61635:BN853 RS03370
gene id: 61635:BN853_RS03370
uniprot id: U4KN74
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS00935
gene id: 61635:BN853_RS00935
uniprot id: U4KQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

61635:BN853 RS05160
gene id: 61635:BN853_RS05160
uniprot id: U4KNS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

61635:BN853 RS06075
gene id: 61635:BN853_RS06075
uniprot id: U4KP60
names: Similarity
messages: Belongs to the DtxR/MntR family.

61635:BN853 RS05420
gene id: 61635:BN853_RS05420
uniprot id: U4KT53
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

61635:BN853 RS05890
gene id: 61635:BN853_RS05890
uniprot id: U4KPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS08225
gene id: 61635:BN853_RS08225
uniprot id: U4KQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

61635:BN853 RS06660
gene id: 61635:BN853_RS06660
uniprot id: U4KS55
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS00850
gene id: 61635:BN853_RS00850
uniprot id: U4KMD5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS02260
gene id: 61635:BN853_RS02260
uniprot id: U4KR65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS05450
gene id: 61635:BN853_RS05450
uniprot id: U4KP32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

61635:BN853 RS08420
gene id: 61635:BN853_RS08420
uniprot id: U4KQD5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS04255
gene id: 61635:BN853_RS04255
uniprot id: U4KNK6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS01380
gene id: 61635:BN853_RS01380
uniprot id: U4KMD2
names: Similarity
messages: Belongs to the thioredoxin family.

61635:BN853 RS04225
gene id: 61635:BN853_RS04225
uniprot id: U4KNJ5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

61635:BN853 RS01650
gene id: 61635:BN853_RS01650
uniprot id: U4KML1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

61635:BN853 RS06405
gene id: 61635:BN853_RS06405
uniprot id: U4KT92
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS03030
gene id: 61635:BN853_RS03030
uniprot id: U4KRB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

61635:BN853 RS01300
gene id: 61635:BN853_RS01300
uniprot id: U4KMC2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

61635:BN853 RS07870
gene id: 61635:BN853_RS07870
uniprot id: U4KSD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

61635:BN853 RS06920
gene id: 61635:BN853_RS06920
uniprot id: U4KPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS04610
gene id: 61635:BN853_RS04610
uniprot id: U4KNL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

61635:BN853 RS07075
gene id: 61635:BN853_RS07075
uniprot id: U4KPL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

61635:BN853 RS06515
gene id: 61635:BN853_RS06515
uniprot id: U4KPM3
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06095
gene id: 61635:BN853_RS06095
uniprot id: U4KPF5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

61635:BN853 RS02925
gene id: 61635:BN853_RS02925
uniprot id: U4KRB0
names: Similarity
messages: Belongs to the CvfB family.

61635:BN853 RS03055
gene id: 61635:BN853_RS03055
uniprot id: U4KRC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

61635:BN853 RS07145
gene id: 61635:BN853_RS07145
uniprot id: U4KPY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS07985
gene id: 61635:BN853_RS07985
uniprot id: U4KSE3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61635:BN853 RS08660
gene id: 61635:BN853_RS08660
uniprot id: U4KTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS01450
gene id: 61635:BN853_RS01450
uniprot id: U4KMI9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

61635:BN853 RS08455
gene id: 61635:BN853_RS08455
uniprot id: U4KQ59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS08320
gene id: 61635:BN853_RS08320
uniprot id: U4KQC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

61635:BN853 RS07960
gene id: 61635:BN853_RS07960
uniprot id: U4KSE1
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

61635:BN853 RS07180
gene id: 61635:BN853_RS07180
uniprot id: U4KS96
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

61635:BN853 RS06630
gene id: 61635:BN853_RS06630
uniprot id: U4KPE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

61635:BN853 RS04670
gene id: 61635:BN853_RS04670
uniprot id: U4KT23
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

61635:BN853 RS05840
gene id: 61635:BN853_RS05840
uniprot id: U4KPB4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

61635:BN853 RS06305
gene id: 61635:BN853_RS06305
uniprot id: U4KS25
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS03900
gene id: 61635:BN853_RS03900
uniprot id: U4KNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

61635:BN853 RS08310
gene id: 61635:BN853_RS08310
uniprot id: U4KSG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

61635:BN853 RS00075
gene id: 61635:BN853_RS00075
uniprot id: U4KM38
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

61635:BN853 RS03975
gene id: 61635:BN853_RS03975
uniprot id: U4KNF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS05240
gene id: 61635:BN853_RS05240
uniprot id: U4KRT6
names: Similarity
messages: Belongs to the UPF0473 family.

61635:BN853 RS03330
gene id: 61635:BN853_RS03330
uniprot id: U4KRE3
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

61635:BN853 RS01890
gene id: 61635:BN853_RS01890
uniprot id: U4KSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

61635:BN853 RS02975
gene id: 61635:BN853_RS02975
uniprot id: U4KRB4
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

61635:BN853 RS00120
gene id: 61635:BN853_RS00120
uniprot id: U4KM19
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

61635:BN853 RS07170
gene id: 61635:BN853_RS07170
uniprot id: U4KPY5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

61635:BN853 RS03270
gene id: 61635:BN853_RS03270
uniprot id: U4KN58
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

61635:BN853 RS00915
gene id: 61635:BN853_RS00915
uniprot id: U4KSM9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

61635:BN853 RS08605
gene id: 61635:BN853_RS08605
uniprot id: U4KQ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

61635:BN853 RS03140
gene id: 61635:BN853_RS03140
uniprot id: U4KN26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

61635:BN853 RS05215
gene id: 61635:BN853_RS05215
uniprot id: U4KRT4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

61635:BN853 RS04395
gene id: 61635:BN853_RS04395
uniprot id: U4KT12
names: Similarity
messages: Belongs to the peptidase M24B family.

61635:BN853 RS04960
gene id: 61635:BN853_RS04960
uniprot id: U4KNQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

61635:BN853 RS06980
gene id: 61635:BN853_RS06980
uniprot id: U4KS75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

61635:BN853 RS06945
gene id: 61635:BN853_RS06945
uniprot id: U4KPS9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

61635:BN853 RS01305
gene id: 61635:BN853_RS01305
uniprot id: U4KQY9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

61635:BN853 RS07415
gene id: 61635:BN853_RS07415
uniprot id: U4KQ17
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

61635:BN853 RS02945
gene id: 61635:BN853_RS02945
uniprot id: U4KMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

61635:BN853 RS05100
gene id: 61635:BN853_RS05100
uniprot id: U4KNY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

61635:BN853 RS05425
gene id: 61635:BN853_RS05425
uniprot id: U4KP28
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

61635:BN853 RS02065
gene id: 61635:BN853_RS02065
uniprot id: U4KMP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS03195
gene id: 61635:BN853_RS03195
uniprot id: U4KN47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

61635:BN853 RS06460
gene id: 61635:BN853_RS06460
uniprot id: U4KPJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61635:BN853 RS08465
gene id: 61635:BN853_RS08465
uniprot id: U4KTH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

61635:BN853 RS03415
gene id: 61635:BN853_RS03415
uniprot id: U4KN66
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

61635:BN853 RS03190
gene id: 61635:BN853_RS03190
uniprot id: U4KN32
names: Similarity
messages: Belongs to the peptidase S41A family.

61635:BN853 RS08415
gene id: 61635:BN853_RS08415
uniprot id: U4KTG8
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

61635:BN853 RS00090
gene id: 61635:BN853_RS00090
uniprot id: U4KSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

61635:BN853 RS02550
gene id: 61635:BN853_RS02550
uniprot id: U4KMS2
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

61635:BN853 RS08000
gene id: 61635:BN853_RS08000
uniprot id: U4KQ91
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

61635:BN853 RS01695
gene id: 61635:BN853_RS01695
uniprot id: U4KMK0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

61635:BN853 RS01925
gene id: 61635:BN853_RS01925
uniprot id: U4KMN8
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

61635:BN853 RS03655
gene id: 61635:BN853_RS03655
uniprot id: U4KRH0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

61635:BN853 RS03620
gene id: 61635:BN853_RS03620
uniprot id: U4KNB4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

61635:BN853 RS02875
gene id: 61635:BN853_RS02875
uniprot id: U4KRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS07585
gene id: 61635:BN853_RS07585
uniprot id: U4KQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

61635:BN853 RS03855
gene id: 61635:BN853_RS03855
uniprot id: U4KNE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

61635:BN853 RS08235
gene id: 61635:BN853_RS08235
uniprot id: U4KQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS02760
gene id: 61635:BN853_RS02760
uniprot id: U4KSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

61635:BN853 RS06065
gene id: 61635:BN853_RS06065
uniprot id: U4KPD0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

61635:BN853 RS02050
gene id: 61635:BN853_RS02050
uniprot id: U4KMQ0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

61635:BN853 RS06335
gene id: 61635:BN853_RS06335
uniprot id: U4KT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS01340
gene id: 61635:BN853_RS01340
uniprot id: U4KSP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

61635:BN853 RS00005
gene id: 61635:BN853_RS00005
uniprot id: U4KLW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

61635:BN853 RS06055
gene id: 61635:BN853_RS06055
uniprot id: U4KS04
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

61635:BN853 RS02355
gene id: 61635:BN853_RS02355
uniprot id: U4KMQ1
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06110
gene id: 61635:BN853_RS06110
uniprot id: U4KT80
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS03430
gene id: 61635:BN853_RS03430
uniprot id: U4KSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS06965
gene id: 61635:BN853_RS06965
uniprot id: U4KPR7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

61635:BN853 RS04935
gene id: 61635:BN853_RS04935
uniprot id: U4KNP9
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS07330
gene id: 61635:BN853_RS07330
uniprot id: U4KTC5
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS03640
gene id: 61635:BN853_RS03640
uniprot id: U4KNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

61635:BN853 RS02215
gene id: 61635:BN853_RS02215
uniprot id: U4KSS6
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS05265
gene id: 61635:BN853_RS05265
uniprot id: U4KRT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

61635:BN853 RS03345
gene id: 61635:BN853_RS03345
uniprot id: U4KN70
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

61635:BN853 RS02895
gene id: 61635:BN853_RS02895
uniprot id: U4KMW1
names: Subcellular Location Annotation
messages: Cytoplasm

61635:BN853 RS04280
gene id: 61635:BN853_RS04280
uniprot id: U4KNL0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

61635:BN853 RS08155
gene id: 61635:BN853_RS08155
uniprot id: U4KQB0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

61635:BN853 RS06435
gene id: 61635:BN853_RS06435
uniprot id: U4KPJ3
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS00810
gene id: 61635:BN853_RS00810
uniprot id: U4KM72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

61635:BN853 RS08115
gene id: 61635:BN853_RS08115
uniprot id: U4KTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

61635:BN853 RS00185
gene id: 61635:BN853_RS00185
uniprot id: U4KQR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

61635:BN853 RS00975
gene id: 61635:BN853_RS00975
uniprot id: U4KME8
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06205
gene id: 61635:BN853_RS06205
uniprot id: U4KS16
names: Function
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

61635:BN853 RS01400
gene id: 61635:BN853_RS01400
uniprot id: U4KMI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS01465
gene id: 61635:BN853_RS01465
uniprot id: U4KSP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS08215
gene id: 61635:BN853_RS08215
uniprot id: U4KSG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

61635:BN853 RS01255
gene id: 61635:BN853_RS01255
uniprot id: U4KSN8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

61635:BN853 RS06410
gene id: 61635:BN853_RS06410
uniprot id: U4KPI9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

61635:BN853 RS00945
gene id: 61635:BN853_RS00945
uniprot id: U4KMC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS01865
gene id: 61635:BN853_RS01865
uniprot id: U4KSR2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

61635:BN853 RS06780
gene id: 61635:BN853_RS06780
uniprot id: U4KS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

61635:BN853 RS08375
gene id: 61635:BN853_RS08375
uniprot id: U4KQD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

61635:BN853 RS05975
gene id: 61635:BN853_RS05975
uniprot id: U4KP43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS02835
gene id: 61635:BN853_RS02835
uniprot id: U4KN03
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06930
gene id: 61635:BN853_RS06930
uniprot id: U4KS71
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

61635:BN853 RS03800
gene id: 61635:BN853_RS03800
uniprot id: U4KNE1
names: Similarity
messages: Belongs to the YjdM family.

61635:BN853 RS02855
gene id: 61635:BN853_RS02855
uniprot id: U4KMZ2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

61635:BN853 RS02630
gene id: 61635:BN853_RS02630
uniprot id: U4KMW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

61635:BN853 RS02990
gene id: 61635:BN853_RS02990
uniprot id: U4KN08
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

61635:BN853 RS07515
gene id: 61635:BN853_RS07515
uniprot id: U4KQ31
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS03425
gene id: 61635:BN853_RS03425
uniprot id: U4KRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS01250
gene id: 61635:BN853_RS01250
uniprot id: U4KQY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

61635:BN853 RS07360
gene id: 61635:BN853_RS07360
uniprot id: U4KPY3
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS01640
gene id: 61635:BN853_RS01640
uniprot id: U4KSQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

61635:BN853 RS00745
gene id: 61635:BN853_RS00745
uniprot id: U4KSM2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

61635:BN853 RS05950
gene id: 61635:BN853_RS05950
uniprot id: U4KP39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

61635:BN853 RS03605
gene id: 61635:BN853_RS03605
uniprot id: U4KRG5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

61635:BN853 RS01360
gene id: 61635:BN853_RS01360
uniprot id: U4KQZ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

61635:BN853 RS01265
gene id: 61635:BN853_RS01265
uniprot id: U4KMG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

61635:BN853 RS01030
gene id: 61635:BN853_RS01030
uniprot id: U4KMA3
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS01945
gene id: 61635:BN853_RS01945
uniprot id: U4KMM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

61635:BN853 RS08355
gene id: 61635:BN853_RS08355
uniprot id: U4KQ46
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

61635:BN853 RS04555
gene id: 61635:BN853_RS04555
uniprot id: U4KNS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

61635:BN853 RS00085
gene id: 61635:BN853_RS00085
uniprot id: U4KQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

61635:BN853 RS02950
gene id: 61635:BN853_RS02950
uniprot id: U4KRB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

61635:BN853 RS02970
gene id: 61635:BN853_RS02970
uniprot id: U4KMX0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

61635:BN853 RS00035
gene id: 61635:BN853_RS00035
uniprot id: U4KQR2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS04680
gene id: 61635:BN853_RS04680
uniprot id: U4KNU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

61635:BN853 RS00195
gene id: 61635:BN853_RS00195
uniprot id: U4KM28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

61635:BN853 RS04115
gene id: 61635:BN853_RS04115
uniprot id: U4KRK6
names: Similarity
messages: Belongs to the NadC/ModD family.

61635:BN853 RS06960
gene id: 61635:BN853_RS06960
uniprot id: U4KTB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

61635:BN853 RS07115
gene id: 61635:BN853_RS07115
uniprot id: U4KPV7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

61635:BN853 RS07750
gene id: 61635:BN853_RS07750
uniprot id: U4KTE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS04340
gene id: 61635:BN853_RS04340
uniprot id: U4KRM5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

61635:BN853 RS03600
gene id: 61635:BN853_RS03600
uniprot id: U4KN49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

61635:BN853 RS07150
gene id: 61635:BN853_RS07150
uniprot id: U4KPP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS08295
gene id: 61635:BN853_RS08295
uniprot id: U4KQC0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

61635:BN853 RS01600
gene id: 61635:BN853_RS01600
uniprot id: U4KMK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

61635:BN853 RS02880
gene id: 61635:BN853_RS02880
uniprot id: U4KSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS03280
gene id: 61635:BN853_RS03280
uniprot id: U4KRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

61635:BN853 RS04645
gene id: 61635:BN853_RS04645
uniprot id: U4KT22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

61635:BN853 RS01810
gene id: 61635:BN853_RS01810
uniprot id: U4KR27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

61635:BN853 RS03840
gene id: 61635:BN853_RS03840
uniprot id: U4KRI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

61635:BN853 RS08515
gene id: 61635:BN853_RS08515
uniprot id: U4KTH2
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

61635:BN853 RS03180
gene id: 61635:BN853_RS03180
uniprot id: U4KRD0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

61635:BN853 RS02310
gene id: 61635:BN853_RS02310
uniprot id: U4KR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS03965
gene id: 61635:BN853_RS03965
uniprot id: U4KRJ4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS04440
gene id: 61635:BN853_RS04440
uniprot id: U4KRN3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

61635:BN853 RS03230
gene id: 61635:BN853_RS03230
uniprot id: U4KRD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

61635:BN853 RS01445
gene id: 61635:BN853_RS01445
uniprot id: U4KMH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

61635:BN853 RS08445
gene id: 61635:BN853_RS08445
uniprot id: U4KQD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

61635:BN853 RS04750
gene id: 61635:BN853_RS04750
uniprot id: U4KNS9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

61635:BN853 RS07340
gene id: 61635:BN853_RS07340
uniprot id: U4KQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61635:BN853 RS05095
gene id: 61635:BN853_RS05095
uniprot id: U4KT40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

61635:BN853 RS01770
gene id: 61635:BN853_RS01770
uniprot id: U4KMK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

61635:BN853 RS07575
gene id: 61635:BN853_RS07575
uniprot id: U4KSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS04515
gene id: 61635:BN853_RS04515
uniprot id: U4KRN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

61635:BN853 RS00885
gene id: 61635:BN853_RS00885
uniprot id: U4KQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

61635:BN853 RS00010
gene id: 61635:BN853_RS00010
uniprot id: U4KQR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA which binds and tethers DNA polymerases and other proteins to the DNA. The DNA replisome complex has a single clamp-loading complex (3 tau and 1 each of delta, delta', psi and chi subunits) which binds 3 Pol III cores (1 core on the leading strand and 2 on the lagging strand) each with a beta sliding clamp dimer. Additional proteins in the replisome are other copies of gamma, psi and chi, Ssb, DNA helicase and RNA primase.

61635:BN853 RS08600
gene id: 61635:BN853_RS08600
uniprot id: U4KQG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

61635:BN853 RS03160
gene id: 61635:BN853_RS03160
uniprot id: U4KSW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

61635:BN853 RS01275
gene id: 61635:BN853_RS01275
uniprot id: U4KQY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

61635:BN853 RS06165
gene id: 61635:BN853_RS06165
uniprot id: U4KPF0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

61635:BN853 RS07665
gene id: 61635:BN853_RS07665
uniprot id: U4KPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS04505
gene id: 61635:BN853_RS04505
uniprot id: U4KNP8
names: Similarity
messages: Belongs to the asparaginase 1 family.

61635:BN853 RS07755
gene id: 61635:BN853_RS07755
uniprot id: U4KQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS05300
gene id: 61635:BN853_RS05300
uniprot id: U4KP08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

61635:BN853 RS03275
gene id: 61635:BN853_RS03275
uniprot id: U4KN07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

61635:BN853 RS06085
gene id: 61635:BN853_RS06085
uniprot id: U4KT79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS04425
gene id: 61635:BN853_RS04425
uniprot id: U4KNM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

61635:BN853 RS01225
gene id: 61635:BN853_RS01225
uniprot id: U4KQY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

61635:BN853 RS04075
gene id: 61635:BN853_RS04075
uniprot id: U4KNH2
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS04000
gene id: 61635:BN853_RS04000
uniprot id: U4KNG1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

61635:BN853 RS00690
gene id: 61635:BN853_RS00690
uniprot id: U4KMB2
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS00700
gene id: 61635:BN853_RS00700
uniprot id: U4KQU7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

61635:BN853 RS05905
gene id: 61635:BN853_RS05905
uniprot id: U4KRZ1
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS03300
gene id: 61635:BN853_RS03300
uniprot id: U4KN10
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS01060
gene id: 61635:BN853_RS01060
uniprot id: U4KQY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

61635:BN853 RS02125
gene id: 61635:BN853_RS02125
uniprot id: U4KMS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS06895
gene id: 61635:BN853_RS06895
uniprot id: U4KPR9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

61635:BN853 RS05340
gene id: 61635:BN853_RS05340
uniprot id: U4KRU5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

61635:BN853 RS03260
gene id: 61635:BN853_RS03260
uniprot id: U4KSW7
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

61635:BN853 RS00930
gene id: 61635:BN853_RS00930
uniprot id: U4KM89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

61635:BN853 RS03135
gene id: 61635:BN853_RS03135
uniprot id: U4KSW2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

61635:BN853 RS00585
gene id: 61635:BN853_RS00585
uniprot id: U4KSL4
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS01690
gene id: 61635:BN853_RS01690
uniprot id: U4KSQ5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

61635:BN853 RS04155
gene id: 61635:BN853_RS04155
uniprot id: U4KNJ2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

61635:BN853 RS07000
gene id: 61635:BN853_RS07000
uniprot id: U4KPK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

61635:BN853 RS02255
gene id: 61635:BN853_RS02255
uniprot id: U4KMP4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

61635:BN853 RS06810
gene id: 61635:BN853_RS06810
uniprot id: U4KTA5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

61635:BN853 RS06935
gene id: 61635:BN853_RS06935
uniprot id: U4KTB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS05670
gene id: 61635:BN853_RS05670
uniprot id: U4KRX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

61635:BN853 RS06050
gene id: 61635:BN853_RS06050
uniprot id: U4KP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

61635:BN853 RS00940
gene id: 61635:BN853_RS00940
uniprot id: U4KSN0
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

61635:BN853 RS04665
gene id: 61635:BN853_RS04665
uniprot id: U4KRQ1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

61635:BN853 RS04135
gene id: 61635:BN853_RS04135
uniprot id: U4KNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

61635:BN853 RS01200
gene id: 61635:BN853_RS01200
uniprot id: U4KQY2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

61635:BN853 RS06915
gene id: 61635:BN853_RS06915
uniprot id: U4KPQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

61635:BN853 RS08335
gene id: 61635:BN853_RS08335
uniprot id: U4KSH1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

61635:BN853 RS01345
gene id: 61635:BN853_RS01345
uniprot id: U4KMF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

61635:BN853 RS06230
gene id: 61635:BN853_RS06230
uniprot id: U4KS18
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

61635:BN853 RS03005
gene id: 61635:BN853_RS03005
uniprot id: U4KRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

61635:BN853 RS01240
gene id: 61635:BN853_RS01240
uniprot id: U4KMG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

61635:BN853 RS01760
gene id: 61635:BN853_RS01760
uniprot id: U4KR23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

61635:BN853 RS05615
gene id: 61635:BN853_RS05615
uniprot id: U4KP80
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06900
gene id: 61635:BN853_RS06900
uniprot id: U4KPI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS09015
gene id: 61635:BN853_RS09015
uniprot id: U4KTF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

61635:BN853 RS06910
gene id: 61635:BN853_RS06910
uniprot id: U4KTA9
names: Similarity
messages: Belongs to the ArsC family.

61635:BN853 RS02625
gene id: 61635:BN853_RS02625
uniprot id: U4KSU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

61635:BN853 RS03075
gene id: 61635:BN853_RS03075
uniprot id: U4KMY3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

61635:BN853 RS04520
gene id: 61635:BN853_RS04520
uniprot id: U4KT17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

61635:BN853 RS02620
gene id: 61635:BN853_RS02620
uniprot id: U4KR87
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

61635:BN853 RS05985
gene id: 61635:BN853_RS05985
uniprot id: U4KT75
names: Similarity
messages: Belongs to the pyruvate kinase family.

61635:BN853 RS05115
gene id: 61635:BN853_RS05115
uniprot id: U4KRS9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

61635:BN853 RS07475
gene id: 61635:BN853_RS07475
uniprot id: U4KSB5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

61635:BN853 RS00875
gene id: 61635:BN853_RS00875
uniprot id: U4KMD8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

61635:BN853 RS04480
gene id: 61635:BN853_RS04480
uniprot id: U4KNP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

61635:BN853 RS00795
gene id: 61635:BN853_RS00795
uniprot id: U4KSM4
names: Similarity
messages: Belongs to the glutamine synthetase family.

61635:BN853 RS00950
gene id: 61635:BN853_RS00950
uniprot id: U4KME5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

61635:BN853 RS00970
gene id: 61635:BN853_RS00970
uniprot id: U4KMC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

61635:BN853 RS00910
gene id: 61635:BN853_RS00910
uniprot id: U4KQW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS01440
gene id: 61635:BN853_RS01440
uniprot id: U4KSP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61635:BN853 RS04550
gene id: 61635:BN853_RS04550
uniprot id: U4KNQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

61635:BN853 RS08380
gene id: 61635:BN853_RS08380
uniprot id: U4KQ50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

61635:BN853 RS03315
gene id: 61635:BN853_RS03315
uniprot id: U4KN50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

61635:BN853 RS02060
gene id: 61635:BN853_RS02060
uniprot id: U4KR52
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

61635:BN853 RS03630
gene id: 61635:BN853_RS03630
uniprot id: U4KRG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

61635:BN853 RS00815
gene id: 61635:BN853_RS00815
uniprot id: U4KQW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

61635:BN853 RS04850
gene id: 61635:BN853_RS04850
uniprot id: U4KNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

61635:BN853 RS01395
gene id: 61635:BN853_RS01395
uniprot id: U4KMG4
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS01535
gene id: 61635:BN853_RS01535
uniprot id: U4KR06
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

61635:BN853 RS06190
gene id: 61635:BN853_RS06190
uniprot id: U4KPF3
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06265
gene id: 61635:BN853_RS06265
uniprot id: U4KPG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61635:BN853 RS05110
gene id: 61635:BN853_RS05110
uniprot id: U4KNS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61635:BN853 RS08240
gene id: 61635:BN853_RS08240
uniprot id: U4KTG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS03635
gene id: 61635:BN853_RS03635
uniprot id: U4KSY2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

61635:BN853 RS01290
gene id: 61635:BN853_RS01290
uniprot id: U4KMF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

61635:BN853 RS06465
gene id: 61635:BN853_RS06465
uniprot id: U4KPL6
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS00155
gene id: 61635:BN853_RS00155
uniprot id: U4KLY2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

61635:BN853 RS01635
gene id: 61635:BN853_RS01635
uniprot id: U4KR14
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

61635:BN853 RS02410
gene id: 61635:BN853_RS02410
uniprot id: U4KR72
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

61635:BN853 RS03610
gene id: 61635:BN853_RS03610
uniprot id: U4KSY1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

61635:BN853 RS05965
gene id: 61635:BN853_RS05965
uniprot id: U4KPB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

61635:BN853 RS01235
gene id: 61635:BN853_RS01235
uniprot id: U4KME6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

61635:BN853 RS00540
gene id: 61635:BN853_RS00540
uniprot id: U4KM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

61635:BN853 RS07035
gene id: 61635:BN853_RS07035
uniprot id: U4KTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

61635:BN853 RS08370
gene id: 61635:BN853_RS08370
uniprot id: U4KQC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

61635:BN853 RS06635
gene id: 61635:BN853_RS06635
uniprot id: U4KS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

61635:BN853 RS08425
gene id: 61635:BN853_RS08425
uniprot id: U4KQE0
names: Similarity
messages: Belongs to the RpoE family.

61635:BN853 RS08710
gene id: 61635:BN853_RS08710
uniprot id: U4KTI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

61635:BN853 RS07450
gene id: 61635:BN853_RS07450
uniprot id: U4KSB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

61635:BN853 RS01005
gene id: 61635:BN853_RS01005
uniprot id: U4KMA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

61635:BN853 RS08440
gene id: 61635:BN853_RS08440
uniprot id: U4KTG9
names: Caution
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

61635:BN853 RS02135
gene id: 61635:BN853_RS02135
uniprot id: U4KR57
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS02040
gene id: 61635:BN853_RS02040
uniprot id: U4KSR9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

61635:BN853 RS06845
gene id: 61635:BN853_RS06845
uniprot id: U4KPQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

61635:BN853 RS01685
gene id: 61635:BN853_RS01685
uniprot id: U4KR18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

61635:BN853 RS04970
gene id: 61635:BN853_RS04970
uniprot id: U4KT35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

61635:BN853 RS07060
gene id: 61635:BN853_RS07060
uniprot id: U4KTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

61635:BN853 RS05665
gene id: 61635:BN853_RS05665
uniprot id: U4KNZ6
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06505
gene id: 61635:BN853_RS06505
uniprot id: U4KT96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS01565
gene id: 61635:BN853_RS01565
uniprot id: U4KSQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

61635:BN853 RS07100
gene id: 61635:BN853_RS07100
uniprot id: U4KPL8
names: Similarity
messages: Belongs to the peptidase S66 family.

61635:BN853 RS01645
gene id: 61635:BN853_RS01645
uniprot id: U4KMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.
messages: Cell membrane

61635:BN853 RS05630
gene id: 61635:BN853_RS05630
uniprot id: U4KP62
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

61635:BN853 RS04535
gene id: 61635:BN853_RS04535
uniprot id: U4KNJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

61635:BN853 RS02930
gene id: 61635:BN853_RS02930
uniprot id: U4KSV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS07675
gene id: 61635:BN853_RS07675
uniprot id: U4KTD9
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06325
gene id: 61635:BN853_RS06325
uniprot id: U4KPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

61635:BN853 RS01630
gene id: 61635:BN853_RS01630
uniprot id: U4KMG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

61635:BN853 RS06390
gene id: 61635:BN853_RS06390
uniprot id: U4KPK3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

61635:BN853 RS01495
gene id: 61635:BN853_RS01495
uniprot id: U4KMH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61635:BN853 RS00065
gene id: 61635:BN853_RS00065
uniprot id: U4KSI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

61635:BN853 RS01845
gene id: 61635:BN853_RS01845
uniprot id: U4KML5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

61635:BN853 RS02770
gene id: 61635:BN853_RS02770
uniprot id: U4KMV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

61635:BN853 RS06700
gene id: 61635:BN853_RS06700
uniprot id: U4KPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

61635:BN853 RS01555
gene id: 61635:BN853_RS01555
uniprot id: U4KMF7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

61635:BN853 RS00070
gene id: 61635:BN853_RS00070
uniprot id: U4KM14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

61635:BN853 RS06770
gene id: 61635:BN853_RS06770
uniprot id: U4KPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

61635:BN853 RS01790
gene id: 61635:BN853_RS01790
uniprot id: U4KSQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS00855
gene id: 61635:BN853_RS00855
uniprot id: U4KM79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

61635:BN853 RS08255
gene id: 61635:BN853_RS08255
uniprot id: U4KQ32
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

61635:BN853 RS06840
gene id: 61635:BN853_RS06840
uniprot id: U4KPP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

61635:BN853 RS03615
gene id: 61635:BN853_RS03615
uniprot id: U4KN98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

61635:BN853 RS01850
gene id: 61635:BN853_RS01850
uniprot id: U4KMN0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

61635:BN853 RS06310
gene id: 61635:BN853_RS06310
uniprot id: U4KT88
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

61635:BN853 RS05745
gene id: 61635:BN853_RS05745
uniprot id: U4KRX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

61635:BN853 RS05645
gene id: 61635:BN853_RS05645
uniprot id: U4KRX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

61635:BN853 RS01705
gene id: 61635:BN853_RS01705
uniprot id: U4KMH5
names: Similarity
messages: Belongs to the IMPACT family.

61635:BN853 RS00845
gene id: 61635:BN853_RS00845
uniprot id: U4KMB4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS06775
gene id: 61635:BN853_RS06775
uniprot id: U4KPG2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS07105
gene id: 61635:BN853_RS07105
uniprot id: U4KS85
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

61635:BN853 RS07610
gene id: 61635:BN853_RS07610
uniprot id: U4KQ19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

61635:BN853 RS02680
gene id: 61635:BN853_RS02680
uniprot id: U4KSU5
names: Similarity
messages: Belongs to the HsdR family.

61635:BN853 RS00905
gene id: 61635:BN853_RS00905
uniprot id: U4KM86
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

61635:BN853 RS06480
gene id: 61635:BN853_RS06480
uniprot id: U4KT95
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

61635:BN853 RS02890
gene id: 61635:BN853_RS02890
uniprot id: U4KN09
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS01310
gene id: 61635:BN853_RS01310
uniprot id: U4KSP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

61635:BN853 RS07830
gene id: 61635:BN853_RS07830
uniprot id: U4KQ49
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS01315
gene id: 61635:BN853_RS01315
uniprot id: U4KMF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

61635:BN853 RS01730
gene id: 61635:BN853_RS01730
uniprot id: U4KMH8
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS04965
gene id: 61635:BN853_RS04965
uniprot id: U4KRS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

61635:BN853 RS05155
gene id: 61635:BN853_RS05155
uniprot id: U4KP11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

61635:BN853 RS04220
gene id: 61635:BN853_RS04220
uniprot id: U4KT05
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

61635:BN853 RS05270
gene id: 61635:BN853_RS05270
uniprot id: U4KT47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

61635:BN853 RS01205
gene id: 61635:BN853_RS01205
uniprot id: U4KSN6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

61635:BN853 RS00370
gene id: 61635:BN853_RS00370
uniprot id: U4KSK5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

61635:BN853 RS01605
gene id: 61635:BN853_RS01605
uniprot id: U4KMG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

61635:BN853 RS03020
gene id: 61635:BN853_RS03020
uniprot id: U4KN25
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS04710
gene id: 61635:BN853_RS04710
uniprot id: U4KNM3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

61635:BN853 RS04760
gene id: 61635:BN853_RS04760
uniprot id: U4KNM9
names: Similarity
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

61635:BN853 RS07505
gene id: 61635:BN853_RS07505
uniprot id: U4KTD2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

61635:BN853 RS04640
gene id: 61635:BN853_RS04640
uniprot id: U4KRP9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

61635:BN853 RS01230
gene id: 61635:BN853_RS01230
uniprot id: U4KSN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

61635:BN853 RS01795
gene id: 61635:BN853_RS01795
uniprot id: U4KML2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

61635:BN853 RS04070
gene id: 61635:BN853_RS04070
uniprot id: U4KSZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS04735
gene id: 61635:BN853_RS04735
uniprot id: U4KNM6
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06360
gene id: 61635:BN853_RS06360
uniprot id: U4KT90
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

61635:BN853 RS02270
gene id: 61635:BN853_RS02270
uniprot id: U4KMS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS04370
gene id: 61635:BN853_RS04370
uniprot id: U4KT11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

61635:BN853 RS06025
gene id: 61635:BN853_RS06025
uniprot id: U4KP51
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS03245
gene id: 61635:BN853_RS03245
uniprot id: U4KN55
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

61635:BN853 RS04595
gene id: 61635:BN853_RS04595
uniprot id: U4KT20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

61635:BN853 RS01815
gene id: 61635:BN853_RS01815
uniprot id: U4KSR0
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

61635:BN853 RS01585
gene id: 61635:BN853_RS01585
uniprot id: U4KR09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

61635:BN853 RS00575
gene id: 61635:BN853_RS00575
uniprot id: U4KM39
names: Similarity
messages: Belongs to the FemABX family.

61635:BN853 RS01390
gene id: 61635:BN853_RS01390
uniprot id: U4KSP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

61635:BN853 RS04955
gene id: 61635:BN853_RS04955
uniprot id: U4KNX9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

61635:BN853 RS01035
gene id: 61635:BN853_RS01035
uniprot id: U4KQX7
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS01940
gene id: 61635:BN853_RS01940
uniprot id: U4KSR5
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

61635:BN853 RS02285
gene id: 61635:BN853_RS02285
uniprot id: U4KR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS06955
gene id: 61635:BN853_RS06955
uniprot id: U4KS73
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

61635:BN853 RS03355
gene id: 61635:BN853_RS03355
uniprot id: U4KRE5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

61635:BN853 RS01325
gene id: 61635:BN853_RS01325
uniprot id: U4KMC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

61635:BN853 RS06315
gene id: 61635:BN853_RS06315
uniprot id: U4KPH3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

61635:BN853 RS03225
gene id: 61635:BN853_RS03225
uniprot id: U4KN01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61635:BN853 RS04150
gene id: 61635:BN853_RS04150
uniprot id: U4KNI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS06195
gene id: 61635:BN853_RS06195
uniprot id: U4KPH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS05330
gene id: 61635:BN853_RS05330
uniprot id: U4KP37
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

61635:BN853 RS01570
gene id: 61635:BN853_RS01570
uniprot id: U4KMI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

61635:BN853 RS01330
gene id: 61635:BN853_RS01330
uniprot id: U4KQZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

61635:BN853 RS01350
gene id: 61635:BN853_RS01350
uniprot id: U4KMH7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

61635:BN853 RS02120
gene id: 61635:BN853_RS02120
uniprot id: U4KMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS04300
gene id: 61635:BN853_RS04300
uniprot id: U4KNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS04875
gene id: 61635:BN853_RS04875
uniprot id: U4KNU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

61635:BN853 RS04145
gene id: 61635:BN853_RS04145
uniprot id: U4KT02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS03095
gene id: 61635:BN853_RS03095
uniprot id: U4KN33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

61635:BN853 RS08665
gene id: 61635:BN853_RS08665
uniprot id: U4KQG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS07260
gene id: 61635:BN853_RS07260
uniprot id: U4KTC3
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

61635:BN853 RS02295
gene id: 61635:BN853_RS02295
uniprot id: U4KMS3
names: Similarity
messages: Belongs to the peptidase M29 family.

61635:BN853 RS03880
gene id: 61635:BN853_RS03880
uniprot id: U4KNF3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

61635:BN853 RS06340
gene id: 61635:BN853_RS06340
uniprot id: U4KPH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS02965
gene id: 61635:BN853_RS02965
uniprot id: U4KN18
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

61635:BN853 RS01015
gene id: 61635:BN853_RS01015
uniprot id: U4KSN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

61635:BN853 RS04630
gene id: 61635:BN853_RS04630
uniprot id: U4KNT5
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS05440
gene id: 61635:BN853_RS05440
uniprot id: U4KRV4
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS05940
gene id: 61635:BN853_RS05940
uniprot id: U4KPB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

61635:BN853 RS07030
gene id: 61635:BN853_RS07030
uniprot id: U4KS79
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

61635:BN853 RS06805
gene id: 61635:BN853_RS06805
uniprot id: U4KS61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

61635:BN853 RS08290
gene id: 61635:BN853_RS08290
uniprot id: U4KTG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS03170
gene id: 61635:BN853_RS03170
uniprot id: U4KN44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

61635:BN853 RS03810
gene id: 61635:BN853_RS03810
uniprot id: U4KN79
names: Similarity
messages: Belongs to the peptidase C1 family.

61635:BN853 RS01070
gene id: 61635:BN853_RS01070
uniprot id: U4KME0
names: Similarity
messages: Belongs to the ParB family.

61635:BN853 RS01285
gene id: 61635:BN853_RS01285
uniprot id: U4KSN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

61635:BN853 RS05880
gene id: 61635:BN853_RS05880
uniprot id: U4KRY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

61635:BN853 RS03580
gene id: 61635:BN853_RS03580
uniprot id: U4KRG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

61635:BN853 RS06800
gene id: 61635:BN853_RS06800
uniprot id: U4KPG6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS08325
gene id: 61635:BN853_RS08325
uniprot id: U4KQC8
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS06220
gene id: 61635:BN853_RS06220
uniprot id: U4KPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

61635:BN853 RS05345
gene id: 61635:BN853_RS05345
uniprot id: U4KT50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

61635:BN853 RS08365
gene id: 61635:BN853_RS08365
uniprot id: U4KTG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

61635:BN853 RS06885
gene id: 61635:BN853_RS06885
uniprot id: U4KTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

61635:BN853 RS07010
gene id: 61635:BN853_RS07010
uniprot id: U4KTB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

61635:BN853 RS04090
gene id: 61635:BN853_RS04090
uniprot id: U4KRK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS03015
gene id: 61635:BN853_RS03015
uniprot id: U4KN11
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

61635:BN853 RS02045
gene id: 61635:BN853_RS02045
uniprot id: U4KMP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS04260
gene id: 61635:BN853_RS04260
uniprot id: U4KNE6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

61635:BN853 RS08540
gene id: 61635:BN853_RS08540
uniprot id: U4KTH3
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

61635:BN853 RS03175
gene id: 61635:BN853_RS03175
uniprot id: U4KMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

61635:BN853 RS01875
gene id: 61635:BN853_RS01875
uniprot id: U4KMN2
names: Similarity
messages: Belongs to the fabD family.

61635:BN853 RS01510
gene id: 61635:BN853_RS01510
uniprot id: U4KR04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

61635:BN853 RS00455
gene id: 61635:BN853_RS00455
uniprot id: U4KM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS03585
gene id: 61635:BN853_RS03585
uniprot id: U4KSY0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

61635:BN853 RS05485
gene id: 61635:BN853_RS05485
uniprot id: U4KNX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

61635:BN853 RS06615
gene id: 61635:BN853_RS06615
uniprot id: U4KTA0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

61635:BN853 RS01430
gene id: 61635:BN853_RS01430
uniprot id: U4KMD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

61635:BN853 RS03895
gene id: 61635:BN853_RS03895
uniprot id: U4KSZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS06175
gene id: 61635:BN853_RS06175
uniprot id: U4KP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS00145
gene id: 61635:BN853_RS00145
uniprot id: U4KM22
names: Similarity
messages: Belongs to the polysaccharide synthase family.

61635:BN853 RS02640
gene id: 61635:BN853_RS02640
uniprot id: U4KMT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

61635:BN853 RS02315
gene id: 61635:BN853_RS02315
uniprot id: U4KST0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS06150
gene id: 61635:BN853_RS06150
uniprot id: U4KP73
names: Similarity
messages: Belongs to the DEAD box helicase family.

61635:BN853 RS00225
gene id: 61635:BN853_RS00225
uniprot id: U4KM56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

61635:BN853 RS02860
gene id: 61635:BN853_RS02860
uniprot id: U4KN06
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

61635:BN853 RS04130
gene id: 61635:BN853_RS04130
uniprot id: U4KNJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS00160
gene id: 61635:BN853_RS00160
uniprot id: U4KQR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS01615
gene id: 61635:BN853_RS01615
uniprot id: U4KSQ2
names: Similarity
messages: Belongs to the peptidase S1C family.

61635:BN853 RS02000
gene id: 61635:BN853_RS02000
uniprot id: U4KMQ2
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS08635
gene id: 61635:BN853_RS08635
uniprot id: U4KSJ6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

61635:BN853 RS08185
gene id: 61635:BN853_RS08185
uniprot id: U4KQ20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

61635:BN853 RS08715
gene id: 61635:BN853_RS08715
uniprot id: U4KQH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

61635:BN853 RS05685
gene id: 61635:BN853_RS05685
uniprot id: U4KP90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

61635:BN853 RS02615
gene id: 61635:BN853_RS02615
uniprot id: U4KMT0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

61635:BN853 RS05850
gene id: 61635:BN853_RS05850
uniprot id: U4KRY7
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS08200
gene id: 61635:BN853_RS08200
uniprot id: U4KQA2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

61635:BN853 RS01220
gene id: 61635:BN853_RS01220
uniprot id: U4KMB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

61635:BN853 RS04615
gene id: 61635:BN853_RS04615
uniprot id: U4KRP8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

61635:BN853 RS00020
gene id: 61635:BN853_RS00020
uniprot id: U4KM08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

61635:BN853 RS04390
gene id: 61635:BN853_RS04390
uniprot id: U4KRM9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

61635:BN853 RS06200
gene id: 61635:BN853_RS06200
uniprot id: U4KP81
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS02995
gene id: 61635:BN853_RS02995
uniprot id: U4KN22
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS04565
gene id: 61635:BN853_RS04565
uniprot id: U4KRP5
names: Similarity
messages: Belongs to the ribF family.

61635:BN853 RS01210
gene id: 61635:BN853_RS01210
uniprot id: U4KME3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

61635:BN853 RS01515
gene id: 61635:BN853_RS01515
uniprot id: U4KSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

61635:BN853 RS00345
gene id: 61635:BN853_RS00345
uniprot id: U4KQS5
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

61635:BN853 RS08450
gene id: 61635:BN853_RS08450
uniprot id: U4KQE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

61635:BN853 RS02785
gene id: 61635:BN853_RS02785
uniprot id: U4KMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

61635:BN853 RS00550
gene id: 61635:BN853_RS00550
uniprot id: U4KM36
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

61635:BN853 RS05365
gene id: 61635:BN853_RS05365
uniprot id: U4KRU7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

61635:BN853 RS01990
gene id: 61635:BN853_RS01990
uniprot id: U4KSR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS07430
gene id: 61635:BN853_RS07430
uniprot id: U4KTC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS07055
gene id: 61635:BN853_RS07055
uniprot id: U4KS81
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

61635:BN853 RS07465
gene id: 61635:BN853_RS07465
uniprot id: U4KQ25
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

61635:BN853 RS08485
gene id: 61635:BN853_RS08485
uniprot id: U4KSI4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

61635:BN853 RS03265
gene id: 61635:BN853_RS03265
uniprot id: U4KN42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

61635:BN853 RS07800
gene id: 61635:BN853_RS07800
uniprot id: U4KTE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

61635:BN853 RS03185
gene id: 61635:BN853_RS03185
uniprot id: U4KSW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61635:BN853 RS01050
gene id: 61635:BN853_RS01050
uniprot id: U4KMF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

61635:BN853 RS06470
gene id: 61635:BN853_RS06470
uniprot id: U4KPC5
names: Similarity
messages: Belongs to the pyruvate kinase family.

61635:BN853 RS00110
gene id: 61635:BN853_RS00110
uniprot id: U4KQR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

61635:BN853 RS03945
gene id: 61635:BN853_RS03945
uniprot id: U4KSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

61635:BN853 RS01010
gene id: 61635:BN853_RS01010
uniprot id: U4KQX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS06260
gene id: 61635:BN853_RS06260
uniprot id: U4KT86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

61635:BN853 RS03980
gene id: 61635:BN853_RS03980
uniprot id: U4KNH0
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

61635:BN853 RS08390
gene id: 61635:BN853_RS08390
uniprot id: U4KTG7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS01470
gene id: 61635:BN853_RS01470
uniprot id: U4KMH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS08150
gene id: 61635:BN853_RS08150
uniprot id: U4KQ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

61635:BN853 RS05635
gene id: 61635:BN853_RS05635
uniprot id: U4KP84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

61635:BN853 RS04580
gene id: 61635:BN853_RS04580
uniprot id: U4KNS7
names: Similarity
messages: Belongs to the thioredoxin family.

61635:BN853 RS00435
gene id: 61635:BN853_RS00435
uniprot id: U4KQS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

61635:BN853 RS04895
gene id: 61635:BN853_RS04895
uniprot id: U4KT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

61635:BN853 RS00055
gene id: 61635:BN853_RS00055
uniprot id: U4KLW8
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

61635:BN853 RS05695
gene id: 61635:BN853_RS05695
uniprot id: U4KRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

61635:BN853 RS04385
gene id: 61635:BN853_RS04385
uniprot id: U4KNG4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS03080
gene id: 61635:BN853_RS03080
uniprot id: U4KRC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS04840
gene id: 61635:BN853_RS04840
uniprot id: U4KRR3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

61635:BN853 RS03255
gene id: 61635:BN853_RS03255
uniprot id: U4KRD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

61635:BN853 RS07310
gene id: 61635:BN853_RS07310
uniprot id: U4KPX6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

61635:BN853 RS01355
gene id: 61635:BN853_RS01355
uniprot id: U4KMC9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

61635:BN853 RS05660
gene id: 61635:BN853_RS05660
uniprot id: U4KP87
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS05005
gene id: 61635:BN853_RS05005
uniprot id: U4KNY7
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS05120
gene id: 61635:BN853_RS05120
uniprot id: U4KT41
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

61635:BN853 RS05680
gene id: 61635:BN853_RS05680
uniprot id: U4KP70
names: Similarity
messages: Belongs to the TlyA family.

61635:BN853 RS02610
gene id: 61635:BN853_RS02610
uniprot id: U4KMX9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

61635:BN853 RS06080
gene id: 61635:BN853_RS06080
uniprot id: U4KS06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS03775
gene id: 61635:BN853_RS03775
uniprot id: U4KNC3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

61635:BN853 RS01735
gene id: 61635:BN853_RS01735
uniprot id: U4KR21
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

61635:BN853 RS05960
gene id: 61635:BN853_RS05960
uniprot id: U4KT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

61635:BN853 RS02070
gene id: 61635:BN853_RS02070
uniprot id: U4KMQ0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

61635:BN853 RS06510
gene id: 61635:BN853_RS06510
uniprot id: U4KPK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS03905
gene id: 61635:BN853_RS03905
uniprot id: U4KNF6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

61635:BN853 RS01900
gene id: 61635:BN853_RS01900
uniprot id: U4KMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

61635:BN853 RS07335
gene id: 61635:BN853_RS07335
uniprot id: U4KPX9
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS04230
gene id: 61635:BN853_RS04230
uniprot id: U4KNK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

61635:BN853 RS01655
gene id: 61635:BN853_RS01655
uniprot id: U4KMG9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

61635:BN853 RS02955
gene id: 61635:BN853_RS02955
uniprot id: U4KSV5
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

61635:BN853 RS04900
gene id: 61635:BN853_RS04900
uniprot id: U4KNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS04570
gene id: 61635:BN853_RS04570
uniprot id: U4KT19
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

61635:BN853 RS02400
gene id: 61635:BN853_RS02400
uniprot id: U4KMV4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

61635:BN853 RS04625
gene id: 61635:BN853_RS04625
uniprot id: U4KNR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

61635:BN853 RS04485
gene id: 61635:BN853_RS04485
uniprot id: U4KNH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

61635:BN853 RS00595
gene id: 61635:BN853_RS00595
uniprot id: U4KMA1
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS03835
gene id: 61635:BN853_RS03835
uniprot id: U4KN84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

61635:BN853 RS04175
gene id: 61635:BN853_RS04175
uniprot id: U4KNI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

61635:BN853 RS06245
gene id: 61635:BN853_RS06245
uniprot id: U4KPI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

61635:BN853 RS01295
gene id: 61635:BN853_RS01295
uniprot id: U4KMH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

61635:BN853 RS06475
gene id: 61635:BN853_RS06475
uniprot id: U4KS40
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

61635:BN853 RS03100
gene id: 61635:BN853_RS03100
uniprot id: U4KMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

61635:BN853 RS05655
gene id: 61635:BN853_RS05655
uniprot id: U4KP66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

61635:BN853 RS06180
gene id: 61635:BN853_RS06180
uniprot id: U4KS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

61635:BN853 RS00140
gene id: 61635:BN853_RS00140
uniprot id: U4KSI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

61635:BN853 RS08630
gene id: 61635:BN853_RS08630
uniprot id: U4KQ88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

61635:BN853 RS04275
gene id: 61635:BN853_RS04275
uniprot id: U4KNK1
names: Similarity
messages: Belongs to the UxaA family.

61635:BN853 RS04730
gene id: 61635:BN853_RS04730
uniprot id: U4KNV0
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS04245
gene id: 61635:BN853_RS04245
uniprot id: U4KT06
names: Subcellular Location Annotation
messages: Cytoplasm

61635:BN853 RS07350
gene id: 61635:BN853_RS07350
uniprot id: U4KSA7
names: Similarity
messages: Belongs to the Dps family.

61635:BN853 RS05570
gene id: 61635:BN853_RS05570
uniprot id: U4KRW4
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS04870
gene id: 61635:BN853_RS04870
uniprot id: U4KT31
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

61635:BN853 RS06870
gene id: 61635:BN853_RS06870
uniprot id: U4KPR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS07425
gene id: 61635:BN853_RS07425
uniprot id: U4KSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS01215
gene id: 61635:BN853_RS01215
uniprot id: U4KMG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

61635:BN853 RS01560
gene id: 61635:BN853_RS01560
uniprot id: U4KR08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

61635:BN853 RS01660
gene id: 61635:BN853_RS01660
uniprot id: U4KR15
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

61635:BN853 RS05080
gene id: 61635:BN853_RS05080
uniprot id: U4KNZ5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

61635:BN853 RS05075
gene id: 61635:BN853_RS05075
uniprot id: U4KNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

61635:BN853 RS01270
gene id: 61635:BN853_RS01270
uniprot id: U4KMB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

61635:BN853 RS08755
gene id: 61635:BN853_RS08755
uniprot id: U4KNR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

61635:BN853 RS08680
gene id: 61635:BN853_RS08680
uniprot id: U4KSK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS04185
gene id: 61635:BN853_RS04185
uniprot id: U4KND6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

61635:BN853 RS02775
gene id: 61635:BN853_RS02775
uniprot id: U4KR99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

61635:BN853 RS06440
gene id: 61635:BN853_RS06440
uniprot id: U4KPL2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

61635:BN853 RS03930
gene id: 61635:BN853_RS03930
uniprot id: U4KNG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

61635:BN853 RS05105
gene id: 61635:BN853_RS05105
uniprot id: U4KNZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

61635:BN853 RS06135
gene id: 61635:BN853_RS06135
uniprot id: U4KT81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

61635:BN853 RS00465
gene id: 61635:BN853_RS00465
uniprot id: U4KSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS04335
gene id: 61635:BN853_RS04335
uniprot id: U4KNF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

61635:BN853 RS03925
gene id: 61635:BN853_RS03925
uniprot id: U4KNE8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

61635:BN853 RS02515
gene id: 61635:BN853_RS02515
uniprot id: U4KMV2
names: Similarity
messages: Belongs to the peptidase S66 family.

61635:BN853 RS03830
gene id: 61635:BN853_RS03830
uniprot id: U4KNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

61635:BN853 RS01320
gene id: 61635:BN853_RS01320
uniprot id: U4KMH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

61635:BN853 RS05690
gene id: 61635:BN853_RS05690
uniprot id: U4KNZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

61635:BN853 RS07780
gene id: 61635:BN853_RS07780
uniprot id: U4KQ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

61635:BN853 RS01885
gene id: 61635:BN853_RS01885
uniprot id: U4KR34
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

61635:BN853 RS00080
gene id: 61635:BN853_RS00080
uniprot id: U4KLX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

61635:BN853 RS04465
gene id: 61635:BN853_RS04465
uniprot id: U4KRN5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

61635:BN853 RS05165
gene id: 61635:BN853_RS05165
uniprot id: U4KRT1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

61635:BN853 RS03650
gene id: 61635:BN853_RS03650
uniprot id: U4KN57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS06950
gene id: 61635:BN853_RS06950
uniprot id: U4KPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

61635:BN853 RS04990
gene id: 61635:BN853_RS04990
uniprot id: U4KRS3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

61635:BN853 RS07050
gene id: 61635:BN853_RS07050
uniprot id: U4KPL0
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

61635:BN853 RS07570
gene id: 61635:BN853_RS07570
uniprot id: U4KPU2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

61635:BN853 RS04490
gene id: 61635:BN853_RS04490
uniprot id: U4KRN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

61635:BN853 RS05710
gene id: 61635:BN853_RS05710
uniprot id: U4KP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS05895
gene id: 61635:BN853_RS05895
uniprot id: U4KPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

61635:BN853 RS06855
gene id: 61635:BN853_RS06855
uniprot id: U4KS65
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

61635:BN853 RS08460
gene id: 61635:BN853_RS08460
uniprot id: U4KSI2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

61635:BN853 RS08175
gene id: 61635:BN853_RS08175
uniprot id: U4KQ98
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

61635:BN853 RS06765
gene id: 61635:BN853_RS06765
uniprot id: U4KPN4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

61635:BN853 RS02495
gene id: 61635:BN853_RS02495
uniprot id: U4KMW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

61635:BN853 RS04530
gene id: 61635:BN853_RS04530
uniprot id: U4KNQ7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

61635:BN853 RS03860
gene id: 61635:BN853_RS03860
uniprot id: U4KN86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

61635:BN853 RS02010
gene id: 61635:BN853_RS02010
uniprot id: U4KR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS03120
gene id: 61635:BN853_RS03120
uniprot id: U4KN36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

61635:BN853 RS00580
gene id: 61635:BN853_RS00580
uniprot id: U4KQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

61635:BN853 RS03200
gene id: 61635:BN853_RS03200
uniprot id: U4KMZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

61635:BN853 RS01880
gene id: 61635:BN853_RS01880
uniprot id: U4KMJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

61635:BN853 RS02350
gene id: 61635:BN853_RS02350
uniprot id: U4KMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

61635:BN853 RS08205
gene id: 61635:BN853_RS08205
uniprot id: U4KQB5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

61635:BN853 RS00420
gene id: 61635:BN853_RS00420
uniprot id: U4KM58
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

61635:BN853 RS00190
gene id: 61635:BN853_RS00190
uniprot id: U4KSJ1
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

61635:BN853 RS04120
gene id: 61635:BN853_RS04120
uniprot id: U4KT01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

61635:BN853 RS04865
gene id: 61635:BN853_RS04865
uniprot id: U4KRR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

61635:BN853 RS08210
gene id: 61635:BN853_RS08210
uniprot id: U4KQ24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

61635:BN853 RS07125
gene id: 61635:BN853_RS07125
uniprot id: U4KPN2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

61635:BN853 RS05350
gene id: 61635:BN853_RS05350
uniprot id: U4KP16
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

61635:BN853 RS01860
gene id: 61635:BN853_RS01860
uniprot id: U4KR31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

61635:BN853 RS01405
gene id: 61635:BN853_RS01405
uniprot id: U4KMD6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

61635:BN853 RS00130
gene id: 61635:BN853_RS00130
uniprot id: U4KLX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

61635:BN853 RS05250
gene id: 61635:BN853_RS05250
uniprot id: U4KP00
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

61635:BN853 RS04235
gene id: 61635:BN853_RS04235
uniprot id: U4KNE2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

61635:BN853 RS02960
gene id: 61635:BN853_RS02960
uniprot id: U4KN05
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

61635:BN853 RS06225
gene id: 61635:BN853_RS06225
uniprot id: U4KP85
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

61635:BN853 RS05145
gene id: 61635:BN853_RS05145
uniprot id: U4KT42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

61635:BN853 RS05675
gene id: 61635:BN853_RS05675
uniprot id: U4KT63
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

61635:BN853 RS00790
gene id: 61635:BN853_RS00790
uniprot id: U4KQV7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

61635:BN853 RS01595
gene id: 61635:BN853_RS01595
uniprot id: U4KMI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

61635:BN853 RS03595
gene id: 61635:BN853_RS03595
uniprot id: U4KNB0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

61635:BN853 RS03575
gene id: 61635:BN853_RS03575
uniprot id: U4KN45
names: Subcellular Location Annotation
messages: Membrane

61635:BN853 RS02095
gene id: 61635:BN853_RS02095
uniprot id: U4KMQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

61635:BN853 RS05275
gene id: 61635:BN853_RS05275
uniprot id: U4KP04
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

61635:BN853 RS08035
gene id: 61635:BN853_RS08035
uniprot id: U4KSE7
names: Similarity
messages: Belongs to the peptidase M13 family.