634498:MRU RS09610
gene id: 634498:MRU_RS09610
uniprot id: D3E046
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrB family.
messages: Cell membrane
messages: Membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

634498:MRU RS08400
gene id: 634498:MRU_RS08400
uniprot id: D3DYY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

634498:MRU RS03035
gene id: 634498:MRU_RS03035
uniprot id: D3E1N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

634498:MRU RS01690
gene id: 634498:MRU_RS01690
uniprot id: D3E005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

634498:MRU RS08935
gene id: 634498:MRU_RS08935
uniprot id: D3DZG1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS02455
gene id: 634498:MRU_RS02455
uniprot id: D3E151
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

634498:MRU RS02450
gene id: 634498:MRU_RS02450
uniprot id: D3E150
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

634498:MRU RS00460
gene id: 634498:MRU_RS00460
uniprot id: D3DYM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

634498:MRU RS09130
gene id: 634498:MRU_RS09130
uniprot id: D3DZJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

634498:MRU RS06710
gene id: 634498:MRU_RS06710
uniprot id: D3E3T0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

634498:MRU RS04675
gene id: 634498:MRU_RS04675
uniprot id: D3E2L7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

634498:MRU RS04175
gene id: 634498:MRU_RS04175
uniprot id: D3E2B7
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS00635
gene id: 634498:MRU_RS00635
uniprot id: D3DYQ7
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

634498:MRU RS01980
gene id: 634498:MRU_RS01980
uniprot id: D3E0J4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

634498:MRU RS05490
gene id: 634498:MRU_RS05490
uniprot id: D3E331
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

634498:MRU RS04965
gene id: 634498:MRU_RS04965
uniprot id: D3E2S6
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS08425
gene id: 634498:MRU_RS08425
uniprot id: D3DYY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

634498:MRU RS08440
gene id: 634498:MRU_RS08440
uniprot id: D3DYY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

634498:MRU RS08475
gene id: 634498:MRU_RS08475
uniprot id: D3DYZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

634498:MRU RS04820
gene id: 634498:MRU_RS04820
uniprot id: D3E2P6
names: Similarity
messages: Belongs to the UPF0179 family.

634498:MRU RS00640
gene id: 634498:MRU_RS00640
uniprot id: D3DYQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

634498:MRU RS04655
gene id: 634498:MRU_RS04655
uniprot id: D3E2L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS09615
gene id: 634498:MRU_RS09615
uniprot id: D3E047
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrC family.
messages: Cell membrane
messages: Membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

634498:MRU RS04645
gene id: 634498:MRU_RS04645
uniprot id: D3E2L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

634498:MRU RS10100
gene id: 634498:MRU_RS10100
uniprot id: D3E0E3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS05100
gene id: 634498:MRU_RS05100
uniprot id: D3E2V4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS02740
gene id: 634498:MRU_RS02740
uniprot id: D3E1A9
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS10305
gene id: 634498:MRU_RS10305
uniprot id: D3E0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

634498:MRU RS04970
gene id: 634498:MRU_RS04970
uniprot id: D3E2S7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

634498:MRU RS10290
gene id: 634498:MRU_RS10290
uniprot id: D3E0S4
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS09595
gene id: 634498:MRU_RS09595
uniprot id: D3E043
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrG family.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

634498:MRU RS08095
gene id: 634498:MRU_RS08095
uniprot id: D3E4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

634498:MRU RS07380
gene id: 634498:MRU_RS07380
uniprot id: D3E465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

634498:MRU RS02690
gene id: 634498:MRU_RS02690
uniprot id: D3E199
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

634498:MRU RS06360
gene id: 634498:MRU_RS06360
uniprot id: D3E3L0
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS05525
gene id: 634498:MRU_RS05525
uniprot id: D3E339
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS00645
gene id: 634498:MRU_RS00645
uniprot id: D3DYQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

634498:MRU RS06735
gene id: 634498:MRU_RS06735
uniprot id: D3E3T5
names: Similarity
messages: Belongs to the UPF0440 family.

634498:MRU RS10545
gene id: 634498:MRU_RS10545
uniprot id: D3E0X4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS03415
gene id: 634498:MRU_RS03415
uniprot id: D3E1W2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

634498:MRU RS00075
gene id: 634498:MRU_RS00075
uniprot id: D3E4H1
names: Similarity
messages: Belongs to the peptidase C1 family.

634498:MRU RS02470
gene id: 634498:MRU_RS02470
uniprot id: D3E154
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

634498:MRU RS02020
gene id: 634498:MRU_RS02020
uniprot id: D3E0K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS11120
gene id: 634498:MRU_RS11120
uniprot id: D3E1I0
names: Similarity
messages: Belongs to the UPF0147 family.

634498:MRU RS04835
gene id: 634498:MRU_RS04835
uniprot id: D3E2P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

634498:MRU RS10605
gene id: 634498:MRU_RS10605
uniprot id: D3E0Y5
names: Similarity
messages: Belongs to the UPF0285 family.

634498:MRU RS08360
gene id: 634498:MRU_RS08360
uniprot id: D3DYX2
names: Similarity
messages: Belongs to the aspartokinase family.

634498:MRU RS08600
gene id: 634498:MRU_RS08600
uniprot id: D3DZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

634498:MRU RS03315
gene id: 634498:MRU_RS03315
uniprot id: D3E1U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

634498:MRU RS07610
gene id: 634498:MRU_RS07610
uniprot id: D3E4B1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS07085
gene id: 634498:MRU_RS07085
uniprot id: D3E407
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

634498:MRU RS02380
gene id: 634498:MRU_RS02380
uniprot id: D3E137
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

634498:MRU RS06740
gene id: 634498:MRU_RS06740
uniprot id: D3E3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

634498:MRU RS02075
gene id: 634498:MRU_RS02075
uniprot id: D3E0L3
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS08350
gene id: 634498:MRU_RS08350
uniprot id: D3DYX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

634498:MRU RS09770
gene id: 634498:MRU_RS09770
uniprot id: D3E078
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS09620
gene id: 634498:MRU_RS09620
uniprot id: D3E048
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

634498:MRU RS04360
gene id: 634498:MRU_RS04360
uniprot id: D3E2F4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

634498:MRU RS02280
gene id: 634498:MRU_RS02280
uniprot id: D3E0Q4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

634498:MRU RS00775
gene id: 634498:MRU_RS00775
uniprot id: D3DYT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS00890
gene id: 634498:MRU_RS00890
uniprot id: D3DYV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

634498:MRU RS07550
gene id: 634498:MRU_RS07550
uniprot id: D3E499
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS08730
gene id: 634498:MRU_RS08730
uniprot id: D3DZ46
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

634498:MRU RS10140
gene id: 634498:MRU_RS10140
uniprot id: D3E0F1
names: Function
messages: Part of a potassium transport system.

634498:MRU RS03435
gene id: 634498:MRU_RS03435
uniprot id: D3E1W6
names: Similarity
messages: Belongs to the tRNA(His) guanylyltransferase family.

634498:MRU RS09755
gene id: 634498:MRU_RS09755
uniprot id: D3E075
names: Similarity
messages: Belongs to the ComB family.

634498:MRU RS02670
gene id: 634498:MRU_RS02670
uniprot id: D3E194
names: Function
names: Similarity
messages: Belongs to the HMD family.
messages: Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.

634498:MRU RS10220
gene id: 634498:MRU_RS10220
uniprot id: D3E0G0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

634498:MRU RS08235
gene id: 634498:MRU_RS08235
uniprot id: D3E4V1
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

634498:MRU RS04230
gene id: 634498:MRU_RS04230
uniprot id: D3E2C7
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

634498:MRU RS07105
gene id: 634498:MRU_RS07105
uniprot id: D3E411
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

634498:MRU RS06340
gene id: 634498:MRU_RS06340
uniprot id: D3E3K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

634498:MRU RS03325
gene id: 634498:MRU_RS03325
uniprot id: D3E1U4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

634498:MRU RS03925
gene id: 634498:MRU_RS03925
uniprot id: D3E266
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

634498:MRU RS07065
gene id: 634498:MRU_RS07065
uniprot id: D3E403
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
messages: Homodimer.

634498:MRU RS07790
gene id: 634498:MRU_RS07790
uniprot id: D3E4E9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

634498:MRU RS12055
gene id: 634498:MRU_RS12055
uniprot id: D3E2A6
names: Similarity
messages: Belongs to the HdrC family.

634498:MRU RS03405
gene id: 634498:MRU_RS03405
uniprot id: D3E1W0
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS10410
gene id: 634498:MRU_RS10410
uniprot id: D3E0U5
names: Similarity
messages: Belongs to the UPF0305 family.

634498:MRU RS09550
gene id: 634498:MRU_RS09550
uniprot id: D3E034
names: Similarity
messages: Belongs to the MvhD/VhuD family.

634498:MRU RS05385
gene id: 634498:MRU_RS05385
uniprot id: D3E310
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS04415
gene id: 634498:MRU_RS04415
uniprot id: D3E2G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

634498:MRU RS09445
gene id: 634498:MRU_RS09445
uniprot id: D3DZQ9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

634498:MRU RS02530
gene id: 634498:MRU_RS02530
uniprot id: D3E166
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

634498:MRU RS09330
gene id: 634498:MRU_RS09330
uniprot id: D3DZN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

634498:MRU RS00450
gene id: 634498:MRU_RS00450
uniprot id: D3DYL9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'-methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'-deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'-deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'-deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: SAH is a product of SAM methyltransferases and is known to be a feedback inhibitor of these enzymes. As a result of this inhibition, organisms have evolved efficient enzymes to metabolize SAH via different pathways. The pathway found in methanogens differs from the canonical pathway, it uses the deamination of S-adenosyl-L-homocysteine to form S-inosyl-L-homocysteine for the regeneration of SAM from S-adenosyl-L-homocysteine. 5'-deoxyadenosine is a radical SAM enzyme reaction product which strongly inhibits radical SAM enzymes. A pathway for removing this product must be present in methanogens where the MTA/SAH nucleosidase which normally metabolizes this compound is absent.

634498:MRU RS09640
gene id: 634498:MRU_RS09640
uniprot id: D3E052
names: Subunit
messages: MCR is composed of three subunits: alpha, beta, and gamma. The function of proteins C and D is not known.

634498:MRU RS02325
gene id: 634498:MRU_RS02325
uniprot id: D3E127
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

634498:MRU RS04320
gene id: 634498:MRU_RS04320
uniprot id: D3E2E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

634498:MRU RS02025
gene id: 634498:MRU_RS02025
uniprot id: D3E0K3
names: Similarity
messages: Belongs to the PDCD5 family.

634498:MRU RS03490
gene id: 634498:MRU_RS03490
uniprot id: D3E1X8
names: Similarity
messages: Belongs to the PrpD family.

634498:MRU RS10990
gene id: 634498:MRU_RS10990
uniprot id: D3E1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

634498:MRU RS06365
gene id: 634498:MRU_RS06365
uniprot id: D3E3L1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS02335
gene id: 634498:MRU_RS02335
uniprot id: D3E129
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

634498:MRU RS03565
gene id: 634498:MRU_RS03565
uniprot id: D3E1Z3
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

634498:MRU RS09820
gene id: 634498:MRU_RS09820
uniprot id: D3E088
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

634498:MRU RS08390
gene id: 634498:MRU_RS08390
uniprot id: D3DYX8
names: Similarity
messages: Belongs to the glutaredoxin family.

634498:MRU RS07440
gene id: 634498:MRU_RS07440
uniprot id: D3E477
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

634498:MRU RS05975
gene id: 634498:MRU_RS05975
uniprot id: D3E3D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

634498:MRU RS10085
gene id: 634498:MRU_RS10085
uniprot id: D3E0E0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

634498:MRU RS04530
gene id: 634498:MRU_RS04530
uniprot id: D3E2I8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

634498:MRU RS08740
gene id: 634498:MRU_RS08740
uniprot id: D3DZ48
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

634498:MRU RS02410
gene id: 634498:MRU_RS02410
uniprot id: D3E143
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

634498:MRU RS04365
gene id: 634498:MRU_RS04365
uniprot id: D3E2F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

634498:MRU RS01075
gene id: 634498:MRU_RS01075
uniprot id: D3DZB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

634498:MRU RS10365
gene id: 634498:MRU_RS10365
uniprot id: D3E0T8
names: Similarity
messages: Belongs to the FrhG family.

634498:MRU RS04745
gene id: 634498:MRU_RS04745
uniprot id: D3E2N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

634498:MRU RS02700
gene id: 634498:MRU_RS02700
uniprot id: D3E1A1
names: Similarity
messages: Belongs to the UPF0254 family.

634498:MRU RS01230
gene id: 634498:MRU_RS01230
uniprot id: D3DZC6
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

634498:MRU RS04340
gene id: 634498:MRU_RS04340
uniprot id: D3E2F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

634498:MRU RS02010
gene id: 634498:MRU_RS02010
uniprot id: D3E0K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

634498:MRU RS04355
gene id: 634498:MRU_RS04355
uniprot id: D3E2F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

634498:MRU RS02085
gene id: 634498:MRU_RS02085
uniprot id: D3E0L5
names: Similarity
messages: Belongs to the TPP enzyme family.

634498:MRU RS07275
gene id: 634498:MRU_RS07275
uniprot id: D3E445
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS01060
gene id: 634498:MRU_RS01060
uniprot id: D3DZA8
names: Similarity
messages: Belongs to the TrpC family.

634498:MRU RS09950
gene id: 634498:MRU_RS09950
uniprot id: D3E0B3
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

634498:MRU RS00005
gene id: 634498:MRU_RS00005
uniprot id: D3E4F7
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

634498:MRU RS07880
gene id: 634498:MRU_RS07880
uniprot id: D3E4M9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

634498:MRU RS04460
gene id: 634498:MRU_RS04460
uniprot id: D3E2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

634498:MRU RS03915
gene id: 634498:MRU_RS03915
uniprot id: D3E264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

634498:MRU RS02230
gene id: 634498:MRU_RS02230
uniprot id: D3E0P4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS10265
gene id: 634498:MRU_RS10265
uniprot id: D3E0R9
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS04335
gene id: 634498:MRU_RS04335
uniprot id: D3E2E9
names: Similarity
messages: Belongs to the SUI1 family.

634498:MRU RS06350
gene id: 634498:MRU_RS06350
uniprot id: D3E3K8
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS00410
gene id: 634498:MRU_RS00410
uniprot id: D3DYL1
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS04450
gene id: 634498:MRU_RS04450
uniprot id: D3E2H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

634498:MRU RS10595
gene id: 634498:MRU_RS10595
uniprot id: D3E0Y3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

634498:MRU RS06525
gene id: 634498:MRU_RS06525
uniprot id: D3E3P4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

634498:MRU RS00770
gene id: 634498:MRU_RS00770
uniprot id: D3DYT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

634498:MRU RS00810
gene id: 634498:MRU_RS00810
uniprot id: D3DYU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

634498:MRU RS09235
gene id: 634498:MRU_RS09235
uniprot id: D3DZL7
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

634498:MRU RS05760
gene id: 634498:MRU_RS05760
uniprot id: D3E387
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

634498:MRU RS01070
gene id: 634498:MRU_RS01070
uniprot id: D3DZB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

634498:MRU RS02830
gene id: 634498:MRU_RS02830
uniprot id: D3E1J6
names: Similarity
messages: Belongs to the class-I fumarase family.

634498:MRU RS07095
gene id: 634498:MRU_RS07095
uniprot id: D3E409
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

634498:MRU RS11115
gene id: 634498:MRU_RS11115
uniprot id: D3E1H9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

634498:MRU RS05070
gene id: 634498:MRU_RS05070
uniprot id: D3E2U7
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

634498:MRU RS08805
gene id: 634498:MRU_RS08805
uniprot id: D3DZ61
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

634498:MRU RS04310
gene id: 634498:MRU_RS04310
uniprot id: D3E2E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

634498:MRU RS09530
gene id: 634498:MRU_RS09530
uniprot id: D3DZS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

634498:MRU RS07390
gene id: 634498:MRU_RS07390
uniprot id: D3E467
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

634498:MRU RS02555
gene id: 634498:MRU_RS02555
uniprot id: D3E171
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane

634498:MRU RS10750
gene id: 634498:MRU_RS10750
uniprot id: D3E113
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

634498:MRU RS01885
gene id: 634498:MRU_RS01885
uniprot id: D3E0G4
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS06190
gene id: 634498:MRU_RS06190
uniprot id: D3E3H6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS08775
gene id: 634498:MRU_RS08775
uniprot id: D3DZ55
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

634498:MRU RS04660
gene id: 634498:MRU_RS04660
uniprot id: D3E2L4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

634498:MRU RS00870
gene id: 634498:MRU_RS00870
uniprot id: D3DYV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

634498:MRU RS01795
gene id: 634498:MRU_RS01795
uniprot id: D3E026
names: Similarity
messages: Belongs to the glutamine synthetase family.

634498:MRU RS02720
gene id: 634498:MRU_RS02720
uniprot id: D3E1A5
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS02240
gene id: 634498:MRU_RS02240
uniprot id: D3E0P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrA family.
messages: Binds 1 5-hydroxybenzimidazolylcobamide group.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

634498:MRU RS07750
gene id: 634498:MRU_RS07750
uniprot id: D3E4E1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS05660
gene id: 634498:MRU_RS05660
uniprot id: D3E367
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

634498:MRU RS01955
gene id: 634498:MRU_RS01955
uniprot id: D3E0J0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

634498:MRU RS11105
gene id: 634498:MRU_RS11105
uniprot id: D3E1H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

634498:MRU RS00815
gene id: 634498:MRU_RS00815
uniprot id: D3DYU4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

634498:MRU RS00555
gene id: 634498:MRU_RS00555
uniprot id: D3DYP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

634498:MRU RS10745
gene id: 634498:MRU_RS10745
uniprot id: D3E112
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS03350
gene id: 634498:MRU_RS03350
uniprot id: D3E1U9
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS03610
gene id: 634498:MRU_RS03610
uniprot id: D3E201
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

634498:MRU RS10485
gene id: 634498:MRU_RS10485
uniprot id: D3E0W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS05410
gene id: 634498:MRU_RS05410
uniprot id: D3E315
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

634498:MRU RS03410
gene id: 634498:MRU_RS03410
uniprot id: D3E1W1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS03160
gene id: 634498:MRU_RS03160
uniprot id: D3E1Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

634498:MRU RS00355
gene id: 634498:MRU_RS00355
uniprot id: D3DYK1
names: Subcellular Location Annotation
messages: Cell membrane

634498:MRU RS03150
gene id: 634498:MRU_RS03150
uniprot id: D3E1Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

634498:MRU RS10670
gene id: 634498:MRU_RS10670
uniprot id: D3E0Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

634498:MRU RS10660
gene id: 634498:MRU_RS10660
uniprot id: D3E0Z5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS05480
gene id: 634498:MRU_RS05480
uniprot id: D3E329
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS10650
gene id: 634498:MRU_RS10650
uniprot id: D3E0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

634498:MRU RS05550
gene id: 634498:MRU_RS05550
uniprot id: D3E345
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

634498:MRU RS05030
gene id: 634498:MRU_RS05030
uniprot id: D3E2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

634498:MRU RS10515
gene id: 634498:MRU_RS10515
uniprot id: D3E0W8
names: Subcellular Location Annotation
messages: Cytoplasm

634498:MRU RS09515
gene id: 634498:MRU_RS09515
uniprot id: D3DZS3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

634498:MRU RS00950
gene id: 634498:MRU_RS00950
uniprot id: D3DZ86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS01040
gene id: 634498:MRU_RS01040
uniprot id: D3DZA4
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS05235
gene id: 634498:MRU_RS05235
uniprot id: D3E2Y1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS10475
gene id: 634498:MRU_RS10475
uniprot id: D3E0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS04880
gene id: 634498:MRU_RS04880
uniprot id: D3E2Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

634498:MRU RS08255
gene id: 634498:MRU_RS08255
uniprot id: D3E4V6
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS04145
gene id: 634498:MRU_RS04145
uniprot id: D3E2B2
names: Function
names: Similarity
messages: Belongs to the 2-phosphoglycerate kinase family.
messages: Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate. Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant.

634498:MRU RS10560
gene id: 634498:MRU_RS10560
uniprot id: D3E0X7
names: Similarity
messages: Belongs to the UPF0284 family.

634498:MRU RS04255
gene id: 634498:MRU_RS04255
uniprot id: D3E2D2
names: Similarity
messages: Belongs to the peptidase C1 family.

634498:MRU RS03045
gene id: 634498:MRU_RS03045
uniprot id: D3E1N5
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

634498:MRU RS01705
gene id: 634498:MRU_RS01705
uniprot id: D3E008
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

634498:MRU RS07545
gene id: 634498:MRU_RS07545
uniprot id: D3E498
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

634498:MRU RS04400
gene id: 634498:MRU_RS04400
uniprot id: D3E2G2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

634498:MRU RS09135
gene id: 634498:MRU_RS09135
uniprot id: D3DZJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

634498:MRU RS07505
gene id: 634498:MRU_RS07505
uniprot id: D3E490
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

634498:MRU RS06135
gene id: 634498:MRU_RS06135
uniprot id: D3E3G5
names: Similarity
messages: Belongs to the thymidylate kinase family.

634498:MRU RS10490
gene id: 634498:MRU_RS10490
uniprot id: D3E0W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

634498:MRU RS08710
gene id: 634498:MRU_RS08710
uniprot id: D3DZ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

634498:MRU RS05715
gene id: 634498:MRU_RS05715
uniprot id: D3E378
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

634498:MRU RS06380
gene id: 634498:MRU_RS06380
uniprot id: D3E3L4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS02165
gene id: 634498:MRU_RS02165
uniprot id: D3E0N1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

634498:MRU RS04170
gene id: 634498:MRU_RS04170
uniprot id: D3E2B6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

634498:MRU RS01360
gene id: 634498:MRU_RS01360
uniprot id: D3DZT1
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS07280
gene id: 634498:MRU_RS07280
uniprot id: D3E446
names: Similarity
messages: Belongs to the ABC transporter superfamily.

634498:MRU RS07690
gene id: 634498:MRU_RS07690
uniprot id: D3E4C9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

634498:MRU RS03105
gene id: 634498:MRU_RS03105
uniprot id: D3E1P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

634498:MRU RS11265
gene id: 634498:MRU_RS11265
uniprot id: D3E0Y8
names: Similarity
messages: Belongs to the TPP enzyme family.

634498:MRU RS03020
gene id: 634498:MRU_RS03020
uniprot id: D3E1N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

634498:MRU RS00845
gene id: 634498:MRU_RS00845
uniprot id: D3DYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

634498:MRU RS02055
gene id: 634498:MRU_RS02055
uniprot id: D3E0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

634498:MRU RS01760
gene id: 634498:MRU_RS01760
uniprot id: D3E019
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FwdB family.
messages: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile.
messages: This enzyme is composed of six subunits FwdA, FwdC, FwdD, FwdE, FwdF and FwdG.

634498:MRU RS03235
gene id: 634498:MRU_RS03235
uniprot id: D3E1S5
names: Similarity
messages: Belongs to the pyruvate kinase family.

634498:MRU RS04570
gene id: 634498:MRU_RS04570
uniprot id: D3E2J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

634498:MRU RS09745
gene id: 634498:MRU_RS09745
uniprot id: D3E073
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

634498:MRU RS08420
gene id: 634498:MRU_RS08420
uniprot id: D3DYY4
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

634498:MRU RS05670
gene id: 634498:MRU_RS05670
uniprot id: D3E369
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

634498:MRU RS09110
gene id: 634498:MRU_RS09110
uniprot id: D3DZJ1
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

634498:MRU RS09625
gene id: 634498:MRU_RS09625
uniprot id: D3E049
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

634498:MRU RS06620
gene id: 634498:MRU_RS06620
uniprot id: D3E3R3
names: Function
names: Similarity
messages: Belongs to the P(II) protein family.
messages: Could be involved in the regulation of nitrogen fixation.

634498:MRU RS03560
gene id: 634498:MRU_RS03560
uniprot id: D3E1Z2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

634498:MRU RS01990
gene id: 634498:MRU_RS01990
uniprot id: D3E0J6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

634498:MRU RS02255
gene id: 634498:MRU_RS02255
uniprot id: D3E0P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

634498:MRU RS04120
gene id: 634498:MRU_RS04120
uniprot id: D3E2A7
names: Function
names: Similarity
messages: Belongs to the HdrB family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).

634498:MRU RS06370
gene id: 634498:MRU_RS06370
uniprot id: D3E3L2
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS02465
gene id: 634498:MRU_RS02465
uniprot id: D3E153
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

634498:MRU RS05920
gene id: 634498:MRU_RS05920
uniprot id: D3E3C1
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

634498:MRU RS08880
gene id: 634498:MRU_RS08880
uniprot id: D3DZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

634498:MRU RS09475
gene id: 634498:MRU_RS09475
uniprot id: D3DZR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

634498:MRU RS10125
gene id: 634498:MRU_RS10125
uniprot id: D3E0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR).
messages: Cytoplasm
messages: Homotetramer.

634498:MRU RS06105
gene id: 634498:MRU_RS06105
uniprot id: D3E3F9
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

634498:MRU RS03665
gene id: 634498:MRU_RS03665
uniprot id: D3E212
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS09495
gene id: 634498:MRU_RS09495
uniprot id: D3DZR9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

634498:MRU RS04395
gene id: 634498:MRU_RS04395
uniprot id: D3E2G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

634498:MRU RS04465
gene id: 634498:MRU_RS04465
uniprot id: D3E2H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

634498:MRU RS09805
gene id: 634498:MRU_RS09805
uniprot id: D3E085
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

634498:MRU RS05470
gene id: 634498:MRU_RS05470
uniprot id: D3E327
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

634498:MRU RS00620
gene id: 634498:MRU_RS00620
uniprot id: D3DYQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS04410
gene id: 634498:MRU_RS04410
uniprot id: D3E2G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

634498:MRU RS09930
gene id: 634498:MRU_RS09930
uniprot id: D3E0A9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

634498:MRU RS02210
gene id: 634498:MRU_RS02210
uniprot id: D3E0P0
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

634498:MRU RS06550
gene id: 634498:MRU_RS06550
uniprot id: D3E3P9
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

634498:MRU RS06600
gene id: 634498:MRU_RS06600
uniprot id: D3E3Q9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

634498:MRU RS07560
gene id: 634498:MRU_RS07560
uniprot id: D3E4A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

634498:MRU RS07070
gene id: 634498:MRU_RS07070
uniprot id: D3E404
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

634498:MRU RS09070
gene id: 634498:MRU_RS09070
uniprot id: D3DZI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The Rpo2 subunit (Rpo2N and Rpo2C in this organism) is implicated in DNA promoter recognition and in nucleotide binding.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

634498:MRU RS06780
gene id: 634498:MRU_RS06780
uniprot id: D3E3U4
names: Similarity
messages: Belongs to the SDO1/SBDS family.

634498:MRU RS09245
gene id: 634498:MRU_RS09245
uniprot id: D3DZL9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

634498:MRU RS10275
gene id: 634498:MRU_RS10275
uniprot id: D3E0S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

634498:MRU RS02460
gene id: 634498:MRU_RS02460
uniprot id: D3E152
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

634498:MRU RS05015
gene id: 634498:MRU_RS05015
uniprot id: D3E2T6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

634498:MRU RS00550
gene id: 634498:MRU_RS00550
uniprot id: D3DYP0
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

634498:MRU RS01335
gene id: 634498:MRU_RS01335
uniprot id: D3DZE7
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

634498:MRU RS08190
gene id: 634498:MRU_RS08190
uniprot id: D3E4U4
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS04300
gene id: 634498:MRU_RS04300
uniprot id: D3E2E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

634498:MRU RS03000
gene id: 634498:MRU_RS03000
uniprot id: D3E1M6
names: Similarity
messages: Belongs to the thymidylate kinase family.

634498:MRU RS04610
gene id: 634498:MRU_RS04610
uniprot id: D3E2K4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

634498:MRU RS08615
gene id: 634498:MRU_RS08615
uniprot id: D3DZ22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

634498:MRU RS06875
gene id: 634498:MRU_RS06875
uniprot id: D3E3W4
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS01295
gene id: 634498:MRU_RS01295
uniprot id: D3DZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

634498:MRU RS10850
gene id: 634498:MRU_RS10850
uniprot id: D3E1C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

634498:MRU RS02675
gene id: 634498:MRU_RS02675
uniprot id: D3E195
names: Cofactor
names: Similarity
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

634498:MRU RS04020
gene id: 634498:MRU_RS04020
uniprot id: D3E286
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

634498:MRU RS04240
gene id: 634498:MRU_RS04240
uniprot id: D3E2C9
names: Similarity
messages: Belongs to the peptidase C1 family.

634498:MRU RS06225
gene id: 634498:MRU_RS06225
uniprot id: D3E3I3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS10810
gene id: 634498:MRU_RS10810
uniprot id: D3E1B6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP, and cobyrinate or Ni-sirohydrochlorin, and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate and Ni-sirohydrochlorin are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

634498:MRU RS02120
gene id: 634498:MRU_RS02120
uniprot id: D3E0M2
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS04140
gene id: 634498:MRU_RS04140
uniprot id: D3E2B1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS11010
gene id: 634498:MRU_RS11010
uniprot id: D3E1F7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

634498:MRU RS04325
gene id: 634498:MRU_RS04325
uniprot id: D3E2E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS05595
gene id: 634498:MRU_RS05595
uniprot id: D3E354
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

634498:MRU RS04565
gene id: 634498:MRU_RS04565
uniprot id: D3E2J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

634498:MRU RS02895
gene id: 634498:MRU_RS02895
uniprot id: D3E1K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT.
messages: Cytoplasm

634498:MRU RS05885
gene id: 634498:MRU_RS05885
uniprot id: D3E3B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

634498:MRU RS02005
gene id: 634498:MRU_RS02005
uniprot id: D3E0J9
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS10240
gene id: 634498:MRU_RS10240
uniprot id: D3E0R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

634498:MRU RS02170
gene id: 634498:MRU_RS02170
uniprot id: D3E0N2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

634498:MRU RS03670
gene id: 634498:MRU_RS03670
uniprot id: D3E213
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS04595
gene id: 634498:MRU_RS04595
uniprot id: D3E2K1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

634498:MRU RS00575
gene id: 634498:MRU_RS00575
uniprot id: D3DYP5
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS02035
gene id: 634498:MRU_RS02035
uniprot id: D3E0K5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

634498:MRU RS05000
gene id: 634498:MRU_RS05000
uniprot id: D3E2T3
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS03430
gene id: 634498:MRU_RS03430
uniprot id: D3E1W5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

634498:MRU RS02985
gene id: 634498:MRU_RS02985
uniprot id: D3E1M3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

634498:MRU RS07740
gene id: 634498:MRU_RS07740
uniprot id: D3E4D9
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS03155
gene id: 634498:MRU_RS03155
uniprot id: D3E1Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

634498:MRU RS02260
gene id: 634498:MRU_RS02260
uniprot id: D3E0Q0
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS03310
gene id: 634498:MRU_RS03310
uniprot id: D3E1U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

634498:MRU RS10770
gene id: 634498:MRU_RS10770
uniprot id: D3E118
names: Function
names: Similarity
messages: Belongs to the MTD family.
messages: Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.

634498:MRU RS10015
gene id: 634498:MRU_RS10015
uniprot id: D3E0C6
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS08750
gene id: 634498:MRU_RS08750
uniprot id: D3DZ50
names: Similarity
messages: Belongs to the NAPRTase family.

634498:MRU RS04815
gene id: 634498:MRU_RS04815
uniprot id: D3E2P5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homooctamer.

634498:MRU RS00585
gene id: 634498:MRU_RS00585
uniprot id: D3DYP7
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

634498:MRU RS09955
gene id: 634498:MRU_RS09955
uniprot id: D3E0B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

634498:MRU RS06765
gene id: 634498:MRU_RS06765
uniprot id: D3E3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

634498:MRU RS07395
gene id: 634498:MRU_RS07395
uniprot id: D3E468
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

634498:MRU RS08660
gene id: 634498:MRU_RS08660
uniprot id: D3DZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

634498:MRU RS09280
gene id: 634498:MRU_RS09280
uniprot id: D3DZM6
names: Similarity
messages: Belongs to the AAA ATPase family.

634498:MRU RS10440
gene id: 634498:MRU_RS10440
uniprot id: D3E0V3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS06660
gene id: 634498:MRU_RS06660
uniprot id: D3E3S1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS08720
gene id: 634498:MRU_RS08720
uniprot id: D3DZ44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS10715
gene id: 634498:MRU_RS10715
uniprot id: D3E106
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS00345
gene id: 634498:MRU_RS00345
uniprot id: D3E4M3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

634498:MRU RS06555
gene id: 634498:MRU_RS06555
uniprot id: D3E3Q0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

634498:MRU RS07795
gene id: 634498:MRU_RS07795
uniprot id: D3E4F0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

634498:MRU RS06245
gene id: 634498:MRU_RS06245
uniprot id: D3E3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

634498:MRU RS00540
gene id: 634498:MRU_RS00540
uniprot id: D3DYN8
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homotetramer; probably dimer of dimers.

634498:MRU RS07960
gene id: 634498:MRU_RS07960
uniprot id: D3E4P5
names: Similarity
messages: Belongs to the UPF0047 family.

634498:MRU RS07780
gene id: 634498:MRU_RS07780
uniprot id: D3E4E7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

634498:MRU RS09205
gene id: 634498:MRU_RS09205
uniprot id: D3DZL1
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

634498:MRU RS09075
gene id: 634498:MRU_RS09075
uniprot id: D3DZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The Rpo2 subunit (Rpo2N and Rpo2C in this organism) is implicated in DNA promoter recognition and in nucleotide binding.
messages: Part of the RNA polymerase complex.

634498:MRU RS09685
gene id: 634498:MRU_RS09685
uniprot id: D3E061
names: Similarity
messages: Belongs to the glutathione peroxidase family.

634498:MRU RS00920
gene id: 634498:MRU_RS00920
uniprot id: D3DZ80
names: Similarity
messages: Belongs to the glutaredoxin family.

634498:MRU RS01095
gene id: 634498:MRU_RS01095
uniprot id: D3DZB5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.

634498:MRU RS09775
gene id: 634498:MRU_RS09775
uniprot id: D3E079
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS03100
gene id: 634498:MRU_RS03100
uniprot id: D3E1P6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

634498:MRU RS09290
gene id: 634498:MRU_RS09290
uniprot id: D3DZM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

634498:MRU RS06500
gene id: 634498:MRU_RS06500
uniprot id: D3E3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

634498:MRU RS07055
gene id: 634498:MRU_RS07055
uniprot id: D3E401
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EhaA family.
messages: Cell membrane
messages: Membrane
messages: One of the integral membrane subunits of multisubunit membrane-bound [NiFe]-hydrogenase eha. Eha is predicted to form large electron transfer complex and might catalyze energy-driven reduction of low-potential redox carriers.
messages: Putative multisubunit membrane-bound [NiFe]-hydrogenase eha is composed of at least 20 subunits.

634498:MRU RS01835
gene id: 634498:MRU_RS01835
uniprot id: D3E0G4
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS07670
gene id: 634498:MRU_RS07670
uniprot id: D3E4C5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS08715
gene id: 634498:MRU_RS08715
uniprot id: D3DZ43
names: Similarity
messages: Belongs to the PdaD family.

634498:MRU RS04825
gene id: 634498:MRU_RS04825
uniprot id: D3E2P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

634498:MRU RS04650
gene id: 634498:MRU_RS04650
uniprot id: D3E2L2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS10710
gene id: 634498:MRU_RS10710
uniprot id: D3E105
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS09470
gene id: 634498:MRU_RS09470
uniprot id: D3DZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

634498:MRU RS06690
gene id: 634498:MRU_RS06690
uniprot id: D3E3S6
names: Similarity
messages: Belongs to the HisA/HisF family.

634498:MRU RS06250
gene id: 634498:MRU_RS06250
uniprot id: D3E3I8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS00500
gene id: 634498:MRU_RS00500
uniprot id: D3DYN0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

634498:MRU RS04030
gene id: 634498:MRU_RS04030
uniprot id: D3E288
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

634498:MRU RS03555
gene id: 634498:MRU_RS03555
uniprot id: D3E1Z1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

634498:MRU RS03595
gene id: 634498:MRU_RS03595
uniprot id: D3E1Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

634498:MRU RS00365
gene id: 634498:MRU_RS00365
uniprot id: D3DYK3
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS12210
gene id: 634498:MRU_RS12210
uniprot id: D3E0S8
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS12060
gene id: 634498:MRU_RS12060
uniprot id: D3E2R8
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS00595
gene id: 634498:MRU_RS00595
uniprot id: D3DYP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

634498:MRU RS00440
gene id: 634498:MRU_RS00440
uniprot id: D3DYL7
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS03025
gene id: 634498:MRU_RS03025
uniprot id: D3E1N1
names: Similarity
messages: Belongs to the MCM family.

634498:MRU RS09025
gene id: 634498:MRU_RS09025
uniprot id: D3DZH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS03550
gene id: 634498:MRU_RS03550
uniprot id: D3E1Z0
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

634498:MRU RS04500
gene id: 634498:MRU_RS04500
uniprot id: D3E2I2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
messages: Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.

634498:MRU RS01475
gene id: 634498:MRU_RS01475
uniprot id: D3DZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

634498:MRU RS09630
gene id: 634498:MRU_RS09630
uniprot id: D3E050
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase alpha subunit family.
messages: Binds 2 coenzyme F430 non-covalently per MCR complex. Coenzyme F430 is a yellow nickel porphinoid. Methyl-coenzyme-M reductase is activated when the enzyme-bound coenzyme F430 is reduced to the Ni(I) oxidation state.
messages: Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

634498:MRU RS10555
gene id: 634498:MRU_RS10555
uniprot id: D3E0X6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

634498:MRU RS08250
gene id: 634498:MRU_RS08250
uniprot id: D3E4V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

634498:MRU RS08140
gene id: 634498:MRU_RS08140
uniprot id: D3E4T4
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS01970
gene id: 634498:MRU_RS01970
uniprot id: D3E0J3
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

634498:MRU RS04810
gene id: 634498:MRU_RS04810
uniprot id: D3E2P4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS05445
gene id: 634498:MRU_RS05445
uniprot id: D3E322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

634498:MRU RS05295
gene id: 634498:MRU_RS05295
uniprot id: D3E2Z3
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

634498:MRU RS04790
gene id: 634498:MRU_RS04790
uniprot id: D3E2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

634498:MRU RS04730
gene id: 634498:MRU_RS04730
uniprot id: D3E2M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

634498:MRU RS05915
gene id: 634498:MRU_RS05915
uniprot id: D3E3C0
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

634498:MRU RS09165
gene id: 634498:MRU_RS09165
uniprot id: D3DZK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

634498:MRU RS02475
gene id: 634498:MRU_RS02475
uniprot id: D3E155
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

634498:MRU RS08995
gene id: 634498:MRU_RS08995
uniprot id: D3DZH3
names: Similarity
messages: Belongs to the UPF0146 family.

634498:MRU RS02400
gene id: 634498:MRU_RS02400
uniprot id: D3E141
names: Similarity
messages: Belongs to the HupF/HypC family.

634498:MRU RS09900
gene id: 634498:MRU_RS09900
uniprot id: D3E0A3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

634498:MRU RS09255
gene id: 634498:MRU_RS09255
uniprot id: D3DZM1
names: Similarity
messages: Belongs to the UPF0251 family.

634498:MRU RS07445
gene id: 634498:MRU_RS07445
uniprot id: D3E478
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

634498:MRU RS03450
gene id: 634498:MRU_RS03450
uniprot id: D3E1W9
names: Similarity
messages: Belongs to the UPF0145 family.

634498:MRU RS03590
gene id: 634498:MRU_RS03590
uniprot id: D3E1Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

634498:MRU RS11155
gene id: 634498:MRU_RS11155
uniprot id: D3E4J5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

634498:MRU RS04620
gene id: 634498:MRU_RS04620
uniprot id: D3E2K6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

634498:MRU RS06335
gene id: 634498:MRU_RS06335
uniprot id: D3E3K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

634498:MRU RS04425
gene id: 634498:MRU_RS04425
uniprot id: D3E2G7
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS08170
gene id: 634498:MRU_RS08170
uniprot id: D3E4U0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS08345
gene id: 634498:MRU_RS08345
uniprot id: D3DYW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS06795
gene id: 634498:MRU_RS06795
uniprot id: D3E3U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

634498:MRU RS10110
gene id: 634498:MRU_RS10110
uniprot id: D3E0E5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS04430
gene id: 634498:MRU_RS04430
uniprot id: D3E2G8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

634498:MRU RS06415
gene id: 634498:MRU_RS06415
uniprot id: D3E3M2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the creatininase superfamily. FAPy deformylase family.
messages: Catalyzes the hydrolysis of the formamide of 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
messages: Homodimer.
messages: Requires an additional second metal ion that could be Fe(2+) or Zn(2+).
messages: Requires one Fe(2+) ion for activity.

634498:MRU RS06585
gene id: 634498:MRU_RS06585
uniprot id: D3E3Q6
names: Similarity
messages: Belongs to the IMPACT family.

634498:MRU RS02315
gene id: 634498:MRU_RS02315
uniprot id: D3E124
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

634498:MRU RS03295
gene id: 634498:MRU_RS03295
uniprot id: D3E1T8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

634498:MRU RS06050
gene id: 634498:MRU_RS06050
uniprot id: D3E3E8
names: Function
names: Similarity
messages: Belongs to the MfnB family.
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

634498:MRU RS07775
gene id: 634498:MRU_RS07775
uniprot id: D3E4E6
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

634498:MRU RS09410
gene id: 634498:MRU_RS09410
uniprot id: D3DZQ2
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS09650
gene id: 634498:MRU_RS09650
uniprot id: D3E054
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase beta subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

634498:MRU RS02225
gene id: 634498:MRU_RS02225
uniprot id: D3E0P3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

634498:MRU RS07405
gene id: 634498:MRU_RS07405
uniprot id: D3E470
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

634498:MRU RS07760
gene id: 634498:MRU_RS07760
uniprot id: D3E4E3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.

634498:MRU RS03110
gene id: 634498:MRU_RS03110
uniprot id: D3E1P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

634498:MRU RS05535
gene id: 634498:MRU_RS05535
uniprot id: D3E342
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

634498:MRU RS04600
gene id: 634498:MRU_RS04600
uniprot id: D3E2K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

634498:MRU RS09485
gene id: 634498:MRU_RS09485
uniprot id: D3DZR7
names: Similarity
messages: Belongs to the class-I fumarase family.

634498:MRU RS01065
gene id: 634498:MRU_RS01065
uniprot id: D3DZA9
names: Similarity
messages: Belongs to the TrpF family.

634498:MRU RS06390
gene id: 634498:MRU_RS06390
uniprot id: D3E3L6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

634498:MRU RS06030
gene id: 634498:MRU_RS06030
uniprot id: D3E3E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

634498:MRU RS02140
gene id: 634498:MRU_RS02140
uniprot id: D3E0M6
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

634498:MRU RS10195
gene id: 634498:MRU_RS10195
uniprot id: D3E0F5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

634498:MRU RS09335
gene id: 634498:MRU_RS09335
uniprot id: D3DZN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

634498:MRU RS02040
gene id: 634498:MRU_RS02040
uniprot id: D3E0K6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

634498:MRU RS06770
gene id: 634498:MRU_RS06770
uniprot id: D3E3U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

634498:MRU RS09600
gene id: 634498:MRU_RS09600
uniprot id: D3E044
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrF family.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

634498:MRU RS00895
gene id: 634498:MRU_RS00895
uniprot id: D3DYW0
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

634498:MRU RS09460
gene id: 634498:MRU_RS09460
uniprot id: D3DZR2
names: Similarity
messages: Belongs to the LarC family.

634498:MRU RS03065
gene id: 634498:MRU_RS03065
uniprot id: D3E1N9
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS10610
gene id: 634498:MRU_RS10610
uniprot id: D3E0Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS11110
gene id: 634498:MRU_RS11110
uniprot id: D3E1H8
names: Subunit
messages: Homotetramer.

634498:MRU RS08165
gene id: 634498:MRU_RS08165
uniprot id: D3E4T9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

634498:MRU RS04000
gene id: 634498:MRU_RS04000
uniprot id: D3E282
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

634498:MRU RS00755
gene id: 634498:MRU_RS00755
uniprot id: D3DYT1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

634498:MRU RS07220
gene id: 634498:MRU_RS07220
uniprot id: D3E434
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

634498:MRU RS01700
gene id: 634498:MRU_RS01700
uniprot id: D3E007
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS00140
gene id: 634498:MRU_RS00140
uniprot id: D3E4I3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

634498:MRU RS01275
gene id: 634498:MRU_RS01275
uniprot id: D3DZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

634498:MRU RS04315
gene id: 634498:MRU_RS04315
uniprot id: D3E2E5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

634498:MRU RS08840
gene id: 634498:MRU_RS08840
uniprot id: D3DZ68
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

634498:MRU RS08630
gene id: 634498:MRU_RS08630
uniprot id: D3DZ25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

634498:MRU RS09125
gene id: 634498:MRU_RS09125
uniprot id: D3DZJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

634498:MRU RS08780
gene id: 634498:MRU_RS08780
uniprot id: D3DZ56
names: Similarity
messages: Belongs to the thioesterase PaaI family.

634498:MRU RS03540
gene id: 634498:MRU_RS03540
uniprot id: D3E1Y8
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

634498:MRU RS06425
gene id: 634498:MRU_RS06425
uniprot id: D3E3M4
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS10435
gene id: 634498:MRU_RS10435
uniprot id: D3E0V2
names: Similarity
messages: Belongs to the MvhD/VhuD family.

634498:MRU RS00915
gene id: 634498:MRU_RS00915
uniprot id: D3DZ79
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

634498:MRU RS06615
gene id: 634498:MRU_RS06615
uniprot id: D3E3R2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

634498:MRU RS10135
gene id: 634498:MRU_RS10135
uniprot id: D3E0F0
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS07330
gene id: 634498:MRU_RS07330
uniprot id: D3E455
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

634498:MRU RS08945
gene id: 634498:MRU_RS08945
uniprot id: D3DZG3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS09490
gene id: 634498:MRU_RS09490
uniprot id: D3DZR8
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.

634498:MRU RS07890
gene id: 634498:MRU_RS07890
uniprot id: D3E4N1
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

634498:MRU RS00050
gene id: 634498:MRU_RS00050
uniprot id: D3E4G6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

634498:MRU RS07455
gene id: 634498:MRU_RS07455
uniprot id: D3E480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

634498:MRU RS09180
gene id: 634498:MRU_RS09180
uniprot id: D3DZK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

634498:MRU RS00015
gene id: 634498:MRU_RS00015
uniprot id: D3E4F9
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS04635
gene id: 634498:MRU_RS04635
uniprot id: D3E2K9
names: Similarity
messages: Belongs to the MEMO1 family.

634498:MRU RS04640
gene id: 634498:MRU_RS04640
uniprot id: D3E2L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS06850
gene id: 634498:MRU_RS06850
uniprot id: D3E3V9
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS03445
gene id: 634498:MRU_RS03445
uniprot id: D3E1W8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

634498:MRU RS07810
gene id: 634498:MRU_RS07810
uniprot id: D3E4F3
names: Cofactor
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.

634498:MRU RS06965
gene id: 634498:MRU_RS06965
uniprot id: D3E3Y2
names: Similarity
messages: Belongs to the FTR family.

634498:MRU RS07470
gene id: 634498:MRU_RS07470
uniprot id: D3E483
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

634498:MRU RS09350
gene id: 634498:MRU_RS09350
uniprot id: D3DZP0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

634498:MRU RS11270
gene id: 634498:MRU_RS11270
uniprot id: D3E1E7
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

634498:MRU RS03145
gene id: 634498:MRU_RS03145
uniprot id: D3E1Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

634498:MRU RS05055
gene id: 634498:MRU_RS05055
uniprot id: D3E2U4
names: Similarity
messages: Belongs to the MtxX family.

634498:MRU RS03535
gene id: 634498:MRU_RS03535
uniprot id: D3E1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

634498:MRU RS09275
gene id: 634498:MRU_RS09275
uniprot id: D3DZM5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

634498:MRU RS08455
gene id: 634498:MRU_RS08455
uniprot id: D3DYY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Heterotetramer of 2 HacA and 2 HacB proteins.
messages: Hydro-lyase with broad substrate specificity for cis-unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4-tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4-tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B.

634498:MRU RS01995
gene id: 634498:MRU_RS01995
uniprot id: D3E0J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

634498:MRU RS04330
gene id: 634498:MRU_RS04330
uniprot id: D3E2E8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

634498:MRU RS06125
gene id: 634498:MRU_RS06125
uniprot id: D3E3G3
names: Similarity
messages: Belongs to the UPF0200 family.

634498:MRU RS06760
gene id: 634498:MRU_RS06760
uniprot id: D3E3U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

634498:MRU RS03500
gene id: 634498:MRU_RS03500
uniprot id: D3E1Y0
names: Similarity
messages: Belongs to the class-I fumarase family.

634498:MRU RS03010
gene id: 634498:MRU_RS03010
uniprot id: D3E1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS11235
gene id: 634498:MRU_RS11235
uniprot id: D3DZN2
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

634498:MRU RS00795
gene id: 634498:MRU_RS00795
uniprot id: D3DYU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

634498:MRU RS08640
gene id: 634498:MRU_RS08640
uniprot id: D3DZ27
names: Similarity
messages: Belongs to the peptidase U62 family.

634498:MRU RS02775
gene id: 634498:MRU_RS02775
uniprot id: D3E1I6
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

634498:MRU RS05105
gene id: 634498:MRU_RS05105
uniprot id: D3E2V5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

634498:MRU RS10550
gene id: 634498:MRU_RS10550
uniprot id: D3E0X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

634498:MRU RS04480
gene id: 634498:MRU_RS04480
uniprot id: D3E2H8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

634498:MRU RS08905
gene id: 634498:MRU_RS08905
uniprot id: D3DZF4
names: Similarity
messages: Belongs to the MoaB/Mog family.

634498:MRU RS01960
gene id: 634498:MRU_RS01960
uniprot id: D3E0J1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

634498:MRU RS00690
gene id: 634498:MRU_RS00690
uniprot id: D3DYR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

634498:MRU RS08520
gene id: 634498:MRU_RS08520
uniprot id: D3DZ02
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS07900
gene id: 634498:MRU_RS07900
uniprot id: D3E4N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

634498:MRU RS01730
gene id: 634498:MRU_RS01730
uniprot id: D3E013
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS07615
gene id: 634498:MRU_RS07615
uniprot id: D3E4B3
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS09500
gene id: 634498:MRU_RS09500
uniprot id: D3DZS0
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

634498:MRU RS09380
gene id: 634498:MRU_RS09380
uniprot id: D3DZP6
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

634498:MRU RS06015
gene id: 634498:MRU_RS06015
uniprot id: D3E3E1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS01945
gene id: 634498:MRU_RS01945
uniprot id: D3E0I8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

634498:MRU RS06475
gene id: 634498:MRU_RS06475
uniprot id: D3E3N4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

634498:MRU RS02305
gene id: 634498:MRU_RS02305
uniprot id: D3E0Q9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

634498:MRU RS07460
gene id: 634498:MRU_RS07460
uniprot id: D3E481
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

634498:MRU RS04390
gene id: 634498:MRU_RS04390
uniprot id: D3E2G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

634498:MRU RS04770
gene id: 634498:MRU_RS04770
uniprot id: D3E2N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

634498:MRU RS08655
gene id: 634498:MRU_RS08655
uniprot id: D3DZ30
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

634498:MRU RS04420
gene id: 634498:MRU_RS04420
uniprot id: D3E2G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

634498:MRU RS08525
gene id: 634498:MRU_RS08525
uniprot id: D3DZ03
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS06750
gene id: 634498:MRU_RS06750
uniprot id: D3E3T8
names: Function
messages: Probably involved in the biogenesis of the ribosome.

634498:MRU RS02445
gene id: 634498:MRU_RS02445
uniprot id: D3E149
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

634498:MRU RS07425
gene id: 634498:MRU_RS07425
uniprot id: D3E474
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

634498:MRU RS02565
gene id: 634498:MRU_RS02565
uniprot id: D3E173
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

634498:MRU RS10640
gene id: 634498:MRU_RS10640
uniprot id: D3E0Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

634498:MRU RS00535
gene id: 634498:MRU_RS00535
uniprot id: D3DYN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

634498:MRU RS10615
gene id: 634498:MRU_RS10615
uniprot id: D3E0Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

634498:MRU RS09910
gene id: 634498:MRU_RS09910
uniprot id: D3E0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

634498:MRU RS07835
gene id: 634498:MRU_RS07835
uniprot id: D3E4M5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

634498:MRU RS02045
gene id: 634498:MRU_RS02045
uniprot id: D3E0K7
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

634498:MRU RS06860
gene id: 634498:MRU_RS06860
uniprot id: D3E3W1
names: Similarity
messages: Belongs to the UPRTase family.

634498:MRU RS09705
gene id: 634498:MRU_RS09705
uniprot id: D3E065
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

634498:MRU RS05905
gene id: 634498:MRU_RS05905
uniprot id: D3E3B8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

634498:MRU RS07125
gene id: 634498:MRU_RS07125
uniprot id: D3E416
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

634498:MRU RS07720
gene id: 634498:MRU_RS07720
uniprot id: D3E4D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

634498:MRU RS07745
gene id: 634498:MRU_RS07745
uniprot id: D3E4E0
names: Similarity
messages: Belongs to the HypE family.

634498:MRU RS07695
gene id: 634498:MRU_RS07695
uniprot id: D3E4D0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

634498:MRU RS08090
gene id: 634498:MRU_RS08090
uniprot id: D3E4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

634498:MRU RS10345
gene id: 634498:MRU_RS10345
uniprot id: D3E0T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

634498:MRU RS07945
gene id: 634498:MRU_RS07945
uniprot id: D3E4P2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

634498:MRU RS06120
gene id: 634498:MRU_RS06120
uniprot id: D3E3G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

634498:MRU RS04475
gene id: 634498:MRU_RS04475
uniprot id: D3E2H7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

634498:MRU RS09190
gene id: 634498:MRU_RS09190
uniprot id: D3DZK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS05230
gene id: 634498:MRU_RS05230
uniprot id: D3E2Y0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the small carbamoyl-phosphate synthase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Catalyzes the synthesis of carbamoyl phosphate from ATP, ammonium and bicarbonate. Proceeds via a three-step mechanism, i.e. the phosphorylation of hydrogencarbonate to carboxyphosphate, a nucleophilic attack of ammonia on carboxyphosphate yielding carbamate, and the phosphorylation of carbamate forming carbamoyl phosphate.

634498:MRU RS05415
gene id: 634498:MRU_RS05415
uniprot id: D3E316
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS06130
gene id: 634498:MRU_RS06130
uniprot id: D3E3G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

634498:MRU RS08590
gene id: 634498:MRU_RS08590
uniprot id: D3DZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

634498:MRU RS04470
gene id: 634498:MRU_RS04470
uniprot id: D3E2H6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

634498:MRU RS07630
gene id: 634498:MRU_RS07630
uniprot id: D3E4B6
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

634498:MRU RS00995
gene id: 634498:MRU_RS00995
uniprot id: D3DZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

634498:MRU RS02370
gene id: 634498:MRU_RS02370
uniprot id: D3E135
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS09010
gene id: 634498:MRU_RS09010
uniprot id: D3DZH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS04455
gene id: 634498:MRU_RS04455
uniprot id: D3E2H3
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS05545
gene id: 634498:MRU_RS05545
uniprot id: D3E344
names: Similarity
messages: Belongs to the HerA family.

634498:MRU RS04345
gene id: 634498:MRU_RS04345
uniprot id: D3E2F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS08635
gene id: 634498:MRU_RS08635
uniprot id: D3DZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intimin/invasin family.
messages: Cell outer membrane
messages: Membrane

634498:MRU RS07685
gene id: 634498:MRU_RS07685
uniprot id: D3E4C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

634498:MRU RS09635
gene id: 634498:MRU_RS09635
uniprot id: D3E051
names: Similarity
names: Subunit
messages: Belongs to the methyl-coenzyme M reductase gamma subunit family.
messages: Hexamer of two alpha, two beta, and two gamma chains.
messages: MCR is a hexamer of two alpha, two beta, and two gamma chains, forming a dimer of heterotrimers.

634498:MRU RS00225
gene id: 634498:MRU_RS00225
uniprot id: D3E4K0
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS03195
gene id: 634498:MRU_RS03195
uniprot id: D3E1R7
names: Similarity
messages: Belongs to the ZPR1 family.

634498:MRU RS07300
gene id: 634498:MRU_RS07300
uniprot id: D3E450
names: Similarity
messages: Belongs to the UDPGP type 2 family.

634498:MRU RS03340
gene id: 634498:MRU_RS03340
uniprot id: D3E1U7
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

634498:MRU RS05175
gene id: 634498:MRU_RS05175
uniprot id: D3E2W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

634498:MRU RS08950
gene id: 634498:MRU_RS08950
uniprot id: D3DZG4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

634498:MRU RS00040
gene id: 634498:MRU_RS00040
uniprot id: D3E4G4
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS02130
gene id: 634498:MRU_RS02130
uniprot id: D3E0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intimin/invasin family.
messages: Cell outer membrane
messages: Membrane

634498:MRU RS02790
gene id: 634498:MRU_RS02790
uniprot id: D3E1I9
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

634498:MRU RS02135
gene id: 634498:MRU_RS02135
uniprot id: D3E0M5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

634498:MRU RS00830
gene id: 634498:MRU_RS00830
uniprot id: D3DYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS10700
gene id: 634498:MRU_RS10700
uniprot id: D3E103
names: Subcellular Location Annotation
messages: Secreted

634498:MRU RS05195
gene id: 634498:MRU_RS05195
uniprot id: D3E2X3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

634498:MRU RS02050
gene id: 634498:MRU_RS02050
uniprot id: D3E0K8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

634498:MRU RS03575
gene id: 634498:MRU_RS03575
uniprot id: D3E1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

634498:MRU RS06625
gene id: 634498:MRU_RS06625
uniprot id: D3E3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

634498:MRU RS05080
gene id: 634498:MRU_RS05080
uniprot id: D3E2V0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

634498:MRU RS06355
gene id: 634498:MRU_RS06355
uniprot id: D3E3K9
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS02065
gene id: 634498:MRU_RS02065
uniprot id: D3E0L1
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS04905
gene id: 634498:MRU_RS04905
uniprot id: D3E2R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

634498:MRU RS04805
gene id: 634498:MRU_RS04805
uniprot id: D3E2P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

634498:MRU RS03335
gene id: 634498:MRU_RS03335
uniprot id: D3E1U6
names: Cofactor
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.

634498:MRU RS04575
gene id: 634498:MRU_RS04575
uniprot id: D3E2J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS04250
gene id: 634498:MRU_RS04250
uniprot id: D3E2D1
names: Similarity
messages: Belongs to the class-I fumarase family.

634498:MRU RS09215
gene id: 634498:MRU_RS09215
uniprot id: D3DZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

634498:MRU RS03690
gene id: 634498:MRU_RS03690
uniprot id: D3E218
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

634498:MRU RS05345
gene id: 634498:MRU_RS05345
uniprot id: D3E302
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

634498:MRU RS08135
gene id: 634498:MRU_RS08135
uniprot id: D3E4T3
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS00335
gene id: 634498:MRU_RS00335
uniprot id: D3E4M1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

634498:MRU RS07420
gene id: 634498:MRU_RS07420
uniprot id: D3E473
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

634498:MRU RS07430
gene id: 634498:MRU_RS07430
uniprot id: D3E475
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

634498:MRU RS04580
gene id: 634498:MRU_RS04580
uniprot id: D3E2J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Binds 1 [3Fe-4S] cluster.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

634498:MRU RS00525
gene id: 634498:MRU_RS00525
uniprot id: D3DYN5
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

634498:MRU RS09015
gene id: 634498:MRU_RS09015
uniprot id: D3DZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

634498:MRU RS09940
gene id: 634498:MRU_RS09940
uniprot id: D3E0B1
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

634498:MRU RS06705
gene id: 634498:MRU_RS06705
uniprot id: D3E3S9
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS01320
gene id: 634498:MRU_RS01320
uniprot id: D3DZE4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS06985
gene id: 634498:MRU_RS06985
uniprot id: D3E3Y7
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

634498:MRU RS04380
gene id: 634498:MRU_RS04380
uniprot id: D3E2F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

634498:MRU RS00835
gene id: 634498:MRU_RS00835
uniprot id: D3DYU8
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

634498:MRU RS05495
gene id: 634498:MRU_RS05495
uniprot id: D3E332
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

634498:MRU RS01015
gene id: 634498:MRU_RS01015
uniprot id: D3DZ99
names: Similarity
messages: Belongs to the UPF0107 family.

634498:MRU RS05420
gene id: 634498:MRU_RS05420
uniprot id: D3E317
names: Similarity
messages: Belongs to the intimin/invasin family.

634498:MRU RS05925
gene id: 634498:MRU_RS05925
uniprot id: D3E3C2
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

634498:MRU RS07385
gene id: 634498:MRU_RS07385
uniprot id: D3E466
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS00885
gene id: 634498:MRU_RS00885
uniprot id: D3DYV8
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

634498:MRU RS10955
gene id: 634498:MRU_RS10955
uniprot id: D3E1E6
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

634498:MRU RS02570
gene id: 634498:MRU_RS02570
uniprot id: D3E174
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

634498:MRU RS09220
gene id: 634498:MRU_RS09220
uniprot id: D3DZL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

634498:MRU RS08020
gene id: 634498:MRU_RS08020
uniprot id: D3E4Q8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

634498:MRU RS00485
gene id: 634498:MRU_RS00485
uniprot id: D3DYM7
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS00990
gene id: 634498:MRU_RS00990
uniprot id: D3DZ94
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

634498:MRU RS08460
gene id: 634498:MRU_RS08460
uniprot id: D3DYZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

634498:MRU RS07355
gene id: 634498:MRU_RS07355
uniprot id: D3E460
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

634498:MRU RS03240
gene id: 634498:MRU_RS03240
uniprot id: D3E1S6
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS01935
gene id: 634498:MRU_RS01935
uniprot id: D3E0I6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: SAH is a product of SAM methyltransferases and is known to be a feedback inhibitor of these enzymes. As a result of this inhibition, organisms have evolved efficient enzymes to metabolize SAH via different pathways. The pathway found in methanogens differs from the canonical pathway, it uses the deamination of S-adenosyl-L-homocysteine to form S-inosyl-L-homocysteine for the regeneration of SAM from S-adenosyl-L-homocysteine.

634498:MRU RS09230
gene id: 634498:MRU_RS09230
uniprot id: D3DZL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.

634498:MRU RS02605
gene id: 634498:MRU_RS02605
uniprot id: D3E181
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

634498:MRU RS06430
gene id: 634498:MRU_RS06430
uniprot id: D3E3M5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

634498:MRU RS05665
gene id: 634498:MRU_RS05665
uniprot id: D3E368
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

634498:MRU RS10245
gene id: 634498:MRU_RS10245
uniprot id: D3E0R5
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

634498:MRU RS08920
gene id: 634498:MRU_RS08920
uniprot id: D3DZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

634498:MRU RS05020
gene id: 634498:MRU_RS05020
uniprot id: D3E2T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

634498:MRU RS06080
gene id: 634498:MRU_RS06080
uniprot id: D3E3F4
names: Similarity
messages: Belongs to the DMRL synthase family.

634498:MRU RS05305
gene id: 634498:MRU_RS05305
uniprot id: D3E2Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

634498:MRU RS10600
gene id: 634498:MRU_RS10600
uniprot id: D3E0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
messages: Cell membrane
messages: Membrane

634498:MRU RS07340
gene id: 634498:MRU_RS07340
uniprot id: D3E457
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

634498:MRU RS09895
gene id: 634498:MRU_RS09895
uniprot id: D3E0A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

634498:MRU RS06300
gene id: 634498:MRU_RS06300
uniprot id: D3E3J8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

634498:MRU RS04305
gene id: 634498:MRU_RS04305
uniprot id: D3E2E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

634498:MRU RS06865
gene id: 634498:MRU_RS06865
uniprot id: D3E3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

634498:MRU RS04375
gene id: 634498:MRU_RS04375
uniprot id: D3E2F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

634498:MRU RS01280
gene id: 634498:MRU_RS01280
uniprot id: D3DZD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

634498:MRU RS08555
gene id: 634498:MRU_RS08555
uniprot id: D3DZ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

634498:MRU RS08355
gene id: 634498:MRU_RS08355
uniprot id: D3DYX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

634498:MRU RS06785
gene id: 634498:MRU_RS06785
uniprot id: D3E3U6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

634498:MRU RS07435
gene id: 634498:MRU_RS07435
uniprot id: D3E476
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

634498:MRU RS09960
gene id: 634498:MRU_RS09960
uniprot id: D3E0B5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS01055
gene id: 634498:MRU_RS01055
uniprot id: D3DZA7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS08365
gene id: 634498:MRU_RS08365
uniprot id: D3DYX3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

634498:MRU RS04350
gene id: 634498:MRU_RS04350
uniprot id: D3E2F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

634498:MRU RS09435
gene id: 634498:MRU_RS09435
uniprot id: D3DZQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

634498:MRU RS03650
gene id: 634498:MRU_RS03650
uniprot id: D3E209
names: Similarity
messages: Belongs to the UPF0145 family.

634498:MRU RS06410
gene id: 634498:MRU_RS06410
uniprot id: D3E3M1
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

634498:MRU RS08105
gene id: 634498:MRU_RS08105
uniprot id: D3E4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
messages: Cytoplasm

634498:MRU RS08685
gene id: 634498:MRU_RS08685
uniprot id: D3DZ36
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

634498:MRU RS01315
gene id: 634498:MRU_RS01315
uniprot id: D3DZE3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

634498:MRU RS08705
gene id: 634498:MRU_RS08705
uniprot id: D3DZ41
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

634498:MRU RS04295
gene id: 634498:MRU_RS04295
uniprot id: D3E2E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

634498:MRU RS00700
gene id: 634498:MRU_RS00700
uniprot id: D3DYR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

634498:MRU RS05340
gene id: 634498:MRU_RS05340
uniprot id: D3E301
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

634498:MRU RS03545
gene id: 634498:MRU_RS03545
uniprot id: D3E1Y9
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

634498:MRU RS07010
gene id: 634498:MRU_RS07010
uniprot id: D3E3Z2
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS09030
gene id: 634498:MRU_RS09030
uniprot id: D3DZI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

634498:MRU RS00490
gene id: 634498:MRU_RS00490
uniprot id: D3DYM8
names: Function
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

634498:MRU RS08060
gene id: 634498:MRU_RS08060
uniprot id: D3E4R6
names: Similarity
messages: Belongs to the TlyA family.

634498:MRU RS09810
gene id: 634498:MRU_RS09810
uniprot id: D3E086
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

634498:MRU RS04435
gene id: 634498:MRU_RS04435
uniprot id: D3E2G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

634498:MRU RS02635
gene id: 634498:MRU_RS02635
uniprot id: D3E188
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

634498:MRU RS00880
gene id: 634498:MRU_RS00880
uniprot id: D3DYV7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

634498:MRU RS02730
gene id: 634498:MRU_RS02730
uniprot id: D3E1A7
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS11030
gene id: 634498:MRU_RS11030
uniprot id: D3E1G2
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS04260
gene id: 634498:MRU_RS04260
uniprot id: D3E2D3
names: Similarity
messages: Belongs to the intimin/invasin family.
messages: Belongs to the peptidase C1 family.

634498:MRU RS04860
gene id: 634498:MRU_RS04860
uniprot id: D3E2Q4
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS06755
gene id: 634498:MRU_RS06755
uniprot id: D3E3T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

634498:MRU RS09200
gene id: 634498:MRU_RS09200
uniprot id: D3DZL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

634498:MRU RS04210
gene id: 634498:MRU_RS04210
uniprot id: D3E2C4
names: Similarity
messages: Belongs to the UPF0173 family.

634498:MRU RS09605
gene id: 634498:MRU_RS09605
uniprot id: D3E045
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtrA family.
messages: Binds 1 5-hydroxybenzimidazolylcobamide group.
messages: Cell membrane
messages: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
messages: The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

634498:MRU RS05555
gene id: 634498:MRU_RS05555
uniprot id: D3E346
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

634498:MRU RS00940
gene id: 634498:MRU_RS00940
uniprot id: D3DZ84
names: Subcellular Location Annotation
messages: Membrane

634498:MRU RS06280
gene id: 634498:MRU_RS06280
uniprot id: D3E3J4
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

634498:MRU RS00530
gene id: 634498:MRU_RS00530
uniprot id: D3DYN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

634498:MRU RS03530
gene id: 634498:MRU_RS03530
uniprot id: D3E1Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

634498:MRU RS06840
gene id: 634498:MRU_RS06840
uniprot id: D3E3V7
names: Similarity
messages: Belongs to the peptidase C59 family.

634498:MRU RS07895
gene id: 634498:MRU_RS07895
uniprot id: D3E4N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

634498:MRU RS08200
gene id: 634498:MRU_RS08200
uniprot id: D3E4U6
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

634498:MRU RS04085
gene id: 634498:MRU_RS04085
uniprot id: D3E2A0
names: Similarity
messages: Belongs to the glutamate synthase family.

634498:MRU RS06295
gene id: 634498:MRU_RS06295
uniprot id: D3E3J7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

634498:MRU RS04585
gene id: 634498:MRU_RS04585
uniprot id: D3E2J9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

634498:MRU RS04405
gene id: 634498:MRU_RS04405
uniprot id: D3E2G3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

634498:MRU RS09120
gene id: 634498:MRU_RS09120
uniprot id: D3DZJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

634498:MRU RS01345
gene id: 634498:MRU_RS01345
uniprot id: D3DZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

634498:MRU RS05285
gene id: 634498:MRU_RS05285
uniprot id: D3E2Z1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

634498:MRU RS10465
gene id: 634498:MRU_RS10465
uniprot id: D3E0V8
names: Similarity
messages: Belongs to the glutamate synthase family.