS04375
uniprot id: D3SL64
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

638303:THAL RS04280
gene id: 638303:THAL_RS04280
uniprot id: D3SL48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

638303:THAL RS00355
gene id: 638303:THAL_RS00355
uniprot id: D3SNH3
names: Similarity
messages: Belongs to the UPF0758 family.

638303:THAL RS06065
gene id: 638303:THAL_RS06065
uniprot id: D3SM41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

638303:THAL RS03910
gene id: 638303:THAL_RS03910
uniprot id: D3SQH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

638303:THAL RS04710
gene id: 638303:THAL_RS04710
uniprot id: D3SLC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

638303:THAL RS03680
gene id: 638303:THAL_RS03680
uniprot id: D3SQC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

638303:THAL RS08160
gene id: 638303:THAL_RS08160
uniprot id: D3SNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

638303:THAL RS02105
gene id: 638303:THAL_RS02105
uniprot id: D3SPH2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

638303:THAL RS07845
gene id: 638303:THAL_RS07845
uniprot id: D3SN40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Periplasm

638303:THAL RS01290
gene id: 638303:THAL_RS01290
uniprot id: D3SP10
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

638303:THAL RS05605
gene id: 638303:THAL_RS05605
uniprot id: D3SLV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

638303:THAL RS04845
gene id: 638303:THAL_RS04845
uniprot id: D3SLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

638303:THAL RS03090
gene id: 638303:THAL_RS03090
uniprot id: D3SQ15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

638303:THAL RS05670
gene id: 638303:THAL_RS05670
uniprot id: D3SLW7
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

638303:THAL RS07865
gene id: 638303:THAL_RS07865
uniprot id: D3SN44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

638303:THAL RS07350
gene id: 638303:THAL_RS07350
uniprot id: D3SMU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

638303:THAL RS07670
gene id: 638303:THAL_RS07670
uniprot id: D3SN08
names: Similarity
messages: Belongs to the RecJ family.

638303:THAL RS04675
gene id: 638303:THAL_RS04675
uniprot id: D3SLB9
names: Similarity
messages: Belongs to the PGI/PMI family.

638303:THAL RS02065
gene id: 638303:THAL_RS02065
uniprot id: D3SPG4
names: Similarity
messages: Belongs to the NifZ family.

638303:THAL RS06670
gene id: 638303:THAL_RS06670
uniprot id: D3SMG2
names: Similarity
messages: Belongs to the P(II) protein family.

638303:THAL RS05290
gene id: 638303:THAL_RS05290
uniprot id: D3SLP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

638303:THAL RS03380
gene id: 638303:THAL_RS03380
uniprot id: D3SQ68
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

638303:THAL RS01190
gene id: 638303:THAL_RS01190
uniprot id: D3SNY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

638303:THAL RS03055
gene id: 638303:THAL_RS03055
uniprot id: D3SQ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

638303:THAL RS02845
gene id: 638303:THAL_RS02845
uniprot id: D3SPW7
names: Similarity
messages: Belongs to the peptidase U62 family.

638303:THAL RS01825
gene id: 638303:THAL_RS01825
uniprot id: D3SPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

638303:THAL RS06925
gene id: 638303:THAL_RS06925
uniprot id: D3SML4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

638303:THAL RS01135
gene id: 638303:THAL_RS01135
uniprot id: D3SNX8
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS07370
gene id: 638303:THAL_RS07370
uniprot id: D3SMU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

638303:THAL RS05680
gene id: 638303:THAL_RS05680
uniprot id: D3SLW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

638303:THAL RS02230
gene id: 638303:THAL_RS02230
uniprot id: D3SPJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

638303:THAL RS00780
gene id: 638303:THAL_RS00780
uniprot id: D3SNQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

638303:THAL RS02875
gene id: 638303:THAL_RS02875
uniprot id: D3SPX3
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS00650
gene id: 638303:THAL_RS00650
uniprot id: D3SNN1
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS01685
gene id: 638303:THAL_RS01685
uniprot id: D3SP88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

638303:THAL RS06225
gene id: 638303:THAL_RS06225
uniprot id: D3SM74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

638303:THAL RS05390
gene id: 638303:THAL_RS05390
uniprot id: D3SLR0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

638303:THAL RS03480
gene id: 638303:THAL_RS03480
uniprot id: D3SQ87
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

638303:THAL RS02730
gene id: 638303:THAL_RS02730
uniprot id: D3SPU4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

638303:THAL RS03315
gene id: 638303:THAL_RS03315
uniprot id: D3SQ54
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

638303:THAL RS04795
gene id: 638303:THAL_RS04795
uniprot id: D3SLE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

638303:THAL RS08020
gene id: 638303:THAL_RS08020
uniprot id: D3SN77
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS03080
gene id: 638303:THAL_RS03080
uniprot id: D3SQ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

638303:THAL RS04215
gene id: 638303:THAL_RS04215
uniprot id: D3SL35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

638303:THAL RS00160
gene id: 638303:THAL_RS00160
uniprot id: D3SND4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

638303:THAL RS07520
gene id: 638303:THAL_RS07520
uniprot id: D3SMX8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

638303:THAL RS01775
gene id: 638303:THAL_RS01775
uniprot id: D3SPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

638303:THAL RS05090
gene id: 638303:THAL_RS05090
uniprot id: D3SLK1
names: Similarity
messages: Belongs to the sigma-54 factor family.

638303:THAL RS03750
gene id: 638303:THAL_RS03750
uniprot id: D3SQE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

638303:THAL RS05295
gene id: 638303:THAL_RS05295
uniprot id: D3SLP1
names: Similarity
messages: Belongs to the GSP E family.

638303:THAL RS00725
gene id: 638303:THAL_RS00725
uniprot id: D3SNP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

638303:THAL RS03765
gene id: 638303:THAL_RS03765
uniprot id: D3SQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

638303:THAL RS00880
gene id: 638303:THAL_RS00880
uniprot id: D3SNS7
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03400
gene id: 638303:THAL_RS03400
uniprot id: D3SQ72
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

638303:THAL RS04420
gene id: 638303:THAL_RS04420
uniprot id: D3SL73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

638303:THAL RS05415
gene id: 638303:THAL_RS05415
uniprot id: D3SLR5
names: Similarity
messages: Belongs to the universal stress protein A family.

638303:THAL RS00240
gene id: 638303:THAL_RS00240
uniprot id: D3SNF0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

638303:THAL RS07695
gene id: 638303:THAL_RS07695
uniprot id: D3SN12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

638303:THAL RS04055
gene id: 638303:THAL_RS04055
uniprot id: D3SL04
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

638303:THAL RS06455
gene id: 638303:THAL_RS06455
uniprot id: D3SMC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

638303:THAL RS02710
gene id: 638303:THAL_RS02710
uniprot id: D3SPU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS03395
gene id: 638303:THAL_RS03395
uniprot id: D3SQ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

638303:THAL RS04575
gene id: 638303:THAL_RS04575
uniprot id: D3SLA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

638303:THAL RS00800
gene id: 638303:THAL_RS00800
uniprot id: D3SNR1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS04515
gene id: 638303:THAL_RS04515
uniprot id: D3SL91
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

638303:THAL RS07455
gene id: 638303:THAL_RS07455
uniprot id: D3SMW7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

638303:THAL RS05950
gene id: 638303:THAL_RS05950
uniprot id: D3SM19
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

638303:THAL RS04325
gene id: 638303:THAL_RS04325
uniprot id: D3SL55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

638303:THAL RS00375
gene id: 638303:THAL_RS00375
uniprot id: D3SNH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

638303:THAL RS05255
gene id: 638303:THAL_RS05255
uniprot id: D3SLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

638303:THAL RS03045
gene id: 638303:THAL_RS03045
uniprot id: D3SQ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

638303:THAL RS01185
gene id: 638303:THAL_RS01185
uniprot id: D3SNY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

638303:THAL RS01725
gene id: 638303:THAL_RS01725
uniprot id: D3SP95
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

638303:THAL RS00330
gene id: 638303:THAL_RS00330
uniprot id: D3SNG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

638303:THAL RS07860
gene id: 638303:THAL_RS07860
uniprot id: D3SN43
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

638303:THAL RS06415
gene id: 638303:THAL_RS06415
uniprot id: D3SMB2
names: Similarity
messages: Belongs to the MoaD family.

638303:THAL RS04665
gene id: 638303:THAL_RS04665
uniprot id: D3SLB7
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS05020
gene id: 638303:THAL_RS05020
uniprot id: D3SLI8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

638303:THAL RS08035
gene id: 638303:THAL_RS08035
uniprot id: D3SN80
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

638303:THAL RS00500
gene id: 638303:THAL_RS00500
uniprot id: D3SNK2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

638303:THAL RS02425
gene id: 638303:THAL_RS02425
uniprot id: D3SPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

638303:THAL RS06190
gene id: 638303:THAL_RS06190
uniprot id: D3SM66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

638303:THAL RS00815
gene id: 638303:THAL_RS00815
uniprot id: D3SNR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

638303:THAL RS03855
gene id: 638303:THAL_RS03855
uniprot id: D3SQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SoxA family.
messages: Periplasm

638303:THAL RS07440
gene id: 638303:THAL_RS07440
uniprot id: D3SMW4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

638303:THAL RS05970
gene id: 638303:THAL_RS05970
uniprot id: D3SM23
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS03570
gene id: 638303:THAL_RS03570
uniprot id: D3SQA4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

638303:THAL RS06465
gene id: 638303:THAL_RS06465
uniprot id: D3SMC2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

638303:THAL RS03920
gene id: 638303:THAL_RS03920
uniprot id: D3SQH2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

638303:THAL RS07955
gene id: 638303:THAL_RS07955
uniprot id: D3SN63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

638303:THAL RS05725
gene id: 638303:THAL_RS05725
uniprot id: D3SLX8
names: Similarity
messages: Belongs to the HepT RNase toxin family.

638303:THAL RS07790
gene id: 638303:THAL_RS07790
uniprot id: D3SN31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

638303:THAL RS06470
gene id: 638303:THAL_RS06470
uniprot id: D3SMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

638303:THAL RS05220
gene id: 638303:THAL_RS05220
uniprot id: D3SLM6
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

638303:THAL RS03010
gene id: 638303:THAL_RS03010
uniprot id: D3SQ00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

638303:THAL RS05995
gene id: 638303:THAL_RS05995
uniprot id: D3SM28
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

638303:THAL RS05375
gene id: 638303:THAL_RS05375
uniprot id: D3SLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

638303:THAL RS06400
gene id: 638303:THAL_RS06400
uniprot id: D3SMA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

638303:THAL RS03205
gene id: 638303:THAL_RS03205
uniprot id: D3SQ32
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS01595
gene id: 638303:THAL_RS01595
uniprot id: D3SP70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

638303:THAL RS07460
gene id: 638303:THAL_RS07460
uniprot id: D3SMW8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS03425
gene id: 638303:THAL_RS03425
uniprot id: D3SQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

638303:THAL RS02585
gene id: 638303:THAL_RS02585
uniprot id: D3SPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

638303:THAL RS05345
gene id: 638303:THAL_RS05345
uniprot id: D3SLQ1
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS05465
gene id: 638303:THAL_RS05465
uniprot id: D3SLS5
names: Similarity
messages: Belongs to the peptidase S16 family.

638303:THAL RS03770
gene id: 638303:THAL_RS03770
uniprot id: D3SQE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

638303:THAL RS01380
gene id: 638303:THAL_RS01380
uniprot id: D3SP27
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

638303:THAL RS01455
gene id: 638303:THAL_RS01455
uniprot id: D3SP42
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS07485
gene id: 638303:THAL_RS07485
uniprot id: D3SMX3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS07215
gene id: 638303:THAL_RS07215
uniprot id: D3SMR8
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

638303:THAL RS01810
gene id: 638303:THAL_RS01810
uniprot id: D3SPB2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

638303:THAL RS00715
gene id: 638303:THAL_RS00715
uniprot id: D3SNP4
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

638303:THAL RS06660
gene id: 638303:THAL_RS06660
uniprot id: D3SMG0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

638303:THAL RS01935
gene id: 638303:THAL_RS01935
uniprot id: D3SPD7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS06045
gene id: 638303:THAL_RS06045
uniprot id: D3SM37
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

638303:THAL RS03790
gene id: 638303:THAL_RS03790
uniprot id: D3SQE8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

638303:THAL RS03405
gene id: 638303:THAL_RS03405
uniprot id: D3SQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

638303:THAL RS07500
gene id: 638303:THAL_RS07500
uniprot id: D3SMX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

638303:THAL RS00640
gene id: 638303:THAL_RS00640
uniprot id: D3SNM8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

638303:THAL RS00820
gene id: 638303:THAL_RS00820
uniprot id: D3SNR5
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.

638303:THAL RS04175
gene id: 638303:THAL_RS04175
uniprot id: D3SL28
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS07895
gene id: 638303:THAL_RS07895
uniprot id: D3SN50
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

638303:THAL RS00570
gene id: 638303:THAL_RS00570
uniprot id: D3SNL6
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

638303:THAL RS02420
gene id: 638303:THAL_RS02420
uniprot id: D3SPN3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

638303:THAL RS07355
gene id: 638303:THAL_RS07355
uniprot id: D3SMU6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

638303:THAL RS03270
gene id: 638303:THAL_RS03270
uniprot id: D3SQ45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

638303:THAL RS04085
gene id: 638303:THAL_RS04085
uniprot id: D3SL10
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

638303:THAL RS03965
gene id: 638303:THAL_RS03965
uniprot id: D3SQI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

638303:THAL RS04980
gene id: 638303:THAL_RS04980
uniprot id: D3SLI0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

638303:THAL RS07900
gene id: 638303:THAL_RS07900
uniprot id: D3SN51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

638303:THAL RS00485
gene id: 638303:THAL_RS00485
uniprot id: D3SNJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

638303:THAL RS05240
gene id: 638303:THAL_RS05240
uniprot id: D3SLN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

638303:THAL RS03390
gene id: 638303:THAL_RS03390
uniprot id: D3SQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

638303:THAL RS03125
gene id: 638303:THAL_RS03125
uniprot id: D3SQ22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

638303:THAL RS07935
gene id: 638303:THAL_RS07935
uniprot id: D3SN59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS06185
gene id: 638303:THAL_RS06185
uniprot id: D3SM65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

638303:THAL RS01260
gene id: 638303:THAL_RS01260
uniprot id: D3SP04
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

638303:THAL RS03220
gene id: 638303:THAL_RS03220
uniprot id: D3SQ35
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

638303:THAL RS03555
gene id: 638303:THAL_RS03555
uniprot id: D3SQA1
names: Similarity
messages: Belongs to the CFA/CMAS family.

638303:THAL RS03600
gene id: 638303:THAL_RS03600
uniprot id: D3SQA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

638303:THAL RS01610
gene id: 638303:THAL_RS01610
uniprot id: D3SP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

638303:THAL RS01745
gene id: 638303:THAL_RS01745
uniprot id: D3SP99
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

638303:THAL RS01060
gene id: 638303:THAL_RS01060
uniprot id: D3SNW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

638303:THAL RS05520
gene id: 638303:THAL_RS05520
uniprot id: D3SLT7
names: Similarity
messages: Belongs to the peptidase S41A family.

638303:THAL RS00805
gene id: 638303:THAL_RS00805
uniprot id: D3SNR2
names: Similarity
messages: Belongs to the CarB family.

638303:THAL RS00105
gene id: 638303:THAL_RS00105
uniprot id: D3SNC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

638303:THAL RS00315
gene id: 638303:THAL_RS00315
uniprot id: D3SNG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

638303:THAL RS03170
gene id: 638303:THAL_RS03170
uniprot id: D3SQ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

638303:THAL RS04685
gene id: 638303:THAL_RS04685
uniprot id: D3SLC1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

638303:THAL RS02745
gene id: 638303:THAL_RS02745
uniprot id: D3SPU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

638303:THAL RS04715
gene id: 638303:THAL_RS04715
uniprot id: D3SLC7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

638303:THAL RS02060
gene id: 638303:THAL_RS02060
uniprot id: D3SPG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

638303:THAL RS06130
gene id: 638303:THAL_RS06130
uniprot id: D3SM54
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

638303:THAL RS04050
gene id: 638303:THAL_RS04050
uniprot id: D3SL03
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

638303:THAL RS03140
gene id: 638303:THAL_RS03140
uniprot id: D3SQ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

638303:THAL RS01230
gene id: 638303:THAL_RS01230
uniprot id: D3SNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

638303:THAL RS05150
gene id: 638303:THAL_RS05150
uniprot id: D3SLL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

638303:THAL RS01780
gene id: 638303:THAL_RS01780
uniprot id: D3SPA6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

638303:THAL RS07645
gene id: 638303:THAL_RS07645
uniprot id: D3SN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

638303:THAL RS07000
gene id: 638303:THAL_RS07000
uniprot id: D3SMM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

638303:THAL RS06280
gene id: 638303:THAL_RS06280
uniprot id: D3SM85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS04525
gene id: 638303:THAL_RS04525
uniprot id: D3SL93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

638303:THAL RS04505
gene id: 638303:THAL_RS04505
uniprot id: D3SL89
names: Similarity
messages: Belongs to the CutA family.

638303:THAL RS07490
gene id: 638303:THAL_RS07490
uniprot id: D3SMX4
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS05570
gene id: 638303:THAL_RS05570
uniprot id: D3SLU7
names: Similarity
messages: Belongs to the class-I fumarase family.

638303:THAL RS06070
gene id: 638303:THAL_RS06070
uniprot id: D3SM42
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

638303:THAL RS03060
gene id: 638303:THAL_RS03060
uniprot id: D3SQ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

638303:THAL RS05025
gene id: 638303:THAL_RS05025
uniprot id: D3SLI9
names: Similarity
messages: Belongs to the glutamate synthase family.

638303:THAL RS01960
gene id: 638303:THAL_RS01960
uniprot id: D3SPE2
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03445
gene id: 638303:THAL_RS03445
uniprot id: D3SQ80
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

638303:THAL RS04660
gene id: 638303:THAL_RS04660
uniprot id: D3SLB6
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

638303:THAL RS04025
gene id: 638303:THAL_RS04025
uniprot id: D3SL00
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS05710
gene id: 638303:THAL_RS05710
uniprot id: D3SLX5
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS06715
gene id: 638303:THAL_RS06715
uniprot id: D3SMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

638303:THAL RS04765
gene id: 638303:THAL_RS04765
uniprot id: D3SLD7
names: Similarity
messages: Belongs to the MotB family.

638303:THAL RS03155
gene id: 638303:THAL_RS03155
uniprot id: D3SQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

638303:THAL RS02010
gene id: 638303:THAL_RS02010
uniprot id: D3SPF3
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

638303:THAL RS03105
gene id: 638303:THAL_RS03105
uniprot id: D3SQ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

638303:THAL RS06095
gene id: 638303:THAL_RS06095
uniprot id: D3SM47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

638303:THAL RS05495
gene id: 638303:THAL_RS05495
uniprot id: D3SLT2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

638303:THAL RS05405
gene id: 638303:THAL_RS05405
uniprot id: D3SLR3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

638303:THAL RS01430
gene id: 638303:THAL_RS01430
uniprot id: D3SP37
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

638303:THAL RS04370
gene id: 638303:THAL_RS04370
uniprot id: D3SL63
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS00690
gene id: 638303:THAL_RS00690
uniprot id: D3SNN9
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS02400
gene id: 638303:THAL_RS02400
uniprot id: D3SPM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

638303:THAL RS02815
gene id: 638303:THAL_RS02815
uniprot id: D3SPW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS01395
gene id: 638303:THAL_RS01395
uniprot id: D3SP30
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

638303:THAL RS00645
gene id: 638303:THAL_RS00645
uniprot id: D3SNN0
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS07745
gene id: 638303:THAL_RS07745
uniprot id: D3SN22
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

638303:THAL RS00875
gene id: 638303:THAL_RS00875
uniprot id: D3SNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

638303:THAL RS06810
gene id: 638303:THAL_RS06810
uniprot id: D3SMJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

638303:THAL RS05040
gene id: 638303:THAL_RS05040
uniprot id: D3SLJ2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

638303:THAL RS02335
gene id: 638303:THAL_RS02335
uniprot id: D3SPL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS03015
gene id: 638303:THAL_RS03015
uniprot id: D3SQ01
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

638303:THAL RS02405
gene id: 638303:THAL_RS02405
uniprot id: D3SPN0
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS06990
gene id: 638303:THAL_RS06990
uniprot id: D3SMM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

638303:THAL RS02310
gene id: 638303:THAL_RS02310
uniprot id: D3SPL1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

638303:THAL RS00050
gene id: 638303:THAL_RS00050
uniprot id: D3SNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

638303:THAL RS06515
gene id: 638303:THAL_RS06515
uniprot id: D3SMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

638303:THAL RS03875
gene id: 638303:THAL_RS03875
uniprot id: D3SQG5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

638303:THAL RS01500
gene id: 638303:THAL_RS01500
uniprot id: D3SP51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

638303:THAL RS03130
gene id: 638303:THAL_RS03130
uniprot id: D3SQ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

638303:THAL RS02320
gene id: 638303:THAL_RS02320
uniprot id: D3SPL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

638303:THAL RS01365
gene id: 638303:THAL_RS01365
uniprot id: D3SP24
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

638303:THAL RS01785
gene id: 638303:THAL_RS01785
uniprot id: D3SPA7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

638303:THAL RS04655
gene id: 638303:THAL_RS04655
uniprot id: D3SLB4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

638303:THAL RS04145
gene id: 638303:THAL_RS04145
uniprot id: D3SL22
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

638303:THAL RS03685
gene id: 638303:THAL_RS03685
uniprot id: D3SQC7
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

638303:THAL RS01335
gene id: 638303:THAL_RS01335
uniprot id: D3SP19
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

638303:THAL RS07160
gene id: 638303:THAL_RS07160
uniprot id: D3SMQ7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

638303:THAL RS05890
gene id: 638303:THAL_RS05890
uniprot id: D3SM08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

638303:THAL RS01700
gene id: 638303:THAL_RS01700
uniprot id: D3SP91
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

638303:THAL RS05685
gene id: 638303:THAL_RS05685
uniprot id: D3SLX0
names: Similarity
messages: Belongs to the GSP E family.

638303:THAL RS01030
gene id: 638303:THAL_RS01030
uniprot id: D3SNV8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

638303:THAL RS01015
gene id: 638303:THAL_RS01015
uniprot id: D3SNV5
names: Similarity
messages: Belongs to the PstS family.

638303:THAL RS00865
gene id: 638303:THAL_RS00865
uniprot id: D3SNS4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

638303:THAL RS02050
gene id: 638303:THAL_RS02050
uniprot id: D3SPG1
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

638303:THAL RS01350
gene id: 638303:THAL_RS01350
uniprot id: D3SP22
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

638303:THAL RS00825
gene id: 638303:THAL_RS00825
uniprot id: D3SNR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

638303:THAL RS05640
gene id: 638303:THAL_RS05640
uniprot id: D3SLW1
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

638303:THAL RS06325
gene id: 638303:THAL_RS06325
uniprot id: D3SM94
names: Similarity
messages: Belongs to the disproportionating enzyme family.

638303:THAL RS05395
gene id: 638303:THAL_RS05395
uniprot id: D3SLR1
names: Similarity
messages: Belongs to the TrpC family.

638303:THAL RS02630
gene id: 638303:THAL_RS02630
uniprot id: D3SPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

638303:THAL RS04770
gene id: 638303:THAL_RS04770
uniprot id: D3SLD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

638303:THAL RS00730
gene id: 638303:THAL_RS00730
uniprot id: D3SNP7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

638303:THAL RS07155
gene id: 638303:THAL_RS07155
uniprot id: D3SMQ6
names: Similarity
messages: Belongs to the peptidase A31 family.

638303:THAL RS02780
gene id: 638303:THAL_RS02780
uniprot id: D3SPV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

638303:THAL RS07635
gene id: 638303:THAL_RS07635
uniprot id: D3SN01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS03095
gene id: 638303:THAL_RS03095
uniprot id: D3SQ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

638303:THAL RS01925
gene id: 638303:THAL_RS01925
uniprot id: D3SPD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

638303:THAL RS05965
gene id: 638303:THAL_RS05965
uniprot id: D3SM22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

638303:THAL RS00255
gene id: 638303:THAL_RS00255
uniprot id: D3SNF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

638303:THAL RS07220
gene id: 638303:THAL_RS07220
uniprot id: D3SMR9
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS05005
gene id: 638303:THAL_RS05005
uniprot id: D3SLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

638303:THAL RS05470
gene id: 638303:THAL_RS05470
uniprot id: D3SLS6
names: Similarity
messages: Belongs to the fabD family.

638303:THAL RS04405
gene id: 638303:THAL_RS04405
uniprot id: D3SL70
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

638303:THAL RS03590
gene id: 638303:THAL_RS03590
uniprot id: D3SQA9
names: Subcellular Location Annotation
messages: Periplasm

638303:THAL RS01255
gene id: 638303:THAL_RS01255
uniprot id: D3SP03
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-52 and Arg-55) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

638303:THAL RS05055
gene id: 638303:THAL_RS05055
uniprot id: D3SLJ5
names: Similarity
messages: Belongs to the UPF0047 family.

638303:THAL RS02615
gene id: 638303:THAL_RS02615
uniprot id: D3SPS2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

638303:THAL RS03415
gene id: 638303:THAL_RS03415
uniprot id: D3SQ75
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

638303:THAL RS06355
gene id: 638303:THAL_RS06355
uniprot id: D3SMA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

638303:THAL RS06875
gene id: 638303:THAL_RS06875
uniprot id: D3SMK3
names: Similarity
messages: Belongs to the histone deacetylase family.

638303:THAL RS06210
gene id: 638303:THAL_RS06210
uniprot id: D3SM70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

638303:THAL RS02275
gene id: 638303:THAL_RS02275
uniprot id: D3SPK4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

638303:THAL RS03030
gene id: 638303:THAL_RS03030
uniprot id: D3SQ03
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

638303:THAL RS03135
gene id: 638303:THAL_RS03135
uniprot id: D3SQ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

638303:THAL RS05170
gene id: 638303:THAL_RS05170
uniprot id: D3SLL7
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS06430
gene id: 638303:THAL_RS06430
uniprot id: D3SMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

638303:THAL RS05095
gene id: 638303:THAL_RS05095
uniprot id: D3SLK2
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS06450
gene id: 638303:THAL_RS06450
uniprot id: D3SMB9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

638303:THAL RS02265
gene id: 638303:THAL_RS02265
uniprot id: D3SPK2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

638303:THAL RS03845
gene id: 638303:THAL_RS03845
uniprot id: D3SQF9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

638303:THAL RS00320
gene id: 638303:THAL_RS00320
uniprot id: D3SNG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

638303:THAL RS06260
gene id: 638303:THAL_RS06260
uniprot id: D3SM81
names: Similarity
messages: Belongs to the SAICAR synthetase family.

638303:THAL RS00480
gene id: 638303:THAL_RS00480
uniprot id: D3SNJ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

638303:THAL RS00475
gene id: 638303:THAL_RS00475
uniprot id: D3SNJ7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

638303:THAL RS02820
gene id: 638303:THAL_RS02820
uniprot id: D3SPW2
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

638303:THAL RS00530
gene id: 638303:THAL_RS00530
uniprot id: D3SNK8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

638303:THAL RS03915
gene id: 638303:THAL_RS03915
uniprot id: D3SQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

638303:THAL RS07680
gene id: 638303:THAL_RS07680
uniprot id: D3SN10
names: Similarity
messages: Belongs to the CarB family.

638303:THAL RS07685
gene id: 638303:THAL_RS07685
uniprot id: D3SN11
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03255
gene id: 638303:THAL_RS03255
uniprot id: D3SQ42
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

638303:THAL RS03635
gene id: 638303:THAL_RS03635
uniprot id: D3SQB8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

638303:THAL RS04090
gene id: 638303:THAL_RS04090
uniprot id: D3SL11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

638303:THAL RS05070
gene id: 638303:THAL_RS05070
uniprot id: D3SLJ8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

638303:THAL RS02850
gene id: 638303:THAL_RS02850
uniprot id: D3SPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

638303:THAL RS01570
gene id: 638303:THAL_RS01570
uniprot id: D3SP65
names: Similarity
messages: Belongs to the FUN14 family.

638303:THAL RS04115
gene id: 638303:THAL_RS04115
uniprot id: D3SL16
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

638303:THAL RS07320
gene id: 638303:THAL_RS07320
uniprot id: D3SMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

638303:THAL RS02605
gene id: 638303:THAL_RS02605
uniprot id: D3SPS0
names: Subcellular Location Annotation
messages: Membrane

638303:THAL RS03375
gene id: 638303:THAL_RS03375
uniprot id: D3SQ67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

638303:THAL RS07660
gene id: 638303:THAL_RS07660
uniprot id: D3SN06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

638303:THAL RS03815
gene id: 638303:THAL_RS03815
uniprot id: D3SQF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

638303:THAL RS05315
gene id: 638303:THAL_RS05315
uniprot id: D3SLP5
names: Similarity
messages: Belongs to the HupF/HypC family.

638303:THAL RS07775
gene id: 638303:THAL_RS07775
uniprot id: D3SN28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

638303:THAL RS07555
gene id: 638303:THAL_RS07555
uniprot id: D3SMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

638303:THAL RS00860
gene id: 638303:THAL_RS00860
uniprot id: D3SNS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

638303:THAL RS06265
gene id: 638303:THAL_RS06265
uniprot id: D3SM82
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

638303:THAL RS07810
gene id: 638303:THAL_RS07810
uniprot id: D3SN35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

638303:THAL RS03440
gene id: 638303:THAL_RS03440
uniprot id: D3SQ79
names: Similarity
messages: Belongs to the class-I fumarase family.

638303:THAL RS04545
gene id: 638303:THAL_RS04545
uniprot id: D3SL97
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

638303:THAL RS06235
gene id: 638303:THAL_RS06235
uniprot id: D3SM76
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

638303:THAL RS05660
gene id: 638303:THAL_RS05660
uniprot id: D3SLW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

638303:THAL RS07805
gene id: 638303:THAL_RS07805
uniprot id: D3SN34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

638303:THAL RS02160
gene id: 638303:THAL_RS02160
uniprot id: D3SPI2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

638303:THAL RS07165
gene id: 638303:THAL_RS07165
uniprot id: D3SMQ8
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

638303:THAL RS00890
gene id: 638303:THAL_RS00890
uniprot id: D3SNS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

638303:THAL RS07470
gene id: 638303:THAL_RS07470
uniprot id: D3SMX0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

638303:THAL RS04260
gene id: 638303:THAL_RS04260
uniprot id: D3SL44
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

638303:THAL RS00455
gene id: 638303:THAL_RS00455
uniprot id: D3SNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

638303:THAL RS03940
gene id: 638303:THAL_RS03940
uniprot id: D3SQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

638303:THAL RS05730
gene id: 638303:THAL_RS05730
uniprot id: D3SLX9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

638303:THAL RS04565
gene id: 638303:THAL_RS04565
uniprot id: D3SLA1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

638303:THAL RS02775
gene id: 638303:THAL_RS02775
uniprot id: D3SPV3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

638303:THAL RS03295
gene id: 638303:THAL_RS03295
uniprot id: D3SQ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

638303:THAL RS01100
gene id: 638303:THAL_RS01100
uniprot id: D3SNX1
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.

638303:THAL RS04125
gene id: 638303:THAL_RS04125
uniprot id: D3SL18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

638303:THAL RS00910
gene id: 638303:THAL_RS00910
uniprot id: D3SNT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

638303:THAL RS04690
gene id: 638303:THAL_RS04690
uniprot id: D3SLC2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

638303:THAL RS00785
gene id: 638303:THAL_RS00785
uniprot id: D3SNQ8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

638303:THAL RS06790
gene id: 638303:THAL_RS06790
uniprot id: D3SMI6
names: Similarity
messages: Belongs to the UbiD family.

638303:THAL RS04065
gene id: 638303:THAL_RS04065
uniprot id: D3SL06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

638303:THAL RS03745
gene id: 638303:THAL_RS03745
uniprot id: D3SQD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

638303:THAL RS08120
gene id: 638303:THAL_RS08120
uniprot id: D3SN98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

638303:THAL RS07630
gene id: 638303:THAL_RS07630
uniprot id: D3SN00
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

638303:THAL RS05215
gene id: 638303:THAL_RS05215
uniprot id: D3SLM5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

638303:THAL RS04195
gene id: 638303:THAL_RS04195
uniprot id: D3SL32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

638303:THAL RS03035
gene id: 638303:THAL_RS03035
uniprot id: D3SQ04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.