632292:CALHY RS13250
gene id: 632292:CALHY_RS13250
uniprot id: E4QB06
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

632292:CALHY RS09275
gene id: 632292:CALHY_RS09275
uniprot id: E4QD51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS11235
gene id: 632292:CALHY_RS11235
uniprot id: E4Q879
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

632292:CALHY RS00395
gene id: 632292:CALHY_RS00395
uniprot id: E4Q9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS10855
gene id: 632292:CALHY_RS10855
uniprot id: E4Q7T3
names: Similarity
messages: Belongs to the P(II) protein family.

632292:CALHY RS06605
gene id: 632292:CALHY_RS06605
uniprot id: E4QA45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

632292:CALHY RS12535
gene id: 632292:CALHY_RS12535
uniprot id: E4Q9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

632292:CALHY RS06925
gene id: 632292:CALHY_RS06925
uniprot id: E4QAA8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

632292:CALHY RS08605
gene id: 632292:CALHY_RS08605
uniprot id: E4QCJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

632292:CALHY RS09430
gene id: 632292:CALHY_RS09430
uniprot id: E4QDF8
names: Similarity
messages: Belongs to the AOR/FOR family.

632292:CALHY RS10475
gene id: 632292:CALHY_RS10475
uniprot id: E4Q7D4
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS09585
gene id: 632292:CALHY_RS09585
uniprot id: E4QDI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

632292:CALHY RS10175
gene id: 632292:CALHY_RS10175
uniprot id: E4QE99
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

632292:CALHY RS03320
gene id: 632292:CALHY_RS03320
uniprot id: E4QD98
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS10085
gene id: 632292:CALHY_RS10085
uniprot id: E4QE08
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

632292:CALHY RS09065
gene id: 632292:CALHY_RS09065
uniprot id: E4QD12
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS13145
gene id: 632292:CALHY_RS13145
uniprot id: E4QAI8
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS03685
gene id: 632292:CALHY_RS03685
uniprot id: E4QDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS11455
gene id: 632292:CALHY_RS11455
uniprot id: E4Q8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

632292:CALHY RS00630
gene id: 632292:CALHY_RS00630
uniprot id: E4QA13
names: Similarity
messages: Belongs to the FGGY kinase family.

632292:CALHY RS12385
gene id: 632292:CALHY_RS12385
uniprot id: E4Q992
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS12360
gene id: 632292:CALHY_RS12360
uniprot id: E4Q987
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

632292:CALHY RS09755
gene id: 632292:CALHY_RS09755
uniprot id: E4QDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

632292:CALHY RS09610
gene id: 632292:CALHY_RS09610
uniprot id: E4QDJ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632292:CALHY RS12240
gene id: 632292:CALHY_RS12240
uniprot id: E4Q963
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

632292:CALHY RS06560
gene id: 632292:CALHY_RS06560
uniprot id: E4Q9N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

632292:CALHY RS10840
gene id: 632292:CALHY_RS10840
uniprot id: E4Q7K3
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

632292:CALHY RS03510
gene id: 632292:CALHY_RS03510
uniprot id: E4QDL1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

632292:CALHY RS11380
gene id: 632292:CALHY_RS11380
uniprot id: E4Q8A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS02940
gene id: 632292:CALHY_RS02940
uniprot id: E4QCU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

632292:CALHY RS04895
gene id: 632292:CALHY_RS04895
uniprot id: E4Q7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

632292:CALHY RS11465
gene id: 632292:CALHY_RS11465
uniprot id: E4Q8B8
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08475
gene id: 632292:CALHY_RS08475
uniprot id: E4QC97
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

632292:CALHY RS04775
gene id: 632292:CALHY_RS04775
uniprot id: E4Q7N7
names: Similarity
messages: Belongs to the peptidase S41A family.

632292:CALHY RS02570
gene id: 632292:CALHY_RS02570
uniprot id: E4QCF4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

632292:CALHY RS12930
gene id: 632292:CALHY_RS12930
uniprot id: E4QAE3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

632292:CALHY RS05450
gene id: 632292:CALHY_RS05450
uniprot id: E4Q8F8
names: Similarity
messages: Belongs to the bacterial flagellin family.

632292:CALHY RS02640
gene id: 632292:CALHY_RS02640
uniprot id: E4QCG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632292:CALHY RS05445
gene id: 632292:CALHY_RS05445
uniprot id: E4Q8F7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

632292:CALHY RS01945
gene id: 632292:CALHY_RS01945
uniprot id: E4QBV6
names: Similarity
messages: Belongs to the GSP E family.

632292:CALHY RS08955
gene id: 632292:CALHY_RS08955
uniprot id: E4QCY9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

632292:CALHY RS08910
gene id: 632292:CALHY_RS08910
uniprot id: E4QCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

632292:CALHY RS08135
gene id: 632292:CALHY_RS08135
uniprot id: E4QC29
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632292:CALHY RS10900
gene id: 632292:CALHY_RS10900
uniprot id: E4Q7U2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

632292:CALHY RS06610
gene id: 632292:CALHY_RS06610
uniprot id: E4QA46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

632292:CALHY RS11550
gene id: 632292:CALHY_RS11550
uniprot id: E4Q8D6
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

632292:CALHY RS03570
gene id: 632292:CALHY_RS03570
uniprot id: E4QDM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

632292:CALHY RS02970
gene id: 632292:CALHY_RS02970
uniprot id: E4QCV4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

632292:CALHY RS09770
gene id: 632292:CALHY_RS09770
uniprot id: E4QDV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

632292:CALHY RS05745
gene id: 632292:CALHY_RS05745
uniprot id: E4Q8L3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

632292:CALHY RS11065
gene id: 632292:CALHY_RS11065
uniprot id: E4Q7X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS01260
gene id: 632292:CALHY_RS01260
uniprot id: E4QB22
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

632292:CALHY RS04195
gene id: 632292:CALHY_RS04195
uniprot id: E4QE71
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

632292:CALHY RS06005
gene id: 632292:CALHY_RS06005
uniprot id: E4Q8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

632292:CALHY RS04690
gene id: 632292:CALHY_RS04690
uniprot id: E4Q7M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

632292:CALHY RS00350
gene id: 632292:CALHY_RS00350
uniprot id: E4Q9G1
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

632292:CALHY RS04085
gene id: 632292:CALHY_RS04085
uniprot id: E4QE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

632292:CALHY RS10090
gene id: 632292:CALHY_RS10090
uniprot id: E4QE09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS10240
gene id: 632292:CALHY_RS10240
uniprot id: E4QEB2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS05590
gene id: 632292:CALHY_RS05590
uniprot id: E4Q8I2
names: Subcellular Location Annotation
messages: Cell membrane

632292:CALHY RS12655
gene id: 632292:CALHY_RS12655
uniprot id: E4Q9T9
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

632292:CALHY RS09005
gene id: 632292:CALHY_RS09005
uniprot id: E4QD00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

632292:CALHY RS10935
gene id: 632292:CALHY_RS10935
uniprot id: E4Q7U9
names: Similarity
messages: Belongs to the class-I fumarase family.

632292:CALHY RS08620
gene id: 632292:CALHY_RS08620
uniprot id: E4QCK1
names: Similarity
messages: Belongs to the YicC/YloC family.

632292:CALHY RS10570
gene id: 632292:CALHY_RS10570
uniprot id: E4Q7F1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

632292:CALHY RS05165
gene id: 632292:CALHY_RS05165
uniprot id: E4Q838
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

632292:CALHY RS09245
gene id: 632292:CALHY_RS09245
uniprot id: E4QD45
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

632292:CALHY RS03060
gene id: 632292:CALHY_RS03060
uniprot id: E4QCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

632292:CALHY RS06540
gene id: 632292:CALHY_RS06540
uniprot id: E4Q9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

632292:CALHY RS05100
gene id: 632292:CALHY_RS05100
uniprot id: E4Q825
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

632292:CALHY RS05055
gene id: 632292:CALHY_RS05055
uniprot id: E4Q816
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

632292:CALHY RS06255
gene id: 632292:CALHY_RS06255
uniprot id: E4Q9H8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

632292:CALHY RS06760
gene id: 632292:CALHY_RS06760
uniprot id: E4QA77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Monomer.

632292:CALHY RS00330
gene id: 632292:CALHY_RS00330
uniprot id: E4Q9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS01140
gene id: 632292:CALHY_RS01140
uniprot id: E4QAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

632292:CALHY RS04810
gene id: 632292:CALHY_RS04810
uniprot id: E4Q7P4
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

632292:CALHY RS11625
gene id: 632292:CALHY_RS11625
uniprot id: E4Q8M3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS06350
gene id: 632292:CALHY_RS06350
uniprot id: E4Q9J7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

632292:CALHY RS06225
gene id: 632292:CALHY_RS06225
uniprot id: E4Q9H3
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS05350
gene id: 632292:CALHY_RS05350
uniprot id: E4Q869
names: Similarity
messages: Belongs to the TrpC family.

632292:CALHY RS06135
gene id: 632292:CALHY_RS06135
uniprot id: E4Q912
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS02785
gene id: 632292:CALHY_RS02785
uniprot id: E4QCS2
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS12425
gene id: 632292:CALHY_RS12425
uniprot id: E4Q9P4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS03270
gene id: 632292:CALHY_RS03270
uniprot id: E4QD88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

632292:CALHY RS11945
gene id: 632292:CALHY_RS11945
uniprot id: E4Q8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

632292:CALHY RS13245
gene id: 632292:CALHY_RS13245
uniprot id: E4QB05
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

632292:CALHY RS02415
gene id: 632292:CALHY_RS02415
uniprot id: E4QCC3
names: Similarity
messages: Belongs to the UPF0251 family.

632292:CALHY RS08345
gene id: 632292:CALHY_RS08345
uniprot id: E4QC71
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

632292:CALHY RS01020
gene id: 632292:CALHY_RS01020
uniprot id: E4QAN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS09125
gene id: 632292:CALHY_RS09125
uniprot id: E4QD23
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS03295
gene id: 632292:CALHY_RS03295
uniprot id: E4QD93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

632292:CALHY RS05890
gene id: 632292:CALHY_RS05890
uniprot id: E4Q8W8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632292:CALHY RS04850
gene id: 632292:CALHY_RS04850
uniprot id: E4Q7Q2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

632292:CALHY RS04215
gene id: 632292:CALHY_RS04215
uniprot id: E4QE75
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

632292:CALHY RS02820
gene id: 632292:CALHY_RS02820
uniprot id: E4QCS8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

632292:CALHY RS10200
gene id: 632292:CALHY_RS10200
uniprot id: E4QEA4
names: Similarity
messages: Belongs to the glutamine synthetase family.

632292:CALHY RS07705
gene id: 632292:CALHY_RS07705
uniprot id: E4QBE3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

632292:CALHY RS13220
gene id: 632292:CALHY_RS13220
uniprot id: E4QB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

632292:CALHY RS11470
gene id: 632292:CALHY_RS11470
uniprot id: E4Q8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

632292:CALHY RS07370
gene id: 632292:CALHY_RS07370
uniprot id: E4QB76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

632292:CALHY RS08510
gene id: 632292:CALHY_RS08510
uniprot id: E4QCA4
names: Similarity
messages: Belongs to the ribF family.

632292:CALHY RS03065
gene id: 632292:CALHY_RS03065
uniprot id: E4QCX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

632292:CALHY RS05700
gene id: 632292:CALHY_RS05700
uniprot id: E4Q8K3
names: Similarity
messages: Belongs to the thioredoxin family.

632292:CALHY RS09390
gene id: 632292:CALHY_RS09390
uniprot id: E4QDF0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

632292:CALHY RS11190
gene id: 632292:CALHY_RS11190
uniprot id: E4Q800
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

632292:CALHY RS07885
gene id: 632292:CALHY_RS07885
uniprot id: E4QBQ4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

632292:CALHY RS09260
gene id: 632292:CALHY_RS09260
uniprot id: E4QD48
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS13130
gene id: 632292:CALHY_RS13130
uniprot id: E4QAI4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632292:CALHY RS08430
gene id: 632292:CALHY_RS08430
uniprot id: E4QC88
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

632292:CALHY RS04815
gene id: 632292:CALHY_RS04815
uniprot id: E4Q7P5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

632292:CALHY RS03155
gene id: 632292:CALHY_RS03155
uniprot id: E4QD65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

632292:CALHY RS10250
gene id: 632292:CALHY_RS10250
uniprot id: E4QEB4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

632292:CALHY RS05485
gene id: 632292:CALHY_RS05485
uniprot id: E4Q8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

632292:CALHY RS04370
gene id: 632292:CALHY_RS04370
uniprot id: E4Q783
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

632292:CALHY RS00575
gene id: 632292:CALHY_RS00575
uniprot id: E4QA02
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS04365
gene id: 632292:CALHY_RS04365
uniprot id: E4Q782
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

632292:CALHY RS04380
gene id: 632292:CALHY_RS04380
uniprot id: E4Q785
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS02255
gene id: 632292:CALHY_RS02255
uniprot id: E4QC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

632292:CALHY RS03180
gene id: 632292:CALHY_RS03180
uniprot id: E4QD70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS06170
gene id: 632292:CALHY_RS06170
uniprot id: E4Q919
names: Similarity
messages: Belongs to the peptidase S16 family.

632292:CALHY RS00450
gene id: 632292:CALHY_RS00450
uniprot id: E4Q9X7
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08850
gene id: 632292:CALHY_RS08850
uniprot id: E4QCP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

632292:CALHY RS08515
gene id: 632292:CALHY_RS08515
uniprot id: E4QCA5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

632292:CALHY RS00360
gene id: 632292:CALHY_RS00360
uniprot id: E4Q9G3
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

632292:CALHY RS07975
gene id: 632292:CALHY_RS07975
uniprot id: E4QBS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

632292:CALHY RS09865
gene id: 632292:CALHY_RS09865
uniprot id: E4QDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

632292:CALHY RS08215
gene id: 632292:CALHY_RS08215
uniprot id: E4QC45
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

632292:CALHY RS04755
gene id: 632292:CALHY_RS04755
uniprot id: E4Q7N3
names: Similarity
messages: Belongs to the CdaR family.

632292:CALHY RS05190
gene id: 632292:CALHY_RS05190
uniprot id: E4Q843
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

632292:CALHY RS10355
gene id: 632292:CALHY_RS10355
uniprot id: E4QED6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

632292:CALHY RS00495
gene id: 632292:CALHY_RS00495
uniprot id: E4Q9Y6
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632292:CALHY RS04425
gene id: 632292:CALHY_RS04425
uniprot id: E4Q794
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

632292:CALHY RS08930
gene id: 632292:CALHY_RS08930
uniprot id: E4QCY4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

632292:CALHY RS11340
gene id: 632292:CALHY_RS11340
uniprot id: E4Q8A0
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

632292:CALHY RS08070
gene id: 632292:CALHY_RS08070
uniprot id: E4QBU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

632292:CALHY RS00550
gene id: 632292:CALHY_RS00550
uniprot id: E4Q9Z7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS13610
gene id: 632292:CALHY_RS13610
uniprot id: E4QB02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

632292:CALHY RS09060
gene id: 632292:CALHY_RS09060
uniprot id: E4QD11
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS05185
gene id: 632292:CALHY_RS05185
uniprot id: E4Q842
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

632292:CALHY RS04525
gene id: 632292:CALHY_RS04525
uniprot id: E4Q7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS04375
gene id: 632292:CALHY_RS04375
uniprot id: E4Q784
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS06750
gene id: 632292:CALHY_RS06750
uniprot id: E4QA75
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

632292:CALHY RS00420
gene id: 632292:CALHY_RS00420
uniprot id: E4Q9X1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632292:CALHY RS05045
gene id: 632292:CALHY_RS05045
uniprot id: E4Q814
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

632292:CALHY RS08130
gene id: 632292:CALHY_RS08130
uniprot id: E4QBV4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

632292:CALHY RS10010
gene id: 632292:CALHY_RS10010
uniprot id: E4QDZ4
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS06895
gene id: 632292:CALHY_RS06895
uniprot id: E4QAA2
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

632292:CALHY RS02815
gene id: 632292:CALHY_RS02815
uniprot id: E4QCS7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

632292:CALHY RS07515
gene id: 632292:CALHY_RS07515
uniprot id: E4QBA5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

632292:CALHY RS05620
gene id: 632292:CALHY_RS05620
uniprot id: E4Q8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS04870
gene id: 632292:CALHY_RS04870
uniprot id: E4Q7Q6
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS06180
gene id: 632292:CALHY_RS06180
uniprot id: E4Q921
names: Similarity
messages: Belongs to the UPF0047 family.

632292:CALHY RS05375
gene id: 632292:CALHY_RS05375
uniprot id: E4Q874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

632292:CALHY RS00535
gene id: 632292:CALHY_RS00535
uniprot id: E4Q9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

632292:CALHY RS04605
gene id: 632292:CALHY_RS04605
uniprot id: E4Q7D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

632292:CALHY RS00010
gene id: 632292:CALHY_RS00010
uniprot id: E4Q8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

632292:CALHY RS09690
gene id: 632292:CALHY_RS09690
uniprot id: E4QDT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

632292:CALHY RS12325
gene id: 632292:CALHY_RS12325
uniprot id: E4Q980
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS06330
gene id: 632292:CALHY_RS06330
uniprot id: E4Q9J3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

632292:CALHY RS08355
gene id: 632292:CALHY_RS08355
uniprot id: E4QC73
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

632292:CALHY RS10675
gene id: 632292:CALHY_RS10675
uniprot id: E4Q7H1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632292:CALHY RS10460
gene id: 632292:CALHY_RS10460
uniprot id: E4QEF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

632292:CALHY RS06515
gene id: 632292:CALHY_RS06515
uniprot id: E4Q9M8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS10810
gene id: 632292:CALHY_RS10810
uniprot id: E4Q7J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS10645
gene id: 632292:CALHY_RS10645
uniprot id: E4Q7G5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632292:CALHY RS09600
gene id: 632292:CALHY_RS09600
uniprot id: E4QDJ2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

632292:CALHY RS08755
gene id: 632292:CALHY_RS08755
uniprot id: E4QCM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

632292:CALHY RS04410
gene id: 632292:CALHY_RS04410
uniprot id: E4Q790
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632292:CALHY RS05000
gene id: 632292:CALHY_RS05000
uniprot id: E4Q7T0
names: Similarity
messages: Belongs to the peptidase M18 family.

632292:CALHY RS05305
gene id: 632292:CALHY_RS05305
uniprot id: E4Q860
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

632292:CALHY RS08365
gene id: 632292:CALHY_RS08365
uniprot id: E4QC75
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

632292:CALHY RS09485
gene id: 632292:CALHY_RS09485
uniprot id: E4QDG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

632292:CALHY RS09630
gene id: 632292:CALHY_RS09630
uniprot id: E4QDJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

632292:CALHY RS03585
gene id: 632292:CALHY_RS03585
uniprot id: E4QDM6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

632292:CALHY RS09145
gene id: 632292:CALHY_RS09145
uniprot id: E4QD27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

632292:CALHY RS04325
gene id: 632292:CALHY_RS04325
uniprot id: E4Q774
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

632292:CALHY RS11765
gene id: 632292:CALHY_RS11765
uniprot id: E4Q8P9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

632292:CALHY RS03285
gene id: 632292:CALHY_RS03285
uniprot id: E4QD91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

632292:CALHY RS12090
gene id: 632292:CALHY_RS12090
uniprot id: E4Q934
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Monomer.

632292:CALHY RS06300
gene id: 632292:CALHY_RS06300
uniprot id: E4Q9I7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632292:CALHY RS11250
gene id: 632292:CALHY_RS11250
uniprot id: E4Q882
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

632292:CALHY RS04650
gene id: 632292:CALHY_RS04650
uniprot id: E4Q7L2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

632292:CALHY RS03260
gene id: 632292:CALHY_RS03260
uniprot id: E4QD86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS11225
gene id: 632292:CALHY_RS11225
uniprot id: E4Q806
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

632292:CALHY RS06765
gene id: 632292:CALHY_RS06765
uniprot id: E4QA78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

632292:CALHY RS10980
gene id: 632292:CALHY_RS10980
uniprot id: E4Q7V9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

632292:CALHY RS04745
gene id: 632292:CALHY_RS04745
uniprot id: E4Q7N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

632292:CALHY RS08025
gene id: 632292:CALHY_RS08025
uniprot id: E4QBT3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

632292:CALHY RS01655
gene id: 632292:CALHY_RS01655
uniprot id: E4QBG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

632292:CALHY RS07160
gene id: 632292:CALHY_RS07160
uniprot id: E4QAV0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

632292:CALHY RS00280
gene id: 632292:CALHY_RS00280
uniprot id: E4Q9E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS00565
gene id: 632292:CALHY_RS00565
uniprot id: E4QA00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

632292:CALHY RS00485
gene id: 632292:CALHY_RS00485
uniprot id: E4Q9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS02995
gene id: 632292:CALHY_RS02995
uniprot id: E4QCV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS07985
gene id: 632292:CALHY_RS07985
uniprot id: E4QBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

632292:CALHY RS06510
gene id: 632292:CALHY_RS06510
uniprot id: E4Q9M7
names: Similarity
messages: Belongs to the HypE family.

632292:CALHY RS00250
gene id: 632292:CALHY_RS00250
uniprot id: E4Q9E1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS12305
gene id: 632292:CALHY_RS12305
uniprot id: E4Q976
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

632292:CALHY RS07795
gene id: 632292:CALHY_RS07795
uniprot id: E4QBN6
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

632292:CALHY RS09730
gene id: 632292:CALHY_RS09730
uniprot id: E4QDU5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

632292:CALHY RS10510
gene id: 632292:CALHY_RS10510
uniprot id: E4Q7E0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

632292:CALHY RS09520
gene id: 632292:CALHY_RS09520
uniprot id: E4QDH6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

632292:CALHY RS02610
gene id: 632292:CALHY_RS02610
uniprot id: E4QCG1
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS05595
gene id: 632292:CALHY_RS05595
uniprot id: E4Q8I3
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

632292:CALHY RS09500
gene id: 632292:CALHY_RS09500
uniprot id: E4QDH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

632292:CALHY RS12430
gene id: 632292:CALHY_RS12430
uniprot id: E4Q9P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

632292:CALHY RS03485
gene id: 632292:CALHY_RS03485
uniprot id: E4QDC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

632292:CALHY RS05240
gene id: 632292:CALHY_RS05240
uniprot id: E4Q851
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

632292:CALHY RS06295
gene id: 632292:CALHY_RS06295
uniprot id: E4Q9I6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

632292:CALHY RS08595
gene id: 632292:CALHY_RS08595
uniprot id: E4QCJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

632292:CALHY RS05090
gene id: 632292:CALHY_RS05090
uniprot id: E4Q823
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

632292:CALHY RS08775
gene id: 632292:CALHY_RS08775
uniprot id: E4QCN0
names: Similarity
messages: Belongs to the asp23 family.

632292:CALHY RS02890
gene id: 632292:CALHY_RS02890
uniprot id: E4QCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS11155
gene id: 632292:CALHY_RS11155
uniprot id: E4Q7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

632292:CALHY RS07585
gene id: 632292:CALHY_RS07585
uniprot id: E4QBB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS04440
gene id: 632292:CALHY_RS04440
uniprot id: E4Q797
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

632292:CALHY RS03250
gene id: 632292:CALHY_RS03250
uniprot id: E4QD84
names: Similarity
messages: Belongs to the UPF0237 family.

632292:CALHY RS00020
gene id: 632292:CALHY_RS00020
uniprot id: E4Q999
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

632292:CALHY RS07715
gene id: 632292:CALHY_RS07715
uniprot id: E4QBE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

632292:CALHY RS00645
gene id: 632292:CALHY_RS00645
uniprot id: E4QA16
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

632292:CALHY RS04910
gene id: 632292:CALHY_RS04910
uniprot id: E4Q7R4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS00065
gene id: 632292:CALHY_RS00065
uniprot id: E4Q9A7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

632292:CALHY RS05130
gene id: 632292:CALHY_RS05130
uniprot id: E4Q831
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

632292:CALHY RS10680
gene id: 632292:CALHY_RS10680
uniprot id: E4Q7H2
names: Similarity
messages: Belongs to the UPF0145 family.

632292:CALHY RS07440
gene id: 632292:CALHY_RS07440
uniprot id: E4QB90
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

632292:CALHY RS08545
gene id: 632292:CALHY_RS08545
uniprot id: E4QCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

632292:CALHY RS10965
gene id: 632292:CALHY_RS10965
uniprot id: E4Q7V6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS02285
gene id: 632292:CALHY_RS02285
uniprot id: E4QC21
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632292:CALHY RS09310
gene id: 632292:CALHY_RS09310
uniprot id: E4QDD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632292:CALHY RS02925
gene id: 632292:CALHY_RS02925
uniprot id: E4QCU5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

632292:CALHY RS08395
gene id: 632292:CALHY_RS08395
uniprot id: E4QC81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

632292:CALHY RS09910
gene id: 632292:CALHY_RS09910
uniprot id: E4QDX4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.
messages: Belongs to the CapA family.

632292:CALHY RS05530
gene id: 632292:CALHY_RS05530
uniprot id: E4Q8H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

632292:CALHY RS08425
gene id: 632292:CALHY_RS08425
uniprot id: E4QC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

632292:CALHY RS02650
gene id: 632292:CALHY_RS02650
uniprot id: E4QCG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

632292:CALHY RS09935
gene id: 632292:CALHY_RS09935
uniprot id: E4QDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

632292:CALHY RS10605
gene id: 632292:CALHY_RS10605
uniprot id: E4Q7F7
names: Similarity
messages: Belongs to the UPF0758 family.

632292:CALHY RS10075
gene id: 632292:CALHY_RS10075
uniprot id: E4QE06
names: Similarity
messages: Belongs to the UPF0047 family.

632292:CALHY RS11565
gene id: 632292:CALHY_RS11565
uniprot id: E4Q8D8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632292:CALHY RS07405
gene id: 632292:CALHY_RS07405
uniprot id: E4QB83
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

632292:CALHY RS10380
gene id: 632292:CALHY_RS10380
uniprot id: E4QEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS06825
gene id: 632292:CALHY_RS06825
uniprot id: E4QA88
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08055
gene id: 632292:CALHY_RS08055
uniprot id: E4QBU0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

632292:CALHY RS06040
gene id: 632292:CALHY_RS06040
uniprot id: E4Q8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

632292:CALHY RS04355
gene id: 632292:CALHY_RS04355
uniprot id: E4Q780
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS02510
gene id: 632292:CALHY_RS02510
uniprot id: E4QCE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12140
gene id: 632292:CALHY_RS12140
uniprot id: E4Q944
names: Similarity
messages: Belongs to the HepT RNase toxin family.

632292:CALHY RS11180
gene id: 632292:CALHY_RS11180
uniprot id: E4Q7Z8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

632292:CALHY RS04070
gene id: 632292:CALHY_RS04070
uniprot id: E4QE48
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

632292:CALHY RS05470
gene id: 632292:CALHY_RS05470
uniprot id: E4Q8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

632292:CALHY RS07815
gene id: 632292:CALHY_RS07815
uniprot id: E4QBP0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

632292:CALHY RS11855
gene id: 632292:CALHY_RS11855
uniprot id: E4Q8R3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

632292:CALHY RS08010
gene id: 632292:CALHY_RS08010
uniprot id: E4QBT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

632292:CALHY RS00510
gene id: 632292:CALHY_RS00510
uniprot id: E4Q9Y9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS10585
gene id: 632292:CALHY_RS10585
uniprot id: E4Q7F3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632292:CALHY RS02975
gene id: 632292:CALHY_RS02975
uniprot id: E4QCV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

632292:CALHY RS06430
gene id: 632292:CALHY_RS06430
uniprot id: E4Q9L2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

632292:CALHY RS12375
gene id: 632292:CALHY_RS12375
uniprot id: E4Q990
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12650
gene id: 632292:CALHY_RS12650
uniprot id: E4Q9T8
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

632292:CALHY RS08610
gene id: 632292:CALHY_RS08610
uniprot id: E4QCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

632292:CALHY RS11490
gene id: 632292:CALHY_RS11490
uniprot id: E4Q8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS06535
gene id: 632292:CALHY_RS06535
uniprot id: E4Q9N2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

632292:CALHY RS07635
gene id: 632292:CALHY_RS07635
uniprot id: E4QBC9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

632292:CALHY RS10975
gene id: 632292:CALHY_RS10975
uniprot id: E4Q7V8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

632292:CALHY RS09490
gene id: 632292:CALHY_RS09490
uniprot id: E4QDH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

632292:CALHY RS02760
gene id: 632292:CALHY_RS02760
uniprot id: E4QCR7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

632292:CALHY RS10215
gene id: 632292:CALHY_RS10215
uniprot id: E4QEA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

632292:CALHY RS06565
gene id: 632292:CALHY_RS06565
uniprot id: E4Q9N8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS05725
gene id: 632292:CALHY_RS05725
uniprot id: E4Q8K9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

632292:CALHY RS02275
gene id: 632292:CALHY_RS02275
uniprot id: E4QC20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS13210
gene id: 632292:CALHY_RS13210
uniprot id: E4QAZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS03085
gene id: 632292:CALHY_RS03085
uniprot id: E4QCX7
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

632292:CALHY RS10970
gene id: 632292:CALHY_RS10970
uniprot id: E4Q7V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

632292:CALHY RS10020
gene id: 632292:CALHY_RS10020
uniprot id: E4QDZ6
names: Similarity
messages: Belongs to the UPF0342 family.

632292:CALHY RS06900
gene id: 632292:CALHY_RS06900
uniprot id: E4QAA3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

632292:CALHY RS05975
gene id: 632292:CALHY_RS05975
uniprot id: E4Q8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

632292:CALHY RS02315
gene id: 632292:CALHY_RS02315
uniprot id: E4QC27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

632292:CALHY RS09330
gene id: 632292:CALHY_RS09330
uniprot id: E4QDD8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

632292:CALHY RS05025
gene id: 632292:CALHY_RS05025
uniprot id: E4Q809
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS05280
gene id: 632292:CALHY_RS05280
uniprot id: E4Q855
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS06660
gene id: 632292:CALHY_RS06660
uniprot id: E4QA57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

632292:CALHY RS01455
gene id: 632292:CALHY_RS01455
uniprot id: E4QB57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS08260
gene id: 632292:CALHY_RS08260
uniprot id: E4QC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS08225
gene id: 632292:CALHY_RS08225
uniprot id: E4QC47
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

632292:CALHY RS06735
gene id: 632292:CALHY_RS06735
uniprot id: E4QA72
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

632292:CALHY RS09215
gene id: 632292:CALHY_RS09215
uniprot id: E4QD39
names: Similarity
messages: Belongs to the NadC/ModD family.

632292:CALHY RS05150
gene id: 632292:CALHY_RS05150
uniprot id: E4Q835
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

632292:CALHY RS05135
gene id: 632292:CALHY_RS05135
uniprot id: E4Q832
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

632292:CALHY RS12620
gene id: 632292:CALHY_RS12620
uniprot id: E4Q9T2
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

632292:CALHY RS05795
gene id: 632292:CALHY_RS05795
uniprot id: E4Q8U9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

632292:CALHY RS10925
gene id: 632292:CALHY_RS10925
uniprot id: E4Q7U7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

632292:CALHY RS08410
gene id: 632292:CALHY_RS08410
uniprot id: E4QC84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

632292:CALHY RS07970
gene id: 632292:CALHY_RS07970
uniprot id: E4QBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

632292:CALHY RS03325
gene id: 632292:CALHY_RS03325
uniprot id: E4QD99
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS11130
gene id: 632292:CALHY_RS11130
uniprot id: E4Q7Y8
names: Similarity
messages: Belongs to the DapA family.

632292:CALHY RS03040
gene id: 632292:CALHY_RS03040
uniprot id: E4QCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

632292:CALHY RS05315
gene id: 632292:CALHY_RS05315
uniprot id: E4Q862
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632292:CALHY RS10440
gene id: 632292:CALHY_RS10440
uniprot id: E4QEF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS03080
gene id: 632292:CALHY_RS03080
uniprot id: E4QCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

632292:CALHY RS07225
gene id: 632292:CALHY_RS07225
uniprot id: E4QAW3
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

632292:CALHY RS09625
gene id: 632292:CALHY_RS09625
uniprot id: E4QDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

632292:CALHY RS03525
gene id: 632292:CALHY_RS03525
uniprot id: E4QDL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS12345
gene id: 632292:CALHY_RS12345
uniprot id: E4Q984
names: Similarity
messages: Belongs to the RutC family.

632292:CALHY RS06045
gene id: 632292:CALHY_RS06045
uniprot id: E4Q8Z7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS06065
gene id: 632292:CALHY_RS06065
uniprot id: E4Q900
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

632292:CALHY RS07490
gene id: 632292:CALHY_RS07490
uniprot id: E4QBA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS06730
gene id: 632292:CALHY_RS06730
uniprot id: E4QA71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

632292:CALHY RS03580
gene id: 632292:CALHY_RS03580
uniprot id: E4QDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

632292:CALHY RS07485
gene id: 632292:CALHY_RS07485
uniprot id: E4QB99
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

632292:CALHY RS00880
gene id: 632292:CALHY_RS00880
uniprot id: E4QAK7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS01435
gene id: 632292:CALHY_RS01435
uniprot id: E4QB53
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

632292:CALHY RS08200
gene id: 632292:CALHY_RS08200
uniprot id: E4QC42
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

632292:CALHY RS06140
gene id: 632292:CALHY_RS06140
uniprot id: E4Q913
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS10860
gene id: 632292:CALHY_RS10860
uniprot id: E4Q7T4
names: Similarity
messages: Belongs to the P(II) protein family.

632292:CALHY RS10300
gene id: 632292:CALHY_RS10300
uniprot id: E4QEC4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

632292:CALHY RS01695
gene id: 632292:CALHY_RS01695
uniprot id: E4QBH6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

632292:CALHY RS09470
gene id: 632292:CALHY_RS09470
uniprot id: E4QDG6
names: Similarity
messages: Belongs to the IMPACT family.

632292:CALHY RS01550
gene id: 632292:CALHY_RS01550
uniprot id: E4QB70
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS06110
gene id: 632292:CALHY_RS06110
uniprot id: E4Q907
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

632292:CALHY RS10800
gene id: 632292:CALHY_RS10800
uniprot id: E4Q7J5
names: Similarity
messages: Belongs to the leucine-binding protein family.

632292:CALHY RS05195
gene id: 632292:CALHY_RS05195
uniprot id: E4Q844
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

632292:CALHY RS07695
gene id: 632292:CALHY_RS07695
uniprot id: E4QBE1
names: Similarity
messages: Belongs to the UPF0297 family.

632292:CALHY RS08530
gene id: 632292:CALHY_RS08530
uniprot id: E4QCI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

632292:CALHY RS06775
gene id: 632292:CALHY_RS06775
uniprot id: E4QA80
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

632292:CALHY RS10610
gene id: 632292:CALHY_RS10610
uniprot id: E4Q7F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

632292:CALHY RS03030
gene id: 632292:CALHY_RS03030
uniprot id: E4QCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

632292:CALHY RS09530
gene id: 632292:CALHY_RS09530
uniprot id: E4QDH8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS04155
gene id: 632292:CALHY_RS04155
uniprot id: E4QE63
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

632292:CALHY RS07640
gene id: 632292:CALHY_RS07640
uniprot id: E4QBD0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS06245
gene id: 632292:CALHY_RS06245
uniprot id: E4Q9H6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

632292:CALHY RS09670
gene id: 632292:CALHY_RS09670
uniprot id: E4QDK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

632292:CALHY RS13180
gene id: 632292:CALHY_RS13180
uniprot id: E4QAZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

632292:CALHY RS12210
gene id: 632292:CALHY_RS12210
uniprot id: E4Q958
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

632292:CALHY RS08420
gene id: 632292:CALHY_RS08420
uniprot id: E4QC86
names: Similarity
messages: Belongs to the MotB family.

632292:CALHY RS04840
gene id: 632292:CALHY_RS04840
uniprot id: E4Q7Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

632292:CALHY RS04165
gene id: 632292:CALHY_RS04165
uniprot id: E4QE65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

632292:CALHY RS11090
gene id: 632292:CALHY_RS11090
uniprot id: E4Q7Y0
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS09645
gene id: 632292:CALHY_RS09645
uniprot id: E4QDK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS03335
gene id: 632292:CALHY_RS03335
uniprot id: E4QDA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

632292:CALHY RS11070
gene id: 632292:CALHY_RS11070
uniprot id: E4Q7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS08770
gene id: 632292:CALHY_RS08770
uniprot id: E4QCM9
names: Similarity
messages: Belongs to the asp23 family.

632292:CALHY RS05345
gene id: 632292:CALHY_RS05345
uniprot id: E4Q868
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS06285
gene id: 632292:CALHY_RS06285
uniprot id: E4Q9I4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

632292:CALHY RS03495
gene id: 632292:CALHY_RS03495
uniprot id: E4QDD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS02065
gene id: 632292:CALHY_RS02065
uniprot id: E4QBY0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632292:CALHY RS10815
gene id: 632292:CALHY_RS10815
uniprot id: E4Q7J8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

632292:CALHY RS04865
gene id: 632292:CALHY_RS04865
uniprot id: E4Q7Q5
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS04240
gene id: 632292:CALHY_RS04240
uniprot id: E4QE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05855
gene id: 632292:CALHY_RS05855
uniprot id: E4Q8W1
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08830
gene id: 632292:CALHY_RS08830
uniprot id: E4QCP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

632292:CALHY RS03560
gene id: 632292:CALHY_RS03560
uniprot id: E4QDM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS09950
gene id: 632292:CALHY_RS09950
uniprot id: E4QDY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

632292:CALHY RS02655
gene id: 632292:CALHY_RS02655
uniprot id: E4QCH0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

632292:CALHY RS10315
gene id: 632292:CALHY_RS10315
uniprot id: E4QEC8
names: Similarity
messages: Belongs to the PGI/PMI family.

632292:CALHY RS09235
gene id: 632292:CALHY_RS09235
uniprot id: E4QD43
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS03300
gene id: 632292:CALHY_RS03300
uniprot id: E4QD94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

632292:CALHY RS09335
gene id: 632292:CALHY_RS09335
uniprot id: E4QDD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

632292:CALHY RS03475
gene id: 632292:CALHY_RS03475
uniprot id: E4QDC6
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

632292:CALHY RS11520
gene id: 632292:CALHY_RS11520
uniprot id: E4Q8D0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

632292:CALHY RS06575
gene id: 632292:CALHY_RS06575
uniprot id: E4Q9P0
names: Similarity
messages: Belongs to the GARS family.

632292:CALHY RS04615
gene id: 632292:CALHY_RS04615
uniprot id: E4Q7D2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

632292:CALHY RS12395
gene id: 632292:CALHY_RS12395
uniprot id: E4Q994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS11175
gene id: 632292:CALHY_RS11175
uniprot id: E4Q7Z7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

632292:CALHY RS07020
gene id: 632292:CALHY_RS07020
uniprot id: E4QAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

632292:CALHY RS08265
gene id: 632292:CALHY_RS08265
uniprot id: E4QC55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12370
gene id: 632292:CALHY_RS12370
uniprot id: E4Q989
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12500
gene id: 632292:CALHY_RS12500
uniprot id: E4Q9Q9
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08220
gene id: 632292:CALHY_RS08220
uniprot id: E4QC46
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

632292:CALHY RS12110
gene id: 632292:CALHY_RS12110
uniprot id: E4Q938
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS02550
gene id: 632292:CALHY_RS02550
uniprot id: E4QCE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

632292:CALHY RS10230
gene id: 632292:CALHY_RS10230
uniprot id: E4QEB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

632292:CALHY RS04060
gene id: 632292:CALHY_RS04060
uniprot id: E4QE46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

632292:CALHY RS12545
gene id: 632292:CALHY_RS12545
uniprot id: E4Q9R7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

632292:CALHY RS07600
gene id: 632292:CALHY_RS07600
uniprot id: E4QBC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

632292:CALHY RS08555
gene id: 632292:CALHY_RS08555
uniprot id: E4QCI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

632292:CALHY RS00340
gene id: 632292:CALHY_RS00340
uniprot id: E4Q9F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS10390
gene id: 632292:CALHY_RS10390
uniprot id: E4QEE3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS13165
gene id: 632292:CALHY_RS13165
uniprot id: E4QAZ0
names: Similarity
messages: Belongs to the ParB family.

632292:CALHY RS13005
gene id: 632292:CALHY_RS13005
uniprot id: E4QAF9
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS06960
gene id: 632292:CALHY_RS06960
uniprot id: E4QAB5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

632292:CALHY RS10405
gene id: 632292:CALHY_RS10405
uniprot id: E4QEE6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

632292:CALHY RS03355
gene id: 632292:CALHY_RS03355
uniprot id: E4QDA5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

632292:CALHY RS10030
gene id: 632292:CALHY_RS10030
uniprot id: E4QDZ8
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07345
gene id: 632292:CALHY_RS07345
uniprot id: E4QAY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

632292:CALHY RS09980
gene id: 632292:CALHY_RS09980
uniprot id: E4QDY8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

632292:CALHY RS07575
gene id: 632292:CALHY_RS07575
uniprot id: E4QBB7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

632292:CALHY RS07290
gene id: 632292:CALHY_RS07290
uniprot id: E4QAX6
names: Similarity
messages: Belongs to the TlyA family.

632292:CALHY RS11890
gene id: 632292:CALHY_RS11890
uniprot id: E4Q8S0
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07460
gene id: 632292:CALHY_RS07460
uniprot id: E4QB94
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

632292:CALHY RS13040
gene id: 632292:CALHY_RS13040
uniprot id: E4QAG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

632292:CALHY RS07115
gene id: 632292:CALHY_RS07115
uniprot id: E4QAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

632292:CALHY RS06440
gene id: 632292:CALHY_RS06440
uniprot id: E4Q9L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

632292:CALHY RS08495
gene id: 632292:CALHY_RS08495
uniprot id: E4QCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

632292:CALHY RS06380
gene id: 632292:CALHY_RS06380
uniprot id: E4Q9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

632292:CALHY RS12290
gene id: 632292:CALHY_RS12290
uniprot id: E4Q973
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS12710
gene id: 632292:CALHY_RS12710
uniprot id: E4Q9V0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS07925
gene id: 632292:CALHY_RS07925
uniprot id: E4QBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

632292:CALHY RS02270
gene id: 632292:CALHY_RS02270
uniprot id: E4QC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS09510
gene id: 632292:CALHY_RS09510
uniprot id: E4QDH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

632292:CALHY RS06305
gene id: 632292:CALHY_RS06305
uniprot id: E4Q9I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

632292:CALHY RS04585
gene id: 632292:CALHY_RS04585
uniprot id: E4Q7C6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

632292:CALHY RS08705
gene id: 632292:CALHY_RS08705
uniprot id: E4QCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS08920
gene id: 632292:CALHY_RS08920
uniprot id: E4QCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

632292:CALHY RS11370
gene id: 632292:CALHY_RS11370
uniprot id: E4Q8A4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

632292:CALHY RS08855
gene id: 632292:CALHY_RS08855
uniprot id: E4QCP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

632292:CALHY RS06590
gene id: 632292:CALHY_RS06590
uniprot id: E4QA42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

632292:CALHY RS07665
gene id: 632292:CALHY_RS07665
uniprot id: E4QBD5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

632292:CALHY RS08590
gene id: 632292:CALHY_RS08590
uniprot id: E4QCJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

632292:CALHY RS00990
gene id: 632292:CALHY_RS00990
uniprot id: E4QAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS06155
gene id: 632292:CALHY_RS06155
uniprot id: E4Q916
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

632292:CALHY RS04045
gene id: 632292:CALHY_RS04045
uniprot id: E4QE43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

632292:CALHY RS06770
gene id: 632292:CALHY_RS06770
uniprot id: E4QA79
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

632292:CALHY RS10095
gene id: 632292:CALHY_RS10095
uniprot id: E4QE82
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

632292:CALHY RS06830
gene id: 632292:CALHY_RS06830
uniprot id: E4QA89
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07070
gene id: 632292:CALHY_RS07070
uniprot id: E4QAT0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

632292:CALHY RS03070
gene id: 632292:CALHY_RS03070
uniprot id: E4QCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

632292:CALHY RS12220
gene id: 632292:CALHY_RS12220
uniprot id: E4Q960
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS04135
gene id: 632292:CALHY_RS04135
uniprot id: E4QE59
names: Similarity
messages: Belongs to the UPF0735 family.

632292:CALHY RS10365
gene id: 632292:CALHY_RS10365
uniprot id: E4QED8
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

632292:CALHY RS12390
gene id: 632292:CALHY_RS12390
uniprot id: E4Q993
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS06675
gene id: 632292:CALHY_RS06675
uniprot id: E4QA60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

632292:CALHY RS06555
gene id: 632292:CALHY_RS06555
uniprot id: E4Q9N6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

632292:CALHY RS05880
gene id: 632292:CALHY_RS05880
uniprot id: E4Q8W6
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

632292:CALHY RS02525
gene id: 632292:CALHY_RS02525
uniprot id: E4QCE4
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

632292:CALHY RS10685
gene id: 632292:CALHY_RS10685
uniprot id: E4Q7H3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS07965
gene id: 632292:CALHY_RS07965
uniprot id: E4QBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

632292:CALHY RS09385
gene id: 632292:CALHY_RS09385
uniprot id: E4QDE9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

632292:CALHY RS10990
gene id: 632292:CALHY_RS10990
uniprot id: E4Q7W1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

632292:CALHY RS09705
gene id: 632292:CALHY_RS09705
uniprot id: E4QDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

632292:CALHY RS02965
gene id: 632292:CALHY_RS02965
uniprot id: E4QCV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

632292:CALHY RS08975
gene id: 632292:CALHY_RS08975
uniprot id: E4QCZ3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

632292:CALHY RS10415
gene id: 632292:CALHY_RS10415
uniprot id: E4QEE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS07295
gene id: 632292:CALHY_RS07295
uniprot id: E4QAX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

632292:CALHY RS08945
gene id: 632292:CALHY_RS08945
uniprot id: E4QCY7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

632292:CALHY RS03520
gene id: 632292:CALHY_RS03520
uniprot id: E4QDL4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

632292:CALHY RS02000
gene id: 632292:CALHY_RS02000
uniprot id: E4QBW7
names: Similarity
messages: Belongs to the peptidase A24 family.

632292:CALHY RS13140
gene id: 632292:CALHY_RS13140
uniprot id: E4QAI7
names: Similarity
messages: Belongs to the class-I fumarase family.

632292:CALHY RS07105
gene id: 632292:CALHY_RS07105
uniprot id: E4QAT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

632292:CALHY RS00125
gene id: 632292:CALHY_RS00125
uniprot id: E4Q9B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

632292:CALHY RS11695
gene id: 632292:CALHY_RS11695
uniprot id: E4Q8N6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

632292:CALHY RS09740
gene id: 632292:CALHY_RS09740
uniprot id: E4QDU7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

632292:CALHY RS07075
gene id: 632292:CALHY_RS07075
uniprot id: E4QAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

632292:CALHY RS00850
gene id: 632292:CALHY_RS00850
uniprot id: E4QAK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS10375
gene id: 632292:CALHY_RS10375
uniprot id: E4QEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS08600
gene id: 632292:CALHY_RS08600
uniprot id: E4QCJ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS04855
gene id: 632292:CALHY_RS04855
uniprot id: E4Q7Q3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

632292:CALHY RS08715
gene id: 632292:CALHY_RS08715
uniprot id: E4QCL8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

632292:CALHY RS12120
gene id: 632292:CALHY_RS12120
uniprot id: E4Q940
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

632292:CALHY RS05930
gene id: 632292:CALHY_RS05930
uniprot id: E4Q8X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

632292:CALHY RS02720
gene id: 632292:CALHY_RS02720
uniprot id: E4QCR0
names: Similarity
messages: Belongs to the ribulokinase family.

632292:CALHY RS08750
gene id: 632292:CALHY_RS08750
uniprot id: E4QCM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

632292:CALHY RS06290
gene id: 632292:CALHY_RS06290
uniprot id: E4Q9I5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

632292:CALHY RS13235
gene id: 632292:CALHY_RS13235
uniprot id: E4QB03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

632292:CALHY RS00950
gene id: 632292:CALHY_RS00950
uniprot id: E4QAL9
names: Similarity
messages: Belongs to the peptidase S41A family.

632292:CALHY RS09120
gene id: 632292:CALHY_RS09120
uniprot id: E4QD22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

632292:CALHY RS06595
gene id: 632292:CALHY_RS06595
uniprot id: E4QA43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

632292:CALHY RS00440
gene id: 632292:CALHY_RS00440
uniprot id: E4Q9X5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

632292:CALHY RS12475
gene id: 632292:CALHY_RS12475
uniprot id: E4Q9Q4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

632292:CALHY RS12555
gene id: 632292:CALHY_RS12555
uniprot id: E4Q9R9
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

632292:CALHY RS11120
gene id: 632292:CALHY_RS11120
uniprot id: E4Q7Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS11900
gene id: 632292:CALHY_RS11900
uniprot id: E4Q8S2
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08390
gene id: 632292:CALHY_RS08390
uniprot id: E4QC80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

632292:CALHY RS05180
gene id: 632292:CALHY_RS05180
uniprot id: E4Q841
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

632292:CALHY RS08925
gene id: 632292:CALHY_RS08925
uniprot id: E4QCY3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

632292:CALHY RS11395
gene id: 632292:CALHY_RS11395
uniprot id: E4Q8A9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

632292:CALHY RS11270
gene id: 632292:CALHY_RS11270
uniprot id: E4Q886
names: Similarity
messages: Belongs to the sigma-70 factor family.

632292:CALHY RS09225
gene id: 632292:CALHY_RS09225
uniprot id: E4QD41
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08915
gene id: 632292:CALHY_RS08915
uniprot id: E4QCQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

632292:CALHY RS09255
gene id: 632292:CALHY_RS09255
uniprot id: E4QD47
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

632292:CALHY RS05435
gene id: 632292:CALHY_RS05435
uniprot id: E4Q8F5
names: Similarity
messages: Belongs to the FlgM family.

632292:CALHY RS05050
gene id: 632292:CALHY_RS05050
uniprot id: E4Q815
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

632292:CALHY RS04510
gene id: 632292:CALHY_RS04510
uniprot id: E4Q7B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

632292:CALHY RS09495
gene id: 632292:CALHY_RS09495
uniprot id: E4QDH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

632292:CALHY RS06570
gene id: 632292:CALHY_RS06570
uniprot id: E4Q9N9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

632292:CALHY RS09805
gene id: 632292:CALHY_RS09805
uniprot id: E4QDV5
names: Subcellular Location Annotation
messages: Cytoplasm

632292:CALHY RS10875
gene id: 632292:CALHY_RS10875
uniprot id: E4Q7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS07670
gene id: 632292:CALHY_RS07670
uniprot id: E4QBD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

632292:CALHY RS12800
gene id: 632292:CALHY_RS12800
uniprot id: E4QAB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS07830
gene id: 632292:CALHY_RS07830
uniprot id: E4QBP3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

632292:CALHY RS06270
gene id: 632292:CALHY_RS06270
uniprot id: E4Q9I1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

632292:CALHY RS09680
gene id: 632292:CALHY_RS09680
uniprot id: E4QDK8
names: Similarity
messages: Belongs to the transpeptidase family.

632292:CALHY RS03655
gene id: 632292:CALHY_RS03655
uniprot id: E4QDP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

632292:CALHY RS11580
gene id: 632292:CALHY_RS11580
uniprot id: E4Q8E1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

632292:CALHY RS09340
gene id: 632292:CALHY_RS09340
uniprot id: E4QDE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

632292:CALHY RS04395
gene id: 632292:CALHY_RS04395
uniprot id: E4Q787
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

632292:CALHY RS11735
gene id: 632292:CALHY_RS11735
uniprot id: E4Q8P4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS12785
gene id: 632292:CALHY_RS12785
uniprot id: E4Q9W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

632292:CALHY RS07215
gene id: 632292:CALHY_RS07215
uniprot id: E4QAW1
names: Similarity
messages: Belongs to the class-D beta-lactamase family.
messages: Belongs to the transpeptidase family.

632292:CALHY RS08155
gene id: 632292:CALHY_RS08155
uniprot id: E4QC33
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

632292:CALHY RS07365
gene id: 632292:CALHY_RS07365
uniprot id: E4QB75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

632292:CALHY RS00460
gene id: 632292:CALHY_RS00460
uniprot id: E4Q9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS07750
gene id: 632292:CALHY_RS07750
uniprot id: E4QBM7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

632292:CALHY RS07410
gene id: 632292:CALHY_RS07410
uniprot id: E4QB84
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

632292:CALHY RS10190
gene id: 632292:CALHY_RS10190
uniprot id: E4QEA2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

632292:CALHY RS08060
gene id: 632292:CALHY_RS08060
uniprot id: E4QBU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

632292:CALHY RS11400
gene id: 632292:CALHY_RS11400
uniprot id: E4Q8B0
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

632292:CALHY RS10325
gene id: 632292:CALHY_RS10325
uniprot id: E4QED0
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

632292:CALHY RS09295
gene id: 632292:CALHY_RS09295
uniprot id: E4QD55
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

632292:CALHY RS06700
gene id: 632292:CALHY_RS06700
uniprot id: E4QA65
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

632292:CALHY RS06500
gene id: 632292:CALHY_RS06500
uniprot id: E4Q9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

632292:CALHY RS10335
gene id: 632292:CALHY_RS10335
uniprot id: E4QED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05110
gene id: 632292:CALHY_RS05110
uniprot id: E4Q827
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

632292:CALHY RS08485
gene id: 632292:CALHY_RS08485
uniprot id: E4QC99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS07675
gene id: 632292:CALHY_RS07675
uniprot id: E4QBD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

632292:CALHY RS02945
gene id: 632292:CALHY_RS02945
uniprot id: E4QCU9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

632292:CALHY RS11385
gene id: 632292:CALHY_RS11385
uniprot id: E4Q8A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05970
gene id: 632292:CALHY_RS05970
uniprot id: E4Q8Y2
names: Similarity
messages: Belongs to the CapA family.

632292:CALHY RS03380
gene id: 632292:CALHY_RS03380
uniprot id: E4QDB0
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS04680
gene id: 632292:CALHY_RS04680
uniprot id: E4Q7L8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

632292:CALHY RS02420
gene id: 632292:CALHY_RS02420
uniprot id: E4QCC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

632292:CALHY RS08940
gene id: 632292:CALHY_RS08940
uniprot id: E4QCY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

632292:CALHY RS11965
gene id: 632292:CALHY_RS11965
uniprot id: E4Q8T5
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08245
gene id: 632292:CALHY_RS08245
uniprot id: E4QC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS01030
gene id: 632292:CALHY_RS01030
uniprot id: E4QAN5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

632292:CALHY RS09735
gene id: 632292:CALHY_RS09735
uniprot id: E4QDU6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

632292:CALHY RS00705
gene id: 632292:CALHY_RS00705
uniprot id: E4QA27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS00160
gene id: 632292:CALHY_RS00160
uniprot id: E4Q9C2
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS09970
gene id: 632292:CALHY_RS09970
uniprot id: E4QDY6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

632292:CALHY RS05570
gene id: 632292:CALHY_RS05570
uniprot id: E4Q8H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

632292:CALHY RS00030
gene id: 632292:CALHY_RS00030
uniprot id: E4Q9A1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

632292:CALHY RS01360
gene id: 632292:CALHY_RS01360
uniprot id: E4QB42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

632292:CALHY RS03330
gene id: 632292:CALHY_RS03330
uniprot id: E4QDA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

632292:CALHY RS06340
gene id: 632292:CALHY_RS06340
uniprot id: E4Q9J5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

632292:CALHY RS08335
gene id: 632292:CALHY_RS08335
uniprot id: E4QC69
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

632292:CALHY RS04220
gene id: 632292:CALHY_RS04220
uniprot id: E4QE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS03615
gene id: 632292:CALHY_RS03615
uniprot id: E4QDN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

632292:CALHY RS02905
gene id: 632292:CALHY_RS02905
uniprot id: E4QCU1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

632292:CALHY RS05235
gene id: 632292:CALHY_RS05235
uniprot id: E4Q850
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

632292:CALHY RS00725
gene id: 632292:CALHY_RS00725
uniprot id: E4QA31
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

632292:CALHY RS05220
gene id: 632292:CALHY_RS05220
uniprot id: E4Q847
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

632292:CALHY RS04710
gene id: 632292:CALHY_RS04710
uniprot id: E4Q7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

632292:CALHY RS08330
gene id: 632292:CALHY_RS08330
uniprot id: E4QC68
names: Similarity
messages: Belongs to the HupF/HypC family.

632292:CALHY RS13205
gene id: 632292:CALHY_RS13205
uniprot id: E4QAZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

632292:CALHY RS10205
gene id: 632292:CALHY_RS10205
uniprot id: E4QEA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

632292:CALHY RS05950
gene id: 632292:CALHY_RS05950
uniprot id: E4Q8X9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

632292:CALHY RS01145
gene id: 632292:CALHY_RS01145
uniprot id: E4QAQ8
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

632292:CALHY RS10705
gene id: 632292:CALHY_RS10705
uniprot id: E4Q7H7
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS03640
gene id: 632292:CALHY_RS03640
uniprot id: E4QDN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

632292:CALHY RS04960
gene id: 632292:CALHY_RS04960
uniprot id: E4Q7S4
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS12440
gene id: 632292:CALHY_RS12440
uniprot id: E4Q9P7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

632292:CALHY RS06930
gene id: 632292:CALHY_RS06930
uniprot id: E4QAA9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

632292:CALHY RS09890
gene id: 632292:CALHY_RS09890
uniprot id: E4QDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS01460
gene id: 632292:CALHY_RS01460
uniprot id: E4QB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS10515
gene id: 632292:CALHY_RS10515
uniprot id: E4Q7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

632292:CALHY RS09930
gene id: 632292:CALHY_RS09930
uniprot id: E4QDX8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

632292:CALHY RS02695
gene id: 632292:CALHY_RS02695
uniprot id: E4QCH8
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08550
gene id: 632292:CALHY_RS08550
uniprot id: E4QCI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

632292:CALHY RS01900
gene id: 632292:CALHY_RS01900
uniprot id: E4QBL8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

632292:CALHY RS09080
gene id: 632292:CALHY_RS09080
uniprot id: E4QD14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS04720
gene id: 632292:CALHY_RS04720
uniprot id: E4Q7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

632292:CALHY RS11825
gene id: 632292:CALHY_RS11825
uniprot id: E4Q8Q9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS01365
gene id: 632292:CALHY_RS01365
uniprot id: E4QB43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS10290
gene id: 632292:CALHY_RS10290
uniprot id: E4QEC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

632292:CALHY RS12310
gene id: 632292:CALHY_RS12310
uniprot id: E4Q977
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

632292:CALHY RS01545
gene id: 632292:CALHY_RS01545
uniprot id: E4QB69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

632292:CALHY RS04890
gene id: 632292:CALHY_RS04890
uniprot id: E4Q7R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

632292:CALHY RS12435
gene id: 632292:CALHY_RS12435
uniprot id: E4Q9P6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

632292:CALHY RS00965
gene id: 632292:CALHY_RS00965
uniprot id: E4QAM2
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

632292:CALHY RS09350
gene id: 632292:CALHY_RS09350
uniprot id: E4QDE2
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07340
gene id: 632292:CALHY_RS07340
uniprot id: E4QAY5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

632292:CALHY RS03280
gene id: 632292:CALHY_RS03280
uniprot id: E4QD90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

632292:CALHY RS07945
gene id: 632292:CALHY_RS07945
uniprot id: E4QBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS11880
gene id: 632292:CALHY_RS11880
uniprot id: E4Q8R8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

632292:CALHY RS09685
gene id: 632292:CALHY_RS09685
uniprot id: E4QDK9
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS05005
gene id: 632292:CALHY_RS05005
uniprot id: E4Q7T1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS04660
gene id: 632292:CALHY_RS04660
uniprot id: E4Q7L4
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08325
gene id: 632292:CALHY_RS08325
uniprot id: E4QC67
names: Similarity
messages: Belongs to the HypD family.

632292:CALHY RS07500
gene id: 632292:CALHY_RS07500
uniprot id: E4QBA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

632292:CALHY RS06650
gene id: 632292:CALHY_RS06650
uniprot id: E4QA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

632292:CALHY RS12145
gene id: 632292:CALHY_RS12145
uniprot id: E4Q945
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS08090
gene id: 632292:CALHY_RS08090
uniprot id: E4QBU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS00930
gene id: 632292:CALHY_RS00930
uniprot id: E4QAL5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

632292:CALHY RS06525
gene id: 632292:CALHY_RS06525
uniprot id: E4Q9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

632292:CALHY RS10015
gene id: 632292:CALHY_RS10015
uniprot id: E4QDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

632292:CALHY RS08455
gene id: 632292:CALHY_RS08455
uniprot id: E4QC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS02990
gene id: 632292:CALHY_RS02990
uniprot id: E4QCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

632292:CALHY RS09695
gene id: 632292:CALHY_RS09695
uniprot id: E4QDT8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

632292:CALHY RS00470
gene id: 632292:CALHY_RS00470
uniprot id: E4Q9Y1
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

632292:CALHY RS07955
gene id: 632292:CALHY_RS07955
uniprot id: E4QBR9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

632292:CALHY RS12935
gene id: 632292:CALHY_RS12935
uniprot id: E4QAE4
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

632292:CALHY RS06550
gene id: 632292:CALHY_RS06550
uniprot id: E4Q9N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

632292:CALHY RS01105
gene id: 632292:CALHY_RS01105
uniprot id: E4QAQ0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

632292:CALHY RS06335
gene id: 632292:CALHY_RS06335
uniprot id: E4Q9J4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

632292:CALHY RS07630
gene id: 632292:CALHY_RS07630
uniprot id: E4QBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

632292:CALHY RS10330
gene id: 632292:CALHY_RS10330
uniprot id: E4QED1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05945
gene id: 632292:CALHY_RS05945
uniprot id: E4Q8X8
names: Similarity
messages: Belongs to the SleB family.

632292:CALHY RS07525
gene id: 632292:CALHY_RS07525
uniprot id: E4QBA7
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS06405
gene id: 632292:CALHY_RS06405
uniprot id: E4Q9K7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

632292:CALHY RS08185
gene id: 632292:CALHY_RS08185
uniprot id: E4QC39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

632292:CALHY RS09940
gene id: 632292:CALHY_RS09940
uniprot id: E4QDY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

632292:CALHY RS08445
gene id: 632292:CALHY_RS08445
uniprot id: E4QC91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

632292:CALHY RS04905
gene id: 632292:CALHY_RS04905
uniprot id: E4Q7R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

632292:CALHY RS06725
gene id: 632292:CALHY_RS06725
uniprot id: E4QA70
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

632292:CALHY RS07190
gene id: 632292:CALHY_RS07190
uniprot id: E4QAV6
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS03480
gene id: 632292:CALHY_RS03480
uniprot id: E4QDC7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

632292:CALHY RS06240
gene id: 632292:CALHY_RS06240
uniprot id: E4Q9H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

632292:CALHY RS06865
gene id: 632292:CALHY_RS06865
uniprot id: E4QA96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

632292:CALHY RS02885
gene id: 632292:CALHY_RS02885
uniprot id: E4QCT7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

632292:CALHY RS05475
gene id: 632292:CALHY_RS05475
uniprot id: E4Q8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

632292:CALHY RS10395
gene id: 632292:CALHY_RS10395
uniprot id: E4QEE4
names: Subcellular Location Annotation
messages: Nucleus

632292:CALHY RS03020
gene id: 632292:CALHY_RS03020
uniprot id: E4QCW4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

632292:CALHY RS08000
gene id: 632292:CALHY_RS08000
uniprot id: E4QBS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

632292:CALHY RS05145
gene id: 632292:CALHY_RS05145
uniprot id: E4Q834
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

632292:CALHY RS07995
gene id: 632292:CALHY_RS07995
uniprot id: E4QBS7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

632292:CALHY RS04600
gene id: 632292:CALHY_RS04600
uniprot id: E4Q7C9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

632292:CALHY RS10070
gene id: 632292:CALHY_RS10070
uniprot id: E4QE05
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632292:CALHY RS11710
gene id: 632292:CALHY_RS11710
uniprot id: E4Q8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

632292:CALHY RS04230
gene id: 632292:CALHY_RS04230
uniprot id: E4QE78
names: Similarity
messages: Belongs to the EamA transporter family.

632292:CALHY RS10265
gene id: 632292:CALHY_RS10265
uniprot id: E4QEB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS02950
gene id: 632292:CALHY_RS02950
uniprot id: E4QCV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

632292:CALHY RS12770
gene id: 632292:CALHY_RS12770
uniprot id: E4Q9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS07470
gene id: 632292:CALHY_RS07470
uniprot id: E4QB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

632292:CALHY RS06100
gene id: 632292:CALHY_RS06100
uniprot id: E4Q905
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

632292:CALHY RS06425
gene id: 632292:CALHY_RS06425
uniprot id: E4Q9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

632292:CALHY RS07545
gene id: 632292:CALHY_RS07545
uniprot id: E4QBB1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

632292:CALHY RS05935
gene id: 632292:CALHY_RS05935
uniprot id: E4Q8X6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

632292:CALHY RS13200
gene id: 632292:CALHY_RS13200
uniprot id: E4QAZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

632292:CALHY RS07430
gene id: 632292:CALHY_RS07430
uniprot id: E4QB88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

632292:CALHY RS01195
gene id: 632292:CALHY_RS01195
uniprot id: E4QB09
names: Similarity
messages: Belongs to the peptidase C69 family.

632292:CALHY RS13175
gene id: 632292:CALHY_RS13175
uniprot id: E4QAZ2
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632292:CALHY RS13605
gene id: 632292:CALHY_RS13605
uniprot id: E4QB01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

632292:CALHY RS02545
gene id: 632292:CALHY_RS02545
uniprot id: E4QCE8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

632292:CALHY RS04735
gene id: 632292:CALHY_RS04735
uniprot id: E4Q7M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

632292:CALHY RS07230
gene id: 632292:CALHY_RS07230
uniprot id: E4QAW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

632292:CALHY RS09570
gene id: 632292:CALHY_RS09570
uniprot id: E4QDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

632292:CALHY RS06810
gene id: 632292:CALHY_RS06810
uniprot id: E4QA85
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632292:CALHY RS05360
gene id: 632292:CALHY_RS05360
uniprot id: E4Q871
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

632292:CALHY RS04715
gene id: 632292:CALHY_RS04715
uniprot id: E4Q7M5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS01475
gene id: 632292:CALHY_RS01475
uniprot id: E4QB60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

632292:CALHY RS06280
gene id: 632292:CALHY_RS06280
uniprot id: E4Q9I3
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

632292:CALHY RS11690
gene id: 632292:CALHY_RS11690
uniprot id: E4Q8N5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

632292:CALHY RS04580
gene id: 632292:CALHY_RS04580
uniprot id: E4Q7C5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

632292:CALHY RS08835
gene id: 632292:CALHY_RS08835
uniprot id: E4QCP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

632292:CALHY RS07465
gene id: 632292:CALHY_RS07465
uniprot id: E4QB95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

632292:CALHY RS07245
gene id: 632292:CALHY_RS07245
uniprot id: E4QAW7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

632292:CALHY RS11200
gene id: 632292:CALHY_RS11200
uniprot id: E4Q802
names: Similarity
messages: Belongs to the hemerythrin family.

632292:CALHY RS09135
gene id: 632292:CALHY_RS09135
uniprot id: E4QD25
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

632292:CALHY RS00315
gene id: 632292:CALHY_RS00315
uniprot id: E4Q9F4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS07060
gene id: 632292:CALHY_RS07060
uniprot id: E4QAS8
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS07005
gene id: 632292:CALHY_RS07005
uniprot id: E4QAR7
names: Subcellular Location Annotation
messages: Cytoplasm

632292:CALHY RS12945
gene id: 632292:CALHY_RS12945
uniprot id: E4QAE6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

632292:CALHY RS07000
gene id: 632292:CALHY_RS07000
uniprot id: E4QAR6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

632292:CALHY RS05615
gene id: 632292:CALHY_RS05615
uniprot id: E4Q8I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

632292:CALHY RS09205
gene id: 632292:CALHY_RS09205
uniprot id: E4QD38
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

632292:CALHY RS02980
gene id: 632292:CALHY_RS02980
uniprot id: E4QCV6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

632292:CALHY RS09650
gene id: 632292:CALHY_RS09650
uniprot id: E4QDK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS06420
gene id: 632292:CALHY_RS06420
uniprot id: E4Q9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

632292:CALHY RS08845
gene id: 632292:CALHY_RS08845
uniprot id: E4QCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

632292:CALHY RS07930
gene id: 632292:CALHY_RS07930
uniprot id: E4QBR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

632292:CALHY RS12605
gene id: 632292:CALHY_RS12605
uniprot id: E4Q9S9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

632292:CALHY RS12815
gene id: 632292:CALHY_RS12815
uniprot id: E4QAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

632292:CALHY RS12010
gene id: 632292:CALHY_RS12010
uniprot id: E4Q8U3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632292:CALHY RS11255
gene id: 632292:CALHY_RS11255
uniprot id: E4Q883
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

632292:CALHY RS00995
gene id: 632292:CALHY_RS00995
uniprot id: E4QAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS00580
gene id: 632292:CALHY_RS00580
uniprot id: E4QA03
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08105
gene id: 632292:CALHY_RS08105
uniprot id: E4QBU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

632292:CALHY RS08505
gene id: 632292:CALHY_RS08505
uniprot id: E4QCA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

632292:CALHY RS04765
gene id: 632292:CALHY_RS04765
uniprot id: E4Q7N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

632292:CALHY RS13185
gene id: 632292:CALHY_RS13185
uniprot id: E4QAZ4
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

632292:CALHY RS05065
gene id: 632292:CALHY_RS05065
uniprot id: E4Q818
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

632292:CALHY RS06670
gene id: 632292:CALHY_RS06670
uniprot id: E4QA59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

632292:CALHY RS05985
gene id: 632292:CALHY_RS05985
uniprot id: E4Q8Y5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

632292:CALHY RS02075
gene id: 632292:CALHY_RS02075
uniprot id: E4QBY3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

632292:CALHY RS12050
gene id: 632292:CALHY_RS12050
uniprot id: E4Q926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS02370
gene id: 632292:CALHY_RS02370
uniprot id: E4QCB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

632292:CALHY RS07530
gene id: 632292:CALHY_RS07530
uniprot id: E4QBA8
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07080
gene id: 632292:CALHY_RS07080
uniprot id: E4QAT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS12045
gene id: 632292:CALHY_RS12045
uniprot id: E4Q925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12125
gene id: 632292:CALHY_RS12125
uniprot id: E4Q941
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

632292:CALHY RS11145
gene id: 632292:CALHY_RS11145
uniprot id: E4Q7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

632292:CALHY RS05080
gene id: 632292:CALHY_RS05080
uniprot id: E4Q821
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

632292:CALHY RS00885
gene id: 632292:CALHY_RS00885
uniprot id: E4QAK8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

632292:CALHY RS07755
gene id: 632292:CALHY_RS07755
uniprot id: E4QBM8
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

632292:CALHY RS08900
gene id: 632292:CALHY_RS08900
uniprot id: E4QCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

632292:CALHY RS03075
gene id: 632292:CALHY_RS03075
uniprot id: E4QCX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

632292:CALHY RS08375
gene id: 632292:CALHY_RS08375
uniprot id: E4QC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

632292:CALHY RS10305
gene id: 632292:CALHY_RS10305
uniprot id: E4QEC6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

632292:CALHY RS06105
gene id: 632292:CALHY_RS06105
uniprot id: E4Q906
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

632292:CALHY RS03635
gene id: 632292:CALHY_RS03635
uniprot id: E4QDN6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632292:CALHY RS11535
gene id: 632292:CALHY_RS11535
uniprot id: E4Q8D3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

632292:CALHY RS05610
gene id: 632292:CALHY_RS05610
uniprot id: E4Q8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

632292:CALHY RS00435
gene id: 632292:CALHY_RS00435
uniprot id: E4Q9X4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

632292:CALHY RS05155
gene id: 632292:CALHY_RS05155
uniprot id: E4Q836
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

632292:CALHY RS10955
gene id: 632292:CALHY_RS10955
uniprot id: E4Q7V3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

632292:CALHY RS02955
gene id: 632292:CALHY_RS02955
uniprot id: E4QCV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

632292:CALHY RS05990
gene id: 632292:CALHY_RS05990
uniprot id: E4Q8Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

632292:CALHY RS09665
gene id: 632292:CALHY_RS09665
uniprot id: E4QDK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12610
gene id: 632292:CALHY_RS12610
uniprot id: E4Q9T0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

632292:CALHY RS12730
gene id: 632292:CALHY_RS12730
uniprot id: E4Q9V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS10320
gene id: 632292:CALHY_RS10320
uniprot id: E4QEC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632292:CALHY RS12600
gene id: 632292:CALHY_RS12600
uniprot id: E4Q9S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

632292:CALHY RS12870
gene id: 632292:CALHY_RS12870
uniprot id: E4QAD0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

632292:CALHY RS07550
gene id: 632292:CALHY_RS07550
uniprot id: E4QBB2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

632292:CALHY RS10420
gene id: 632292:CALHY_RS10420
uniprot id: E4QEE9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS08880
gene id: 632292:CALHY_RS08880
uniprot id: E4QCQ1
names: Similarity
messages: Belongs to the UPF0102 family.

632292:CALHY RS00860
gene id: 632292:CALHY_RS00860
uniprot id: E4QAK3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

632292:CALHY RS08905
gene id: 632292:CALHY_RS08905
uniprot id: E4QCQ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

632292:CALHY RS06720
gene id: 632292:CALHY_RS06720
uniprot id: E4QA69
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

632292:CALHY RS05075
gene id: 632292:CALHY_RS05075
uniprot id: E4Q820
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

632292:CALHY RS10625
gene id: 632292:CALHY_RS10625
uniprot id: E4Q7G1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

632292:CALHY RS10080
gene id: 632292:CALHY_RS10080
uniprot id: E4QE07
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632292:CALHY RS07045
gene id: 632292:CALHY_RS07045
uniprot id: E4QAS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

632292:CALHY RS06260
gene id: 632292:CALHY_RS06260
uniprot id: E4Q9H9
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

632292:CALHY RS04900
gene id: 632292:CALHY_RS04900
uniprot id: E4Q7R2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

632292:CALHY RS05550
gene id: 632292:CALHY_RS05550
uniprot id: E4Q8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

632292:CALHY RS05230
gene id: 632292:CALHY_RS05230
uniprot id: E4Q849
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS00240
gene id: 632292:CALHY_RS00240
uniprot id: E4Q9D9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS10985
gene id: 632292:CALHY_RS10985
uniprot id: E4Q7W0
names: Similarity
messages: Belongs to the YoeB family.

632292:CALHY RS06015
gene id: 632292:CALHY_RS06015
uniprot id: E4Q8Z1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

632292:CALHY RS05630
gene id: 632292:CALHY_RS05630
uniprot id: E4Q8J0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

632292:CALHY RS02505
gene id: 632292:CALHY_RS02505
uniprot id: E4QCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05085
gene id: 632292:CALHY_RS05085
uniprot id: E4Q822
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

632292:CALHY RS04415
gene id: 632292:CALHY_RS04415
uniprot id: E4Q791
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

632292:CALHY RS12115
gene id: 632292:CALHY_RS12115
uniprot id: E4Q939
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS13045
gene id: 632292:CALHY_RS13045
uniprot id: E4QAG7
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

632292:CALHY RS05410
gene id: 632292:CALHY_RS05410
uniprot id: E4Q8F0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

632292:CALHY RS09200
gene id: 632292:CALHY_RS09200
uniprot id: E4QD37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

632292:CALHY RS05060
gene id: 632292:CALHY_RS05060
uniprot id: E4Q817
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

632292:CALHY RS00855
gene id: 632292:CALHY_RS00855
uniprot id: E4QAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12100
gene id: 632292:CALHY_RS12100
uniprot id: E4Q936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS03340
gene id: 632292:CALHY_RS03340
uniprot id: E4QDA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS08500
gene id: 632292:CALHY_RS08500
uniprot id: E4QCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

632292:CALHY RS01290
gene id: 632292:CALHY_RS01290
uniprot id: E4QB28
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632292:CALHY RS10255
gene id: 632292:CALHY_RS10255
uniprot id: E4QEB5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

632292:CALHY RS09455
gene id: 632292:CALHY_RS09455
uniprot id: E4QDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

632292:CALHY RS03010
gene id: 632292:CALHY_RS03010
uniprot id: E4QCW2
names: Similarity
messages: Belongs to the FlgD family.

632292:CALHY RS09675
gene id: 632292:CALHY_RS09675
uniprot id: E4QDK7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS04695
gene id: 632292:CALHY_RS04695
uniprot id: E4Q7M1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS02555
gene id: 632292:CALHY_RS02555
uniprot id: E4QCF1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

632292:CALHY RS07050
gene id: 632292:CALHY_RS07050
uniprot id: E4QAS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

632292:CALHY RS06620
gene id: 632292:CALHY_RS06620
uniprot id: E4QA48
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

632292:CALHY RS08435
gene id: 632292:CALHY_RS08435
uniprot id: E4QC89
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

632292:CALHY RS06125
gene id: 632292:CALHY_RS06125
uniprot id: E4Q910
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

632292:CALHY RS09635
gene id: 632292:CALHY_RS09635
uniprot id: E4QDJ9
names: Similarity
messages: Belongs to the UPF0749 family.

632292:CALHY RS06870
gene id: 632292:CALHY_RS06870
uniprot id: E4QA97
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS01095
gene id: 632292:CALHY_RS01095
uniprot id: E4QAP8
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08585
gene id: 632292:CALHY_RS08585
uniprot id: E4QCJ4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

632292:CALHY RS01110
gene id: 632292:CALHY_RS01110
uniprot id: E4QAQ1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

632292:CALHY RS12695
gene id: 632292:CALHY_RS12695
uniprot id: E4Q9U7
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS04760
gene id: 632292:CALHY_RS04760
uniprot id: E4Q7N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

632292:CALHY RS09605
gene id: 632292:CALHY_RS09605
uniprot id: E4QDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

632292:CALHY RS08235
gene id: 632292:CALHY_RS08235
uniprot id: E4QC49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12540
gene id: 632292:CALHY_RS12540
uniprot id: E4Q9R6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

632292:CALHY RS05980
gene id: 632292:CALHY_RS05980
uniprot id: E4Q8Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632292:CALHY RS02290
gene id: 632292:CALHY_RS02290
uniprot id: E4QC22
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS10285
gene id: 632292:CALHY_RS10285
uniprot id: E4QEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

632292:CALHY RS04685
gene id: 632292:CALHY_RS04685
uniprot id: E4Q7L9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

632292:CALHY RS06050
gene id: 632292:CALHY_RS06050
uniprot id: E4Q8Z8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

632292:CALHY RS08120
gene id: 632292:CALHY_RS08120
uniprot id: E4QBV2
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

632292:CALHY RS04630
gene id: 632292:CALHY_RS04630
uniprot id: E4Q7K8
names: Similarity
messages: Belongs to the CtsR family.

632292:CALHY RS01540
gene id: 632292:CALHY_RS01540
uniprot id: E4QB68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS04145
gene id: 632292:CALHY_RS04145
uniprot id: E4QE61
names: Similarity
messages: Belongs to the GerABKA family.

632292:CALHY RS04655
gene id: 632292:CALHY_RS04655
uniprot id: E4Q7L3
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

632292:CALHY RS04420
gene id: 632292:CALHY_RS04420
uniprot id: E4Q792
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

632292:CALHY RS10620
gene id: 632292:CALHY_RS10620
uniprot id: E4Q7G0
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

632292:CALHY RS09660
gene id: 632292:CALHY_RS09660
uniprot id: E4QDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

632292:CALHY RS06400
gene id: 632292:CALHY_RS06400
uniprot id: E4Q9K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

632292:CALHY RS01870
gene id: 632292:CALHY_RS01870
uniprot id: E4QBL2
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

632292:CALHY RS00790
gene id: 632292:CALHY_RS00790
uniprot id: E4QAJ2
names: Similarity
messages: Belongs to the glutamate synthase family.

632292:CALHY RS07765
gene id: 632292:CALHY_RS07765
uniprot id: E4QBN0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

632292:CALHY RS00110
gene id: 632292:CALHY_RS00110
uniprot id: E4Q9B4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

632292:CALHY RS03045
gene id: 632292:CALHY_RS03045
uniprot id: E4QCW9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS01910
gene id: 632292:CALHY_RS01910
uniprot id: E4QBM1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

632292:CALHY RS10140
gene id: 632292:CALHY_RS10140
uniprot id: E4QE92
names: Similarity
messages: Belongs to the threonine synthase family.

632292:CALHY RS00955
gene id: 632292:CALHY_RS00955
uniprot id: E4QAM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS07325
gene id: 632292:CALHY_RS07325
uniprot id: E4QAY2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

632292:CALHY RS07580
gene id: 632292:CALHY_RS07580
uniprot id: E4QBB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

632292:CALHY RS00445
gene id: 632292:CALHY_RS00445
uniprot id: E4Q9X6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS04065
gene id: 632292:CALHY_RS04065
uniprot id: E4QE47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

632292:CALHY RS00770
gene id: 632292:CALHY_RS00770
uniprot id: E4QA38
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08860
gene id: 632292:CALHY_RS08860
uniprot id: E4QCP7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

632292:CALHY RS05465
gene id: 632292:CALHY_RS05465
uniprot id: E4Q8G1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

632292:CALHY RS04640
gene id: 632292:CALHY_RS04640
uniprot id: E4Q7L0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS00050
gene id: 632292:CALHY_RS00050
uniprot id: E4Q9A4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

632292:CALHY RS11450
gene id: 632292:CALHY_RS11450
uniprot id: E4Q8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

632292:CALHY RS08470
gene id: 632292:CALHY_RS08470
uniprot id: E4QC96
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS09975
gene id: 632292:CALHY_RS09975
uniprot id: E4QDY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

632292:CALHY RS03375
gene id: 632292:CALHY_RS03375
uniprot id: E4QDA9
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07015
gene id: 632292:CALHY_RS07015
uniprot id: E4QAR9
names: Similarity
messages: Belongs to the YggT family.

632292:CALHY RS05365
gene id: 632292:CALHY_RS05365
uniprot id: E4Q872
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

632292:CALHY RS14010
gene id: 632292:CALHY_RS14010
uniprot id: E4QD97
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS11140
gene id: 632292:CALHY_RS11140
uniprot id: E4Q7Z0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

632292:CALHY RS07200
gene id: 632292:CALHY_RS07200
uniprot id: E4QAV8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

632292:CALHY RS04150
gene id: 632292:CALHY_RS04150
uniprot id: E4QE62
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

632292:CALHY RS00130
gene id: 632292:CALHY_RS00130
uniprot id: E4Q9B8
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS05140
gene id: 632292:CALHY_RS05140
uniprot id: E4Q833
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

632292:CALHY RS08825
gene id: 632292:CALHY_RS08825
uniprot id: E4QCP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

632292:CALHY RS01850
gene id: 632292:CALHY_RS01850
uniprot id: E4QBK8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

632292:CALHY RS09925
gene id: 632292:CALHY_RS09925
uniprot id: E4QDX7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

632292:CALHY RS06030
gene id: 632292:CALHY_RS06030
uniprot id: E4Q8Z4
names: Similarity
messages: Belongs to the peptidase M29 family.

632292:CALHY RS06640
gene id: 632292:CALHY_RS06640
uniprot id: E4QA53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

632292:CALHY RS11510
gene id: 632292:CALHY_RS11510
uniprot id: E4Q8C8
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632292:CALHY RS01535
gene id: 632292:CALHY_RS01535
uniprot id: E4QB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

632292:CALHY RS11780
gene id: 632292:CALHY_RS11780
uniprot id: E4Q8Q2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

632292:CALHY RS03445
gene id: 632292:CALHY_RS03445
uniprot id: E4QDC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

632292:CALHY RS06880
gene id: 632292:CALHY_RS06880
uniprot id: E4QA99
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS10730
gene id: 632292:CALHY_RS10730
uniprot id: E4Q7I1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632292:CALHY RS02395
gene id: 632292:CALHY_RS02395
uniprot id: E4QCC0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

632292:CALHY RS09370
gene id: 632292:CALHY_RS09370
uniprot id: E4QDE6
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

632292:CALHY RS12095
gene id: 632292:CALHY_RS12095
uniprot id: E4Q935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05325
gene id: 632292:CALHY_RS05325
uniprot id: E4Q864
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

632292:CALHY RS06250
gene id: 632292:CALHY_RS06250
uniprot id: E4Q9H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

632292:CALHY RS00935
gene id: 632292:CALHY_RS00935
uniprot id: E4QAL6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

632292:CALHY RS08150
gene id: 632292:CALHY_RS08150
uniprot id: E4QC32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

632292:CALHY RS07990
gene id: 632292:CALHY_RS07990
uniprot id: E4QBS6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

632292:CALHY RS09110
gene id: 632292:CALHY_RS09110
uniprot id: E4QD20
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS10940
gene id: 632292:CALHY_RS10940
uniprot id: E4Q7V0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

632292:CALHY RS00015
gene id: 632292:CALHY_RS00015
uniprot id: E4Q998
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

632292:CALHY RS12295
gene id: 632292:CALHY_RS12295
uniprot id: E4Q974
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS10225
gene id: 632292:CALHY_RS10225
uniprot id: E4QEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

632292:CALHY RS12855
gene id: 632292:CALHY_RS12855
uniprot id: E4QAC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

632292:CALHY RS01315
gene id: 632292:CALHY_RS01315
uniprot id: E4QB33
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS09090
gene id: 632292:CALHY_RS09090
uniprot id: E4QD16
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS10050
gene id: 632292:CALHY_RS10050
uniprot id: E4QE02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

632292:CALHY RS08725
gene id: 632292:CALHY_RS08725
uniprot id: E4QCM0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

632292:CALHY RS10640
gene id: 632292:CALHY_RS10640
uniprot id: E4Q7G4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

632292:CALHY RS06820
gene id: 632292:CALHY_RS06820
uniprot id: E4QA87
names: Similarity
messages: Belongs to the leucine-binding protein family.

632292:CALHY RS06055
gene id: 632292:CALHY_RS06055
uniprot id: E4Q8Z9
names: Similarity
messages: Belongs to the asparagine synthetase family.

632292:CALHY RS11670
gene id: 632292:CALHY_RS11670
uniprot id: E4Q8N1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

632292:CALHY RS06410
gene id: 632292:CALHY_RS06410
uniprot id: E4Q9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

632292:CALHY RS08490
gene id: 632292:CALHY_RS08490
uniprot id: E4QCA0
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

632292:CALHY RS11115
gene id: 632292:CALHY_RS11115
uniprot id: E4Q7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS08110
gene id: 632292:CALHY_RS08110
uniprot id: E4QBV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

632292:CALHY RS09820
gene id: 632292:CALHY_RS09820
uniprot id: E4QDV8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

632292:CALHY RS08570
gene id: 632292:CALHY_RS08570
uniprot id: E4QCJ1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

632292:CALHY RS07710
gene id: 632292:CALHY_RS07710
uniprot id: E4QBE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

632292:CALHY RS06630
gene id: 632292:CALHY_RS06630
uniprot id: E4QA50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS07790
gene id: 632292:CALHY_RS07790
uniprot id: E4QBN5
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

632292:CALHY RS06755
gene id: 632292:CALHY_RS06755
uniprot id: E4QA76
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

632292:CALHY RS02565
gene id: 632292:CALHY_RS02565
uniprot id: E4QCF3
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS05115
gene id: 632292:CALHY_RS05115
uniprot id: E4Q828
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

632292:CALHY RS03490
gene id: 632292:CALHY_RS03490
uniprot id: E4QDC9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

632292:CALHY RS08525
gene id: 632292:CALHY_RS08525
uniprot id: E4QCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

632292:CALHY RS06545
gene id: 632292:CALHY_RS06545
uniprot id: E4Q9N4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

632292:CALHY RS05390
gene id: 632292:CALHY_RS05390
uniprot id: E4Q877
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS01075
gene id: 632292:CALHY_RS01075
uniprot id: E4QAP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

632292:CALHY RS03990
gene id: 632292:CALHY_RS03990
uniprot id: E4QE34
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

632292:CALHY RS08175
gene id: 632292:CALHY_RS08175
uniprot id: E4QC37
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

632292:CALHY RS05125
gene id: 632292:CALHY_RS05125
uniprot id: E4Q830
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

632292:CALHY RS11525
gene id: 632292:CALHY_RS11525
uniprot id: E4Q8D1
names: Similarity
messages: Belongs to the ThiD family.

632292:CALHY RS13215
gene id: 632292:CALHY_RS13215
uniprot id: E4QAZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

632292:CALHY RS07400
gene id: 632292:CALHY_RS07400
uniprot id: E4QB82
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

632292:CALHY RS06850
gene id: 632292:CALHY_RS06850
uniprot id: E4QA93
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS08895
gene id: 632292:CALHY_RS08895
uniprot id: E4QCQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

632292:CALHY RS12415
gene id: 632292:CALHY_RS12415
uniprot id: E4Q9P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

632292:CALHY RS05575
gene id: 632292:CALHY_RS05575
uniprot id: E4Q8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

632292:CALHY RS07935
gene id: 632292:CALHY_RS07935
uniprot id: E4QBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

632292:CALHY RS07425
gene id: 632292:CALHY_RS07425
uniprot id: E4QB87
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

632292:CALHY RS11985
gene id: 632292:CALHY_RS11985
uniprot id: E4Q8T8
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS00635
gene id: 632292:CALHY_RS00635
uniprot id: E4QA14
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

632292:CALHY RS12700
gene id: 632292:CALHY_RS12700
uniprot id: E4Q9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12865
gene id: 632292:CALHY_RS12865
uniprot id: E4QAC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

632292:CALHY RS09855
gene id: 632292:CALHY_RS09855
uniprot id: E4QDW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

632292:CALHY RS06345
gene id: 632292:CALHY_RS06345
uniprot id: E4Q9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

632292:CALHY RS02930
gene id: 632292:CALHY_RS02930
uniprot id: E4QCU6
names: Similarity
messages: Belongs to the DprA/Smf family.

632292:CALHY RS05660
gene id: 632292:CALHY_RS05660
uniprot id: E4Q8J4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

632292:CALHY RS05380
gene id: 632292:CALHY_RS05380
uniprot id: E4Q875
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

632292:CALHY RS08970
gene id: 632292:CALHY_RS08970
uniprot id: E4QCZ2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

632292:CALHY RS04835
gene id: 632292:CALHY_RS04835
uniprot id: E4Q7P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

632292:CALHY RS02855
gene id: 632292:CALHY_RS02855
uniprot id: E4QCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

632292:CALHY RS07095
gene id: 632292:CALHY_RS07095
uniprot id: E4QAT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

632292:CALHY RS02850
gene id: 632292:CALHY_RS02850
uniprot id: E4QCT3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

632292:CALHY RS03500
gene id: 632292:CALHY_RS03500
uniprot id: E4QDD1
names: Similarity
messages: Belongs to the P(II) protein family.

632292:CALHY RS05355
gene id: 632292:CALHY_RS05355
uniprot id: E4Q870
names: Similarity
messages: Belongs to the TrpF family.

632292:CALHY RS09800
gene id: 632292:CALHY_RS09800
uniprot id: E4QDV4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

632292:CALHY RS10385
gene id: 632292:CALHY_RS10385
uniprot id: E4QEE2
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08540
gene id: 632292:CALHY_RS08540
uniprot id: E4QCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

632292:CALHY RS10960
gene id: 632292:CALHY_RS10960
uniprot id: E4Q7V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

632292:CALHY RS03035
gene id: 632292:CALHY_RS03035
uniprot id: E4QCW7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

632292:CALHY RS11050
gene id: 632292:CALHY_RS11050
uniprot id: E4Q7X3
names: Similarity
messages: Belongs to the glycosyl hydrolase.

632292:CALHY RS08370
gene id: 632292:CALHY_RS08370
uniprot id: E4QC76
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS05730
gene id: 632292:CALHY_RS05730
uniprot id: E4Q8L0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

632292:CALHY RS08005
gene id: 632292:CALHY_RS08005
uniprot id: E4QBS9
names: Similarity
messages: Belongs to the fabD family.

632292:CALHY RS12715
gene id: 632292:CALHY_RS12715
uniprot id: E4Q9V1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS07445
gene id: 632292:CALHY_RS07445
uniprot id: E4QB91
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

632292:CALHY RS10555
gene id: 632292:CALHY_RS10555
uniprot id: E4Q7E8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

632292:CALHY RS13195
gene id: 632292:CALHY_RS13195
uniprot id: E4QAZ5
names: Similarity
messages: Belongs to the ParB family.

632292:CALHY RS10470
gene id: 632292:CALHY_RS10470
uniprot id: E4Q7D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

632292:CALHY RS06395
gene id: 632292:CALHY_RS06395
uniprot id: E4Q9K5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

632292:CALHY RS09115
gene id: 632292:CALHY_RS09115
uniprot id: E4QD21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS02310
gene id: 632292:CALHY_RS02310
uniprot id: E4QC26
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS02300
gene id: 632292:CALHY_RS02300
uniprot id: E4QC24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

632292:CALHY RS10235
gene id: 632292:CALHY_RS10235
uniprot id: E4QEB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

632292:CALHY RS03205
gene id: 632292:CALHY_RS03205
uniprot id: E4QD75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

632292:CALHY RS04125
gene id: 632292:CALHY_RS04125
uniprot id: E4QE57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

632292:CALHY RS10535
gene id: 632292:CALHY_RS10535
uniprot id: E4Q7E5
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

632292:CALHY RS10615
gene id: 632292:CALHY_RS10615
uniprot id: E4Q7F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

632292:CALHY RS07315
gene id: 632292:CALHY_RS07315
uniprot id: E4QAY0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

632292:CALHY RS06000
gene id: 632292:CALHY_RS06000
uniprot id: E4Q8Y8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

632292:CALHY RS09240
gene id: 632292:CALHY_RS09240
uniprot id: E4QD44
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

632292:CALHY RS04120
gene id: 632292:CALHY_RS04120
uniprot id: E4QE56
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

632292:CALHY RS11290
gene id: 632292:CALHY_RS11290
uniprot id: E4Q890
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

632292:CALHY RS02645
gene id: 632292:CALHY_RS02645
uniprot id: E4QCG8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

632292:CALHY RS11875
gene id: 632292:CALHY_RS11875
uniprot id: E4Q8R7
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

632292:CALHY RS09575
gene id: 632292:CALHY_RS09575
uniprot id: E4QDI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

632292:CALHY RS05070
gene id: 632292:CALHY_RS05070
uniprot id: E4Q819
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

632292:CALHY RS05290
gene id: 632292:CALHY_RS05290
uniprot id: E4Q857
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS00135
gene id: 632292:CALHY_RS00135
uniprot id: E4Q9B9
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS03400
gene id: 632292:CALHY_RS03400
uniprot id: E4QDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS06315
gene id: 632292:CALHY_RS06315
uniprot id: E4Q9J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

632292:CALHY RS12940
gene id: 632292:CALHY_RS12940
uniprot id: E4QAE5
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

632292:CALHY RS06415
gene id: 632292:CALHY_RS06415
uniprot id: E4Q9K9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

632292:CALHY RS09460
gene id: 632292:CALHY_RS09460
uniprot id: E4QDG4
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07090
gene id: 632292:CALHY_RS07090
uniprot id: E4QAT4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

632292:CALHY RS04495
gene id: 632292:CALHY_RS04495
uniprot id: E4Q7A8
names: Similarity
messages: Belongs to the peptidase C40 family.

632292:CALHY RS09400
gene id: 632292:CALHY_RS09400
uniprot id: E4QDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS00400
gene id: 632292:CALHY_RS00400
uniprot id: E4Q9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS09140
gene id: 632292:CALHY_RS09140
uniprot id: E4QD26
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

632292:CALHY RS07475
gene id: 632292:CALHY_RS07475
uniprot id: E4QB97
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

632292:CALHY RS06665
gene id: 632292:CALHY_RS06665
uniprot id: E4QA58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

632292:CALHY RS00345
gene id: 632292:CALHY_RS00345
uniprot id: E4Q9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS02480
gene id: 632292:CALHY_RS02480
uniprot id: E4QCD5
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07025
gene id: 632292:CALHY_RS07025
uniprot id: E4QAS1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

632292:CALHY RS00960
gene id: 632292:CALHY_RS00960
uniprot id: E4QAM1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

632292:CALHY RS11060
gene id: 632292:CALHY_RS11060
uniprot id: E4Q7X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

632292:CALHY RS05105
gene id: 632292:CALHY_RS05105
uniprot id: E4Q826
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

632292:CALHY RS08400
gene id: 632292:CALHY_RS08400
uniprot id: E4QC82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

632292:CALHY RS03895
gene id: 632292:CALHY_RS03895
uniprot id: E4QE15
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

632292:CALHY RS00075
gene id: 632292:CALHY_RS00075
uniprot id: E4Q9A9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

632292:CALHY RS07625
gene id: 632292:CALHY_RS07625
uniprot id: E4QBC7
names: Similarity
messages: Belongs to the asp23 family.

632292:CALHY RS04795
gene id: 632292:CALHY_RS04795
uniprot id: E4Q7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

632292:CALHY RS01555
gene id: 632292:CALHY_RS01555
uniprot id: E4QB71
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

632292:CALHY RS03235
gene id: 632292:CALHY_RS03235
uniprot id: E4QD81
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

632292:CALHY RS03645
gene id: 632292:CALHY_RS03645
uniprot id: E4QDN8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

632292:CALHY RS01040
gene id: 632292:CALHY_RS01040
uniprot id: E4QAN7
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS08630
gene id: 632292:CALHY_RS08630
uniprot id: E4QCK3
names: Similarity
messages: Belongs to the histone deacetylase family.

632292:CALHY RS03575
gene id: 632292:CALHY_RS03575
uniprot id: E4QDM4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

632292:CALHY RS06325
gene id: 632292:CALHY_RS06325
uniprot id: E4Q9J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

632292:CALHY RS07320
gene id: 632292:CALHY_RS07320
uniprot id: E4QAY1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

632292:CALHY RS06635
gene id: 632292:CALHY_RS06635
uniprot id: E4QA51
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

632292:CALHY RS00410
gene id: 632292:CALHY_RS00410
uniprot id: E4Q9W9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS08030
gene id: 632292:CALHY_RS08030
uniprot id: E4QBT4
names: Similarity
messages: Belongs to the UPF0473 family.

632292:CALHY RS10465
gene id: 632292:CALHY_RS10465
uniprot id: E4QEF8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

632292:CALHY RS05120
gene id: 632292:CALHY_RS05120
uniprot id: E4Q829
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

632292:CALHY RS06365
gene id: 632292:CALHY_RS06365
uniprot id: E4Q9K0
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS12485
gene id: 632292:CALHY_RS12485
uniprot id: E4Q9Q6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

632292:CALHY RS03255
gene id: 632292:CALHY_RS03255
uniprot id: E4QD85
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

632292:CALHY RS09860
gene id: 632292:CALHY_RS09860
uniprot id: E4QDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

632292:CALHY RS07210
gene id: 632292:CALHY_RS07210
uniprot id: E4QAW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

632292:CALHY RS00755
gene id: 632292:CALHY_RS00755
uniprot id: E4QA35
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS07260
gene id: 632292:CALHY_RS07260
uniprot id: E4QAX0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

632292:CALHY RS07565
gene id: 632292:CALHY_RS07565
uniprot id: E4QBB5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

632292:CALHY RS08195
gene id: 632292:CALHY_RS08195
uniprot id: E4QC41
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

632292:CALHY RS11585
gene id: 632292:CALHY_RS11585
uniprot id: E4Q8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

632292:CALHY RS00710
gene id: 632292:CALHY_RS00710
uniprot id: E4QA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS12175
gene id: 632292:CALHY_RS12175
uniprot id: E4Q951
names: Similarity
messages: Belongs to the PspA/IM30 family.

632292:CALHY RS07055
gene id: 632292:CALHY_RS07055
uniprot id: E4QAS7
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS09815
gene id: 632292:CALHY_RS09815
uniprot id: E4QDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

632292:CALHY RS06115
gene id: 632292:CALHY_RS06115
uniprot id: E4Q908
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

632292:CALHY RS07205
gene id: 632292:CALHY_RS07205
uniprot id: E4QAV9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

632292:CALHY RS03220
gene id: 632292:CALHY_RS03220
uniprot id: E4QD78
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

632292:CALHY RS06355
gene id: 632292:CALHY_RS06355
uniprot id: E4Q9J8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS08950
gene id: 632292:CALHY_RS08950
uniprot id: E4QCY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS05995
gene id: 632292:CALHY_RS05995
uniprot id: E4Q8Y7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

632292:CALHY RS08015
gene id: 632292:CALHY_RS08015
uniprot id: E4QBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

632292:CALHY RS03555
gene id: 632292:CALHY_RS03555
uniprot id: E4QDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05020
gene id: 632292:CALHY_RS05020
uniprot id: E4Q808
names: Similarity
messages: Belongs to the phosphohexose mutase family.

632292:CALHY RS12860
gene id: 632292:CALHY_RS12860
uniprot id: E4QAC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

632292:CALHY RS12270
gene id: 632292:CALHY_RS12270
uniprot id: E4Q969
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

632292:CALHY RS09180
gene id: 632292:CALHY_RS09180
uniprot id: E4QD34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS07615
gene id: 632292:CALHY_RS07615
uniprot id: E4QBC5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

632292:CALHY RS04170
gene id: 632292:CALHY_RS04170
uniprot id: E4QE66
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

632292:CALHY RS06370
gene id: 632292:CALHY_RS06370
uniprot id: E4Q9K1
names: Similarity
messages: Belongs to the UPF0111 family.

632292:CALHY RS10280
gene id: 632292:CALHY_RS10280
uniprot id: E4QEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

632292:CALHY RS08935
gene id: 632292:CALHY_RS08935
uniprot id: E4QCY5
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

632292:CALHY RS01380
gene id: 632292:CALHY_RS01380
uniprot id: E4QB46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

632292:CALHY RS06390
gene id: 632292:CALHY_RS06390
uniprot id: E4Q9K4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

632292:CALHY RS03395
gene id: 632292:CALHY_RS03395
uniprot id: E4QDB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

632292:CALHY RS00295
gene id: 632292:CALHY_RS00295
uniprot id: E4Q9F0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS10245
gene id: 632292:CALHY_RS10245
uniprot id: E4QEB3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

632292:CALHY RS04175
gene id: 632292:CALHY_RS04175
uniprot id: E4QE67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

632292:CALHY RS12675
gene id: 632292:CALHY_RS12675
uniprot id: E4Q9U3
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS12245
gene id: 632292:CALHY_RS12245
uniprot id: E4Q964
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

632292:CALHY RS05605
gene id: 632292:CALHY_RS05605
uniprot id: E4Q8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

632292:CALHY RS03600
gene id: 632292:CALHY_RS03600
uniprot id: E4QDM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

632292:CALHY RS10565
gene id: 632292:CALHY_RS10565
uniprot id: E4Q7F0
names: Function
names: Similarity
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

632292:CALHY RS00815
gene id: 632292:CALHY_RS00815
uniprot id: E4QAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

632292:CALHY RS11280
gene id: 632292:CALHY_RS11280
uniprot id: E4Q888
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

632292:CALHY RS08840
gene id: 632292:CALHY_RS08840
uniprot id: E4QCP3
names: Similarity
messages: Belongs to the CinA family.

632292:CALHY RS08340
gene id: 632292:CALHY_RS08340
uniprot id: E4QC70
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

632292:CALHY RS04430
gene id: 632292:CALHY_RS04430
uniprot id: E4Q795
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

632292:CALHY RS12950
gene id: 632292:CALHY_RS12950
uniprot id: E4QAE7
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

632292:CALHY RS03150
gene id: 632292:CALHY_RS03150
uniprot id: E4QD64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

632292:CALHY RS07805
gene id: 632292:CALHY_RS07805
uniprot id: E4QBN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

632292:CALHY RS01085
gene id: 632292:CALHY_RS01085
uniprot id: E4QAP6
names: Subcellular Location Annotation
messages: Membrane

632292:CALHY RS01370
gene id: 632292:CALHY_RS01370
uniprot id: E4QB44
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

632292:CALHY RS11910
gene id: 632292:CALHY_RS11910
uniprot id: E4Q8S4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

632292:CALHY RS00665
gene id: 632292:CALHY_RS00665
uniprot id: E4QA20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

632292:CALHY RS10445
gene id: 632292:CALHY_RS10445
uniprot id: E4QEF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05170
gene id: 632292:CALHY_RS05170
uniprot id: E4Q839
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

632292:CALHY RS06010
gene id: 632292:CALHY_RS06010
uniprot id: E4Q8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

632292:CALHY RS06095
gene id: 632292:CALHY_RS06095
uniprot id: E4Q904
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

632292:CALHY RS06645
gene id: 632292:CALHY_RS06645
uniprot id: E4QA54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

632292:CALHY RS04880
gene id: 632292:CALHY_RS04880
uniprot id: E4Q7Q8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

632292:CALHY RS07745
gene id: 632292:CALHY_RS07745
uniprot id: E4QBE9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

632292:CALHY RS07910
gene id: 632292:CALHY_RS07910
uniprot id: E4QBQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

632292:CALHY RS11515
gene id: 632292:CALHY_RS11515
uniprot id: E4Q8C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632292:CALHY RS00655
gene id: 632292:CALHY_RS00655
uniprot id: E4QA18
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

632292:CALHY RS06655
gene id: 632292:CALHY_RS06655
uniprot id: E4QA56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

632292:CALHY RS04925
gene id: 632292:CALHY_RS04925
uniprot id: E4Q7R7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632292:CALHY RS10870
gene id: 632292:CALHY_RS10870
uniprot id: E4Q7T6
names: Similarity
messages: Belongs to the P(II) protein family.

632292:CALHY RS09130
gene id: 632292:CALHY_RS09130
uniprot id: E4QD24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

632292:CALHY RS00680
gene id: 632292:CALHY_RS00680
uniprot id: E4QA23
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

632292:CALHY RS10145
gene id: 632292:CALHY_RS10145
uniprot id: E4QE93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

632292:CALHY RS04700
gene id: 632292:CALHY_RS04700
uniprot id: E4Q7M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

632292:CALHY RS10035
gene id: 632292:CALHY_RS10035
uniprot id: E4QDZ9
names: Similarity
messages: Belongs to the RecJ family.

632292:CALHY RS12745
gene id: 632292:CALHY_RS12745
uniprot id: E4Q9V6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

632292:CALHY RS08125
gene id: 632292:CALHY_RS08125
uniprot id: E4QBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

632292:CALHY RS04705
gene id: 632292:CALHY_RS04705
uniprot id: E4Q7M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

632292:CALHY RS03215
gene id: 632292:CALHY_RS03215
uniprot id: E4QD77
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

632292:CALHY RS08740
gene id: 632292:CALHY_RS08740
uniprot id: E4QCM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

632292:CALHY RS01035
gene id: 632292:CALHY_RS01035
uniprot id: E4QAN6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

632292:CALHY RS01445
gene id: 632292:CALHY_RS01445
uniprot id: E4QB55
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

632292:CALHY RS09185
gene id: 632292:CALHY_RS09185
uniprot id: E4QD35
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

632292:CALHY RS10630
gene id: 632292:CALHY_RS10630
uniprot id: E4Q7G2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

632292:CALHY RS05175
gene id: 632292:CALHY_RS05175
uniprot id: E4Q840
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

632292:CALHY RS09885
gene id: 632292:CALHY_RS09885
uniprot id: E4QDW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS03665
gene id: 632292:CALHY_RS03665
uniprot id: E4QDP2
names: Similarity
messages: Belongs to the glutamate synthase family.

632292:CALHY RS03590
gene id: 632292:CALHY_RS03590
uniprot id: E4QDM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

632292:CALHY RS07835
gene id: 632292:CALHY_RS07835
uniprot id: E4QBP4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

632292:CALHY RS03405
gene id: 632292:CALHY_RS03405
uniprot id: E4QDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS05685
gene id: 632292:CALHY_RS05685
uniprot id: E4Q8K0
names: Similarity
messages: Belongs to the EamA transporter family.

632292:CALHY RS00540
gene id: 632292:CALHY_RS00540
uniprot id: E4Q9Z5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

632292:CALHY RS08745
gene id: 632292:CALHY_RS08745
uniprot id: E4QCM4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

632292:CALHY RS09220
gene id: 632292:CALHY_RS09220
uniprot id: E4QD40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

632292:CALHY RS06860
gene id: 632292:CALHY_RS06860
uniprot id: E4QA95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

632292:CALHY RS11310
gene id: 632292:CALHY_RS11310
uniprot id: E4Q894
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS13240
gene id: 632292:CALHY_RS13240
uniprot id: E4QB04
names: Similarity
messages: Belongs to the GerABKA family.

632292:CALHY RS07740
gene id: 632292:CALHY_RS07740
uniprot id: E4QBE8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

632292:CALHY RS06890
gene id: 632292:CALHY_RS06890
uniprot id: E4QAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

632292:CALHY RS07680
gene id: 632292:CALHY_RS07680
uniprot id: E4QBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

632292:CALHY RS09620
gene id: 632292:CALHY_RS09620
uniprot id: E4QDJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

632292:CALHY RS00275
gene id: 632292:CALHY_RS00275
uniprot id: E4Q9E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

632292:CALHY RS06875
gene id: 632292:CALHY_RS06875
uniprot id: E4QA98
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

632292:CALHY RS00715
gene id: 632292:CALHY_RS00715
uniprot id: E4QA29
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.