61858:DV706 RS15145
gene id: 61858:DV706_RS15145
uniprot id: A0A4D6HQ30
names: Subcellular Location Annotation
messages: Cell membrane

61858:DV706 RS05080
gene id: 61858:DV706_RS05080
uniprot id: A0A4D6HJE4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

61858:DV706 RS13605
gene id: 61858:DV706_RS13605
uniprot id: A0A4D6HRT2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

61858:DV706 RS11405
gene id: 61858:DV706_RS11405
uniprot id: A0A4D6HQT7
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS13675
gene id: 61858:DV706_RS13675
uniprot id: A0A4D6HPE9
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

61858:DV706 RS10810
gene id: 61858:DV706_RS10810
uniprot id: A0A4D6HNV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

61858:DV706 RS11585
gene id: 61858:DV706_RS11585
uniprot id: A0A4D6HMM2
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

61858:DV706 RS14845
gene id: 61858:DV706_RS14845
uniprot id: A0A4D6HQB4
names: Similarity
messages: Belongs to the isochorismate synthase family.

61858:DV706 RS07975
gene id: 61858:DV706_RS07975
uniprot id: A0A4D6HP95
names: Subcellular Location Annotation
messages: Nucleus

61858:DV706 RS20150
gene id: 61858:DV706_RS20150
uniprot id: A0A4D6HTL5
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS05570
gene id: 61858:DV706_RS05570
uniprot id: A0A4D6HJP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

61858:DV706 RS21180
gene id: 61858:DV706_RS21180
uniprot id: A0A4D6HU98
names: Similarity
messages: Belongs to the asparaginase 1 family.

61858:DV706 RS00690
gene id: 61858:DV706_RS00690
uniprot id: A0A4D6HHV3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

61858:DV706 RS01230
gene id: 61858:DV706_RS01230
uniprot id: A0A4D6HI82
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS14935
gene id: 61858:DV706_RS14935
uniprot id: A0A4D6HRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

61858:DV706 RS13650
gene id: 61858:DV706_RS13650
uniprot id: A0A4D6HQE9
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

61858:DV706 RS04140
gene id: 61858:DV706_RS04140
uniprot id: A0A4D6HIE3
names: Function
messages: Part of a potassium transport system.

61858:DV706 RS01440
gene id: 61858:DV706_RS01440
uniprot id: A0A4D6HGL1
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

61858:DV706 RS09470
gene id: 61858:DV706_RS09470
uniprot id: A0A4D6HPW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

61858:DV706 RS10260
gene id: 61858:DV706_RS10260
uniprot id: A0A4D6HQ87
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS08810
gene id: 61858:DV706_RS08810
uniprot id: A0A4D6HMZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

61858:DV706 RS00630
gene id: 61858:DV706_RS00630
uniprot id: A0A4D6HHU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

61858:DV706 RS02350
gene id: 61858:DV706_RS02350
uniprot id: A0A4D6HHH8
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

61858:DV706 RS12555
gene id: 61858:DV706_RS12555
uniprot id: A0A4D6HM57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

61858:DV706 RS11765
gene id: 61858:DV706_RS11765
uniprot id: A0A4D6HMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

61858:DV706 RS16715
gene id: 61858:DV706_RS16715
uniprot id: A0A4D6HR29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS02540
gene id: 61858:DV706_RS02540
uniprot id: A0A4D6HIL1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

61858:DV706 RS03695
gene id: 61858:DV706_RS03695
uniprot id: A0A4D6HK99
names: Similarity
messages: Belongs to the SCO1/2 family.

61858:DV706 RS08395
gene id: 61858:DV706_RS08395
uniprot id: A0A4D6HQW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS16465
gene id: 61858:DV706_RS16465
uniprot id: A0A4D6HH03
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

61858:DV706 RS05465
gene id: 61858:DV706_RS05465
uniprot id: A0A4D6HPE6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

61858:DV706 RS05560
gene id: 61858:DV706_RS05560
uniprot id: A0A4D6HLA7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

61858:DV706 RS15645
gene id: 61858:DV706_RS15645
uniprot id: A0A4D6HQ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

61858:DV706 RS17195
gene id: 61858:DV706_RS17195
uniprot id: A0A4D6HRX9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61858:DV706 RS03450
gene id: 61858:DV706_RS03450
uniprot id: A0A4D6HKM2
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

61858:DV706 RS07155
gene id: 61858:DV706_RS07155
uniprot id: A0A4D6HKK4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

61858:DV706 RS01875
gene id: 61858:DV706_RS01875
uniprot id: A0A4D6HJ92
names: Subcellular Location Annotation
messages: Cytoplasm

61858:DV706 RS21270
gene id: 61858:DV706_RS21270
uniprot id: A0A4D6HV85
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS00810
gene id: 61858:DV706_RS00810
uniprot id: A0A4D6HIY4
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

61858:DV706 RS09130
gene id: 61858:DV706_RS09130
uniprot id: A0A4D6HN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS19305
gene id: 61858:DV706_RS19305
uniprot id: A0A4D6HUV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS11955
gene id: 61858:DV706_RS11955
uniprot id: A0A4D6HNT2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

61858:DV706 RS08085
gene id: 61858:DV706_RS08085
uniprot id: A0A4D6HMQ3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

61858:DV706 RS02310
gene id: 61858:DV706_RS02310
uniprot id: A0A4D6HIH0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03220
gene id: 61858:DV706_RS03220
uniprot id: A0A4D6HHX5
names: Similarity
messages: Belongs to the TrpC family.

61858:DV706 RS04245
gene id: 61858:DV706_RS04245
uniprot id: A0A4D6HIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

61858:DV706 RS06540
gene id: 61858:DV706_RS06540
uniprot id: A0A4D6HMD7
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07385
gene id: 61858:DV706_RS07385
uniprot id: A0A4D6HLG0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

61858:DV706 RS00490
gene id: 61858:DV706_RS00490
uniprot id: A0A4D6HH39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

61858:DV706 RS16670
gene id: 61858:DV706_RS16670
uniprot id: A0A4D6HRN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS00450
gene id: 61858:DV706_RS00450
uniprot id: A0A4D6HS16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS16800
gene id: 61858:DV706_RS16800
uniprot id: A0A4D6HGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

61858:DV706 RS07050
gene id: 61858:DV706_RS07050
uniprot id: A0A4D6HMM4
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

61858:DV706 RS08145
gene id: 61858:DV706_RS08145
uniprot id: A0A4D6HMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

61858:DV706 RS04760
gene id: 61858:DV706_RS04760
uniprot id: A0A4D6HJV5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

61858:DV706 RS11600
gene id: 61858:DV706_RS11600
uniprot id: A0A4D6HPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

61858:DV706 RS16990
gene id: 61858:DV706_RS16990
uniprot id: A0A4D6HIA6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS07665
gene id: 61858:DV706_RS07665
uniprot id: A0A4D6HKJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

61858:DV706 RS15010
gene id: 61858:DV706_RS15010
uniprot id: A0A4D6HQE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS12895
gene id: 61858:DV706_RS12895
uniprot id: A0A4D6HMY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

61858:DV706 RS01220
gene id: 61858:DV706_RS01220
uniprot id: A0A4D6HPM2
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10240
gene id: 61858:DV706_RS10240
uniprot id: A0A4D6HLT6
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

61858:DV706 RS08015
gene id: 61858:DV706_RS08015
uniprot id: A0A4D6HJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

61858:DV706 RS10290
gene id: 61858:DV706_RS10290
uniprot id: A0A4D6HLU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61858:DV706 RS06240
gene id: 61858:DV706_RS06240
uniprot id: A0A4D6HLL0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

61858:DV706 RS12985
gene id: 61858:DV706_RS12985
uniprot id: A0A4D6HRK8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

61858:DV706 RS16745
gene id: 61858:DV706_RS16745
uniprot id: A0A4D6HSK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

61858:DV706 RS12225
gene id: 61858:DV706_RS12225
uniprot id: A0A4D6HLX7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS08380
gene id: 61858:DV706_RS08380
uniprot id: A0A4D6HN79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS15300
gene id: 61858:DV706_RS15300
uniprot id: A0A4D6HQX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS15860
gene id: 61858:DV706_RS15860
uniprot id: A0A4D6HQ56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS07080
gene id: 61858:DV706_RS07080
uniprot id: A0A4D6HNR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

61858:DV706 RS16170
gene id: 61858:DV706_RS16170
uniprot id: A0A4D6HI13
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

61858:DV706 RS12410
gene id: 61858:DV706_RS12410
uniprot id: A0A4D6HPQ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

61858:DV706 RS01020
gene id: 61858:DV706_RS01020
uniprot id: A0A4D6HQC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS14810
gene id: 61858:DV706_RS14810
uniprot id: A0A4D6HQP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

61858:DV706 RS17760
gene id: 61858:DV706_RS17760
uniprot id: A0A4D6HS61
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS16510
gene id: 61858:DV706_RS16510
uniprot id: A0A4D6HHU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

61858:DV706 RS10160
gene id: 61858:DV706_RS10160
uniprot id: A0A4D6HLI7
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

61858:DV706 RS17750
gene id: 61858:DV706_RS17750
uniprot id: A0A4D6HQV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS17550
gene id: 61858:DV706_RS17550
uniprot id: A0A4D6HSE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

61858:DV706 RS17395
gene id: 61858:DV706_RS17395
uniprot id: A0A4D6HRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

61858:DV706 RS20160
gene id: 61858:DV706_RS20160
uniprot id: A0A4D6HSM4
names: Similarity
messages: Belongs to the PrpD family.

61858:DV706 RS07245
gene id: 61858:DV706_RS07245
uniprot id: A0A4D6HM11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS07565
gene id: 61858:DV706_RS07565
uniprot id: A0A4D6HM70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

61858:DV706 RS15610
gene id: 61858:DV706_RS15610
uniprot id: A0A4D6HRN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS15125
gene id: 61858:DV706_RS15125
uniprot id: A0A4D6HSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

61858:DV706 RS06960
gene id: 61858:DV706_RS06960
uniprot id: A0A4D6HNN9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

61858:DV706 RS04330
gene id: 61858:DV706_RS04330
uniprot id: A0A4D6HHX4
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

61858:DV706 RS03195
gene id: 61858:DV706_RS03195
uniprot id: A0A4D6HJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

61858:DV706 RS09495
gene id: 61858:DV706_RS09495
uniprot id: A0A4D6HNQ2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

61858:DV706 RS01100
gene id: 61858:DV706_RS01100
uniprot id: A0A4D6HGV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

61858:DV706 RS09195
gene id: 61858:DV706_RS09195
uniprot id: A0A4D6HLF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS03365
gene id: 61858:DV706_RS03365
uniprot id: A0A4D6HLK4
names: Subunit
messages: Homodimer.

61858:DV706 RS05410
gene id: 61858:DV706_RS05410
uniprot id: A0A4D6HLN0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

61858:DV706 RS08665
gene id: 61858:DV706_RS08665
uniprot id: A0A4D6HK02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS17610
gene id: 61858:DV706_RS17610
uniprot id: A0A4D6HSF5
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS20550
gene id: 61858:DV706_RS20550
uniprot id: A0A4D6HTV2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

61858:DV706 RS00565
gene id: 61858:DV706_RS00565
uniprot id: A0A4D6HG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

61858:DV706 RS17615
gene id: 61858:DV706_RS17615
uniprot id: A0A4D6HSX5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

61858:DV706 RS03285
gene id: 61858:DV706_RS03285
uniprot id: A0A4D6HJ00
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

61858:DV706 RS03385
gene id: 61858:DV706_RS03385
uniprot id: A0A4D6HIK4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

61858:DV706 RS00435
gene id: 61858:DV706_RS00435
uniprot id: A0A4D6HGD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

61858:DV706 RS01825
gene id: 61858:DV706_RS01825
uniprot id: A0A4D6HJ79
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

61858:DV706 RS06125
gene id: 61858:DV706_RS06125
uniprot id: A0A4D6HJH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

61858:DV706 RS00590
gene id: 61858:DV706_RS00590
uniprot id: A0A4D6HQ59
names: Subcellular Location Annotation
messages: Cytoplasm

61858:DV706 RS05400
gene id: 61858:DV706_RS05400
uniprot id: A0A4D6HJL0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

61858:DV706 RS16550
gene id: 61858:DV706_RS16550
uniprot id: A0A4D6HQ59
names: Subcellular Location Annotation
messages: Cytoplasm

61858:DV706 RS14590
gene id: 61858:DV706_RS14590
uniprot id: A0A4D6HP12
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

61858:DV706 RS11430
gene id: 61858:DV706_RS11430
uniprot id: A0A4D6HN74
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS17215
gene id: 61858:DV706_RS17215
uniprot id: A0A4D6HSA3
names: Similarity
messages: Belongs to the AOR/FOR family.

61858:DV706 RS12475
gene id: 61858:DV706_RS12475
uniprot id: A0A4D6HPR8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

61858:DV706 RS16705
gene id: 61858:DV706_RS16705
uniprot id: A0A4D6HGD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

61858:DV706 RS05460
gene id: 61858:DV706_RS05460
uniprot id: A0A4D6HLP5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

61858:DV706 RS02420
gene id: 61858:DV706_RS02420
uniprot id: A0A4D6HHI8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03075
gene id: 61858:DV706_RS03075
uniprot id: A0A4D6HQN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

61858:DV706 RS04375
gene id: 61858:DV706_RS04375
uniprot id: A0A4D6HNQ0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS15235
gene id: 61858:DV706_RS15235
uniprot id: A0A4D6HSD7
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

61858:DV706 RS15185
gene id: 61858:DV706_RS15185
uniprot id: A0A4D6HQV1
names: Function
messages: Part of a potassium transport system.

61858:DV706 RS13490
gene id: 61858:DV706_RS13490
uniprot id: A0A4D6HRR9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS09995
gene id: 61858:DV706_RS09995
uniprot id: A0A4D6HMG8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS16645
gene id: 61858:DV706_RS16645
uniprot id: A0A4D6HSH8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

61858:DV706 RS04565
gene id: 61858:DV706_RS04565
uniprot id: A0A4D6HJV8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

61858:DV706 RS09840
gene id: 61858:DV706_RS09840
uniprot id: A0A4D6HRU3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

61858:DV706 RS16290
gene id: 61858:DV706_RS16290
uniprot id: A0A4D6HRH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

61858:DV706 RS02320
gene id: 61858:DV706_RS02320
uniprot id: A0A4D6HHS6
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS00820
gene id: 61858:DV706_RS00820
uniprot id: A0A4D6HQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

61858:DV706 RS00100
gene id: 61858:DV706_RS00100
uniprot id: A0A4D6HJ13
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05160
gene id: 61858:DV706_RS05160
uniprot id: A0A4D6HK60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS07745
gene id: 61858:DV706_RS07745
uniprot id: A0A4D6HMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

61858:DV706 RS07260
gene id: 61858:DV706_RS07260
uniprot id: A0A4D6HK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS16660
gene id: 61858:DV706_RS16660
uniprot id: A0A4D6HQ85
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

61858:DV706 RS18560
gene id: 61858:DV706_RS18560
uniprot id: A0A4D6HSV8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

61858:DV706 RS03975
gene id: 61858:DV706_RS03975
uniprot id: A0A4D6HKH4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

61858:DV706 RS08565
gene id: 61858:DV706_RS08565
uniprot id: A0A4D6HL59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

61858:DV706 RS08010
gene id: 61858:DV706_RS08010
uniprot id: A0A4D6HKQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

61858:DV706 RS12740
gene id: 61858:DV706_RS12740
uniprot id: A0A4D6HM84
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS00550
gene id: 61858:DV706_RS00550
uniprot id: A0A4D6HRZ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61858:DV706 RS07735
gene id: 61858:DV706_RS07735
uniprot id: A0A4D6HP54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS15100
gene id: 61858:DV706_RS15100
uniprot id: A0A4D6HRD3
names: Similarity
messages: Belongs to the FUN14 family.

61858:DV706 RS09115
gene id: 61858:DV706_RS09115
uniprot id: A0A4D6HK85
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05095
gene id: 61858:DV706_RS05095
uniprot id: A0A4D6HR38
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS13350
gene id: 61858:DV706_RS13350
uniprot id: A0A4D6HNI7
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

61858:DV706 RS00920
gene id: 61858:DV706_RS00920
uniprot id: A0A4D6HSI8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

61858:DV706 RS21230
gene id: 61858:DV706_RS21230
uniprot id: A0A4D6HVJ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS17755
gene id: 61858:DV706_RS17755
uniprot id: A0A4D6HRL8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06885
gene id: 61858:DV706_RS06885
uniprot id: A0A4D6HP77
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

61858:DV706 RS05105
gene id: 61858:DV706_RS05105
uniprot id: A0A4D6HIC1
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

61858:DV706 RS06820
gene id: 61858:DV706_RS06820
uniprot id: A0A4D6HKZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

61858:DV706 RS02140
gene id: 61858:DV706_RS02140
uniprot id: A0A4D6HKW6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

61858:DV706 RS21220
gene id: 61858:DV706_RS21220
uniprot id: A0A4D6HV70
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

61858:DV706 RS00465
gene id: 61858:DV706_RS00465
uniprot id: A0A4D6HSS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS01545
gene id: 61858:DV706_RS01545
uniprot id: A0A4D6HHR7
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06325
gene id: 61858:DV706_RS06325
uniprot id: A0A4D6HKN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

61858:DV706 RS11025
gene id: 61858:DV706_RS11025
uniprot id: A0A4D6HP01
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

61858:DV706 RS00305
gene id: 61858:DV706_RS00305
uniprot id: A0A4D6HJX8
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

61858:DV706 RS10025
gene id: 61858:DV706_RS10025
uniprot id: A0A4D6HND4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

61858:DV706 RS08765
gene id: 61858:DV706_RS08765
uniprot id: A0A4D6HRS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

61858:DV706 RS06775
gene id: 61858:DV706_RS06775
uniprot id: A0A4D6HMH9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS09075
gene id: 61858:DV706_RS09075
uniprot id: A0A4D6HMX6
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

61858:DV706 RS14355
gene id: 61858:DV706_RS14355
uniprot id: A0A4D6HPQ1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

61858:DV706 RS00675
gene id: 61858:DV706_RS00675
uniprot id: A0A4D6HH03
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

61858:DV706 RS16615
gene id: 61858:DV706_RS16615
uniprot id: A0A4D6HQZ8
names: Similarity
messages: Belongs to the peptidase S8 family.

61858:DV706 RS13060
gene id: 61858:DV706_RS13060
uniprot id: A0A4D6HNE0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05030
gene id: 61858:DV706_RS05030
uniprot id: A0A4D6HLE1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS08045
gene id: 61858:DV706_RS08045
uniprot id: A0A4D6HKZ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

61858:DV706 RS06080
gene id: 61858:DV706_RS06080
uniprot id: A0A4D6HKK3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

61858:DV706 RS07705
gene id: 61858:DV706_RS07705
uniprot id: A0A4D6HLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

61858:DV706 RS12510
gene id: 61858:DV706_RS12510
uniprot id: A0A4D6HP51
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS11535
gene id: 61858:DV706_RS11535
uniprot id: A0A4D6HML2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

61858:DV706 RS16820
gene id: 61858:DV706_RS16820
uniprot id: A0A4D6HGB7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

61858:DV706 RS16730
gene id: 61858:DV706_RS16730
uniprot id: A0A4D6HG62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

61858:DV706 RS14535
gene id: 61858:DV706_RS14535
uniprot id: A0A4D6HP07
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS19485
gene id: 61858:DV706_RS19485
uniprot id: A0A4D6HV55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

61858:DV706 RS06360
gene id: 61858:DV706_RS06360
uniprot id: A0A4D6HLT3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

61858:DV706 RS15905
gene id: 61858:DV706_RS15905
uniprot id: A0A4D6HJ60
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05440
gene id: 61858:DV706_RS05440
uniprot id: A0A4D6HL90
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

61858:DV706 RS16650
gene id: 61858:DV706_RS16650
uniprot id: A0A4D6HH39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

61858:DV706 RS16540
gene id: 61858:DV706_RS16540
uniprot id: A0A4D6HTI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS03475
gene id: 61858:DV706_RS03475
uniprot id: A0A4D6HLM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS13770
gene id: 61858:DV706_RS13770
uniprot id: A0A4D6HQ88
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

61858:DV706 RS16120
gene id: 61858:DV706_RS16120
uniprot id: A0A4D6HQC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS10385
gene id: 61858:DV706_RS10385
uniprot id: A0A4D6HQA5
names: Similarity
messages: Belongs to the UPF0173 family.

61858:DV706 RS03260
gene id: 61858:DV706_RS03260
uniprot id: A0A4D6HK33
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

61858:DV706 RS17445
gene id: 61858:DV706_RS17445
uniprot id: A0A4D6HQP1
names: Similarity
messages: Belongs to the Dps family.

61858:DV706 RS10750
gene id: 61858:DV706_RS10750
uniprot id: A0A4D6HL03
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

61858:DV706 RS10805
gene id: 61858:DV706_RS10805
uniprot id: A0A4D6HN44
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS08640
gene id: 61858:DV706_RS08640
uniprot id: A0A4D6HKR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

61858:DV706 RS03625
gene id: 61858:DV706_RS03625
uniprot id: A0A4D6HKA5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

61858:DV706 RS20135
gene id: 61858:DV706_RS20135
uniprot id: A0A4D6HSF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS18690
gene id: 61858:DV706_RS18690
uniprot id: A0A4D6HTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

61858:DV706 RS16525
gene id: 61858:DV706_RS16525
uniprot id: A0A4D6HGZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

61858:DV706 RS00265
gene id: 61858:DV706_RS00265
uniprot id: A0A4D6HGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS08890
gene id: 61858:DV706_RS08890
uniprot id: A0A4D6HL41
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

61858:DV706 RS07465
gene id: 61858:DV706_RS07465
uniprot id: A0A4D6HME9
names: Similarity
messages: Belongs to the selenium-binding protein family.

61858:DV706 RS02365
gene id: 61858:DV706_RS02365
uniprot id: A0A4D6HII0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

61858:DV706 RS18120
gene id: 61858:DV706_RS18120
uniprot id: A0A4D6HTN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS04405
gene id: 61858:DV706_RS04405
uniprot id: A0A4D6HKP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS09430
gene id: 61858:DV706_RS09430
uniprot id: A0A4D6HNP1
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS15805
gene id: 61858:DV706_RS15805
uniprot id: A0A4D6HIA3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

61858:DV706 RS12800
gene id: 61858:DV706_RS12800
uniprot id: A0A4D6HRE5
names: Similarity
messages: Belongs to the UPF0212 family.

61858:DV706 RS12285
gene id: 61858:DV706_RS12285
uniprot id: A0A4D6HR22
names: Similarity
messages: Belongs to the peptidase M24B family.

61858:DV706 RS04100
gene id: 61858:DV706_RS04100
uniprot id: A0A4D6HJG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

61858:DV706 RS07630
gene id: 61858:DV706_RS07630
uniprot id: A0A4D6HP34
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS14660
gene id: 61858:DV706_RS14660
uniprot id: A0A4D6HP19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

61858:DV706 RS10985
gene id: 61858:DV706_RS10985
uniprot id: A0A4D6HQL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

61858:DV706 RS01480
gene id: 61858:DV706_RS01480
uniprot id: A0A4D6HHQ8
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

61858:DV706 RS00150
gene id: 61858:DV706_RS00150
uniprot id: A0A4D6HIA6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS03850
gene id: 61858:DV706_RS03850
uniprot id: A0A4D6HIJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61858:DV706 RS19665
gene id: 61858:DV706_RS19665
uniprot id: A0A4D6HUC1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS03510
gene id: 61858:DV706_RS03510
uniprot id: A0A4D6HHF6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

61858:DV706 RS00495
gene id: 61858:DV706_RS00495
uniprot id: A0A4D6HSH8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

61858:DV706 RS20810
gene id: 61858:DV706_RS20810
uniprot id: A0A4D6HSW7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS14645
gene id: 61858:DV706_RS14645
uniprot id: A0A4D6HQM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS11650
gene id: 61858:DV706_RS11650
uniprot id: A0A4D6HPV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS19640
gene id: 61858:DV706_RS19640
uniprot id: A0A4D6HUL2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

61858:DV706 RS13020
gene id: 61858:DV706_RS13020
uniprot id: A0A4D6HMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

61858:DV706 RS19585
gene id: 61858:DV706_RS19585
uniprot id: A0A4D6HUK3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS08170
gene id: 61858:DV706_RS08170
uniprot id: A0A4D6HN54
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.

61858:DV706 RS04620
gene id: 61858:DV706_RS04620
uniprot id: A0A4D6HI30
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

61858:DV706 RS05615
gene id: 61858:DV706_RS05615
uniprot id: A0A4D6HJ89
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

61858:DV706 RS18830
gene id: 61858:DV706_RS18830
uniprot id: A0A4D6HS54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

61858:DV706 RS10640
gene id: 61858:DV706_RS10640
uniprot id: A0A4D6HPB0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

61858:DV706 RS06655
gene id: 61858:DV706_RS06655
uniprot id: A0A4D6HMF8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

61858:DV706 RS12655
gene id: 61858:DV706_RS12655
uniprot id: A0A4D6HMU8
names: Similarity
messages: Belongs to the CutA family.

61858:DV706 RS16435
gene id: 61858:DV706_RS16435
uniprot id: A0A4D6HK40
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

61858:DV706 RS20100
gene id: 61858:DV706_RS20100
uniprot id: A0A4D6HUM3
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS14850
gene id: 61858:DV706_RS14850
uniprot id: A0A4D6HQX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

61858:DV706 RS08650
gene id: 61858:DV706_RS08650
uniprot id: A0A4D6HLT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

61858:DV706 RS11160
gene id: 61858:DV706_RS11160
uniprot id: A0A4D6HPL0
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

61858:DV706 RS05765
gene id: 61858:DV706_RS05765
uniprot id: A0A4D6HLC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS16325
gene id: 61858:DV706_RS16325
uniprot id: A0A4D6HK62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

61858:DV706 RS16710
gene id: 61858:DV706_RS16710
uniprot id: A0A4D6HIF1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

61858:DV706 RS05385
gene id: 61858:DV706_RS05385
uniprot id: A0A4D6HMM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS10680
gene id: 61858:DV706_RS10680
uniprot id: A0A4D6HM37
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS12885
gene id: 61858:DV706_RS12885
uniprot id: A0A4D6HP22
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

61858:DV706 RS00250
gene id: 61858:DV706_RS00250
uniprot id: A0A4D6HRT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS12060
gene id: 61858:DV706_RS12060
uniprot id: A0A4D6HLU0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61858:DV706 RS08970
gene id: 61858:DV706_RS08970
uniprot id: A0A4D6HM53
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS12160
gene id: 61858:DV706_RS12160
uniprot id: A0A4D6HQ53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS20040
gene id: 61858:DV706_RS20040
uniprot id: A0A4D6HUL4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

61858:DV706 RS12040
gene id: 61858:DV706_RS12040
uniprot id: A0A4D6HRW8
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

61858:DV706 RS15255
gene id: 61858:DV706_RS15255
uniprot id: A0A4D6HQ49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

61858:DV706 RS13270
gene id: 61858:DV706_RS13270
uniprot id: A0A4D6HPI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

61858:DV706 RS06260
gene id: 61858:DV706_RS06260
uniprot id: A0A4D6HJK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

61858:DV706 RS02395
gene id: 61858:DV706_RS02395
uniprot id: A0A4D6HIS4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

61858:DV706 RS05455
gene id: 61858:DV706_RS05455
uniprot id: A0A4D6HKA0
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

61858:DV706 RS18780
gene id: 61858:DV706_RS18780
uniprot id: A0A4D6HSM5
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10510
gene id: 61858:DV706_RS10510
uniprot id: A0A4D6HNT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

61858:DV706 RS07140
gene id: 61858:DV706_RS07140
uniprot id: A0A4D6HNS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

61858:DV706 RS12310
gene id: 61858:DV706_RS12310
uniprot id: A0A4D6HN09
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

61858:DV706 RS04025
gene id: 61858:DV706_RS04025
uniprot id: A0A4D6HJM7
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS11045
gene id: 61858:DV706_RS11045
uniprot id: A0A4D6HMC2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61858:DV706 RS03335
gene id: 61858:DV706_RS03335
uniprot id: A0A4D6HJ09
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06950
gene id: 61858:DV706_RS06950
uniprot id: A0A4D6HL84
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

61858:DV706 RS11460
gene id: 61858:DV706_RS11460
uniprot id: A0A4D6HPA3
names: Similarity
messages: Belongs to the UPF0212 family.

61858:DV706 RS06025
gene id: 61858:DV706_RS06025
uniprot id: A0A4D6HKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

61858:DV706 RS12550
gene id: 61858:DV706_RS12550
uniprot id: A0A4D6HQD5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

61858:DV706 RS07335
gene id: 61858:DV706_RS07335
uniprot id: A0A4D6HM45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

61858:DV706 RS08345
gene id: 61858:DV706_RS08345
uniprot id: A0A4D6HRS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

61858:DV706 RS13050
gene id: 61858:DV706_RS13050
uniprot id: A0A4D6HPZ4
names: Similarity
messages: Belongs to the Dps family.

61858:DV706 RS17140
gene id: 61858:DV706_RS17140
uniprot id: A0A4D6HSY6
names: Similarity
messages: Belongs to the selenium-binding protein family.

61858:DV706 RS17075
gene id: 61858:DV706_RS17075
uniprot id: A0A4D6HRV9
names: Similarity
messages: Belongs to the TrpF family.

61858:DV706 RS04645
gene id: 61858:DV706_RS04645
uniprot id: A0A4D6HIQ2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

61858:DV706 RS09825
gene id: 61858:DV706_RS09825
uniprot id: A0A4D6HNF5
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

61858:DV706 RS05705
gene id: 61858:DV706_RS05705
uniprot id: A0A4D6HLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

61858:DV706 RS13515
gene id: 61858:DV706_RS13515
uniprot id: A0A4D6HPC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

61858:DV706 RS07800
gene id: 61858:DV706_RS07800
uniprot id: A0A4D6HM97
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

61858:DV706 RS12890
gene id: 61858:DV706_RS12890
uniprot id: A0A4D6HQH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS02315
gene id: 61858:DV706_RS02315
uniprot id: A0A4D6HK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

61858:DV706 RS15700
gene id: 61858:DV706_RS15700
uniprot id: A0A4D6HGL1
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

61858:DV706 RS06040
gene id: 61858:DV706_RS06040
uniprot id: A0A4D6HIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

61858:DV706 RS04560
gene id: 61858:DV706_RS04560
uniprot id: A0A4D6HI20
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

61858:DV706 RS10955
gene id: 61858:DV706_RS10955
uniprot id: A0A4D6HPH1
names: Caution
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS05840
gene id: 61858:DV706_RS05840
uniprot id: A0A4D6HLG6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

61858:DV706 RS11680
gene id: 61858:DV706_RS11680
uniprot id: A0A4D6HQZ4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

61858:DV706 RS09140
gene id: 61858:DV706_RS09140
uniprot id: A0A4D6HLE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

61858:DV706 RS10340
gene id: 61858:DV706_RS10340
uniprot id: A0A4D6HMM3
names: Subcellular Location Annotation
messages: Cytoplasm

61858:DV706 RS15195
gene id: 61858:DV706_RS15195
uniprot id: A0A4D6HQT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

61858:DV706 RS06020
gene id: 61858:DV706_RS06020
uniprot id: A0A4D6HJY0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS05745
gene id: 61858:DV706_RS05745
uniprot id: A0A4D6HLV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

61858:DV706 RS00525
gene id: 61858:DV706_RS00525
uniprot id: A0A4D6HQZ8
names: Similarity
messages: Belongs to the peptidase S8 family.

61858:DV706 RS16295
gene id: 61858:DV706_RS16295
uniprot id: A0A4D6HH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

61858:DV706 RS17985
gene id: 61858:DV706_RS17985
uniprot id: A0A4D6HQZ2
names: Similarity
messages: Belongs to the UPF0045 family.

61858:DV706 RS01495
gene id: 61858:DV706_RS01495
uniprot id: A0A4D6HQ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

61858:DV706 RS11890
gene id: 61858:DV706_RS11890
uniprot id: A0A4D6HNS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

61858:DV706 RS16405
gene id: 61858:DV706_RS16405
uniprot id: A0A4D6HH16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Belongs to the inositol monophosphatase superfamily.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS02565
gene id: 61858:DV706_RS02565
uniprot id: A0A4D6HJR4
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10355
gene id: 61858:DV706_RS10355
uniprot id: A0A4D6HKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

61858:DV706 RS16680
gene id: 61858:DV706_RS16680
uniprot id: A0A4D6HG68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

61858:DV706 RS19950
gene id: 61858:DV706_RS19950
uniprot id: A0A4D6HUC9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

61858:DV706 RS11435
gene id: 61858:DV706_RS11435
uniprot id: A0A4D6HPQ5
names: Subcellular Location Annotation
messages: Cytoplasm

61858:DV706 RS11825
gene id: 61858:DV706_RS11825
uniprot id: A0A4D6HPY4
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS04365
gene id: 61858:DV706_RS04365
uniprot id: A0A4D6HJM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS20845
gene id: 61858:DV706_RS20845
uniprot id: A0A4D6HW23
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

61858:DV706 RS20650
gene id: 61858:DV706_RS20650
uniprot id: A0A4D6HV77
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

61858:DV706 RS09620
gene id: 61858:DV706_RS09620
uniprot id: A0A4D6HN59
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS20055
gene id: 61858:DV706_RS20055
uniprot id: A0A4D6HS95
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05005
gene id: 61858:DV706_RS05005
uniprot id: A0A4D6HMF5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

61858:DV706 RS11805
gene id: 61858:DV706_RS11805
uniprot id: A0A4D6HPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

61858:DV706 RS10760
gene id: 61858:DV706_RS10760
uniprot id: A0A4D6HNU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

61858:DV706 RS09290
gene id: 61858:DV706_RS09290
uniprot id: A0A4D6HPT3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

61858:DV706 RS09710
gene id: 61858:DV706_RS09710
uniprot id: A0A4D6HMB6
names: Similarity
messages: Belongs to the citrate synthase family.

61858:DV706 RS15000
gene id: 61858:DV706_RS15000
uniprot id: A0A4D6HP16
names: Similarity
messages: Belongs to the UPF0047 family.

61858:DV706 RS15735
gene id: 61858:DV706_RS15735
uniprot id: A0A4D6HJ07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS13680
gene id: 61858:DV706_RS13680
uniprot id: A0A4D6HQU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

61858:DV706 RS15435
gene id: 61858:DV706_RS15435
uniprot id: A0A4D6HQ57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

61858:DV706 RS11790
gene id: 61858:DV706_RS11790
uniprot id: A0A4D6HNP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

61858:DV706 RS17890
gene id: 61858:DV706_RS17890
uniprot id: A0A4D6HU66
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

61858:DV706 RS15275
gene id: 61858:DV706_RS15275
uniprot id: A0A4D6HNJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

61858:DV706 RS16580
gene id: 61858:DV706_RS16580
uniprot id: A0A4D6HGY0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS08350
gene id: 61858:DV706_RS08350
uniprot id: A0A4D6HMT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

61858:DV706 RS00395
gene id: 61858:DV706_RS00395
uniprot id: A0A4D6HSK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

61858:DV706 RS07460
gene id: 61858:DV706_RS07460
uniprot id: A0A4D6HNY4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

61858:DV706 RS04170
gene id: 61858:DV706_RS04170
uniprot id: A0A4D6HHT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

61858:DV706 RS01530
gene id: 61858:DV706_RS01530
uniprot id: A0A4D6HRN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS10425
gene id: 61858:DV706_RS10425
uniprot id: A0A4D6HKV1
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

61858:DV706 RS01705
gene id: 61858:DV706_RS01705
uniprot id: A0A4D6HQ57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

61858:DV706 RS07660
gene id: 61858:DV706_RS07660
uniprot id: A0A4D6HMX1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS05035
gene id: 61858:DV706_RS05035
uniprot id: A0A4D6HJ74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS04445
gene id: 61858:DV706_RS04445
uniprot id: A0A4D6HJU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

61858:DV706 RS05880
gene id: 61858:DV706_RS05880
uniprot id: A0A4D6HLD8
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

61858:DV706 RS02345
gene id: 61858:DV706_RS02345
uniprot id: A0A4D6HJK3
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06910
gene id: 61858:DV706_RS06910
uniprot id: A0A4D6HNM8
names: Similarity
messages: Belongs to the aspartokinase family.

61858:DV706 RS15605
gene id: 61858:DV706_RS15605
uniprot id: A0A4D6HRN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS12700
gene id: 61858:DV706_RS12700
uniprot id: A0A4D6HQ18
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06805
gene id: 61858:DV706_RS06805
uniprot id: A0A4D6HM36
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS05510
gene id: 61858:DV706_RS05510
uniprot id: A0A4D6HL99
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03885
gene id: 61858:DV706_RS03885
uniprot id: A0A4D6HIT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS00530
gene id: 61858:DV706_RS00530
uniprot id: A0A4D6HIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

61858:DV706 RS13750
gene id: 61858:DV706_RS13750
uniprot id: A0A4D6HPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61858:DV706 RS12295
gene id: 61858:DV706_RS12295
uniprot id: A0A4D6HRC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61858:DV706 RS11240
gene id: 61858:DV706_RS11240
uniprot id: A0A4D6HP79
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

61858:DV706 RS02900
gene id: 61858:DV706_RS02900
uniprot id: A0A4D6HI23
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

61858:DV706 RS07740
gene id: 61858:DV706_RS07740
uniprot id: A0A4D6HPI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

61858:DV706 RS03000
gene id: 61858:DV706_RS03000
uniprot id: A0A4D6HIU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS07760
gene id: 61858:DV706_RS07760
uniprot id: C5NSJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

61858:DV706 RS00560
gene id: 61858:DV706_RS00560
uniprot id: A0A4D6HGY0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS18750
gene id: 61858:DV706_RS18750
uniprot id: A0A4D6HUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

61858:DV706 RS13660
gene id: 61858:DV706_RS13660
uniprot id: A0A4D6HQ74
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

61858:DV706 RS12525
gene id: 61858:DV706_RS12525
uniprot id: A0A4D6HPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

61858:DV706 RS06465
gene id: 61858:DV706_RS06465
uniprot id: A0A4D6HLV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

61858:DV706 RS00035
gene id: 61858:DV706_RS00035
uniprot id: A0A4D6HTT8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03215
gene id: 61858:DV706_RS03215
uniprot id: A0A4D6HK15
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

61858:DV706 RS20195
gene id: 61858:DV706_RS20195
uniprot id: A0A4D6HUS4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS07305
gene id: 61858:DV706_RS07305
uniprot id: A0A4D6HKN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS10875
gene id: 61858:DV706_RS10875
uniprot id: A0A4D6HP04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

61858:DV706 RS02225
gene id: 61858:DV706_RS02225
uniprot id: A0A4D6HHQ3
names: Similarity
messages: Belongs to the NAPRTase family.

61858:DV706 RS09125
gene id: 61858:DV706_RS09125
uniprot id: A0A4D6HPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

61858:DV706 RS11910
gene id: 61858:DV706_RS11910
uniprot id: A0A4D6HPH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS05115
gene id: 61858:DV706_RS05115
uniprot id: A0A4D6HL22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

61858:DV706 RS03160
gene id: 61858:DV706_RS03160
uniprot id: A0A4D6HHV6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

61858:DV706 RS01010
gene id: 61858:DV706_RS01010
uniprot id: A0A4D6HRN9
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS00405
gene id: 61858:DV706_RS00405
uniprot id: A0A4D6HQA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

61858:DV706 RS09740
gene id: 61858:DV706_RS09740
uniprot id: A0A4D6HMI7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

61858:DV706 RS02360
gene id: 61858:DV706_RS02360
uniprot id: A0A4D6HQ89
names: Similarity
messages: Belongs to the complex I subunit 3 family.

61858:DV706 RS01235
gene id: 61858:DV706_RS01235
uniprot id: A0A4D6HJ60
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10175
gene id: 61858:DV706_RS10175
uniprot id: A0A4D6HMJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

61858:DV706 RS16270
gene id: 61858:DV706_RS16270
uniprot id: A0A4D6HK73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

61858:DV706 RS07670
gene id: 61858:DV706_RS07670
uniprot id: A0A4D6HJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

61858:DV706 RS16520
gene id: 61858:DV706_RS16520
uniprot id: A0A4D6HQM4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

61858:DV706 RS04120
gene id: 61858:DV706_RS04120
uniprot id: A0A4D6HJP3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

61858:DV706 RS01090
gene id: 61858:DV706_RS01090
uniprot id: A0A4D6HQI9
names: Similarity
messages: Belongs to the peptidase S49 family.

61858:DV706 RS05010
gene id: 61858:DV706_RS05010
uniprot id: A0A4D6HL02
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS02990
gene id: 61858:DV706_RS02990
uniprot id: A0A4D6HHT3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

61858:DV706 RS14820
gene id: 61858:DV706_RS14820
uniprot id: A0A4D6HP41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

61858:DV706 RS16040
gene id: 61858:DV706_RS16040
uniprot id: A0A4D6HGV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

61858:DV706 RS18805
gene id: 61858:DV706_RS18805
uniprot id: A0A4D6HTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

61858:DV706 RS10780
gene id: 61858:DV706_RS10780
uniprot id: A0A4D6HM61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

61858:DV706 RS00400
gene id: 61858:DV706_RS00400
uniprot id: A0A4D6HJ63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS00615
gene id: 61858:DV706_RS00615
uniprot id: A0A4D6HGZ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

61858:DV706 RS03200
gene id: 61858:DV706_RS03200
uniprot id: A0A4D6HR12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61858:DV706 RS20120
gene id: 61858:DV706_RS20120
uniprot id: A0A4D6HUG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS09325
gene id: 61858:DV706_RS09325
uniprot id: A0A4D6HLD3
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS17275
gene id: 61858:DV706_RS17275
uniprot id: A0A4D6HR21
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

61858:DV706 RS16345
gene id: 61858:DV706_RS16345
uniprot id: A0A4D6HH30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS07645
gene id: 61858:DV706_RS07645
uniprot id: A0A4D6HRR0
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

61858:DV706 RS14965
gene id: 61858:DV706_RS14965
uniprot id: A0A4D6HQR8
names: Similarity
messages: Belongs to the UPF0179 family.

61858:DV706 RS12520
gene id: 61858:DV706_RS12520
uniprot id: A0A4D6HRF4
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

61858:DV706 RS01770
gene id: 61858:DV706_RS01770
uniprot id: A0A4D6HJ68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

61858:DV706 RS01725
gene id: 61858:DV706_RS01725
uniprot id: A0A4D6HHT8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS17270
gene id: 61858:DV706_RS17270
uniprot id: A0A4D6HT04
names: Similarity
messages: Belongs to the phosphoglycerate kinase family.

61858:DV706 RS10040
gene id: 61858:DV706_RS10040
uniprot id: A0A4D6HLG8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

61858:DV706 RS00870
gene id: 61858:DV706_RS00870
uniprot id: A0A4D6HK73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

61858:DV706 RS16020
gene id: 61858:DV706_RS16020
uniprot id: A0A4D6HPP4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

61858:DV706 RS09005
gene id: 61858:DV706_RS09005
uniprot id: A0A4D6HNG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS00290
gene id: 61858:DV706_RS00290
uniprot id: A0A4D6HQU8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS09210
gene id: 61858:DV706_RS09210
uniprot id: A0A4D6HNK0
names: Subcellular Location Annotation
messages: Nucleus

61858:DV706 RS05200
gene id: 61858:DV706_RS05200
uniprot id: A0A4D6HJB1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

61858:DV706 RS02495
gene id: 61858:DV706_RS02495
uniprot id: A0A4D6HQM2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS04460
gene id: 61858:DV706_RS04460
uniprot id: A0A4D6HKQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

61858:DV706 RS04625
gene id: 61858:DV706_RS04625
uniprot id: A0A4D6HJW7
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

61858:DV706 RS14515
gene id: 61858:DV706_RS14515
uniprot id: A0A4D6HQS7
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

61858:DV706 RS03170
gene id: 61858:DV706_RS03170
uniprot id: A0A4D6HIX8
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

61858:DV706 RS06120
gene id: 61858:DV706_RS06120
uniprot id: A0A4D6HLM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

61858:DV706 RS11930
gene id: 61858:DV706_RS11930
uniprot id: A0A4D6HNI5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS21030
gene id: 61858:DV706_RS21030
uniprot id: A0A4D6HU50
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

61858:DV706 RS12925
gene id: 61858:DV706_RS12925
uniprot id: A0A4D6HPX6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61858:DV706 RS11475
gene id: 61858:DV706_RS11475
uniprot id: A0A4D6HRD1
names: Similarity
messages: Belongs to the acylphosphatase family.

61858:DV706 RS05865
gene id: 61858:DV706_RS05865
uniprot id: A0A4D6HJN9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

61858:DV706 RS08785
gene id: 61858:DV706_RS08785
uniprot id: A0A4D6HL21
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

61858:DV706 RS14350
gene id: 61858:DV706_RS14350
uniprot id: A0A4D6HNY2
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

61858:DV706 RS03575
gene id: 61858:DV706_RS03575
uniprot id: A0A4D6HLP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

61858:DV706 RS07430
gene id: 61858:DV706_RS07430
uniprot id: A0A4D6HKG2
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS09625
gene id: 61858:DV706_RS09625
uniprot id: A0A4D6HPY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

61858:DV706 RS12420
gene id: 61858:DV706_RS12420
uniprot id: A0A4D6HMR6
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03665
gene id: 61858:DV706_RS03665
uniprot id: A0A4D6HIF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

61858:DV706 RS08525
gene id: 61858:DV706_RS08525
uniprot id: A0A4D6HN99
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

61858:DV706 RS20565
gene id: 61858:DV706_RS20565
uniprot id: A0A4D6HSK4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS10235
gene id: 61858:DV706_RS10235
uniprot id: A0A4D6HP33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

61858:DV706 RS02755
gene id: 61858:DV706_RS02755
uniprot id: A0A4D6HIA2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

61858:DV706 RS14380
gene id: 61858:DV706_RS14380
uniprot id: A0A4D6HQR3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS10280
gene id: 61858:DV706_RS10280
uniprot id: A0A4D6HML4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

61858:DV706 RS05475
gene id: 61858:DV706_RS05475
uniprot id: A0A4D6HQR1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

61858:DV706 RS10775
gene id: 61858:DV706_RS10775
uniprot id: A0A4D6HLU4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS05730
gene id: 61858:DV706_RS05730
uniprot id: A0A4D6HP63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

61858:DV706 RS21075
gene id: 61858:DV706_RS21075
uniprot id: A0A4D6HTG5
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS19515
gene id: 61858:DV706_RS19515
uniprot id: A0A4D6HRY7
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

61858:DV706 RS18840
gene id: 61858:DV706_RS18840
uniprot id: A0A4D6HTP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

61858:DV706 RS03970
gene id: 61858:DV706_RS03970
uniprot id: A0A4D6HJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

61858:DV706 RS09510
gene id: 61858:DV706_RS09510
uniprot id: A0A4D6HME7
names: Similarity
messages: Belongs to the HypE family.

61858:DV706 RS00735
gene id: 61858:DV706_RS00735
uniprot id: A0A4D6HH16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Belongs to the inositol monophosphatase superfamily.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS17040
gene id: 61858:DV706_RS17040
uniprot id: A0A4D6HJ13
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10620
gene id: 61858:DV706_RS10620
uniprot id: A0A4D6HNU9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS12210
gene id: 61858:DV706_RS12210
uniprot id: A0A4D6HNP6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

61858:DV706 RS00485
gene id: 61858:DV706_RS00485
uniprot id: A0A4D6HGE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS07915
gene id: 61858:DV706_RS07915
uniprot id: A0A4D6HMM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS03165
gene id: 61858:DV706_RS03165
uniprot id: A0A4D6HIH2
names: Similarity
messages: Belongs to the eIF-2-alpha family.

61858:DV706 RS07900
gene id: 61858:DV706_RS07900
uniprot id: A0A4D6HLN5
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

61858:DV706 RS10445
gene id: 61858:DV706_RS10445
uniprot id: A0A4D6HP06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

61858:DV706 RS09855
gene id: 61858:DV706_RS09855
uniprot id: A0A4D6HLM3
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS02380
gene id: 61858:DV706_RS02380
uniprot id: A0A4D6HGX1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS14765
gene id: 61858:DV706_RS14765
uniprot id: A0A4D6HP35
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

61858:DV706 RS12660
gene id: 61858:DV706_RS12660
uniprot id: A0A4D6HN77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

61858:DV706 RS19345
gene id: 61858:DV706_RS19345
uniprot id: A0A4D6HUF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

61858:DV706 RS03875
gene id: 61858:DV706_RS03875
uniprot id: A0A4D6HKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

61858:DV706 RS12620
gene id: 61858:DV706_RS12620
uniprot id: A0A4D6HM68
names: Similarity
messages: Belongs to the DtxR/MntR family.

61858:DV706 RS04250
gene id: 61858:DV706_RS04250
uniprot id: A0A4D6HIZ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

61858:DV706 RS21165
gene id: 61858:DV706_RS21165
uniprot id: A0A4D6HSX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS01125
gene id: 61858:DV706_RS01125
uniprot id: A0A4D6HQ92
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

61858:DV706 RS11810
gene id: 61858:DV706_RS11810
uniprot id: A0A4D6HMF4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS16285
gene id: 61858:DV706_RS16285
uniprot id: A0A4D6HGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

61858:DV706 RS00370
gene id: 61858:DV706_RS00370
uniprot id: A0A4D6HQB0
names: Similarity
messages: Belongs to the UPF0045 family.

61858:DV706 RS04165
gene id: 61858:DV706_RS04165
uniprot id: A0A4D6HIQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

61858:DV706 RS04665
gene id: 61858:DV706_RS04665
uniprot id: A0A4D6HIZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

61858:DV706 RS02580
gene id: 61858:DV706_RS02580
uniprot id: A0A4D6HR75
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

61858:DV706 RS20945
gene id: 61858:DV706_RS20945
uniprot id: A0A4D6HVD4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS16690
gene id: 61858:DV706_RS16690
uniprot id: A0A4D6HS16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS01865
gene id: 61858:DV706_RS01865
uniprot id: A0A4D6HJE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

61858:DV706 RS01250
gene id: 61858:DV706_RS01250
uniprot id: A0A4D6HGZ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

61858:DV706 RS14915
gene id: 61858:DV706_RS14915
uniprot id: A0A4D6HQR0
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

61858:DV706 RS16850
gene id: 61858:DV706_RS16850
uniprot id: A0A4D6HQU8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS03130
gene id: 61858:DV706_RS03130
uniprot id: A0A4D6HJ59
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS07650
gene id: 61858:DV706_RS07650
uniprot id: A0A4D6HKT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS13365
gene id: 61858:DV706_RS13365
uniprot id: A0A4D6HN52
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

61858:DV706 RS03120
gene id: 61858:DV706_RS03120
uniprot id: A0A4D6HI60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS02485
gene id: 61858:DV706_RS02485
uniprot id: A0A4D6HIK0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

61858:DV706 RS15715
gene id: 61858:DV706_RS15715
uniprot id: A0A4D6HJN3
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

61858:DV706 RS18925
gene id: 61858:DV706_RS18925
uniprot id: A0A4D6HU13
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS19070
gene id: 61858:DV706_RS19070
uniprot id: A0A4D6HTM4
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

61858:DV706 RS19870
gene id: 61858:DV706_RS19870
uniprot id: A0A4D6HSW3
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

61858:DV706 RS00795
gene id: 61858:DV706_RS00795
uniprot id: A0A4D6HH30
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS10840
gene id: 61858:DV706_RS10840
uniprot id: A0A4D6HPF3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

61858:DV706 RS11735
gene id: 61858:DV706_RS11735
uniprot id: A0A4D6HNN8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03595
gene id: 61858:DV706_RS03595
uniprot id: A0A4D6HJ64
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

61858:DV706 RS14790
gene id: 61858:DV706_RS14790
uniprot id: A0A4D6HQA4
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS16265
gene id: 61858:DV706_RS16265
uniprot id: A0A4D6HIN6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS11495
gene id: 61858:DV706_RS11495
uniprot id: A0A4D6HPR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS15425
gene id: 61858:DV706_RS15425
uniprot id: A0A4D6HJ57
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS12830
gene id: 61858:DV706_RS12830
uniprot id: A0A4D6HN97
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

61858:DV706 RS01475
gene id: 61858:DV706_RS01475
uniprot id: A0A4D6HSY2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS15665
gene id: 61858:DV706_RS15665
uniprot id: A0A4D6HSY2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS15705
gene id: 61858:DV706_RS15705
uniprot id: A0A4D6HQY6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS21100
gene id: 61858:DV706_RS21100
uniprot id: A0A4D6HV47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS03410
gene id: 61858:DV706_RS03410
uniprot id: A0A4D6HJB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

61858:DV706 RS02375
gene id: 61858:DV706_RS02375
uniprot id: A0A4D6HHT2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

61858:DV706 RS13645
gene id: 61858:DV706_RS13645
uniprot id: A0A4D6HPS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

61858:DV706 RS00980
gene id: 61858:DV706_RS00980
uniprot id: A0A4D6HK94
names: Similarity
messages: Belongs to the FabD family.

61858:DV706 RS11780
gene id: 61858:DV706_RS11780
uniprot id: A0A4D6HMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

61858:DV706 RS19405
gene id: 61858:DV706_RS19405
uniprot id: A0A4D6HSM1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

61858:DV706 RS10315
gene id: 61858:DV706_RS10315
uniprot id: A0A4D6HNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

61858:DV706 RS17505
gene id: 61858:DV706_RS17505
uniprot id: A0A4D6HQQ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS04765
gene id: 61858:DV706_RS04765
uniprot id: A0A4D6HL81
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

61858:DV706 RS02270
gene id: 61858:DV706_RS02270
uniprot id: A0A4D6HHR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

61858:DV706 RS06695
gene id: 61858:DV706_RS06695
uniprot id: A0A4D6HQT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS04020
gene id: 61858:DV706_RS04020
uniprot id: A0A4D6HHQ0
names: Similarity
messages: Belongs to the peptidase C59 family.

61858:DV706 RS04490
gene id: 61858:DV706_RS04490
uniprot id: A0A4D6HIX0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS13625
gene id: 61858:DV706_RS13625
uniprot id: A0A4D6HPD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61858:DV706 RS05480
gene id: 61858:DV706_RS05480
uniprot id: A0A4D6HJG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS10180
gene id: 61858:DV706_RS10180
uniprot id: A0A4D6HRB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61858:DV706 RS19900
gene id: 61858:DV706_RS19900
uniprot id: A0A4D6HTM8
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS14720
gene id: 61858:DV706_RS14720
uniprot id: A0A4D6HR84
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

61858:DV706 RS17680
gene id: 61858:DV706_RS17680
uniprot id: A0A4D6HTF1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

61858:DV706 RS09725
gene id: 61858:DV706_RS09725
uniprot id: A0A4D6HLK3
names: Similarity
messages: Belongs to the RutC family.

61858:DV706 RS10595
gene id: 61858:DV706_RS10595
uniprot id: A0A4D6HKX7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS18810
gene id: 61858:DV706_RS18810
uniprot id: A0A4D6HUL3
names: Similarity
messages: Belongs to the SUI1 family.

61858:DV706 RS00255
gene id: 61858:DV706_RS00255
uniprot id: A0A4D6HJW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS04660
gene id: 61858:DV706_RS04660
uniprot id: A0A4D6HL66
names: Similarity
messages: Belongs to the PdaD family.

61858:DV706 RS07315
gene id: 61858:DV706_RS07315
uniprot id: A0A4D6HMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS16725
gene id: 61858:DV706_RS16725
uniprot id: A0A4D6HHP7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

61858:DV706 RS11875
gene id: 61858:DV706_RS11875
uniprot id: A0A4D6HPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

61858:DV706 RS14860
gene id: 61858:DV706_RS14860
uniprot id: A0A4D6HQQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS12810
gene id: 61858:DV706_RS12810
uniprot id: A0A4D6HQ35
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

61858:DV706 RS08035
gene id: 61858:DV706_RS08035
uniprot id: A0A4D6HPA4
names: Similarity
messages: Belongs to the AOR/FOR family.

61858:DV706 RS00845
gene id: 61858:DV706_RS00845
uniprot id: A0A4D6HH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

61858:DV706 RS15920
gene id: 61858:DV706_RS15920
uniprot id: A0A4D6HPM2
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS11380
gene id: 61858:DV706_RS11380
uniprot id: A0A4D6HPP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

61858:DV706 RS00475
gene id: 61858:DV706_RS00475
uniprot id: A0A4D6HJZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

61858:DV706 RS04910
gene id: 61858:DV706_RS04910
uniprot id: A0A4D6HJB4
names: Similarity
messages: Belongs to the UPF0146 family.

61858:DV706 RS06845
gene id: 61858:DV706_RS06845
uniprot id: A0A4D6HLX9
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS11205
gene id: 61858:DV706_RS11205
uniprot id: A0A4D6HN23
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

61858:DV706 RS15135
gene id: 61858:DV706_RS15135
uniprot id: A0A4D6HNY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

61858:DV706 RS07320
gene id: 61858:DV706_RS07320
uniprot id: A0A4D6HKE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS05235
gene id: 61858:DV706_RS05235
uniprot id: A0A4D6HMJ9
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

61858:DV706 RS21070
gene id: 61858:DV706_RS21070
uniprot id: A0A4D6HSV4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

61858:DV706 RS14800
gene id: 61858:DV706_RS14800
uniprot id: A0A4D6HRP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS12705
gene id: 61858:DV706_RS12705
uniprot id: A0A4D6HRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane

61858:DV706 RS06445
gene id: 61858:DV706_RS06445
uniprot id: A0A4D6HIZ5
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06340
gene id: 61858:DV706_RS06340
uniprot id: A0A4D6HIX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

61858:DV706 RS04480
gene id: 61858:DV706_RS04480
uniprot id: A0A4D6HJP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

61858:DV706 RS03325
gene id: 61858:DV706_RS03325
uniprot id: A0A4D6HHZ3
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

61858:DV706 RS13700
gene id: 61858:DV706_RS13700
uniprot id: A0A4D6HPT2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS14265
gene id: 61858:DV706_RS14265
uniprot id: A0A4D6HQ28
names: Similarity
messages: Belongs to the UPF0145 family.

61858:DV706 RS17100
gene id: 61858:DV706_RS17100
uniprot id: A0A4D6HHD1
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS09165
gene id: 61858:DV706_RS09165
uniprot id: A0A4D6HK96
names: Similarity
messages: Belongs to the AOR/FOR family.

61858:DV706 RS05780
gene id: 61858:DV706_RS05780
uniprot id: A0A4D6HLF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

61858:DV706 RS17060
gene id: 61858:DV706_RS17060
uniprot id: A0A4D6HQH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS19085
gene id: 61858:DV706_RS19085
uniprot id: A0A4D6HRL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

61858:DV706 RS20000
gene id: 61858:DV706_RS20000
uniprot id: A0A4D6HUE1
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS12845
gene id: 61858:DV706_RS12845
uniprot id: A0A4D6HMX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

61858:DV706 RS03095
gene id: 61858:DV706_RS03095
uniprot id: A0A4D6HJY2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS03115
gene id: 61858:DV706_RS03115
uniprot id: A0A4D6HKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS12680
gene id: 61858:DV706_RS12680
uniprot id: A0A4D6HM75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

61858:DV706 RS11135
gene id: 61858:DV706_RS11135
uniprot id: A0A4D6HQP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS01925
gene id: 61858:DV706_RS01925
uniprot id: A0A4D6HJA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS05485
gene id: 61858:DV706_RS05485
uniprot id: A0A4D6HIJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS13370
gene id: 61858:DV706_RS13370
uniprot id: A0A4D6HMJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS05295
gene id: 61858:DV706_RS05295
uniprot id: A0A4D6HL57
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS10615
gene id: 61858:DV706_RS10615
uniprot id: A0A4D6HR06
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS11195
gene id: 61858:DV706_RS11195
uniprot id: A0A4D6HM33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

61858:DV706 RS15600
gene id: 61858:DV706_RS15600
uniprot id: A0A4D6HH42
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS15270
gene id: 61858:DV706_RS15270
uniprot id: A0A4D6HS14
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

61858:DV706 RS18740
gene id: 61858:DV706_RS18740
uniprot id: A0A4D6HT00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS03990
gene id: 61858:DV706_RS03990
uniprot id: A0A4D6HKF1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

61858:DV706 RS11260
gene id: 61858:DV706_RS11260
uniprot id: A0A4D6HPM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS07680
gene id: 61858:DV706_RS07680
uniprot id: A0A4D6HM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

61858:DV706 RS03010
gene id: 61858:DV706_RS03010
uniprot id: A0A4D6HI41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

61858:DV706 RS16740
gene id: 61858:DV706_RS16740
uniprot id: A0A4D6HJ63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS02725
gene id: 61858:DV706_RS02725
uniprot id: A0A4D6HH25
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

61858:DV706 RS11770
gene id: 61858:DV706_RS11770
uniprot id: A0A4D6HNE9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

61858:DV706 RS02355
gene id: 61858:DV706_RS02355
uniprot id: A0A4D6HI35
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

61858:DV706 RS16835
gene id: 61858:DV706_RS16835
uniprot id: A0A4D6HJX8
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

61858:DV706 RS09065
gene id: 61858:DV706_RS09065
uniprot id: A0A4D6HK75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

61858:DV706 RS07635
gene id: 61858:DV706_RS07635
uniprot id: A0A4D6HMI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

61858:DV706 RS10245
gene id: 61858:DV706_RS10245
uniprot id: A0A4D6HKS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS15290
gene id: 61858:DV706_RS15290
uniprot id: A0A4D6HR44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS00815
gene id: 61858:DV706_RS00815
uniprot id: A0A4D6HK62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

61858:DV706 RS00060
gene id: 61858:DV706_RS00060
uniprot id: A0A4D6HHI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

61858:DV706 RS06965
gene id: 61858:DV706_RS06965
uniprot id: A0A4D6HM67
names: Similarity
messages: Belongs to the peptidase M20A family.

61858:DV706 RS11500
gene id: 61858:DV706_RS11500
uniprot id: A0A4D6HM93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

61858:DV706 RS19590
gene id: 61858:DV706_RS19590
uniprot id: A0A4D6HS37
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

61858:DV706 RS16655
gene id: 61858:DV706_RS16655
uniprot id: A0A4D6HGE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS12915
gene id: 61858:DV706_RS12915
uniprot id: A0A4D6HQ54
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

61858:DV706 RS06280
gene id: 61858:DV706_RS06280
uniprot id: A0A4D6HJW6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS16160
gene id: 61858:DV706_RS16160
uniprot id: A0A4D6HK94
names: Similarity
messages: Belongs to the FabD family.

61858:DV706 RS03330
gene id: 61858:DV706_RS03330
uniprot id: A0A4D6HIJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS16875
gene id: 61858:DV706_RS16875
uniprot id: A0A4D6HGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS07180
gene id: 61858:DV706_RS07180
uniprot id: A0A4D6HQU4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

61858:DV706 RS00850
gene id: 61858:DV706_RS00850
uniprot id: A0A4D6HRH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

61858:DV706 RS03055
gene id: 61858:DV706_RS03055
uniprot id: A0A4D6HIV7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

61858:DV706 RS10075
gene id: 61858:DV706_RS10075
uniprot id: A0A4D6HNE2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS03615
gene id: 61858:DV706_RS03615
uniprot id: A0A4D6HJF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

61858:DV706 RS12430
gene id: 61858:DV706_RS12430
uniprot id: A0A4D6HNU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS15970
gene id: 61858:DV706_RS15970
uniprot id: A0A4D6HPN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

61858:DV706 RS15175
gene id: 61858:DV706_RS15175
uniprot id: A0A4D6HR26
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10110
gene id: 61858:DV706_RS10110
uniprot id: A0A4D6HLS1
names: Subcellular Location Annotation
messages: Cell membrane

61858:DV706 RS00855
gene id: 61858:DV706_RS00855
uniprot id: A0A4D6HGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

61858:DV706 RS04825
gene id: 61858:DV706_RS04825
uniprot id: A0A4D6HI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

61858:DV706 RS11965
gene id: 61858:DV706_RS11965
uniprot id: A0A4D6HR50
names: Similarity
messages: Belongs to the archease family.

61858:DV706 RS09535
gene id: 61858:DV706_RS09535
uniprot id: A0A4D6HLK0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10920
gene id: 61858:DV706_RS10920
uniprot id: A0A4D6HRC1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

61858:DV706 RS09425
gene id: 61858:DV706_RS09425
uniprot id: A0A4D6HM63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS02325
gene id: 61858:DV706_RS02325
uniprot id: A0A4D6HGW1
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05110
gene id: 61858:DV706_RS05110
uniprot id: A0A4D6HK48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

61858:DV706 RS07920
gene id: 61858:DV706_RS07920
uniprot id: A0A4D6HKF5
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05900
gene id: 61858:DV706_RS05900
uniprot id: A0A4D6HJW3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

61858:DV706 RS15140
gene id: 61858:DV706_RS15140
uniprot id: A0A4D6HP93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

61858:DV706 RS04195
gene id: 61858:DV706_RS04195
uniprot id: A0A4D6HIF3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

61858:DV706 RS12770
gene id: 61858:DV706_RS12770
uniprot id: A0A4D6HMW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

61858:DV706 RS20460
gene id: 61858:DV706_RS20460
uniprot id: A0A4D6HUR1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

61858:DV706 RS00970
gene id: 61858:DV706_RS00970
uniprot id: A0A4D6HI13
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

61858:DV706 RS20125
gene id: 61858:DV706_RS20125
uniprot id: A0A4D6HVI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS03105
gene id: 61858:DV706_RS03105
uniprot id: A0A4D6HIG5
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

61858:DV706 RS11565
gene id: 61858:DV706_RS11565
uniprot id: A0A4D6HPD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

61858:DV706 RS19195
gene id: 61858:DV706_RS19195
uniprot id: A0A4D6HRP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS03870
gene id: 61858:DV706_RS03870
uniprot id: A0A4D6HLT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS00875
gene id: 61858:DV706_RS00875
uniprot id: A0A4D6HIN6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS00570
gene id: 61858:DV706_RS00570
uniprot id: A0A4D6HHT6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

61858:DV706 RS00445
gene id: 61858:DV706_RS00445
uniprot id: A0A4D6HSJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

61858:DV706 RS03235
gene id: 61858:DV706_RS03235
uniprot id: A0A4D6HKI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

61858:DV706 RS10225
gene id: 61858:DV706_RS10225
uniprot id: A0A4D6HLU3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS13055
gene id: 61858:DV706_RS13055
uniprot id: A0A4D6HN13
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61858:DV706 RS03180
gene id: 61858:DV706_RS03180
uniprot id: A0A4D6HSG6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

61858:DV706 RS02190
gene id: 61858:DV706_RS02190
uniprot id: A0A4D6HJH1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

61858:DV706 RS08745
gene id: 61858:DV706_RS08745
uniprot id: A0A4D6HMY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

61858:DV706 RS03255
gene id: 61858:DV706_RS03255
uniprot id: A0A4D6HJ81
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS05935
gene id: 61858:DV706_RS05935
uniprot id: A0A4D6HN20
names: Subcellular Location Annotation
messages: Cytoplasm

61858:DV706 RS05665
gene id: 61858:DV706_RS05665
uniprot id: A0A4D6HLC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

61858:DV706 RS02830
gene id: 61858:DV706_RS02830
uniprot id: A0A4D6HI15
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06850
gene id: 61858:DV706_RS06850
uniprot id: A0A4D6HNL8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS19890
gene id: 61858:DV706_RS19890
uniprot id: A0A4D6HSH6
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

61858:DV706 RS19385
gene id: 61858:DV706_RS19385
uniprot id: A0A4D6HU00
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07770
gene id: 61858:DV706_RS07770
uniprot id: A0A4D6HKL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

61858:DV706 RS06090
gene id: 61858:DV706_RS06090
uniprot id: A0A4D6HJT6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

61858:DV706 RS05805
gene id: 61858:DV706_RS05805
uniprot id: A0A4D6HLW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

61858:DV706 RS04150
gene id: 61858:DV706_RS04150
uniprot id: A0A4D6HJI0
names: Similarity
messages: Belongs to the thymidylate kinase family.

61858:DV706 RS10735
gene id: 61858:DV706_RS10735
uniprot id: A0A4D6HMT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

61858:DV706 RS08175
gene id: 61858:DV706_RS08175
uniprot id: A0A4D6HKT2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

61858:DV706 RS16420
gene id: 61858:DV706_RS16420
uniprot id: A0A4D6HH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61858:DV706 RS14465
gene id: 61858:DV706_RS14465
uniprot id: A0A4D6HS39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

61858:DV706 RS02285
gene id: 61858:DV706_RS02285
uniprot id: A0A4D6HJL7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

61858:DV706 RS00535
gene id: 61858:DV706_RS00535
uniprot id: A0A4D6HGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

61858:DV706 RS19930
gene id: 61858:DV706_RS19930
uniprot id: A0A4D6HUI0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

61858:DV706 RS11445
gene id: 61858:DV706_RS11445
uniprot id: A0A4D6HLF5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

61858:DV706 RS07500
gene id: 61858:DV706_RS07500
uniprot id: A0A4D6HLH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS13275
gene id: 61858:DV706_RS13275
uniprot id: A0A4D6HSS0
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

61858:DV706 RS11185
gene id: 61858:DV706_RS11185
uniprot id: A0A4D6HQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

61858:DV706 RS01795
gene id: 61858:DV706_RS01795
uniprot id: A0A4D6HUV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS14365
gene id: 61858:DV706_RS14365
uniprot id: A0A4D6HNM1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

61858:DV706 RS10630
gene id: 61858:DV706_RS10630
uniprot id: A0A4D6HM26
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

61858:DV706 RS00440
gene id: 61858:DV706_RS00440
uniprot id: A0A4D6HTM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS06620
gene id: 61858:DV706_RS06620
uniprot id: A0A4D6HNG9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

61858:DV706 RS16890
gene id: 61858:DV706_RS16890
uniprot id: A0A4D6HRT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS12635
gene id: 61858:DV706_RS12635
uniprot id: A0A4D6HQ11
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

61858:DV706 RS12195
gene id: 61858:DV706_RS12195
uniprot id: A0A4D6HPL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

61858:DV706 RS04935
gene id: 61858:DV706_RS04935
uniprot id: A0A4D6HNQ7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS10800
gene id: 61858:DV706_RS10800
uniprot id: A0A4D6HL15
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06030
gene id: 61858:DV706_RS06030
uniprot id: A0A4D6HM09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

61858:DV706 RS07875
gene id: 61858:DV706_RS07875
uniprot id: A0A4D6HKX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

61858:DV706 RS11640
gene id: 61858:DV706_RS11640
uniprot id: A0A4D6HMN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61858:DV706 RS17380
gene id: 61858:DV706_RS17380
uniprot id: A0A4D6HQM8
names: Similarity
messages: Belongs to the peptidase S8 family.

61858:DV706 RS06660
gene id: 61858:DV706_RS06660
uniprot id: A0A4D6HK38
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

61858:DV706 RS07910
gene id: 61858:DV706_RS07910
uniprot id: A0A4D6HP83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

61858:DV706 RS06420
gene id: 61858:DV706_RS06420
uniprot id: A0A4D6HJP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

61858:DV706 RS05195
gene id: 61858:DV706_RS05195
uniprot id: A0A4D6HLI2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS11250
gene id: 61858:DV706_RS11250
uniprot id: A0A4D6HMG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS10220
gene id: 61858:DV706_RS10220
uniprot id: A0A4D6HLJ8
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

61858:DV706 RS03345
gene id: 61858:DV706_RS03345
uniprot id: A0A4D6HI96
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

61858:DV706 RS21040
gene id: 61858:DV706_RS21040
uniprot id: A0A4D6HT02
names: Subcellular Location Annotation
messages: Cytoplasm

61858:DV706 RS16805
gene id: 61858:DV706_RS16805
uniprot id: A0A4D6HJ51
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

61858:DV706 RS03395
gene id: 61858:DV706_RS03395
uniprot id: A0A4D6HKK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

61858:DV706 RS08545
gene id: 61858:DV706_RS08545
uniprot id: A0A4D6HMK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS05125
gene id: 61858:DV706_RS05125
uniprot id: A0A4D6HL24
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

61858:DV706 RS07165
gene id: 61858:DV706_RS07165
uniprot id: A0A4D6HMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

61858:DV706 RS03085
gene id: 61858:DV706_RS03085
uniprot id: A0A4D6HK05
names: Subcellular Location Annotation
messages: Cytoplasm

61858:DV706 RS03515
gene id: 61858:DV706_RS03515
uniprot id: A0A4D6HJD5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS17875
gene id: 61858:DV706_RS17875
uniprot id: A0A4D6HQX1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS03050
gene id: 61858:DV706_RS03050
uniprot id: A0A4D6HIF8
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

61858:DV706 RS13760
gene id: 61858:DV706_RS13760
uniprot id: A0A4D6HQG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

61858:DV706 RS13545
gene id: 61858:DV706_RS13545
uniprot id: A0A4D6HQD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

61858:DV706 RS13295
gene id: 61858:DV706_RS13295
uniprot id: A0A4D6HN51
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

61858:DV706 RS12080
gene id: 61858:DV706_RS12080
uniprot id: A0A4D6HR71
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07515
gene id: 61858:DV706_RS07515
uniprot id: A0A4D6HMF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

61858:DV706 RS07605
gene id: 61858:DV706_RS07605
uniprot id: A0A4D6HKI5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

61858:DV706 RS20920
gene id: 61858:DV706_RS20920
uniprot id: A0A4D6HSR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61858:DV706 RS10650
gene id: 61858:DV706_RS10650
uniprot id: A0A4D6HKY8
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

61858:DV706 RS07600
gene id: 61858:DV706_RS07600
uniprot id: A0A4D6HMW5
names: Similarity
messages: Belongs to the threonine aldolase family.

61858:DV706 RS10410
gene id: 61858:DV706_RS10410
uniprot id: A0A4D6HPN1
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

61858:DV706 RS12670
gene id: 61858:DV706_RS12670
uniprot id: A0A4D6HQF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

61858:DV706 RS10485
gene id: 61858:DV706_RS10485
uniprot id: A0A4D6HLW9
names: Similarity
messages: Belongs to the HypE family.

61858:DV706 RS19090
gene id: 61858:DV706_RS19090
uniprot id: A0A4D6HSA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS16330
gene id: 61858:DV706_RS16330
uniprot id: A0A4D6HIY4
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

61858:DV706 RS09550
gene id: 61858:DV706_RS09550
uniprot id: A0A4D6HRH6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

61858:DV706 RS11255
gene id: 61858:DV706_RS11255
uniprot id: A0A4D6HN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS02570
gene id: 61858:DV706_RS02570
uniprot id: A0A4D6HL69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS13455
gene id: 61858:DV706_RS13455
uniprot id: A0A4D6HNK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

61858:DV706 RS10600
gene id: 61858:DV706_RS10600
uniprot id: A0A4D6HMZ4
names: Similarity
messages: Belongs to the RutC family.

61858:DV706 RS11635
gene id: 61858:DV706_RS11635
uniprot id: A0A4D6HMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

61858:DV706 RS19400
gene id: 61858:DV706_RS19400
uniprot id: A0A4D6HRZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS07270
gene id: 61858:DV706_RS07270
uniprot id: A0A4D6HKD8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

61858:DV706 RS03900
gene id: 61858:DV706_RS03900
uniprot id: A0A4D6HKU6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

61858:DV706 RS02985
gene id: 61858:DV706_RS02985
uniprot id: A0A4D6HJW1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS17790
gene id: 61858:DV706_RS17790
uniprot id: A0A4D6HSZ9
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS15285
gene id: 61858:DV706_RS15285
uniprot id: A0A4D6HPU6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

61858:DV706 RS04895
gene id: 61858:DV706_RS04895
uniprot id: A0A4D6HMD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS09080
gene id: 61858:DV706_RS09080
uniprot id: A0A4D6HPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

61858:DV706 RS09460
gene id: 61858:DV706_RS09460
uniprot id: A0A4D6HMD4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

61858:DV706 RS00720
gene id: 61858:DV706_RS00720
uniprot id: A0A4D6HH91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61858:DV706 RS07995
gene id: 61858:DV706_RS07995
uniprot id: A0A4D6HKY6
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07345
gene id: 61858:DV706_RS07345
uniprot id: A0A4D6HMC9
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

61858:DV706 RS08180
gene id: 61858:DV706_RS08180
uniprot id: A0A4D6HJT8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

61858:DV706 RS19275
gene id: 61858:DV706_RS19275
uniprot id: A0A4D6HJ79
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

61858:DV706 RS06570
gene id: 61858:DV706_RS06570
uniprot id: A0A4D6HNF8
names: Similarity
messages: Belongs to the cytochrome P450 family.

61858:DV706 RS13695
gene id: 61858:DV706_RS13695
uniprot id: A0A4D6HMQ4
names: Similarity
messages: Belongs to the AOR/FOR family.

61858:DV706 RS10300
gene id: 61858:DV706_RS10300
uniprot id: A0A4D6HMT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS20105
gene id: 61858:DV706_RS20105
uniprot id: A0A4D6HSL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS00415
gene id: 61858:DV706_RS00415
uniprot id: A0A4D6HHP7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

61858:DV706 RS03275
gene id: 61858:DV706_RS03275
uniprot id: A0A4D6HHY4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS14510
gene id: 61858:DV706_RS14510
uniprot id: A0A4D6HQ60
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

61858:DV706 RS02060
gene id: 61858:DV706_RS02060
uniprot id: A0A4D6HJZ3
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS02940
gene id: 61858:DV706_RS02940
uniprot id: A0A4D6HNN3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS14905
gene id: 61858:DV706_RS14905
uniprot id: A0A4D6HQY5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

61858:DV706 RS09260
gene id: 61858:DV706_RS09260
uniprot id: A0A4D6HM34
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS02370
gene id: 61858:DV706_RS02370
uniprot id: A0A4D6HK50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS21095
gene id: 61858:DV706_RS21095
uniprot id: A0A4D6HUE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

61858:DV706 RS07455
gene id: 61858:DV706_RS07455
uniprot id: A0A4D6HM58
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

61858:DV706 RS12015
gene id: 61858:DV706_RS12015
uniprot id: A0A4D6HPM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

61858:DV706 RS05350
gene id: 61858:DV706_RS05350
uniprot id: A0A4D6HJK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

61858:DV706 RS05990
gene id: 61858:DV706_RS05990
uniprot id: A0A4D6HKM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

61858:DV706 RS11645
gene id: 61858:DV706_RS11645
uniprot id: A0A4D6HNC0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS15445
gene id: 61858:DV706_RS15445
uniprot id: A0A4D6HGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

61858:DV706 RS11035
gene id: 61858:DV706_RS11035
uniprot id: A0A4D6HP36
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS04995
gene id: 61858:DV706_RS04995
uniprot id: A0A4D6HL04
names: Similarity
messages: Belongs to the PDCD5 family.

61858:DV706 RS16220
gene id: 61858:DV706_RS16220
uniprot id: A0A4D6HSI8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

61858:DV706 RS05650
gene id: 61858:DV706_RS05650
uniprot id: A0A4D6HKG3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61858:DV706 RS05545
gene id: 61858:DV706_RS05545
uniprot id: A0A4D6HKD9
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

61858:DV706 RS13500
gene id: 61858:DV706_RS13500
uniprot id: A0A4D6HPI7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS11540
gene id: 61858:DV706_RS11540
uniprot id: A0A4D6HN96
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

61858:DV706 RS04035
gene id: 61858:DV706_RS04035
uniprot id: A0A4D6HKG6
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

61858:DV706 RS08535
gene id: 61858:DV706_RS08535
uniprot id: A0A4D6HJY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

61858:DV706 RS02930
gene id: 61858:DV706_RS02930
uniprot id: A0A4D6HJV4
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03290
gene id: 61858:DV706_RS03290
uniprot id: A0A4D6HKJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

61858:DV706 RS04905
gene id: 61858:DV706_RS04905
uniprot id: A0A4D6HIV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

61858:DV706 RS03580
gene id: 61858:DV706_RS03580
uniprot id: A0A4D6HK81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

61858:DV706 RS07095
gene id: 61858:DV706_RS07095
uniprot id: A0A4D6HPH6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS04840
gene id: 61858:DV706_RS04840
uniprot id: A0A4D6HKY0
names: Similarity
messages: Belongs to the NAD synthetase family.

61858:DV706 RS15325
gene id: 61858:DV706_RS15325
uniprot id: A0A4D6HP81
names: Similarity
messages: Belongs to the Nth/MutY family.

61858:DV706 RS15310
gene id: 61858:DV706_RS15310
uniprot id: A0A4D6HPC5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

61858:DV706 RS13550
gene id: 61858:DV706_RS13550
uniprot id: A0A4D6HRS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

61858:DV706 RS05985
gene id: 61858:DV706_RS05985
uniprot id: A0A4D6HIS5
names: Similarity
messages: Belongs to the UPF0201 family.

61858:DV706 RS08950
gene id: 61858:DV706_RS08950
uniprot id: A0A4D6HL51
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

61858:DV706 RS11830
gene id: 61858:DV706_RS11830
uniprot id: A0A4D6HME4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

61858:DV706 RS04160
gene id: 61858:DV706_RS04160
uniprot id: A0A4D6HKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

61858:DV706 RS16575
gene id: 61858:DV706_RS16575
uniprot id: A0A4D6HG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

61858:DV706 RS07580
gene id: 61858:DV706_RS07580
uniprot id: A0A4D6HK88
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS03300
gene id: 61858:DV706_RS03300
uniprot id: A0A4D6HHB6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS00505
gene id: 61858:DV706_RS00505
uniprot id: A0A4D6HGX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS21085
gene id: 61858:DV706_RS21085
uniprot id: A0A4D6HT10
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

61858:DV706 RS11125
gene id: 61858:DV706_RS11125
uniprot id: A0A4D6HNB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61858:DV706 RS06440
gene id: 61858:DV706_RS06440
uniprot id: A0A4D6HK00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

61858:DV706 RS15210
gene id: 61858:DV706_RS15210
uniprot id: A0A4D6HRF0
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

61858:DV706 RS04055
gene id: 61858:DV706_RS04055
uniprot id: A0A4D6HKX1
names: Similarity
messages: Belongs to the PspA/IM30 family.

61858:DV706 RS03360
gene id: 61858:DV706_RS03360
uniprot id: A0A4D6HK54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

61858:DV706 RS17425
gene id: 61858:DV706_RS17425
uniprot id: A0A4D6HSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

61858:DV706 RS12460
gene id: 61858:DV706_RS12460
uniprot id: A0A4D6HP39
names: Similarity
messages: Belongs to the glutaredoxin family.

61858:DV706 RS08730
gene id: 61858:DV706_RS08730
uniprot id: A0A4D6HM17
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

61858:DV706 RS04820
gene id: 61858:DV706_RS04820
uniprot id: A0A4D6HJ34
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS04610
gene id: 61858:DV706_RS04610
uniprot id: A0A4D6HL56
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07395
gene id: 61858:DV706_RS07395
uniprot id: A0A4D6HM51
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

61858:DV706 RS03910
gene id: 61858:DV706_RS03910
uniprot id: A0A4D6HHN0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

61858:DV706 RS16315
gene id: 61858:DV706_RS16315
uniprot id: A0A4D6HGP3
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

61858:DV706 RS17095
gene id: 61858:DV706_RS17095
uniprot id: A0A4D6HS82
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

61858:DV706 RS16320
gene id: 61858:DV706_RS16320
uniprot id: A0A4D6HQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

61858:DV706 RS19395
gene id: 61858:DV706_RS19395
uniprot id: A0A4D6HUG4
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

61858:DV706 RS00480
gene id: 61858:DV706_RS00480
uniprot id: A0A4D6HQ85
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

61858:DV706 RS05870
gene id: 61858:DV706_RS05870
uniprot id: A0A4D6HIR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

61858:DV706 RS14945
gene id: 61858:DV706_RS14945
uniprot id: A0A4D6HND8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

61858:DV706 RS07755
gene id: 61858:DV706_RS07755
uniprot id: A0A4D6HKV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

61858:DV706 RS14605
gene id: 61858:DV706_RS14605
uniprot id: A0A4D6HNR3
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS19185
gene id: 61858:DV706_RS19185
uniprot id: A0A4D6HU68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS05850
gene id: 61858:DV706_RS05850
uniprot id: A0A4D6HJV2
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS05285
gene id: 61858:DV706_RS05285
uniprot id: A0A4D6HL43
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS20950
gene id: 61858:DV706_RS20950
uniprot id: A0A4D6HST1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

61858:DV706 RS01170
gene id: 61858:DV706_RS01170
uniprot id: A0A4D6HPN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

61858:DV706 RS03155
gene id: 61858:DV706_RS03155
uniprot id: A0A4D6HK01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS13090
gene id: 61858:DV706_RS13090
uniprot id: A0A4D6HPF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS09755
gene id: 61858:DV706_RS09755
uniprot id: A0A4D6HQ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

61858:DV706 RS00635
gene id: 61858:DV706_RS00635
uniprot id: A0A4D6HIV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

61858:DV706 RS16625
gene id: 61858:DV706_RS16625
uniprot id: A0A4D6HHS4
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS12085
gene id: 61858:DV706_RS12085
uniprot id: A0A4D6HPJ6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

61858:DV706 RS06070
gene id: 61858:DV706_RS06070
uniprot id: A0A4D6HJH0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

61858:DV706 RS18835
gene id: 61858:DV706_RS18835
uniprot id: A0A4D6HSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

61858:DV706 RS03190
gene id: 61858:DV706_RS03190
uniprot id: A0A4D6HH97
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

61858:DV706 RS16130
gene id: 61858:DV706_RS16130
uniprot id: A0A4D6HRN9
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07390
gene id: 61858:DV706_RS07390
uniprot id: A0A4D6HSK8
names: Similarity
messages: Belongs to the HMBS family.

61858:DV706 RS16635
gene id: 61858:DV706_RS16635
uniprot id: A0A4D6HGX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS06350
gene id: 61858:DV706_RS06350
uniprot id: A0A4D6HLN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

61858:DV706 RS21195
gene id: 61858:DV706_RS21195
uniprot id: A0A4D6HT29
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

61858:DV706 RS11755
gene id: 61858:DV706_RS11755
uniprot id: A0A4D6HPF0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

61858:DV706 RS08805
gene id: 61858:DV706_RS08805
uniprot id: A0A4D6HPK8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

61858:DV706 RS11365
gene id: 61858:DV706_RS11365
uniprot id: A0A4D6HM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

61858:DV706 RS06590
gene id: 61858:DV706_RS06590
uniprot id: A0A4D6HKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

61858:DV706 RS00515
gene id: 61858:DV706_RS00515
uniprot id: A0A4D6HHS4
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS00040
gene id: 61858:DV706_RS00040
uniprot id: A0A4D6HHD1
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS17070
gene id: 61858:DV706_RS17070
uniprot id: A0A4D6HRA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS09250
gene id: 61858:DV706_RS09250
uniprot id: A0A4D6HL30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Membrane
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

61858:DV706 RS06385
gene id: 61858:DV706_RS06385
uniprot id: A0A4D6HM98
names: Similarity
messages: Belongs to the IMPACT family.

61858:DV706 RS05290
gene id: 61858:DV706_RS05290
uniprot id: A0A4D6HMK7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS16685
gene id: 61858:DV706_RS16685
uniprot id: A0A4D6HQ82
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

61858:DV706 RS15910
gene id: 61858:DV706_RS15910
uniprot id: A0A4D6HI82
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS14885
gene id: 61858:DV706_RS14885
uniprot id: A0A4D6HNX3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

61858:DV706 RS05960
gene id: 61858:DV706_RS05960
uniprot id: A0A4D6HLZ9
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS04400
gene id: 61858:DV706_RS04400
uniprot id: A0A4D6HM48
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS18205
gene id: 61858:DV706_RS18205
uniprot id: A0A4D6HTP4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

61858:DV706 RS01120
gene id: 61858:DV706_RS01120
uniprot id: A0A4D6HPP4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

61858:DV706 RS15415
gene id: 61858:DV706_RS15415
uniprot id: A0A4D6HHT8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS08985
gene id: 61858:DV706_RS08985
uniprot id: A0A4D6HN18
names: Similarity
messages: Belongs to the UPF0215 family.

61858:DV706 RS15370
gene id: 61858:DV706_RS15370
uniprot id: A0A4D6HJ68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

61858:DV706 RS03680
gene id: 61858:DV706_RS03680
uniprot id: A0A4D6HJG7
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03390
gene id: 61858:DV706_RS03390
uniprot id: A0A4D6HJ16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

61858:DV706 RS08840
gene id: 61858:DV706_RS08840
uniprot id: A0A4D6HM35
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

61858:DV706 RS00460
gene id: 61858:DV706_RS00460
uniprot id: A0A4D6HG68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

61858:DV706 RS10010
gene id: 61858:DV706_RS10010
uniprot id: A0A4D6HKN5
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS11980
gene id: 61858:DV706_RS11980
uniprot id: A0A4D6HMU1
names: Subcellular Location Annotation
messages: Nucleus

61858:DV706 RS10455
gene id: 61858:DV706_RS10455
uniprot id: A0A4D6HQB5
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS11040
gene id: 61858:DV706_RS11040
uniprot id: A0A4D6HLZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

61858:DV706 RS00425
gene id: 61858:DV706_RS00425
uniprot id: A0A4D6HR29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS06920
gene id: 61858:DV706_RS06920
uniprot id: A0A4D6HJY1
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

61858:DV706 RS08760
gene id: 61858:DV706_RS08760
uniprot id: A0A4D6HLU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

61858:DV706 RS10830
gene id: 61858:DV706_RS10830
uniprot id: A0A4D6HM78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS04275
gene id: 61858:DV706_RS04275
uniprot id: A0A4D6HHV5
names: Similarity
messages: Belongs to the AOR/FOR family.

61858:DV706 RS01135
gene id: 61858:DV706_RS01135
uniprot id: A0A4D6HR80
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

61858:DV706 RS19540
gene id: 61858:DV706_RS19540
uniprot id: A0A4D6HS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61858:DV706 RS00340
gene id: 61858:DV706_RS00340
uniprot id: A0A4D6HGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

61858:DV706 RS02775
gene id: 61858:DV706_RS02775
uniprot id: A0A4D6HH35
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

61858:DV706 RS01900
gene id: 61858:DV706_RS01900
uniprot id: A0A4D6HHJ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

61858:DV706 RS01695
gene id: 61858:DV706_RS01695
uniprot id: A0A4D6HGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

61858:DV706 RS06535
gene id: 61858:DV706_RS06535
uniprot id: A0A4D6HKT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

61858:DV706 RS19410
gene id: 61858:DV706_RS19410
uniprot id: A0A4D6HT61
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

61858:DV706 RS10740
gene id: 61858:DV706_RS10740
uniprot id: A0A4D6HPC7
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS11350
gene id: 61858:DV706_RS11350
uniprot id: A0A4D6HQS9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

61858:DV706 RS05265
gene id: 61858:DV706_RS05265
uniprot id: A0A4D6HJB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

61858:DV706 RS01715
gene id: 61858:DV706_RS01715
uniprot id: A0A4D6HJ57
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS09990
gene id: 61858:DV706_RS09990
uniprot id: A0A4D6HLQ3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

61858:DV706 RS00925
gene id: 61858:DV706_RS00925
uniprot id: A0A4D6HRD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS16545
gene id: 61858:DV706_RS16545
uniprot id: A0A4D6HGI0
names: Similarity
messages: Belongs to the arginase family.

61858:DV706 RS07980
gene id: 61858:DV706_RS07980
uniprot id: A0A4D6HMN7
names: Similarity
messages: Belongs to the TFIIB family.

61858:DV706 RS14525
gene id: 61858:DV706_RS14525
uniprot id: A0A4D6HQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS07495
gene id: 61858:DV706_RS07495
uniprot id: A0A4D6HJH2
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS14570
gene id: 61858:DV706_RS14570
uniprot id: A0A4D6HQT6
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

61858:DV706 RS04630
gene id: 61858:DV706_RS04630
uniprot id: A0A4D6HKU5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

61858:DV706 RS00430
gene id: 61858:DV706_RS00430
uniprot id: A0A4D6HIF1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

61858:DV706 RS14405
gene id: 61858:DV706_RS14405
uniprot id: A0A4D6HPR2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

61858:DV706 RS00260
gene id: 61858:DV706_RS00260
uniprot id: A0A4D6HQD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS08710
gene id: 61858:DV706_RS08710
uniprot id: A0A4D6HNC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61858:DV706 RS00500
gene id: 61858:DV706_RS00500
uniprot id: A0A4D6HJ80
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS01425
gene id: 61858:DV706_RS01425
uniprot id: A0A4D6HJN3
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

61858:DV706 RS07935
gene id: 61858:DV706_RS07935
uniprot id: A0A4D6HN17
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

61858:DV706 RS09610
gene id: 61858:DV706_RS09610
uniprot id: A0A4D6HKH0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

61858:DV706 RS01280
gene id: 61858:DV706_RS01280
uniprot id: A0A4D6HQ56
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS05645
gene id: 61858:DV706_RS05645
uniprot id: A0A4D6HSJ0
names: Similarity
messages: Belongs to the asparaginase 1 family.

61858:DV706 RS01910
gene id: 61858:DV706_RS01910
uniprot id: A0A4D6HII9
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07420
gene id: 61858:DV706_RS07420
uniprot id: A0A4D6HLA3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

61858:DV706 RS20935
gene id: 61858:DV706_RS20935
uniprot id: A0A4D6HV09
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS03590
gene id: 61858:DV706_RS03590
uniprot id: A0A4D6HIN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

61858:DV706 RS07520
gene id: 61858:DV706_RS07520
uniprot id: A0A4D6HK78
names: Similarity
messages: Belongs to the SUI1 family.

61858:DV706 RS06835
gene id: 61858:DV706_RS06835
uniprot id: A0A4D6HJ66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS15940
gene id: 61858:DV706_RS15940
uniprot id: A0A4D6HGX7
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

61858:DV706 RS16005
gene id: 61858:DV706_RS16005
uniprot id: A0A4D6HR80
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

61858:DV706 RS19420
gene id: 61858:DV706_RS19420
uniprot id: A0A4D6HS99
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

61858:DV706 RS04635
gene id: 61858:DV706_RS04635
uniprot id: A0A4D6HM86
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

61858:DV706 RS08945
gene id: 61858:DV706_RS08945
uniprot id: A0A4D6HNF9
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05170
gene id: 61858:DV706_RS05170
uniprot id: A0A4D6HMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

61858:DV706 RS16770
gene id: 61858:DV706_RS16770
uniprot id: A0A4D6HQB0
names: Similarity
messages: Belongs to the UPF0045 family.

61858:DV706 RS05100
gene id: 61858:DV706_RS05100
uniprot id: A0A4D6HJ85
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

61858:DV706 RS19110
gene id: 61858:DV706_RS19110
uniprot id: A0A4D6HRJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

61858:DV706 RS07115
gene id: 61858:DV706_RS07115
uniprot id: A0A4D6HKB5
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

61858:DV706 RS11575
gene id: 61858:DV706_RS11575
uniprot id: A0A4D6HPC6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

61858:DV706 RS16605
gene id: 61858:DV706_RS16605
uniprot id: A0A4D6HGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

61858:DV706 RS12055
gene id: 61858:DV706_RS12055
uniprot id: A0A4D6HMI5
names: Similarity
messages: Belongs to the glutaredoxin family.

61858:DV706 RS04340
gene id: 61858:DV706_RS04340
uniprot id: A0A4D6HKP8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS08975
gene id: 61858:DV706_RS08975
uniprot id: A0A4D6HMV9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

61858:DV706 RS00470
gene id: 61858:DV706_RS00470
uniprot id: A0A4D6HRN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS02700
gene id: 61858:DV706_RS02700
uniprot id: A0A4D6HHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61858:DV706 RS03350
gene id: 61858:DV706_RS03350
uniprot id: A0A4D6HHC4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

61858:DV706 RS16350
gene id: 61858:DV706_RS16350
uniprot id: A0A4D6HJC2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

61858:DV706 RS17050
gene id: 61858:DV706_RS17050
uniprot id: A0A4D6HGW0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS08780
gene id: 61858:DV706_RS08780
uniprot id: A0A4D6HNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61858:DV706 RS04700
gene id: 61858:DV706_RS04700
uniprot id: A0A4D6HJ65
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS09420
gene id: 61858:DV706_RS09420
uniprot id: A0A4D6HLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

61858:DV706 RS07750
gene id: 61858:DV706_RS07750
uniprot id: A0A4D6HKC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

61858:DV706 RS14575
gene id: 61858:DV706_RS14575
uniprot id: A0A4D6HS53
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS14200
gene id: 61858:DV706_RS14200
uniprot id: A0A4D6HR08
names: Similarity
messages: Belongs to the TPP enzyme family.

61858:DV706 RS05725
gene id: 61858:DV706_RS05725
uniprot id: A0A4D6HJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

61858:DV706 RS11885
gene id: 61858:DV706_RS11885
uniprot id: A0A4D6HLQ5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

61858:DV706 RS09215
gene id: 61858:DV706_RS09215
uniprot id: A0A4D6HLB1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

61858:DV706 RS13505
gene id: 61858:DV706_RS13505
uniprot id: A0A4D6HN88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS16570
gene id: 61858:DV706_RS16570
uniprot id: A0A4D6HHT6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

61858:DV706 RS11655
gene id: 61858:DV706_RS11655
uniprot id: A0A4D6HMB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

61858:DV706 RS08795
gene id: 61858:DV706_RS08795
uniprot id: A0A4D6HM28
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

61858:DV706 RS08155
gene id: 61858:DV706_RS08155
uniprot id: A0A4D6HL13
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

61858:DV706 RS20165
gene id: 61858:DV706_RS20165
uniprot id: A0A4D6HSB7
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

61858:DV706 RS17400
gene id: 61858:DV706_RS17400
uniprot id: A0A4D6HS05
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

61858:DV706 RS16640
gene id: 61858:DV706_RS16640
uniprot id: A0A4D6HJ80
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

61858:DV706 RS12645
gene id: 61858:DV706_RS12645
uniprot id: A0A4D6HP37
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

61858:DV706 RS03950
gene id: 61858:DV706_RS03950
uniprot id: A0A4D6HKV6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

61858:DV706 RS00090
gene id: 61858:DV706_RS00090
uniprot id: A0A4D6HGW0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07310
gene id: 61858:DV706_RS07310
uniprot id: A0A4D6HL85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS04615
gene id: 61858:DV706_RS04615
uniprot id: A0A4D6HIY8
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

61858:DV706 RS09685
gene id: 61858:DV706_RS09685
uniprot id: A0A4D6HSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

61858:DV706 RS01435
gene id: 61858:DV706_RS01435
uniprot id: A0A4D6HQY6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

61858:DV706 RS16665
gene id: 61858:DV706_RS16665
uniprot id: A0A4D6HJZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

61858:DV706 RS03715
gene id: 61858:DV706_RS03715
uniprot id: A0A4D6HJ86
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

61858:DV706 RS10080
gene id: 61858:DV706_RS10080
uniprot id: A0A4D6HQ61
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS07410
gene id: 61858:DV706_RS07410
uniprot id: A0A4D6HK59
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

61858:DV706 RS17080
gene id: 61858:DV706_RS17080
uniprot id: A0A4D6HHI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

61858:DV706 RS13465
gene id: 61858:DV706_RS13465
uniprot id: A0A4D6HQQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS09565
gene id: 61858:DV706_RS09565
uniprot id: A0A4D6HMF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS04985
gene id: 61858:DV706_RS04985
uniprot id: A0A4D6HIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

61858:DV706 RS09935
gene id: 61858:DV706_RS09935
uniprot id: A0A4D6HLP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

61858:DV706 RS09880
gene id: 61858:DV706_RS09880
uniprot id: A0A4D6HNG5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

61858:DV706 RS12260
gene id: 61858:DV706_RS12260
uniprot id: A0A4D6HNR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

61858:DV706 RS07880
gene id: 61858:DV706_RS07880
uniprot id: A0A4D6HLH7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

61858:DV706 RS03125
gene id: 61858:DV706_RS03125
uniprot id: A0A4D6HH88
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS00320
gene id: 61858:DV706_RS00320
uniprot id: A0A4D6HGB7
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

61858:DV706 RS04270
gene id: 61858:DV706_RS04270
uniprot id: A0A4D6HIS9
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS14680
gene id: 61858:DV706_RS14680
uniprot id: A0A4D6HN87
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

61858:DV706 RS01540
gene id: 61858:DV706_RS01540
uniprot id: A0A4D6HH42
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS19620
gene id: 61858:DV706_RS19620
uniprot id: A0A4D6HTJ4
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

61858:DV706 RS14260
gene id: 61858:DV706_RS14260
uniprot id: A0A4D6HN19
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

61858:DV706 RS20840
gene id: 61858:DV706_RS20840
uniprot id: A0A4D6HVA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS06650
gene id: 61858:DV706_RS06650
uniprot id: A0A4D6HKV4
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

61858:DV706 RS20060
gene id: 61858:DV706_RS20060
uniprot id: A0A4D6HTP9
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10285
gene id: 61858:DV706_RS10285
uniprot id: A0A4D6HP45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS01200
gene id: 61858:DV706_RS01200
uniprot id: A0A4D6HGX7
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

61858:DV706 RS00600
gene id: 61858:DV706_RS00600
uniprot id: A0A4D6HTI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS13665
gene id: 61858:DV706_RS13665
uniprot id: A0A4D6HNB4
names: Similarity
messages: Belongs to the peptidase C56 family.

61858:DV706 RS00045
gene id: 61858:DV706_RS00045
uniprot id: A0A4D6HS82
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

61858:DV706 RS08185
gene id: 61858:DV706_RS08185
uniprot id: A0A4D6HLS5
names: Similarity
messages: Belongs to the MoaB/Mog family.

61858:DV706 RS06605
gene id: 61858:DV706_RS06605
uniprot id: A0A4D6HJ26
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

61858:DV706 RS03540
gene id: 61858:DV706_RS03540
uniprot id: A0A4D6HIN1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

61858:DV706 RS05675
gene id: 61858:DV706_RS05675
uniprot id: A0A4D6HJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

61858:DV706 RS00595
gene id: 61858:DV706_RS00595
uniprot id: A0A4D6HGI0
names: Similarity
messages: Belongs to the arginase family.

61858:DV706 RS01335
gene id: 61858:DV706_RS01335
uniprot id: A0A4D6HIA3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

61858:DV706 RS16590
gene id: 61858:DV706_RS16590
uniprot id: A0A4D6HRZ0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61858:DV706 RS06985
gene id: 61858:DV706_RS06985
uniprot id: A0A4D6HL26
names: Similarity
messages: Belongs to the peptidase M20A family.

61858:DV706 RS15115
gene id: 61858:DV706_RS15115
uniprot id: A0A4D6HQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

61858:DV706 RS09160
gene id: 61858:DV706_RS09160
uniprot id: A0A4D6HL98
names: Similarity
messages: Belongs to the peptidase S9C family.

61858:DV706 RS10660
gene id: 61858:DV706_RS10660
uniprot id: A0A4D6HNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

61858:DV706 RS03585
gene id: 61858:DV706_RS03585
uniprot id: A0A4D6HI42
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS04230
gene id: 61858:DV706_RS04230
uniprot id: A0A4D6HKM7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

61858:DV706 RS20430
gene id: 61858:DV706_RS20430
uniprot id: A0A4D6HT55
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

61858:DV706 RS13590
gene id: 61858:DV706_RS13590
uniprot id: A0A4D6HMN6
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03460
gene id: 61858:DV706_RS03460
uniprot id: A0A4D6HHE6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

61858:DV706 RS11145
gene id: 61858:DV706_RS11145
uniprot id: A0A4D6HM23
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

61858:DV706 RS11775
gene id: 61858:DV706_RS11775
uniprot id: A0A4D6HPX4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

61858:DV706 RS16675
gene id: 61858:DV706_RS16675
uniprot id: A0A4D6HSS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS11915
gene id: 61858:DV706_RS11915
uniprot id: A0A4D6HMH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

61858:DV706 RS16050
gene id: 61858:DV706_RS16050
uniprot id: A0A4D6HQI9
names: Similarity
messages: Belongs to the peptidase S49 family.

61858:DV706 RS19910
gene id: 61858:DV706_RS19910
uniprot id: A0A4D6HUS3
names: Similarity
messages: Belongs to the SCO1/2 family.

61858:DV706 RS02815
gene id: 61858:DV706_RS02815
uniprot id: A0A4D6HIB3
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS12715
gene id: 61858:DV706_RS12715
uniprot id: A0A4D6HMV5
names: Similarity
messages: Belongs to the BtpA family.

61858:DV706 RS14880
gene id: 61858:DV706_RS14880
uniprot id: A0A4D6HRA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61858:DV706 RS15890
gene id: 61858:DV706_RS15890
uniprot id: A0A4D6HGZ5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

61858:DV706 RS06245
gene id: 61858:DV706_RS06245
uniprot id: A0A4D6HN84
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

61858:DV706 RS07990
gene id: 61858:DV706_RS07990
uniprot id: A0A4D6HKG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61858:DV706 RS11865
gene id: 61858:DV706_RS11865
uniprot id: A0A4D6HMS8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

61858:DV706 RS00070
gene id: 61858:DV706_RS00070
uniprot id: A0A4D6HRA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS09170
gene id: 61858:DV706_RS09170
uniprot id: A0A4D6HM89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

61858:DV706 RS10980
gene id: 61858:DV706_RS10980
uniprot id: A0A4D6HNZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

61858:DV706 RS21080
gene id: 61858:DV706_RS21080
uniprot id: A0A4D6HU67
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS05660
gene id: 61858:DV706_RS05660
uniprot id: A0A4D6HMV0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

61858:DV706 RS19125
gene id: 61858:DV706_RS19125
uniprot id: A0A4D6HUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

61858:DV706 RS00825
gene id: 61858:DV706_RS00825
uniprot id: A0A4D6HGP3
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

61858:DV706 RS14610
gene id: 61858:DV706_RS14610
uniprot id: A0A4D6HS04
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

61858:DV706 RS07675
gene id: 61858:DV706_RS07675
uniprot id: A0A4D6HLJ9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

61858:DV706 RS16735
gene id: 61858:DV706_RS16735
uniprot id: A0A4D6HQA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

61858:DV706 RS10350
gene id: 61858:DV706_RS10350
uniprot id: A0A4D6HLV4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

61858:DV706 RS14910
gene id: 61858:DV706_RS14910
uniprot id: A0A4D6HS94
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

61858:DV706 RS07135
gene id: 61858:DV706_RS07135
uniprot id: A0A4D6HM03
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

61858:DV706 RS12170
gene id: 61858:DV706_RS12170
uniprot id: A0A4D6HLW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS20315
gene id: 61858:DV706_RS20315
uniprot id: A0A4D6HTQ9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

61858:DV706 RS07765
gene id: 61858:DV706_RS07765
uniprot id: A0A4D6HMZ2
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

61858:DV706 RS11975
gene id: 61858:DV706_RS11975
uniprot id: A0A4D6HMI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

61858:DV706 RS14855
gene id: 61858:DV706_RS14855
uniprot id: A0A4D6HS87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS19500
gene id: 61858:DV706_RS19500
uniprot id: A0A4D6HSN9
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

61858:DV706 RS09480
gene id: 61858:DV706_RS09480
uniprot id: A0A4D6HL70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

61858:DV706 RS11705
gene id: 61858:DV706_RS11705
uniprot id: A0A4D6HPF9
names: Similarity
messages: Belongs to the PEPCase type 1 family.

61858:DV706 RS00410
gene id: 61858:DV706_RS00410
uniprot id: A0A4D6HG62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

61858:DV706 RS12790
gene id: 61858:DV706_RS12790
uniprot id: A0A4D6HMW3
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

61858:DV706 RS12675
gene id: 61858:DV706_RS12675
uniprot id: A0A4D6HMU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

61858:DV706 RS07685
gene id: 61858:DV706_RS07685
uniprot id: A0A4D6HP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

61858:DV706 RS16885
gene id: 61858:DV706_RS16885
uniprot id: A0A4D6HJW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS07480
gene id: 61858:DV706_RS07480
uniprot id: A0A4D6HLA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS05435
gene id: 61858:DV706_RS05435
uniprot id: A0A4D6HMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

61858:DV706 RS13065
gene id: 61858:DV706_RS13065
uniprot id: A0A4D6HP52
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS03145
gene id: 61858:DV706_RS03145
uniprot id: A0A4D6HR83
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS01405
gene id: 61858:DV706_RS01405
uniprot id: A0A4D6HJ07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS17880
gene id: 61858:DV706_RS17880
uniprot id: A0A4D6HSJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS13420
gene id: 61858:DV706_RS13420
uniprot id: A0A4D6HN63
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

61858:DV706 RS05630
gene id: 61858:DV706_RS05630
uniprot id: A0A4D6HLT0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

61858:DV706 RS13095
gene id: 61858:DV706_RS13095
uniprot id: A0A4D6HQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

61858:DV706 RS16695
gene id: 61858:DV706_RS16695
uniprot id: A0A4D6HSJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

61858:DV706 RS20110
gene id: 61858:DV706_RS20110
uniprot id: A0A4D6HSA5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS02120
gene id: 61858:DV706_RS02120
uniprot id: A0A4D6HHN6
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS11605
gene id: 61858:DV706_RS11605
uniprot id: A0A4D6HMA9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

61858:DV706 RS04605
gene id: 61858:DV706_RS04605
uniprot id: A0A4D6HJR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

61858:DV706 RS06160
gene id: 61858:DV706_RS06160
uniprot id: A0A4D6HKR5
names: Similarity
messages: Belongs to the SUI1 family.

61858:DV706 RS06565
gene id: 61858:DV706_RS06565
uniprot id: A0A4D6HLT4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

61858:DV706 RS11835
gene id: 61858:DV706_RS11835
uniprot id: A0A4D6HLP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS13480
gene id: 61858:DV706_RS13480
uniprot id: A0A4D6HPP5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

61858:DV706 RS00335
gene id: 61858:DV706_RS00335
uniprot id: A0A4D6HJ51
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

61858:DV706 RS16700
gene id: 61858:DV706_RS16700
uniprot id: A0A4D6HTM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS11905
gene id: 61858:DV706_RS11905
uniprot id: A0A4D6HR39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

61858:DV706 RS19120
gene id: 61858:DV706_RS19120
uniprot id: A0A4D6HTN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS09570
gene id: 61858:DV706_RS09570
uniprot id: A0A4D6HN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS11880
gene id: 61858:DV706_RS11880
uniprot id: A0A4D6HMF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

61858:DV706 RS11895
gene id: 61858:DV706_RS11895
uniprot id: A0A4D6HPJ7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

61858:DV706 RS12570
gene id: 61858:DV706_RS12570
uniprot id: A0A4D6HRG1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

61858:DV706 RS11180
gene id: 61858:DV706_RS11180
uniprot id: A0A4D6HP40
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

61858:DV706 RS00705
gene id: 61858:DV706_RS00705
uniprot id: A0A4D6HK40
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

61858:DV706 RS10885
gene id: 61858:DV706_RS10885
uniprot id: A0A4D6HM88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS11060
gene id: 61858:DV706_RS11060
uniprot id: A0A4D6HM30
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS10190
gene id: 61858:DV706_RS10190
uniprot id: A0A4D6HLS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

61858:DV706 RS07655
gene id: 61858:DV706_RS07655
uniprot id: A0A4D6HLD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS14650
gene id: 61858:DV706_RS14650
uniprot id: A0A4D6HNR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61858:DV706 RS02715
gene id: 61858:DV706_RS02715
uniprot id: A0A4D6HKB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

61858:DV706 RS08645
gene id: 61858:DV706_RS08645
uniprot id: A0A4D6HL77
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

61858:DV706 RS17105
gene id: 61858:DV706_RS17105
uniprot id: A0A4D6HTT8
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS15095
gene id: 61858:DV706_RS15095
uniprot id: A0A4D6HQ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

61858:DV706 RS14640
gene id: 61858:DV706_RS14640
uniprot id: A0A4D6HS60
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

61858:DV706 RS14530
gene id: 61858:DV706_RS14530
uniprot id: A0A4D6HNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS16015
gene id: 61858:DV706_RS16015
uniprot id: A0A4D6HQ92
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

61858:DV706 RS11820
gene id: 61858:DV706_RS11820
uniprot id: A0A4D6HNG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS16720
gene id: 61858:DV706_RS16720
uniprot id: A0A4D6HIQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

61858:DV706 RS00455
gene id: 61858:DV706_RS00455
uniprot id: A0A4D6HQ82
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

61858:DV706 RS16610
gene id: 61858:DV706_RS16610
uniprot id: A0A4D6HIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

61858:DV706 RS07435
gene id: 61858:DV706_RS07435
uniprot id: A0A4D6HR74
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

61858:DV706 RS15660
gene id: 61858:DV706_RS15660
uniprot id: A0A4D6HHQ8
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

61858:DV706 RS09025
gene id: 61858:DV706_RS09025
uniprot id: A0A4D6HMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

61858:DV706 RS07215
gene id: 61858:DV706_RS07215
uniprot id: A0A4D6HKL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

61858:DV706 RS05995
gene id: 61858:DV706_RS05995
uniprot id: A0A4D6HLG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61858:DV706 RS05390
gene id: 61858:DV706_RS05390
uniprot id: A0A4D6HL80
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS14795
gene id: 61858:DV706_RS14795
uniprot id: A0A4D6HQW7
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS12565
gene id: 61858:DV706_RS12565
uniprot id: A0A4D6HQ00
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

61858:DV706 RS07230
gene id: 61858:DV706_RS07230
uniprot id: A0A4D6HKC9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

61858:DV706 RS04390
gene id: 61858:DV706_RS04390
uniprot id: A0A4D6HJT3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

61858:DV706 RS07040
gene id: 61858:DV706_RS07040
uniprot id: A0A4D6HL36
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS06715
gene id: 61858:DV706_RS06715
uniprot id: A0A4D6HMG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS05165
gene id: 61858:DV706_RS05165
uniprot id: A0A4D6HL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

61858:DV706 RS11920
gene id: 61858:DV706_RS11920
uniprot id: A0A4D6HMT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

61858:DV706 RS15595
gene id: 61858:DV706_RS15595
uniprot id: A0A4D6HHR7
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS04795
gene id: 61858:DV706_RS04795
uniprot id: A0A4D6HKW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

61858:DV706 RS05000
gene id: 61858:DV706_RS05000
uniprot id: A0A4D6HQQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS09560
gene id: 61858:DV706_RS09560
uniprot id: A0A4D6HKG0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS06720
gene id: 61858:DV706_RS06720
uniprot id: A0A4D6HK49
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS00790
gene id: 61858:DV706_RS00790
uniprot id: A0A4D6HJC2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

61858:DV706 RS10345
gene id: 61858:DV706_RS10345
uniprot id: A0A4D6HP56
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS18850
gene id: 61858:DV706_RS18850
uniprot id: A0A4D6HRD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

61858:DV706 RS20155
gene id: 61858:DV706_RS20155
uniprot id: A0A4D6HUN5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

61858:DV706 RS00065
gene id: 61858:DV706_RS00065
uniprot id: A0A4D6HRV9
names: Similarity
messages: Belongs to the TrpF family.

61858:DV706 RS13425
gene id: 61858:DV706_RS13425
uniprot id: A0A4D6HML0
names: Subcellular Location Annotation
messages: Membrane

61858:DV706 RS00080
gene id: 61858:DV706_RS00080
uniprot id: A0A4D6HQH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

61858:DV706 RS14345
gene id: 61858:DV706_RS14345
uniprot id: A0A4D6HNN2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

61858:DV706 RS16215
gene id: 61858:DV706_RS16215
uniprot id: A0A4D6HRD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

61858:DV706 RS12105
gene id: 61858:DV706_RS12105
uniprot id: A0A4D6HQ43
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

61858:DV706 RS00420
gene id: 61858:DV706_RS00420
uniprot id: A0A4D6HIQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

61858:DV706 RS12515
gene id: 61858:DV706_RS12515
uniprot id: A0A4D6HPZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

61858:DV706 RS06875
gene id: 61858:DV706_RS06875
uniprot id: A0A4D6HL06
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61858:DV706 RS19550
gene id: 61858:DV706_RS19550
uniprot id: A0A4D6HT88
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

61858:DV706 RS11995
gene id: 61858:DV706_RS11995
uniprot id: A0A4D6HMH5
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

61858:DV706 RS16505
gene id: 61858:DV706_RS16505
uniprot id: A0A4D6HIV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

61858:DV706 RS02845
gene id: 61858:DV706_RS02845
uniprot id: A0A4D6HJ10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61858:DV706 RS16450
gene id: 61858:DV706_RS16450
uniprot id: A0A4D6HHV3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

61858:DV706 RS17805
gene id: 61858:DV706_RS17805
uniprot id: A0A4D6HQW4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

61858:DV706 RS03225
gene id: 61858:DV706_RS03225
uniprot id: A0A4D6HII2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

61858:DV706 RS16880
gene id: 61858:DV706_RS16880
uniprot id: A0A4D6HQD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61858:DV706 RS00620
gene id: 61858:DV706_RS00620
uniprot id: A0A4D6HQM4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

61858:DV706 RS12530
gene id: 61858:DV706_RS12530
uniprot id: A0A4D6HMS7
names: Similarity
messages: Belongs to the UPF0440 family.

61858:DV706 RS05815
gene id: 61858:DV706_RS05815
uniprot id: A0A4D6HPF8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS11815
gene id: 61858:DV706_RS11815
uniprot id: A0A4D6HMR0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

61858:DV706 RS13315
gene id: 61858:DV706_RS13315
uniprot id: A0A4D6HN43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61858:DV706 RS08980
gene id: 61858:DV706_RS08980
uniprot id: A0A4D6HPN2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

61858:DV706 RS10045
gene id: 61858:DV706_RS10045
uniprot id: A0A4D6HLQ9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

61858:DV706 RS09465
gene id: 61858:DV706_RS09465
uniprot id: A0A4D6HN33
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.