633148:TAGG RS04655
gene id: 633148:TAGG_RS04655
uniprot id: D5U259
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

633148:TAGG RS04735
gene id: 633148:TAGG_RS04735
uniprot id: D5U273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

633148:TAGG RS04490
gene id: 633148:TAGG_RS04490
uniprot id: D5U228
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

633148:TAGG RS06730
gene id: 633148:TAGG_RS06730
uniprot id: D5U394
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

633148:TAGG RS02255
gene id: 633148:TAGG_RS02255
uniprot id: D5U0S3
names: Similarity
messages: Belongs to the AOR/FOR family.

633148:TAGG RS04185
gene id: 633148:TAGG_RS04185
uniprot id: D5U1W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

633148:TAGG RS00725
gene id: 633148:TAGG_RS00725
uniprot id: D5TZX0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

633148:TAGG RS02310
gene id: 633148:TAGG_RS02310
uniprot id: D5U0T4
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

633148:TAGG RS06285
gene id: 633148:TAGG_RS06285
uniprot id: D5U312
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

633148:TAGG RS02225
gene id: 633148:TAGG_RS02225
uniprot id: D5U0R7
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

633148:TAGG RS04240
gene id: 633148:TAGG_RS04240
uniprot id: D5U1Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

633148:TAGG RS05790
gene id: 633148:TAGG_RS05790
uniprot id: D5U2S2
names: Similarity
messages: Belongs to the thymidylate kinase family.

633148:TAGG RS00135
gene id: 633148:TAGG_RS00135
uniprot id: D5TZK7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

633148:TAGG RS05835
gene id: 633148:TAGG_RS05835
uniprot id: D5U2T1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

633148:TAGG RS03105
gene id: 633148:TAGG_RS03105
uniprot id: D5U197
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

633148:TAGG RS06570
gene id: 633148:TAGG_RS06570
uniprot id: D5U365
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

633148:TAGG RS03235
gene id: 633148:TAGG_RS03235
uniprot id: D5U1C4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

633148:TAGG RS04080
gene id: 633148:TAGG_RS04080
uniprot id: D5U1U5
names: Subcellular Location Annotation
messages: Nucleus

633148:TAGG RS04325
gene id: 633148:TAGG_RS04325
uniprot id: D5U1Z7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

633148:TAGG RS04255
gene id: 633148:TAGG_RS04255
uniprot id: D5U1Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

633148:TAGG RS01885
gene id: 633148:TAGG_RS01885
uniprot id: D5U0J8
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS06540
gene id: 633148:TAGG_RS06540
uniprot id: D5U359
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

633148:TAGG RS06725
gene id: 633148:TAGG_RS06725
uniprot id: D5U393
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

633148:TAGG RS00110
gene id: 633148:TAGG_RS00110
uniprot id: D5TZK2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

633148:TAGG RS01150
gene id: 633148:TAGG_RS01150
uniprot id: D5U054
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer composed of an alpha and a beta subunit.
messages: Heterodimer of the IorA and IorB subunits.

633148:TAGG RS06940
gene id: 633148:TAGG_RS06940
uniprot id: D5U3D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

633148:TAGG RS01585
gene id: 633148:TAGG_RS01585
uniprot id: D5U0D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

633148:TAGG RS05300
gene id: 633148:TAGG_RS05300
uniprot id: D5U2H8
names: Similarity
messages: Belongs to the HypE family.

633148:TAGG RS00785
gene id: 633148:TAGG_RS00785
uniprot id: D5TZY2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

633148:TAGG RS03095
gene id: 633148:TAGG_RS03095
uniprot id: D5U195
names: Similarity
messages: Belongs to the HupF/HypC family.

633148:TAGG RS04620
gene id: 633148:TAGG_RS04620
uniprot id: D5U252
names: Similarity
messages: Belongs to the PDCD5 family.

633148:TAGG RS06445
gene id: 633148:TAGG_RS06445
uniprot id: D5U341
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

633148:TAGG RS04495
gene id: 633148:TAGG_RS04495
uniprot id: D5U229
names: Similarity
messages: Belongs to the archease family.

633148:TAGG RS05075
gene id: 633148:TAGG_RS05075
uniprot id: D5U2D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

633148:TAGG RS06640
gene id: 633148:TAGG_RS06640
uniprot id: D5U377
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS04265
gene id: 633148:TAGG_RS04265
uniprot id: D5U1Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS06235
gene id: 633148:TAGG_RS06235
uniprot id: D5U303
names: Similarity
messages: Belongs to the pyruvate kinase family.

633148:TAGG RS04220
gene id: 633148:TAGG_RS04220
uniprot id: D5U1X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS02305
gene id: 633148:TAGG_RS02305
uniprot id: D5U0T3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

633148:TAGG RS05855
gene id: 633148:TAGG_RS05855
uniprot id: D5U2T3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS05135
gene id: 633148:TAGG_RS05135
uniprot id: D5U2E9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS01945
gene id: 633148:TAGG_RS01945
uniprot id: D5U0L1
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

633148:TAGG RS05995
gene id: 633148:TAGG_RS05995
uniprot id: D5U2V9
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

633148:TAGG RS02535
gene id: 633148:TAGG_RS02535
uniprot id: D5U0X9
names: Similarity
messages: Belongs to the HypD family.

633148:TAGG RS06680
gene id: 633148:TAGG_RS06680
uniprot id: D5U385
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

633148:TAGG RS02525
gene id: 633148:TAGG_RS02525
uniprot id: D5U0X7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

633148:TAGG RS06195
gene id: 633148:TAGG_RS06195
uniprot id: D5U2Z6
names: Similarity
messages: Belongs to the UPF0173 family.

633148:TAGG RS03640
gene id: 633148:TAGG_RS03640
uniprot id: D5U1K5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

633148:TAGG RS00440
gene id: 633148:TAGG_RS00440
uniprot id: D5TZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

633148:TAGG RS06585
gene id: 633148:TAGG_RS06585
uniprot id: D5U368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

633148:TAGG RS04215
gene id: 633148:TAGG_RS04215
uniprot id: D5U1X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

633148:TAGG RS03325
gene id: 633148:TAGG_RS03325
uniprot id: D5U1E2
names: Subunit
messages: Homodimer.

633148:TAGG RS02065
gene id: 633148:TAGG_RS02065
uniprot id: D5U0N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

633148:TAGG RS03055
gene id: 633148:TAGG_RS03055
uniprot id: D5U187
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

633148:TAGG RS07085
gene id: 633148:TAGG_RS07085
uniprot id: D5U3G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

633148:TAGG RS03480
gene id: 633148:TAGG_RS03480
uniprot id: D5U1H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

633148:TAGG RS04880
gene id: 633148:TAGG_RS04880
uniprot id: D5U2A0
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS02450
gene id: 633148:TAGG_RS02450
uniprot id: D5U0W2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

633148:TAGG RS06920
gene id: 633148:TAGG_RS06920
uniprot id: D5U3D1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS00865
gene id: 633148:TAGG_RS00865
uniprot id: D5TZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

633148:TAGG RS07050
gene id: 633148:TAGG_RS07050
uniprot id: D5U3F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

633148:TAGG RS04285
gene id: 633148:TAGG_RS04285
uniprot id: D5U1Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

633148:TAGG RS07030
gene id: 633148:TAGG_RS07030
uniprot id: D5U3F3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

633148:TAGG RS04695
gene id: 633148:TAGG_RS04695
uniprot id: D5U267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

633148:TAGG RS03750
gene id: 633148:TAGG_RS03750
uniprot id: D5U1M7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

633148:TAGG RS04095
gene id: 633148:TAGG_RS04095
uniprot id: D5U1U9
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

633148:TAGG RS07015
gene id: 633148:TAGG_RS07015
uniprot id: D5U3F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

633148:TAGG RS02580
gene id: 633148:TAGG_RS02580
uniprot id: D5U0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

633148:TAGG RS03285
gene id: 633148:TAGG_RS03285
uniprot id: D5U1D4
names: Similarity
messages: Belongs to the Nth/MutY family.

633148:TAGG RS04270
gene id: 633148:TAGG_RS04270
uniprot id: D5U1Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

633148:TAGG RS00335
gene id: 633148:TAGG_RS00335
uniprot id: D5TZP5
names: Subcellular Location Annotation
messages: Cell membrane

633148:TAGG RS00720
gene id: 633148:TAGG_RS00720
uniprot id: D5TZW9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

633148:TAGG RS05715
gene id: 633148:TAGG_RS05715
uniprot id: D5U2Q9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

633148:TAGG RS03240
gene id: 633148:TAGG_RS03240
uniprot id: D5U1C5
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00710
gene id: 633148:TAGG_RS00710
uniprot id: D5TZW7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

633148:TAGG RS02490
gene id: 633148:TAGG_RS02490
uniprot id: D5U0X0
names: Similarity
messages: Belongs to the DtxR/MntR family.

633148:TAGG RS02425
gene id: 633148:TAGG_RS02425
uniprot id: D5U0V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

633148:TAGG RS01600
gene id: 633148:TAGG_RS01600
uniprot id: D5U0E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

633148:TAGG RS05655
gene id: 633148:TAGG_RS05655
uniprot id: D5U2P9
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS03575
gene id: 633148:TAGG_RS03575
uniprot id: D5U1J2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS06705
gene id: 633148:TAGG_RS06705
uniprot id: D5U389
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

633148:TAGG RS01105
gene id: 633148:TAGG_RS01105
uniprot id: D5U046
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

633148:TAGG RS00155
gene id: 633148:TAGG_RS00155
uniprot id: D5TZL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

633148:TAGG RS06260
gene id: 633148:TAGG_RS06260
uniprot id: D5U307
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

633148:TAGG RS03510
gene id: 633148:TAGG_RS03510
uniprot id: D5U1H9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

633148:TAGG RS02805
gene id: 633148:TAGG_RS02805
uniprot id: D5U132
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

633148:TAGG RS05905
gene id: 633148:TAGG_RS05905
uniprot id: D5U2U2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

633148:TAGG RS04045
gene id: 633148:TAGG_RS04045
uniprot id: D5U1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

633148:TAGG RS02035
gene id: 633148:TAGG_RS02035
uniprot id: D5U0M8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS06775
gene id: 633148:TAGG_RS06775
uniprot id: D5U3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

633148:TAGG RS02695
gene id: 633148:TAGG_RS02695
uniprot id: D5U110
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

633148:TAGG RS03190
gene id: 633148:TAGG_RS03190
uniprot id: D5U1B5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

633148:TAGG RS01555
gene id: 633148:TAGG_RS01555
uniprot id: D5U0D3
names: Similarity
messages: Belongs to the carbamate kinase family.

633148:TAGG RS02085
gene id: 633148:TAGG_RS02085
uniprot id: D5U0N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

633148:TAGG RS00145
gene id: 633148:TAGG_RS00145
uniprot id: D5TZK9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

633148:TAGG RS06495
gene id: 633148:TAGG_RS06495
uniprot id: D5U351
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

633148:TAGG RS03915
gene id: 633148:TAGG_RS03915
uniprot id: D5U1R2
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS02495
gene id: 633148:TAGG_RS02495
uniprot id: D5U0X1
names: Similarity
messages: Belongs to the glutaredoxin family.

633148:TAGG RS00825
gene id: 633148:TAGG_RS00825
uniprot id: D5TZZ0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

633148:TAGG RS00650
gene id: 633148:TAGG_RS00650
uniprot id: D5TZV6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

633148:TAGG RS03165
gene id: 633148:TAGG_RS03165
uniprot id: D5U1A9
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00820
gene id: 633148:TAGG_RS00820
uniprot id: D5TZY9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

633148:TAGG RS05395
gene id: 633148:TAGG_RS05395
uniprot id: D5U2J8
names: Similarity
messages: Belongs to the diphthine synthase family.

633148:TAGG RS05630
gene id: 633148:TAGG_RS05630
uniprot id: D5U2P4
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS01285
gene id: 633148:TAGG_RS01285
uniprot id: D5U081
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

633148:TAGG RS06950
gene id: 633148:TAGG_RS06950
uniprot id: D5U3D7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

633148:TAGG RS00095
gene id: 633148:TAGG_RS00095
uniprot id: D5TZJ9
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS07040
gene id: 633148:TAGG_RS07040
uniprot id: D5U3F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS02570
gene id: 633148:TAGG_RS02570
uniprot id: D5U0Y6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

633148:TAGG RS04250
gene id: 633148:TAGG_RS04250
uniprot id: D5U1Y2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

633148:TAGG RS00210
gene id: 633148:TAGG_RS00210
uniprot id: D5TZM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

633148:TAGG RS03145
gene id: 633148:TAGG_RS03145
uniprot id: D5U1A5
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00760
gene id: 633148:TAGG_RS00760
uniprot id: D5TZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

633148:TAGG RS02735
gene id: 633148:TAGG_RS02735
uniprot id: D5U118
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS06310
gene id: 633148:TAGG_RS06310
uniprot id: D5U317
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homodimer.

633148:TAGG RS03985
gene id: 633148:TAGG_RS03985
uniprot id: D5U1S6
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

633148:TAGG RS01395
gene id: 633148:TAGG_RS01395
uniprot id: D5U0A2
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

633148:TAGG RS06915
gene id: 633148:TAGG_RS06915
uniprot id: D5U3D0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.

633148:TAGG RS00455
gene id: 633148:TAGG_RS00455
uniprot id: D5TZR9
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

633148:TAGG RS06160
gene id: 633148:TAGG_RS06160
uniprot id: D5U2Z0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

633148:TAGG RS00800
gene id: 633148:TAGG_RS00800
uniprot id: D5TZY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

633148:TAGG RS05170
gene id: 633148:TAGG_RS05170
uniprot id: D5U2F6
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00950
gene id: 633148:TAGG_RS00950
uniprot id: D5U015
names: Similarity
messages: Belongs to the phosphohexose mutase family.

633148:TAGG RS04930
gene id: 633148:TAGG_RS04930
uniprot id: D5U2B1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

633148:TAGG RS00790
gene id: 633148:TAGG_RS00790
uniprot id: D5TZY3
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

633148:TAGG RS05175
gene id: 633148:TAGG_RS05175
uniprot id: D5U2F7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

633148:TAGG RS00450
gene id: 633148:TAGG_RS00450
uniprot id: D5TZR8
names: Similarity
messages: Belongs to the UPF0216 family.

633148:TAGG RS06015
gene id: 633148:TAGG_RS06015
uniprot id: D5U2W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

633148:TAGG RS05385
gene id: 633148:TAGG_RS05385
uniprot id: D5U2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

633148:TAGG RS04275
gene id: 633148:TAGG_RS04275
uniprot id: D5U1Y7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

633148:TAGG RS06505
gene id: 633148:TAGG_RS06505
uniprot id: D5U353
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

633148:TAGG RS02070
gene id: 633148:TAGG_RS02070
uniprot id: D5U0N5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

633148:TAGG RS01975
gene id: 633148:TAGG_RS01975
uniprot id: D5U0L7
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

633148:TAGG RS03380
gene id: 633148:TAGG_RS03380
uniprot id: D5U1F3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

633148:TAGG RS01970
gene id: 633148:TAGG_RS01970
uniprot id: D5U0L6
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

633148:TAGG RS06905
gene id: 633148:TAGG_RS06905
uniprot id: D5U3C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

633148:TAGG RS07000
gene id: 633148:TAGG_RS07000
uniprot id: D5U3E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS02935
gene id: 633148:TAGG_RS02935
uniprot id: D5U163
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

633148:TAGG RS05430
gene id: 633148:TAGG_RS05430
uniprot id: D5U2K5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Belongs to the glycosyl hydrolase 3 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

633148:TAGG RS01570
gene id: 633148:TAGG_RS01570
uniprot id: D5U0D6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

633148:TAGG RS03315
gene id: 633148:TAGG_RS03315
uniprot id: D5U1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

633148:TAGG RS06455
gene id: 633148:TAGG_RS06455
uniprot id: D5U343
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

633148:TAGG RS01070
gene id: 633148:TAGG_RS01070
uniprot id: D5U039
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00525
gene id: 633148:TAGG_RS00525
uniprot id: D5TZT3
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

633148:TAGG RS00560
gene id: 633148:TAGG_RS00560
uniprot id: D5TZT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS03255
gene id: 633148:TAGG_RS03255
uniprot id: D5U1C8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

633148:TAGG RS05575
gene id: 633148:TAGG_RS05575
uniprot id: D5U2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

633148:TAGG RS04635
gene id: 633148:TAGG_RS04635
uniprot id: D5U255
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

633148:TAGG RS04685
gene id: 633148:TAGG_RS04685
uniprot id: D5U265
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

633148:TAGG RS05960
gene id: 633148:TAGG_RS05960
uniprot id: D5U2V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

633148:TAGG RS01465
gene id: 633148:TAGG_RS01465
uniprot id: D5U0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

633148:TAGG RS06315
gene id: 633148:TAGG_RS06315
uniprot id: D5U318
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

633148:TAGG RS05155
gene id: 633148:TAGG_RS05155
uniprot id: D5U2F3
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS02815
gene id: 633148:TAGG_RS02815
uniprot id: D5U134
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

633148:TAGG RS06305
gene id: 633148:TAGG_RS06305
uniprot id: D5U316
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

633148:TAGG RS00600
gene id: 633148:TAGG_RS00600
uniprot id: D5TZU7
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS01515
gene id: 633148:TAGG_RS01515
uniprot id: D5U0C5
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

633148:TAGG RS00160
gene id: 633148:TAGG_RS00160
uniprot id: D5TZL2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

633148:TAGG RS04300
gene id: 633148:TAGG_RS04300
uniprot id: D5U1Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

633148:TAGG RS06295
gene id: 633148:TAGG_RS06295
uniprot id: D5U314
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

633148:TAGG RS06150
gene id: 633148:TAGG_RS06150
uniprot id: D5U2Y8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

633148:TAGG RS06600
gene id: 633148:TAGG_RS06600
uniprot id: D5U370
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

633148:TAGG RS04055
gene id: 633148:TAGG_RS04055
uniprot id: D5U1U1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

633148:TAGG RS01680
gene id: 633148:TAGG_RS01680
uniprot id: D5U0F8
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

633148:TAGG RS03300
gene id: 633148:TAGG_RS03300
uniprot id: D5U1D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

633148:TAGG RS06790
gene id: 633148:TAGG_RS06790
uniprot id: D5U3A5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

633148:TAGG RS03460
gene id: 633148:TAGG_RS03460
uniprot id: D5U1G9
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

633148:TAGG RS02635
gene id: 633148:TAGG_RS02635
uniprot id: D5U0Z8
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS06740
gene id: 633148:TAGG_RS06740
uniprot id: D5U396
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

633148:TAGG RS05620
gene id: 633148:TAGG_RS05620
uniprot id: D5U2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

633148:TAGG RS02350
gene id: 633148:TAGG_RS02350
uniprot id: D5U0U2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

633148:TAGG RS05900
gene id: 633148:TAGG_RS05900
uniprot id: D5U2U1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

633148:TAGG RS00430
gene id: 633148:TAGG_RS00430
uniprot id: D5TZR4
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

633148:TAGG RS05050
gene id: 633148:TAGG_RS05050
uniprot id: D5U2D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

633148:TAGG RS01540
gene id: 633148:TAGG_RS01540
uniprot id: D5U0D0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

633148:TAGG RS01090
gene id: 633148:TAGG_RS01090
uniprot id: D5U043
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

633148:TAGG RS00985
gene id: 633148:TAGG_RS00985
uniprot id: D5U022
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

633148:TAGG RS00975
gene id: 633148:TAGG_RS00975
uniprot id: D5U020
names: Similarity
messages: Belongs to the RuvB family.

633148:TAGG RS00860
gene id: 633148:TAGG_RS00860
uniprot id: D5TZZ7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

633148:TAGG RS02030
gene id: 633148:TAGG_RS02030
uniprot id: D5U0M7
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS05985
gene id: 633148:TAGG_RS05985
uniprot id: D5U2V7
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

633148:TAGG RS04225
gene id: 633148:TAGG_RS04225
uniprot id: D5U1X7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

633148:TAGG RS02420
gene id: 633148:TAGG_RS02420
uniprot id: D5U0V6
names: Similarity
messages: Belongs to the peptidase U62 family.

633148:TAGG RS05145
gene id: 633148:TAGG_RS05145
uniprot id: D5U2F1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS01365
gene id: 633148:TAGG_RS01365
uniprot id: D5U096
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

633148:TAGG RS00005
gene id: 633148:TAGG_RS00005
uniprot id: D5TZI4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

633148:TAGG RS04795
gene id: 633148:TAGG_RS04795
uniprot id: D5U285
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

633148:TAGG RS00585
gene id: 633148:TAGG_RS00585
uniprot id: D5TZU4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS00575
gene id: 633148:TAGG_RS00575
uniprot id: D5TZU2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS00545
gene id: 633148:TAGG_RS00545
uniprot id: D5TZT6
names: Similarity
messages: Belongs to the AOR/FOR family.

633148:TAGG RS03760
gene id: 633148:TAGG_RS03760
uniprot id: D5U1M9
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS05990
gene id: 633148:TAGG_RS05990
uniprot id: D5U2V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

633148:TAGG RS01015
gene id: 633148:TAGG_RS01015
uniprot id: D5U028
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

633148:TAGG RS04820
gene id: 633148:TAGG_RS04820
uniprot id: D5U290
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

633148:TAGG RS00050
gene id: 633148:TAGG_RS00050
uniprot id: D5TZJ0
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

633148:TAGG RS00805
gene id: 633148:TAGG_RS00805
uniprot id: D5TZY6
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

633148:TAGG RS02760
gene id: 633148:TAGG_RS02760
uniprot id: D5U123
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

633148:TAGG RS02955
gene id: 633148:TAGG_RS02955
uniprot id: D5U167
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS04915
gene id: 633148:TAGG_RS04915
uniprot id: D5U2A8
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

633148:TAGG RS03150
gene id: 633148:TAGG_RS03150
uniprot id: D5U1A6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS02775
gene id: 633148:TAGG_RS02775
uniprot id: D5U126
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

633148:TAGG RS04010
gene id: 633148:TAGG_RS04010
uniprot id: D5U1T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

633148:TAGG RS04775
gene id: 633148:TAGG_RS04775
uniprot id: D5U281
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS01740
gene id: 633148:TAGG_RS01740
uniprot id: D5U0G9
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

633148:TAGG RS00660
gene id: 633148:TAGG_RS00660
uniprot id: D5TZV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

633148:TAGG RS03015
gene id: 633148:TAGG_RS03015
uniprot id: D5U179
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

633148:TAGG RS00410
gene id: 633148:TAGG_RS00410
uniprot id: D5TZR0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

633148:TAGG RS05685
gene id: 633148:TAGG_RS05685
uniprot id: D5U2Q4
names: Similarity
messages: Belongs to the UPF0282 family.

633148:TAGG RS03135
gene id: 633148:TAGG_RS03135
uniprot id: D5U1A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS06290
gene id: 633148:TAGG_RS06290
uniprot id: D5U313
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

633148:TAGG RS06980
gene id: 633148:TAGG_RS06980
uniprot id: D5U3E3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

633148:TAGG RS06930
gene id: 633148:TAGG_RS06930
uniprot id: D5U3D3
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

633148:TAGG RS06900
gene id: 633148:TAGG_RS06900
uniprot id: D5U3C7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS04280
gene id: 633148:TAGG_RS04280
uniprot id: D5U1Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

633148:TAGG RS05695
gene id: 633148:TAGG_RS05695
uniprot id: D5U2Q6
names: Subcellular Location Annotation
messages: Encapsulin nanocompartment

633148:TAGG RS03785
gene id: 633148:TAGG_RS03785
uniprot id: D5U1N5
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

633148:TAGG RS06085
gene id: 633148:TAGG_RS06085
uniprot id: D5U2X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

633148:TAGG RS05580
gene id: 633148:TAGG_RS05580
uniprot id: D5U2N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

633148:TAGG RS02235
gene id: 633148:TAGG_RS02235
uniprot id: D5U0R9
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS04130
gene id: 633148:TAGG_RS04130
uniprot id: D5U1V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.

633148:TAGG RS00415
gene id: 633148:TAGG_RS00415
uniprot id: D5TZR1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

633148:TAGG RS05925
gene id: 633148:TAGG_RS05925
uniprot id: D5U2U6
names: Similarity
messages: Belongs to the UPF0111 family.

633148:TAGG RS04260
gene id: 633148:TAGG_RS04260
uniprot id: D5U1Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS04630
gene id: 633148:TAGG_RS04630
uniprot id: D5U254
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

633148:TAGG RS06000
gene id: 633148:TAGG_RS06000
uniprot id: D5U2W0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

633148:TAGG RS02275
gene id: 633148:TAGG_RS02275
uniprot id: D5U0S7
names: Similarity
messages: Belongs to the AOR/FOR family.

633148:TAGG RS02730
gene id: 633148:TAGG_RS02730
uniprot id: D5U117
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS04025
gene id: 633148:TAGG_RS04025
uniprot id: D5U1T5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

633148:TAGG RS05810
gene id: 633148:TAGG_RS05810
uniprot id: D5U2S6
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

633148:TAGG RS00980
gene id: 633148:TAGG_RS00980
uniprot id: D5U021
names: Similarity
messages: Belongs to the group II decarboxylase family.

633148:TAGG RS06745
gene id: 633148:TAGG_RS06745
uniprot id: D5U397
names: Similarity
messages: Belongs to the SDO1/SBDS family.

633148:TAGG RS00285
gene id: 633148:TAGG_RS00285
uniprot id: D5TZN6
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS02615
gene id: 633148:TAGG_RS02615
uniprot id: D5U0Z5
names: Similarity
messages: Belongs to the glutamine synthetase family.

633148:TAGG RS02080
gene id: 633148:TAGG_RS02080
uniprot id: D5U0N7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

633148:TAGG RS03900
gene id: 633148:TAGG_RS03900
uniprot id: D5U1Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

633148:TAGG RS00125
gene id: 633148:TAGG_RS00125
uniprot id: D5TZK5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

633148:TAGG RS07090
gene id: 633148:TAGG_RS07090
uniprot id: D5U3G4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

633148:TAGG RS02245
gene id: 633148:TAGG_RS02245
uniprot id: D5U0S1
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS07005
gene id: 633148:TAGG_RS07005
uniprot id: D5U3E8
names: Similarity
messages: Belongs to the MEMO1 family.

633148:TAGG RS04290
gene id: 633148:TAGG_RS04290
uniprot id: D5U1Z0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

633148:TAGG RS00030
gene id: 633148:TAGG_RS00030
uniprot id: D5TZI7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

633148:TAGG RS02045
gene id: 633148:TAGG_RS02045
uniprot id: D5U0N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

633148:TAGG RS00645
gene id: 633148:TAGG_RS00645
uniprot id: D5TZV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

633148:TAGG RS00770
gene id: 633148:TAGG_RS00770
uniprot id: D5TZX9
names: Similarity
messages: Belongs to the TFIIB family.

633148:TAGG RS05650
gene id: 633148:TAGG_RS05650
uniprot id: D5U2P8
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS04675
gene id: 633148:TAGG_RS04675
uniprot id: D5U263
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

633148:TAGG RS06580
gene id: 633148:TAGG_RS06580
uniprot id: D5U367
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

633148:TAGG RS04180
gene id: 633148:TAGG_RS04180
uniprot id: D5U1W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

633148:TAGG RS02390
gene id: 633148:TAGG_RS02390
uniprot id: D5U0V0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

633148:TAGG RS06985
gene id: 633148:TAGG_RS06985
uniprot id: D5U3E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

633148:TAGG RS05070
gene id: 633148:TAGG_RS05070
uniprot id: D5U2D8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

633148:TAGG RS03010
gene id: 633148:TAGG_RS03010
uniprot id: D5U178
names: Similarity
messages: Belongs to the MoaB/Mog family.

633148:TAGG RS03780
gene id: 633148:TAGG_RS03780
uniprot id: D5U1N4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS06255
gene id: 633148:TAGG_RS06255
uniprot id: D5U306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

633148:TAGG RS01420
gene id: 633148:TAGG_RS01420
uniprot id: D5U0A7
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

633148:TAGG RS05830
gene id: 633148:TAGG_RS05830
uniprot id: D5U2T0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

633148:TAGG RS00930
gene id: 633148:TAGG_RS00930
uniprot id: D5U011
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

633148:TAGG RS04680
gene id: 633148:TAGG_RS04680
uniprot id: D5U264
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

633148:TAGG RS07025
gene id: 633148:TAGG_RS07025
uniprot id: D5U3F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

633148:TAGG RS02600
gene id: 633148:TAGG_RS02600
uniprot id: D5U0Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

633148:TAGG RS05335
gene id: 633148:TAGG_RS05335
uniprot id: D5U2I6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

633148:TAGG RS02785
gene id: 633148:TAGG_RS02785
uniprot id: D5U128
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

633148:TAGG RS06510
gene id: 633148:TAGG_RS06510
uniprot id: D5U354
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

633148:TAGG RS05150
gene id: 633148:TAGG_RS05150
uniprot id: D5U2F2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS03935
gene id: 633148:TAGG_RS03935
uniprot id: D5U1R6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

633148:TAGG RS00695
gene id: 633148:TAGG_RS00695
uniprot id: D5TZW4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

633148:TAGG RS01955
gene id: 633148:TAGG_RS01955
uniprot id: D5U0L3
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

633148:TAGG RS06715
gene id: 633148:TAGG_RS06715
uniprot id: D5U391
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

633148:TAGG RS05535
gene id: 633148:TAGG_RS05535
uniprot id: D5U2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

633148:TAGG RS00250
gene id: 633148:TAGG_RS00250
uniprot id: D5TZM9
names: Similarity
messages: Belongs to the eIF-2-alpha family.

633148:TAGG RS04500
gene id: 633148:TAGG_RS04500
uniprot id: D5U230
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

633148:TAGG RS00570
gene id: 633148:TAGG_RS00570
uniprot id: D5TZU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS06325
gene id: 633148:TAGG_RS06325
uniprot id: D5U320
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

633148:TAGG RS06045
gene id: 633148:TAGG_RS06045
uniprot id: D5U2W7
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00090
gene id: 633148:TAGG_RS00090
uniprot id: D5TZJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

633148:TAGG RS03870
gene id: 633148:TAGG_RS03870
uniprot id: D5U1Q3
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

633148:TAGG RS03230
gene id: 633148:TAGG_RS03230
uniprot id: D5U1C3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

633148:TAGG RS04625
gene id: 633148:TAGG_RS04625
uniprot id: D5U253
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

633148:TAGG RS02040
gene id: 633148:TAGG_RS02040
uniprot id: D5U0M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

633148:TAGG RS03125
gene id: 633148:TAGG_RS03125
uniprot id: D5U1A1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS04600
gene id: 633148:TAGG_RS04600
uniprot id: D5U248
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

633148:TAGG RS07065
gene id: 633148:TAGG_RS07065
uniprot id: D5U3F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

633148:TAGG RS05710
gene id: 633148:TAGG_RS05710
uniprot id: D5U2Q8
names: Similarity
messages: Belongs to the UPF0111 family.

633148:TAGG RS02265
gene id: 633148:TAGG_RS02265
uniprot id: D5U0S5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

633148:TAGG RS04650
gene id: 633148:TAGG_RS04650
uniprot id: D5U258
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

633148:TAGG RS07020
gene id: 633148:TAGG_RS07020
uniprot id: D5U3F1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

633148:TAGG RS04015
gene id: 633148:TAGG_RS04015
uniprot id: D5U1T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

633148:TAGG RS01535
gene id: 633148:TAGG_RS01535
uniprot id: D5U0C9
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

633148:TAGG RS03100
gene id: 633148:TAGG_RS03100
uniprot id: D5U196
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

633148:TAGG RS00055
gene id: 633148:TAGG_RS00055
uniprot id: D5TZJ1
names: Similarity
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.

633148:TAGG RS03365
gene id: 633148:TAGG_RS03365
uniprot id: D5U1F0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

633148:TAGG RS02545
gene id: 633148:TAGG_RS02545
uniprot id: D5U0Y1
names: Similarity
messages: Belongs to the UPF0111 family.

633148:TAGG RS02675
gene id: 633148:TAGG_RS02675
uniprot id: D5U106
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

633148:TAGG RS06720
gene id: 633148:TAGG_RS06720
uniprot id: D5U392
names: Function
messages: Probably involved in the biogenesis of the ribosome.

633148:TAGG RS00255
gene id: 633148:TAGG_RS00255
uniprot id: D5TZN0
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

633148:TAGG RS02705
gene id: 633148:TAGG_RS02705
uniprot id: D5U112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

633148:TAGG RS06440
gene id: 633148:TAGG_RS06440
uniprot id: D5U340
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

633148:TAGG RS05350
gene id: 633148:TAGG_RS05350
uniprot id: D5U2I9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

633148:TAGG RS01505
gene id: 633148:TAGG_RS01505
uniprot id: D5U0C3
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

633148:TAGG RS00375
gene id: 633148:TAGG_RS00375
uniprot id: D5TZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

633148:TAGG RS04245
gene id: 633148:TAGG_RS04245
uniprot id: D5U1Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

633148:TAGG RS05895
gene id: 633148:TAGG_RS05895
uniprot id: D5U2U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

633148:TAGG RS02740
gene id: 633148:TAGG_RS02740
uniprot id: D5U119
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS03140
gene id: 633148:TAGG_RS03140
uniprot id: D5U1A4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS04105
gene id: 633148:TAGG_RS04105
uniprot id: D5U1V1
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

633148:TAGG RS03590
gene id: 633148:TAGG_RS03590
uniprot id: D5U1J5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

633148:TAGG RS04100
gene id: 633148:TAGG_RS04100
uniprot id: D5U1V0
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

633148:TAGG RS01695
gene id: 633148:TAGG_RS01695
uniprot id: D5U0G0
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00630
gene id: 633148:TAGG_RS00630
uniprot id: D5TZV2
names: Similarity
messages: Belongs to the MCM family.

633148:TAGG RS07070
gene id: 633148:TAGG_RS07070
uniprot id: D5U3G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS06925
gene id: 633148:TAGG_RS06925
uniprot id: D5U3D2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

633148:TAGG RS03270
gene id: 633148:TAGG_RS03270
uniprot id: D5U1D1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS01785
gene id: 633148:TAGG_RS01785
uniprot id: D5U0H8
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

633148:TAGG RS07120
gene id: 633148:TAGG_RS07120
uniprot id: D5U3G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

633148:TAGG RS06380
gene id: 633148:TAGG_RS06380
uniprot id: D5U329
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

633148:TAGG RS06805
gene id: 633148:TAGG_RS06805
uniprot id: D5U3A8
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

633148:TAGG RS04740
gene id: 633148:TAGG_RS04740
uniprot id: D5U274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

633148:TAGG RS05160
gene id: 633148:TAGG_RS05160
uniprot id: D5U2F4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

633148:TAGG RS00010
gene id: 633148:TAGG_RS00010
uniprot id: D5TZI5
names: Similarity
messages: Belongs to the UPF0215 family.

633148:TAGG RS06750
gene id: 633148:TAGG_RS06750
uniprot id: D5U398
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

633148:TAGG RS03775
gene id: 633148:TAGG_RS03775
uniprot id: D5U1N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

633148:TAGG RS05750
gene id: 633148:TAGG_RS05750
uniprot id: D5U2R5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

633148:TAGG RS02050
gene id: 633148:TAGG_RS02050
uniprot id: D5U0N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS05940
gene id: 633148:TAGG_RS05940
uniprot id: D5U2U8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS02005
gene id: 633148:TAGG_RS02005
uniprot id: D5U0M2
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS01380
gene id: 633148:TAGG_RS01380
uniprot id: D5U099
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

633148:TAGG RS00995
gene id: 633148:TAGG_RS00995
uniprot id: D5U024
names: Caution
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS02985
gene id: 633148:TAGG_RS02985
uniprot id: D5U173
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

633148:TAGG RS05320
gene id: 633148:TAGG_RS05320
uniprot id: D5U2I2
names: Similarity
messages: Belongs to the CutA family.

633148:TAGG RS04210
gene id: 633148:TAGG_RS04210
uniprot id: D5U1X4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

633148:TAGG RS07100
gene id: 633148:TAGG_RS07100
uniprot id: D5U3G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

633148:TAGG RS02700
gene id: 633148:TAGG_RS02700
uniprot id: D5U111
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS06975
gene id: 633148:TAGG_RS06975
uniprot id: D5U3E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

633148:TAGG RS01385
gene id: 633148:TAGG_RS01385
uniprot id: D5U0A0
names: Similarity
messages: Belongs to the ZPR1 family.

633148:TAGG RS00705
gene id: 633148:TAGG_RS00705
uniprot id: D5TZW6
names: Similarity
messages: Belongs to the UPF0201 family.

633148:TAGG RS00015
gene id: 633148:TAGG_RS00015
uniprot id: D5TZI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS06470
gene id: 633148:TAGG_RS06470
uniprot id: D5U346
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS06955
gene id: 633148:TAGG_RS06955
uniprot id: D5U3D8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

633148:TAGG RS06190
gene id: 633148:TAGG_RS06190
uniprot id: D5U2Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

633148:TAGG RS01085
gene id: 633148:TAGG_RS01085
uniprot id: D5U042
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

633148:TAGG RS06550
gene id: 633148:TAGG_RS06550
uniprot id: D5U361
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

633148:TAGG RS00085
gene id: 633148:TAGG_RS00085
uniprot id: D5TZJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

633148:TAGG RS01050
gene id: 633148:TAGG_RS01050
uniprot id: D5U035
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

633148:TAGG RS02575
gene id: 633148:TAGG_RS02575
uniprot id: D5U0Y7
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00320
gene id: 633148:TAGG_RS00320
uniprot id: D5TZP3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

633148:TAGG RS00165
gene id: 633148:TAGG_RS00165
uniprot id: D5TZL3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

633148:TAGG RS01645
gene id: 633148:TAGG_RS01645
uniprot id: D5U0F1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

633148:TAGG RS05530
gene id: 633148:TAGG_RS05530
uniprot id: D5U2M5
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00690
gene id: 633148:TAGG_RS00690
uniprot id: D5TZW3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS05365
gene id: 633148:TAGG_RS05365
uniprot id: D5U2J2
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

633148:TAGG RS02355
gene id: 633148:TAGG_RS02355
uniprot id: D5U0U3
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS01580
gene id: 633148:TAGG_RS01580
uniprot id: D5U0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

633148:TAGG RS01930
gene id: 633148:TAGG_RS01930
uniprot id: D5U0K8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

633148:TAGG RS03855
gene id: 633148:TAGG_RS03855
uniprot id: D5U1P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

633148:TAGG RS04670
gene id: 633148:TAGG_RS04670
uniprot id: D5U262
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

633148:TAGG RS02365
gene id: 633148:TAGG_RS02365
uniprot id: D5U0U5
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

633148:TAGG RS07045
gene id: 633148:TAGG_RS07045
uniprot id: D5U3F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

633148:TAGG RS01290
gene id: 633148:TAGG_RS01290
uniprot id: D5U082
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

633148:TAGG RS02950
gene id: 633148:TAGG_RS02950
uniprot id: D5U166
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

633148:TAGG RS02765
gene id: 633148:TAGG_RS02765
uniprot id: D5U124
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

633148:TAGG RS00315
gene id: 633148:TAGG_RS00315
uniprot id: D5TZP2
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

633148:TAGG RS00550
gene id: 633148:TAGG_RS00550
uniprot id: D5TZT7
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.

633148:TAGG RS04085
gene id: 633148:TAGG_RS04085
uniprot id: D5U1U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

633148:TAGG RS05980
gene id: 633148:TAGG_RS05980
uniprot id: D5U2V6
names: Similarity
messages: Belongs to the UPF0273 family.

633148:TAGG RS04665
gene id: 633148:TAGG_RS04665
uniprot id: D5U261
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

633148:TAGG RS06385
gene id: 633148:TAGG_RS06385
uniprot id: D5U330
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

633148:TAGG RS04295
gene id: 633148:TAGG_RS04295
uniprot id: D5U1Z1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

633148:TAGG RS00755
gene id: 633148:TAGG_RS00755
uniprot id: D5TZX6
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS04955
gene id: 633148:TAGG_RS04955
uniprot id: D5U2B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS06935
gene id: 633148:TAGG_RS06935
uniprot id: D5U3D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

633148:TAGG RS03090
gene id: 633148:TAGG_RS03090
uniprot id: D5U194
names: Similarity
messages: Belongs to the HypE family.

633148:TAGG RS02315
gene id: 633148:TAGG_RS02315
uniprot id: D5U0T5
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS01925
gene id: 633148:TAGG_RS01925
uniprot id: D5U0K7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

633148:TAGG RS02430
gene id: 633148:TAGG_RS02430
uniprot id: D5U0V8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

633148:TAGG RS04230
gene id: 633148:TAGG_RS04230
uniprot id: D5U1X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

633148:TAGG RS03905
gene id: 633148:TAGG_RS03905
uniprot id: D5U1R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

633148:TAGG RS03210
gene id: 633148:TAGG_RS03210
uniprot id: D5U1B9
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS04195
gene id: 633148:TAGG_RS04195
uniprot id: D5U1X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

633148:TAGG RS01295
gene id: 633148:TAGG_RS01295
uniprot id: D5U083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

633148:TAGG RS00200
gene id: 633148:TAGG_RS00200
uniprot id: D5TZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

633148:TAGG RS02060
gene id: 633148:TAGG_RS02060
uniprot id: D5U0N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

633148:TAGG RS03850
gene id: 633148:TAGG_RS03850
uniprot id: D5U1P8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

633148:TAGG RS06895
gene id: 633148:TAGG_RS06895
uniprot id: D5U3C6
names: Similarity
messages: Belongs to the glutaredoxin family.

633148:TAGG RS05230
gene id: 633148:TAGG_RS05230
uniprot id: D5U2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

633148:TAGG RS06910
gene id: 633148:TAGG_RS06910
uniprot id: D5U3C9
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

633148:TAGG RS04615
gene id: 633148:TAGG_RS04615
uniprot id: D5U251
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS03040
gene id: 633148:TAGG_RS03040
uniprot id: D5U184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

633148:TAGG RS00120
gene id: 633148:TAGG_RS00120
uniprot id: D5TZK4
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS00225
gene id: 633148:TAGG_RS00225
uniprot id: D5TZM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

633148:TAGG RS04320
gene id: 633148:TAGG_RS04320
uniprot id: D5U1Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

633148:TAGG RS01455
gene id: 633148:TAGG_RS01455
uniprot id: D5U0B4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

633148:TAGG RS04235
gene id: 633148:TAGG_RS04235
uniprot id: D5U1X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS00565
gene id: 633148:TAGG_RS00565
uniprot id: D5TZU0
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS03485
gene id: 633148:TAGG_RS03485
uniprot id: D5U1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

633148:TAGG RS03320
gene id: 633148:TAGG_RS03320
uniprot id: D5U1E1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

633148:TAGG RS07110
gene id: 633148:TAGG_RS07110
uniprot id: D5U3G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

633148:TAGG RS03595
gene id: 633148:TAGG_RS03595
uniprot id: D5U1J6
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

633148:TAGG RS04575
gene id: 633148:TAGG_RS04575
uniprot id: D5U243
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

633148:TAGG RS04605
gene id: 633148:TAGG_RS04605
uniprot id: D5U249
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

633148:TAGG RS07060
gene id: 633148:TAGG_RS07060
uniprot id: D5U3F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

633148:TAGG RS02105
gene id: 633148:TAGG_RS02105
uniprot id: D5U0P3
names: Subcellular Location Annotation
messages: Membrane

633148:TAGG RS04815
gene id: 633148:TAGG_RS04815
uniprot id: D5U289
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

633148:TAGG RS05975
gene id: 633148:TAGG_RS05975
uniprot id: D5U2V5
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

633148:TAGG RS03955
gene id: 633148:TAGG_RS03955
uniprot id: D5U1S0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

633148:TAGG RS06165
gene id: 633148:TAGG_RS06165
uniprot id: D5U2Z1
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

633148:TAGG RS00345
gene id: 633148:TAGG_RS00345
uniprot id: D5TZP7
names: Similarity
messages: Belongs to the PGI/PMI family.

633148:TAGG RS05485
gene id: 633148:TAGG_RS05485
uniprot id: D5U2L6
names: Similarity
messages: Belongs to the UPF0235 family.

633148:TAGG RS01750
gene id: 633148:TAGG_RS01750
uniprot id: D5U0H1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.