59894:MID1
gene id: 59894:MID1
uniprot id: U3JPI3
names: Subcellular Location Annotation
messages: cytoskeleton

59894:PDE6B
gene id: 59894:PDE6B
uniprot id: A0A803V9A0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:ZW10
gene id: 59894:ZW10
uniprot id: U3JTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

59894:TMEM200A
gene id: 59894:TMEM200A
uniprot id: U3KLM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

59894:NLGN1
gene id: 59894:NLGN1
uniprot id: A0A803W6E1
uniprot id: U3K190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

59894:UBL3
gene id: 59894:UBL3
uniprot id: U3K1H4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:GGNBP2
gene id: 59894:GGNBP2
uniprot id: U3JS00
uniprot id: U3JS03
names: Function
messages: May be involved in spermatogenesis.

59894:LOC101821588
gene id: 59894:LOC101821588
uniprot id: U3JZE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

59894:BDNF
gene id: 59894:BDNF
uniprot id: A0A803V5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

59894:NTS
gene id: 59894:NTS
uniprot id: A0A803V1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

59894:GLIS3
gene id: 59894:GLIS3
uniprot id: U3K7G9
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

59894:UBR1
gene id: 59894:UBR1
uniprot id: A0A803V0U1
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

59894:GOLM1
gene id: 59894:GOLM1
uniprot id: A0A803V808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

59894:STXBP5L
gene id: 59894:STXBP5L
uniprot id: A0A803VBT1
uniprot id: A0A803VKW4
uniprot id: A0A803WED3
uniprot id: U3JRU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

59894:SCAMP5
gene id: 59894:SCAMP5
uniprot id: A0A803W0P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

59894:OPRL1
gene id: 59894:OPRL1
uniprot id: U3K6Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

59894:TET2
gene id: 59894:TET2
uniprot id: U3K0N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

59894:YWHAE
gene id: 59894:YWHAE
uniprot id: A0A803VGV7
uniprot id: A0A803VJK4
names: Similarity
messages: Belongs to the 14-3-3 family.

59894:MYOZ1
gene id: 59894:MYOZ1
uniprot id: U3JX94
names: Similarity
messages: Belongs to the myozenin family.

59894:MAP1LC3C
gene id: 59894:MAP1LC3C
uniprot id: U3KFA5
names: Similarity
messages: Belongs to the ATG8 family.

59894:ABCB9
gene id: 59894:ABCB9
uniprot id: U3K3N4
names: Subcellular Location Annotation
messages: Membrane

59894:KIF14
gene id: 59894:KIF14
uniprot id: U3JJ76
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:SLC7A4
gene id: 59894:SLC7A4
uniprot id: U3JWK9
names: Subcellular Location Annotation
messages: Membrane

59894:PLPP3
gene id: 59894:PLPP3
uniprot id: U3KCN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

59894:PANK4
gene id: 59894:PANK4
uniprot id: U3K4K4
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

59894:NR2C1
gene id: 59894:NR2C1
uniprot id: A0A803VG68
uniprot id: A0A803W6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:CYGB
gene id: 59894:CYGB
uniprot id: U3JDW8
names: Similarity
messages: Belongs to the globin family.

59894:GSG1L
gene id: 59894:GSG1L
uniprot id: U3JN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

59894:SLC15A4
gene id: 59894:SLC15A4
uniprot id: U3K4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

59894:GGA1
gene id: 59894:GGA1
uniprot id: A0A803WF14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

59894:TMEM129
gene id: 59894:TMEM129
uniprot id: U3K5W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

59894:AP2B1
gene id: 59894:AP2B1
uniprot id: A0A803VP36
uniprot id: A0A803WE09
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

59894:TP53INP1
gene id: 59894:TP53INP1
uniprot id: A0A803W9E8
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

59894:PICALM
gene id: 59894:PICALM
uniprot id: A0A803VR32
uniprot id: A0A803W5G6
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

59894:CD247
gene id: 59894:CD247
uniprot id: A0A803W4N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

59894:LOC107603318
gene id: 59894:LOC107603318
uniprot id: A0A803V4Z5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:KIF11
gene id: 59894:KIF11
uniprot id: A0A803VX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

59894:GOLT1B
gene id: 59894:GOLT1B
uniprot id: U3JIZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

59894:GLB1
gene id: 59894:GLB1
uniprot id: U3KD22
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

59894:B3GNT7
gene id: 59894:B3GNT7
uniprot id: U3KLK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:LPAR6
gene id: 59894:LPAR6
uniprot id: A0A803VY78
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:MFF
gene id: 59894:MFF
uniprot id: A0A803VD50
uniprot id: A0A803W4U0
uniprot id: A0A803WEX9
uniprot id: U3JWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

59894:ALDH1A2
gene id: 59894:ALDH1A2
uniprot id: U3KCL4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

59894:SCUBE1
gene id: 59894:SCUBE1
uniprot id: U3JVY5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:PRKCD
gene id: 59894:PRKCD
uniprot id: U3JLH3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.
messages: Cytoplasm
messages: Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: perinuclear region

59894:EIF3D
gene id: 59894:EIF3D
uniprot id: U3KEX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

59894:DYNLL2
gene id: 59894:DYNLL2
uniprot id: U3JYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

59894:PITX3
gene id: 59894:PITX3
uniprot id: A0A803VKN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

59894:REEP1
gene id: 59894:REEP1
uniprot id: A0A803VND9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

59894:MIS12
gene id: 59894:MIS12
uniprot id: U3KL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

59894:SEMA4D
gene id: 59894:SEMA4D
uniprot id: A0A803V672
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:UVSSA
gene id: 59894:UVSSA
uniprot id: U3K605
names: Similarity
messages: Belongs to the UVSSA family.

59894:FAM149A
gene id: 59894:FAM149A
uniprot id: U3KBS5
names: Similarity
messages: Belongs to the FAM149 family.

59894:CASP7
gene id: 59894:CASP7
uniprot id: A0A803VAZ6
names: Similarity
messages: Belongs to the peptidase C14A family.

59894:TMEM200C
gene id: 59894:TMEM200C
uniprot id: U3KIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

59894:ADPRHL2
gene id: 59894:ADPRHL2
uniprot id: A0A803WGU8
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

59894:LOC101814981
gene id: 59894:LOC101814981
uniprot id: A0A803VIG4
uniprot id: U3JY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

59894:TSPO2
gene id: 59894:TSPO2
uniprot id: U3JMR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

59894:TYRO3
gene id: 59894:TYRO3
uniprot id: U3JU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

59894:MCCC2
gene id: 59894:MCCC2
uniprot id: U3KCS1
names: Similarity
messages: Belongs to the AccD/PCCB family.

59894:SLC2A5
gene id: 59894:SLC2A5
uniprot id: U3JY23
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:PSMA3
gene id: 59894:PSMA3
uniprot id: U3JLS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

59894:AQP9
gene id: 59894:AQP9
uniprot id: A0A803W925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

59894:PIPOX
gene id: 59894:PIPOX
uniprot id: A0A803V9J0
names: Similarity
messages: Belongs to the MSOX/MTOX family.

59894:CENPM
gene id: 59894:CENPM
uniprot id: U3KB97
names: Subcellular Location Annotation
messages: Nucleus

59894:TIMM10
gene id: 59894:TIMM10
uniprot id: U3K9H0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

59894:LOC101814338
gene id: 59894:LOC101814338
uniprot id: U3K4H5
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

59894:FAN1
gene id: 59894:FAN1
uniprot id: U3KDG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

59894:GFOD1
gene id: 59894:GFOD1
uniprot id: U3KG07
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

59894:PAMR1
gene id: 59894:PAMR1
uniprot id: U3KD97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:NR0B2
gene id: 59894:NR0B2
uniprot id: U3JVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

59894:LDB1
gene id: 59894:LDB1
uniprot id: U3K1G7
names: Similarity
messages: Belongs to the LDB family.

59894:ORMDL3
gene id: 59894:ORMDL3
uniprot id: A0A803VES7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

59894:FIGN
gene id: 59894:FIGN
uniprot id: U3KKF0
names: Similarity
messages: Belongs to the AAA ATPase family.

59894:RPN1
gene id: 59894:RPN1
uniprot id: U3JZR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

59894:HNF4A
gene id: 59894:HNF4A
uniprot id: A0A803W2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:RBFOX2
gene id: 59894:RBFOX2
uniprot id: A0A803W5D1
uniprot id: A0A803W7N4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

59894:SENP2
gene id: 59894:SENP2
uniprot id: U3KFV4
names: Similarity
messages: Belongs to the peptidase C48 family.

59894:LOC107604235
gene id: 59894:LOC107604235
uniprot id: A0A803VNM5
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:CPEB3
gene id: 59894:CPEB3
uniprot id: A0A803VAL9
uniprot id: A0A803W7X8
names: Similarity
messages: Belongs to the RRM CPEB family.

59894:NTNG2
gene id: 59894:NTNG2
uniprot id: U3JFH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:SPIN1
gene id: 59894:SPIN1
uniprot id: U3KD53
names: Similarity
messages: Belongs to the SPIN/STSY family.

59894:TDRD7
gene id: 59894:TDRD7
uniprot id: U3JEL9
names: Subcellular Location Annotation
messages: Cytoplasm

59894:SERPINA10
gene id: 59894:SERPINA10
uniprot id: U3JIJ6
names: Similarity
messages: Belongs to the serpin family.

59894:FBLN5
gene id: 59894:FBLN5
uniprot id: A0A803W0V0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101810982
gene id: 59894:LOC101810982
uniprot id: A0A803VMU9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

59894:SSRP1
gene id: 59894:SSRP1
uniprot id: U3K9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

59894:SOX11
gene id: 59894:SOX11
uniprot id: U3KJG5
names: Subcellular Location Annotation
messages: Nucleus

59894:INPP4A
gene id: 59894:INPP4A
uniprot id: A0A803V5L2
uniprot id: U3JMZ0
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

59894:SS18L1
gene id: 59894:SS18L1
uniprot id: U3K7Q4
names: Similarity
messages: Belongs to the SS18 family.

59894:TAF4
gene id: 59894:TAF4
uniprot id: U3K7T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

59894:RAPGEF2
gene id: 59894:RAPGEF2
uniprot id: A0A803V831
uniprot id: A0A803VCM2
uniprot id: A0A803VPY7
names: Similarity
messages: Belongs to the RAPGEF2 family.

59894:ABCC3
gene id: 59894:ABCC3
uniprot id: U3JF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

59894:LOC101805755
gene id: 59894:LOC101805755
uniprot id: A0A803WDF1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

59894:LOC101815454
gene id: 59894:LOC101815454
uniprot id: A0A803VMG4
uniprot id: A0A803W854
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

59894:LOC101808700
gene id: 59894:LOC101808700
uniprot id: U3JS51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

59894:ERG
gene id: 59894:ERG
uniprot id: A0A803V891
uniprot id: A0A803VJR2
uniprot id: U3JRA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:MAL2
gene id: 59894:MAL2
uniprot id: A0A803WCL7
names: Subcellular Location Annotation
messages: Membrane

59894:TNFAIP2
gene id: 59894:TNFAIP2
uniprot id: U3JJG5
names: Similarity
messages: Belongs to the SEC6 family.

59894:MFN1
gene id: 59894:MFN1
uniprot id: U3K134
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

59894:CHRNG
gene id: 59894:CHRNG
uniprot id: U3JZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:NAALADL2
gene id: 59894:NAALADL2
uniprot id: U3K178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Membrane

59894:PAPSS1
gene id: 59894:PAPSS1
uniprot id: A0A803V140
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

59894:ACYP1
gene id: 59894:ACYP1
uniprot id: U3JV14
names: Similarity
messages: Belongs to the acylphosphatase family.

59894:PTPRA
gene id: 59894:PTPRA
uniprot id: U3JBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

59894:FAM49B
gene id: 59894:FAM49B
uniprot id: U3JIR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

59894:SLC25A14
gene id: 59894:SLC25A14
uniprot id: A0A803WER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:GATSL2
gene id: 59894:GATSL2
uniprot id: U3JX27
names: Similarity
messages: Belongs to the GATS family.

59894:NT5C3B
gene id: 59894:NT5C3B
uniprot id: U3JCZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

59894:C1H11orf87
gene id: 59894:C1H11orf87
uniprot id: A0A803VU00
names: Subcellular Location Annotation
messages: Membrane

59894:MEF2A
gene id: 59894:MEF2A
uniprot id: A0A803VKY5
uniprot id: A0A803W6G6
uniprot id: U3K6U1
names: Subcellular Location Annotation
messages: Nucleus

59894:MMRN1
gene id: 59894:MMRN1
uniprot id: U3JU70
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:SLC16A10
gene id: 59894:SLC16A10
uniprot id: U3K8F5
names: Subcellular Location Annotation
messages: Membrane

59894:LECT2
gene id: 59894:LECT2
uniprot id: U3K007
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

59894:TNFRSF6B
gene id: 59894:TNFRSF6B
uniprot id: U3JTN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:PDSS2
gene id: 59894:PDSS2
uniprot id: A0A803VWG6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

59894:CALHM2
gene id: 59894:CALHM2
uniprot id: U3K2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

59894:AGTR2
gene id: 59894:AGTR2
uniprot id: U3KJQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

59894:WDR82
gene id: 59894:WDR82
uniprot id: U3K2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

59894:POLA1
gene id: 59894:POLA1
uniprot id: U3JNC8
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

59894:ACMSD
gene id: 59894:ACMSD
uniprot id: A0A803V2Q1
uniprot id: A0A803W2W8
uniprot id: U3KH18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

59894:CCK
gene id: 59894:CCK
uniprot id: U3KCS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

59894:SUMO1
gene id: 59894:SUMO1
uniprot id: A0A803V4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

59894:MGST1
gene id: 59894:MGST1
uniprot id: A0A803WDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

59894:LOC101820209
gene id: 59894:LOC101820209
uniprot id: A0A803V323
names: Subcellular Location Annotation
messages: Membrane

59894:SHROOM1
gene id: 59894:SHROOM1
uniprot id: A0A803VI29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

59894:CHRNB4
gene id: 59894:CHRNB4
uniprot id: U3K7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:GABRQ
gene id: 59894:GABRQ
uniprot id: U3K972
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:PLD1
gene id: 59894:PLD1
uniprot id: U3K1D4
names: Similarity
messages: Belongs to the phospholipase D family.

59894:AHSA2
gene id: 59894:AHSA2
uniprot id: U3K900
names: Similarity
messages: Belongs to the AHA1 family.

59894:LOC101808317
gene id: 59894:LOC101808317
uniprot id: U3KKV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:MPP7
gene id: 59894:MPP7
uniprot id: A0A803VCX2
uniprot id: U3JXF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: adherens junction
messages: tight junction

59894:LOC101809259
gene id: 59894:LOC101809259
uniprot id: U3JIJ9
names: Similarity
messages: Belongs to the serpin family.

59894:P2RY1
gene id: 59894:P2RY1
uniprot id: U3KJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:CD44
gene id: 59894:CD44
uniprot id: A0A803V1V8
uniprot id: A0A803VZB8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

59894:LANCL1
gene id: 59894:LANCL1
uniprot id: U3KF45
names: Similarity
messages: Belongs to the LanC-like protein family.

59894:CDC5L
gene id: 59894:CDC5L
uniprot id: U3KDY3
names: Similarity
messages: Belongs to the CEF1 family.

59894:PTGFR
gene id: 59894:PTGFR
uniprot id: A0A803V7K6
uniprot id: A0A803VYS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:NXPH1
gene id: 59894:NXPH1
uniprot id: A0A803WBT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

59894:SEC23A
gene id: 59894:SEC23A
uniprot id: U3JUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

59894:GABRB1
gene id: 59894:GABRB1
uniprot id: U3JK16
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:IPO8
gene id: 59894:IPO8
uniprot id: A0A803W2L6
names: Subcellular Location Annotation
messages: Cytoplasm

59894:STXBP1
gene id: 59894:STXBP1
uniprot id: U3JSD4
uniprot id: U3JSE2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

59894:OGDH
gene id: 59894:OGDH
uniprot id: A0A803V864
uniprot id: A0A803VM64
uniprot id: A0A803VY84
uniprot id: U3JBA0
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

59894:PDX1
gene id: 59894:PDX1
uniprot id: U3K1Q7
names: Subcellular Location Annotation
messages: Nucleus

59894:SUPT4H1
gene id: 59894:SUPT4H1
uniprot id: A0A803W9P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus

59894:AKIRIN2
gene id: 59894:AKIRIN2
uniprot id: A0A803VTN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

59894:LOC101810386
gene id: 59894:LOC101810386
uniprot id: U3KH06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

59894:PSMC2
gene id: 59894:PSMC2
uniprot id: U3K746
names: Similarity
messages: Belongs to the AAA ATPase family.

59894:COPG2
gene id: 59894:COPG2
uniprot id: U3JRF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

59894:CHST1
gene id: 59894:CHST1
uniprot id: U3KIG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

59894:HOXD11
gene id: 59894:HOXD11
uniprot id: U3KIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

59894:ZMPSTE24
gene id: 59894:ZMPSTE24
uniprot id: U3JEA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

59894:CDKL1
gene id: 59894:CDKL1
uniprot id: A0A803V8C9
uniprot id: U3JGM0
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:NFKB1
gene id: 59894:NFKB1
uniprot id: U3K0E6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:MDK
gene id: 59894:MDK
uniprot id: U3JUR3
names: Similarity
messages: Belongs to the pleiotrophin family.

59894:DNAJA4
gene id: 59894:DNAJA4
uniprot id: U3K7S7
names: Subcellular Location Annotation
messages: Membrane

59894:TSPAN8
gene id: 59894:TSPAN8
uniprot id: U3K6T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:DUSP6
gene id: 59894:DUSP6
uniprot id: A0A803VPX5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

59894:EXOC1
gene id: 59894:EXOC1
uniprot id: A0A803V8R6
uniprot id: A0A803W1M2
uniprot id: A0A803W9V8
uniprot id: U3JM13
names: Similarity
messages: Belongs to the SEC3 family.

59894:SOD1
gene id: 59894:SOD1
uniprot id: U3K088
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

59894:RUNX3
gene id: 59894:RUNX3
uniprot id: U3JCH7
names: Subcellular Location Annotation
messages: Nucleus

59894:NLGN4X
gene id: 59894:NLGN4X
uniprot id: A0A803VEX7
uniprot id: U3JPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

59894:KIFC3
gene id: 59894:KIFC3
uniprot id: A0A803WCY7
uniprot id: U3JWP3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:TUBB1
gene id: 59894:TUBB1
uniprot id: A0A803VKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

59894:EDNRA
gene id: 59894:EDNRA
uniprot id: A0A803VXQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

59894:LOC101813935
gene id: 59894:LOC101813935
uniprot id: U3JR80
names: Similarity
messages: Belongs to the peptidase M14 family.

59894:ATP6V0C
gene id: 59894:ATP6V0C
uniprot id: A0A803V9I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

59894:LOC101819841
gene id: 59894:LOC101819841
uniprot id: U3JR61
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

59894:ACVRL1
gene id: 59894:ACVRL1
uniprot id: U3JBE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

59894:UTP18
gene id: 59894:UTP18
uniprot id: U3JFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

59894:TMEM258
gene id: 59894:TMEM258
uniprot id: U3KBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

59894:PLA2G12A
gene id: 59894:PLA2G12A
uniprot id: A0A803VKY8
names: Subcellular Location Annotation
messages: Secreted

59894:DCN
gene id: 59894:DCN
uniprot id: A0A803VLS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

59894:LACTB2
gene id: 59894:LACTB2
uniprot id: U3K156
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

59894:LCAT
gene id: 59894:LCAT
uniprot id: U3JXA9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

59894:CCZ1
gene id: 59894:CCZ1
uniprot id: A0A803V1X1
names: Similarity
messages: Belongs to the CCZ1 family.

59894:C3H6orf120
gene id: 59894:C3H6orf120
uniprot id: U3KLP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

59894:LOC101818642
gene id: 59894:LOC101818642
uniprot id: A0A803W4T2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:ARSK
gene id: 59894:ARSK
uniprot id: U3K385
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome

59894:OAT
gene id: 59894:OAT
uniprot id: U3JQB9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

59894:MTCH2
gene id: 59894:MTCH2
uniprot id: U3JF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:SPSB4
gene id: 59894:SPSB4
uniprot id: U3JW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

59894:LPAR4
gene id: 59894:LPAR4
uniprot id: U3KKI4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:GALNT15
gene id: 59894:GALNT15
uniprot id: A0A803V0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

59894:USP48
gene id: 59894:USP48
uniprot id: U3JM78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

59894:COX3
gene id: 59894:COX3
uniprot id: S0AU80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

59894:NRP1
gene id: 59894:NRP1
uniprot id: U3JXA7
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101812892
gene id: 59894:LOC101812892
uniprot id: U3KBT4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

59894:CLRN2
gene id: 59894:CLRN2
uniprot id: A0A803VTN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

59894:CHCHD6
gene id: 59894:CHCHD6
uniprot id: U3JZI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Membrane
messages: Mitochondrion inner membrane

59894:YPEL1
gene id: 59894:YPEL1
uniprot id: A0A803W4Z4
names: Similarity
messages: Belongs to the yippee family.

59894:LOC101808625
gene id: 59894:LOC101808625
uniprot id: A0A803W357
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

59894:SMPX
gene id: 59894:SMPX
uniprot id: U3JNK8
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

59894:LOC101807380
gene id: 59894:LOC101807380
uniprot id: U3KJQ9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:LOC101814521
gene id: 59894:LOC101814521
uniprot id: U3JMX3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

59894:TAF1D
gene id: 59894:TAF1D
uniprot id: U3JBZ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

59894:GPX7
gene id: 59894:GPX7
uniprot id: A0A803WDZ0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

59894:INTS10
gene id: 59894:INTS10
uniprot id: U3JVM8
uniprot id: U3JVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

59894:SEC22B
gene id: 59894:SEC22B
uniprot id: U3JLU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

59894:EXTL3
gene id: 59894:EXTL3
uniprot id: U3K8E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

59894:CPB2
gene id: 59894:CPB2
uniprot id: U3K0J5
names: Similarity
messages: Belongs to the peptidase M14 family.

59894:LOC101811856
gene id: 59894:LOC101811856
uniprot id: A0A803V104
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion.

59894:GPR155
gene id: 59894:GPR155
uniprot id: U3JK42
names: Subcellular Location Annotation
messages: Membrane

59894:VWA9
gene id: 59894:VWA9
uniprot id: U3K655
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

59894:AGPAT3
gene id: 59894:AGPAT3
uniprot id: A0A803VJ41
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

59894:ENKUR
gene id: 59894:ENKUR
uniprot id: A0A803V5U1
names: Subcellular Location Annotation
messages: cilium axoneme

59894:LOC101817738
gene id: 59894:LOC101817738
uniprot id: U3JLE8
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

59894:H3F3B
gene id: 59894:H3F3B
uniprot id: U3JE91
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:ZFX
gene id: 59894:ZFX
uniprot id: A0A803VG54
uniprot id: A0A803VSQ2
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101808279
gene id: 59894:LOC101808279
uniprot id: A0A803W4P6
uniprot id: U3KFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

59894:TJAP1
gene id: 59894:TJAP1
uniprot id: U3KC49
names: Subcellular Location Annotation
messages: Membrane

59894:NDUFB5
gene id: 59894:NDUFB5
uniprot id: A0A803VMC3
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

59894:CHST12
gene id: 59894:CHST12
uniprot id: A0A803WF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:NRDE2
gene id: 59894:NRDE2
uniprot id: U3KCP8
names: Similarity
messages: Belongs to the NRDE2 family.

59894:HTR5A
gene id: 59894:HTR5A
uniprot id: A0A803VEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:VPS37C
gene id: 59894:VPS37C
uniprot id: U3KC14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

59894:NCAPG
gene id: 59894:NCAPG
uniprot id: A0A803VZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

59894:SNX8
gene id: 59894:SNX8
uniprot id: A0A803VB01
uniprot id: U3KHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

59894:PHKB
gene id: 59894:PHKB
uniprot id: U3JBG6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

59894:ATP2C2
gene id: 59894:ATP2C2
uniprot id: U3JW43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:CCNE2
gene id: 59894:CCNE2
uniprot id: U3JSS4
names: Similarity
messages: Belongs to the cyclin family.

59894:RRAGD
gene id: 59894:RRAGD
uniprot id: U3JK33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

59894:CEP170B
gene id: 59894:CEP170B
uniprot id: U3JJZ4
names: Similarity
messages: Belongs to the CEP170 family.

59894:HOXA5
gene id: 59894:HOXA5
uniprot id: A0A803VJI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

59894:GPBP1
gene id: 59894:GPBP1
uniprot id: A0A803VFL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

59894:CCT8
gene id: 59894:CCT8
uniprot id: A0A803W3B9
uniprot id: U3JUZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

59894:CDC42EP1
gene id: 59894:CDC42EP1
uniprot id: U3KEH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

59894:CDH20
gene id: 59894:CDH20
uniprot id: U3KER3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:LOC101819425
gene id: 59894:LOC101819425
uniprot id: A0A803VXT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

59894:ADCYAP1R1
gene id: 59894:ADCYAP1R1
uniprot id: A0A803VKU4
uniprot id: U3JDR5
uniprot id: U3JDS0
names: Subcellular Location Annotation
messages: Membrane

59894:NFIA
gene id: 59894:NFIA
uniprot id: U3KD71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

59894:FOXS1
gene id: 59894:FOXS1
uniprot id: A0A803VK37
names: Subcellular Location Annotation
messages: Nucleus

59894:YPEL5
gene id: 59894:YPEL5
uniprot id: A0A803WD76
names: Similarity
messages: Belongs to the yippee family.

59894:CLGN
gene id: 59894:CLGN
uniprot id: A0A803V255
uniprot id: U3JQQ1
names: Similarity
messages: Belongs to the calreticulin family.

59894:PPP6R3
gene id: 59894:PPP6R3
uniprot id: A0A803VET0
uniprot id: A0A803W670
uniprot id: A0A803WGP3
names: Similarity
messages: Belongs to the SAPS family.

59894:CACNA2D2
gene id: 59894:CACNA2D2
uniprot id: U3K2Y2
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

59894:FAM3C
gene id: 59894:FAM3C
uniprot id: A0A803WCB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

59894:SUPV3L1
gene id: 59894:SUPV3L1
uniprot id: U3KF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

59894:PSMD13
gene id: 59894:PSMD13
uniprot id: A0A803V6J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

59894:RDH10
gene id: 59894:RDH10
uniprot id: U3K1L0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:HLCS
gene id: 59894:HLCS
uniprot id: U3JRP5
names: Similarity
messages: Belongs to the biotin--protein ligase family.

59894:LOC101813101
gene id: 59894:LOC101813101
uniprot id: U3KBU7
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

59894:CLDN18
gene id: 59894:CLDN18
uniprot id: A0A803VRY0
uniprot id: A0A803W130
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

59894:LOC101820568
gene id: 59894:LOC101820568
uniprot id: A0A803V313
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:DHRS7C
gene id: 59894:DHRS7C
uniprot id: U3JD65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:AMER3
gene id: 59894:AMER3
uniprot id: U3KJE0
names: Similarity
messages: Belongs to the Amer family.

59894:EXOC3
gene id: 59894:EXOC3
uniprot id: U3JQN6
names: Similarity
messages: Belongs to the SEC6 family.

59894:YAE1D1
gene id: 59894:YAE1D1
uniprot id: A0A803WF13
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:CALB2
gene id: 59894:CALB2
uniprot id: U3JXW7
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

59894:CRYAB
gene id: 59894:CRYAB
uniprot id: A0A803VPG7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

59894:TUBD1
gene id: 59894:TUBD1
uniprot id: U3JSN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Nucleus
messages: centriole
messages: cilium

59894:KCNS1
gene id: 59894:KCNS1
uniprot id: U3JS80
names: Subcellular Location Annotation
messages: Membrane

59894:CDADC1
gene id: 59894:CDADC1
uniprot id: U3K116
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

59894:PPRC1
gene id: 59894:PPRC1
uniprot id: U3K1E6
names: Subcellular Location Annotation
messages: Nucleus

59894:CASR
gene id: 59894:CASR
uniprot id: U3JQW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:PRPSAP1
gene id: 59894:PRPSAP1
uniprot id: U3JDY7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

59894:NASP
gene id: 59894:NASP
uniprot id: U3K4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

59894:LSS
gene id: 59894:LSS
uniprot id: U3KFR9
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

59894:POU6F2
gene id: 59894:POU6F2
uniprot id: A0A803W250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

59894:PRPF4
gene id: 59894:PRPF4
uniprot id: A0A803VX82
names: Subcellular Location Annotation
messages: Nucleus speckle

59894:SMC1B
gene id: 59894:SMC1B
uniprot id: A0A803W7M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

59894:FGF18
gene id: 59894:FGF18
uniprot id: U3JKZ2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

59894:CTSD
gene id: 59894:CTSD
uniprot id: A0A803W730
names: Similarity
messages: Belongs to the peptidase A1 family.

59894:MB
gene id: 59894:MB
uniprot id: U3KF95
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

59894:ABCG8
gene id: 59894:ABCG8
uniprot id: U3KE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

59894:SLC7A5
gene id: 59894:SLC7A5
uniprot id: A0A803WAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

59894:AMH
gene id: 59894:AMH
uniprot id: A0A803VYW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

59894:DNAAF1
gene id: 59894:DNAAF1
uniprot id: A0A803VEP4
uniprot id: U3JYX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
messages: cilium

59894:LLGL1
gene id: 59894:LLGL1
uniprot id: U3KH40
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

59894:LOC101820830
gene id: 59894:LOC101820830
uniprot id: U3JYN8
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

59894:TOLLIP
gene id: 59894:TOLLIP
uniprot id: A0A803V6G1
uniprot id: A0A803VZZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

59894:MPI
gene id: 59894:MPI
uniprot id: U3K8I2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

59894:WNT11
gene id: 59894:WNT11
uniprot id: U3JUN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:GPR156
gene id: 59894:GPR156
uniprot id: U3JRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

59894:CLTB
gene id: 59894:CLTB
uniprot id: U3K1N0
uniprot id: U3K1N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

59894:QPCT
gene id: 59894:QPCT
uniprot id: U3KB49
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

59894:HAUS3
gene id: 59894:HAUS3
uniprot id: U3K5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

59894:GATA4
gene id: 59894:GATA4
uniprot id: A0A803VPC6
names: Subcellular Location Annotation
messages: Nucleus

59894:MYBL1
gene id: 59894:MYBL1
uniprot id: A0A803VJL6
uniprot id: U3JSB1
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101819070
gene id: 59894:LOC101819070
uniprot id: U3KB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

59894:MTFR2
gene id: 59894:MTFR2
uniprot id: U3KEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

59894:SLC16A7
gene id: 59894:SLC16A7
uniprot id: U3JY00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

59894:MTNR1B
gene id: 59894:MTNR1B
uniprot id: U3JBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:ING1
gene id: 59894:ING1
uniprot id: U3JP61
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

59894:LTN1
gene id: 59894:LTN1
uniprot id: U3JUZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

59894:EIF4ENIF1
gene id: 59894:EIF4ENIF1
uniprot id: U3JYA1
names: Subcellular Location Annotation
messages: Cytoplasm

59894:RPS6KB1
gene id: 59894:RPS6KB1
uniprot id: U3JSM2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

59894:SLC5A8
gene id: 59894:SLC5A8
uniprot id: U3K9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

59894:CERS6
gene id: 59894:CERS6
uniprot id: U3JDC3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

59894:LOC101817781
gene id: 59894:LOC101817781
uniprot id: U3KDP9
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:MFGE8
gene id: 59894:MFGE8
uniprot id: U3K7A9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:RHPN2
gene id: 59894:RHPN2
uniprot id: U3JBW9
names: Similarity
messages: Belongs to the RHPN family.

59894:MAP3K9
gene id: 59894:MAP3K9
uniprot id: A0A803W787
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

59894:GBF1
gene id: 59894:GBF1
uniprot id: A0A803W840
names: Subcellular Location Annotation
messages: Golgi apparatus

59894:LOC101810802
gene id: 59894:LOC101810802
uniprot id: U3KBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

59894:KIAA1191
gene id: 59894:KIAA1191
uniprot id: U3K1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

59894:NDRG4
gene id: 59894:NDRG4
uniprot id: A0A803V599
uniprot id: A0A803VTN6
uniprot id: U3JWJ6
names: Similarity
messages: Belongs to the NDRG family.

59894:TSPAN5
gene id: 59894:TSPAN5
uniprot id: U3JUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:GDNF
gene id: 59894:GDNF
uniprot id: U3JH73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

59894:L3MBTL1
gene id: 59894:L3MBTL1
uniprot id: U3KE81
names: Subcellular Location Annotation
messages: Nucleus

59894:TRAM2
gene id: 59894:TRAM2
uniprot id: A0A803V835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

59894:LAMC2
gene id: 59894:LAMC2
uniprot id: U3JK44
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

59894:SLC23A3
gene id: 59894:SLC23A3
uniprot id: U3JNK1
names: Subcellular Location Annotation
messages: Membrane

59894:ADD1
gene id: 59894:ADD1
uniprot id: A0A803VAQ2
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

59894:LOC101810537
gene id: 59894:LOC101810537
uniprot id: A0A803W491
names: Similarity
messages: Belongs to the serpin family.

59894:HENMT1
gene id: 59894:HENMT1
uniprot id: U3JJ27
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

59894:SLC4A3
gene id: 59894:SLC4A3
uniprot id: U3JP30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

59894:ABCC9
gene id: 59894:ABCC9
uniprot id: A0A803V1K6
uniprot id: A0A803V5P9
uniprot id: A0A803VE12
uniprot id: U3JLS9
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

59894:NHSL1
gene id: 59894:NHSL1
uniprot id: A0A803V160
uniprot id: A0A803VFB3
uniprot id: U3KEE3
names: Similarity
messages: Belongs to the NHS family.

59894:DIEXF
gene id: 59894:DIEXF
uniprot id: U3KDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

59894:DNA2
gene id: 59894:DNA2
uniprot id: U3KEU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

59894:CDH2
gene id: 59894:CDH2
uniprot id: U3JU31
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:HSD17B2
gene id: 59894:HSD17B2
uniprot id: U3JW65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:CHGB
gene id: 59894:CHGB
uniprot id: A0A803V1B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

59894:DICER1
gene id: 59894:DICER1
uniprot id: U3JIM7
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

59894:POMGNT2
gene id: 59894:POMGNT2
uniprot id: U3KIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:FSIP1
gene id: 59894:FSIP1
uniprot id: A0A803V8E8
names: Similarity
messages: Belongs to the FSIP1 family.

59894:TCEA2
gene id: 59894:TCEA2
uniprot id: U3K6Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

59894:ADCK1
gene id: 59894:ADCK1
uniprot id: U3KDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

59894:LOC101818392
gene id: 59894:LOC101818392
uniprot id: U3JNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

59894:IL4R
gene id: 59894:IL4R
uniprot id: A0A803V8Q3
uniprot id: A0A803WGR3
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

59894:COQ4
gene id: 59894:COQ4
uniprot id: U3JF63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

59894:FOXL2
gene id: 59894:FOXL2
uniprot id: U3KL56
names: Subcellular Location Annotation
messages: Nucleus

59894:GPRC5C
gene id: 59894:GPRC5C
uniprot id: A0A803W071
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:NKIRAS2
gene id: 59894:NKIRAS2
uniprot id: A0A803VEW6
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

59894:NIPAL2
gene id: 59894:NIPAL2
uniprot id: U3JT56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

59894:ARG2
gene id: 59894:ARG2
uniprot id: U3JRF6
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

59894:KIF12
gene id: 59894:KIF12
uniprot id: U3JVG6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:PRPF19
gene id: 59894:PRPF19
uniprot id: U3KC60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

59894:DHDDS
gene id: 59894:DHDDS
uniprot id: A0A803VU61
names: Similarity
messages: Belongs to the UPP synthase family.

59894:UROC1
gene id: 59894:UROC1
uniprot id: U3KDR9
names: Similarity
messages: Belongs to the urocanase family.

59894:ADRA1A
gene id: 59894:ADRA1A
uniprot id: U3K9X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: caveola

59894:MAT2A
gene id: 59894:MAT2A
uniprot id: U3JBF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

59894:UNC5C
gene id: 59894:UNC5C
uniprot id: A0A803VKJ6
uniprot id: A0A803VMX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

59894:SUSD2
gene id: 59894:SUSD2
uniprot id: U3K0S9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101815220
gene id: 59894:LOC101815220
uniprot id: A0A803VZC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

59894:SLC25A25
gene id: 59894:SLC25A25
uniprot id: A0A803VH74
uniprot id: A0A803VMJ6
uniprot id: A0A803W3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

59894:PGM2
gene id: 59894:PGM2
uniprot id: U3K3X8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

59894:TSHR
gene id: 59894:TSHR
uniprot id: A0A803V609
uniprot id: A0A803VBU8
uniprot id: A0A803VL14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

59894:IRF2
gene id: 59894:IRF2
uniprot id: U3KB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

59894:BFSP1
gene id: 59894:BFSP1
uniprot id: U3KGV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

59894:PLOD1
gene id: 59894:PLOD1
uniprot id: U3K618
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

59894:PCSK1
gene id: 59894:PCSK1
uniprot id: A0A803VZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

59894:ING3
gene id: 59894:ING3
uniprot id: U3K5V4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

59894:SCOC
gene id: 59894:SCOC
uniprot id: A0A803VN81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

59894:CTNNA1
gene id: 59894:CTNNA1
uniprot id: A0A803VZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

59894:LOC101810145
gene id: 59894:LOC101810145
uniprot id: U3JC49
names: Similarity
messages: Belongs to the intermediate filament family.

59894:NME7
gene id: 59894:NME7
uniprot id: A0A803VAE1
uniprot id: A0A803VJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

59894:DEGS2
gene id: 59894:DEGS2
uniprot id: A0A803W495
uniprot id: A0A803W4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane

59894:SLC34A2
gene id: 59894:SLC34A2
uniprot id: U3K3G8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

59894:EYA2
gene id: 59894:EYA2
uniprot id: U3JRC8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

59894:C8A
gene id: 59894:C8A
uniprot id: U3KCT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:C1H11orf54
gene id: 59894:C1H11orf54
uniprot id: U3JBZ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

59894:SVOPL
gene id: 59894:SVOPL
uniprot id: U3K335
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101810346
gene id: 59894:LOC101810346
uniprot id: U3KKS0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:ARCN1
gene id: 59894:ARCN1
uniprot id: U3K5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

59894:DAG1
gene id: 59894:DAG1
uniprot id: U3K2Z0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

59894:PPT1
gene id: 59894:PPT1
uniprot id: U3JCN1
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

59894:LOC101816585
gene id: 59894:LOC101816585
uniprot id: U3JXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

59894:PACSIN2
gene id: 59894:PACSIN2
uniprot id: A0A803V8L9
uniprot id: U3JW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

59894:LOC101811954
gene id: 59894:LOC101811954
uniprot id: A0A803W5M8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

59894:ABL1
gene id: 59894:ABL1
uniprot id: A0A803V5V2
uniprot id: U3JFF5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:CENPN
gene id: 59894:CENPN
uniprot id: A0A803VY48
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

59894:LNPEP
gene id: 59894:LNPEP
uniprot id: A0A803VD44
uniprot id: U3JE02
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

59894:LOC101819804
gene id: 59894:LOC101819804
uniprot id: A0A803VSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

59894:PLTP
gene id: 59894:PLTP
uniprot id: U3JPU4
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

59894:NEUROD1
gene id: 59894:NEUROD1
uniprot id: U3KLI5
names: Subcellular Location Annotation
messages: Nucleus

59894:XPNPEP1
gene id: 59894:XPNPEP1
uniprot id: A0A803V187
names: Similarity
messages: Belongs to the peptidase M24B family.

59894:GPR161
gene id: 59894:GPR161
uniprot id: U3JT86
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:COPB2
gene id: 59894:COPB2
uniprot id: U3JNA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

59894:EFNB2
gene id: 59894:EFNB2
uniprot id: U3JNP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:GJA4
gene id: 59894:GJA4
uniprot id: U3KIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:LOC101815467
gene id: 59894:LOC101815467
uniprot id: U3K8N5
names: Subcellular Location Annotation
messages: Membrane

59894:NKIRAS1
gene id: 59894:NKIRAS1
uniprot id: A0A803W135
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

59894:DDOST
gene id: 59894:DDOST
uniprot id: U3JLW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

59894:ZWILCH
gene id: 59894:ZWILCH
uniprot id: U3KEA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

59894:GPM6A
gene id: 59894:GPM6A
uniprot id: A0A803WGN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

59894:GJA5
gene id: 59894:GJA5
uniprot id: U3KJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:SLC26A9
gene id: 59894:SLC26A9
uniprot id: U3JCV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane.
messages: Membrane

59894:TP63
gene id: 59894:TP63
uniprot id: A0A803VMQ3
uniprot id: U3JY64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Nucleus

59894:WNT6
gene id: 59894:WNT6
uniprot id: A0A803WDE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:PDE6H
gene id: 59894:PDE6H
uniprot id: U3K9U0
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

59894:NKAIN3
gene id: 59894:NKAIN3
uniprot id: U3JSL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

59894:LOC101806839
gene id: 59894:LOC101806839
uniprot id: A0A803VHL9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

59894:NR2F2
gene id: 59894:NR2F2
uniprot id: A0A803VIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:UTP3
gene id: 59894:UTP3
uniprot id: U3KJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAS10 family.
messages: nucleolus

59894:POSTN
gene id: 59894:POSTN
uniprot id: A0A803V3C1
uniprot id: A0A803VM61
uniprot id: A0A803VVY2
uniprot id: A0A803VZJ1
uniprot id: A0A803W823
uniprot id: U3K0P5
uniprot id: U3K0P6
names: Subcellular Location Annotation
messages: extracellular matrix

59894:LOC101817341
gene id: 59894:LOC101817341
uniprot id: U3JLA3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

59894:MAN1A2
gene id: 59894:MAN1A2
uniprot id: U3JQZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

59894:LOC101811383
gene id: 59894:LOC101811383
uniprot id: U3JSG8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

59894:CCNJ
gene id: 59894:CCNJ
uniprot id: A0A803VSF2
names: Similarity
messages: Belongs to the cyclin family.

59894:CDR2L
gene id: 59894:CDR2L
uniprot id: U3JEU3
names: Similarity
messages: Belongs to the CDR2 family.

59894:OLFM1
gene id: 59894:OLFM1
uniprot id: U3JG48
uniprot id: U3JG49
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

59894:NOP14
gene id: 59894:NOP14
uniprot id: U3K5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

59894:FUT10
gene id: 59894:FUT10
uniprot id: U3JRC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

59894:LOC101806551
gene id: 59894:LOC101806551
uniprot id: U3KB63
names: Subcellular Location Annotation
messages: Secreted

59894:ARPC1B
gene id: 59894:ARPC1B
uniprot id: U3KHB0
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

59894:ABCG5
gene id: 59894:ABCG5
uniprot id: U3KE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

59894:RAB18
gene id: 59894:RAB18
uniprot id: A0A803VMQ5
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

59894:NCK2
gene id: 59894:NCK2
uniprot id: A0A803V237
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

59894:RAF1
gene id: 59894:RAF1
uniprot id: U3JB65
uniprot id: U3JB66
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

59894:WT1
gene id: 59894:WT1
uniprot id: A0A803V9F4
uniprot id: A0A803W5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

59894:CORIN
gene id: 59894:CORIN
uniprot id: U3JK73
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101817211
gene id: 59894:LOC101817211
uniprot id: A0A803WFM7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:NUDT2
gene id: 59894:NUDT2
uniprot id: A0A803W348
names: Similarity
messages: Belongs to the Nudix hydrolase family.

59894:PTPN4
gene id: 59894:PTPN4
uniprot id: A0A803VT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

59894:MED27
gene id: 59894:MED27
uniprot id: U3JFG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

59894:ATP6V1C2
gene id: 59894:ATP6V1C2
uniprot id: A0A803W645
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

59894:LOC101808641
gene id: 59894:LOC101808641
uniprot id: A0A803V8G2
uniprot id: U3JF55
names: Subcellular Location Annotation
messages: Nucleus

59894:ANKRD13A
gene id: 59894:ANKRD13A
uniprot id: A0A803VCT9
uniprot id: U3K200
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

59894:BTK
gene id: 59894:BTK
uniprot id: U3KA25
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:FAM171B
gene id: 59894:FAM171B
uniprot id: U3JPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

59894:DYNC2LI1
gene id: 59894:DYNC2LI1
uniprot id: A0A803VWW1
uniprot id: U3KE12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

59894:RAD52
gene id: 59894:RAD52
uniprot id: U3JMX6
names: Similarity
messages: Belongs to the RAD52 family.

59894:TRPM3
gene id: 59894:TRPM3
uniprot id: U3K8F4
names: Subcellular Location Annotation
messages: Membrane

59894:HAL
gene id: 59894:HAL
uniprot id: A0A803V5Z7
names: Similarity
messages: Belongs to the PAL/histidase family.

59894:SAR1B
gene id: 59894:SAR1B
uniprot id: U3JZS1
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

59894:UBA3
gene id: 59894:UBA3
uniprot id: U3KFZ2
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

59894:LOC101809793
gene id: 59894:LOC101809793
uniprot id: U3JIK0
names: Similarity
messages: Belongs to the serpin family.

59894:HOXA10
gene id: 59894:HOXA10
uniprot id: U3K473
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

59894:LOC101816143
gene id: 59894:LOC101816143
uniprot id: U3JCR1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101816855
gene id: 59894:LOC101816855
uniprot id: U3JTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

59894:SCMH1
gene id: 59894:SCMH1
uniprot id: U3JEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

59894:INIP
gene id: 59894:INIP
uniprot id: A0A803VLE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

59894:LOC101815170
gene id: 59894:LOC101815170
uniprot id: A0A803VAY6
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:UCKL1
gene id: 59894:UCKL1
uniprot id: A0A803WEF6
names: Similarity
messages: Belongs to the uridine kinase family.

59894:LOC101811991
gene id: 59894:LOC101811991
uniprot id: U3KL17
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

59894:C4AHXorf56
gene id: 59894:C4AHXorf56
uniprot id: U3JFW0
names: Similarity
messages: Belongs to the STEEP1 family.

59894:LOC101813370
gene id: 59894:LOC101813370
uniprot id: U3KJV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:COQ5
gene id: 59894:COQ5
uniprot id: A0A803VSK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

59894:TMEM175
gene id: 59894:TMEM175
uniprot id: A0A803VMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

59894:STK4
gene id: 59894:STK4
uniprot id: U3JS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

59894:LOC101808110
gene id: 59894:LOC101808110
uniprot id: A0A803V0H4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

59894:PRKCE
gene id: 59894:PRKCE
uniprot id: A0A803WBA8
uniprot id: U3KES8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

59894:SAP18
gene id: 59894:SAP18
uniprot id: A0A803V4P6
names: Similarity
messages: Belongs to the SAP18 family.

59894:LOC101814878
gene id: 59894:LOC101814878
uniprot id: U3KFA9
names: Similarity
messages: Belongs to the hexokinase family.

59894:EXOC6
gene id: 59894:EXOC6
uniprot id: U3JZP9
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

59894:SDR42E1
gene id: 59894:SDR42E1
uniprot id: A0A803V6G8
names: Similarity
messages: Belongs to the 3-beta-HSD family.

59894:LOC101807840
gene id: 59894:LOC101807840
uniprot id: U3JW15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

59894:TNFRSF19
gene id: 59894:TNFRSF19
uniprot id: U3K217
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:MRPL43
gene id: 59894:MRPL43
uniprot id: A0A803VKV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

59894:TNMD
gene id: 59894:TNMD
uniprot id: U3JMS6
names: Similarity
messages: Belongs to the chondromodulin-1 family.

59894:CDC42EP3
gene id: 59894:CDC42EP3
uniprot id: U3KLJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

59894:LOC101819009
gene id: 59894:LOC101819009
uniprot id: U3JJI2
names: Similarity
messages: Belongs to the peptidase C1 family.

59894:LOC101807405
gene id: 59894:LOC101807405
uniprot id: U3JCL3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:P2RY2
gene id: 59894:P2RY2
uniprot id: U3KJD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:CCDC181
gene id: 59894:CCDC181
uniprot id: A0A803W097
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton

59894:PPIP5K1
gene id: 59894:PPIP5K1
uniprot id: A0A803VE09
uniprot id: A0A803VH72
uniprot id: A0A803WFJ1
uniprot id: U3KA05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

59894:RNF146
gene id: 59894:RNF146
uniprot id: U3KLM2
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

59894:ENPP2
gene id: 59894:ENPP2
uniprot id: U3JI40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

59894:C15H12orf65
gene id: 59894:C15H12orf65
uniprot id: U3K3Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

59894:B4GALT2
gene id: 59894:B4GALT2
uniprot id: U3JRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

59894:SMPDL3B
gene id: 59894:SMPDL3B
uniprot id: U3JEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Secreted

59894:LOC101818345
gene id: 59894:LOC101818345
uniprot id: U3JEI8
names: Similarity
messages: Belongs to the perilipin family.

59894:LOC101822253
gene id: 59894:LOC101822253
uniprot id: A0A803W0H9
names: Similarity
messages: Belongs to the GroES chaperonin family.

59894:SEC31A
gene id: 59894:SEC31A
uniprot id: A0A803W5K3
uniprot id: U3JT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

59894:LOC101818850
gene id: 59894:LOC101818850
uniprot id: U3JWK2
names: Similarity
messages: Belongs to the dpy-30 family.

59894:CTSA
gene id: 59894:CTSA
uniprot id: U3JPR2
names: Similarity
messages: Belongs to the peptidase S10 family.

59894:GALNT4
gene id: 59894:GALNT4
uniprot id: U3KK81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

59894:RHBG
gene id: 59894:RHBG
uniprot id: U3JL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

59894:LOC101821752
gene id: 59894:LOC101821752
uniprot id: A0A803W1C1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

59894:GLRA1
gene id: 59894:GLRA1
uniprot id: U3K0Q5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

59894:TERF2IP
gene id: 59894:TERF2IP
uniprot id: U3JIS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

59894:MAPK9
gene id: 59894:MAPK9
uniprot id: U3JZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

59894:SNCA
gene id: 59894:SNCA
uniprot id: A0A803VUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

59894:TEC
gene id: 59894:TEC
uniprot id: U3JKF9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:ST6GAL1
gene id: 59894:ST6GAL1
uniprot id: U3JN27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:VPS54
gene id: 59894:VPS54
uniprot id: A0A803VQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

59894:ARL3
gene id: 59894:ARL3
uniprot id: A0A803V9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

59894:LOC101821137
gene id: 59894:LOC101821137
uniprot id: U3KB34
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:LOC101811710
gene id: 59894:LOC101811710
uniprot id: U3KE09
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101806455
gene id: 59894:LOC101806455
uniprot id: U3KLL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:SLC17A6
gene id: 59894:SLC17A6
uniprot id: U3JQB8
names: Subcellular Location Annotation
messages: Membrane

59894:L3MBTL3
gene id: 59894:L3MBTL3
uniprot id: A0A803VY53
names: Subcellular Location Annotation
messages: Nucleus

59894:TNFRSF8
gene id: 59894:TNFRSF8
uniprot id: U3K5X7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:RTN1
gene id: 59894:RTN1
uniprot id: A0A803VPV8
uniprot id: U3JLG2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:MYH9
gene id: 59894:MYH9
uniprot id: U3KF79
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

59894:RAB3GAP1
gene id: 59894:RAB3GAP1
uniprot id: A0A803WBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm
messages: Endoplasmic reticulum

59894:SWI5
gene id: 59894:SWI5
uniprot id: A0A803VG18
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

59894:LOC101814202
gene id: 59894:LOC101814202
uniprot id: U3K6K6
names: Similarity
messages: Belongs to the peptidase A1 family.

59894:TFCP2L1
gene id: 59894:TFCP2L1
uniprot id: U3KFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

59894:ELF3
gene id: 59894:ELF3
uniprot id: U3JJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:NMNAT1
gene id: 59894:NMNAT1
uniprot id: A0A803WDU1
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

59894:RGS12
gene id: 59894:RGS12
uniprot id: U3K540
names: Subcellular Location Annotation
messages: Cytoplasm

59894:CREB1
gene id: 59894:CREB1
uniprot id: A0A803VJN6
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101815857
gene id: 59894:LOC101815857
uniprot id: U3JY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

59894:CDH12
gene id: 59894:CDH12
uniprot id: U3JYQ4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:SEMA5A
gene id: 59894:SEMA5A
uniprot id: U3JZG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101815555
gene id: 59894:LOC101815555
uniprot id: U3JET8
names: Subcellular Location Annotation
messages: Membrane

59894:USP9X
gene id: 59894:USP9X
uniprot id: U3JFP5
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:GDF15
gene id: 59894:GDF15
uniprot id: U3K498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

59894:MAPK8
gene id: 59894:MAPK8
uniprot id: U3JYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

59894:CDC42
gene id: 59894:CDC42
uniprot id: A0A803WGM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

59894:MTNR1A
gene id: 59894:MTNR1A
uniprot id: A0A803V2X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LOC101811547
gene id: 59894:LOC101811547
uniprot id: U3JKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

59894:FAM124A
gene id: 59894:FAM124A
uniprot id: U3K1A3
names: Similarity
messages: Belongs to the FAM124 family.

59894:ILDR1
gene id: 59894:ILDR1
uniprot id: U3JTU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

59894:BUD31
gene id: 59894:BUD31
uniprot id: U3KHA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

59894:CA4
gene id: 59894:CA4
uniprot id: A0A803VPY0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

59894:PDGFB
gene id: 59894:PDGFB
uniprot id: U3KD28
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

59894:PHKA1
gene id: 59894:PHKA1
uniprot id: U3KBV4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

59894:SURF6
gene id: 59894:SURF6
uniprot id: U3JFK2
names: Similarity
messages: Belongs to the SURF6 family.

59894:PHACTR2
gene id: 59894:PHACTR2
uniprot id: A0A803VYG8
uniprot id: U3KE00
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

59894:GJC2
gene id: 59894:GJC2
uniprot id: U3KK00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:BRCC3
gene id: 59894:BRCC3
uniprot id: U3KAZ1
names: Similarity
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.

59894:RIMBP2
gene id: 59894:RIMBP2
uniprot id: U3K4I4
names: Similarity
messages: Belongs to the RIMBP family.

59894:DCLK3
gene id: 59894:DCLK3
uniprot id: U3JJP2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

59894:METAP2
gene id: 59894:METAP2
uniprot id: A0A803W9S1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

59894:LOC101819490
gene id: 59894:LOC101819490
uniprot id: U3KJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:MAT1A
gene id: 59894:MAT1A
uniprot id: U3JWK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

59894:LOC101817434
gene id: 59894:LOC101817434
uniprot id: U3JLP3
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Interacts with MAPK8IP2.

59894:RORB
gene id: 59894:RORB
uniprot id: A0A803VCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:SMC5
gene id: 59894:SMC5
uniprot id: A0A803V3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

59894:CHRND
gene id: 59894:CHRND
uniprot id: U3JZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:USP1
gene id: 59894:USP1
uniprot id: U3KDE3
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:HSD3B7
gene id: 59894:HSD3B7
uniprot id: U3K419
names: Similarity
messages: Belongs to the 3-beta-HSD family.

59894:HMGCL
gene id: 59894:HMGCL
uniprot id: A0A803W454
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

59894:LOC101815920
gene id: 59894:LOC101815920
uniprot id: U3KC86
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

59894:FAM167A
gene id: 59894:FAM167A
uniprot id: A0A803VNM2
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

59894:LOC101817565
gene id: 59894:LOC101817565
uniprot id: U3KI83
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:RAX2
gene id: 59894:RAX2
uniprot id: U3KB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

59894:GARS
gene id: 59894:GARS
uniprot id: A0A803VLP0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

59894:NFIC
gene id: 59894:NFIC
uniprot id: U3KAK1
uniprot id: U3KAK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

59894:CD38
gene id: 59894:CD38
uniprot id: U3K3U0
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

59894:SEMA6D
gene id: 59894:SEMA6D
uniprot id: A0A803VUY7
uniprot id: A0A803W1Q6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101811814
gene id: 59894:LOC101811814
uniprot id: U3KJD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LOC101817530
gene id: 59894:LOC101817530
uniprot id: A0A803V6P6
uniprot id: U3KBM8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:TXLNA
gene id: 59894:TXLNA
uniprot id: U3JCX8
names: Similarity
messages: Belongs to the taxilin family.

59894:ABR
gene id: 59894:ABR
uniprot id: U3JUE5
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

59894:OPRM1
gene id: 59894:OPRM1
uniprot id: U3KD51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

59894:DIS3L2
gene id: 59894:DIS3L2
uniprot id: U3JYX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

59894:TMEM56
gene id: 59894:TMEM56
uniprot id: U3JI65
names: Subcellular Location Annotation
messages: Membrane

59894:TAAR1
gene id: 59894:TAAR1
uniprot id: A0A803W1E0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:CPLX2
gene id: 59894:CPLX2
uniprot id: A0A803VDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

59894:PSMA6
gene id: 59894:PSMA6
uniprot id: U3JU26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus

59894:HABP2
gene id: 59894:HABP2
uniprot id: U3JHU1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:LOC101818425
gene id: 59894:LOC101818425
uniprot id: U3K731
names: Similarity
messages: Belongs to the CRISP family.

59894:MCTP2
gene id: 59894:MCTP2
uniprot id: U3K705
names: Subcellular Location Annotation
messages: Membrane

59894:GMDS
gene id: 59894:GMDS
uniprot id: A0A803V3H7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

59894:EXOSC2
gene id: 59894:EXOSC2
uniprot id: U3JFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

59894:WDFY1
gene id: 59894:WDFY1
uniprot id: A0A803V4N5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

59894:ENKD1
gene id: 59894:ENKD1
uniprot id: U3JWW1
names: Subcellular Location Annotation
messages: cilium axoneme

59894:SERPINF1
gene id: 59894:SERPINF1
uniprot id: U3JVT3
names: Similarity
messages: Belongs to the serpin family.

59894:NPY1R
gene id: 59894:NPY1R
uniprot id: U3K9A1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:ENY2
gene id: 59894:ENY2
uniprot id: U3JUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

59894:TNFSF15
gene id: 59894:TNFSF15
uniprot id: U3JS18
names: Similarity
messages: Belongs to the tumor necrosis factor family.

59894:ACTR8
gene id: 59894:ACTR8
uniprot id: A0A803W7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

59894:EGFL7
gene id: 59894:EGFL7
uniprot id: U3JG62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:POU2F3
gene id: 59894:POU2F3
uniprot id: U3JU14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

59894:WDR35
gene id: 59894:WDR35
uniprot id: U3JGE7
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

59894:LOC101819238
gene id: 59894:LOC101819238
uniprot id: U3JG41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

59894:PRLR
gene id: 59894:PRLR
uniprot id: U3JHD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

59894:SMG8
gene id: 59894:SMG8
uniprot id: U3JSU5
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

59894:FRG1
gene id: 59894:FRG1
uniprot id: U3K9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

59894:LOC101818482
gene id: 59894:LOC101818482
uniprot id: U3KLM9
names: Subunit
messages: Interacts with ATP6V0C.

59894:GEM
gene id: 59894:GEM
uniprot id: U3JSC4
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

59894:TPRA1
gene id: 59894:TPRA1
uniprot id: U3JZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

59894:POT1
gene id: 59894:POT1
uniprot id: A0A803WAV6
uniprot id: U3K5H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

59894:CAV3
gene id: 59894:CAV3
uniprot id: A0A803WE76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

59894:WARS
gene id: 59894:WARS
uniprot id: U3JJ57
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

59894:DPH6
gene id: 59894:DPH6
uniprot id: A0A803UZY1
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

59894:CLCN7
gene id: 59894:CLCN7
uniprot id: U3JNL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

59894:FGF12
gene id: 59894:FGF12
uniprot id: A0A803V5E3
uniprot id: U3JXY0
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

59894:TUSC5
gene id: 59894:TUSC5
uniprot id: U3JUE9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

59894:AMDHD2
gene id: 59894:AMDHD2
uniprot id: U3JQK5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

59894:TMEM63A
gene id: 59894:TMEM63A
uniprot id: U3KAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

59894:COQ7
gene id: 59894:COQ7
uniprot id: A0A803V8T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

59894:ARAP1
gene id: 59894:ARAP1
uniprot id: U3JUR2
names: Subcellular Location Annotation
messages: Cytoplasm

59894:NPBWR2
gene id: 59894:NPBWR2
uniprot id: U3KKL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:SYNDIG1L
gene id: 59894:SYNDIG1L
uniprot id: U3JUV2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

59894:UBE4A
gene id: 59894:UBE4A
uniprot id: U3K5X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

59894:OSBPL2
gene id: 59894:OSBPL2
uniprot id: U3K7P4
names: Similarity
messages: Belongs to the OSBP family.

59894:XRCC5
gene id: 59894:XRCC5
uniprot id: U3JMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase.

59894:STAT4
gene id: 59894:STAT4
uniprot id: A0A803W1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

59894:LOC101809406
gene id: 59894:LOC101809406
uniprot id: U3KGG9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

59894:DYRK4
gene id: 59894:DYRK4
uniprot id: U3JGW0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

59894:SLC2A12
gene id: 59894:SLC2A12
uniprot id: A0A803VT47
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:ASRGL1
gene id: 59894:ASRGL1
uniprot id: A0A803W920
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

59894:SFRP4
gene id: 59894:SFRP4
uniprot id: A0A803WAM2
uniprot id: U3JJJ5
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:BIRC2
gene id: 59894:BIRC2
uniprot id: U3JC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

59894:RCAN3
gene id: 59894:RCAN3
uniprot id: U3JCJ3
names: Similarity
messages: Belongs to the RCAN family.

59894:LOC101809482
gene id: 59894:LOC101809482
uniprot id: U3JSX4
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101813295
gene id: 59894:LOC101813295
uniprot id: U3K4J0
names: Similarity
messages: Belongs to the folate receptor family.

59894:EEF1B2
gene id: 59894:EEF1B2
uniprot id: U3JMP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

59894:ARHGEF3
gene id: 59894:ARHGEF3
uniprot id: A0A803VX28
uniprot id: A0A803WG95
uniprot id: U3K1I1
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

59894:ST18
gene id: 59894:ST18
uniprot id: A0A803VR75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

59894:ACOX2
gene id: 59894:ACOX2
uniprot id: U3KFG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

59894:SMC2
gene id: 59894:SMC2
uniprot id: U3JBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

59894:KCNE4
gene id: 59894:KCNE4
uniprot id: U3KLC2
names: Similarity
messages: Belongs to the potassium channel KCNE family.

59894:LOC101820045
gene id: 59894:LOC101820045
uniprot id: U3K6W5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

59894:LOC101817496
gene id: 59894:LOC101817496
uniprot id: U3K5Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

59894:RAB27A
gene id: 59894:RAB27A
uniprot id: A0A803V1N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

59894:TNFRSF21
gene id: 59894:TNFRSF21
uniprot id: U3JFT3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:GABRG2
gene id: 59894:GABRG2
uniprot id: U3KGH9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:MICAL2
gene id: 59894:MICAL2
uniprot id: A0A803WG89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

59894:BCAT1
gene id: 59894:BCAT1
uniprot id: A0A803V737
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

59894:NR1D2
gene id: 59894:NR1D2
uniprot id: U3K3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:RNMT
gene id: 59894:RNMT
uniprot id: U3JVF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

59894:HSD17B12
gene id: 59894:HSD17B12
uniprot id: U3KD30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:AGO4
gene id: 59894:AGO4
uniprot id: A0A803VPC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

59894:CUL2
gene id: 59894:CUL2
uniprot id: A0A803VBM8
names: Similarity
messages: Belongs to the cullin family.

59894:CDK2AP1
gene id: 59894:CDK2AP1
uniprot id: A0A803VML3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

59894:TNFSF13B
gene id: 59894:TNFSF13B
uniprot id: U3JNM9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

59894:AGTPBP1
gene id: 59894:AGTPBP1
uniprot id: A0A803VJU3
uniprot id: U3JLV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

59894:GOLPH3L
gene id: 59894:GOLPH3L
uniprot id: A0A803VHH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

59894:CABIN1
gene id: 59894:CABIN1
uniprot id: A0A803VUD3
uniprot id: U3JXQ2
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101821448
gene id: 59894:LOC101821448
uniprot id: U3JSA8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

59894:CNOT6
gene id: 59894:CNOT6
uniprot id: A0A803V476
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

59894:LOC101813401
gene id: 59894:LOC101813401
uniprot id: U3KKV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:NDUFAF1
gene id: 59894:NDUFAF1
uniprot id: A0A803V036
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

59894:KPNA3
gene id: 59894:KPNA3
uniprot id: U3K157
names: Similarity
messages: Belongs to the importin alpha family.

59894:ADD3
gene id: 59894:ADD3
uniprot id: A0A803VBB6
uniprot id: U3JI08
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

59894:SLC29A4
gene id: 59894:SLC29A4
uniprot id: U3KHD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

59894:NXT2
gene id: 59894:NXT2
uniprot id: U3JBN0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

59894:IL18R1
gene id: 59894:IL18R1
uniprot id: U3JM45
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

59894:HNRNPDL
gene id: 59894:HNRNPDL
uniprot id: U3JT46
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:SLC8A3
gene id: 59894:SLC8A3
uniprot id: A0A803V2N5
uniprot id: A0A803WGG0
uniprot id: U3JQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

59894:BCHE
gene id: 59894:BCHE
uniprot id: U3K1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

59894:COLGALT2
gene id: 59894:COLGALT2
uniprot id: U3JKB9
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

59894:SLC12A8
gene id: 59894:SLC12A8
uniprot id: U3KGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

59894:VWC2
gene id: 59894:VWC2
uniprot id: A0A803W0F6
names: Subcellular Location Annotation
messages: Synapse

59894:CLIC5
gene id: 59894:CLIC5
uniprot id: U3JFK3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

59894:PIK3R1
gene id: 59894:PIK3R1
uniprot id: A0A803V3M1
uniprot id: A0A803VZJ0
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

59894:GAPDH
gene id: 59894:GAPDH
uniprot id: A0A803W110
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC.
messages: Homotetramer.
messages: cytosol

59894:PPP2R2A
gene id: 59894:PPP2R2A
uniprot id: A0A803WA87
uniprot id: A0A803WER0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

59894:ND4L
gene id: 59894:ND4L
uniprot id: S0AT24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

59894:FNIP1
gene id: 59894:FNIP1
uniprot id: U3JE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

59894:LOC101806163
gene id: 59894:LOC101806163
uniprot id: A0A803V4W7
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

59894:NDE1
gene id: 59894:NDE1
uniprot id: U3KI17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

59894:MAB21L1
gene id: 59894:MAB21L1
uniprot id: A0A803W1X8
names: Similarity
messages: Belongs to the mab-21 family.

59894:NDOR1
gene id: 59894:NDOR1
uniprot id: A0A803WDB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

59894:PTPRF
gene id: 59894:PTPRF
uniprot id: A0A803VI66
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

59894:HCRT
gene id: 59894:HCRT
uniprot id: U3KLG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

59894:FNIP2
gene id: 59894:FNIP2
uniprot id: A0A803VMD4
uniprot id: A0A803WCF6
uniprot id: U3JK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

59894:LARP7
gene id: 59894:LARP7
uniprot id: A0A803VW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

59894:LOC101806046
gene id: 59894:LOC101806046
uniprot id: U3KAH5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

59894:TMEM181
gene id: 59894:TMEM181
uniprot id: U3KDR4
names: Subcellular Location Annotation
messages: Membrane

59894:TGM4
gene id: 59894:TGM4
uniprot id: U3JIU2
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

59894:GPAT4
gene id: 59894:GPAT4
uniprot id: U3JVA5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

59894:TRNAU1AP
gene id: 59894:TRNAU1AP
uniprot id: U3JF73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

59894:CC2D1B
gene id: 59894:CC2D1B
uniprot id: U3JSQ5
names: Similarity
messages: Belongs to the CC2D1 family.

59894:BRINP2
gene id: 59894:BRINP2
uniprot id: U3K0S6
names: Similarity
messages: Belongs to the BRINP family.

59894:PPP1R9A
gene id: 59894:PPP1R9A
uniprot id: A0A803VN46
uniprot id: A0A803VXV0
uniprot id: A0A803WFE7
uniprot id: U3K6X2
names: Subcellular Location Annotation
messages: cytoskeleton

59894:HACD2
gene id: 59894:HACD2
uniprot id: A0A803VGE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:PDK1
gene id: 59894:PDK1
uniprot id: A0A803WAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

59894:FGD4
gene id: 59894:FGD4
uniprot id: A0A803V3J1
names: Subcellular Location Annotation
messages: cytoskeleton

59894:CNOT1
gene id: 59894:CNOT1
uniprot id: A0A803V0X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

59894:EP300
gene id: 59894:EP300
uniprot id: U3KC15
names: Subcellular Location Annotation
messages: Cytoplasm

59894:INTS8
gene id: 59894:INTS8
uniprot id: U3JSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

59894:ACKR3
gene id: 59894:ACKR3
uniprot id: U3KL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:CUL1
gene id: 59894:CUL1
uniprot id: U3K6V8
names: Similarity
messages: Belongs to the cullin family.

59894:FGF8
gene id: 59894:FGF8
uniprot id: A0A803VJP4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

59894:TCEANC
gene id: 59894:TCEANC
uniprot id: U3KL82
names: Subcellular Location Annotation
messages: Nucleus

59894:AHSA1
gene id: 59894:AHSA1
uniprot id: U3KDX3
names: Similarity
messages: Belongs to the AHA1 family.

59894:ORC4
gene id: 59894:ORC4
uniprot id: A0A803WFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

59894:CRYAA
gene id: 59894:CRYAA
uniprot id: U3JH28
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

59894:P2RY4
gene id: 59894:P2RY4
uniprot id: U3KKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LOC101811926
gene id: 59894:LOC101811926
uniprot id: U3JZG4
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

59894:MFNG
gene id: 59894:MFNG
uniprot id: A0A803VXM6
names: Subcellular Location Annotation
messages: Membrane

59894:PAX5
gene id: 59894:PAX5
uniprot id: A0A803VEZ6
uniprot id: U3KEV4
names: Subcellular Location Annotation
messages: Nucleus

59894:CKB
gene id: 59894:CKB
uniprot id: A0A803VF24
uniprot id: U3JJL5
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

59894:LAPTM4B
gene id: 59894:LAPTM4B
uniprot id: A0A803WA76
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

59894:PIGZ
gene id: 59894:PIGZ
uniprot id: U3JXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:FAM83F
gene id: 59894:FAM83F
uniprot id: U3KCJ5
names: Similarity
messages: Belongs to the FAM83 family.

59894:CPNE1
gene id: 59894:CPNE1
uniprot id: A0A803WDD8
uniprot id: U3KDF2
names: Similarity
messages: Belongs to the copine family.

59894:DGKK
gene id: 59894:DGKK
uniprot id: A0A803VI52
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

59894:FAM46D
gene id: 59894:FAM46D
uniprot id: U3KKD3
names: Similarity
messages: Belongs to the TENT family.

59894:HEPHL1
gene id: 59894:HEPHL1
uniprot id: A0A803VB58
names: Similarity
messages: Belongs to the multicopper oxidase family.

59894:TSSC4
gene id: 59894:TSSC4
uniprot id: U3KJ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

59894:ODF2L
gene id: 59894:ODF2L
uniprot id: U3JUU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

59894:LOC101811934
gene id: 59894:LOC101811934
uniprot id: U3JC30
names: Similarity
messages: Belongs to the intermediate filament family.

59894:CLIC4
gene id: 59894:CLIC4
uniprot id: U3JCI0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

59894:GJD4
gene id: 59894:GJD4
uniprot id: A0A803VPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:MMP2
gene id: 59894:MMP2
uniprot id: U3JZN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

59894:ASPHD2
gene id: 59894:ASPHD2
uniprot id: U3K1H5
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

59894:UPF2
gene id: 59894:UPF2
uniprot id: A0A803VBX0
names: Subcellular Location Annotation
messages: Cytoplasm

59894:FAM134B
gene id: 59894:FAM134B
uniprot id: A0A803W8S5
uniprot id: A0A803WF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:ADGRA1
gene id: 59894:ADGRA1
uniprot id: U3K009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

59894:PIGF
gene id: 59894:PIGF
uniprot id: U3KEJ3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:NIT2
gene id: 59894:NIT2
uniprot id: U3JTN4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

59894:ACTB
gene id: 59894:ACTB
uniprot id: U3KHC4
names: Similarity
messages: Belongs to the actin family.

59894:LIN54
gene id: 59894:LIN54
uniprot id: A0A803VW85
uniprot id: U3JSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

59894:ETS2
gene id: 59894:ETS2
uniprot id: A0A803WEA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcription factor.

59894:CORO2B
gene id: 59894:CORO2B
uniprot id: U3K6E2
names: Similarity
messages: Belongs to the WD repeat coronin family.

59894:TLR7
gene id: 59894:TLR7
uniprot id: U3JPF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

59894:SRM
gene id: 59894:SRM
uniprot id: U3K6S8
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

59894:MCM3
gene id: 59894:MCM3
uniprot id: U3JHC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

59894:PTGES3
gene id: 59894:PTGES3
uniprot id: U3JCD6
names: Similarity
messages: Belongs to the p23/wos2 family.

59894:ICT1
gene id: 59894:ICT1
uniprot id: U3JEU2
names: Subcellular Location Annotation
messages: Mitochondrion

59894:PPM1K
gene id: 59894:PPM1K
uniprot id: U3JS49
names: Similarity
messages: Belongs to the PP2C family.

59894:LOC101813950
gene id: 59894:LOC101813950
uniprot id: U3JR15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:LOC101805746
gene id: 59894:LOC101805746
uniprot id: A0A803WGD0
names: Subcellular Location Annotation
messages: cytoskeleton

59894:TNFRSF11A
gene id: 59894:TNFRSF11A
uniprot id: A0A803VHH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:SLC5A12
gene id: 59894:SLC5A12
uniprot id: A0A803WG58
uniprot id: U3JK54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

59894:NPSR1
gene id: 59894:NPSR1
uniprot id: U3JJ82
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:ALDH3A2
gene id: 59894:ALDH3A2
uniprot id: A0A803VBJ5
uniprot id: A0A803W156
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

59894:PTGR2
gene id: 59894:PTGR2
uniprot id: U3JSL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

59894:CA7
gene id: 59894:CA7
uniprot id: U3JZ42
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

59894:PKN2
gene id: 59894:PKN2
uniprot id: U3JFZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

59894:AK5
gene id: 59894:AK5
uniprot id: U3JT41
names: Similarity
messages: Belongs to the adenylate kinase family.

59894:IL2RG
gene id: 59894:IL2RG
uniprot id: A0A803VCC6
names: Subcellular Location Annotation
messages: Membrane

59894:NDC80
gene id: 59894:NDC80
uniprot id: U3JUT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

59894:SAXO2
gene id: 59894:SAXO2
uniprot id: A0A803W6L9
names: Similarity
messages: Belongs to the FAM154 family.

59894:DLGAP3
gene id: 59894:DLGAP3
uniprot id: U3JD96
names: Similarity
messages: Belongs to the SAPAP family.

59894:LETM1
gene id: 59894:LETM1
uniprot id: U3K5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

59894:TMEM163
gene id: 59894:TMEM163
uniprot id: U3KH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

59894:HOXD10
gene id: 59894:HOXD10
uniprot id: U3JKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

59894:BCR
gene id: 59894:BCR
uniprot id: A0A803VE73
uniprot id: U3JY17
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

59894:C2H8orf37
gene id: 59894:C2H8orf37
uniprot id: A0A803VR57
uniprot id: U3JSU8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

59894:ZP3
gene id: 59894:ZP3
uniprot id: U3KCP3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

59894:CNN2
gene id: 59894:CNN2
uniprot id: U3KHU0
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

59894:DPAGT1
gene id: 59894:DPAGT1
uniprot id: U3K5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:ADAMTS18
gene id: 59894:ADAMTS18
uniprot id: U3JC10
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

59894:VAMP4
gene id: 59894:VAMP4
uniprot id: A0A803W0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

59894:LOC101810599
gene id: 59894:LOC101810599
uniprot id: A0A803VGY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

59894:LOC101818796
gene id: 59894:LOC101818796
uniprot id: U3JZ58
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

59894:LOC101806037
gene id: 59894:LOC101806037
uniprot id: A0A803WEJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b5 family.
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

59894:NFE2L2
gene id: 59894:NFE2L2
uniprot id: U3JKR4
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

59894:TVP23B
gene id: 59894:TVP23B
uniprot id: U3K4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

59894:DCLK1
gene id: 59894:DCLK1
uniprot id: A0A803V2R1
uniprot id: U3K0X9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

59894:UBP1
gene id: 59894:UBP1
uniprot id: U3JQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

59894:PDZD2
gene id: 59894:PDZD2
uniprot id: U3JHK1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homotetramer.
messages: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
messages: Nucleus
messages: Secreted

59894:LOC101806016
gene id: 59894:LOC101806016
uniprot id: U3JCA5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

59894:SPSB3
gene id: 59894:SPSB3
uniprot id: A0A803V021
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

59894:LOC101809163
gene id: 59894:LOC101809163
uniprot id: U3JPK9
names: Similarity
messages: Belongs to the intermediate filament family.

59894:CECR1
gene id: 59894:CECR1
uniprot id: U3JK00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

59894:FAM110B
gene id: 59894:FAM110B
uniprot id: U3KK97
names: Similarity
messages: Belongs to the FAM110 family.

59894:KCNC1
gene id: 59894:KCNC1
uniprot id: U3JDC5
names: Subcellular Location Annotation
messages: Membrane

59894:A2M
gene id: 59894:A2M
uniprot id: U3JY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

59894:CWC15
gene id: 59894:CWC15
uniprot id: A0A803W3A7
names: Similarity
messages: Belongs to the CWC15 family.

59894:TPM3
gene id: 59894:TPM3
uniprot id: A0A803W3D6
uniprot id: U3JEM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

59894:SLC25A32
gene id: 59894:SLC25A32
uniprot id: U3JTX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:LOC101807389
gene id: 59894:LOC101807389
uniprot id: U3JBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

59894:CSF1R
gene id: 59894:CSF1R
uniprot id: U3JZS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

59894:UIMC1
gene id: 59894:UIMC1
uniprot id: A0A803VNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

59894:HLF
gene id: 59894:HLF
uniprot id: U3JHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

59894:SLC6A14
gene id: 59894:SLC6A14
uniprot id: U3JGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:OSBPL9
gene id: 59894:OSBPL9
uniprot id: A0A803VMM7
uniprot id: U3JSE7
names: Similarity
messages: Belongs to the OSBP family.

59894:NUP62CL
gene id: 59894:NUP62CL
uniprot id: U3K9P3
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

59894:ADORA2A
gene id: 59894:ADORA2A
uniprot id: A0A803VML4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

59894:LOC101805866
gene id: 59894:LOC101805866
uniprot id: U3KKT9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:SERPINH1
gene id: 59894:SERPINH1
uniprot id: U3JVT8
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

59894:THRB
gene id: 59894:THRB
uniprot id: U3K3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

59894:METAP1D
gene id: 59894:METAP1D
uniprot id: A0A803VGL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

59894:FOXJ1
gene id: 59894:FOXJ1
uniprot id: U3JE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

59894:LOC101806491
gene id: 59894:LOC101806491
uniprot id: U3JXI4
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:LOC101819248
gene id: 59894:LOC101819248
uniprot id: U3KIK7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:LOC101816410
gene id: 59894:LOC101816410
uniprot id: U3K2V7
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

59894:SLC12A1
gene id: 59894:SLC12A1
uniprot id: A0A803VF84
uniprot id: A0A803VFE3
uniprot id: U3KAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

59894:DARS
gene id: 59894:DARS
uniprot id: U3KH56
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

59894:RGR
gene id: 59894:RGR
uniprot id: U3JWD9
names: Subcellular Location Annotation
messages: Membrane

59894:CAB39
gene id: 59894:CAB39
uniprot id: A0A803VN76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

59894:DYNC1I2
gene id: 59894:DYNC1I2
uniprot id: A0A803VI14
uniprot id: U3JH23
names: Similarity
messages: Belongs to the dynein intermediate chain family.

59894:GDF2
gene id: 59894:GDF2
uniprot id: A0A803W295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

59894:IL2RB
gene id: 59894:IL2RB
uniprot id: A0A803VPU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

59894:SLC41A2
gene id: 59894:SLC41A2
uniprot id: A0A803VY27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

59894:RPL3
gene id: 59894:RPL3
uniprot id: U3KD18
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

59894:CSNK1G1
gene id: 59894:CSNK1G1
uniprot id: A0A803V2X2
uniprot id: A0A803W0R8
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

59894:SET
gene id: 59894:SET
uniprot id: A0A803VMM4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

59894:LOC101816865
gene id: 59894:LOC101816865
uniprot id: U3JDQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

59894:PIGW
gene id: 59894:PIGW
uniprot id: U3KKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

59894:CTNND1
gene id: 59894:CTNND1
uniprot id: A0A803VMK1
names: Similarity
messages: Belongs to the beta-catenin family.

59894:PABPC4
gene id: 59894:PABPC4
uniprot id: A0A803WA61
uniprot id: U3JCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

59894:UBE2E3
gene id: 59894:UBE2E3
uniprot id: U3JLL8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

59894:DBNDD2
gene id: 59894:DBNDD2
uniprot id: A0A803V6B0
names: Similarity
messages: Belongs to the dysbindin family.

59894:RPL18A
gene id: 59894:RPL18A
uniprot id: U3K5Q7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

59894:TRIP12
gene id: 59894:TRIP12
uniprot id: U3JWW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: nucleoplasm

59894:TEX10
gene id: 59894:TEX10
uniprot id: U3JQL2
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

59894:DBX1
gene id: 59894:DBX1
uniprot id: U3JG39
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101819517
gene id: 59894:LOC101819517
uniprot id: U3K2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

59894:SYN3
gene id: 59894:SYN3
uniprot id: U3KFP8
names: Similarity
messages: Belongs to the synapsin family.

59894:SF3B3
gene id: 59894:SF3B3
uniprot id: U3JY42
names: Subcellular Location Annotation
messages: Nucleus

59894:TAT
gene id: 59894:TAT
uniprot id: U3JIT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

59894:MED30
gene id: 59894:MED30
uniprot id: U3JI03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

59894:UNG
gene id: 59894:UNG
uniprot id: U3K2H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

59894:MGAT5
gene id: 59894:MGAT5
uniprot id: U3KH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

59894:PAQR9
gene id: 59894:PAQR9
uniprot id: A0A803VFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

59894:GUK1
gene id: 59894:GUK1
uniprot id: U3JEB5
names: Similarity
messages: Belongs to the guanylate kinase family.

59894:CNTNAP4
gene id: 59894:CNTNAP4
uniprot id: U3KD33
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:GPR158
gene id: 59894:GPR158
uniprot id: U3JXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:DYRK3
gene id: 59894:DYRK3
uniprot id: U3JCS8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

59894:IL13RA1
gene id: 59894:IL13RA1
uniprot id: U3JG64
names: Subcellular Location Annotation
messages: Membrane

59894:ZP1
gene id: 59894:ZP1
uniprot id: U3KC80
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:GRK4
gene id: 59894:GRK4
uniprot id: U3K5B5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

59894:AFF1
gene id: 59894:AFF1
uniprot id: U3JSP0
names: Similarity
messages: Belongs to the AF4 family.

59894:PSMC3
gene id: 59894:PSMC3
uniprot id: U3JV66
names: Similarity
messages: Belongs to the AAA ATPase family.

59894:PSPC1
gene id: 59894:PSPC1
uniprot id: U3K275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

59894:GPR157
gene id: 59894:GPR157
uniprot id: U3JY19
names: Subcellular Location Annotation
messages: Membrane

59894:CLCN4
gene id: 59894:CLCN4
uniprot id: A0A803VJZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

59894:SUPT3H
gene id: 59894:SUPT3H
uniprot id: U3KDX2
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101815505
gene id: 59894:LOC101815505
uniprot id: A0A803VZN8
uniprot id: U3JY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

59894:SLC25A40
gene id: 59894:SLC25A40
uniprot id: A0A803VMV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:CHRM4
gene id: 59894:CHRM4
uniprot id: U3KIG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

59894:GNG4
gene id: 59894:GNG4
uniprot id: U3KGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

59894:LOC101819468
gene id: 59894:LOC101819468
uniprot id: U3KF08
names: Similarity
messages: Belongs to the serpin family.

59894:CDH22
gene id: 59894:CDH22
uniprot id: U3JQH5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:THNSL2
gene id: 59894:THNSL2
uniprot id: U3K6H6
names: Similarity
messages: Belongs to the threonine synthase family.

59894:SPON1
gene id: 59894:SPON1
uniprot id: U3K832
names: Subcellular Location Annotation
messages: extracellular matrix

59894:DRAM2
gene id: 59894:DRAM2
uniprot id: A0A803W1N7
names: Subcellular Location Annotation
messages: Membrane

59894:HTATSF1
gene id: 59894:HTATSF1
uniprot id: U3JM88
names: Similarity
messages: Belongs to the HTATSF1 family.

59894:CNR1
gene id: 59894:CNR1
uniprot id: A0A803V3N1
uniprot id: A0A803VM53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

59894:LOC101809697
gene id: 59894:LOC101809697
uniprot id: U3K5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

59894:RNASEH1
gene id: 59894:RNASEH1
uniprot id: A0A803WFL2
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

59894:LOC101809845
gene id: 59894:LOC101809845
uniprot id: U3K1U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

59894:MAD1L1
gene id: 59894:MAD1L1
uniprot id: A0A803VP15
uniprot id: A0A803W0H7
uniprot id: U3KHL5
names: Similarity
messages: Belongs to the MAD1 family.

59894:HYAL3
gene id: 59894:HYAL3
uniprot id: A0A803WEL6
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

59894:PARP8
gene id: 59894:PARP8
uniprot id: A0A803W8I6
uniprot id: U3K9S4
names: Similarity
messages: Belongs to the ARTD/PARP family.

59894:NINJ2
gene id: 59894:NINJ2
uniprot id: U3JMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

59894:FGF7
gene id: 59894:FGF7
uniprot id: A0A803VCF6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

59894:RAB43
gene id: 59894:RAB43
uniprot id: A0A803VCD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

59894:PSMD1
gene id: 59894:PSMD1
uniprot id: U3JYM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

59894:IDH1
gene id: 59894:IDH1
uniprot id: U3JLZ0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

59894:UNC93A
gene id: 59894:UNC93A
uniprot id: U3KCY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

59894:CMTM3
gene id: 59894:CMTM3
uniprot id: U3JYX2
names: Subcellular Location Annotation
messages: Membrane

59894:KIAA1024L
gene id: 59894:KIAA1024L
uniprot id: U3JQK2
names: Similarity
messages: Belongs to the MINAR family.

59894:SMG6
gene id: 59894:SMG6
uniprot id: U3JVL4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

59894:NUP58
gene id: 59894:NUP58
uniprot id: A0A803VWY7
uniprot id: U3K204
uniprot id: U3K205
names: Subcellular Location Annotation
messages: nuclear pore complex

59894:LOC101812909
gene id: 59894:LOC101812909
uniprot id: A0A803VZD0
names: Subcellular Location Annotation
messages: cytoskeleton

59894:TWSG1
gene id: 59894:TWSG1
uniprot id: A0A803WBT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

59894:LOC101815990
gene id: 59894:LOC101815990
uniprot id: A0A803V6F1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

59894:CLPS
gene id: 59894:CLPS
uniprot id: U3JLU0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

59894:GSPT1
gene id: 59894:GSPT1
uniprot id: U3JMP0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

59894:NEU2
gene id: 59894:NEU2
uniprot id: U3KGF1
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

59894:ZDHHC16
gene id: 59894:ZDHHC16
uniprot id: U3K198
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:LOC101811319
gene id: 59894:LOC101811319
uniprot id: A0A803V7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

59894:LOC101817769
gene id: 59894:LOC101817769
uniprot id: U3JNL1
names: Similarity
messages: Belongs to the sulfatase family.

59894:LAPTM5
gene id: 59894:LAPTM5
uniprot id: U3JEV2
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

59894:LOC101810536
gene id: 59894:LOC101810536
uniprot id: U3KFU2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

59894:FDFT1
gene id: 59894:FDFT1
uniprot id: U3JIK8
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

59894:TEAD1
gene id: 59894:TEAD1
uniprot id: A0A803W3I7
names: Subcellular Location Annotation
messages: Nucleus

59894:FAM161A
gene id: 59894:FAM161A
uniprot id: U3K8V8
names: Similarity
messages: Belongs to the FAM161 family.

59894:LOC101814109
gene id: 59894:LOC101814109
uniprot id: U3JL78
names: Subcellular Location Annotation
messages: Membrane

59894:XRCC3
gene id: 59894:XRCC3
uniprot id: U3JJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

59894:SIAH1
gene id: 59894:SIAH1
uniprot id: U3JBF4
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

59894:WDR48
gene id: 59894:WDR48
uniprot id: U3JW27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

59894:SCNN1B
gene id: 59894:SCNN1B
uniprot id: U3KI21
names: Subcellular Location Annotation
messages: Membrane

59894:PDCD10
gene id: 59894:PDCD10
uniprot id: A0A803VNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

59894:ACADL
gene id: 59894:ACADL
uniprot id: U3KF69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

59894:AGTR1
gene id: 59894:AGTR1
uniprot id: U3KLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

59894:LRRC8D
gene id: 59894:LRRC8D
uniprot id: U3KKM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

59894:MDFIC
gene id: 59894:MDFIC
uniprot id: A0A803W8N8
uniprot id: U3K6B9
names: Similarity
messages: Belongs to the MDFI family.

59894:ITM2B
gene id: 59894:ITM2B
uniprot id: A0A803W685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

59894:LOC101814445
gene id: 59894:LOC101814445
uniprot id: U3JLM2
names: Similarity
messages: Belongs to the FBPase class 1 family.

59894:CNOT7
gene id: 59894:CNOT7
uniprot id: A0A803WA75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

59894:VGLL1
gene id: 59894:VGLL1
uniprot id: A0A803V0R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

59894:TYR
gene id: 59894:TYR
uniprot id: U3JZL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

59894:TBC1D7
gene id: 59894:TBC1D7
uniprot id: U3KG05
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

59894:LEPROT
gene id: 59894:LEPROT
uniprot id: U3KE13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

59894:USP35
gene id: 59894:USP35
uniprot id: A0A803W0S3
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:CHST13
gene id: 59894:CHST13
uniprot id: A0A803V3M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:FAM49A
gene id: 59894:FAM49A
uniprot id: A0A803V9N4
uniprot id: A0A803W574
uniprot id: U3K209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

59894:ST3GAL3
gene id: 59894:ST3GAL3
uniprot id: A0A803V6K6
uniprot id: A0A803VJW0
uniprot id: A0A803VSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:KIAA0430
gene id: 59894:KIAA0430
uniprot id: U3KI18
names: Subcellular Location Annotation
messages: Peroxisome

59894:LOC101812848
gene id: 59894:LOC101812848
uniprot id: U3JWL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101812933
gene id: 59894:LOC101812933
uniprot id: U3JND7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

59894:IRF8
gene id: 59894:IRF8
uniprot id: U3JVY3
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101806376
gene id: 59894:LOC101806376
uniprot id: U3JXK0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:GHRH
gene id: 59894:GHRH
uniprot id: A0A803V535
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

59894:RSPO1
gene id: 59894:RSPO1
uniprot id: A0A803V063
names: Similarity
messages: Belongs to the R-spondin family.

59894:MBTD1
gene id: 59894:MBTD1
uniprot id: U3JFB2
names: Subcellular Location Annotation
messages: Nucleus

59894:SGSM2
gene id: 59894:SGSM2
uniprot id: U3JQ99
names: Similarity
messages: Belongs to the RUTBC family.

59894:UTRN
gene id: 59894:UTRN
uniprot id: A0A803V8F7
uniprot id: A0A803W8P9
uniprot id: U3KF18
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

59894:LOC101809285
gene id: 59894:LOC101809285
uniprot id: U3KHA8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

59894:EIF4A2
gene id: 59894:EIF4A2
uniprot id: U3K0M2
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

59894:LOC101806070
gene id: 59894:LOC101806070
uniprot id: U3JXJ8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:FHL5
gene id: 59894:FHL5
uniprot id: A0A803VQX4
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

59894:AK8
gene id: 59894:AK8
uniprot id: U3JFI3
names: Similarity
messages: Belongs to the adenylate kinase family.

59894:SLC7A6
gene id: 59894:SLC7A6
uniprot id: A0A803VD81
names: Subcellular Location Annotation
messages: Membrane

59894:CCNG2
gene id: 59894:CCNG2
uniprot id: U3K1G1
names: Similarity
messages: Belongs to the cyclin family.

59894:ENO4
gene id: 59894:ENO4
uniprot id: U3JHP3
names: Similarity
messages: Belongs to the enolase family.

59894:CZH18orf25
gene id: 59894:CZH18orf25
uniprot id: U3K2L5
names: Subcellular Location Annotation
messages: Nucleus

59894:KLHL40
gene id: 59894:KLHL40
uniprot id: A0A803VH08
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

59894:SYPL1
gene id: 59894:SYPL1
uniprot id: A0A803V5W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

59894:KMO
gene id: 59894:KMO
uniprot id: U3KFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

59894:ADNP
gene id: 59894:ADNP
uniprot id: A0A803VKX6
names: Subcellular Location Annotation
messages: Nucleus

59894:NIPA2
gene id: 59894:NIPA2
uniprot id: A0A803VFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

59894:SDPR
gene id: 59894:SDPR
uniprot id: U3JP13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

59894:AZIN1
gene id: 59894:AZIN1
uniprot id: U3JTR1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

59894:AIMP2
gene id: 59894:AIMP2
uniprot id: A0A803V315
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

59894:ANKRD13B
gene id: 59894:ANKRD13B
uniprot id: A0A803WBS0
uniprot id: U3JUQ0
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

59894:GFRA1
gene id: 59894:GFRA1
uniprot id: U3JHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

59894:MAN1A1
gene id: 59894:MAN1A1
uniprot id: A0A803VPW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

59894:MRPL42
gene id: 59894:MRPL42
uniprot id: U3K829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

59894:TMEM178B
gene id: 59894:TMEM178B
uniprot id: U3JMF0
names: Similarity
messages: Belongs to the TMEM178 family.

59894:YTHDF1
gene id: 59894:YTHDF1
uniprot id: U3K7B1
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

59894:RER1
gene id: 59894:RER1
uniprot id: A0A803V3T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

59894:TGFB2
gene id: 59894:TGFB2
uniprot id: U3KCJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

59894:ZNF592
gene id: 59894:ZNF592
uniprot id: U3K5N5
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

59894:CNEP1R1
gene id: 59894:CNEP1R1
uniprot id: A0A803VHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

59894:TMCC3
gene id: 59894:TMCC3
uniprot id: U3K863
names: Similarity
messages: Belongs to the TEX28 family.

59894:STC2
gene id: 59894:STC2
uniprot id: A0A803VMA4
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

59894:KCNA10
gene id: 59894:KCNA10
uniprot id: A0A803W9Q2
names: Subcellular Location Annotation
messages: Membrane

59894:SNX33
gene id: 59894:SNX33
uniprot id: U3K880
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

59894:LOC101810052
gene id: 59894:LOC101810052
uniprot id: U3JLM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

59894:LOC101818037
gene id: 59894:LOC101818037
uniprot id: U3K4N4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

59894:SMC3
gene id: 59894:SMC3
uniprot id: U3JHZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

59894:IL17REL
gene id: 59894:IL17REL
uniprot id: U3K4W9
names: Subcellular Location Annotation
messages: Cell membrane

59894:TMSB4X
gene id: 59894:TMSB4X
uniprot id: A0A803W5X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

59894:HSPA8
gene id: 59894:HSPA8
uniprot id: U3JTG3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

59894:QRSL1
gene id: 59894:QRSL1
uniprot id: U3KAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

59894:RAB32
gene id: 59894:RAB32
uniprot id: U3KF61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

59894:LOC101817239
gene id: 59894:LOC101817239
uniprot id: A0A803V5A2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

59894:IL31RA
gene id: 59894:IL31RA
uniprot id: U3K8P5
names: Subcellular Location Annotation
messages: Membrane

59894:EXT2
gene id: 59894:EXT2
uniprot id: U3KCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

59894:DFNB59
gene id: 59894:DFNB59
uniprot id: U3JL98
names: Similarity
messages: Belongs to the gasdermin family.

59894:KPNA6
gene id: 59894:KPNA6
uniprot id: U3JCX6
names: Similarity
messages: Belongs to the importin alpha family.

59894:SLC7A13
gene id: 59894:SLC7A13
uniprot id: A0A803W6B0
names: Subcellular Location Annotation
messages: Membrane

59894:SEPT2
gene id: 59894:SEPT2
uniprot id: U3JLB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

59894:GLE1
gene id: 59894:GLE1
uniprot id: A0A803VVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

59894:USP7
gene id: 59894:USP7
uniprot id: A0A803V8K4
uniprot id: U3JN08
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:ESF1
gene id: 59894:ESF1
uniprot id: U3K8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

59894:TMEM159
gene id: 59894:TMEM159
uniprot id: U3KHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

59894:LOC101812552
gene id: 59894:LOC101812552
uniprot id: A0A803VZ29
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

59894:SLC25A19
gene id: 59894:SLC25A19
uniprot id: A0A803V5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:LSM3
gene id: 59894:LSM3
uniprot id: U3KDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

59894:TMEM27
gene id: 59894:TMEM27
uniprot id: A0A803VSN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:SGMS2
gene id: 59894:SGMS2
uniprot id: U3KCW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

59894:DUOXA2
gene id: 59894:DUOXA2
uniprot id: A0A803W4W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

59894:EBF2
gene id: 59894:EBF2
uniprot id: U3K9L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

59894:SLC16A6
gene id: 59894:SLC16A6
uniprot id: A0A803W7Y5
names: Subcellular Location Annotation
messages: Membrane

59894:CRAT
gene id: 59894:CRAT
uniprot id: U3JFD7
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

59894:SYBU
gene id: 59894:SYBU
uniprot id: U3JUE8
names: Subcellular Location Annotation
messages: Membrane

59894:LPCAT1
gene id: 59894:LPCAT1
uniprot id: U3JHJ1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

59894:CAPN6
gene id: 59894:CAPN6
uniprot id: U3K956
names: Similarity
messages: Belongs to the peptidase C2 family.

59894:ENO2
gene id: 59894:ENO2
uniprot id: U3JQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

59894:RPL15
gene id: 59894:RPL15
uniprot id: A0A803WET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

59894:ACER2
gene id: 59894:ACER2
uniprot id: A0A803WCK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:LOC101809744
gene id: 59894:LOC101809744
uniprot id: A0A803VPC9
uniprot id: U3K9A4
names: Similarity
messages: Belongs to the intermediate filament family.

59894:MAP4K3
gene id: 59894:MAP4K3
uniprot id: A0A803WA67
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

59894:YKT6
gene id: 59894:YKT6
uniprot id: U3JBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

59894:NUP155
gene id: 59894:NUP155
uniprot id: A0A803VEN7
uniprot id: U3JH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

59894:PROX2
gene id: 59894:PROX2
uniprot id: U3JUY1
names: Subcellular Location Annotation
messages: Nucleus

59894:FZD9
gene id: 59894:FZD9
uniprot id: U3KIN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:LOC101813722
gene id: 59894:LOC101813722
uniprot id: U3JXR8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

59894:INHA
gene id: 59894:INHA
uniprot id: U3JNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

59894:VPS18
gene id: 59894:VPS18
uniprot id: U3JUE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

59894:TGFB3
gene id: 59894:TGFB3
uniprot id: U3JV88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

59894:SEC22A
gene id: 59894:SEC22A
uniprot id: U3KFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

59894:DDT
gene id: 59894:DDT
uniprot id: U3JXP7
names: Similarity
messages: Belongs to the MIF family.

59894:KNG1
gene id: 59894:KNG1
uniprot id: U3K0L9
names: Subcellular Location Annotation
messages: extracellular space

59894:SPATS2L
gene id: 59894:SPATS2L
uniprot id: A0A803V2K8
uniprot id: A0A803VLP4
names: Similarity
messages: Belongs to the SPATS2 family.

59894:DERL2
gene id: 59894:DERL2
uniprot id: U3K5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

59894:EZH1
gene id: 59894:EZH1
uniprot id: A0A803V4G2
names: Subcellular Location Annotation
messages: Nucleus

59894:AP2A2
gene id: 59894:AP2A2
uniprot id: A0A803V7A2
uniprot id: U3KBX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

59894:CAMSAP1
gene id: 59894:CAMSAP1
uniprot id: A0A803WFH2
uniprot id: U3JGF5
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

59894:ANPEP
gene id: 59894:ANPEP
uniprot id: U3K8Z9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

59894:GRIN2B
gene id: 59894:GRIN2B
uniprot id: U3KAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

59894:FOXN4
gene id: 59894:FOXN4
uniprot id: U3K294
names: Subcellular Location Annotation
messages: Nucleus

59894:PTPN12
gene id: 59894:PTPN12
uniprot id: A0A803WB94
uniprot id: U3K789
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

59894:LIPH
gene id: 59894:LIPH
uniprot id: U3KG45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

59894:ZRANB1
gene id: 59894:ZRANB1
uniprot id: U3JQI1
names: Similarity
messages: Belongs to the peptidase C64 family.

59894:MTG2
gene id: 59894:MTG2
uniprot id: U3K7Q1
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

59894:SLC13A2
gene id: 59894:SLC13A2
uniprot id: U3JVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

59894:GNAL
gene id: 59894:GNAL
uniprot id: A0A803W037
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

59894:PLIN2
gene id: 59894:PLIN2
uniprot id: U3JK86
names: Similarity
messages: Belongs to the perilipin family.

59894:MAP1LC3A
gene id: 59894:MAP1LC3A
uniprot id: U3KDI2
names: Similarity
messages: Belongs to the ATG8 family.

59894:CRYBB2
gene id: 59894:CRYBB2
uniprot id: A0A803V1Y3
uniprot id: U3K1U9
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

59894:C1R
gene id: 59894:C1R
uniprot id: A0A803VZF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:EHD3
gene id: 59894:EHD3
uniprot id: U3KAA3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

59894:HNF4G
gene id: 59894:HNF4G
uniprot id: A0A803V6U5
uniprot id: A0A803VUR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:LOC101810269
gene id: 59894:LOC101810269
uniprot id: U3KB61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

59894:SRC
gene id: 59894:SRC
uniprot id: U3JSL6
uniprot id: U3JSM0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:LOC101811833
gene id: 59894:LOC101811833
uniprot id: U3JK02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:LOC101815333
gene id: 59894:LOC101815333
uniprot id: A0A803VIC5
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

59894:POLG
gene id: 59894:POLG
uniprot id: U3K7F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-A family.
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

59894:MMGT1
gene id: 59894:MMGT1
uniprot id: U3JNY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

59894:AMPD1
gene id: 59894:AMPD1
uniprot id: A0A803W4L4
uniprot id: U3JLA7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

59894:AMPD2
gene id: 59894:AMPD2
uniprot id: U3JJU3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

59894:DNMT3B
gene id: 59894:DNMT3B
uniprot id: A0A803VCF9
uniprot id: A0A803VMF5
names: Subcellular Location Annotation
messages: Nucleus

59894:ITGB3
gene id: 59894:ITGB3
uniprot id: A0A803W9U8
uniprot id: U3K062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

59894:LOC101807812
gene id: 59894:LOC101807812
uniprot id: U3KKZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:LYPLAL1
gene id: 59894:LYPLAL1
uniprot id: U3KCI8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

59894:ZBED4
gene id: 59894:ZBED4
uniprot id: U3KLI7
names: Subcellular Location Annotation
messages: Nucleus

59894:PLPPR3
gene id: 59894:PLPPR3
uniprot id: U3KHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

59894:LOC101809283
gene id: 59894:LOC101809283
uniprot id: U3JC52
names: Similarity
messages: Belongs to the intermediate filament family.

59894:SPTLC3
gene id: 59894:SPTLC3
uniprot id: U3K8R5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

59894:LOC101805628
gene id: 59894:LOC101805628
uniprot id: U3JCA0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

59894:PIGP
gene id: 59894:PIGP
uniprot id: U3JRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

59894:AKAP1
gene id: 59894:AKAP1
uniprot id: U3JQW9
names: Subcellular Location Annotation
messages: Cytoplasm

59894:ND2
gene id: 59894:ND2
uniprot id: S0AU78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

59894:UNC50
gene id: 59894:UNC50
uniprot id: U3JMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

59894:LOC107603375
gene id: 59894:LOC107603375
uniprot id: A0A803W4T2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:LOC101806482
gene id: 59894:LOC101806482
uniprot id: A0A803VG22
names: Similarity
messages: Belongs to the CD225/Dispanin family.

59894:TACSTD2
gene id: 59894:TACSTD2
uniprot id: U3KL08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:GALT
gene id: 59894:GALT
uniprot id: U3K5D7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.

59894:APH1A
gene id: 59894:APH1A
uniprot id: U3JHL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

59894:NDUFV2
gene id: 59894:NDUFV2
uniprot id: U3JV48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

59894:SYNM
gene id: 59894:SYNM
uniprot id: U3K6W0
names: Similarity
messages: Belongs to the intermediate filament family.

59894:POP5
gene id: 59894:POP5
uniprot id: A0A803VBM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

59894:EMC2
gene id: 59894:EMC2
uniprot id: A0A803VJ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

59894:USP13
gene id: 59894:USP13
uniprot id: A0A803VS62
uniprot id: U3K0Z6
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:MAN1B1
gene id: 59894:MAN1B1
uniprot id: U3JQC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

59894:NPRL3
gene id: 59894:NPRL3
uniprot id: A0A803V4W6
uniprot id: A0A803W6J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

59894:ALDH1L2
gene id: 59894:ALDH1L2
uniprot id: U3KG77
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

59894:LOC101807521
gene id: 59894:LOC101807521
uniprot id: A0A803VID5
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

59894:PPM1F
gene id: 59894:PPM1F
uniprot id: U3JZR6
names: Similarity
messages: Belongs to the PP2C family.

59894:KAT6A
gene id: 59894:KAT6A
uniprot id: U3JV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

59894:ADRA1B
gene id: 59894:ADRA1B
uniprot id: U3K2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

59894:MCM4
gene id: 59894:MCM4
uniprot id: U3JTB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

59894:BMS1
gene id: 59894:BMS1
uniprot id: U3JWM7
names: Subcellular Location Annotation
messages: nucleolus

59894:NPFFR1
gene id: 59894:NPFFR1
uniprot id: U3KDS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

59894:LOC101817763
gene id: 59894:LOC101817763
uniprot id: A0A803W610
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:FOXO3
gene id: 59894:FOXO3
uniprot id: A0A803VC52
names: Subcellular Location Annotation
messages: Nucleus

59894:SATB1
gene id: 59894:SATB1
uniprot id: A0A803WAT4
uniprot id: U3K3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

59894:STK40
gene id: 59894:STK40
uniprot id: U3JDL8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

59894:GRM1
gene id: 59894:GRM1
uniprot id: U3KF58
uniprot id: U3KF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

59894:PPARGC1A
gene id: 59894:PPARGC1A
uniprot id: A0A803VFB1
names: Subcellular Location Annotation
messages: PML body

59894:LOC101808562
gene id: 59894:LOC101808562
uniprot id: A0A803V7G0
names: Similarity
messages: Belongs to the glutamine synthetase family.

59894:SFN
gene id: 59894:SFN
uniprot id: U3KIK8
names: Similarity
messages: Belongs to the 14-3-3 family.

59894:LOC101810295
gene id: 59894:LOC101810295
uniprot id: U3JIK4
names: Similarity
messages: Belongs to the serpin family.

59894:TCTEX1D4
gene id: 59894:TCTEX1D4
uniprot id: U3KI88
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

59894:USP33
gene id: 59894:USP33
uniprot id: U3JT64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

59894:CHEK1
gene id: 59894:CHEK1
uniprot id: U3JRB8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

59894:LOC101820249
gene id: 59894:LOC101820249
uniprot id: A0A803W2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM76 family.
messages: Belongs to the sestrin family.
messages: Cytoplasm

59894:LOC101810119
gene id: 59894:LOC101810119
uniprot id: U3JKB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:LOC101818934
gene id: 59894:LOC101818934
uniprot id: U3KI75
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:TTC21B
gene id: 59894:TTC21B
uniprot id: U3K152
names: Similarity
messages: Belongs to the TTC21 family.

59894:ST8SIA5
gene id: 59894:ST8SIA5
uniprot id: U3K2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:HSF4
gene id: 59894:HSF4
uniprot id: U3JYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

59894:RPL21
gene id: 59894:RPL21
uniprot id: A0A803VMB2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

59894:CD34
gene id: 59894:CD34
uniprot id: U3JCN4
names: Subcellular Location Annotation
messages: Membrane

59894:EIF2D
gene id: 59894:EIF2D
uniprot id: U3JCT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF2D family.
messages: Cytoplasm
messages: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.

59894:OXR1
gene id: 59894:OXR1
uniprot id: A0A803VTU1
uniprot id: A0A803VU84
uniprot id: U3JU84
names: Similarity
messages: Belongs to the OXR1 family.

59894:CNP
gene id: 59894:CNP
uniprot id: U3JD02
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: Melanosome
messages: Membrane

59894:HS3ST5
gene id: 59894:HS3ST5
uniprot id: U3K8V3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:MED22
gene id: 59894:MED22
uniprot id: A0A803V591
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

59894:LOC101814140
gene id: 59894:LOC101814140
uniprot id: A0A803VNQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:FSHR
gene id: 59894:FSHR
uniprot id: A0A803V4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

59894:SGCD
gene id: 59894:SGCD
uniprot id: U3K132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

59894:TMTC3
gene id: 59894:TMTC3
uniprot id: U3K7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

59894:RPS2
gene id: 59894:RPS2
uniprot id: U3JL79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Nucleus

59894:LPAR3
gene id: 59894:LPAR3
uniprot id: U3JUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:SS18
gene id: 59894:SS18
uniprot id: A0A803VZ89
uniprot id: U3JU68
names: Similarity
messages: Belongs to the SS18 family.

59894:NCBP3
gene id: 59894:NCBP3
uniprot id: U3JW44
names: Similarity
messages: Belongs to the NCBP3 family.

59894:KIF20A
gene id: 59894:KIF20A
uniprot id: U3K2C8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:TMEM184C
gene id: 59894:TMEM184C
uniprot id: A0A803VF23
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101808517
gene id: 59894:LOC101808517
uniprot id: U3JXL5
names: Similarity
messages: Belongs to the SELO family.

59894:SLC15A2
gene id: 59894:SLC15A2
uniprot id: U3KFQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

59894:RTCB
gene id: 59894:RTCB
uniprot id: U3KFW2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

59894:TEAD3
gene id: 59894:TEAD3
uniprot id: A0A803V810
uniprot id: A0A803VKR1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

59894:BRPF1
gene id: 59894:BRPF1
uniprot id: U3KEJ4
names: Subcellular Location Annotation
messages: Nucleus

59894:ACTR10
gene id: 59894:ACTR10
uniprot id: U3JLU8
names: Similarity
messages: Belongs to the actin family.

59894:ND4
gene id: 59894:ND4
uniprot id: S0ARW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

59894:LOC101813310
gene id: 59894:LOC101813310
uniprot id: A0A803VB08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

59894:TDP1
gene id: 59894:TDP1
uniprot id: A0A803V0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

59894:MFSD14A
gene id: 59894:MFSD14A
uniprot id: A0A803VPM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

59894:NECAP1
gene id: 59894:NECAP1
uniprot id: U3JXP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

59894:MAP3K8
gene id: 59894:MAP3K8
uniprot id: U3JXE0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

59894:GINS1
gene id: 59894:GINS1
uniprot id: A0A803W5N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

59894:LOC101814418
gene id: 59894:LOC101814418
uniprot id: A0A803V6S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

59894:LOC101820841
gene id: 59894:LOC101820841
uniprot id: A0A803WC00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

59894:MAPKAP1
gene id: 59894:MAPKAP1
uniprot id: U3JHP0
names: Similarity
messages: Belongs to the SIN1 family.

59894:LOC101818785
gene id: 59894:LOC101818785
uniprot id: U3KCP2
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

59894:LOC101819100
gene id: 59894:LOC101819100
uniprot id: A0A803VFW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:ALKBH8
gene id: 59894:ALKBH8
uniprot id: A0A803V7C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

59894:CCT5
gene id: 59894:CCT5
uniprot id: U3JZG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

59894:CALCA
gene id: 59894:CALCA
uniprot id: A0A803W094
names: Similarity
messages: Belongs to the calcitonin family.

59894:CHMP3
gene id: 59894:CHMP3
uniprot id: A0A803W000
names: Similarity
messages: Belongs to the SNF7 family.

59894:LOC101812227
gene id: 59894:LOC101812227
uniprot id: U3KKZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:ABLIM2
gene id: 59894:ABLIM2
uniprot id: A0A803VEK7
uniprot id: U3K4Y4
names: Subcellular Location Annotation
messages: Cytoplasm

59894:HDHD2
gene id: 59894:HDHD2
uniprot id: U3K2R3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

59894:DYX1C1
gene id: 59894:DYX1C1
uniprot id: U3KC26
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

59894:NSF
gene id: 59894:NSF
uniprot id: U3JYQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

59894:MED7
gene id: 59894:MED7
uniprot id: U3KIZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

59894:LOC101814732
gene id: 59894:LOC101814732
uniprot id: A0A803VKP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:RHAG
gene id: 59894:RHAG
uniprot id: U3KE41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

59894:PRKAR1A
gene id: 59894:PRKAR1A
uniprot id: U3JIJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

59894:OSBPL6
gene id: 59894:OSBPL6
uniprot id: U3JL89
names: Similarity
messages: Belongs to the OSBP family.

59894:MRPS10
gene id: 59894:MRPS10
uniprot id: A0A803VRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

59894:LOC101813502
gene id: 59894:LOC101813502
uniprot id: A0A803VEI8
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

59894:HPSE2
gene id: 59894:HPSE2
uniprot id: U3K0S5
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

59894:UBE2T
gene id: 59894:UBE2T
uniprot id: A0A803VSI6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

59894:NIPAL3
gene id: 59894:NIPAL3
uniprot id: A0A803W2U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

59894:FGFBP1
gene id: 59894:FGFBP1
uniprot id: U3KJW9
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

59894:KCNH8
gene id: 59894:KCNH8
uniprot id: U3K3P5
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

59894:FAM46A
gene id: 59894:FAM46A
uniprot id: U3JJ39
names: Similarity
messages: Belongs to the TENT family.

59894:CLP1
gene id: 59894:CLP1
uniprot id: U3K9D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

59894:PENK
gene id: 59894:PENK
uniprot id: U3K6V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

59894:PDE2A
gene id: 59894:PDE2A
uniprot id: U3JUQ9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:SLC45A4
gene id: 59894:SLC45A4
uniprot id: U3K2A8
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101813067
gene id: 59894:LOC101813067
uniprot id: U3KFF5
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:JAGN1
gene id: 59894:JAGN1
uniprot id: U3KEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:STARD8
gene id: 59894:STARD8
uniprot id: A0A803V5F2
uniprot id: U3JNM6
names: Subcellular Location Annotation
messages: Cytoplasm

59894:NPHS2
gene id: 59894:NPHS2
uniprot id: U3K0D9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

59894:PLAU
gene id: 59894:PLAU
uniprot id: U3JX40
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:SLC25A20
gene id: 59894:SLC25A20
uniprot id: U3KF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:NXPE3
gene id: 59894:NXPE3
uniprot id: A0A803V7A0
names: Similarity
messages: Belongs to the NXPE family.

59894:TMCC1
gene id: 59894:TMCC1
uniprot id: U3KGX2
names: Similarity
messages: Belongs to the TEX28 family.

59894:BCL9
gene id: 59894:BCL9
uniprot id: A0A803VU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

59894:ZDHHC3
gene id: 59894:ZDHHC3
uniprot id: A0A803WAJ2
uniprot id: U3JIV1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:GABRB2
gene id: 59894:GABRB2
uniprot id: A0A803VKZ4
uniprot id: U3KGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:SFR1
gene id: 59894:SFR1
uniprot id: U3K2E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

59894:CUL4B
gene id: 59894:CUL4B
uniprot id: U3JFP1
names: Similarity
messages: Belongs to the cullin family.

59894:LDAH
gene id: 59894:LDAH
uniprot id: A0A803VM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

59894:LOC101812721
gene id: 59894:LOC101812721
uniprot id: U3KH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

59894:HSPB1
gene id: 59894:HSPB1
uniprot id: U3K4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

59894:CPNE4
gene id: 59894:CPNE4
uniprot id: A0A803VMY3
uniprot id: U3KDC5
names: Similarity
messages: Belongs to the copine family.

59894:CDH9
gene id: 59894:CDH9
uniprot id: U3KE89
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:TBXAS1
gene id: 59894:TBXAS1
uniprot id: A0A803WBL9
uniprot id: U3K343
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:RAD21
gene id: 59894:RAD21
uniprot id: U3JHZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

59894:TNFAIP3
gene id: 59894:TNFAIP3
uniprot id: U3KEG7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:CPT2
gene id: 59894:CPT2
uniprot id: U3JT67
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

59894:SLC2A2
gene id: 59894:SLC2A2
uniprot id: U3K1M7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:C7H2orf76
gene id: 59894:C7H2orf76
uniprot id: A0A803WH07
names: Similarity
messages: Belongs to the UPF0538 family.

59894:GTDC1
gene id: 59894:GTDC1
uniprot id: A0A803V1Z1
uniprot id: U3KHE5
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

59894:KCNV1
gene id: 59894:KCNV1
uniprot id: U3JHV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

59894:LOC101808513
gene id: 59894:LOC101808513
uniprot id: U3KKZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:DUT
gene id: 59894:DUT
uniprot id: A0A803VM14
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

59894:MPP5
gene id: 59894:MPP5
uniprot id: U3JRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

59894:LAMP5
gene id: 59894:LAMP5
uniprot id: U3K971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Membrane

59894:TMED2
gene id: 59894:TMED2
uniprot id: U3K3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

59894:SGCE
gene id: 59894:SGCE
uniprot id: A0A803W572
names: Function
names: Similarity
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

59894:LOC101815283
gene id: 59894:LOC101815283
uniprot id: U3K2P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

59894:RPL8
gene id: 59894:RPL8
uniprot id: U3JFP0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

59894:LOC101812030
gene id: 59894:LOC101812030
uniprot id: U3JHE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

59894:A1CF
gene id: 59894:A1CF
uniprot id: U3KFF4
names: Subcellular Location Annotation
messages: Cytoplasm

59894:CAPN11
gene id: 59894:CAPN11
uniprot id: U3K9T7
names: Similarity
messages: Belongs to the peptidase C2 family.

59894:PSEN2
gene id: 59894:PSEN2
uniprot id: A0A803VRC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

59894:LAMC3
gene id: 59894:LAMC3
uniprot id: U3JFF7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

59894:PDE9A
gene id: 59894:PDE9A
uniprot id: A0A803V0T5
uniprot id: A0A803V194
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:LOC101817369
gene id: 59894:LOC101817369
uniprot id: A0A803VW13
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:DIP2C
gene id: 59894:DIP2C
uniprot id: A0A803VHS5
uniprot id: A0A803VN55
names: Similarity
messages: Belongs to the DIP2 family.

59894:ATP6V1C1
gene id: 59894:ATP6V1C1
uniprot id: U3JTR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

59894:RSPO3
gene id: 59894:RSPO3
uniprot id: U3KAF3
names: Similarity
messages: Belongs to the R-spondin family.

59894:PROKR1
gene id: 59894:PROKR1
uniprot id: A0A803VSW0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:DAPK2
gene id: 59894:DAPK2
uniprot id: U3K7Q3
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:TM2D1
gene id: 59894:TM2D1
uniprot id: A0A803VJQ6
names: Subcellular Location Annotation
messages: Membrane

59894:CTBP1
gene id: 59894:CTBP1
uniprot id: U3K636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

59894:ORMDL1
gene id: 59894:ORMDL1
uniprot id: U3JP82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

59894:IP6K1
gene id: 59894:IP6K1
uniprot id: A0A803VZ50
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

59894:LETM2
gene id: 59894:LETM2
uniprot id: U3JVZ8
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

59894:SLC35F4
gene id: 59894:SLC35F4
uniprot id: U3JLW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

59894:SLC20A1
gene id: 59894:SLC20A1
uniprot id: U3JBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

59894:TGM2
gene id: 59894:TGM2
uniprot id: U3JPG0
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

59894:CNDP2
gene id: 59894:CNDP2
uniprot id: U3JPY9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

59894:SLC16A1
gene id: 59894:SLC16A1
uniprot id: A0A803VY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

59894:CRH
gene id: 59894:CRH
uniprot id: U3JSC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

59894:EIF3E
gene id: 59894:EIF3E
uniprot id: U3JUB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

59894:MPG
gene id: 59894:MPG
uniprot id: U3JN92
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

59894:CLEC16A
gene id: 59894:CLEC16A
uniprot id: A0A803WC56
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

59894:SEPHS1
gene id: 59894:SEPHS1
uniprot id: U3JGT1
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

59894:LOC101815176
gene id: 59894:LOC101815176
uniprot id: U3JXV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

59894:SLC44A3
gene id: 59894:SLC44A3
uniprot id: U3JI48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

59894:B9D1
gene id: 59894:B9D1
uniprot id: A0A803VG73
names: Subcellular Location Annotation
messages: cilium basal body

59894:AK1
gene id: 59894:AK1
uniprot id: A0A803V5B7
uniprot id: U3JF18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

59894:ACAT2
gene id: 59894:ACAT2
uniprot id: U3KC85
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

59894:TOR1B
gene id: 59894:TOR1B
uniprot id: U3JFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

59894:ACYP2
gene id: 59894:ACYP2
uniprot id: A0A803V386
names: Similarity
messages: Belongs to the acylphosphatase family.

59894:SLC46A3
gene id: 59894:SLC46A3
uniprot id: U3K1J8
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101812006
gene id: 59894:LOC101812006
uniprot id: U3KL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

59894:TNPO1
gene id: 59894:TNPO1
uniprot id: A0A803WG81
names: Subcellular Location Annotation
messages: Cytoplasm

59894:TRADD
gene id: 59894:TRADD
uniprot id: A0A803V709
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

59894:ADTRP
gene id: 59894:ADTRP
uniprot id: A0A803VIK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

59894:SCGN
gene id: 59894:SCGN
uniprot id: U3JQ80
names: Subcellular Location Annotation
messages: Cytoplasm

59894:HMMR
gene id: 59894:HMMR
uniprot id: U3KGI8
names: Subcellular Location Annotation
messages: spindle

59894:ACSL5
gene id: 59894:ACSL5
uniprot id: U3JHV3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

59894:SF3A3
gene id: 59894:SF3A3
uniprot id: U3JE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3A3 family.
messages: Nucleus

59894:CASP6
gene id: 59894:CASP6
uniprot id: A0A803VZY0
names: Similarity
messages: Belongs to the peptidase C14A family.

59894:SLC10A2
gene id: 59894:SLC10A2
uniprot id: U3JNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

59894:PSMG2
gene id: 59894:PSMG2
uniprot id: U3JVE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

59894:LOC101807139
gene id: 59894:LOC101807139
uniprot id: U3KAX8
uniprot id: U3KAY6
names: Similarity
messages: Belongs to the CMC4 family.
messages: Belongs to the TCL1 family.

59894:ATP1B3
gene id: 59894:ATP1B3
uniprot id: U3JWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

59894:LOC101817609
gene id: 59894:LOC101817609
uniprot id: U3KH72
names: Subunit
messages: Monomer.

59894:ATP2A3
gene id: 59894:ATP2A3
uniprot id: A0A803W8U9
uniprot id: U3K5W4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

59894:CHRM2
gene id: 59894:CHRM2
uniprot id: A0A803VUS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

59894:CNRIP1
gene id: 59894:CNRIP1
uniprot id: A0A803VYL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

59894:SLC25A30
gene id: 59894:SLC25A30
uniprot id: A0A803VW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:MYOZ2
gene id: 59894:MYOZ2
uniprot id: U3JDS4
names: Similarity
messages: Belongs to the myozenin family.

59894:NCAPH
gene id: 59894:NCAPH
uniprot id: U3JC00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm

59894:SLC25A24
gene id: 59894:SLC25A24
uniprot id: U3JJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

59894:EPN3
gene id: 59894:EPN3
uniprot id: A0A803V0I1
uniprot id: A0A803V9G2
uniprot id: U3JF42
names: Similarity
messages: Belongs to the epsin family.

59894:LOC101817524
gene id: 59894:LOC101817524
uniprot id: U3KKE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

59894:CUL4A
gene id: 59894:CUL4A
uniprot id: U3JKQ4
names: Similarity
messages: Belongs to the cullin family.

59894:SPDYA
gene id: 59894:SPDYA
uniprot id: U3K9G7
names: Similarity
messages: Belongs to the Speedy/Ringo family.

59894:DMRT2
gene id: 59894:DMRT2
uniprot id: U3K735
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

59894:AKT1
gene id: 59894:AKT1
uniprot id: U3JJZ0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

59894:AQP1
gene id: 59894:AQP1
uniprot id: U3JDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

59894:DPH2
gene id: 59894:DPH2
uniprot id: U3JS13
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

59894:BAZ1B
gene id: 59894:BAZ1B
uniprot id: U3KGY4
names: Subcellular Location Annotation
messages: Nucleus

59894:UTP23
gene id: 59894:UTP23
uniprot id: U3JHY9
names: Subcellular Location Annotation
messages: nucleolus

59894:PROC
gene id: 59894:PROC
uniprot id: A0A803VJE1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:CASQ2
gene id: 59894:CASQ2
uniprot id: U3JUA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

59894:PRKD1
gene id: 59894:PRKD1
uniprot id: A0A803VW26
uniprot id: U3JT98
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

59894:SPDEF
gene id: 59894:SPDEF
uniprot id: A0A803VH15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:ART4
gene id: 59894:ART4
uniprot id: U3K9Y6
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

59894:LRRC42
gene id: 59894:LRRC42
uniprot id: U3KBW7
names: Similarity
messages: Belongs to the LRRC42 family.

59894:EZH2
gene id: 59894:EZH2
uniprot id: U3K6U9
names: Subcellular Location Annotation
messages: Nucleus

59894:BRINP1
gene id: 59894:BRINP1
uniprot id: A0A803VLR0
names: Similarity
messages: Belongs to the BRINP family.

59894:TENM4
gene id: 59894:TENM4
uniprot id: U3JYZ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:RPL5
gene id: 59894:RPL5
uniprot id: U3JG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

59894:ATP6V1G3
gene id: 59894:ATP6V1G3
uniprot id: A0A803VRZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

59894:LTBP2
gene id: 59894:LTBP2
uniprot id: U3JUW1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

59894:MGRN1
gene id: 59894:MGRN1
uniprot id: A0A803V9F2
uniprot id: A0A803WAY9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

59894:PDPR
gene id: 59894:PDPR
uniprot id: U3JY72
names: Similarity
messages: Belongs to the GcvT family.

59894:MED10
gene id: 59894:MED10
uniprot id: U3JXL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

59894:NRP2
gene id: 59894:NRP2
uniprot id: A0A803VLF5
uniprot id: U3JMJ3
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CIAPIN1
gene id: 59894:CIAPIN1
uniprot id: A0A803W9F5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

59894:RCAN1
gene id: 59894:RCAN1
uniprot id: A0A803VNE1
names: Similarity
messages: Belongs to the RCAN family.

59894:MKI67
gene id: 59894:MKI67
uniprot id: A0A803W367
names: Subcellular Location Annotation
messages: Nucleus

59894:SCAMP1
gene id: 59894:SCAMP1
uniprot id: U3K5W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

59894:CDKAL1
gene id: 59894:CDKAL1
uniprot id: U3KGF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

59894:SLC24A1
gene id: 59894:SLC24A1
uniprot id: U3K640
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

59894:SGPL1
gene id: 59894:SGPL1
uniprot id: U3JSG6
names: Similarity
messages: Belongs to the group II decarboxylase family.

59894:LOC101810494
gene id: 59894:LOC101810494
uniprot id: U3JS14
names: Similarity
messages: Belongs to the tumor necrosis factor family.

59894:USP20
gene id: 59894:USP20
uniprot id: U3JFE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

59894:CP
gene id: 59894:CP
uniprot id: A0A803VYE2
names: Similarity
messages: Belongs to the multicopper oxidase family.

59894:LOC101818738
gene id: 59894:LOC101818738
uniprot id: U3K4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

59894:LOC101812664
gene id: 59894:LOC101812664
uniprot id: U3JIC8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

59894:GRM5
gene id: 59894:GRM5
uniprot id: A0A803VBM7
uniprot id: A0A803VNZ3
uniprot id: U3JZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

59894:ABCG1
gene id: 59894:ABCG1
uniprot id: U3JH79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

59894:LOC101807456
gene id: 59894:LOC101807456
uniprot id: A0A803V2S4
uniprot id: A0A803W6C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

59894:TM4SF18
gene id: 59894:TM4SF18
uniprot id: U3JRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

59894:LOC101809627
gene id: 59894:LOC101809627
uniprot id: A0A803W991
uniprot id: U3JQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

59894:LOC101810757
gene id: 59894:LOC101810757
uniprot id: U3KKU9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane raft
messages: Secreted

59894:TAF9B
gene id: 59894:TAF9B
uniprot id: U3JNC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

59894:LOC101815304
gene id: 59894:LOC101815304
uniprot id: U3JHD3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

59894:LEFTY1
gene id: 59894:LEFTY1
uniprot id: U3KAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

59894:FAT1
gene id: 59894:FAT1
uniprot id: A0A803VYL1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:TSPAN14
gene id: 59894:TSPAN14
uniprot id: A0A803V3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:LOC101816142
gene id: 59894:LOC101816142
uniprot id: U3JHB9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:KCNJ1
gene id: 59894:KCNJ1
uniprot id: U3KKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

59894:HCRTR2
gene id: 59894:HCRTR2
uniprot id: U3JGK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:TRAPPC3
gene id: 59894:TRAPPC3
uniprot id: A0A803VQI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

59894:LOC101817916
gene id: 59894:LOC101817916
uniprot id: A0A803VCB5
names: Subcellular Location Annotation
messages: Membrane

59894:PHTF2
gene id: 59894:PHTF2
uniprot id: A0A803WEW3
uniprot id: U3K795
names: Subcellular Location Annotation
messages: Membrane

59894:OGDHL
gene id: 59894:OGDHL
uniprot id: A0A803VKA9
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

59894:LOC101806389
gene id: 59894:LOC101806389
uniprot id: U3JKQ8
names: Subcellular Location Annotation
messages: Membrane

59894:SH3BGRL3
gene id: 59894:SH3BGRL3
uniprot id: U3JC89
names: Similarity
messages: Belongs to the SH3BGR family.

59894:PRIM2
gene id: 59894:PRIM2
uniprot id: U3JG70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

59894:ADORA2B
gene id: 59894:ADORA2B
uniprot id: U3JUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

59894:BEST3
gene id: 59894:BEST3
uniprot id: U3K6K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

59894:NOX1
gene id: 59894:NOX1
uniprot id: U3JML0
names: Subcellular Location Annotation
messages: Membrane

59894:ANXA4
gene id: 59894:ANXA4
uniprot id: U3JBK7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

59894:HBEGF
gene id: 59894:HBEGF
uniprot id: U3K439
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:DRAXIN
gene id: 59894:DRAXIN
uniprot id: U3K681
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

59894:UGDH
gene id: 59894:UGDH
uniprot id: U3K3N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

59894:DES
gene id: 59894:DES
uniprot id: U3JNV6
names: Similarity
messages: Belongs to the intermediate filament family.

59894:ARPC1A
gene id: 59894:ARPC1A
uniprot id: U3KHB4
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

59894:ABCD3
gene id: 59894:ABCD3
uniprot id: A0A803WEG2
uniprot id: U3JI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

59894:LOC101814157
gene id: 59894:LOC101814157
uniprot id: U3KLL6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:KDM1B
gene id: 59894:KDM1B
uniprot id: U3KGC9
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

59894:CETP
gene id: 59894:CETP
uniprot id: A0A803VVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Secreted

59894:ID2
gene id: 59894:ID2
uniprot id: U3JVJ0
names: Subcellular Location Annotation
messages: Nucleus

59894:NEUROD6
gene id: 59894:NEUROD6
uniprot id: U3KI51
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101818227
gene id: 59894:LOC101818227
uniprot id: A0A803VC67
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

59894:TP53I11
gene id: 59894:TP53I11
uniprot id: U3KCR4
names: Subcellular Location Annotation
messages: Membrane

59894:POLR2D
gene id: 59894:POLR2D
uniprot id: A0A803WB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

59894:LOC101811650
gene id: 59894:LOC101811650
uniprot id: U3JZP6
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:IMPACT
gene id: 59894:IMPACT
uniprot id: U3JU81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

59894:VCAM1
gene id: 59894:VCAM1
uniprot id: A0A803VFL2
uniprot id: U3JIE0
names: Subcellular Location Annotation
messages: Cell membrane

59894:THBS1
gene id: 59894:THBS1
uniprot id: U3JS61
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:SNRPA1
gene id: 59894:SNRPA1
uniprot id: U3K6I7
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

59894:ADGRF5
gene id: 59894:ADGRF5
uniprot id: U3JFS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

59894:TRPV4
gene id: 59894:TRPV4
uniprot id: U3K251
names: Subcellular Location Annotation
messages: Membrane

59894:FAM83G
gene id: 59894:FAM83G
uniprot id: A0A803VRS3
names: Similarity
messages: Belongs to the FAM83 family.

59894:FN3K
gene id: 59894:FN3K
uniprot id: A0A803WDW8
names: Similarity
messages: Belongs to the fructosamine kinase family.

59894:CHGA
gene id: 59894:CHGA
uniprot id: U3JID6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

59894:LZTFL1
gene id: 59894:LZTFL1
uniprot id: A0A803W5Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

59894:HOXD12
gene id: 59894:HOXD12
uniprot id: U3JKE7
names: Subcellular Location Annotation
messages: Nucleus

59894:HDC
gene id: 59894:HDC
uniprot id: A0A803VH99
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

59894:LOC101809058
gene id: 59894:LOC101809058
uniprot id: A0A803VFI5
names: Similarity
messages: Belongs to the serpin family.

59894:EIF2B5
gene id: 59894:EIF2B5
uniprot id: U3JZR1
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

59894:PRKCH
gene id: 59894:PRKCH
uniprot id: U3JLA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

59894:SPHKAP
gene id: 59894:SPHKAP
uniprot id: A0A803W6T5
names: Similarity
messages: Belongs to the AKAP110 family.

59894:LOC101821726
gene id: 59894:LOC101821726
uniprot id: U3JUU4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

59894:CDC42SE2
gene id: 59894:CDC42SE2
uniprot id: A0A803VIK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

59894:RECQL
gene id: 59894:RECQL
uniprot id: U3JIZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

59894:KCNMA1
gene id: 59894:KCNMA1
uniprot id: A0A803VID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

59894:EPHB1
gene id: 59894:EPHB1
uniprot id: A0A803V6K9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

59894:HTR1D
gene id: 59894:HTR1D
uniprot id: U3KIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:TXNRD2
gene id: 59894:TXNRD2
uniprot id: U3K051
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

59894:MCM9
gene id: 59894:MCM9
uniprot id: A0A803WEE0
uniprot id: U3K9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

59894:FZD10
gene id: 59894:FZD10
uniprot id: U3KJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

59894:PEX12
gene id: 59894:PEX12
uniprot id: U3K530
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.
messages: Membrane
messages: Peroxisome membrane

59894:LOC101808610
gene id: 59894:LOC101808610
uniprot id: U3K881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

59894:NKAIN4
gene id: 59894:NKAIN4
uniprot id: A0A803V457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

59894:OSBPL1A
gene id: 59894:OSBPL1A
uniprot id: A0A803V6N1
uniprot id: U3JU89
names: Similarity
messages: Belongs to the OSBP family.

59894:GCG
gene id: 59894:GCG
uniprot id: U3JD74
names: Similarity
messages: Belongs to the glucagon family.

59894:PEX16
gene id: 59894:PEX16
uniprot id: A0A803WCE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

59894:NCL
gene id: 59894:NCL
uniprot id: U3JYT3
names: Subcellular Location Annotation
messages: nucleolus

59894:ATP6V0D2
gene id: 59894:ATP6V0D2
uniprot id: U3JQR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

59894:GNB3
gene id: 59894:GNB3
uniprot id: U3JQ32
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

59894:LOC101818177
gene id: 59894:LOC101818177
uniprot id: A0A803VKB9
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

59894:THPO
gene id: 59894:THPO
uniprot id: U3K0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

59894:TMEM231
gene id: 59894:TMEM231
uniprot id: A0A803WCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

59894:TMSB15B
gene id: 59894:TMSB15B
uniprot id: A0A803WFQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

59894:TGFBR2
gene id: 59894:TGFBR2
uniprot id: A0A803VXR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

59894:SGSM3
gene id: 59894:SGSM3
uniprot id: U3KCD1
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

59894:IPPK
gene id: 59894:IPPK
uniprot id: U3K336
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

59894:SLC11A1
gene id: 59894:SLC11A1
uniprot id: A0A803VQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

59894:SGSM1
gene id: 59894:SGSM1
uniprot id: U3K1V7
names: Similarity
messages: Belongs to the RUTBC family.

59894:TMEM206
gene id: 59894:TMEM206
uniprot id: U3KD60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

59894:LHX9
gene id: 59894:LHX9
uniprot id: U3JJD3
names: Subcellular Location Annotation
messages: Nucleus

59894:SYT16
gene id: 59894:SYT16
uniprot id: U3JL59
names: Similarity
messages: Belongs to the synaptotagmin family.

59894:DLGAP1
gene id: 59894:DLGAP1
uniprot id: A0A803W2Z5
names: Similarity
messages: Belongs to the SAPAP family.

59894:ZEB2
gene id: 59894:ZEB2
uniprot id: A0A803VDL1
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

59894:RELL1
gene id: 59894:RELL1
uniprot id: A0A803WCL0
names: Similarity
messages: Belongs to the RELT family.

59894:CCDC103
gene id: 59894:CCDC103
uniprot id: U3JYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

59894:KCNMB2
gene id: 59894:KCNMB2
uniprot id: A0A803V6B3
uniprot id: U3K165
names: Subcellular Location Annotation
messages: Membrane

59894:TPM1
gene id: 59894:TPM1
uniprot id: A0A803VWQ6
uniprot id: A0A803W6L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

59894:AIM1
gene id: 59894:AIM1
uniprot id: A0A803VAC7
uniprot id: A0A803VMI7
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

59894:TAGLN3
gene id: 59894:TAGLN3
uniprot id: U3JV09
names: Similarity
messages: Belongs to the calponin family.

59894:NELL2
gene id: 59894:NELL2
uniprot id: A0A803VT73
uniprot id: U3K6G6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:PPP3CB
gene id: 59894:PPP3CB
uniprot id: A0A803V7L5
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

59894:EIF5
gene id: 59894:EIF5
uniprot id: U3JJJ2
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

59894:CD151
gene id: 59894:CD151
uniprot id: U3K7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:CHL1
gene id: 59894:CHL1
uniprot id: A0A803VZB3
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

59894:LOC101819916
gene id: 59894:LOC101819916
uniprot id: U3K1N5
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

59894:TPD52
gene id: 59894:TPD52
uniprot id: A0A803W1G2
names: Similarity
messages: Belongs to the TPD52 family.

59894:MTMR6
gene id: 59894:MTMR6
uniprot id: U3K206
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

59894:SGCG
gene id: 59894:SGCG
uniprot id: A0A803W4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

59894:TMEM43
gene id: 59894:TMEM43
uniprot id: U3KDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

59894:TRAPPC13
gene id: 59894:TRAPPC13
uniprot id: A0A803WG12
uniprot id: U3K584
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

59894:MRPL19
gene id: 59894:MRPL19
uniprot id: U3JFX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

59894:LOC101811311
gene id: 59894:LOC101811311
uniprot id: U3KKS0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:TLR4
gene id: 59894:TLR4
uniprot id: U3JZ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

59894:OAZ2
gene id: 59894:OAZ2
uniprot id: U3K5E6
names: Similarity
messages: Belongs to the ODC antizyme family.

59894:GJA3
gene id: 59894:GJA3
uniprot id: U3KKC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:SLC6A20
gene id: 59894:SLC6A20
uniprot id: A0A803VIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:PMS1
gene id: 59894:PMS1
uniprot id: U3JP79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

59894:ERC2
gene id: 59894:ERC2
uniprot id: A0A803VBN2
names: Subcellular Location Annotation
messages: Cytoplasm

59894:ATP5H
gene id: 59894:ATP5H
uniprot id: U3JET3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

59894:ZDHHC9
gene id: 59894:ZDHHC9
uniprot id: U3KB32
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:MANEA
gene id: 59894:MANEA
uniprot id: A0A803W2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:LOC101810720
gene id: 59894:LOC101810720
uniprot id: U3KKZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:KCNK18
gene id: 59894:KCNK18
uniprot id: U3JHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

59894:TBP
gene id: 59894:TBP
uniprot id: A0A803VZX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

59894:NEK6
gene id: 59894:NEK6
uniprot id: U3JHC1
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:LOC101814041
gene id: 59894:LOC101814041
uniprot id: U3JZ95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

59894:LOC107604314
gene id: 59894:LOC107604314
uniprot id: U3KK43
names: Function
messages: The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Endogenous Gag proteins may have kept, lost or modified their original function during evolution.

59894:SLC31A1
gene id: 59894:SLC31A1
uniprot id: A0A803VH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

59894:FLOT2
gene id: 59894:FLOT2
uniprot id: U3JV22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

59894:LOC101809663
gene id: 59894:LOC101809663
uniprot id: A0A803VDW7
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:LOC101814266
gene id: 59894:LOC101814266
uniprot id: U3JR89
names: Similarity
messages: Belongs to the peptidase M14 family.

59894:SPATA6
gene id: 59894:SPATA6
uniprot id: U3JRW3
names: Similarity
messages: Belongs to the SPATA6 family.

59894:ANAPC13
gene id: 59894:ANAPC13
uniprot id: A0A803VDJ4
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

59894:PLPPR4
gene id: 59894:PLPPR4
uniprot id: A0A803VNJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

59894:FAM173B
gene id: 59894:FAM173B
uniprot id: U3JZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

59894:DYM
gene id: 59894:DYM
uniprot id: A0A803VAX3
uniprot id: A0A803W3E8
uniprot id: U3K2T9
names: Similarity
messages: Belongs to the dymeclin family.

59894:ITIH2
gene id: 59894:ITIH2
uniprot id: U3JGK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

59894:SHQ1
gene id: 59894:SHQ1
uniprot id: U3KG57
names: Similarity
messages: Belongs to the SHQ1 family.

59894:KATNA1
gene id: 59894:KATNA1
uniprot id: U3KCD9
uniprot id: U3KCE0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

59894:CLDN1
gene id: 59894:CLDN1
uniprot id: A0A803VS81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:SLC6A8
gene id: 59894:SLC6A8
uniprot id: U3KF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:ABCA1
gene id: 59894:ABCA1
uniprot id: A0A803VYI5
names: Subcellular Location Annotation
messages: Membrane

59894:ELAVL2
gene id: 59894:ELAVL2
uniprot id: A0A803VLA9
uniprot id: A0A803WAH9
names: Similarity
messages: Belongs to the RRM elav family.

59894:LEO1
gene id: 59894:LEO1
uniprot id: U3KBG3
names: Similarity
messages: Belongs to the LEO1 family.

59894:ANAPC15
gene id: 59894:ANAPC15
uniprot id: U3JUV0
names: Similarity
messages: Belongs to the APC15 family.

59894:LOC101808544
gene id: 59894:LOC101808544
uniprot id: U3KL31
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:CD164L2
gene id: 59894:CD164L2
uniprot id: A0A803VW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

59894:VIPR1
gene id: 59894:VIPR1
uniprot id: A0A803VX39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

59894:ELOVL4
gene id: 59894:ELOVL4
uniprot id: A0A803VZA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

59894:FGF22
gene id: 59894:FGF22
uniprot id: U3KHL1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

59894:VAMP7
gene id: 59894:VAMP7
uniprot id: U3KAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

59894:TMEM168
gene id: 59894:TMEM168
uniprot id: A0A803W5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane
messages: Nucleus membrane

59894:MEGF11
gene id: 59894:MEGF11
uniprot id: U3K625
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:C5H14orf159
gene id: 59894:C5H14orf159
uniprot id: A0A803V2Q3
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

59894:LOC101806598
gene id: 59894:LOC101806598
uniprot id: A0A803VPF1
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.

59894:E2F7
gene id: 59894:E2F7
uniprot id: U3K779
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

59894:MRPL14
gene id: 59894:MRPL14
uniprot id: A0A803W0M4
uniprot id: U3K9V9
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

59894:KDM4C
gene id: 59894:KDM4C
uniprot id: U3K7V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

59894:LPCAT2
gene id: 59894:LPCAT2
uniprot id: U3JZN1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

59894:PDK3
gene id: 59894:PDK3
uniprot id: U3JND3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

59894:NSUN6
gene id: 59894:NSUN6
uniprot id: U3JY68
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

59894:CNTNAP5
gene id: 59894:CNTNAP5
uniprot id: U3KFG3
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:NPLOC4
gene id: 59894:NPLOC4
uniprot id: U3KDX6
names: Similarity
messages: Belongs to the NPL4 family.

59894:MRPS9
gene id: 59894:MRPS9
uniprot id: U3JM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS9 family.
messages: Nucleus

59894:METTL16
gene id: 59894:METTL16
uniprot id: U3JRR9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

59894:LOC101813135
gene id: 59894:LOC101813135
uniprot id: A0A803VP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

59894:ACTN2
gene id: 59894:ACTN2
uniprot id: U3KG99
names: Similarity
messages: Belongs to the alpha-actinin family.

59894:LOC101809825
gene id: 59894:LOC101809825
uniprot id: U3JC50
names: Similarity
messages: Belongs to the intermediate filament family.

59894:GDPD5
gene id: 59894:GDPD5
uniprot id: A0A803VI36
uniprot id: A0A803VYQ0
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

59894:PLCD4
gene id: 59894:PLCD4
uniprot id: U3JNB4
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

59894:PPP1R14D
gene id: 59894:PPP1R14D
uniprot id: A0A803W800
names: Similarity
messages: Belongs to the PP1 inhibitor family.

59894:CACNG5
gene id: 59894:CACNG5
uniprot id: U3JIA7
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

59894:CSGALNACT1
gene id: 59894:CSGALNACT1
uniprot id: U3JVN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

59894:FAM162A
gene id: 59894:FAM162A
uniprot id: U3JQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

59894:DFNA5
gene id: 59894:DFNA5
uniprot id: U3K4L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

59894:ROCK1
gene id: 59894:ROCK1
uniprot id: U3JUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Membrane

59894:RXRG
gene id: 59894:RXRG
uniprot id: U3JZQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

59894:ITGB2
gene id: 59894:ITGB2
uniprot id: U3KFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

59894:RNF34
gene id: 59894:RNF34
uniprot id: U3K3E3
names: Subcellular Location Annotation
messages: Cell membrane

59894:ELOVL7
gene id: 59894:ELOVL7
uniprot id: U3K915
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:S1PR3
gene id: 59894:S1PR3
uniprot id: U3KJ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LOC101819765
gene id: 59894:LOC101819765
uniprot id: A0A803W5W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

59894:LIN9
gene id: 59894:LIN9
uniprot id: A0A803WFC3
names: Similarity
messages: Belongs to the lin-9 family.

59894:ZC3H12A
gene id: 59894:ZC3H12A
uniprot id: U3JDR7
names: Similarity
messages: Belongs to the ZC3H12 family.

59894:LCORL
gene id: 59894:LCORL
uniprot id: U3K3L7
names: Subcellular Location Annotation
messages: Nucleus

59894:SUGCT
gene id: 59894:SUGCT
uniprot id: A0A803VLZ0
names: Similarity
messages: Belongs to the CoA-transferase III family.

59894:PIK3R2
gene id: 59894:PIK3R2
uniprot id: U3KHD9
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

59894:GATC
gene id: 59894:GATC
uniprot id: A0A803VE07
uniprot id: A0A803VRI0
uniprot id: A0A803W3U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

59894:LOC101813301
gene id: 59894:LOC101813301
uniprot id: U3KHS5
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

59894:LOC101812891
gene id: 59894:LOC101812891
uniprot id: U3JK74
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:LOC101818184
gene id: 59894:LOC101818184
uniprot id: U3KKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

59894:LOC101819144
gene id: 59894:LOC101819144
uniprot id: U3KF04
names: Similarity
messages: Belongs to the serpin family.

59894:LOC101808108
gene id: 59894:LOC101808108
uniprot id: U3JHQ0
names: Similarity
messages: Belongs to the avidin/streptavidin family.

59894:AKR1A1
gene id: 59894:AKR1A1
uniprot id: U3K4S3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

59894:BCLAF1
gene id: 59894:BCLAF1
uniprot id: A0A803VQK4
uniprot id: U3KEN9
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

59894:RAB11FIP4
gene id: 59894:RAB11FIP4
uniprot id: U3JHW9
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

59894:PSME4
gene id: 59894:PSME4
uniprot id: U3KA06
names: Similarity
messages: Belongs to the BLM10 family.

59894:SLC26A1
gene id: 59894:SLC26A1
uniprot id: A0A803V7T3
uniprot id: A0A803VCU5
uniprot id: U3JRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent sulfate anion transporter. Can transport other anions including bicarbonate, thiosulfate and oxalate.

59894:EEF2
gene id: 59894:EEF2
uniprot id: U3JDP2
names: Subcellular Location Annotation
messages: Nucleus

59894:CNR2
gene id: 59894:CNR2
uniprot id: U3KIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:AMIGO2
gene id: 59894:AMIGO2
uniprot id: U3KKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

59894:SLC23A2
gene id: 59894:SLC23A2
uniprot id: U3JBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

59894:LOC101807360
gene id: 59894:LOC101807360
uniprot id: A0A803W1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

59894:COG7
gene id: 59894:COG7
uniprot id: U3KI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:IBSP
gene id: 59894:IBSP
uniprot id: U3JR86
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

59894:CACNB2
gene id: 59894:CACNB2
uniprot id: A0A803V6M7
uniprot id: A0A803VD88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: sarcolemma

59894:HDLBP
gene id: 59894:HDLBP
uniprot id: U3JLC2
names: Subcellular Location Annotation
messages: Cytoplasm

59894:SEC16A
gene id: 59894:SEC16A
uniprot id: A0A803WGF8
uniprot id: U3JGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

59894:GSX1
gene id: 59894:GSX1
uniprot id: A0A803VF76
names: Subcellular Location Annotation
messages: Nucleus

59894:HTR1E
gene id: 59894:HTR1E
uniprot id: U3KJX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:HMBOX1
gene id: 59894:HMBOX1
uniprot id: A0A803V9X8
names: Subcellular Location Annotation
messages: Nucleus

59894:PRMT7
gene id: 59894:PRMT7
uniprot id: U3JZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

59894:MTO1
gene id: 59894:MTO1
uniprot id: U3JX70
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

59894:PPP1R21
gene id: 59894:PPP1R21
uniprot id: U3K987
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

59894:CFLAR
gene id: 59894:CFLAR
uniprot id: U3JNF5
names: Similarity
messages: Belongs to the peptidase C14A family.

59894:LYZ
gene id: 59894:LYZ
uniprot id: A0A803WC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Secreted

59894:WNT2B
gene id: 59894:WNT2B
uniprot id: U3JD43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:NKX6-3
gene id: 59894:NKX6-3
uniprot id: U3JVA1
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101809792
gene id: 59894:LOC101809792
uniprot id: A0A803V348
names: Similarity
messages: Belongs to the DeSI family.

59894:MTFP1
gene id: 59894:MTFP1
uniprot id: U3JWR1
names: Similarity
messages: Belongs to the MTFP1 family.

59894:CCNG1
gene id: 59894:CCNG1
uniprot id: U3KGI4
names: Similarity
messages: Belongs to the cyclin family.

59894:FAM73A
gene id: 59894:FAM73A
uniprot id: A0A803VCA7
names: Similarity
messages: Belongs to the mitoguardin family.

59894:BAMBI
gene id: 59894:BAMBI
uniprot id: U3JXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

59894:PYCR1
gene id: 59894:PYCR1
uniprot id: U3KBI1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

59894:INS
gene id: 59894:INS
uniprot id: U3KAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

59894:SLC26A5
gene id: 59894:SLC26A5
uniprot id: U3K734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

59894:SLC5A7
gene id: 59894:SLC5A7
uniprot id: U3JLS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

59894:FOXO6
gene id: 59894:FOXO6
uniprot id: A0A803VAP2
names: Subcellular Location Annotation
messages: Nucleus

59894:GUF1
gene id: 59894:GUF1
uniprot id: A0A803VF01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

59894:ESRRG
gene id: 59894:ESRRG
uniprot id: A0A803VZ46
uniprot id: A0A803W1W7
uniprot id: A0A803WC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

59894:CHST15
gene id: 59894:CHST15
uniprot id: U3JQ87
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:KIF4A
gene id: 59894:KIF4A
uniprot id: A0A803W5C2
uniprot id: U3JNC6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:NUP93
gene id: 59894:NUP93
uniprot id: U3JYH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

59894:RFC5
gene id: 59894:RFC5
uniprot id: A0A803VKK7
names: Similarity
messages: Belongs to the activator 1 small subunits family.

59894:MAB21L3
gene id: 59894:MAB21L3
uniprot id: U3JUC1
names: Similarity
messages: Belongs to the mab-21 family.

59894:MDM2
gene id: 59894:MDM2
uniprot id: U3K6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

59894:LOC101820032
gene id: 59894:LOC101820032
uniprot id: U3KIJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

59894:SLC39A10
gene id: 59894:SLC39A10
uniprot id: U3JP03
names: Subcellular Location Annotation
messages: Membrane

59894:PDE10A
gene id: 59894:PDE10A
uniprot id: U3KCJ2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:CLUAP1
gene id: 59894:CLUAP1
uniprot id: A0A803W514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

59894:TNFAIP1
gene id: 59894:TNFAIP1
uniprot id: U3JQC7
names: Similarity
messages: Belongs to the BACURD family.

59894:ZNF503
gene id: 59894:ZNF503
uniprot id: U3JWT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

59894:MTMR8
gene id: 59894:MTMR8
uniprot id: A0A803VLJ0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

59894:RND3
gene id: 59894:RND3
uniprot id: U3KHG7
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

59894:ARL2BP
gene id: 59894:ARL2BP
uniprot id: U3JX12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

59894:CRY1
gene id: 59894:CRY1
uniprot id: U3KG30
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

59894:CRYBA2
gene id: 59894:CRYBA2
uniprot id: U3JNI8
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

59894:TUBGCP5
gene id: 59894:TUBGCP5
uniprot id: A0A803VYR5
uniprot id: U3JNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

59894:COL4A1
gene id: 59894:COL4A1
uniprot id: U3K7K7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

59894:VANGL1
gene id: 59894:VANGL1
uniprot id: U3JUA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

59894:RTFDC1
gene id: 59894:RTFDC1
uniprot id: U3K8K4
names: Similarity
messages: Belongs to the rtf2 family.

59894:CKS1B
gene id: 59894:CKS1B
uniprot id: A0A803VJI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

59894:FGF10
gene id: 59894:FGF10
uniprot id: U3K9I8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

59894:ATF2
gene id: 59894:ATF2
uniprot id: A0A803VC97
uniprot id: U3JKA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a dimer and can form a homodimer in the absence of DNA.
messages: Nucleus
messages: Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3').

59894:EEF1AKMT1
gene id: 59894:EEF1AKMT1
uniprot id: U3K265
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

59894:CLCN2
gene id: 59894:CLCN2
uniprot id: A0A803WAA2
uniprot id: U3K0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

59894:LOC101811124
gene id: 59894:LOC101811124
uniprot id: A0A803V4S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:C18H17orf62
gene id: 59894:C18H17orf62
uniprot id: A0A803WG09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:BPNT1
gene id: 59894:BPNT1
uniprot id: A0A803VN49
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

59894:MMP9
gene id: 59894:MMP9
uniprot id: A0A803WDU2
uniprot id: U3JQ15
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

59894:LOC101811258
gene id: 59894:LOC101811258
uniprot id: U3JWV6
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

59894:MTMR9
gene id: 59894:MTMR9
uniprot id: U3JIU7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

59894:MYOG
gene id: 59894:MYOG
uniprot id: A0A803V2D9
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101820808
gene id: 59894:LOC101820808
uniprot id: U3KA14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

59894:ZDHHC6
gene id: 59894:ZDHHC6
uniprot id: U3JHU8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:CCNF
gene id: 59894:CCNF
uniprot id: A0A803VJD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: Nucleus
messages: centriole
messages: perinuclear region

59894:LOC101810038
gene id: 59894:LOC101810038
uniprot id: U3K1U7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:VDAC1
gene id: 59894:VDAC1
uniprot id: U3JZN8
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

59894:DHCR7
gene id: 59894:DHCR7
uniprot id: A0A803VJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

59894:DEGS1
gene id: 59894:DEGS1
uniprot id: A0A803VBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane

59894:SEPT3
gene id: 59894:SEPT3
uniprot id: U3KB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

59894:OSBP
gene id: 59894:OSBP
uniprot id: U3KCE6
names: Similarity
messages: Belongs to the OSBP family.

59894:CSRNP1
gene id: 59894:CSRNP1
uniprot id: U3JW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

59894:STRN3
gene id: 59894:STRN3
uniprot id: A0A803V724
uniprot id: A0A803VXA1
uniprot id: A0A803W082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

59894:PHC1
gene id: 59894:PHC1
uniprot id: U3JY21
names: Subcellular Location Annotation
messages: Nucleus

59894:ING5
gene id: 59894:ING5
uniprot id: A0A803V9L3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

59894:RPP30
gene id: 59894:RPP30
uniprot id: U3JZ38
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

59894:OPN3
gene id: 59894:OPN3
uniprot id: A0A803VZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

59894:FAM53B
gene id: 59894:FAM53B
uniprot id: A0A803VM26
names: Similarity
messages: Belongs to the FAM53 family.

59894:RNFT1
gene id: 59894:RNFT1
uniprot id: A0A803VEG7
names: Subcellular Location Annotation
messages: Membrane

59894:PNRC1
gene id: 59894:PNRC1
uniprot id: U3JJY5
names: Subcellular Location Annotation
messages: Nucleus

59894:LRWD1
gene id: 59894:LRWD1
uniprot id: U3K4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

59894:GSTK1
gene id: 59894:GSTK1
uniprot id: A0A803V7L8
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

59894:ADCK3
gene id: 59894:ADCK3
uniprot id: A0A803WDB6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

59894:CAMK2A
gene id: 59894:CAMK2A
uniprot id: A0A803VCH0
uniprot id: U3JZX5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

59894:FAM13B
gene id: 59894:FAM13B
uniprot id: A0A803VFE9
uniprot id: A0A803W6K7
uniprot id: U3JYV2
names: Similarity
messages: Belongs to the FAM13 family.

59894:F5
gene id: 59894:F5
uniprot id: U3JTG7
names: Similarity
messages: Belongs to the multicopper oxidase family.

59894:TOP1MT
gene id: 59894:TOP1MT
uniprot id: U3K4M2
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

59894:GPATCH11
gene id: 59894:GPATCH11
uniprot id: A0A803VNN8
names: Similarity
messages: Belongs to the GPATCH11 family.

59894:PARVG
gene id: 59894:PARVG
uniprot id: U3JVU8
names: Similarity
messages: Belongs to the parvin family.

59894:TRPM7
gene id: 59894:TRPM7
uniprot id: U3KA58
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

59894:LOC101819471
gene id: 59894:LOC101819471
uniprot id: A0A803W310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:ISL1
gene id: 59894:ISL1
uniprot id: U3K9T9
names: Subcellular Location Annotation
messages: Nucleus

59894:TBK1
gene id: 59894:TBK1
uniprot id: U3K5R8
names: Subcellular Location Annotation
messages: Cytoplasm

59894:DSEL
gene id: 59894:DSEL
uniprot id: U3KJJ8
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

59894:MAN2C1
gene id: 59894:MAN2C1
uniprot id: U3K8B4
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

59894:WARS2
gene id: 59894:WARS2
uniprot id: A0A803W5W2
uniprot id: U3JR28
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

59894:ZFHX4
gene id: 59894:ZFHX4
uniprot id: A0A803VYC2
names: Subcellular Location Annotation
messages: Nucleus

59894:GRIN2A
gene id: 59894:GRIN2A
uniprot id: U3JN01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

59894:LOC101808210
gene id: 59894:LOC101808210
uniprot id: A0A803VD77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

59894:CHFR
gene id: 59894:CHFR
uniprot id: U3K0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

59894:NR4A3
gene id: 59894:NR4A3
uniprot id: U3JQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:POLR3A
gene id: 59894:POLR3A
uniprot id: U3JWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

59894:MTMR4
gene id: 59894:MTMR4
uniprot id: U3KH59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

59894:TMEM192
gene id: 59894:TMEM192
uniprot id: U3K9G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

59894:ATG16L1
gene id: 59894:ATG16L1
uniprot id: A0A803W1P7
uniprot id: U3KGG1
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

59894:NIF3L1
gene id: 59894:NIF3L1
uniprot id: A0A803VTK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

59894:ME1
gene id: 59894:ME1
uniprot id: U3JJ88
uniprot id: U3JJ92
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

59894:ADRA2A
gene id: 59894:ADRA2A
uniprot id: U3KKZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:SDR16C5
gene id: 59894:SDR16C5
uniprot id: U3K6U3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:HTR2A
gene id: 59894:HTR2A
uniprot id: U3K0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

59894:GALNS
gene id: 59894:GALNS
uniprot id: A0A803VAP0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Homodimer.
messages: Lysosome

59894:SLC18A2
gene id: 59894:SLC18A2
uniprot id: U3JHN5
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101819307
gene id: 59894:LOC101819307
uniprot id: U3JLW1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

59894:SLC7A9
gene id: 59894:SLC7A9
uniprot id: U3JBY8
names: Subcellular Location Annotation
messages: Membrane

59894:MEIS2
gene id: 59894:MEIS2
uniprot id: U3JSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

59894:GRK5
gene id: 59894:GRK5
uniprot id: U3JHM0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

59894:RPS6KA2
gene id: 59894:RPS6KA2
uniprot id: A0A803W3D0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

59894:RPS15A
gene id: 59894:RPS15A
uniprot id: U3KI09
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

59894:DDC
gene id: 59894:DDC
uniprot id: U3JYJ5
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

59894:LYRM2
gene id: 59894:LYRM2
uniprot id: A0A803V3L8
names: Similarity
messages: Belongs to the complex I LYR family.

59894:ARPP19
gene id: 59894:ARPP19
uniprot id: U3KBM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

59894:PEMT
gene id: 59894:PEMT
uniprot id: U3KH69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

59894:TFB1M
gene id: 59894:TFB1M
uniprot id: A0A803V9I3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

59894:LOC101815035
gene id: 59894:LOC101815035
uniprot id: A0A803WGL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

59894:TTC36
gene id: 59894:TTC36
uniprot id: U3K5S4
names: Similarity
messages: Belongs to the TTC36 family.

59894:IKBKAP
gene id: 59894:IKBKAP
uniprot id: U3JES9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

59894:DSE
gene id: 59894:DSE
uniprot id: U3K8X7
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

59894:ACSL4
gene id: 59894:ACSL4
uniprot id: U3JBM6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

59894:ST8SIA2
gene id: 59894:ST8SIA2
uniprot id: U3K720
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:PARVA
gene id: 59894:PARVA
uniprot id: U3K7T1
names: Similarity
messages: Belongs to the parvin family.

59894:CHPF
gene id: 59894:CHPF
uniprot id: U3JNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

59894:FLNB
gene id: 59894:FLNB
uniprot id: U3K0X6
names: Similarity
messages: Belongs to the filamin family.

59894:RAB3IL1
gene id: 59894:RAB3IL1
uniprot id: A0A803W750
uniprot id: U3JPC4
names: Similarity
messages: Belongs to the SEC2 family.

59894:IGF1R
gene id: 59894:IGF1R
uniprot id: U3K6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

59894:SLC41A3
gene id: 59894:SLC41A3
uniprot id: A0A803VAU5
uniprot id: U3JHA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

59894:TSG101
gene id: 59894:TSG101
uniprot id: U3K9H6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

59894:CNTN1
gene id: 59894:CNTN1
uniprot id: U3K6Y1
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

59894:LOC101818836
gene id: 59894:LOC101818836
uniprot id: U3KF02
names: Similarity
messages: Belongs to the serpin family.

59894:LOC101817188
gene id: 59894:LOC101817188
uniprot id: A0A803VII0
names: Similarity
messages: Belongs to the Luc7 family.

59894:CLCN1
gene id: 59894:CLCN1
uniprot id: U3JPJ8
names: Subcellular Location Annotation
messages: Membrane

59894:TINAG
gene id: 59894:TINAG
uniprot id: U3JGL1
names: Similarity
messages: Belongs to the peptidase C1 family.

59894:RFTN2
gene id: 59894:RFTN2
uniprot id: U3JNT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

59894:KIF18A
gene id: 59894:KIF18A
uniprot id: U3KCP5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:GRIA3
gene id: 59894:GRIA3
uniprot id: A0A803VL73
uniprot id: A0A803WED9
uniprot id: U3JFN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

59894:STX19
gene id: 59894:STX19
uniprot id: U3KK39
names: Similarity
messages: Belongs to the syntaxin family.

59894:PKD2L1
gene id: 59894:PKD2L1
uniprot id: U3JY36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Cell membrane
messages: Membrane
messages: cilium membrane

59894:TSPAN4
gene id: 59894:TSPAN4
uniprot id: A0A803W7K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:AP1S3
gene id: 59894:AP1S3
uniprot id: A0A803VWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

59894:FBXO32
gene id: 59894:FBXO32
uniprot id: U3JIG4
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101816351
gene id: 59894:LOC101816351
uniprot id: U3KD10
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:NDST2
gene id: 59894:NDST2
uniprot id: U3JX44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

59894:MTERF2
gene id: 59894:MTERF2
uniprot id: U3KLE5
names: Similarity
messages: Belongs to the mTERF family.

59894:MYF6
gene id: 59894:MYF6
uniprot id: U3K7F1
names: Subcellular Location Annotation
messages: Nucleus

59894:SMC6
gene id: 59894:SMC6
uniprot id: U3JGJ5
names: Subcellular Location Annotation
messages: Chromosome

59894:SCG5
gene id: 59894:SCG5
uniprot id: A0A803V4L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

59894:B4GALT4
gene id: 59894:B4GALT4
uniprot id: U3JU76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

59894:NKX2-5
gene id: 59894:NKX2-5
uniprot id: U3K2D8
names: Subcellular Location Annotation
messages: Nucleus

59894:POLR2H
gene id: 59894:POLR2H
uniprot id: U3K0G7
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

59894:LOC101819122
gene id: 59894:LOC101819122
uniprot id: A0A803WDC5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

59894:SYT1
gene id: 59894:SYT1
uniprot id: U3K7D1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

59894:CTNNB1
gene id: 59894:CTNNB1
uniprot id: A0A803V4M6
uniprot id: U3KCN8
names: Similarity
messages: Belongs to the beta-catenin family.

59894:AVL9
gene id: 59894:AVL9
uniprot id: U3JJ20
names: Subcellular Location Annotation
messages: Recycling endosome

59894:SVEP1
gene id: 59894:SVEP1
uniprot id: U3JBS0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:LOC101805674
gene id: 59894:LOC101805674
uniprot id: U3JTE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

59894:TUBAL3
gene id: 59894:TUBAL3
uniprot id: A0A803VCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

59894:GPX8
gene id: 59894:GPX8
uniprot id: A0A803VB18
names: Similarity
messages: Belongs to the glutathione peroxidase family.

59894:MVK
gene id: 59894:MVK
uniprot id: U3K254
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm
messages: Nucleus

59894:PPP1R15B
gene id: 59894:PPP1R15B
uniprot id: U3JCE0
names: Similarity
messages: Belongs to the PPP1R15 family.

59894:SAMD4A
gene id: 59894:SAMD4A
uniprot id: A0A803UZX7
uniprot id: A0A803VUP1
uniprot id: U3JMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

59894:CORO2A
gene id: 59894:CORO2A
uniprot id: A0A803V8Y3
names: Similarity
messages: Belongs to the WD repeat coronin family.

59894:LOC101820195
gene id: 59894:LOC101820195
uniprot id: U3JFJ3
names: Similarity
messages: Belongs to the CD200R family.

59894:MED8
gene id: 59894:MED8
uniprot id: U3JSP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

59894:MAGT1
gene id: 59894:MAGT1
uniprot id: A0A803VZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:GTF2H1
gene id: 59894:GTF2H1
uniprot id: U3K9D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

59894:MTX2
gene id: 59894:MTX2
uniprot id: U3JKN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

59894:LOC101812766
gene id: 59894:LOC101812766
uniprot id: U3JXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

59894:PRDM1
gene id: 59894:PRDM1
uniprot id: A0A803WFW5
uniprot id: U3KAS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

59894:PGAP2
gene id: 59894:PGAP2
uniprot id: U3K6J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

59894:SLC39A6
gene id: 59894:SLC39A6
uniprot id: U3JR77
names: Subcellular Location Annotation
messages: Membrane

59894:TENM3
gene id: 59894:TENM3
uniprot id: U3KAS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:GDF5
gene id: 59894:GDF5
uniprot id: U3KDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

59894:CKS2
gene id: 59894:CKS2
uniprot id: U3KD79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

59894:TBX5
gene id: 59894:TBX5
uniprot id: U3JZB8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

59894:SPO11
gene id: 59894:SPO11
uniprot id: U3K8E1
names: Similarity
messages: Belongs to the TOP6A family.

59894:ST3GAL6
gene id: 59894:ST3GAL6
uniprot id: A0A803V0K5
uniprot id: A0A803VTE2
uniprot id: A0A803W4L2
uniprot id: U3JTB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:TUBGCP4
gene id: 59894:TUBGCP4
uniprot id: A0A803WC93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

59894:PDE5A
gene id: 59894:PDE5A
uniprot id: U3JDP9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:UBE2G1
gene id: 59894:UBE2G1
uniprot id: A0A803VGU7
uniprot id: U3JXI5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

59894:PDS5A
gene id: 59894:PDS5A
uniprot id: U3JJK0
names: Subcellular Location Annotation
messages: Nucleus

59894:PFKFB2
gene id: 59894:PFKFB2
uniprot id: A0A803VP83
uniprot id: A0A803W5N8
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

59894:USP3
gene id: 59894:USP3
uniprot id: A0A803WDG1
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:STS
gene id: 59894:STS
uniprot id: A0A803W198
names: Similarity
messages: Belongs to the sulfatase family.

59894:TFEB
gene id: 59894:TFEB
uniprot id: U3JKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

59894:CLDN10
gene id: 59894:CLDN10
uniprot id: A0A803W2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:KHDRBS3
gene id: 59894:KHDRBS3
uniprot id: U3JJB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDRBS family.
messages: Cytoplasm

59894:GINS2
gene id: 59894:GINS2
uniprot id: A0A803VE78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

59894:TMEM2
gene id: 59894:TMEM2
uniprot id: U3K865
names: Similarity
messages: Belongs to the CEMIP family.

59894:PRPS2
gene id: 59894:PRPS2
uniprot id: A0A803W375
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

59894:EMP2
gene id: 59894:EMP2
uniprot id: A0A803VVW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

59894:NOX4
gene id: 59894:NOX4
uniprot id: A0A803V169
names: Subcellular Location Annotation
messages: Membrane

59894:TMLHE
gene id: 59894:TMLHE
uniprot id: U3KAD8
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

59894:MAP2K3
gene id: 59894:MAP2K3
uniprot id: A0A803VFU8
uniprot id: U3KH91
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:AMIGO3
gene id: 59894:AMIGO3
uniprot id: U3KIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

59894:HACD4
gene id: 59894:HACD4
uniprot id: A0A803VK08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:GAL
gene id: 59894:GAL
uniprot id: U3KDP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

59894:RPL6
gene id: 59894:RPL6
uniprot id: U3K2U5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

59894:TMEM38B
gene id: 59894:TMEM38B
uniprot id: U3JJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

59894:C5H14orf166
gene id: 59894:C5H14orf166
uniprot id: U3JGV8
names: Similarity
messages: Belongs to the RTRAF family.

59894:NOVA1
gene id: 59894:NOVA1
uniprot id: A0A803V078
uniprot id: A0A803VGW5
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

59894:LPIN1
gene id: 59894:LPIN1
uniprot id: A0A803VM34
uniprot id: A0A803VUE8
names: Similarity
messages: Belongs to the lipin family.

59894:PDLIM3
gene id: 59894:PDLIM3
uniprot id: A0A803VKR2
uniprot id: A0A803VT63
uniprot id: A0A803VXY5
names: Subcellular Location Annotation
messages: Z line

59894:AKAP12
gene id: 59894:AKAP12
uniprot id: U3KCN0
names: Subcellular Location Annotation
messages: Membrane

59894:PDCD4
gene id: 59894:PDCD4
uniprot id: U3JHX1
names: Similarity
messages: Belongs to the PDCD4 family.

59894:CAV1
gene id: 59894:CAV1
uniprot id: U3K695
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

59894:DOCK9
gene id: 59894:DOCK9
uniprot id: A0A803VQ98
names: Similarity
messages: Belongs to the DOCK family.

59894:FAM72A
gene id: 59894:FAM72A
uniprot id: U3JCT8
names: Similarity
messages: Belongs to the FAM72 family.

59894:HSP90AA1
gene id: 59894:HSP90AA1
uniprot id: U3JJA1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

59894:AGO2
gene id: 59894:AGO2
uniprot id: U3JJK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

59894:ATP9B
gene id: 59894:ATP9B
uniprot id: A0A803WAE6
uniprot id: A0A803WC89
uniprot id: U3KFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

59894:PPP4R3A
gene id: 59894:PPP4R3A
uniprot id: A0A803W5D2
names: Similarity
messages: Belongs to the SMEK family.

59894:JPH1
gene id: 59894:JPH1
uniprot id: U3K1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

59894:PTPRG
gene id: 59894:PTPRG
uniprot id: U3KFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

59894:PPCS
gene id: 59894:PPCS
uniprot id: A0A803VBN1
names: Similarity
messages: Belongs to the PPC synthetase family.

59894:FAM234A
gene id: 59894:FAM234A
uniprot id: A0A803VNW7
names: Similarity
messages: Belongs to the FAM234 family.

59894:ND6
gene id: 59894:ND6
uniprot id: Q7GEM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

59894:PTGR1
gene id: 59894:PTGR1
uniprot id: U3JBP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

59894:ENTPD5
gene id: 59894:ENTPD5
uniprot id: U3JUR5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

59894:XPOT
gene id: 59894:XPOT
uniprot id: U3K5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

59894:TMEM230
gene id: 59894:TMEM230
uniprot id: A0A803VPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

59894:THADA
gene id: 59894:THADA
uniprot id: U3KDZ0
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

59894:ALDH18A1
gene id: 59894:ALDH18A1
uniprot id: U3JF52
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

59894:LOC101812422
gene id: 59894:LOC101812422
uniprot id: A0A803V4S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:POLR3B
gene id: 59894:POLR3B
uniprot id: U3KG47
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

59894:RPL27
gene id: 59894:RPL27
uniprot id: U3JDE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

59894:RIMKLB
gene id: 59894:RIMKLB
uniprot id: U3JXT2
names: Similarity
messages: Belongs to the RimK family.

59894:PRPSAP2
gene id: 59894:PRPSAP2
uniprot id: U3KGZ7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

59894:SRPRB
gene id: 59894:SRPRB
uniprot id: U3KFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:TECRL
gene id: 59894:TECRL
uniprot id: U3JTL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

59894:NDRG3
gene id: 59894:NDRG3
uniprot id: A0A803VK75
uniprot id: U3KDJ9
names: Similarity
messages: Belongs to the NDRG family.

59894:GRIA4
gene id: 59894:GRIA4
uniprot id: U3JCE2
uniprot id: U3JCE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

59894:SEPT8
gene id: 59894:SEPT8
uniprot id: U3KG98
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

59894:MED16
gene id: 59894:MED16
uniprot id: U3KHN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

59894:CAP2
gene id: 59894:CAP2
uniprot id: U3KG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

59894:MOS
gene id: 59894:MOS
uniprot id: U3KK77
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:TSTA3
gene id: 59894:TSTA3
uniprot id: A0A803VKN1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

59894:XPO1
gene id: 59894:XPO1
uniprot id: U3K8W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

59894:FAH
gene id: 59894:FAH
uniprot id: U3JTC8
names: Similarity
messages: Belongs to the FAH family.

59894:BICD1
gene id: 59894:BICD1
uniprot id: A0A803V6V7
uniprot id: A0A803VKC0
uniprot id: A0A803VQI2
uniprot id: A0A803WDK1
uniprot id: U3K305
names: Similarity
messages: Belongs to the BicD family.

59894:LCLAT1
gene id: 59894:LCLAT1
uniprot id: A0A803VED9
uniprot id: A0A803WA02
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

59894:COPG1
gene id: 59894:COPG1
uniprot id: U3JZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

59894:LOC101817172
gene id: 59894:LOC101817172
uniprot id: U3KIB0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:ATP6AP1L
gene id: 59894:ATP6AP1L
uniprot id: A0A803VPR1
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

59894:CTSB
gene id: 59894:CTSB
uniprot id: U3JIJ7
names: Similarity
messages: Belongs to the peptidase C1 family.

59894:TRPC5
gene id: 59894:TRPC5
uniprot id: U3K920
names: Subcellular Location Annotation
messages: Membrane

59894:ATG5
gene id: 59894:ATG5
uniprot id: A0A803W9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

59894:CNPY2
gene id: 59894:CNPY2
uniprot id: A0A803W9I4
names: Similarity
messages: Belongs to the canopy family.

59894:MTFR1L
gene id: 59894:MTFR1L
uniprot id: A0A803VSK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

59894:KIAA0391
gene id: 59894:KIAA0391
uniprot id: U3JU12
names: Similarity
messages: Belongs to the PPR family. P subfamily.

59894:ADGRG2
gene id: 59894:ADGRG2
uniprot id: U3JNV7
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101815107
gene id: 59894:LOC101815107
uniprot id: U3JCD0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:EPHX1
gene id: 59894:EPHX1
uniprot id: U3KAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

59894:RPL32
gene id: 59894:RPL32
uniprot id: U3KGV4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

59894:IER3IP1
gene id: 59894:IER3IP1
uniprot id: A0A803VPC1
names: Similarity
messages: Belongs to the YOS1 family.

59894:HOGA1
gene id: 59894:HOGA1
uniprot id: A0A803WEU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

59894:VWC2L
gene id: 59894:VWC2L
uniprot id: A0A803W4N2
names: Subcellular Location Annotation
messages: Synapse

59894:PCBP2
gene id: 59894:PCBP2
uniprot id: U3JJZ9
names: Subcellular Location Annotation
messages: Cytoplasm

59894:RHO
gene id: 59894:RHO
uniprot id: U3KGW6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

59894:TSC22D1
gene id: 59894:TSC22D1
uniprot id: A0A803W3W3
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

59894:ADSL
gene id: 59894:ADSL
uniprot id: U3KCG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

59894:ARL5A
gene id: 59894:ARL5A
uniprot id: A0A803W6M7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

59894:LOC101816519
gene id: 59894:LOC101816519
uniprot id: U3K5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

59894:STEAP1
gene id: 59894:STEAP1
uniprot id: A0A803VPJ3
names: Subcellular Location Annotation
messages: Membrane

59894:FAM76B
gene id: 59894:FAM76B
uniprot id: U3JC39
names: Similarity
messages: Belongs to the FAM76 family.

59894:TSSK2
gene id: 59894:TSSK2
uniprot id: U3KLD8
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:IL1RAPL2
gene id: 59894:IL1RAPL2
uniprot id: U3JG17
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

59894:RNGTT
gene id: 59894:RNGTT
uniprot id: A0A803VN86
uniprot id: U3JJY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

59894:CXXC5
gene id: 59894:CXXC5
uniprot id: U3K4B7
names: Subcellular Location Annotation
messages: Cytoplasm

59894:COPS7B
gene id: 59894:COPS7B
uniprot id: U3JYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

59894:EREG
gene id: 59894:EREG
uniprot id: U3K0D3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ADCY5
gene id: 59894:ADCY5
uniprot id: U3KFY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

59894:CSNK1A1
gene id: 59894:CSNK1A1
uniprot id: A0A803VHX7
uniprot id: A0A803W380
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:LOC101818814
gene id: 59894:LOC101818814
uniprot id: U3KHJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

59894:IP6K3
gene id: 59894:IP6K3
uniprot id: U3JMM5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

59894:TYW3
gene id: 59894:TYW3
uniprot id: A0A803VIE7
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

59894:COX1
gene id: 59894:COX1
uniprot id: S0ASK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

59894:FAM73B
gene id: 59894:FAM73B
uniprot id: U3JFD5
names: Similarity
messages: Belongs to the mitoguardin family.

59894:DDR2
gene id: 59894:DDR2
uniprot id: U3JLM1
names: Subcellular Location Annotation
messages: Membrane

59894:ATP7B
gene id: 59894:ATP7B
uniprot id: U3K1J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

59894:GJC1
gene id: 59894:GJC1
uniprot id: U3KIS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:EXO1
gene id: 59894:EXO1
uniprot id: U3KFA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

59894:OBFC1
gene id: 59894:OBFC1
uniprot id: U3K2B7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

59894:ANKZF1
gene id: 59894:ANKZF1
uniprot id: A0A803VPN4
uniprot id: U3JNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

59894:KCNJ12
gene id: 59894:KCNJ12
uniprot id: A0A803VD75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

59894:PRKAB1
gene id: 59894:PRKAB1
uniprot id: U3JZ16
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

59894:LOC101815017
gene id: 59894:LOC101815017
uniprot id: A0A803W0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

59894:PLXNA1
gene id: 59894:PLXNA1
uniprot id: U3JZI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:LOC101822280
gene id: 59894:LOC101822280
uniprot id: U3K542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

59894:BTF3
gene id: 59894:BTF3
uniprot id: U3K6L2
names: Similarity
messages: Belongs to the NAC-beta family.

59894:IARS
gene id: 59894:IARS
uniprot id: U3K6P5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

59894:GCNT1
gene id: 59894:GCNT1
uniprot id: U3KJH7
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

59894:COQ10B
gene id: 59894:COQ10B
uniprot id: U3JNU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

59894:LOC101805977
gene id: 59894:LOC101805977
uniprot id: U3JNR4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:CSTA
gene id: 59894:CSTA
uniprot id: A0A803VVE0
names: Similarity
messages: Belongs to the cystatin family.

59894:DDX24
gene id: 59894:DDX24
uniprot id: A0A803V145
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

59894:CDC42BPB
gene id: 59894:CDC42BPB
uniprot id: A0A803VS94
uniprot id: U3JJF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

59894:LOC101816713
gene id: 59894:LOC101816713
uniprot id: U3JWY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

59894:MAP7
gene id: 59894:MAP7
uniprot id: A0A803VAC5
names: Similarity
messages: Belongs to the MAP7 family.

59894:JAG2
gene id: 59894:JAG2
uniprot id: A0A803WBX8
uniprot id: U3JKA8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

59894:VRTN
gene id: 59894:VRTN
uniprot id: U3KLE1
names: Similarity
messages: Belongs to the vertnin family.

59894:LOC101818212
gene id: 59894:LOC101818212
uniprot id: U3JNM5
names: Similarity
messages: Belongs to the sulfatase family.

59894:RAD50
gene id: 59894:RAD50
uniprot id: U3KG88
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

59894:STXBP5
gene id: 59894:STXBP5
uniprot id: A0A803V7C6
uniprot id: A0A803VTI5
uniprot id: U3KF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

59894:SERPINE2
gene id: 59894:SERPINE2
uniprot id: A0A803V7Y9
uniprot id: U3JWB2
names: Similarity
messages: Belongs to the serpin family.

59894:FAM91A1
gene id: 59894:FAM91A1
uniprot id: U3JII8
names: Similarity
messages: Belongs to the FAM91 family.

59894:ERBB4
gene id: 59894:ERBB4
uniprot id: A0A803WA59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

59894:INO80D
gene id: 59894:INO80D
uniprot id: U3JMJ7
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101812429
gene id: 59894:LOC101812429
uniprot id: A0A803W4T2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:CFH
gene id: 59894:CFH
uniprot id: A0A803VUS6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101809996
gene id: 59894:LOC101809996
uniprot id: U3JNA0
names: Similarity
messages: Belongs to the globin family.

59894:HNRNPR
gene id: 59894:HNRNPR
uniprot id: A0A803VUJ9
names: Subcellular Location Annotation
messages: Cytoplasm

59894:SDHD
gene id: 59894:SDHD
uniprot id: U3JUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

59894:P2RX1
gene id: 59894:P2RX1
uniprot id: U3K5D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

59894:XRCC6
gene id: 59894:XRCC6
uniprot id: U3KBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

59894:GPER1
gene id: 59894:GPER1
uniprot id: U3KIL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:OSGEPL1
gene id: 59894:OSGEPL1
uniprot id: U3JP94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

59894:LOC101817939
gene id: 59894:LOC101817939
uniprot id: U3JWR6
names: Subcellular Location Annotation
messages: Membrane
messages: Membrane raft
messages: Secreted

59894:DDX6
gene id: 59894:DDX6
uniprot id: U3K5F1
names: Similarity
messages: Belongs to the DEAD box helicase family.

59894:NAGA
gene id: 59894:NAGA
uniprot id: U3KB71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

59894:FAM189B
gene id: 59894:FAM189B
uniprot id: U3JJR0
names: Similarity
messages: Belongs to the ENTREP family.

59894:ERI1
gene id: 59894:ERI1
uniprot id: A0A803WA18
names: Subcellular Location Annotation
messages: Cytoplasm

59894:CTLA4
gene id: 59894:CTLA4
uniprot id: U3JM89
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

59894:PKM
gene id: 59894:PKM
uniprot id: A0A803VBL7
uniprot id: U3K4X2
names: Similarity
messages: Belongs to the pyruvate kinase family.

59894:CDIP1
gene id: 59894:CDIP1
uniprot id: A0A803V9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

59894:STARD13
gene id: 59894:STARD13
uniprot id: A0A803V5V3
uniprot id: A0A803VM20
uniprot id: U3K148
names: Subcellular Location Annotation
messages: Cytoplasm

59894:C15H12orf49
gene id: 59894:C15H12orf49
uniprot id: A0A803VAP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

59894:LOC101819992
gene id: 59894:LOC101819992
uniprot id: U3JTK8
names: Similarity
messages: Belongs to the CD200R family.

59894:MAPK1IP1L
gene id: 59894:MAPK1IP1L
uniprot id: A0A803V293
names: Similarity
messages: Belongs to the MISS family.

59894:PLXNB1
gene id: 59894:PLXNB1
uniprot id: U3KE08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:CPLX1
gene id: 59894:CPLX1
uniprot id: U3JE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

59894:SNX30
gene id: 59894:SNX30
uniprot id: U3JBH0
names: Similarity
messages: Belongs to the sorting nexin family.

59894:LOC101817208
gene id: 59894:LOC101817208
uniprot id: A0A803V733
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

59894:SLC4A10
gene id: 59894:SLC4A10
uniprot id: A0A803VA55
uniprot id: A0A803VEM0
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

59894:ZDHHC14
gene id: 59894:ZDHHC14
uniprot id: U3KDJ7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:DCAF13
gene id: 59894:DCAF13
uniprot id: U3JTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

59894:RPS27A
gene id: 59894:RPS27A
uniprot id: A0A803V5N6
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

59894:PHKG1
gene id: 59894:PHKG1
uniprot id: U3JWB6
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

59894:STARD3
gene id: 59894:STARD3
uniprot id: U3JCR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

59894:SLC12A4
gene id: 59894:SLC12A4
uniprot id: A0A803W1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

59894:INCENP
gene id: 59894:INCENP
uniprot id: U3KA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

59894:TPM2
gene id: 59894:TPM2
uniprot id: U3JHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

59894:CLDN20
gene id: 59894:CLDN20
uniprot id: U3KKK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:ETS1
gene id: 59894:ETS1
uniprot id: U3JQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

59894:SNX10
gene id: 59894:SNX10
uniprot id: A0A803VSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

59894:ADAM19
gene id: 59894:ADAM19
uniprot id: U3K1B6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:HESX1
gene id: 59894:HESX1
uniprot id: U3K1E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

59894:BANP
gene id: 59894:BANP
uniprot id: A0A803V551
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

59894:TH
gene id: 59894:TH
uniprot id: U3KAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

59894:SEC16B
gene id: 59894:SEC16B
uniprot id: U3K0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

59894:LOC101813448
gene id: 59894:LOC101813448
uniprot id: U3K440
names: Subcellular Location Annotation
messages: Membrane

59894:DDX43
gene id: 59894:DDX43
uniprot id: A0A803V052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: Cytoplasm

59894:TEF
gene id: 59894:TEF
uniprot id: U3KBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

59894:MST1R
gene id: 59894:MST1R
uniprot id: U3K2W1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:FAM69B
gene id: 59894:FAM69B
uniprot id: U3JG58
names: Similarity
messages: Belongs to the DIPK family.

59894:PISD
gene id: 59894:PISD
uniprot id: U3JY89
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

59894:SMC4
gene id: 59894:SMC4
uniprot id: U3JF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Chromosome
messages: Nucleus

59894:CPM
gene id: 59894:CPM
uniprot id: U3K6C3
names: Similarity
messages: Belongs to the peptidase M14 family.

59894:ANAPC11
gene id: 59894:ANAPC11
uniprot id: A0A803W2Y4
names: Similarity
messages: Belongs to the RING-box family.

59894:ABL2
gene id: 59894:ABL2
uniprot id: A0A803VWJ5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:LOC101818144
gene id: 59894:LOC101818144
uniprot id: U3KI73
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:GPR146
gene id: 59894:GPR146
uniprot id: U3KIL9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:MLST8
gene id: 59894:MLST8
uniprot id: U3JLW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

59894:RPRD1A
gene id: 59894:RPRD1A
uniprot id: A0A803V0D5
uniprot id: A0A803WBP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

59894:ADAMTS6
gene id: 59894:ADAMTS6
uniprot id: U3K566
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

59894:LOC101807707
gene id: 59894:LOC101807707
uniprot id: A0A803VIB9
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:EPC1
gene id: 59894:EPC1
uniprot id: A0A803V1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

59894:KIF3B
gene id: 59894:KIF3B
uniprot id: A0A803W926
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:SPOPL
gene id: 59894:SPOPL
uniprot id: A0A803WFP6
names: Similarity
messages: Belongs to the Tdpoz family.

59894:DGKB
gene id: 59894:DGKB
uniprot id: A0A803WGH6
uniprot id: U3K5V3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

59894:LOC101820822
gene id: 59894:LOC101820822
uniprot id: U3K091
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

59894:CEP57
gene id: 59894:CEP57
uniprot id: U3JC40
names: Similarity
messages: Belongs to the translokin family.

59894:SLC25A48
gene id: 59894:SLC25A48
uniprot id: U3JZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:GAREM1
gene id: 59894:GAREM1
uniprot id: A0A803V7S9
names: Similarity
messages: Belongs to the GAREM family.

59894:RAB9A
gene id: 59894:RAB9A
uniprot id: U3KL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

59894:SKA2
gene id: 59894:SKA2
uniprot id: U3JSV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

59894:LOC101817753
gene id: 59894:LOC101817753
uniprot id: U3K4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

59894:CITED4
gene id: 59894:CITED4
uniprot id: U3KIP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

59894:GRB14
gene id: 59894:GRB14
uniprot id: U3K0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

59894:LOC101816363
gene id: 59894:LOC101816363
uniprot id: U3K5X1
names: Similarity
messages: Belongs to the SLBP family.

59894:FGF13
gene id: 59894:FGF13
uniprot id: A0A803VX76
uniprot id: U3JMD9
uniprot id: U3JME2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

59894:TADA2A
gene id: 59894:TADA2A
uniprot id: U3JRP3
names: Subcellular Location Annotation
messages: Nucleus

59894:DUSP1
gene id: 59894:DUSP1
uniprot id: U3K2F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

59894:LOC101811783
gene id: 59894:LOC101811783
uniprot id: A0A803W473
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

59894:PRPF18
gene id: 59894:PRPF18
uniprot id: A0A803VAF6
uniprot id: U3JGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

59894:CDK14
gene id: 59894:CDK14
uniprot id: A0A803V4P1
uniprot id: A0A803VBA6
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:NCF2
gene id: 59894:NCF2
uniprot id: U3JK78
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

59894:LOC101809491
gene id: 59894:LOC101809491
uniprot id: U3JC51
names: Similarity
messages: Belongs to the intermediate filament family.

59894:KIF13B
gene id: 59894:KIF13B
uniprot id: A0A803VDU8
uniprot id: U3K8I1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:ESCO1
gene id: 59894:ESCO1
uniprot id: U3JUH9
names: Subcellular Location Annotation
messages: Nucleus

59894:DOLK
gene id: 59894:DOLK
uniprot id: U3KLH9
names: Similarity
messages: Belongs to the polyprenol kinase family.

59894:SEPT5
gene id: 59894:SEPT5
uniprot id: A0A803W5K4
uniprot id: A0A803WAA0
uniprot id: U3K015
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

59894:HNF1A
gene id: 59894:HNF1A
uniprot id: U3JYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

59894:TAX1BP3
gene id: 59894:TAX1BP3
uniprot id: U3JU11
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

59894:HOXA3
gene id: 59894:HOXA3
uniprot id: U3K4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

59894:OXSM
gene id: 59894:OXSM
uniprot id: U3K3H5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

59894:ENTPD8
gene id: 59894:ENTPD8
uniprot id: U3JRJ5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

59894:TROVE2
gene id: 59894:TROVE2
uniprot id: U3JJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

59894:TBCE
gene id: 59894:TBCE
uniprot id: U3KGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

59894:ESRRB
gene id: 59894:ESRRB
uniprot id: A0A803V803
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

59894:NME8
gene id: 59894:NME8
uniprot id: U3JJI5
names: Similarity
messages: Belongs to the NDK family.

59894:LOC101813624
gene id: 59894:LOC101813624
uniprot id: U3JM97
uniprot id: U3JM98
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

59894:CACNB3
gene id: 59894:CACNB3
uniprot id: U3JBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

59894:LOC101810322
gene id: 59894:LOC101810322
uniprot id: U3JBK4
names: Similarity
messages: Belongs to the hexokinase family.

59894:SLC16A9
gene id: 59894:SLC16A9
uniprot id: U3JHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane

59894:XDH
gene id: 59894:XDH
uniprot id: U3KAG6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

59894:HMGCS2
gene id: 59894:HMGCS2
uniprot id: A0A803VQM2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

59894:COQ10A
gene id: 59894:COQ10A
uniprot id: U3JCK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

59894:GLI2
gene id: 59894:GLI2
uniprot id: U3KFK1
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

59894:FUT9
gene id: 59894:FUT9
uniprot id: U3K4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

59894:PITX2
gene id: 59894:PITX2
uniprot id: A0A803WGM6
uniprot id: U3JVG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

59894:NTMT1
gene id: 59894:NTMT1
uniprot id: U3JFE0
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

59894:XRCC4
gene id: 59894:XRCC4
uniprot id: A0A803WCY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

59894:ARRB1
gene id: 59894:ARRB1
uniprot id: U3JUQ6
names: Similarity
messages: Belongs to the arrestin family.

59894:NAPG
gene id: 59894:NAPG
uniprot id: A0A803VAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

59894:VPS41
gene id: 59894:VPS41
uniprot id: A0A803V8H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

59894:LOC101814550
gene id: 59894:LOC101814550
uniprot id: A0A803WA26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

59894:MEP1A
gene id: 59894:MEP1A
uniprot id: U3JFS4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:ASCC3
gene id: 59894:ASCC3
uniprot id: U3JRS3
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

59894:FOXJ2
gene id: 59894:FOXJ2
uniprot id: A0A803WG65
names: Subcellular Location Annotation
messages: Nucleus

59894:CORO6
gene id: 59894:CORO6
uniprot id: A0A803V964
uniprot id: A0A803WAV2
uniprot id: U3JUP6
names: Similarity
messages: Belongs to the WD repeat coronin family.

59894:LOC101817656
gene id: 59894:LOC101817656
uniprot id: U3KJL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:DUS4L
gene id: 59894:DUS4L
uniprot id: A0A803VGD6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

59894:LOC101818819
gene id: 59894:LOC101818819
uniprot id: U3JE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:MAPRE2
gene id: 59894:MAPRE2
uniprot id: U3JTJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

59894:APIP
gene id: 59894:APIP
uniprot id: A0A803VY89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

59894:FAM118B
gene id: 59894:FAM118B
uniprot id: U3JR35
names: Similarity
messages: Belongs to the FAM118 family.

59894:ATP6V0A4
gene id: 59894:ATP6V0A4
uniprot id: U3K337
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

59894:RGS9BP
gene id: 59894:RGS9BP
uniprot id: U3KIF9
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

59894:MAT2B
gene id: 59894:MAT2B
uniprot id: A0A803VN44
uniprot id: U3KGJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

59894:BCL2L13
gene id: 59894:BCL2L13
uniprot id: U3K4U1
names: Similarity
messages: Belongs to the Bcl-2 family.

59894:AKR1D1
gene id: 59894:AKR1D1
uniprot id: U3JM21
names: Similarity
messages: Belongs to the aldo/keto reductase family.

59894:TMEM35
gene id: 59894:TMEM35
uniprot id: U3KAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

59894:STEAP2
gene id: 59894:STEAP2
uniprot id: A0A803VWB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

59894:SERINC3
gene id: 59894:SERINC3
uniprot id: U3JRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

59894:SCFD1
gene id: 59894:SCFD1
uniprot id: U3JTE9
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

59894:LOC101819515
gene id: 59894:LOC101819515
uniprot id: U3K8K7
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:WNT3
gene id: 59894:WNT3
uniprot id: A0A803WDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:ZFPM2
gene id: 59894:ZFPM2
uniprot id: A0A803VMS2
names: Subcellular Location Annotation
messages: Nucleus

59894:MTRF1
gene id: 59894:MTRF1
uniprot id: U3K030
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

59894:HAP1
gene id: 59894:HAP1
uniprot id: A0A803V3K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

59894:LYRM4
gene id: 59894:LYRM4
uniprot id: U3KFD8
names: Similarity
messages: Belongs to the complex I LYR family.

59894:TASP1
gene id: 59894:TASP1
uniprot id: A0A803VXL4
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

59894:DOCK5
gene id: 59894:DOCK5
uniprot id: A0A803W4S7
names: Similarity
messages: Belongs to the DOCK family.

59894:PRKG2
gene id: 59894:PRKG2
uniprot id: U3JTC2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

59894:TBX1
gene id: 59894:TBX1
uniprot id: A0A803WBD8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

59894:SLC29A1
gene id: 59894:SLC29A1
uniprot id: A0A803VGS4
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

59894:INPP5A
gene id: 59894:INPP5A
uniprot id: A0A803VGZ2
uniprot id: A0A803WAW6
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

59894:GRIA2
gene id: 59894:GRIA2
uniprot id: A0A803V671
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

59894:SLC46A2
gene id: 59894:SLC46A2
uniprot id: U3JBG8
names: Subcellular Location Annotation
messages: Membrane

59894:DPY19L4
gene id: 59894:DPY19L4
uniprot id: A0A803VF20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

59894:TBL3
gene id: 59894:TBL3
uniprot id: U3JLC3
names: Subcellular Location Annotation
messages: nucleolus

59894:PLA2G4A
gene id: 59894:PLA2G4A
uniprot id: A0A803VZZ0
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

59894:LAP3
gene id: 59894:LAP3
uniprot id: U3K3N9
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

59894:NUP205
gene id: 59894:NUP205
uniprot id: A0A803V6H2
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

59894:TFAP2B
gene id: 59894:TFAP2B
uniprot id: A0A803WCW7
names: Similarity
messages: Belongs to the AP-2 family.

59894:HEBP1
gene id: 59894:HEBP1
uniprot id: A0A803WFF0
names: Similarity
messages: Belongs to the HEBP family.

59894:TGIF1
gene id: 59894:TGIF1
uniprot id: A0A803V8W7
names: Subcellular Location Annotation
messages: Nucleus

59894:FABP2
gene id: 59894:FABP2
uniprot id: U3JDR3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:RNF145
gene id: 59894:RNF145
uniprot id: A0A803VVT3
names: Subcellular Location Annotation
messages: Membrane

59894:CCDC90B
gene id: 59894:CCDC90B
uniprot id: U3JZ69
names: Similarity
messages: Belongs to the CCDC90 family.

59894:SNX5
gene id: 59894:SNX5
uniprot id: U3JYQ5
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

59894:CLN8
gene id: 59894:CLN8
uniprot id: A0A803VT31
names: Subcellular Location Annotation
messages: Membrane

59894:PSMC5
gene id: 59894:PSMC5
uniprot id: U3KGR3
names: Similarity
messages: Belongs to the AAA ATPase family.

59894:TSPAN32
gene id: 59894:TSPAN32
uniprot id: A0A803VD72
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:LOC101813851
gene id: 59894:LOC101813851
uniprot id: A0A803VW25
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

59894:LOC101820119
gene id: 59894:LOC101820119
uniprot id: A0A803VTX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:GGT7
gene id: 59894:GGT7
uniprot id: A0A803VK00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

59894:CD82
gene id: 59894:CD82
uniprot id: U3KCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:MRPL44
gene id: 59894:MRPL44
uniprot id: U3JWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

59894:PRICKLE1
gene id: 59894:PRICKLE1
uniprot id: U3K6N7
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

59894:NETO1
gene id: 59894:NETO1
uniprot id: U3JPW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:HEBP2
gene id: 59894:HEBP2
uniprot id: U3JK01
names: Similarity
messages: Belongs to the HEBP family.

59894:METTL11B
gene id: 59894:METTL11B
uniprot id: U3JZL2
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

59894:HUS1
gene id: 59894:HUS1
uniprot id: U3KFE5
names: Similarity
messages: Belongs to the HUS1 family.

59894:HVCN1
gene id: 59894:HVCN1
uniprot id: U3K331
names: Subcellular Location Annotation
messages: Membrane

59894:MEOX2
gene id: 59894:MEOX2
uniprot id: U3K5U7
names: Subcellular Location Annotation
messages: Nucleus

59894:VPS37A
gene id: 59894:VPS37A
uniprot id: U3KA03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

59894:NCDN
gene id: 59894:NCDN
uniprot id: U3JDB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

59894:NDUFV1
gene id: 59894:NDUFV1
uniprot id: U3JF28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

59894:MCM10
gene id: 59894:MCM10
uniprot id: U3JGS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

59894:NIPAL1
gene id: 59894:NIPAL1
uniprot id: A0A803VPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

59894:COQ9
gene id: 59894:COQ9
uniprot id: A0A803VDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

59894:LOC107604579
gene id: 59894:LOC107604579
uniprot id: U3KKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:C1HXorf23
gene id: 59894:C1HXorf23
uniprot id: U3JNN7
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

59894:ATP2A2
gene id: 59894:ATP2A2
uniprot id: A0A803W5X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

59894:GHSR
gene id: 59894:GHSR
uniprot id: U3K1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:IFITM10
gene id: 59894:IFITM10
uniprot id: U3KB40
names: Similarity
messages: Belongs to the CD225/Dispanin family.

59894:CSNK1G2
gene id: 59894:CSNK1G2
uniprot id: A0A803VHL4
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

59894:ISCA1
gene id: 59894:ISCA1
uniprot id: A0A803VC20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

59894:LOC101810223
gene id: 59894:LOC101810223
uniprot id: U3KFT7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

59894:LHX1
gene id: 59894:LHX1
uniprot id: U3JRU9
names: Subcellular Location Annotation
messages: Nucleus

59894:TALDO1
gene id: 59894:TALDO1
uniprot id: A0A803VL83
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

59894:FBXO9
gene id: 59894:FBXO9
uniprot id: U3JGM7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9).
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and acts as a regulator of mTOR signaling.

59894:LOC101822184
gene id: 59894:LOC101822184
uniprot id: A0A803VKW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

59894:OGN
gene id: 59894:OGN
uniprot id: U3K349
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

59894:LOC101817957
gene id: 59894:LOC101817957
uniprot id: A0A803VW13
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:RAB39B
gene id: 59894:RAB39B
uniprot id: A0A803W210
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

59894:NEK3
gene id: 59894:NEK3
uniprot id: U3K1L2
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:CITED2
gene id: 59894:CITED2
uniprot id: U3KKR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

59894:MBP
gene id: 59894:MBP
uniprot id: A0A803W4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

59894:RPL26L1
gene id: 59894:RPL26L1
uniprot id: U3K2E2
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

59894:LOC101819878
gene id: 59894:LOC101819878
uniprot id: A0A803VV12
uniprot id: U3JUN4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

59894:CELF2
gene id: 59894:CELF2
uniprot id: A0A803V3U6
uniprot id: A0A803VXR6
uniprot id: A0A803WH04
uniprot id: U3JGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

59894:STAT3
gene id: 59894:STAT3
uniprot id: A0A803VXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

59894:LOC101821224
gene id: 59894:LOC101821224
uniprot id: U3KL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:F2R
gene id: 59894:F2R
uniprot id: U3K607
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LPAR1
gene id: 59894:LPAR1
uniprot id: U3JBU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

59894:TAF12
gene id: 59894:TAF12
uniprot id: U3JF79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

59894:RBFOX1
gene id: 59894:RBFOX1
uniprot id: A0A803VXM0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

59894:BAIAP2
gene id: 59894:BAIAP2
uniprot id: U3KDM8
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

59894:KCNAB1
gene id: 59894:KCNAB1
uniprot id: A0A803V0A5
uniprot id: U3JQH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

59894:CNIH3
gene id: 59894:CNIH3
uniprot id: U3KB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

59894:PDIK1L
gene id: 59894:PDIK1L
uniprot id: A0A803V3Q3
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:T
gene id: 59894:T
uniprot id: U3KCL7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

59894:INTS9
gene id: 59894:INTS9
uniprot id: A0A803VLD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

59894:TRIAP1
gene id: 59894:TRIAP1
uniprot id: U3JYN8
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

59894:TMEM45A
gene id: 59894:TMEM45A
uniprot id: A0A803VCP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

59894:TEKT3
gene id: 59894:TEKT3
uniprot id: U3K4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

59894:PDYN
gene id: 59894:PDYN
uniprot id: A0A803V5L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opioid activity and may have anti-apoptotic effect.
messages: Secreted

59894:PPP2R5A
gene id: 59894:PPP2R5A
uniprot id: U3KD64
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

59894:PDZK1IP1
gene id: 59894:PDZK1IP1
uniprot id: U3K3V4
names: Subcellular Location Annotation
messages: Membrane

59894:OTC
gene id: 59894:OTC
uniprot id: U3JFT8
uniprot id: U3JFU0
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

59894:PIK3R3
gene id: 59894:PIK3R3
uniprot id: U3K4G9
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

59894:GRID1
gene id: 59894:GRID1
uniprot id: U3JVW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

59894:SSH1
gene id: 59894:SSH1
uniprot id: U3K2I7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

59894:LOC101818143
gene id: 59894:LOC101818143
uniprot id: U3JSA5
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:POMK
gene id: 59894:POMK
uniprot id: U3JVJ2
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

59894:YTHDF3
gene id: 59894:YTHDF3
uniprot id: U3JSI1
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

59894:LOC101812793
gene id: 59894:LOC101812793
uniprot id: U3JH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

59894:HHATL
gene id: 59894:HHATL
uniprot id: U3JE59
names: Subcellular Location Annotation
messages: Membrane

59894:WSCD2
gene id: 59894:WSCD2
uniprot id: U3K2P5
names: Function
names: Similarity
messages: Belongs to the WSCD family.
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

59894:CAPN3
gene id: 59894:CAPN3
uniprot id: A0A803VGL6
uniprot id: U3JT66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

59894:GJA8
gene id: 59894:GJA8
uniprot id: U3KJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:POLR1A
gene id: 59894:POLR1A
uniprot id: U3K665
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

59894:INSR
gene id: 59894:INSR
uniprot id: U3KHF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

59894:FMR1
gene id: 59894:FMR1
uniprot id: U3KC61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Stress granule
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

59894:BROX
gene id: 59894:BROX
uniprot id: U3KBW9
names: Similarity
messages: Belongs to the BROX family.

59894:LOC101813356
gene id: 59894:LOC101813356
uniprot id: A0A803VTC6
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:PLAT
gene id: 59894:PLAT
uniprot id: A0A803VAU6
uniprot id: U3JV78
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:PLPPR5
gene id: 59894:PLPPR5
uniprot id: A0A803VJK0
uniprot id: A0A803W3D4
uniprot id: A0A803WCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

59894:WDR44
gene id: 59894:WDR44
uniprot id: U3JGG6
names: Subcellular Location Annotation
messages: trans-Golgi network

59894:B4GALNT4
gene id: 59894:B4GALNT4
uniprot id: U3KAH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

59894:MMP16
gene id: 59894:MMP16
uniprot id: U3JRD6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

59894:POMT2
gene id: 59894:POMT2
uniprot id: A0A803VEE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

59894:LOC101816250
gene id: 59894:LOC101816250
uniprot id: U3JG77
names: Similarity
messages: Belongs to the HEBP family.

59894:FATE1
gene id: 59894:FATE1
uniprot id: U3K9H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

59894:GPR39
gene id: 59894:GPR39
uniprot id: A0A803VBB8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:EPHB6
gene id: 59894:EPHB6
uniprot id: U3JPE3
names: Subcellular Location Annotation
messages: Membrane

59894:LIPG
gene id: 59894:LIPG
uniprot id: U3K2V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:CCDC53
gene id: 59894:CCDC53
uniprot id: A0A803VX15
names: Similarity
messages: Belongs to the CCDC53 family.

59894:C6H10orf90
gene id: 59894:C6H10orf90
uniprot id: U3JEB0
names: Subcellular Location Annotation
messages: centrosome

59894:IFT57
gene id: 59894:IFT57
uniprot id: A0A803V514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

59894:GATA5
gene id: 59894:GATA5
uniprot id: U3K7K2
names: Subcellular Location Annotation
messages: Nucleus

59894:EDEM2
gene id: 59894:EDEM2
uniprot id: U3JTI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

59894:LOC101810444
gene id: 59894:LOC101810444
uniprot id: U3K834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

59894:STMN3
gene id: 59894:STMN3
uniprot id: U3JTM4
names: Similarity
messages: Belongs to the stathmin family.

59894:ACOX3
gene id: 59894:ACOX3
uniprot id: U3K4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

59894:NDST1
gene id: 59894:NDST1
uniprot id: A0A803VRE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

59894:LOC101806955
gene id: 59894:LOC101806955
uniprot id: U3JZJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:PLBD1
gene id: 59894:PLBD1
uniprot id: U3KAF2
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

59894:PTHLH
gene id: 59894:PTHLH
uniprot id: U3JPV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

59894:LOC101821682
gene id: 59894:LOC101821682
uniprot id: A0A803VXK9
uniprot id: U3JU55
names: Subcellular Location Annotation
messages: Membrane

59894:PLD5
gene id: 59894:PLD5
uniprot id: U3KA26
names: Similarity
messages: Belongs to the phospholipase D family.

59894:LOC101809715
gene id: 59894:LOC101809715
uniprot id: U3JMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:SENP7
gene id: 59894:SENP7
uniprot id: A0A803VAU2
uniprot id: A0A803VM09
uniprot id: A0A803W682
uniprot id: U3JVH1
names: Similarity
messages: Belongs to the peptidase C48 family.

59894:SGSH
gene id: 59894:SGSH
uniprot id: A0A803WFX2
names: Similarity
messages: Belongs to the sulfatase family.

59894:PRRX2
gene id: 59894:PRRX2
uniprot id: U3JFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

59894:PAPOLA
gene id: 59894:PAPOLA
uniprot id: A0A803W7Q5
uniprot id: U3JIP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

59894:TRRAP
gene id: 59894:TRRAP
uniprot id: U3KHR8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

59894:LHPP
gene id: 59894:LHPP
uniprot id: U3JQE2
uniprot id: U3JQE3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

59894:SUB1
gene id: 59894:SUB1
uniprot id: U3JHH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

59894:LOC101816509
gene id: 59894:LOC101816509
uniprot id: A0A803VDK8
uniprot id: U3K045
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:CCDC58
gene id: 59894:CCDC58
uniprot id: U3JQV0
names: Similarity
messages: Belongs to the MIX23 family.

59894:GGT5
gene id: 59894:GGT5
uniprot id: U3JXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

59894:GPCPD1
gene id: 59894:GPCPD1
uniprot id: A0A803V0T6
uniprot id: A0A803VW46
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

59894:ATP2C1
gene id: 59894:ATP2C1
uniprot id: A0A803W7M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:LOC101818310
gene id: 59894:LOC101818310
uniprot id: U3JLF6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

59894:ABAT
gene id: 59894:ABAT
uniprot id: U3JN19
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

59894:GLA
gene id: 59894:GLA
uniprot id: A0A803VJB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

59894:IFI30
gene id: 59894:IFI30
uniprot id: U3KHD7
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

59894:LOC107604580
gene id: 59894:LOC107604580
uniprot id: U3KKS0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:GALR2
gene id: 59894:GALR2
uniprot id: U3JE16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

59894:ZNF277
gene id: 59894:ZNF277
uniprot id: U3K4E2
names: Similarity
messages: Belongs to the ZNF277 family.

59894:RYBP
gene id: 59894:RYBP
uniprot id: A0A803W1P3
names: Subcellular Location Annotation
messages: Nucleus

59894:APOO
gene id: 59894:APOO
uniprot id: A0A803WC72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

59894:ADRB2
gene id: 59894:ADRB2
uniprot id: U3KJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

59894:SPPL2B
gene id: 59894:SPPL2B
uniprot id: U3KBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

59894:SYT2
gene id: 59894:SYT2
uniprot id: A0A803W3A1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

59894:LOC101814608
gene id: 59894:LOC101814608
uniprot id: U3JN63
names: Similarity
messages: Belongs to the CNKSR family.

59894:PCSK5
gene id: 59894:PCSK5
uniprot id: A0A803VL98
uniprot id: U3K3C2
names: Similarity
messages: Belongs to the peptidase S8 family.

59894:CD36
gene id: 59894:CD36
uniprot id: U3K7F3
names: Similarity
messages: Belongs to the CD36 family.

59894:SVOP
gene id: 59894:SVOP
uniprot id: U3K2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

59894:LOC101807990
gene id: 59894:LOC101807990
uniprot id: A0A803V439
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

59894:PRPF4B
gene id: 59894:PRPF4B
uniprot id: U3KFC1
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

59894:HMGCR
gene id: 59894:HMGCR
uniprot id: U3K660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

59894:PEPD
gene id: 59894:PEPD
uniprot id: U3JZB3
names: Similarity
messages: Belongs to the peptidase M24B family.

59894:EXOC3L4
gene id: 59894:EXOC3L4
uniprot id: U3JJG1
names: Similarity
messages: Belongs to the SEC6 family.

59894:ATP1B4
gene id: 59894:ATP1B4
uniprot id: U3JFQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

59894:CKAP2L
gene id: 59894:CKAP2L
uniprot id: A0A803V1Y1
names: Similarity
messages: Belongs to the CKAP2 family.

59894:MSTN
gene id: 59894:MSTN
uniprot id: U3JP74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

59894:AACS
gene id: 59894:AACS
uniprot id: U3K466
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

59894:DLL1
gene id: 59894:DLL1
uniprot id: U3JKM5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

59894:NPY
gene id: 59894:NPY
uniprot id: U3KJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

59894:TOM1L2
gene id: 59894:TOM1L2
uniprot id: A0A803VKL8
uniprot id: A0A803VMR5
uniprot id: U3KH54
names: Similarity
messages: Belongs to the TOM1 family.

59894:GPATCH1
gene id: 59894:GPATCH1
uniprot id: U3JZF4
names: Similarity
messages: Belongs to the GPATCH1 family.

59894:GPR89B
gene id: 59894:GPR89B
uniprot id: U3JFJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

59894:LOC101816892
gene id: 59894:LOC101816892
uniprot id: A0A803WE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

59894:CPZ
gene id: 59894:CPZ
uniprot id: U3K512
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:POPDC2
gene id: 59894:POPDC2
uniprot id: A0A803UZV9
uniprot id: A0A803V1T3
names: Similarity
messages: Belongs to the popeye family.

59894:FOXI1
gene id: 59894:FOXI1
uniprot id: U3K4K9
names: Subcellular Location Annotation
messages: Nucleus

59894:PCID2
gene id: 59894:PCID2
uniprot id: U3JKP5
names: Similarity
messages: Belongs to the CSN12 family.

59894:DUPD1
gene id: 59894:DUPD1
uniprot id: A0A803VDK1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

59894:SLC24A2
gene id: 59894:SLC24A2
uniprot id: A0A803V6L7
uniprot id: U3JKA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

59894:DGAT2
gene id: 59894:DGAT2
uniprot id: A0A803WER3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:RARB
gene id: 59894:RARB
uniprot id: U3K3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

59894:LOC101821391
gene id: 59894:LOC101821391
uniprot id: A0A803WE46
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:SLC39A13
gene id: 59894:SLC39A13
uniprot id: U3JV63
names: Subcellular Location Annotation
messages: Membrane

59894:ATAD1
gene id: 59894:ATAD1
uniprot id: U3KF84
names: Similarity
messages: Belongs to the AAA ATPase family.

59894:GPRC5B
gene id: 59894:GPRC5B
uniprot id: A0A803VPE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:RBPJ
gene id: 59894:RBPJ
uniprot id: A0A803VXK3
uniprot id: A0A803WEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

59894:PTCD3
gene id: 59894:PTCD3
uniprot id: A0A803V866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

59894:THSD1
gene id: 59894:THSD1
uniprot id: U3K1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plasmodium circumsporozoite protein family.
messages: Cell membrane
messages: Cytoplasm
messages: In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
messages: Membrane

59894:PRKAA1
gene id: 59894:PRKAA1
uniprot id: U3JH39
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

59894:PTPRE
gene id: 59894:PTPRE
uniprot id: A0A803VH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

59894:TRAK2
gene id: 59894:TRAK2
uniprot id: A0A803VNJ0
uniprot id: U3JND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

59894:RAB38
gene id: 59894:RAB38
uniprot id: U3JZI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

59894:SLC25A36
gene id: 59894:SLC25A36
uniprot id: U3JW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:CD28
gene id: 59894:CD28
uniprot id: U3JM69
names: Subcellular Location Annotation
messages: Membrane

59894:OPN5
gene id: 59894:OPN5
uniprot id: U3JFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

59894:FUT7
gene id: 59894:FUT7
uniprot id: U3KJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

59894:C17H9orf78
gene id: 59894:C17H9orf78
uniprot id: U3JFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

59894:RNF152
gene id: 59894:RNF152
uniprot id: U3KK12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

59894:GDF9
gene id: 59894:GDF9
uniprot id: A0A803V0Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

59894:NUDCD1
gene id: 59894:NUDCD1
uniprot id: A0A803WAN5
uniprot id: U3JUC9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:ZCCHC11
gene id: 59894:ZCCHC11
uniprot id: A0A803VP66
uniprot id: A0A803VQB9
uniprot id: A0A803VUM2
uniprot id: U3JST8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

59894:DMGDH
gene id: 59894:DMGDH
uniprot id: U3K5S2
names: Similarity
messages: Belongs to the GcvT family.

59894:PSMD12
gene id: 59894:PSMD12
uniprot id: U3JI97
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

59894:SLC30A4
gene id: 59894:SLC30A4
uniprot id: U3KAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

59894:SH3RF1
gene id: 59894:SH3RF1
uniprot id: U3KA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

59894:TSR1
gene id: 59894:TSR1
uniprot id: U3JVK7
names: Subcellular Location Annotation
messages: nucleolus

59894:CHSY1
gene id: 59894:CHSY1
uniprot id: U3K6J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

59894:SPPL3
gene id: 59894:SPPL3
uniprot id: A0A803WB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

59894:ANAPC10
gene id: 59894:ANAPC10
uniprot id: U3JSL0
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

59894:CELF6
gene id: 59894:CELF6
uniprot id: U3K4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

59894:KIF21A
gene id: 59894:KIF21A
uniprot id: A0A803VKH5
uniprot id: A0A803VS61
uniprot id: A0A803W1V0
uniprot id: A0A803W388
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:SFXN1
gene id: 59894:SFXN1
uniprot id: A0A803VZ39
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

59894:EIF5A2
gene id: 59894:EIF5A2
uniprot id: U3K1P3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

59894:GABRD
gene id: 59894:GABRD
uniprot id: U3K4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:NAP1L4
gene id: 59894:NAP1L4
uniprot id: U3KA74
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

59894:IL15RA
gene id: 59894:IL15RA
uniprot id: U3JRG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ERBB2
gene id: 59894:ERBB2
uniprot id: U3JCP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

59894:ST6GALNAC2
gene id: 59894:ST6GALNAC2
uniprot id: U3JDV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:CLRN1
gene id: 59894:CLRN1
uniprot id: U3JRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

59894:TBPL1
gene id: 59894:TBPL1
uniprot id: U3KBI6
names: Similarity
messages: Belongs to the TBP family.

59894:ROPN1L
gene id: 59894:ROPN1L
uniprot id: A0A803V6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

59894:SLC52A3
gene id: 59894:SLC52A3
uniprot id: U3JT59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

59894:SEMA3C
gene id: 59894:SEMA3C
uniprot id: A0A803V955
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:FMN1
gene id: 59894:FMN1
uniprot id: A0A803W6Y9
uniprot id: U3JSS5
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

59894:TMEM59L
gene id: 59894:TMEM59L
uniprot id: U3K444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:LOC101808840
gene id: 59894:LOC101808840
uniprot id: U3KKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:CCDC109B
gene id: 59894:CCDC109B
uniprot id: A0A803VT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Membrane
messages: Mitochondrion inner membrane

59894:SLC16A3
gene id: 59894:SLC16A3
uniprot id: A0A803V0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

59894:LOC101818893
gene id: 59894:LOC101818893
uniprot id: U3KIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

59894:CHRNA1
gene id: 59894:CHRNA1
uniprot id: A0A803VYE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:GRPR
gene id: 59894:GRPR
uniprot id: U3JP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:UROD
gene id: 59894:UROD
uniprot id: U3JR91
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

59894:PRRX1
gene id: 59894:PRRX1
uniprot id: U3JZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

59894:SVIL
gene id: 59894:SVIL
uniprot id: A0A803W1S9
names: Similarity
messages: Belongs to the villin/gelsolin family.

59894:VIPAS39
gene id: 59894:VIPAS39
uniprot id: U3KDY1
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Late endosome

59894:BRCA1
gene id: 59894:BRCA1
uniprot id: U3JDH4
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm
messages: Nucleus

59894:METTL14
gene id: 59894:METTL14
uniprot id: U3JHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with mettl3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.

59894:LOC101820645
gene id: 59894:LOC101820645
uniprot id: A0A803V285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

59894:GADD45G
gene id: 59894:GADD45G
uniprot id: A0A803W089
names: Similarity
messages: Belongs to the GADD45 family.

59894:RSAD1
gene id: 59894:RSAD1
uniprot id: A0A803W937
uniprot id: U3JF25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

59894:CDK8
gene id: 59894:CDK8
uniprot id: A0A803VVQ2
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:USP37
gene id: 59894:USP37
uniprot id: U3JN86
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:TXNRD3
gene id: 59894:TXNRD3
uniprot id: U3JZI1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

59894:MGAT5B
gene id: 59894:MGAT5B
uniprot id: U3JDN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:LOC101813216
gene id: 59894:LOC101813216
uniprot id: A0A803WD27
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:AP1M1
gene id: 59894:AP1M1
uniprot id: A0A803VT56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

59894:ETFDH
gene id: 59894:ETFDH
uniprot id: U3JK69
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

59894:GPR15
gene id: 59894:GPR15
uniprot id: U3KIE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:MIEF2
gene id: 59894:MIEF2
uniprot id: U3KH15
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

59894:LOC101815406
gene id: 59894:LOC101815406
uniprot id: U3KFI5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

59894:LOC101816129
gene id: 59894:LOC101816129
uniprot id: A0A803VHI2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

59894:USP16
gene id: 59894:USP16
uniprot id: U3JUZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Homotetramer.
messages: Nucleus
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

59894:C25H1orf43
gene id: 59894:C25H1orf43
uniprot id: U3JEM4
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

59894:MFSD9
gene id: 59894:MFSD9
uniprot id: A0A803V8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

59894:GTF2A2
gene id: 59894:GTF2A2
uniprot id: U3KDJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

59894:LOC101809834
gene id: 59894:LOC101809834
uniprot id: U3JC04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

59894:RRAGC
gene id: 59894:RRAGC
uniprot id: U3JE78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

59894:CYFIP2
gene id: 59894:CYFIP2
uniprot id: A0A803VE00
uniprot id: U3K162
names: Similarity
messages: Belongs to the CYFIP family.

59894:LOC101820237
gene id: 59894:LOC101820237
uniprot id: A0A803VSG2
names: Subcellular Location Annotation
messages: Nucleus

59894:STOM
gene id: 59894:STOM
uniprot id: U3JGR8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

59894:RTN4
gene id: 59894:RTN4
uniprot id: A0A803V3R4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:PVALB
gene id: 59894:PVALB
uniprot id: A0A803W413
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

59894:IP6K2
gene id: 59894:IP6K2
uniprot id: U3K0U8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

59894:RBP1
gene id: 59894:RBP1
uniprot id: U3JNC4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:ZCCHC6
gene id: 59894:ZCCHC6
uniprot id: U3JLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

59894:ORAI1
gene id: 59894:ORAI1
uniprot id: A0A803V3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

59894:CASC1
gene id: 59894:CASC1
uniprot id: A0A803VM62
names: Similarity
messages: Belongs to the DNAI7 family.

59894:MSH6
gene id: 59894:MSH6
uniprot id: U3K9A9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

59894:ERGIC3
gene id: 59894:ERGIC3
uniprot id: U3KDG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

59894:DPYSL2
gene id: 59894:DPYSL2
uniprot id: U3K9V5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

59894:DNAL4
gene id: 59894:DNAL4
uniprot id: U3KD54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

59894:CACNG3
gene id: 59894:CACNG3
uniprot id: A0A803W6Q6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:MICAL1
gene id: 59894:MICAL1
uniprot id: U3JM18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

59894:GALNT16
gene id: 59894:GALNT16
uniprot id: A0A803W8W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

59894:PRPS1
gene id: 59894:PRPS1
uniprot id: U3K9R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

59894:C2H8orf22
gene id: 59894:C2H8orf22
uniprot id: U3JT93
names: Similarity
messages: Belongs to the PPDPF family.

59894:PBRM1
gene id: 59894:PBRM1
uniprot id: A0A803V2U9
uniprot id: A0A803V958
uniprot id: A0A803V9J1
names: Subcellular Location Annotation
messages: Nucleus

59894:IRX1
gene id: 59894:IRX1
uniprot id: U3JRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

59894:LOC101808127
gene id: 59894:LOC101808127
uniprot id: U3JMF5
names: Subcellular Location Annotation
messages: acrosome

59894:ND5
gene id: 59894:ND5
uniprot id: S0AU87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

59894:LOC101808989
gene id: 59894:LOC101808989
uniprot id: U3K401
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:PHYKPL
gene id: 59894:PHYKPL
uniprot id: U3JYY7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

59894:TACR2
gene id: 59894:TACR2
uniprot id: U3KFB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:PKP1
gene id: 59894:PKP1
uniprot id: A0A803V103
names: Similarity
messages: Belongs to the beta-catenin family.

59894:CACNA2D4
gene id: 59894:CACNA2D4
uniprot id: U3JKY1
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

59894:LOC101821004
gene id: 59894:LOC101821004
uniprot id: U3JYQ1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

59894:ATXN3
gene id: 59894:ATXN3
uniprot id: A0A803V3Z4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

59894:TPST2
gene id: 59894:TPST2
uniprot id: U3K1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

59894:CHDH
gene id: 59894:CHDH
uniprot id: U3K1Q0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

59894:BRINP3
gene id: 59894:BRINP3
uniprot id: U3JL82
names: Similarity
messages: Belongs to the BRINP family.

59894:GFOD2
gene id: 59894:GFOD2
uniprot id: U3JWV2
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

59894:TRAF5
gene id: 59894:TRAF5
uniprot id: U3KDG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

59894:NRG4
gene id: 59894:NRG4
uniprot id: U3K818
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101822186
gene id: 59894:LOC101822186
uniprot id: U3K9E5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

59894:CHPT1
gene id: 59894:CHPT1
uniprot id: U3K358
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

59894:LOC101809980
gene id: 59894:LOC101809980
uniprot id: U3JIK3
names: Similarity
messages: Belongs to the serpin family.

59894:TCEA3
gene id: 59894:TCEA3
uniprot id: A0A803V5X8
uniprot id: A0A803V9X3
uniprot id: U3K866
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

59894:CDH7
gene id: 59894:CDH7
uniprot id: U3JVM3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:RPS21
gene id: 59894:RPS21
uniprot id: U3K7K9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

59894:LOC101810615
gene id: 59894:LOC101810615
uniprot id: A0A803VCK6
names: Subcellular Location Annotation
messages: Membrane

59894:DDX59
gene id: 59894:DDX59
uniprot id: U3JJ61
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

59894:TBX15
gene id: 59894:TBX15
uniprot id: U3JR47
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

59894:LOC101820878
gene id: 59894:LOC101820878
uniprot id: A0A803VSA6
uniprot id: U3K2Z5
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

59894:KCNG4
gene id: 59894:KCNG4
uniprot id: U3JW55
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101818606
gene id: 59894:LOC101818606
uniprot id: U3JZ50
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

59894:EIF2S1
gene id: 59894:EIF2S1
uniprot id: A0A803W166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

59894:PIGN
gene id: 59894:PIGN
uniprot id: A0A803WA42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

59894:LOC101810531
gene id: 59894:LOC101810531
uniprot id: U3KKS0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:GCK
gene id: 59894:GCK
uniprot id: U3JBB1
names: Similarity
messages: Belongs to the hexokinase family.

59894:LOC101821531
gene id: 59894:LOC101821531
uniprot id: U3JYX5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

59894:CORO1C
gene id: 59894:CORO1C
uniprot id: U3K2J6
names: Similarity
messages: Belongs to the WD repeat coronin family.

59894:LOC101812163
gene id: 59894:LOC101812163
uniprot id: U3KBU3
names: Subcellular Location Annotation
messages: Membrane

59894:NUTF2
gene id: 59894:NUTF2
uniprot id: A0A803W1L4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

59894:MDGA1
gene id: 59894:MDGA1
uniprot id: U3K9L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:LOC101810563
gene id: 59894:LOC101810563
uniprot id: U3KIQ1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

59894:GRHL2
gene id: 59894:GRHL2
uniprot id: A0A803VEH2
names: Subcellular Location Annotation
messages: Nucleus

59894:SERPINC1
gene id: 59894:SERPINC1
uniprot id: U3JJZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: extracellular space

59894:THNSL1
gene id: 59894:THNSL1
uniprot id: U3KK25
names: Similarity
messages: Belongs to the threonine synthase family.

59894:LOC101807262
gene id: 59894:LOC101807262
uniprot id: A0A803VPD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

59894:APOH
gene id: 59894:APOH
uniprot id: U3JIA9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:FAHD1
gene id: 59894:FAHD1
uniprot id: U3KJQ1
names: Similarity
messages: Belongs to the FAH family.

59894:TES
gene id: 59894:TES
uniprot id: U3K6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

59894:CLDN3
gene id: 59894:CLDN3
uniprot id: U3KIP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:SORD
gene id: 59894:SORD
uniprot id: U3K5G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Mitochondrion membrane
messages: flagellum

59894:FICD
gene id: 59894:FICD
uniprot id: U3K2P1
names: Similarity
messages: Belongs to the fic family.

59894:MED1
gene id: 59894:MED1
uniprot id: U3JCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

59894:KCNJ15
gene id: 59894:KCNJ15
uniprot id: A0A803VE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

59894:FAM214B
gene id: 59894:FAM214B
uniprot id: A0A803W1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

59894:MC2R
gene id: 59894:MC2R
uniprot id: U3KIH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

59894:NMNAT3
gene id: 59894:NMNAT3
uniprot id: A0A803V3H8
uniprot id: A0A803VPE5
uniprot id: A0A803VUC4
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

59894:LOC101807260
gene id: 59894:LOC101807260
uniprot id: U3JZI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:FARS2
gene id: 59894:FARS2
uniprot id: U3KFE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

59894:USO1
gene id: 59894:USO1
uniprot id: A0A803VSK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

59894:KMT5B
gene id: 59894:KMT5B
uniprot id: A0A803V032
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

59894:HMBS
gene id: 59894:HMBS
uniprot id: U3K5C2
names: Similarity
messages: Belongs to the HMBS family.

59894:CLCN3
gene id: 59894:CLCN3
uniprot id: A0A803VFZ9
uniprot id: A0A803VPK3
uniprot id: U3KA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

59894:DPH5
gene id: 59894:DPH5
uniprot id: U3JIG1
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

59894:MGME1
gene id: 59894:MGME1
uniprot id: U3JYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair.
messages: Mitochondrion

59894:OTX1
gene id: 59894:OTX1
uniprot id: U3KGN1
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101817098
gene id: 59894:LOC101817098
uniprot id: A0A803VH40
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:RPL34
gene id: 59894:RPL34
uniprot id: U3KCM4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

59894:SULT4A1
gene id: 59894:SULT4A1
uniprot id: U3JVY2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:PFKFB3
gene id: 59894:PFKFB3
uniprot id: A0A803V952
uniprot id: U3JGG0
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

59894:TAF1B
gene id: 59894:TAF1B
uniprot id: U3JVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

59894:TSPAN1
gene id: 59894:TSPAN1
uniprot id: U3K4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:RPS6
gene id: 59894:RPS6
uniprot id: U3JK94
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

59894:CNKSR2
gene id: 59894:CNKSR2
uniprot id: A0A803VLR8
names: Similarity
messages: Belongs to the CNKSR family.

59894:ST3GAL5
gene id: 59894:ST3GAL5
uniprot id: U3K656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:LOC101807492
gene id: 59894:LOC101807492
uniprot id: A0A803VN62
uniprot id: U3KBD3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

59894:MRPL46
gene id: 59894:MRPL46
uniprot id: U3K777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

59894:KCNT1
gene id: 59894:KCNT1
uniprot id: U3JGF9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:JUN
gene id: 59894:JUN
uniprot id: U3KL25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

59894:RABEP1
gene id: 59894:RABEP1
uniprot id: U3K587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

59894:C2H6orf52
gene id: 59894:C2H6orf52
uniprot id: A0A803VCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

59894:GHR
gene id: 59894:GHR
uniprot id: A0A803VXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Cell membrane
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

59894:NDEL1
gene id: 59894:NDEL1
uniprot id: A0A803VMI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

59894:MKX
gene id: 59894:MKX
uniprot id: U3JXF9
names: Subcellular Location Annotation
messages: Nucleus

59894:SSTR5
gene id: 59894:SSTR5
uniprot id: U3KIC6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:PDIA6
gene id: 59894:PDIA6
uniprot id: A0A803VCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

59894:F2
gene id: 59894:F2
uniprot id: A0A803VHB2
uniprot id: U3JUU7
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

59894:AURKA
gene id: 59894:AURKA
uniprot id: U3K8Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

59894:PPP2R2C
gene id: 59894:PPP2R2C
uniprot id: A0A803V4G1
uniprot id: A0A803VVL7
uniprot id: U3K4T1
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

59894:FAM45A
gene id: 59894:FAM45A
uniprot id: U3JHM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

59894:NDUFV3
gene id: 59894:NDUFV3
uniprot id: U3JGZ6
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

59894:MRPS14
gene id: 59894:MRPS14
uniprot id: U3K160
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

59894:NUP50
gene id: 59894:NUP50
uniprot id: A0A803VXZ9
names: Subcellular Location Annotation
messages: nuclear pore complex

59894:FOXN3
gene id: 59894:FOXN3
uniprot id: A0A803W7A1
uniprot id: U3KCX1
names: Function
names: Subcellular Location Annotation
messages: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
messages: Nucleus

59894:IPO11
gene id: 59894:IPO11
uniprot id: U3K964
names: Subcellular Location Annotation
messages: Cytoplasm

59894:STAMBPL1
gene id: 59894:STAMBPL1
uniprot id: U3JYY2
names: Similarity
messages: Belongs to the peptidase M67C family.

59894:SSU72
gene id: 59894:SSU72
uniprot id: U3K406
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

59894:HN1
gene id: 59894:HN1
uniprot id: U3JES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

59894:NRXN1
gene id: 59894:NRXN1
uniprot id: A0A803V6H6
names: Subcellular Location Annotation
messages: Membrane

59894:TDRD9
gene id: 59894:TDRD9
uniprot id: U3JJT2
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

59894:TNRC6C
gene id: 59894:TNRC6C
uniprot id: A0A803VZZ9
names: Similarity
messages: Belongs to the GW182 family.

59894:GINS4
gene id: 59894:GINS4
uniprot id: A0A803WC57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

59894:PTPN21
gene id: 59894:PTPN21
uniprot id: A0A803VZ32
uniprot id: U3KD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

59894:TMEM19
gene id: 59894:TMEM19
uniprot id: U3K6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

59894:JAK2
gene id: 59894:JAK2
uniprot id: U3K7L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

59894:GPM6B
gene id: 59894:GPM6B
uniprot id: A0A803V6I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

59894:MPP6
gene id: 59894:MPP6
uniprot id: A0A803WBA7
uniprot id: U3K4M1
names: Similarity
messages: Belongs to the MAGUK family.

59894:CSNK2A1
gene id: 59894:CSNK2A1
uniprot id: U3JT45
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:GRHL3
gene id: 59894:GRHL3
uniprot id: U3JCK5
names: Subcellular Location Annotation
messages: Nucleus

59894:RGS9
gene id: 59894:RGS9
uniprot id: U3JIE6
names: Subcellular Location Annotation
messages: Membrane

59894:ATP6V1E1
gene id: 59894:ATP6V1E1
uniprot id: A0A803V0H7
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

59894:PRKCA
gene id: 59894:PRKCA
uniprot id: A0A803V4T5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

59894:PSAT1
gene id: 59894:PSAT1
uniprot id: A0A803VPU4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

59894:TMEM45B
gene id: 59894:TMEM45B
uniprot id: U3JQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

59894:ACE2
gene id: 59894:ACE2
uniprot id: U3JP73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

59894:DDX1
gene id: 59894:DDX1
uniprot id: U3K215
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

59894:NGLY1
gene id: 59894:NGLY1
uniprot id: U3K3H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

59894:GMPPA
gene id: 59894:GMPPA
uniprot id: A0A803VVI1
uniprot id: U3JNW3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

59894:PLXNA4
gene id: 59894:PLXNA4
uniprot id: A0A803VY74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:KIF16B
gene id: 59894:KIF16B
uniprot id: A0A803VDS7
uniprot id: A0A803VSD9
uniprot id: A0A803W4G4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:SPNS3
gene id: 59894:SPNS3
uniprot id: U3JXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

59894:TSPOAP1
gene id: 59894:TSPOAP1
uniprot id: A0A803VNS4
uniprot id: U3KH51
names: Similarity
messages: Belongs to the RIMBP family.

59894:FGD5
gene id: 59894:FGD5
uniprot id: U3KGX9
names: Subcellular Location Annotation
messages: cytoskeleton

59894:GPR182
gene id: 59894:GPR182
uniprot id: U3KIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:ZDHHC20
gene id: 59894:ZDHHC20
uniprot id: U3K239
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:CLK4
gene id: 59894:CLK4
uniprot id: U3JZ10
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:MYH11
gene id: 59894:MYH11
uniprot id: A0A803VQH0
uniprot id: U3KI15
uniprot id: U3KI16
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

59894:RPSA
gene id: 59894:RPSA
uniprot id: U3KD08
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

59894:ARGLU1
gene id: 59894:ARGLU1
uniprot id: A0A803WDG0
names: Similarity
messages: Belongs to the UPF0430 family.

59894:ZDHHC13
gene id: 59894:ZDHHC13
uniprot id: U3JFX9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:SLC37A1
gene id: 59894:SLC37A1
uniprot id: U3JGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

59894:ALG6
gene id: 59894:ALG6
uniprot id: U3KDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:OC90
gene id: 59894:OC90
uniprot id: U3JIV0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

59894:SH3BP5
gene id: 59894:SH3BP5
uniprot id: U3K382
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

59894:CHRM5
gene id: 59894:CHRM5
uniprot id: U3KL95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

59894:STRIP2
gene id: 59894:STRIP2
uniprot id: U3JQU0
names: Similarity
messages: Belongs to the STRIP family.

59894:SCD
gene id: 59894:SCD
uniprot id: U3JY31
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

59894:VGLL4
gene id: 59894:VGLL4
uniprot id: A0A803WAQ9
uniprot id: U3JB54
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

59894:CA9
gene id: 59894:CA9
uniprot id: U3JHK9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

59894:QRFPR
gene id: 59894:QRFPR
uniprot id: U3K104
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:VAC14
gene id: 59894:VAC14
uniprot id: U3JY28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

59894:LOC101814966
gene id: 59894:LOC101814966
uniprot id: U3K717
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:PDGFC
gene id: 59894:PDGFC
uniprot id: U3JKC5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CDR2
gene id: 59894:CDR2
uniprot id: U3KHV4
names: Similarity
messages: Belongs to the CDR2 family.

59894:STRADB
gene id: 59894:STRADB
uniprot id: U3JND4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

59894:AMBP
gene id: 59894:AMBP
uniprot id: A0A803WCP2
names: Similarity
names: Subcellular Location Annotation
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

59894:LOC101817527
gene id: 59894:LOC101817527
uniprot id: U3JNQ8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:FIGNL1
gene id: 59894:FIGNL1
uniprot id: U3KKF8
names: Similarity
messages: Belongs to the AAA ATPase family.

59894:KPNA1
gene id: 59894:KPNA1
uniprot id: U3JQT0
uniprot id: U3JQT2
names: Similarity
messages: Belongs to the importin alpha family.

59894:AXIN1
gene id: 59894:AXIN1
uniprot id: U3JND6
names: Subcellular Location Annotation
messages: Cytoplasm

59894:LOC101809392
gene id: 59894:LOC101809392
uniprot id: A0A803VHN6
names: Subcellular Location Annotation
messages: Nucleus

59894:HDAC8
gene id: 59894:HDAC8
uniprot id: U3KBX2
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.

59894:LOC101813957
gene id: 59894:LOC101813957
uniprot id: U3KLL0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:BCO2
gene id: 59894:BCO2
uniprot id: U3JUM2
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

59894:IL15
gene id: 59894:IL15
uniprot id: A0A803VDK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

59894:GPR26
gene id: 59894:GPR26
uniprot id: U3JQ74
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:CTPS2
gene id: 59894:CTPS2
uniprot id: U3JP35
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

59894:TAC1
gene id: 59894:TAC1
uniprot id: A0A803W7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

59894:CRCP
gene id: 59894:CRCP
uniprot id: A0A803VSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

59894:OTOP3
gene id: 59894:OTOP3
uniprot id: U3JEU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

59894:LOC101815012
gene id: 59894:LOC101815012
uniprot id: A0A803V8I0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:NSMCE4A
gene id: 59894:NSMCE4A
uniprot id: A0A803V3Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

59894:PSKH1
gene id: 59894:PSKH1
uniprot id: U3JX63
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:ANO6
gene id: 59894:ANO6
uniprot id: U3K6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

59894:LOC101809344
gene id: 59894:LOC101809344
uniprot id: U3JKH2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:NOS2
gene id: 59894:NOS2
uniprot id: U3JQR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

59894:DCK
gene id: 59894:DCK
uniprot id: A0A803W661
names: Similarity
messages: Belongs to the DCK/DGK family.

59894:EPHA4
gene id: 59894:EPHA4
uniprot id: U3JW50
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

59894:STEAP4
gene id: 59894:STEAP4
uniprot id: U3JZM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

59894:CENPH
gene id: 59894:CENPH
uniprot id: U3K5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

59894:ST7
gene id: 59894:ST7
uniprot id: A0A803W1K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

59894:GRB10
gene id: 59894:GRB10
uniprot id: A0A803W7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

59894:KIAA1147
gene id: 59894:KIAA1147
uniprot id: U3JME4
names: Similarity
messages: Belongs to the DENND11 family.

59894:SLC6A19
gene id: 59894:SLC6A19
uniprot id: A0A803W386
uniprot id: U3JHH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:PPP2R4
gene id: 59894:PPP2R4
uniprot id: U3JFD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

59894:PUS1
gene id: 59894:PUS1
uniprot id: A0A803VIQ1
uniprot id: A0A803W6P7
uniprot id: U3K0R6
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

59894:SMIM8
gene id: 59894:SMIM8
uniprot id: U3JJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

59894:FASLG
gene id: 59894:FASLG
uniprot id: A0A803VWN3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

59894:PPM1A
gene id: 59894:PPM1A
uniprot id: A0A803VYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

59894:MAP2
gene id: 59894:MAP2
uniprot id: A0A803VCR2
uniprot id: A0A803VKR6
uniprot id: A0A803VZZ3
uniprot id: A0A803W4F6
names: Subcellular Location Annotation
messages: cytoskeleton

59894:RAD18
gene id: 59894:RAD18
uniprot id: U3KGR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

59894:ELAVL1
gene id: 59894:ELAVL1
uniprot id: U3KB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

59894:LOC101820004
gene id: 59894:LOC101820004
uniprot id: A0A803W8R7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

59894:PIGX
gene id: 59894:PIGX
uniprot id: U3JKC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

59894:SOSTDC1
gene id: 59894:SOSTDC1
uniprot id: U3K5U4
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ACTC1
gene id: 59894:ACTC1
uniprot id: U3JT25
names: Similarity
messages: Belongs to the actin family.

59894:NDUFS8
gene id: 59894:NDUFS8
uniprot id: A0A803VQ51
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

59894:RPS14
gene id: 59894:RPS14
uniprot id: A0A803VYV8
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

59894:LOC101815725
gene id: 59894:LOC101815725
uniprot id: U3JZ37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

59894:FAM114A1
gene id: 59894:FAM114A1
uniprot id: U3K3W7
names: Similarity
messages: Belongs to the FAM114 family.

59894:SMARCD3
gene id: 59894:SMARCD3
uniprot id: A0A803WEN8
names: Similarity
messages: Belongs to the SMARCD family.

59894:LOC101809314
gene id: 59894:LOC101809314
uniprot id: A0A803VZ27
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

59894:LOC101808006
gene id: 59894:LOC101808006
uniprot id: U3KKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:SLC13A3
gene id: 59894:SLC13A3
uniprot id: U3JRG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

59894:PRKG1
gene id: 59894:PRKG1
uniprot id: A0A803WF94
uniprot id: U3KFF9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

59894:LOC101810239
gene id: 59894:LOC101810239
uniprot id: U3JHT2
names: Subcellular Location Annotation
messages: Secreted

59894:TMEM8B
gene id: 59894:TMEM8B
uniprot id: U3JBK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

59894:UNC13B
gene id: 59894:UNC13B
uniprot id: A0A803V064
uniprot id: U3K548
names: Subcellular Location Annotation
messages: Cytoplasm

59894:USE1
gene id: 59894:USE1
uniprot id: A0A803W1W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:WISP1
gene id: 59894:WISP1
uniprot id: A0A803W3V5
uniprot id: U3JJ81
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:EIF2B1
gene id: 59894:EIF2B1
uniprot id: A0A803WAZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

59894:GPR137B
gene id: 59894:GPR137B
uniprot id: U3KGD3
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

59894:TMEM97
gene id: 59894:TMEM97
uniprot id: A0A803WAS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

59894:CUEDC2
gene id: 59894:CUEDC2
uniprot id: A0A803VNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

59894:PAFAH1B1
gene id: 59894:PAFAH1B1
uniprot id: U3JQ84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

59894:FAM103A1
gene id: 59894:FAM103A1
uniprot id: A0A803VRE7
uniprot id: U3K9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

59894:LOC101818422
gene id: 59894:LOC101818422
uniprot id: U3JTE6
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

59894:RALY
gene id: 59894:RALY
uniprot id: A0A803VU39
uniprot id: A0A803WGU9
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

59894:CDC25A
gene id: 59894:CDC25A
uniprot id: U3JH16
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

59894:P4HA2
gene id: 59894:P4HA2
uniprot id: A0A803VQQ2
uniprot id: U3JEE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

59894:ST8SIA4
gene id: 59894:ST8SIA4
uniprot id: U3JJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:SNED1
gene id: 59894:SNED1
uniprot id: U3JLH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:BMPR1B
gene id: 59894:BMPR1B
uniprot id: U3JUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

59894:SFXN3
gene id: 59894:SFXN3
uniprot id: U3K1Y6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

59894:GPRIN3
gene id: 59894:GPRIN3
uniprot id: U3KKA8
names: Function
messages: May be involved in neurite outgrowth.

59894:B3GAT1
gene id: 59894:B3GAT1
uniprot id: A0A803V1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:WFIKKN2
gene id: 59894:WFIKKN2
uniprot id: A0A803VPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Secreted

59894:CDCA7
gene id: 59894:CDCA7
uniprot id: U3JJT6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:LOC101817428
gene id: 59894:LOC101817428
uniprot id: U3JV33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

59894:ZFYVE16
gene id: 59894:ZFYVE16
uniprot id: U3KEF3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

59894:LCA5L
gene id: 59894:LCA5L
uniprot id: U3JR11
names: Similarity
messages: Belongs to the LCA5 family.

59894:CENPU
gene id: 59894:CENPU
uniprot id: A0A803UZY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

59894:LPL
gene id: 59894:LPL
uniprot id: U3JR81
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

59894:FOXN2
gene id: 59894:FOXN2
uniprot id: A0A803V0J5
names: Subcellular Location Annotation
messages: Nucleus

59894:TMEM135
gene id: 59894:TMEM135
uniprot id: U3JZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

59894:MTTP
gene id: 59894:MTTP
uniprot id: U3JUR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ADGRL2
gene id: 59894:ADGRL2
uniprot id: A0A803VFA0
names: Subcellular Location Annotation
messages: Membrane

59894:ZER1
gene id: 59894:ZER1
uniprot id: A0A803V0G0
names: Similarity
messages: Belongs to the zyg-11 family.

59894:SLC27A6
gene id: 59894:SLC27A6
uniprot id: U3JQP0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

59894:FAM160B1
gene id: 59894:FAM160B1
uniprot id: U3JHR8
names: Similarity
messages: Belongs to the FHIP family.

59894:C7
gene id: 59894:C7
uniprot id: U3JH31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:SLC25A22
gene id: 59894:SLC25A22
uniprot id: U3K7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:CLDN25
gene id: 59894:CLDN25
uniprot id: U3KJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:ZC3H14
gene id: 59894:ZC3H14
uniprot id: A0A803V317
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

59894:LOC101812686
gene id: 59894:LOC101812686
uniprot id: U3JQZ5
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:IST1
gene id: 59894:IST1
uniprot id: U3JIY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

59894:KCNE2
gene id: 59894:KCNE2
uniprot id: U3KI99
names: Similarity
messages: Belongs to the potassium channel KCNE family.

59894:SYK
gene id: 59894:SYK
uniprot id: U3JQ94
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

59894:SULF2
gene id: 59894:SULF2
uniprot id: A0A803V5V4
uniprot id: A0A803VGN4
uniprot id: U3KEL7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

59894:TMEM63B
gene id: 59894:TMEM63B
uniprot id: A0A803WGK1
uniprot id: U3K9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

59894:LOC101817587
gene id: 59894:LOC101817587
uniprot id: U3KIU4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:GPD1L
gene id: 59894:GPD1L
uniprot id: A0A803W2P1
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

59894:PSPH
gene id: 59894:PSPH
uniprot id: U3JWC0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

59894:OTULIN
gene id: 59894:OTULIN
uniprot id: U3JYF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

59894:HNRNPA3
gene id: 59894:HNRNPA3
uniprot id: A0A803WG68
names: Subcellular Location Annotation
messages: Nucleus

59894:ACY1
gene id: 59894:ACY1
uniprot id: U3K2G7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm

59894:MED13
gene id: 59894:MED13
uniprot id: U3JSI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

59894:GLMP
gene id: 59894:GLMP
uniprot id: U3JNQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLMP family.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

59894:PTGS1
gene id: 59894:PTGS1
uniprot id: U3JH32
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:STK32C
gene id: 59894:STK32C
uniprot id: A0A803VKV5
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:CALHM1
gene id: 59894:CALHM1
uniprot id: U3K2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

59894:FANCC
gene id: 59894:FANCC
uniprot id: U3JLK4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

59894:TIMM9
gene id: 59894:TIMM9
uniprot id: A0A803VUY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

59894:NTF3
gene id: 59894:NTF3
uniprot id: U3JVR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

59894:SMPD2
gene id: 59894:SMPD2
uniprot id: U3JLY9
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

59894:SLC29A3
gene id: 59894:SLC29A3
uniprot id: U3KG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

59894:S1PR1
gene id: 59894:S1PR1
uniprot id: U3KJ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:HGFAC
gene id: 59894:HGFAC
uniprot id: U3K538
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:NXPH2
gene id: 59894:NXPH2
uniprot id: U3KI60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

59894:ETV6
gene id: 59894:ETV6
uniprot id: U3JIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:GNB4
gene id: 59894:GNB4
uniprot id: U3K127
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

59894:TMEM177
gene id: 59894:TMEM177
uniprot id: U3KI53
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

59894:TSPAN3
gene id: 59894:TSPAN3
uniprot id: A0A803WF08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:TRAPPC4
gene id: 59894:TRAPPC4
uniprot id: A0A803VVJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

59894:GAL3ST1
gene id: 59894:GAL3ST1
uniprot id: A0A803VAE9
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

59894:USP5
gene id: 59894:USP5
uniprot id: U3JQ23
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:RPTOR
gene id: 59894:RPTOR
uniprot id: A0A803VHD1
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

59894:LOC101809643
gene id: 59894:LOC101809643
uniprot id: U3JU74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

59894:SLC16A14
gene id: 59894:SLC16A14
uniprot id: U3JWW8
names: Subcellular Location Annotation
messages: Membrane

59894:TPT1
gene id: 59894:TPT1
uniprot id: U3K0H1
names: Similarity
messages: Belongs to the TCTP family.

59894:PM20D2
gene id: 59894:PM20D2
uniprot id: U3JJZ8
names: Similarity
messages: Belongs to the peptidase M20A family.

59894:LOC101816626
gene id: 59894:LOC101816626
uniprot id: A0A803V5Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

59894:CCDC126
gene id: 59894:CCDC126
uniprot id: U3K4Q2
names: Subcellular Location Annotation
messages: Secreted

59894:EAF2
gene id: 59894:EAF2
uniprot id: U3KFP4
names: Similarity
messages: Belongs to the EAF family.

59894:DIS3L
gene id: 59894:DIS3L
uniprot id: U3K610
names: Similarity
messages: Belongs to the RNR ribonuclease family.

59894:MOGAT2
gene id: 59894:MOGAT2
uniprot id: U3KBP2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ADAMTS19
gene id: 59894:ADAMTS19
uniprot id: U3JQM0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

59894:NLGN3
gene id: 59894:NLGN3
uniprot id: A0A803V1H4
uniprot id: A0A803VPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

59894:CAPN2
gene id: 59894:CAPN2
uniprot id: U3KBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

59894:AMPD3
gene id: 59894:AMPD3
uniprot id: A0A803VKH8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

59894:ATP8
gene id: 59894:ATP8
uniprot id: S0ARW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase protein 8 family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Membrane
messages: Mitochondrion membrane

59894:ELAVL4
gene id: 59894:ELAVL4
uniprot id: A0A803VB94
uniprot id: A0A803VK91
uniprot id: A0A803VNT0
uniprot id: A0A803W3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

59894:PMEPA1
gene id: 59894:PMEPA1
uniprot id: A0A803VN90
uniprot id: A0A803W5D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

59894:GSTZ1
gene id: 59894:GSTZ1
uniprot id: U3KE46
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

59894:CYLD
gene id: 59894:CYLD
uniprot id: A0A803WEP9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

59894:KCNG3
gene id: 59894:KCNG3
uniprot id: U3KDS9
names: Subcellular Location Annotation
messages: Membrane

59894:CGA
gene id: 59894:CGA
uniprot id: U3JJS4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

59894:LOC101812532
gene id: 59894:LOC101812532
uniprot id: A0A803VAC1
names: Subcellular Location Annotation
messages: Membrane

59894:SPSB1
gene id: 59894:SPSB1
uniprot id: U3JY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

59894:NR2C2
gene id: 59894:NR2C2
uniprot id: U3KGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:PELI2
gene id: 59894:PELI2
uniprot id: A0A803VVS7
uniprot id: U3JM71
names: Similarity
messages: Belongs to the pellino family.

59894:CUL5
gene id: 59894:CUL5
uniprot id: A0A803W4G6
names: Similarity
messages: Belongs to the cullin family.

59894:GSKIP
gene id: 59894:GSKIP
uniprot id: U3JIP0
names: Similarity
messages: Belongs to the GSKIP family.

59894:LCA5
gene id: 59894:LCA5
uniprot id: U3JJ15
names: Similarity
messages: Belongs to the LCA5 family.

59894:PHF20
gene id: 59894:PHF20
uniprot id: A0A803V3I3
uniprot id: A0A803VE72
names: Subcellular Location Annotation
messages: Nucleus

59894:IRF1
gene id: 59894:IRF1
uniprot id: A0A803V075
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

59894:CSAD
gene id: 59894:CSAD
uniprot id: U3JP28
names: Similarity
messages: Belongs to the group II decarboxylase family.

59894:GDPD4
gene id: 59894:GDPD4
uniprot id: U3JYR2
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

59894:TTC39A
gene id: 59894:TTC39A
uniprot id: A0A803V8U2
names: Similarity
messages: Belongs to the TTC39 family.

59894:GOLGA5
gene id: 59894:GOLGA5
uniprot id: A0A803VTZ1
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

59894:OGG1
gene id: 59894:OGG1
uniprot id: A0A803W6W3
names: Similarity
messages: Belongs to the type-1 OGG1 family.

59894:RBBP7
gene id: 59894:RBBP7
uniprot id: U3JP07
names: Subcellular Location Annotation
messages: Nucleus

59894:FABP3
gene id: 59894:FABP3
uniprot id: A0A803VAR7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:SRPX
gene id: 59894:SRPX
uniprot id: A0A803VHJ1
uniprot id: U3JFU9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ZNF622
gene id: 59894:ZNF622
uniprot id: U3JYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

59894:FZD6
gene id: 59894:FZD6
uniprot id: U3JTU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:ZC3H12B
gene id: 59894:ZC3H12B
uniprot id: A0A803VGB8
names: Similarity
messages: Belongs to the ZC3H12 family.

59894:B4GALT6
gene id: 59894:B4GALT6
uniprot id: U3JTU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

59894:LYVE1
gene id: 59894:LYVE1
uniprot id: U3JE45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ORM2
gene id: 59894:ORM2
uniprot id: U3JEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

59894:TIE1
gene id: 59894:TIE1
uniprot id: U3JSW5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:TRAPPC11
gene id: 59894:TRAPPC11
uniprot id: U3KB09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

59894:PACS2
gene id: 59894:PACS2
uniprot id: U3JLU6
names: Similarity
messages: Belongs to the PACS family.

59894:SERINC1
gene id: 59894:SERINC1
uniprot id: U3K9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

59894:MSL3
gene id: 59894:MSL3
uniprot id: U3JPG6
names: Subcellular Location Annotation
messages: Nucleus

59894:TK1
gene id: 59894:TK1
uniprot id: U3KCF4
names: Similarity
messages: Belongs to the thymidine kinase family.

59894:GLP2R
gene id: 59894:GLP2R
uniprot id: U3JD61
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101808861
gene id: 59894:LOC101808861
uniprot id: U3KEV7
names: Similarity
messages: Belongs to the AccD/PCCB family.

59894:RHCE
gene id: 59894:RHCE
uniprot id: U3JCG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

59894:LOC101815654
gene id: 59894:LOC101815654
uniprot id: A0A803V0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

59894:LOC101815223
gene id: 59894:LOC101815223
uniprot id: U3KIX0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:FGFBP2
gene id: 59894:FGFBP2
uniprot id: U3KJU7
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

59894:RNASET2
gene id: 59894:RNASET2
uniprot id: A0A803VPZ4
uniprot id: U3KCU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

59894:FAM161B
gene id: 59894:FAM161B
uniprot id: U3JUP9
names: Similarity
messages: Belongs to the FAM161 family.

59894:NEK7
gene id: 59894:NEK7
uniprot id: U3JJB6
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:GCLM
gene id: 59894:GCLM
uniprot id: U3JHY2
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

59894:MRPS33
gene id: 59894:MRPS33
uniprot id: A0A803WFY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

59894:MFN2
gene id: 59894:MFN2
uniprot id: U3K5Y1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

59894:TLN1
gene id: 59894:TLN1
uniprot id: A0A803VLU8
uniprot id: U3JHP7
names: Subcellular Location Annotation
messages: cytoskeleton

59894:HGD
gene id: 59894:HGD
uniprot id: U3JRW5
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

59894:CENPV
gene id: 59894:CENPV
uniprot id: U3JU62
names: Similarity
messages: Belongs to the Gfa family.

59894:C6
gene id: 59894:C6
uniprot id: U3JH04
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:F13A1
gene id: 59894:F13A1
uniprot id: A0A803WDU8
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

59894:FAM160A1
gene id: 59894:FAM160A1
uniprot id: U3JWD0
names: Similarity
messages: Belongs to the FHIP family.

59894:POMT1
gene id: 59894:POMT1
uniprot id: U3JFG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

59894:GREM1
gene id: 59894:GREM1
uniprot id: A0A803VYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

59894:SYCP2
gene id: 59894:SYCP2
uniprot id: U3K7X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYCP2 family.
messages: Nucleus

59894:MTFR1
gene id: 59894:MTFR1
uniprot id: A0A803VER5
uniprot id: U3JSF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

59894:PRKACB
gene id: 59894:PRKACB
uniprot id: A0A803VEG6
uniprot id: A0A803VXW9
uniprot id: A0A803WEF3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

59894:CEP295
gene id: 59894:CEP295
uniprot id: U3JBZ5
names: Subcellular Location Annotation
messages: centrosome

59894:CD81
gene id: 59894:CD81
uniprot id: A0A803VNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:GPR68
gene id: 59894:GPR68
uniprot id: U3KJ90
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:GJB3
gene id: 59894:GJB3
uniprot id: A0A803VDH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:POLRMT
gene id: 59894:POLRMT
uniprot id: A0A803VZM2
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

59894:PIK3CA
gene id: 59894:PIK3CA
uniprot id: U3K146
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

59894:DHX30
gene id: 59894:DHX30
uniprot id: A0A803VUH3
uniprot id: U3JH43
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

59894:LITAF
gene id: 59894:LITAF
uniprot id: A0A803VPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

59894:POLR2C
gene id: 59894:POLR2C
uniprot id: A0A803V4P0
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

59894:PRR5L
gene id: 59894:PRR5L
uniprot id: U3KD80
names: Similarity
messages: Belongs to the PROTOR family.

59894:HOXD4
gene id: 59894:HOXD4
uniprot id: A0A803VK65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

59894:HS3ST1
gene id: 59894:HS3ST1
uniprot id: U3KJY7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:PRMT3
gene id: 59894:PRMT3
uniprot id: A0A803VA65
uniprot id: U3JG40
names: Subcellular Location Annotation
messages: Cytoplasm

59894:LOC101820358
gene id: 59894:LOC101820358
uniprot id: U3K2Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

59894:PSMF1
gene id: 59894:PSMF1
uniprot id: U3JTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

59894:LOC101806175
gene id: 59894:LOC101806175
uniprot id: U3JM47
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:FAM193A
gene id: 59894:FAM193A
uniprot id: U3K5F3
names: Similarity
messages: Belongs to the FAM193 family.

59894:CRTAC1
gene id: 59894:CRTAC1
uniprot id: U3K102
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:GALNT10
gene id: 59894:GALNT10
uniprot id: A0A803V2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

59894:HS6ST1
gene id: 59894:HS6ST1
uniprot id: U3JLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

59894:EPYC
gene id: 59894:EPYC
uniprot id: U3K7V2
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

59894:TCP1
gene id: 59894:TCP1
uniprot id: U3KC76
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

59894:CDH11
gene id: 59894:CDH11
uniprot id: U3JYU1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:RAB33B
gene id: 59894:RAB33B
uniprot id: A0A803WA27
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

59894:LOC101820502
gene id: 59894:LOC101820502
uniprot id: U3JTY3
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101814081
gene id: 59894:LOC101814081
uniprot id: A0A803VXB4
names: Similarity
messages: Belongs to the TMEM14 family.

59894:RPL13
gene id: 59894:RPL13
uniprot id: U3JKK9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

59894:ANXA6
gene id: 59894:ANXA6
uniprot id: U3K0D5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

59894:PHACTR3
gene id: 59894:PHACTR3
uniprot id: U3K7Y7
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

59894:OGFR
gene id: 59894:OGFR
uniprot id: A0A803VH38
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

59894:BTF3L4
gene id: 59894:BTF3L4
uniprot id: A0A803V3J7
names: Similarity
messages: Belongs to the NAC-beta family.

59894:CRYBB1
gene id: 59894:CRYBB1
uniprot id: U3K1A4
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

59894:ZNF706
gene id: 59894:ZNF706
uniprot id: A0A803VSX5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:MMP24
gene id: 59894:MMP24
uniprot id: A0A803WH20
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

59894:SPCS1
gene id: 59894:SPCS1
uniprot id: U3K2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:LZIC
gene id: 59894:LZIC
uniprot id: A0A803VWG3
names: Similarity
messages: Belongs to the CTNNBIP1 family.

59894:ADRM1
gene id: 59894:ADRM1
uniprot id: U3K7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

59894:HEATR5B
gene id: 59894:HEATR5B
uniprot id: U3KBI2
names: Similarity
messages: Belongs to the HEATR5 family.

59894:LOC101810290
gene id: 59894:LOC101810290
uniprot id: U3KE68
names: Similarity
messages: Belongs to the CRISP family.

59894:LOC101817308
gene id: 59894:LOC101817308
uniprot id: U3K5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

59894:FAM168B
gene id: 59894:FAM168B
uniprot id: U3JLR4
names: Similarity
messages: Belongs to the FAM168 family.

59894:SBNO1
gene id: 59894:SBNO1
uniprot id: U3K3R4
names: Similarity
messages: Belongs to the SBNO family.

59894:MFSD11
gene id: 59894:MFSD11
uniprot id: U3JDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

59894:PAX3
gene id: 59894:PAX3
uniprot id: U3JW66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

59894:HS6ST2
gene id: 59894:HS6ST2
uniprot id: U3JGK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

59894:TMCO3
gene id: 59894:TMCO3
uniprot id: U3JKZ7
names: Subcellular Location Annotation
messages: Membrane

59894:WDFY2
gene id: 59894:WDFY2
uniprot id: A0A803VC80
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

59894:EIF2S2
gene id: 59894:EIF2S2
uniprot id: A0A803V495
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

59894:CCT3
gene id: 59894:CCT3
uniprot id: U3JIQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

59894:STMN1
gene id: 59894:STMN1
uniprot id: U3JCC4
names: Similarity
messages: Belongs to the stathmin family.

59894:CZH9orf3
gene id: 59894:CZH9orf3
uniprot id: U3JLK7
names: Similarity
messages: Belongs to the peptidase M1 family.

59894:YTHDF2
gene id: 59894:YTHDF2
uniprot id: U3JF82
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

59894:AQP11
gene id: 59894:AQP11
uniprot id: U3JYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

59894:MMACHC
gene id: 59894:MMACHC
uniprot id: A0A803VCZ7
names: Similarity
messages: Belongs to the MMACHC family.

59894:LOC101818147
gene id: 59894:LOC101818147
uniprot id: A0A803VW13
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:LOC101815193
gene id: 59894:LOC101815193
uniprot id: U3JTA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

59894:YWHAH
gene id: 59894:YWHAH
uniprot id: U3JY62
names: Similarity
messages: Belongs to the 14-3-3 family.

59894:ND3
gene id: 59894:ND3
uniprot id: S0ASL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

59894:SDF4
gene id: 59894:SDF4
uniprot id: A0A803V188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

59894:CPEB4
gene id: 59894:CPEB4
uniprot id: A0A803V8D8
names: Similarity
messages: Belongs to the RRM CPEB family.

59894:ETV4
gene id: 59894:ETV4
uniprot id: A0A803W9B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:BMPR1A
gene id: 59894:BMPR1A
uniprot id: U3JW25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

59894:FIGF
gene id: 59894:FIGF
uniprot id: U3JP78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

59894:P4HB
gene id: 59894:P4HB
uniprot id: U3KBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

59894:SBDS
gene id: 59894:SBDS
uniprot id: A0A803W360
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

59894:HBP1
gene id: 59894:HBP1
uniprot id: U3K6P2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

59894:ATG4C
gene id: 59894:ATG4C
uniprot id: U3KDH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

59894:FAM83H
gene id: 59894:FAM83H
uniprot id: A0A803W3N4
names: Similarity
messages: Belongs to the FAM83 family.

59894:PLA2G4F
gene id: 59894:PLA2G4F
uniprot id: U3JTL6
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

59894:USP49
gene id: 59894:USP49
uniprot id: U3JJW3
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:MCOLN2
gene id: 59894:MCOLN2
uniprot id: A0A803WE49
uniprot id: U3JUJ2
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

59894:UHRF2
gene id: 59894:UHRF2
uniprot id: U3K7R8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

59894:TFRC
gene id: 59894:TFRC
uniprot id: U3JYE7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

59894:NUP107
gene id: 59894:NUP107
uniprot id: U3K6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

59894:LARS2
gene id: 59894:LARS2
uniprot id: U3JIX2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

59894:UBE2R2
gene id: 59894:UBE2R2
uniprot id: A0A803VZ21
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

59894:SF3B1
gene id: 59894:SF3B1
uniprot id: U3JNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

59894:ANKRD34C
gene id: 59894:ANKRD34C
uniprot id: U3K8Y6
names: Similarity
messages: Belongs to the ANKRD34 family.

59894:BCAR1
gene id: 59894:BCAR1
uniprot id: U3JYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

59894:PER2
gene id: 59894:PER2
uniprot id: U3JN88
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:WISP2
gene id: 59894:WISP2
uniprot id: A0A803WDW5
names: Similarity
messages: Belongs to the CCN family.

59894:POLL
gene id: 59894:POLL
uniprot id: U3K1T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

59894:DLC1
gene id: 59894:DLC1
uniprot id: U3JM73
names: Subcellular Location Annotation
messages: Cytoplasm

59894:AGL
gene id: 59894:AGL
uniprot id: A0A803VW93
uniprot id: U3JI98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

59894:EXOC2
gene id: 59894:EXOC2
uniprot id: A0A803W719
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

59894:WNT10A
gene id: 59894:WNT10A
uniprot id: U3JNI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:PDCL
gene id: 59894:PDCL
uniprot id: U3JH34
names: Similarity
messages: Belongs to the phosducin family.

59894:KATNAL2
gene id: 59894:KATNAL2
uniprot id: U3K2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

59894:LOC101815382
gene id: 59894:LOC101815382
uniprot id: U3JPA0
names: Subcellular Location Annotation
messages: Cytoplasm

59894:ETFA
gene id: 59894:ETFA
uniprot id: A0A803VML8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

59894:LOC101817018
gene id: 59894:LOC101817018
uniprot id: U3KIF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

59894:AARS
gene id: 59894:AARS
uniprot id: U3JXK4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

59894:SLC5A1
gene id: 59894:SLC5A1
uniprot id: U3JY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

59894:SLC35A1
gene id: 59894:SLC35A1
uniprot id: A0A803W4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

59894:HMGB2
gene id: 59894:HMGB2
uniprot id: U3KAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

59894:SLC7A1
gene id: 59894:SLC7A1
uniprot id: A0A803V067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

59894:NSMCE1
gene id: 59894:NSMCE1
uniprot id: U3KI27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

59894:MAFF
gene id: 59894:MAFF
uniprot id: U3KDQ9
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

59894:PIK3CG
gene id: 59894:PIK3CG
uniprot id: U3K6Q5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

59894:LOC101820513
gene id: 59894:LOC101820513
uniprot id: A0A803VCA6
uniprot id: U3K090
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

59894:FAM135A
gene id: 59894:FAM135A
uniprot id: A0A803V3V4
uniprot id: A0A803W3I0
names: Similarity
messages: Belongs to the FAM135 family.

59894:LOC101807340
gene id: 59894:LOC101807340
uniprot id: A0A803V5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

59894:HMGCS1
gene id: 59894:HMGCS1
uniprot id: A0A803WCL3
uniprot id: U3K9C6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

59894:UBE2C
gene id: 59894:UBE2C
uniprot id: A0A803V7M3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

59894:C28H19orf25
gene id: 59894:C28H19orf25
uniprot id: U3KHX9
names: Similarity
messages: Belongs to the UPF0449 family.

59894:LOC101807290
gene id: 59894:LOC101807290
uniprot id: A0A803V759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:THRAP3
gene id: 59894:THRAP3
uniprot id: A0A803WFT7
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

59894:MID1IP1
gene id: 59894:MID1IP1
uniprot id: U3KJE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

59894:RAB14
gene id: 59894:RAB14
uniprot id: A0A803VJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

59894:BRAF
gene id: 59894:BRAF
uniprot id: U3JMB6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

59894:LOC101820640
gene id: 59894:LOC101820640
uniprot id: U3JJ51
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

59894:FAM126A
gene id: 59894:FAM126A
uniprot id: A0A803V4B5
uniprot id: A0A803VH93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

59894:LOC101816047
gene id: 59894:LOC101816047
uniprot id: U3K6Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

59894:VWA2
gene id: 59894:VWA2
uniprot id: U3JHS1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101807222
gene id: 59894:LOC101807222
uniprot id: A0A803W8L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

59894:CEP170
gene id: 59894:CEP170
uniprot id: A0A803V5P8
uniprot id: A0A803VVF1
uniprot id: A0A803W3L0
names: Similarity
messages: Belongs to the CEP170 family.

59894:ONECUT1
gene id: 59894:ONECUT1
uniprot id: U3KBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

59894:PPP2R3C
gene id: 59894:PPP2R3C
uniprot id: U3JU09
names: Subcellular Location Annotation
messages: Nucleus

59894:LHFP
gene id: 59894:LHFP
uniprot id: A0A803V1N6
uniprot id: A0A803V1Y4
names: Subcellular Location Annotation
messages: Membrane

59894:FYN
gene id: 59894:FYN
uniprot id: A0A803W6D8
uniprot id: A0A803WAX9
uniprot id: U3K8R9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:PRICKLE2
gene id: 59894:PRICKLE2
uniprot id: U3KFN9
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

59894:FRK
gene id: 59894:FRK
uniprot id: U3K8V7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:ATP8A2
gene id: 59894:ATP8A2
uniprot id: U3K1Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

59894:AP1G1
gene id: 59894:AP1G1
uniprot id: A0A803V0M9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

59894:SCUBE3
gene id: 59894:SCUBE3
uniprot id: A0A803V5Z8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:ARMC8
gene id: 59894:ARMC8
uniprot id: A0A803VDA8
uniprot id: U3KG93
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:HAAO
gene id: 59894:HAAO
uniprot id: U3KDT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

59894:SUV39H2
gene id: 59894:SUV39H2
uniprot id: U3JGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

59894:UBE3A
gene id: 59894:UBE3A
uniprot id: A0A803VS17
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

59894:CLNS1A
gene id: 59894:CLNS1A
uniprot id: A0A803VPV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

59894:VOPP1
gene id: 59894:VOPP1
uniprot id: A0A803V5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

59894:ATP11B
gene id: 59894:ATP11B
uniprot id: A0A803WDK0
uniprot id: U3K0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

59894:LOC101813797
gene id: 59894:LOC101813797
uniprot id: U3KA49
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:SV2C
gene id: 59894:SV2C
uniprot id: U3K616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

59894:LOC101821578
gene id: 59894:LOC101821578
uniprot id: U3K6R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:OPRK1
gene id: 59894:OPRK1
uniprot id: U3K6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
messages: Interacts with NHERF1. Interacts with GABARAPL1.
messages: Membrane

59894:TNFRSF25
gene id: 59894:TNFRSF25
uniprot id: A0A803W014
uniprot id: U3K5B9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:KAT7
gene id: 59894:KAT7
uniprot id: A0A803V6P7
uniprot id: U3JRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

59894:COPS4
gene id: 59894:COPS4
uniprot id: U3JSV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

59894:FAM26D
gene id: 59894:FAM26D
uniprot id: U3K8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

59894:ATRNL1
gene id: 59894:ATRNL1
uniprot id: A0A803VAB6
uniprot id: U3JHR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:COMTD1
gene id: 59894:COMTD1
uniprot id: U3JWU1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

59894:PACSIN1
gene id: 59894:PACSIN1
uniprot id: U3JMC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

59894:GOSR2
gene id: 59894:GOSR2
uniprot id: U3JYT1
names: Subcellular Location Annotation
messages: Membrane

59894:METAP1
gene id: 59894:METAP1
uniprot id: A0A803W0N2
uniprot id: U3JUM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

59894:OTUD7A
gene id: 59894:OTUD7A
uniprot id: U3KDI3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:PPIL3
gene id: 59894:PPIL3
uniprot id: A0A803V7A1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

59894:LOC101814279
gene id: 59894:LOC101814279
uniprot id: A0A803W7R1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:TBC1D31
gene id: 59894:TBC1D31
uniprot id: U3JIE1
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

59894:LDB3
gene id: 59894:LDB3
uniprot id: A0A803UZY0
uniprot id: A0A803V3A3
uniprot id: A0A803VHJ2
uniprot id: A0A803VMC7
names: Subcellular Location Annotation
messages: Z line

59894:SIAH3
gene id: 59894:SIAH3
uniprot id: U3K0I2
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

59894:UHRF1
gene id: 59894:UHRF1
uniprot id: U3JEN0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

59894:GPR65
gene id: 59894:GPR65
uniprot id: U3KJB9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:ST3GAL1
gene id: 59894:ST3GAL1
uniprot id: A0A803VL42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:RNF13
gene id: 59894:RNF13
uniprot id: A0A803VC81
names: Subcellular Location Annotation
messages: Membrane

59894:LGMN
gene id: 59894:LGMN
uniprot id: A0A803VVZ0
names: Similarity
messages: Belongs to the peptidase C13 family.

59894:GJD2
gene id: 59894:GJD2
uniprot id: A0A803WES4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:MRPS7
gene id: 59894:MRPS7
uniprot id: U3JEK3
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

59894:PLCB2
gene id: 59894:PLCB2
uniprot id: U3JED2
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

59894:LBH
gene id: 59894:LBH
uniprot id: A0A803VH06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

59894:ALG14
gene id: 59894:ALG14
uniprot id: U3JI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

59894:LOC101819115
gene id: 59894:LOC101819115
uniprot id: U3JBA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Monomer.
messages: Secreted

59894:SLC20A2
gene id: 59894:SLC20A2
uniprot id: A0A803VH75
uniprot id: U3JVH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

59894:PDHA1
gene id: 59894:PDHA1
uniprot id: U3JNT7
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

59894:FLCN
gene id: 59894:FLCN
uniprot id: U3KH81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

59894:CDH5
gene id: 59894:CDH5
uniprot id: U3JYU9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:EFL1
gene id: 59894:EFL1
uniprot id: U3K978
names: Subcellular Location Annotation
messages: Nucleus

59894:MYT1
gene id: 59894:MYT1
uniprot id: U3K6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

59894:SPON2
gene id: 59894:SPON2
uniprot id: U3K637
names: Subcellular Location Annotation
messages: extracellular matrix

59894:NR1H3
gene id: 59894:NR1H3
uniprot id: U3JUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

59894:BIRC7
gene id: 59894:BIRC7
uniprot id: U3K7A6
names: Similarity
messages: Belongs to the IAP family.

59894:LOC101815656
gene id: 59894:LOC101815656
uniprot id: U3KAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LIPI
gene id: 59894:LIPI
uniprot id: U3KCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

59894:ZC2HC1C
gene id: 59894:ZC2HC1C
uniprot id: A0A803WBN5
uniprot id: U3JV16
names: Similarity
messages: Belongs to the ZC2HC1 family.

59894:NR1H4
gene id: 59894:NR1H4
uniprot id: U3K961
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

59894:LOC101813211
gene id: 59894:LOC101813211
uniprot id: U3KA04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

59894:LOC101818597
gene id: 59894:LOC101818597
uniprot id: U3KKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:OTX2
gene id: 59894:OTX2
uniprot id: U3JM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

59894:LOC101819072
gene id: 59894:LOC101819072
uniprot id: U3KKQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:CACYBP
gene id: 59894:CACYBP
uniprot id: A0A803W0L0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

59894:S100B
gene id: 59894:S100B
uniprot id: A0A803V4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

59894:TOR4A
gene id: 59894:TOR4A
uniprot id: U3KIE0
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

59894:RGMA
gene id: 59894:RGMA
uniprot id: U3K707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

59894:RAMP3
gene id: 59894:RAMP3
uniprot id: U3KFJ4
names: Similarity
messages: Belongs to the RAMP family.

59894:NAAA
gene id: 59894:NAAA
uniprot id: U3K172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid ceramidase family.
messages: Lysosome

59894:NKAIN1
gene id: 59894:NKAIN1
uniprot id: U3JEN6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:SLC45A1
gene id: 59894:SLC45A1
uniprot id: A0A803V1Y5
uniprot id: U3K5N3
names: Subcellular Location Annotation
messages: Membrane

59894:SEC22C
gene id: 59894:SEC22C
uniprot id: U3JE30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

59894:UBE2K
gene id: 59894:UBE2K
uniprot id: A0A803WAR4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

59894:LMBR1
gene id: 59894:LMBR1
uniprot id: U3JWP7
names: Similarity
messages: Belongs to the LIMR family.

59894:HAO1
gene id: 59894:HAO1
uniprot id: U3K8Q1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

59894:CMC2
gene id: 59894:CMC2
uniprot id: A0A803VTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

59894:SLC25A38
gene id: 59894:SLC25A38
uniprot id: A0A803VCX3
uniprot id: U3KD19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

59894:UTS2B
gene id: 59894:UTS2B
uniprot id: U3JXY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

59894:MGMT
gene id: 59894:MGMT
uniprot id: U3JEQ5
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

59894:PSMB1
gene id: 59894:PSMB1
uniprot id: U3JKQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

59894:ACBD5
gene id: 59894:ACBD5
uniprot id: U3JXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

59894:GRM3
gene id: 59894:GRM3
uniprot id: U3JGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

59894:TMEM33
gene id: 59894:TMEM33
uniprot id: A0A803VC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

59894:CDC20
gene id: 59894:CDC20
uniprot id: U3JST6
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

59894:ATP8B2
gene id: 59894:ATP8B2
uniprot id: U3JEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

59894:NR5A2
gene id: 59894:NR5A2
uniprot id: A0A803WA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

59894:NMB
gene id: 59894:NMB
uniprot id: U3K5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

59894:TNFRSF1A
gene id: 59894:TNFRSF1A
uniprot id: U3JRP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101822000
gene id: 59894:LOC101822000
uniprot id: U3JPH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

59894:RAP2B
gene id: 59894:RAP2B
uniprot id: U3KJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

59894:CENPJ
gene id: 59894:CENPJ
uniprot id: U3K288
names: Similarity
messages: Belongs to the TCP10 family.

59894:SLC7A11
gene id: 59894:SLC7A11
uniprot id: U3JQL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

59894:SLC4A11
gene id: 59894:SLC4A11
uniprot id: A0A803VEU8
uniprot id: A0A803VEY0
uniprot id: A0A803WF64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

59894:NDUFB1
gene id: 59894:NDUFB1
uniprot id: U3JI93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

59894:MRPS30
gene id: 59894:MRPS30
uniprot id: U3K9K2
names: Subcellular Location Annotation
messages: Mitochondrion

59894:MAPK8IP3
gene id: 59894:MAPK8IP3
uniprot id: A0A803VRH5
names: Similarity
messages: Belongs to the JIP scaffold family.

59894:CFAP206
gene id: 59894:CFAP206
uniprot id: U3JJT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme

59894:BCO1
gene id: 59894:BCO1
uniprot id: U3JWF5
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

59894:HTR1F
gene id: 59894:HTR1F
uniprot id: U3KJS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

59894:CHMP1A
gene id: 59894:CHMP1A
uniprot id: U3JKF3
names: Similarity
messages: Belongs to the SNF7 family.

59894:ACSF2
gene id: 59894:ACSF2
uniprot id: U3JEY2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

59894:MANBA
gene id: 59894:MANBA
uniprot id: U3K0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

59894:ESR2
gene id: 59894:ESR2
uniprot id: U3JKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

59894:VCAN
gene id: 59894:VCAN
uniprot id: U3KEK5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

59894:TPST1
gene id: 59894:TPST1
uniprot id: A0A803VK31
uniprot id: U3JW51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

59894:ITGA4
gene id: 59894:ITGA4
uniprot id: U3JLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

59894:UBAP2L
gene id: 59894:UBAP2L
uniprot id: A0A803W7Q7
uniprot id: A0A803WGF2
uniprot id: U3JEM6
names: Subcellular Location Annotation
messages: Cytoplasm

59894:SNU13
gene id: 59894:SNU13
uniprot id: A0A803VAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

59894:ARHGDIA
gene id: 59894:ARHGDIA
uniprot id: A0A803V688
names: Similarity
messages: Belongs to the Rho GDI family.

59894:LOC101817647
gene id: 59894:LOC101817647
uniprot id: A0A803VG75
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

59894:CAPRIN1
gene id: 59894:CAPRIN1
uniprot id: A0A803VDD0
uniprot id: A0A803VII7
uniprot id: A0A803WBX2
names: Similarity
messages: Belongs to the caprin family.

59894:UGGT2
gene id: 59894:UGGT2
uniprot id: U3JPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

59894:SSTR3
gene id: 59894:SSTR3
uniprot id: U3KLD3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:RIDA
gene id: 59894:RIDA
uniprot id: U3JT39
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

59894:FAM102A
gene id: 59894:FAM102A
uniprot id: U3JEZ9
names: Similarity
messages: Belongs to the EEIG family.

59894:COPB1
gene id: 59894:COPB1
uniprot id: U3JDR1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

59894:SCAMP4
gene id: 59894:SCAMP4
uniprot id: A0A803V4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

59894:HSPA13
gene id: 59894:HSPA13
uniprot id: A0A803VK83
names: Similarity
messages: Belongs to the heat shock protein 70 family.

59894:TOP3A
gene id: 59894:TOP3A
uniprot id: U3KH13
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

59894:DDX47
gene id: 59894:DDX47
uniprot id: U3KA38
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

59894:GDAP2
gene id: 59894:GDAP2
uniprot id: U3JRA0
names: Similarity
messages: Belongs to the GDAP2 family.

59894:PLOD2
gene id: 59894:PLOD2
uniprot id: A0A803V590
uniprot id: U3JX88
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

59894:DUSP10
gene id: 59894:DUSP10
uniprot id: U3KC19
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

59894:MAK16
gene id: 59894:MAK16
uniprot id: U3JWG5
names: Similarity
messages: Belongs to the MAK16 family.

59894:SERPINB5
gene id: 59894:SERPINB5
uniprot id: U3KEX6
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

59894:CDK7
gene id: 59894:CDK7
uniprot id: U3K5J1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

59894:TIMM23
gene id: 59894:TIMM23
uniprot id: U3JW84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

59894:SURF4
gene id: 59894:SURF4
uniprot id: A0A803VY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:SH3GL2
gene id: 59894:SH3GL2
uniprot id: U3JK71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

59894:FGGY
gene id: 59894:FGGY
uniprot id: U3KD05
names: Similarity
messages: Belongs to the FGGY kinase family.

59894:JMJD1C
gene id: 59894:JMJD1C
uniprot id: U3KFP2
names: Subcellular Location Annotation
messages: Nucleus

59894:DCSTAMP
gene id: 59894:DCSTAMP
uniprot id: A0A803VCR3
names: Subcellular Location Annotation
messages: Membrane

59894:EMC3
gene id: 59894:EMC3
uniprot id: U3K263
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

59894:CZH5orf28
gene id: 59894:CZH5orf28
uniprot id: A0A803V209
names: Subcellular Location Annotation
messages: Membrane

59894:KPNA2
gene id: 59894:KPNA2
uniprot id: U3JI37
names: Similarity
messages: Belongs to the importin alpha family.

59894:LOC101809625
gene id: 59894:LOC101809625
uniprot id: A0A803VSS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

59894:REV1
gene id: 59894:REV1
uniprot id: U3JMS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

59894:LOC101808699
gene id: 59894:LOC101808699
uniprot id: A0A803WA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:IL1RL1
gene id: 59894:IL1RL1
uniprot id: U3JM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: axon
messages: dendrite

59894:TMOD1
gene id: 59894:TMOD1
uniprot id: A0A803VD13
uniprot id: U3JEM3
names: Subcellular Location Annotation
messages: cytoskeleton

59894:RHBDD1
gene id: 59894:RHBDD1
uniprot id: U3JWJ7
names: Subcellular Location Annotation
messages: Membrane

59894:MCM6
gene id: 59894:MCM6
uniprot id: U3KH43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

59894:LOC101806737
gene id: 59894:LOC101806737
uniprot id: A0A803V0I8
names: Similarity
messages: Belongs to the cytochrome b5 family.

59894:LOC101810807
gene id: 59894:LOC101810807
uniprot id: U3JWV1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

59894:PPARA
gene id: 59894:PPARA
uniprot id: U3JJL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

59894:PTPRM
gene id: 59894:PTPRM
uniprot id: U3JV32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

59894:DNAJB14
gene id: 59894:DNAJB14
uniprot id: A0A803VE50
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:FAM188B
gene id: 59894:FAM188B
uniprot id: U3JDI1
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

59894:CD40
gene id: 59894:CD40
uniprot id: U3JQG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ORC5
gene id: 59894:ORC5
uniprot id: U3K6Y8
names: Subcellular Location Annotation
messages: Nucleus

59894:PTP4A1
gene id: 59894:PTP4A1
uniprot id: U3JG42
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

59894:LOC101806043
gene id: 59894:LOC101806043
uniprot id: U3KBN2
names: Similarity
messages: Belongs to the cyclin family.

59894:EMX2
gene id: 59894:EMX2
uniprot id: A0A803VIJ3
names: Subcellular Location Annotation
messages: Nucleus

59894:GAD1
gene id: 59894:GAD1
uniprot id: U3JGZ0
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

59894:IREB2
gene id: 59894:IREB2
uniprot id: U3K7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

59894:LOC101817954
gene id: 59894:LOC101817954
uniprot id: A0A803VLE0
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:ZFYVE9
gene id: 59894:ZFYVE9
uniprot id: U3JSP6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

59894:C1H2orf40
gene id: 59894:C1H2orf40
uniprot id: U3JLV2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

59894:BLCAP
gene id: 59894:BLCAP
uniprot id: U3KLP8
names: Similarity
messages: Belongs to the BLCAP family.

59894:GRIA1
gene id: 59894:GRIA1
uniprot id: A0A803W9W6
uniprot id: U3K0R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

59894:SLC26A7
gene id: 59894:SLC26A7
uniprot id: U3JRY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

59894:KRT222
gene id: 59894:KRT222
uniprot id: U3JC62
names: Similarity
messages: Belongs to the intermediate filament family.

59894:REEP3
gene id: 59894:REEP3
uniprot id: U3KFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

59894:TRAPPC2
gene id: 59894:TRAPPC2
uniprot id: U3JPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

59894:LOC101820149
gene id: 59894:LOC101820149
uniprot id: U3JSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space
messages: Required for assembly of mitochondrial respiratory chain complexes.

59894:CPSF4
gene id: 59894:CPSF4
uniprot id: A0A803V2Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

59894:TIMP3
gene id: 59894:TIMP3
uniprot id: A0A803W427
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

59894:SLC7A2
gene id: 59894:SLC7A2
uniprot id: A0A803W985
uniprot id: U3K9Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

59894:HDAC2
gene id: 59894:HDAC2
uniprot id: U3K8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

59894:STAT1
gene id: 59894:STAT1
uniprot id: U3JP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

59894:ALG12
gene id: 59894:ALG12
uniprot id: U3K4T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:ACAN
gene id: 59894:ACAN
uniprot id: U3K7A3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

59894:STT3B
gene id: 59894:STT3B
uniprot id: A0A803W1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

59894:RAN
gene id: 59894:RAN
uniprot id: A0A803W5F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

59894:RBBP8
gene id: 59894:RBBP8
uniprot id: U3JUG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

59894:LOC101819037
gene id: 59894:LOC101819037
uniprot id: A0A803W4T2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:C4H4orf48
gene id: 59894:C4H4orf48
uniprot id: U3K5L1
names: Subcellular Location Annotation
messages: Secreted

59894:ARID1B
gene id: 59894:ARID1B
uniprot id: U3KDG9
names: Subcellular Location Annotation
messages: Nucleus

59894:RIC8A
gene id: 59894:RIC8A
uniprot id: U3KA99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

59894:MAPK6
gene id: 59894:MAPK6
uniprot id: U3KBI0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

59894:TSPAN12
gene id: 59894:TSPAN12
uniprot id: U3K5X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

59894:LOC101811636
gene id: 59894:LOC101811636
uniprot id: U3JTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

59894:LOC101813749
gene id: 59894:LOC101813749
uniprot id: U3KF16
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

59894:GAS8
gene id: 59894:GAS8
uniprot id: U3JK25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

59894:FAM3B
gene id: 59894:FAM3B
uniprot id: U3JHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

59894:SLC8A1
gene id: 59894:SLC8A1
uniprot id: U3JI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

59894:NEURL2
gene id: 59894:NEURL2
uniprot id: U3JPR4
names: Subcellular Location Annotation
messages: Cytoplasm

59894:LOC101816078
gene id: 59894:LOC101816078
uniprot id: U3K011
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

59894:SNAP23
gene id: 59894:SNAP23
uniprot id: U3JSX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

59894:BCOR
gene id: 59894:BCOR
uniprot id: A0A803VFA1
uniprot id: U3JFR0
names: Similarity
messages: Belongs to the BCOR family.

59894:BTBD10
gene id: 59894:BTBD10
uniprot id: A0A803WE69
uniprot id: U3K7W1
names: Subcellular Location Annotation
messages: Cytoplasm

59894:LOC101809951
gene id: 59894:LOC101809951
uniprot id: A0A803WEA5
names: Similarity
messages: Belongs to the glucagon family.

59894:RWDD3
gene id: 59894:RWDD3
uniprot id: A0A803VNH8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:LOC101819789
gene id: 59894:LOC101819789
uniprot id: U3KCW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: gem
messages: neuron projection

59894:RAB9B
gene id: 59894:RAB9B
uniprot id: U3KL64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

59894:SEMA3D
gene id: 59894:SEMA3D
uniprot id: U3K7V5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ITIH5
gene id: 59894:ITIH5
uniprot id: U3JGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

59894:CSGALNACT2
gene id: 59894:CSGALNACT2
uniprot id: U3JWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

59894:BORCS7
gene id: 59894:BORCS7
uniprot id: A0A803VGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Lysosome membrane
messages: Membrane

59894:NFYA
gene id: 59894:NFYA
uniprot id: A0A803W6A7
uniprot id: U3JJW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

59894:KCNS2
gene id: 59894:KCNS2
uniprot id: U3KKJ2
names: Subcellular Location Annotation
messages: Membrane

59894:RBP7
gene id: 59894:RBP7
uniprot id: U3JXQ7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:ZNRF3
gene id: 59894:ZNRF3
uniprot id: U3K0U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

59894:MTM1
gene id: 59894:MTM1
uniprot id: A0A803V162
uniprot id: U3KCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

59894:KIF2A
gene id: 59894:KIF2A
uniprot id: U3K953
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:S100Z
gene id: 59894:S100Z
uniprot id: A0A803VFY7
names: Similarity
messages: Belongs to the S-100 family.

59894:PRKD3
gene id: 59894:PRKD3
uniprot id: U3KB53
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

59894:PLCB4
gene id: 59894:PLCB4
uniprot id: A0A803W169
uniprot id: U3K9D5
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

59894:DLGAP5
gene id: 59894:DLGAP5
uniprot id: A0A803V1Q5
names: Similarity
messages: Belongs to the SAPAP family.

59894:SGO1
gene id: 59894:SGO1
uniprot id: U3K3K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

59894:YIPF5
gene id: 59894:YIPF5
uniprot id: U3K2U2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:SKIL
gene id: 59894:SKIL
uniprot id: U3K1R1
names: Similarity
messages: Belongs to the SKI family.

59894:ELOVL5
gene id: 59894:ELOVL5
uniprot id: A0A803VPD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

59894:LOC101809038
gene id: 59894:LOC101809038
uniprot id: U3KKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:DDX4
gene id: 59894:DDX4
uniprot id: A0A803V8I5
names: Similarity
messages: Belongs to the DEAD box helicase family.

59894:RAD21L1
gene id: 59894:RAD21L1
uniprot id: U3JTA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

59894:SLC35E4
gene id: 59894:SLC35E4
uniprot id: A0A803VMM9
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101815312
gene id: 59894:LOC101815312
uniprot id: U3JZN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

59894:LOC101821869
gene id: 59894:LOC101821869
uniprot id: U3JWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

59894:DHRS7
gene id: 59894:DHRS7
uniprot id: U3JLE6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:GADL1
gene id: 59894:GADL1
uniprot id: U3K3E9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

59894:FAM102B
gene id: 59894:FAM102B
uniprot id: U3JJ21
names: Similarity
messages: Belongs to the EEIG family.

59894:AGXT2
gene id: 59894:AGXT2
uniprot id: U3JHD1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

59894:PLCD1
gene id: 59894:PLCD1
uniprot id: A0A803WDQ9
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

59894:PLEKHA8
gene id: 59894:PLEKHA8
uniprot id: U3K3V6
names: Subcellular Location Annotation
messages: trans-Golgi network membrane

59894:LOC101816392
gene id: 59894:LOC101816392
uniprot id: A0A803WGA2
uniprot id: U3JJN6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

59894:SLBP
gene id: 59894:SLBP
uniprot id: U3K5Y6
names: Similarity
messages: Belongs to the SLBP family.

59894:NFX1
gene id: 59894:NFX1
uniprot id: U3KFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

59894:BVES
gene id: 59894:BVES
uniprot id: U3KAQ3
names: Similarity
messages: Belongs to the popeye family.

59894:KPNA7
gene id: 59894:KPNA7
uniprot id: U3KHB8
names: Similarity
messages: Belongs to the importin alpha family.

59894:AMOT
gene id: 59894:AMOT
uniprot id: U3K8Y7
names: Similarity
messages: Belongs to the angiomotin family.

59894:WNT7B
gene id: 59894:WNT7B
uniprot id: A0A803VW64
uniprot id: U3JJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:GPN2
gene id: 59894:GPN2
uniprot id: U3JC23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

59894:TRMT11
gene id: 59894:TRMT11
uniprot id: A0A803W725
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

59894:NUDT21
gene id: 59894:NUDT21
uniprot id: U3JYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

59894:IL1R1
gene id: 59894:IL1R1
uniprot id: U3JM67
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

59894:NDUFB3
gene id: 59894:NDUFB3
uniprot id: U3JNF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

59894:STON2
gene id: 59894:STON2
uniprot id: U3KDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: synaptosome

59894:MST1
gene id: 59894:MST1
uniprot id: U3K2Y8
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:KCNA1
gene id: 59894:KCNA1
uniprot id: U3KKD6
names: Subcellular Location Annotation
messages: Membrane

59894:PLP1
gene id: 59894:PLP1
uniprot id: A0A803W052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

59894:CCDC94
gene id: 59894:CCDC94
uniprot id: U3JEA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

59894:PIGG
gene id: 59894:PIGG
uniprot id: A0A803VXT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:DENND6A
gene id: 59894:DENND6A
uniprot id: U3K125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

59894:ANKS1A
gene id: 59894:ANKS1A
uniprot id: U3JM60
names: Subcellular Location Annotation
messages: Cytoplasm

59894:LOC101821454
gene id: 59894:LOC101821454
uniprot id: A0A803VEB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101820328
gene id: 59894:LOC101820328
uniprot id: A0A803V056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:MTMR7
gene id: 59894:MTMR7
uniprot id: A0A803WFD2
uniprot id: U3K9Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

59894:ALX1
gene id: 59894:ALX1
uniprot id: U3K7J7
names: Subcellular Location Annotation
messages: Nucleus

59894:VPS37B
gene id: 59894:VPS37B
uniprot id: A0A803VS10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

59894:EHF
gene id: 59894:EHF
uniprot id: A0A803WGI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:SNX14
gene id: 59894:SNX14
uniprot id: A0A803VYU5
uniprot id: U3JJQ8
names: Similarity
messages: Belongs to the sorting nexin family.

59894:IK
gene id: 59894:IK
uniprot id: U3K4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

59894:TRIM32
gene id: 59894:TRIM32
uniprot id: U3KJC2
names: Similarity
messages: Belongs to the TRIM/RBCC family.

59894:DARS2
gene id: 59894:DARS2
uniprot id: U3JZX3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

59894:LIPC
gene id: 59894:LIPC
uniprot id: U3KCN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:MAST2
gene id: 59894:MAST2
uniprot id: A0A803W2J5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

59894:LOC101811424
gene id: 59894:LOC101811424
uniprot id: U3KJC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

59894:UBLCP1
gene id: 59894:UBLCP1
uniprot id: U3K1G6
names: Subcellular Location Annotation
messages: Nucleus

59894:VPS36
gene id: 59894:VPS36
uniprot id: U3K1M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

59894:LOC101808643
gene id: 59894:LOC101808643
uniprot id: A0A803WBF3
names: Similarity
messages: Belongs to the copine family.

59894:SUPT6H
gene id: 59894:SUPT6H
uniprot id: U3JV64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

59894:ASF1A
gene id: 59894:ASF1A
uniprot id: U3K9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

59894:PIK3CB
gene id: 59894:PIK3CB
uniprot id: U3JN97
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

59894:INSIG2
gene id: 59894:INSIG2
uniprot id: U3KGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

59894:LOC101810933
gene id: 59894:LOC101810933
uniprot id: U3JFV9
names: Subcellular Location Annotation
messages: Membrane

59894:CDKN3
gene id: 59894:CDKN3
uniprot id: U3JMH5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

59894:WLS
gene id: 59894:WLS
uniprot id: U3KES4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

59894:TACR3
gene id: 59894:TACR3
uniprot id: U3K0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:TMEM63C
gene id: 59894:TMEM63C
uniprot id: U3KE70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

59894:PPEF1
gene id: 59894:PPEF1
uniprot id: U3JNX7
names: Similarity
messages: Belongs to the PPP phosphatase family.

59894:SUSD5
gene id: 59894:SUSD5
uniprot id: U3JRF4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:KCNJ8
gene id: 59894:KCNJ8
uniprot id: A0A803VQ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

59894:SAP130
gene id: 59894:SAP130
uniprot id: A0A803VW51
uniprot id: U3JLN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

59894:RAMP2
gene id: 59894:RAMP2
uniprot id: U3JD90
names: Similarity
messages: Belongs to the RAMP family.

59894:RRN3
gene id: 59894:RRN3
uniprot id: U3JMM1
names: Similarity
messages: Belongs to the RRN3 family.

59894:LOC101817312
gene id: 59894:LOC101817312
uniprot id: U3KKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:SSTR2
gene id: 59894:SSTR2
uniprot id: U3KKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

59894:SEC24C
gene id: 59894:SEC24C
uniprot id: A0A803WFX8
uniprot id: U3JX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

59894:STK38L
gene id: 59894:STK38L
uniprot id: U3JMU5
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:TBL1XR1
gene id: 59894:TBL1XR1
uniprot id: U3K169
names: Similarity
messages: Belongs to the WD repeat EBI family.

59894:RXFP1
gene id: 59894:RXFP1
uniprot id: U3JK81
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:CTSZ
gene id: 59894:CTSZ
uniprot id: A0A803VT50
names: Similarity
messages: Belongs to the peptidase C1 family.

59894:KIAA0196
gene id: 59894:KIAA0196
uniprot id: U3JIN6
names: Similarity
messages: Belongs to the strumpellin family.

59894:SLU7
gene id: 59894:SLU7
uniprot id: U3KGA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

59894:LOC101812558
gene id: 59894:LOC101812558
uniprot id: U3KLQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

59894:SH3GL1
gene id: 59894:SH3GL1
uniprot id: A0A803V9V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

59894:LOC101818267
gene id: 59894:LOC101818267
uniprot id: A0A803VII2
uniprot id: U3JLW2
names: Similarity
messages: Belongs to the DDI1 family.

59894:TSEN2
gene id: 59894:TSEN2
uniprot id: U3JB59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

59894:PDE7B
gene id: 59894:PDE7B
uniprot id: A0A803VL79
uniprot id: A0A803VU93
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:FGD3
gene id: 59894:FGD3
uniprot id: A0A803V3B1
names: Subcellular Location Annotation
messages: cytoskeleton

59894:WASF3
gene id: 59894:WASF3
uniprot id: A0A803W718
uniprot id: U3K1X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

59894:RFX3
gene id: 59894:RFX3
uniprot id: A0A803WAH2
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101813582
gene id: 59894:LOC101813582
uniprot id: A0A803WGS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:EPN2
gene id: 59894:EPN2
uniprot id: A0A803V4L4
uniprot id: A0A803VRW7
names: Similarity
messages: Belongs to the epsin family.

59894:LOC101813169
gene id: 59894:LOC101813169
uniprot id: A0A803VK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

59894:EPHA6
gene id: 59894:EPHA6
uniprot id: U3JG07
names: Subcellular Location Annotation
messages: Membrane

59894:EYA1
gene id: 59894:EYA1
uniprot id: A0A803VGU5
uniprot id: A0A803VNE3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

59894:CLDN34
gene id: 59894:CLDN34
uniprot id: U3KLB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

59894:C1H11orf73
gene id: 59894:C1H11orf73
uniprot id: A0A803W075
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

59894:EXOSC9
gene id: 59894:EXOSC9
uniprot id: U3K0W5
names: Subcellular Location Annotation
messages: Cytoplasm

59894:LOC101819449
gene id: 59894:LOC101819449
uniprot id: U3KB99
names: Subcellular Location Annotation
messages: Membrane

59894:CELF5
gene id: 59894:CELF5
uniprot id: U3KHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

59894:DMAP1
gene id: 59894:DMAP1
uniprot id: U3JRU6
names: Subcellular Location Annotation
messages: Nucleus

59894:ACAD9
gene id: 59894:ACAD9
uniprot id: U3JB78
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

59894:YY1
gene id: 59894:YY1
uniprot id: U3JJ42
names: Similarity
messages: Belongs to the YY transcription factor family.

59894:ARTN
gene id: 59894:ARTN
uniprot id: U3JS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

59894:NUDT1
gene id: 59894:NUDT1
uniprot id: U3KHL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

59894:PLN
gene id: 59894:PLN
uniprot id: U3KLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

59894:PAQR8
gene id: 59894:PAQR8
uniprot id: U3KKB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

59894:RTCA
gene id: 59894:RTCA
uniprot id: U3JID7
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

59894:CYTB
gene id: 59894:CYTB
uniprot id: Q7HN24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

59894:LOC101807457
gene id: 59894:LOC101807457
uniprot id: U3K2C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

59894:SLC25A44
gene id: 59894:SLC25A44
uniprot id: U3JIS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:GSDMA
gene id: 59894:GSDMA
uniprot id: U3JCH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

59894:NCOA7
gene id: 59894:NCOA7
uniprot id: A0A803VHK5
uniprot id: U3KAB5
names: Similarity
messages: Belongs to the OXR1 family.

59894:LOC101807147
gene id: 59894:LOC101807147
uniprot id: U3JTF9
names: Similarity
messages: Belongs to the CEMIP family.

59894:ZDHHC8
gene id: 59894:ZDHHC8
uniprot id: A0A803VVT5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:SGMS1
gene id: 59894:SGMS1
uniprot id: A0A803W881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

59894:PTEN
gene id: 59894:PTEN
uniprot id: A0A803VMH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

59894:TAF2
gene id: 59894:TAF2
uniprot id: A0A803V9B4
uniprot id: U3JI55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

59894:LOC101815602
gene id: 59894:LOC101815602
uniprot id: U3JNE7
names: Similarity
messages: Belongs to the peptidase C14A family.

59894:MKNK1
gene id: 59894:MKNK1
uniprot id: U3K423
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:PROM1
gene id: 59894:PROM1
uniprot id: A0A803VYJ2
uniprot id: U3K3R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

59894:PSMD5
gene id: 59894:PSMD5
uniprot id: U3JGG4
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

59894:PODXL2
gene id: 59894:PODXL2
uniprot id: U3JZJ5
names: Subcellular Location Annotation
messages: Membrane

59894:SMAD1
gene id: 59894:SMAD1
uniprot id: U3JSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

59894:LRRC8B
gene id: 59894:LRRC8B
uniprot id: U3JG25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

59894:POFUT1
gene id: 59894:POFUT1
uniprot id: U3JSB3
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

59894:NMBR
gene id: 59894:NMBR
uniprot id: U3KE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:CDKN1A
gene id: 59894:CDKN1A
uniprot id: A0A803VE43
names: Similarity
messages: Belongs to the CDI family.

59894:MTHFD1
gene id: 59894:MTHFD1
uniprot id: U3JKR6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

59894:LOC101811630
gene id: 59894:LOC101811630
uniprot id: U3KKZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:HACL1
gene id: 59894:HACL1
uniprot id: U3K3S4
names: Similarity
messages: Belongs to the TPP enzyme family.

59894:CPO
gene id: 59894:CPO
uniprot id: U3JN00
names: Similarity
messages: Belongs to the peptidase M14 family.

59894:SLC1A3
gene id: 59894:SLC1A3
uniprot id: U3JH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

59894:DMD
gene id: 59894:DMD
uniprot id: A0A803V1B5
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

59894:LOC101813011
gene id: 59894:LOC101813011
uniprot id: U3KKS0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:GPD2
gene id: 59894:GPD2
uniprot id: U3JK58
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

59894:COQ6
gene id: 59894:COQ6
uniprot id: U3JUR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

59894:SMAD2
gene id: 59894:SMAD2
uniprot id: A0A803VG84
uniprot id: U3K2R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

59894:ZPBP2
gene id: 59894:ZPBP2
uniprot id: U3JCJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted
messages: acrosome

59894:COG4
gene id: 59894:COG4
uniprot id: U3JY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

59894:DCBLD1
gene id: 59894:DCBLD1
uniprot id: U3K989
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:TCFL5
gene id: 59894:TCFL5
uniprot id: A0A803VTP1
names: Subcellular Location Annotation
messages: Nucleus

59894:UTP6
gene id: 59894:UTP6
uniprot id: U3JHX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP6 family.
messages: nucleolus

59894:NPTX2
gene id: 59894:NPTX2
uniprot id: U3KHS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101812762
gene id: 59894:LOC101812762
uniprot id: U3KGW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:FAM149B1
gene id: 59894:FAM149B1
uniprot id: A0A803W091
uniprot id: U3KED3
names: Similarity
messages: Belongs to the FAM149 family.

59894:CRHR1
gene id: 59894:CRHR1
uniprot id: U3K060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

59894:IDE
gene id: 59894:IDE
uniprot id: U3JZT6
names: Similarity
messages: Belongs to the peptidase M16 family.

59894:DRD4
gene id: 59894:DRD4
uniprot id: U3K8S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:ATG2B
gene id: 59894:ATG2B
uniprot id: U3JIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

59894:SUFU
gene id: 59894:SUFU
uniprot id: U3K235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

59894:TM9SF3
gene id: 59894:TM9SF3
uniprot id: U3JXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

59894:HOOK1
gene id: 59894:HOOK1
uniprot id: A0A803W6D2
uniprot id: U3KD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

59894:PIWIL1
gene id: 59894:PIWIL1
uniprot id: U3K4E1
names: Similarity
messages: Belongs to the argonaute family.

59894:CCND1
gene id: 59894:CCND1
uniprot id: U3JFA0
names: Similarity
messages: Belongs to the cyclin family.

59894:LOC101813268
gene id: 59894:LOC101813268
uniprot id: U3JFV7
names: Subcellular Location Annotation
messages: Membrane

59894:BEGAIN
gene id: 59894:BEGAIN
uniprot id: U3JJ65
names: Subcellular Location Annotation
messages: Membrane

59894:DHRS7B
gene id: 59894:DHRS7B
uniprot id: A0A803VEW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:VTI1A
gene id: 59894:VTI1A
uniprot id: A0A803VI63
uniprot id: A0A803WCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

59894:ATXN1
gene id: 59894:ATXN1
uniprot id: U3KG31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

59894:HDAC1
gene id: 59894:HDAC1
uniprot id: U3JD04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

59894:PTER
gene id: 59894:PTER
uniprot id: A0A803VP81
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:PIAS4
gene id: 59894:PIAS4
uniprot id: U3JDP5
names: Similarity
messages: Belongs to the PIAS family.

59894:LOC101812471
gene id: 59894:LOC101812471
uniprot id: U3JH66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

59894:CDH8
gene id: 59894:CDH8
uniprot id: U3JC08
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:LOC101811103
gene id: 59894:LOC101811103
uniprot id: U3KG79
names: Similarity
messages: Belongs to the globin family.

59894:ATL2
gene id: 59894:ATL2
uniprot id: U3JI43
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

59894:OSBPL5
gene id: 59894:OSBPL5
uniprot id: A0A803W7S0
names: Similarity
messages: Belongs to the OSBP family.

59894:PREPL
gene id: 59894:PREPL
uniprot id: U3KEW7
names: Similarity
messages: Belongs to the peptidase S9A family.

59894:GATA3
gene id: 59894:GATA3
uniprot id: U3JGN9
names: Subcellular Location Annotation
messages: Nucleus

59894:PRPF38A
gene id: 59894:PRPF38A
uniprot id: U3JST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

59894:TIPARP
gene id: 59894:TIPARP
uniprot id: U3JQC1
names: Similarity
messages: Belongs to the ARTD/PARP family.

59894:PGD
gene id: 59894:PGD
uniprot id: U3JXN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

59894:RSL24D1
gene id: 59894:RSL24D1
uniprot id: U3KBX8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

59894:ELF2
gene id: 59894:ELF2
uniprot id: U3JQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:SEMA5B
gene id: 59894:SEMA5B
uniprot id: A0A803VQH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:DDIAS
gene id: 59894:DDIAS
uniprot id: A0A803W4V7
names: Similarity
messages: Belongs to the replication factor A protein 1 family.

59894:IFRD1
gene id: 59894:IFRD1
uniprot id: U3K4E4
names: Similarity
messages: Belongs to the IFRD family.

59894:CLDN11
gene id: 59894:CLDN11
uniprot id: A0A803VBS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:DENR
gene id: 59894:DENR
uniprot id: A0A803VX47
names: Similarity
messages: Belongs to the DENR family.

59894:PHTF1
gene id: 59894:PHTF1
uniprot id: U3JLK3
names: Subcellular Location Annotation
messages: Membrane

59894:FBXO25
gene id: 59894:FBXO25
uniprot id: U3JH09
names: Subcellular Location Annotation
messages: Nucleus

59894:TJP3
gene id: 59894:TJP3
uniprot id: U3KAU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

59894:STX18
gene id: 59894:STX18
uniprot id: A0A803V8X6
uniprot id: A0A803V9K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

59894:TMEM47
gene id: 59894:TMEM47
uniprot id: A0A803W7P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

59894:RASGRP1
gene id: 59894:RASGRP1
uniprot id: U3JSX8
names: Similarity
messages: Belongs to the RASGRP family.

59894:ALDH1A1
gene id: 59894:ALDH1A1
uniprot id: U3KED1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

59894:LOC101818018
gene id: 59894:LOC101818018
uniprot id: U3KLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:PDCD5
gene id: 59894:PDCD5
uniprot id: U3JBV4
names: Similarity
messages: Belongs to the PDCD5 family.

59894:SMAD3
gene id: 59894:SMAD3
uniprot id: A0A803V7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

59894:FAM3D
gene id: 59894:FAM3D
uniprot id: A0A803WGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

59894:KCNJ4
gene id: 59894:KCNJ4
uniprot id: A0A803VZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

59894:NTNG1
gene id: 59894:NTNG1
uniprot id: A0A803VC76
uniprot id: A0A803VM89
uniprot id: A0A803VVA2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:SUSD6
gene id: 59894:SUSD6
uniprot id: U3JQX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CACNA2D1
gene id: 59894:CACNA2D1
uniprot id: A0A803W702
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

59894:ISCU
gene id: 59894:ISCU
uniprot id: A0A803VM54
names: Similarity
messages: Belongs to the NifU family.

59894:EIF4E2
gene id: 59894:EIF4E2
uniprot id: U3JZ76
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

59894:KCNK10
gene id: 59894:KCNK10
uniprot id: A0A803VWH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

59894:LOC101817598
gene id: 59894:LOC101817598
uniprot id: U3JRU4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

59894:TM4SF4
gene id: 59894:TM4SF4
uniprot id: U3JRX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

59894:CEBPG
gene id: 59894:CEBPG
uniprot id: U3KIW3
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

59894:FAM13C
gene id: 59894:FAM13C
uniprot id: A0A803VRS6
names: Similarity
messages: Belongs to the FAM13 family.

59894:SLF2
gene id: 59894:SLF2
uniprot id: U3K203
names: Similarity
messages: Belongs to the FAM178 family.

59894:PSD2
gene id: 59894:PSD2
uniprot id: U3K4A0
names: Subcellular Location Annotation
messages: ruffle membrane

59894:TMEM182
gene id: 59894:TMEM182
uniprot id: U3JM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

59894:ACER3
gene id: 59894:ACER3
uniprot id: U3JYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

59894:CSNK1D
gene id: 59894:CSNK1D
uniprot id: A0A803VR45
uniprot id: A0A803VUM9
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:CSK
gene id: 59894:CSK
uniprot id: U3K8U1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:C1GALT1
gene id: 59894:C1GALT1
uniprot id: A0A803VL27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
messages: Membrane

59894:FLT1
gene id: 59894:FLT1
uniprot id: U3K1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

59894:RPS7
gene id: 59894:RPS7
uniprot id: A0A803W540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

59894:FAM198B
gene id: 59894:FAM198B
uniprot id: A0A803VHW4
names: Similarity
messages: Belongs to the GASK family.

59894:CPNE3
gene id: 59894:CPNE3
uniprot id: U3JR63
names: Similarity
messages: Belongs to the copine family.

59894:ARF3
gene id: 59894:ARF3
uniprot id: A0A803W6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

59894:HMOX2
gene id: 59894:HMOX2
uniprot id: U3JNT3
names: Similarity
messages: Belongs to the heme oxygenase family.

59894:HPGD
gene id: 59894:HPGD
uniprot id: A0A803VGL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:CPQ
gene id: 59894:CPQ
uniprot id: A0A803VGU2
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

59894:TMOD3
gene id: 59894:TMOD3
uniprot id: A0A803W3Y5
names: Subcellular Location Annotation
messages: cytoskeleton

59894:EXOC3L1
gene id: 59894:EXOC3L1
uniprot id: U3JX77
names: Similarity
messages: Belongs to the SEC6 family.

59894:SLA
gene id: 59894:SLA
uniprot id: A0A803VEZ4
names: Subcellular Location Annotation
messages: Cytoplasm

59894:TTC26
gene id: 59894:TTC26
uniprot id: U3KAP2
names: Similarity
messages: Belongs to the IFT56 family.

59894:MANBAL
gene id: 59894:MANBAL
uniprot id: U3JSM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

59894:DGCR14
gene id: 59894:DGCR14
uniprot id: A0A803V228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

59894:UBIAD1
gene id: 59894:UBIAD1
uniprot id: A0A803WA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

59894:ABHD3
gene id: 59894:ABHD3
uniprot id: U3JUH7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

59894:CDH10
gene id: 59894:CDH10
uniprot id: U3JYV7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:FGF1
gene id: 59894:FGF1
uniprot id: A0A803W399
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

59894:CHRNB3
gene id: 59894:CHRNB3
uniprot id: U3JRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:BCL2A1
gene id: 59894:BCL2A1
uniprot id: A0A803V184
names: Similarity
messages: Belongs to the Bcl-2 family.

59894:SPTBN1
gene id: 59894:SPTBN1
uniprot id: A0A803WC77
uniprot id: U3K9Y0
names: Similarity
messages: Belongs to the spectrin family.

59894:DHODH
gene id: 59894:DHODH
uniprot id: U3JJ10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

59894:IDS
gene id: 59894:IDS
uniprot id: U3KC79
names: Similarity
messages: Belongs to the sulfatase family.

59894:MELK
gene id: 59894:MELK
uniprot id: A0A803V465
uniprot id: U3KEV6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

59894:KCNK5
gene id: 59894:KCNK5
uniprot id: A0A803V502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

59894:RPS6KB2
gene id: 59894:RPS6KB2
uniprot id: U3KCI2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

59894:DTYMK
gene id: 59894:DTYMK
uniprot id: A0A803VUG2
names: Similarity
messages: Belongs to the thymidylate kinase family.

59894:ARL6IP4
gene id: 59894:ARL6IP4
uniprot id: U3K3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

59894:SLC25A15
gene id: 59894:SLC25A15
uniprot id: U3K1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:LOC101812386
gene id: 59894:LOC101812386
uniprot id: A0A803VKG9
names: Similarity
messages: Belongs to the gonadal family.

59894:NUDT3
gene id: 59894:NUDT3
uniprot id: U3JME6
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

59894:DAPK3
gene id: 59894:DAPK3
uniprot id: U3JDM8
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:ND1
gene id: 59894:ND1
uniprot id: S0AU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

59894:CCDC85C
gene id: 59894:CCDC85C
uniprot id: A0A803V4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

59894:LOC101808938
gene id: 59894:LOC101808938
uniprot id: U3JSR7
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

59894:N6AMT1
gene id: 59894:N6AMT1
uniprot id: A0A803VLL9
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

59894:HAO2
gene id: 59894:HAO2
uniprot id: U3JR20
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

59894:SMAD5
gene id: 59894:SMAD5
uniprot id: U3K056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

59894:CROT
gene id: 59894:CROT
uniprot id: U3JYZ4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

59894:GABPA
gene id: 59894:GABPA
uniprot id: U3KBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:ST6GAL2
gene id: 59894:ST6GAL2
uniprot id: A0A803V3N8
uniprot id: A0A803VF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:LOC101807214
gene id: 59894:LOC101807214
uniprot id: U3KDS6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:SIRT5
gene id: 59894:SIRT5
uniprot id: U3KGB5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-102 and Arg-105) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

59894:STAG1
gene id: 59894:STAG1
uniprot id: U3KGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

59894:TPM4
gene id: 59894:TPM4
uniprot id: A0A803VRS4
uniprot id: A0A803W2U2
uniprot id: U3KGA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

59894:LIAS
gene id: 59894:LIAS
uniprot id: A0A803WDT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

59894:GNB5
gene id: 59894:GNB5
uniprot id: U3KBJ0
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

59894:RPS6KA6
gene id: 59894:RPS6KA6
uniprot id: U3JN67
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

59894:KCNJ13
gene id: 59894:KCNJ13
uniprot id: A0A803VQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

59894:ADCY1
gene id: 59894:ADCY1
uniprot id: U3KFJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

59894:PEX5L
gene id: 59894:PEX5L
uniprot id: A0A803V614
uniprot id: A0A803VNN3
uniprot id: U3K0Z2
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

59894:GALNT11
gene id: 59894:GALNT11
uniprot id: U3JWH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

59894:LCOR
gene id: 59894:LCOR
uniprot id: A0A803VCZ1
names: Subcellular Location Annotation
messages: Nucleus

59894:PWP2
gene id: 59894:PWP2
uniprot id: U3KCT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

59894:LOC101808809
gene id: 59894:LOC101808809
uniprot id: U3JXR9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

59894:LOC101816899
gene id: 59894:LOC101816899
uniprot id: U3KL15
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:LOC101806183
gene id: 59894:LOC101806183
uniprot id: A0A803VKW0
names: Similarity
messages: Belongs to the NSG family.

59894:TF
gene id: 59894:TF
uniprot id: U3JK93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

59894:GALE
gene id: 59894:GALE
uniprot id: U3JCM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

59894:ACO1
gene id: 59894:ACO1
uniprot id: U3JEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

59894:HPS5
gene id: 59894:HPS5
uniprot id: U3K9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

59894:TRAF1
gene id: 59894:TRAF1
uniprot id: U3JGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

59894:FAM150B
gene id: 59894:FAM150B
uniprot id: U3JH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

59894:SLC39A9
gene id: 59894:SLC39A9
uniprot id: A0A803VME6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

59894:TOP2A
gene id: 59894:TOP2A
uniprot id: U3JC95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

59894:DDX51
gene id: 59894:DDX51
uniprot id: U3JXN4
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

59894:TWF2
gene id: 59894:TWF2
uniprot id: A0A803W9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

59894:DPYD
gene id: 59894:DPYD
uniprot id: A0A803WCL9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

59894:GABRA5
gene id: 59894:GABRA5
uniprot id: U3JN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:MAN2A2
gene id: 59894:MAN2A2
uniprot id: A0A803V1R2
uniprot id: U3K9F5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

59894:LMX1B
gene id: 59894:LMX1B
uniprot id: U3JHQ4
names: Subcellular Location Annotation
messages: Nucleus

59894:ACTA2
gene id: 59894:ACTA2
uniprot id: U3JYY8
names: Similarity
messages: Belongs to the actin family.

59894:CX3CR1
gene id: 59894:CX3CR1
uniprot id: U3KIU0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:SNCG
gene id: 59894:SNCG
uniprot id: U3JW34
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

59894:CCDC85A
gene id: 59894:CCDC85A
uniprot id: A0A803VPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

59894:LOC101808955
gene id: 59894:LOC101808955
uniprot id: U3JNE2
names: Subcellular Location Annotation
messages: Membrane

59894:SORL1
gene id: 59894:SORL1
uniprot id: U3JTL2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family. SORL1 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Recycling endosome membrane
messages: Secreted
messages: multivesicular body membrane
messages: secretory vesicle membrane
messages: trans-Golgi network membrane

59894:PPARG
gene id: 59894:PPARG
uniprot id: A0A803VB57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

59894:SLC41A1
gene id: 59894:SLC41A1
uniprot id: U3JCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

59894:ABCD2
gene id: 59894:ABCD2
uniprot id: U3K657
names: Subcellular Location Annotation
messages: Membrane

59894:NSUN7
gene id: 59894:NSUN7
uniprot id: U3JJM9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC107604091
gene id: 59894:LOC107604091
uniprot id: U3JR04
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

59894:SAMM50
gene id: 59894:SAMM50
uniprot id: U3JVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

59894:LOC101818225
gene id: 59894:LOC101818225
uniprot id: A0A803WD01
names: Similarity
messages: Belongs to the aldo/keto reductase family.

59894:LPGAT1
gene id: 59894:LPGAT1
uniprot id: U3KDB0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

59894:MED23
gene id: 59894:MED23
uniprot id: A0A803VPZ3
uniprot id: U3KB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 23 family.
messages: Nucleus

59894:CSMD3
gene id: 59894:CSMD3
uniprot id: U3JHY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CHPF2
gene id: 59894:CHPF2
uniprot id: U3KFH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

59894:ADCYAP1
gene id: 59894:ADCYAP1
uniprot id: A0A803WD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

59894:MYLK
gene id: 59894:MYLK
uniprot id: U3KG18
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

59894:SQLE
gene id: 59894:SQLE
uniprot id: U3JIN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

59894:HMGA2
gene id: 59894:HMGA2
uniprot id: U3K5Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

59894:FAM168A
gene id: 59894:FAM168A
uniprot id: A0A803VP75
names: Similarity
messages: Belongs to the FAM168 family.

59894:NME5
gene id: 59894:NME5
uniprot id: U3JYX3
names: Similarity
messages: Belongs to the NDK family.

59894:RPL11
gene id: 59894:RPL11
uniprot id: U3JCM9
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

59894:GALR3
gene id: 59894:GALR3
uniprot id: U3KE94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

59894:CRMP1
gene id: 59894:CRMP1
uniprot id: U3K4P1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

59894:SNAP25
gene id: 59894:SNAP25
uniprot id: U3K932
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

59894:IGBP1
gene id: 59894:IGBP1
uniprot id: U3JNK0
names: Similarity
messages: Belongs to the IGBP1/TAP42 family.

59894:AOX1
gene id: 59894:AOX1
uniprot id: U3JNN8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

59894:SIX4
gene id: 59894:SIX4
uniprot id: A0A803V2H6
names: Subcellular Location Annotation
messages: Nucleus

59894:GPN3
gene id: 59894:GPN3
uniprot id: U3K3M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

59894:PDS5B
gene id: 59894:PDS5B
uniprot id: U3K171
names: Subcellular Location Annotation
messages: Nucleus

59894:INTS7
gene id: 59894:INTS7
uniprot id: U3KD91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

59894:LYAR
gene id: 59894:LYAR
uniprot id: U3K461
names: Subcellular Location Annotation
messages: Cytoplasm

59894:CDCA7L
gene id: 59894:CDCA7L
uniprot id: U3K558
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:ARHGAP26
gene id: 59894:ARHGAP26
uniprot id: U3K2T8
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

59894:POP4
gene id: 59894:POP4
uniprot id: U3JBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

59894:RNF168
gene id: 59894:RNF168
uniprot id: A0A803WD69
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF168 family.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

59894:CALCR
gene id: 59894:CALCR
uniprot id: A0A803VAM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

59894:KCNK9
gene id: 59894:KCNK9
uniprot id: A0A803V4V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

59894:LOC101813391
gene id: 59894:LOC101813391
uniprot id: U3JXQ5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:GABRR3
gene id: 59894:GABRR3
uniprot id: A0A803W4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:LOC101806331
gene id: 59894:LOC101806331
uniprot id: U3JMY8
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

59894:LMNB2
gene id: 59894:LMNB2
uniprot id: U3KBT5
names: Similarity
messages: Belongs to the intermediate filament family.

59894:BTG4
gene id: 59894:BTG4
uniprot id: U3JUD8
names: Similarity
messages: Belongs to the BTG family.

59894:ATP6
gene id: 59894:ATP6
uniprot id: S0AU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

59894:PEX2
gene id: 59894:PEX2
uniprot id: U3KKL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

59894:LOC101813838
gene id: 59894:LOC101813838
uniprot id: U3JZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

59894:FLI1
gene id: 59894:FLI1
uniprot id: A0A803VL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:CIRBP
gene id: 59894:CIRBP
uniprot id: U3KHV9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

59894:TMEM39B
gene id: 59894:TMEM39B
uniprot id: U3JD06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

59894:UGP2
gene id: 59894:UGP2
uniprot id: U3KGN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

59894:LOC101817111
gene id: 59894:LOC101817111
uniprot id: U3K5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

59894:SLC37A4
gene id: 59894:SLC37A4
uniprot id: A0A803VBY6
uniprot id: A0A803VVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

59894:LGI1
gene id: 59894:LGI1
uniprot id: U3JZF5
names: Subcellular Location Annotation
messages: Secreted

59894:RPAP2
gene id: 59894:RPAP2
uniprot id: U3JGB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

59894:CREBL2
gene id: 59894:CREBL2
uniprot id: A0A803VRV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

59894:ARL6
gene id: 59894:ARL6
uniprot id: U3JG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

59894:SESN3
gene id: 59894:SESN3
uniprot id: U3JC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

59894:TGFBR1
gene id: 59894:TGFBR1
uniprot id: A0A803VUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

59894:FRZB
gene id: 59894:FRZB
uniprot id: U3KFC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

59894:LOC101815404
gene id: 59894:LOC101815404
uniprot id: U3JTQ9
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

59894:PHACTR1
gene id: 59894:PHACTR1
uniprot id: A0A803VAW0
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

59894:RAB19
gene id: 59894:RAB19
uniprot id: U3JM63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

59894:ORAI2
gene id: 59894:ORAI2
uniprot id: A0A803WAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

59894:PTH1R
gene id: 59894:PTH1R
uniprot id: U3JRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

59894:CA10
gene id: 59894:CA10
uniprot id: U3JDJ3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

59894:GNB1
gene id: 59894:GNB1
uniprot id: U3K477
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

59894:OGT
gene id: 59894:OGT
uniprot id: U3KB11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

59894:TPH2
gene id: 59894:TPH2
uniprot id: A0A803WAC5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

59894:MYO19
gene id: 59894:MYO19
uniprot id: U3JS10
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

59894:LOC101818061
gene id: 59894:LOC101818061
uniprot id: U3JZB7
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:KATNAL1
gene id: 59894:KATNAL1
uniprot id: U3K1H1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

59894:YTHDC1
gene id: 59894:YTHDC1
uniprot id: A0A803VPP8
uniprot id: U3JVQ8
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

59894:RPL23A
gene id: 59894:RPL23A
uniprot id: U3JV50
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

59894:CHRFAM7A
gene id: 59894:CHRFAM7A
uniprot id: A0A803VYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:GTF2B
gene id: 59894:GTF2B
uniprot id: U3JFZ7
names: Similarity
messages: Belongs to the TFIIB family.

59894:PHYHIPL
gene id: 59894:PHYHIPL
uniprot id: A0A803VDL6
names: Similarity
messages: Belongs to the PHYHIP family.

59894:PGPEP1L
gene id: 59894:PGPEP1L
uniprot id: U3K6Z0
names: Similarity
messages: Belongs to the peptidase C15 family.

59894:CLDN5
gene id: 59894:CLDN5
uniprot id: U3KJB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:CUTC
gene id: 59894:CUTC
uniprot id: A0A803V159
uniprot id: U3K0I0
names: Similarity
messages: Belongs to the CutC family.

59894:NOP58
gene id: 59894:NOP58
uniprot id: U3JN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

59894:ADIPOR2
gene id: 59894:ADIPOR2
uniprot id: A0A803VN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

59894:ERGIC2
gene id: 59894:ERGIC2
uniprot id: U3K684
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

59894:CTBP2
gene id: 59894:CTBP2
uniprot id: U3JQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

59894:SLCO1C1
gene id: 59894:SLCO1C1
uniprot id: U3K0B2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:PRDM5
gene id: 59894:PRDM5
uniprot id: U3K129
names: Subcellular Location Annotation
messages: Nucleus

59894:SRP68
gene id: 59894:SRP68
uniprot id: U3JE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Cytoplasm
messages: nucleolus

59894:RBP5
gene id: 59894:RBP5
uniprot id: U3JPT7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:PRKAR1B
gene id: 59894:PRKAR1B
uniprot id: A0A803VYS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

59894:FAM105A
gene id: 59894:FAM105A
uniprot id: A0A803V8M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

59894:MYO1C
gene id: 59894:MYO1C
uniprot id: A0A803VW52
uniprot id: A0A803W7K4
uniprot id: U3JW13
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

59894:FRRS1
gene id: 59894:FRRS1
uniprot id: U3JI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

59894:LOC101815720
gene id: 59894:LOC101815720
uniprot id: U3JX53
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

59894:MAATS1
gene id: 59894:MAATS1
uniprot id: U3JS41
names: Similarity
messages: Belongs to the CFAP91 family.

59894:BTAF1
gene id: 59894:BTAF1
uniprot id: U3JZU4
names: Subcellular Location Annotation
messages: Nucleus

59894:SHMT1
gene id: 59894:SHMT1
uniprot id: U3KGZ9
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

59894:PPARD
gene id: 59894:PPARD
uniprot id: U3JM40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:VIM
gene id: 59894:VIM
uniprot id: U3JYD1
names: Similarity
messages: Belongs to the intermediate filament family.

59894:TCP11L2
gene id: 59894:TCP11L2
uniprot id: U3KG59
names: Similarity
messages: Belongs to the TCP11 family.

59894:EBF1
gene id: 59894:EBF1
uniprot id: A0A803V2L1
uniprot id: U3K1F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

59894:HOXA6
gene id: 59894:HOXA6
uniprot id: U3K496
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

59894:HSP90AB1
gene id: 59894:HSP90AB1
uniprot id: A0A803W9W0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

59894:IRF6
gene id: 59894:IRF6
uniprot id: U3JCL5
names: Subcellular Location Annotation
messages: Nucleus

59894:BRMS1L
gene id: 59894:BRMS1L
uniprot id: U3JUD9
names: Subcellular Location Annotation
messages: Nucleus

59894:ATP5L
gene id: 59894:ATP5L
uniprot id: A0A803W1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

59894:SLCO2A1
gene id: 59894:SLCO2A1
uniprot id: A0A803VTE6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:DSG4
gene id: 59894:DSG4
uniprot id: U3JTY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: desmosome

59894:LOC101812606
gene id: 59894:LOC101812606
uniprot id: U3JP95
names: Similarity
messages: Belongs to the intermediate filament family.

59894:KCNK2
gene id: 59894:KCNK2
uniprot id: U3KCS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

59894:APOD
gene id: 59894:APOD
uniprot id: U3JXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

59894:CASK
gene id: 59894:CASK
uniprot id: A0A803VA48
uniprot id: A0A803VHI9
uniprot id: U3JFN2
names: Similarity
messages: Belongs to the MAGUK family.

59894:LOC101808823
gene id: 59894:LOC101808823
uniprot id: U3KJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

59894:LOC107603574
gene id: 59894:LOC107603574
uniprot id: U3JBL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

59894:MPV17L
gene id: 59894:MPV17L
uniprot id: A0A803VR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

59894:GGA3
gene id: 59894:GGA3
uniprot id: A0A803VSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

59894:DGKE
gene id: 59894:DGKE
uniprot id: U3JHW3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

59894:TFAP2D
gene id: 59894:TFAP2D
uniprot id: U3KE72
names: Similarity
messages: Belongs to the AP-2 family.

59894:POLR2F
gene id: 59894:POLR2F
uniprot id: U3KE37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

59894:PIK3C2A
gene id: 59894:PIK3C2A
uniprot id: U3JDF0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

59894:LOC101812019
gene id: 59894:LOC101812019
uniprot id: U3KKZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:TAF1
gene id: 59894:TAF1
uniprot id: A0A803VZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

59894:RAB3C
gene id: 59894:RAB3C
uniprot id: U3K8X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

59894:INHBA
gene id: 59894:INHBA
uniprot id: U3JRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

59894:NDUFS7
gene id: 59894:NDUFS7
uniprot id: A0A803VSQ6
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

59894:TFDP1
gene id: 59894:TFDP1
uniprot id: U3JL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

59894:DNASE2B
gene id: 59894:DNASE2B
uniprot id: A0A803VMP2
names: Similarity
messages: Belongs to the DNase II family.

59894:CRKL
gene id: 59894:CRKL
uniprot id: A0A803V182
names: Similarity
messages: Belongs to the CRK family.

59894:DR1
gene id: 59894:DR1
uniprot id: A0A803V4N1
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

59894:LOC101806316
gene id: 59894:LOC101806316
uniprot id: A0A803WAN6
names: Similarity
messages: Belongs to the NDK family.

59894:PITPNM1
gene id: 59894:PITPNM1
uniprot id: U3JF35
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

59894:TACC3
gene id: 59894:TACC3
uniprot id: U3K5V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

59894:RNASEH2B
gene id: 59894:RNASEH2B
uniprot id: A0A803VWS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

59894:CEP19
gene id: 59894:CEP19
uniprot id: A0A803VNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

59894:CPN1
gene id: 59894:CPN1
uniprot id: U3K037
names: Similarity
messages: Belongs to the peptidase M14 family.

59894:UBAC2
gene id: 59894:UBAC2
uniprot id: A0A803VA41
names: Subcellular Location Annotation
messages: Membrane

59894:LHFPL2
gene id: 59894:LHFPL2
uniprot id: A0A803VDF7
names: Subcellular Location Annotation
messages: Membrane

59894:SFXN2
gene id: 59894:SFXN2
uniprot id: U3K247
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

59894:STXBP3
gene id: 59894:STXBP3
uniprot id: A0A803V376
uniprot id: U3JJ38
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

59894:MYOD1
gene id: 59894:MYOD1
uniprot id: U3JDC7
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

59894:CAB39L
gene id: 59894:CAB39L
uniprot id: U3K122
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

59894:TNS3
gene id: 59894:TNS3
uniprot id: A0A803V8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

59894:ARMC1
gene id: 59894:ARMC1
uniprot id: A0A803WFV9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

59894:CHUK
gene id: 59894:CHUK
uniprot id: A0A803VGK2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:AZIN2
gene id: 59894:AZIN2
uniprot id: U3JCU8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

59894:TMEM106B
gene id: 59894:TMEM106B
uniprot id: A0A803V357
names: Similarity
messages: Belongs to the TMEM106 family.

59894:LOC101812865
gene id: 59894:LOC101812865
uniprot id: A0A803VEH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

59894:EPB42
gene id: 59894:EPB42
uniprot id: U3JQT6
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

59894:APOPT1
gene id: 59894:APOPT1
uniprot id: U3JJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

59894:SEC24A
gene id: 59894:SEC24A
uniprot id: U3JZS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

59894:EEF1A2
gene id: 59894:EEF1A2
uniprot id: U3K725
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

59894:TSSC1
gene id: 59894:TSSC1
uniprot id: U3JH87
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

59894:LOC101808949
gene id: 59894:LOC101808949
uniprot id: U3JC60
names: Similarity
messages: Belongs to the intermediate filament family.

59894:E2F8
gene id: 59894:E2F8
uniprot id: U3JFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

59894:MDH1B
gene id: 59894:MDH1B
uniprot id: U3JMW8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

59894:EIF3L
gene id: 59894:EIF3L
uniprot id: U3KE84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

59894:BRE
gene id: 59894:BRE
uniprot id: A0A803VK29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

59894:ITK
gene id: 59894:ITK
uniprot id: U3K153
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:B3GNT5
gene id: 59894:B3GNT5
uniprot id: U3KLK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:LOC101807254
gene id: 59894:LOC101807254
uniprot id: U3JXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

59894:EXOC5
gene id: 59894:EXOC5
uniprot id: U3JM48
names: Similarity
messages: Belongs to the SEC10 family.

59894:PICK1
gene id: 59894:PICK1
uniprot id: U3KDZ4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

59894:ARSI
gene id: 59894:ARSI
uniprot id: U3JZX8
names: Similarity
messages: Belongs to the sulfatase family.

59894:LOC101817760
gene id: 59894:LOC101817760
uniprot id: A0A803W4X1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:CACNG1
gene id: 59894:CACNG1
uniprot id: U3JIA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

59894:PROZ
gene id: 59894:PROZ
uniprot id: A0A803W3B6
uniprot id: U3JKN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:POMGNT1
gene id: 59894:POMGNT1
uniprot id: U3K4F9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

59894:SMARCA2
gene id: 59894:SMARCA2
uniprot id: U3K786
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

59894:LOC101817417
gene id: 59894:LOC101817417
uniprot id: A0A803V757
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:LOC101820325
gene id: 59894:LOC101820325
uniprot id: U3KKZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:UNC45B
gene id: 59894:UNC45B
uniprot id: U3K534
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

59894:EOGT
gene id: 59894:EOGT
uniprot id: A0A803VCD2
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

59894:DPY19L3
gene id: 59894:DPY19L3
uniprot id: A0A803WED5
uniprot id: U3JBU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

59894:YES1
gene id: 59894:YES1
uniprot id: A0A803VWC2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:PTS
gene id: 59894:PTS
uniprot id: U3JUN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

59894:EML4
gene id: 59894:EML4
uniprot id: U3KDR8
names: Similarity
messages: Belongs to the WD repeat EMAP family.

59894:PRDX1
gene id: 59894:PRDX1
uniprot id: U3K4T5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

59894:LOC101817171
gene id: 59894:LOC101817171
uniprot id: A0A803VIJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LOC101811233
gene id: 59894:LOC101811233
uniprot id: U3JU83
names: Similarity
messages: Belongs to the amidase family.

59894:PSMB7
gene id: 59894:PSMB7
uniprot id: U3JHF2
names: Subcellular Location Annotation
messages: Nucleus

59894:PTPN14
gene id: 59894:PTPN14
uniprot id: U3KCV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

59894:LOC101817076
gene id: 59894:LOC101817076
uniprot id: U3JUB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

59894:CDK3
gene id: 59894:CDK3
uniprot id: U3JE29
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:ENTPD1
gene id: 59894:ENTPD1
uniprot id: U3K018
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

59894:PDGFRA
gene id: 59894:PDGFRA
uniprot id: U3JLD9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

59894:CRHR2
gene id: 59894:CRHR2
uniprot id: U3JVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

59894:EME1
gene id: 59894:EME1
uniprot id: U3JF12
names: Similarity
messages: Belongs to the EME1/MMS4 family.

59894:KLHL3
gene id: 59894:KLHL3
uniprot id: A0A803W9E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

59894:GUCY2F
gene id: 59894:GUCY2F
uniprot id: U3JYN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

59894:WEE1
gene id: 59894:WEE1
uniprot id: U3JE23
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

59894:MTMR3
gene id: 59894:MTMR3
uniprot id: A0A803V1C8
uniprot id: A0A803V2K6
uniprot id: A0A803VBD3
uniprot id: U3JWZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

59894:HEXB
gene id: 59894:HEXB
uniprot id: U3K6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

59894:CEP63
gene id: 59894:CEP63
uniprot id: U3KG37
names: Similarity
messages: Belongs to the CEP63 family.

59894:FSCN1
gene id: 59894:FSCN1
uniprot id: U3KHC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

59894:CLPTM1L
gene id: 59894:CLPTM1L
uniprot id: U3JHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

59894:LOC101808519
gene id: 59894:LOC101808519
uniprot id: U3KD29
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:CHST10
gene id: 59894:CHST10
uniprot id: U3JMM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:ST6GALNAC4
gene id: 59894:ST6GALNAC4
uniprot id: U3JF14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:LOC101812092
gene id: 59894:LOC101812092
uniprot id: A0A803W1T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

59894:VPS11
gene id: 59894:VPS11
uniprot id: A0A803V4L8
uniprot id: U3K5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

59894:MEIS1
gene id: 59894:MEIS1
uniprot id: U3KGS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

59894:TET1
gene id: 59894:TET1
uniprot id: U3KEX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

59894:PDGFD
gene id: 59894:PDGFD
uniprot id: A0A803V5H5
uniprot id: U3JCC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:MURC
gene id: 59894:MURC
uniprot id: A0A803V013
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

59894:LGI2
gene id: 59894:LGI2
uniprot id: A0A803VW82
names: Subcellular Location Annotation
messages: Secreted

59894:LOC101821194
gene id: 59894:LOC101821194
uniprot id: U3K252
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:GOT2
gene id: 59894:GOT2
uniprot id: U3JXV9
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

59894:THOC5
gene id: 59894:THOC5
uniprot id: U3JX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

59894:EAF1
gene id: 59894:EAF1
uniprot id: U3K388
names: Similarity
messages: Belongs to the EAF family.

59894:RAD54L2
gene id: 59894:RAD54L2
uniprot id: U3K2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

59894:ST3GAL2
gene id: 59894:ST3GAL2
uniprot id: U3JY67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:TMEM233
gene id: 59894:TMEM233
uniprot id: A0A803VSG9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

59894:NEU4
gene id: 59894:NEU4
uniprot id: A0A803V6Z1
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

59894:ATP6V1H
gene id: 59894:ATP6V1H
uniprot id: U3K6J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

59894:HSPA4
gene id: 59894:HSPA4
uniprot id: U3K2S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

59894:FGFR2
gene id: 59894:FGFR2
uniprot id: A0A803V6C7
uniprot id: A0A803VS65
uniprot id: U3JHI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

59894:GABBR2
gene id: 59894:GABBR2
uniprot id: U3JRI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

59894:CCSER2
gene id: 59894:CCSER2
uniprot id: A0A803VV53
uniprot id: A0A803VVB5
names: Similarity
messages: Belongs to the CCSER family.

59894:MFSD8
gene id: 59894:MFSD8
uniprot id: U3K0B1
names: Subcellular Location Annotation
messages: Membrane

59894:RPL9
gene id: 59894:RPL9
uniprot id: A0A803WC21
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

59894:SEPT7
gene id: 59894:SEPT7
uniprot id: U3JJD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium axoneme
messages: kinetochore
messages: spindle

59894:LOC101811820
gene id: 59894:LOC101811820
uniprot id: U3KKS0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:DDX5
gene id: 59894:DDX5
uniprot id: U3JI17
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

59894:CAPN10
gene id: 59894:CAPN10
uniprot id: U3JZH2
names: Similarity
messages: Belongs to the peptidase C2 family.

59894:BOK
gene id: 59894:BOK
uniprot id: U3JLA0
names: Similarity
messages: Belongs to the Bcl-2 family.

59894:FOXP1
gene id: 59894:FOXP1
uniprot id: U3KG46
names: Subcellular Location Annotation
messages: Nucleus

59894:SLC2A1
gene id: 59894:SLC2A1
uniprot id: U3JMJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane
messages: Photoreceptor inner segment

59894:SGCZ
gene id: 59894:SGCZ
uniprot id: U3JM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

59894:C3H6orf58
gene id: 59894:C3H6orf58
uniprot id: U3KAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

59894:LOC101816697
gene id: 59894:LOC101816697
uniprot id: U3K1G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

59894:FAM163A
gene id: 59894:FAM163A
uniprot id: U3K0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

59894:NBR1
gene id: 59894:NBR1
uniprot id: A0A803V047
uniprot id: U3JDH9
names: Subcellular Location Annotation
messages: autophagosome

59894:FKTN
gene id: 59894:FKTN
uniprot id: U3JJR3
names: Similarity
messages: Belongs to the LicD transferase family.

59894:PSMA7
gene id: 59894:PSMA7
uniprot id: U3K7R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

59894:DCT
gene id: 59894:DCT
uniprot id: U3JPL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

59894:GNG2
gene id: 59894:GNG2
uniprot id: U3JGU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

59894:SLC27A4
gene id: 59894:SLC27A4
uniprot id: U3JF62
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

59894:LOC101815314
gene id: 59894:LOC101815314
uniprot id: U3JUU5
names: Similarity
messages: Belongs to the folate receptor family.

59894:LOC101816251
gene id: 59894:LOC101816251
uniprot id: U3KKR5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:DPT
gene id: 59894:DPT
uniprot id: U3JT48
names: Similarity
messages: Belongs to the dermatopontin family.

59894:LOC101816058
gene id: 59894:LOC101816058
uniprot id: U3K8N5
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101817657
gene id: 59894:LOC101817657
uniprot id: U3K493
names: Similarity
messages: Belongs to the NSG family.

59894:CHD4
gene id: 59894:CHD4
uniprot id: U3JQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

59894:NSMCE2
gene id: 59894:NSMCE2
uniprot id: U3JIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

59894:TXNL4B
gene id: 59894:TXNL4B
uniprot id: A0A803VXP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

59894:NARFL
gene id: 59894:NARFL
uniprot id: A0A803VYJ9
uniprot id: A0A803WGK8
names: Similarity
messages: Belongs to the NARF family.

59894:SLC37A3
gene id: 59894:SLC37A3
uniprot id: U3JM54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

59894:TMBIM4
gene id: 59894:TMBIM4
uniprot id: U3K609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

59894:IQCG
gene id: 59894:IQCG
uniprot id: U3JYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC9 family.
messages: flagellum
messages: flagellum axoneme

59894:SYNJ2
gene id: 59894:SYNJ2
uniprot id: U3KDN4
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

59894:ABCC2
gene id: 59894:ABCC2
uniprot id: U3K0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

59894:KDM3A
gene id: 59894:KDM3A
uniprot id: U3K6B6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

59894:PSMA4
gene id: 59894:PSMA4
uniprot id: A0A803VQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

59894:FAM189A2
gene id: 59894:FAM189A2
uniprot id: U3JQB1
names: Similarity
messages: Belongs to the ENTREP family.

59894:SLC6A15
gene id: 59894:SLC6A15
uniprot id: U3K7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

59894:ZNF711
gene id: 59894:ZNF711
uniprot id: U3JN23
names: Subcellular Location Annotation
messages: Nucleus

59894:GRK7
gene id: 59894:GRK7
uniprot id: U3JWY3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

59894:STX2
gene id: 59894:STX2
uniprot id: A0A803VR47
uniprot id: A0A803W8G9
names: Similarity
messages: Belongs to the syntaxin family.

59894:STAR
gene id: 59894:STAR
uniprot id: U3JW61
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

59894:SDC1
gene id: 59894:SDC1
uniprot id: U3JGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

59894:RPAP1
gene id: 59894:RPAP1
uniprot id: U3JU85
names: Similarity
messages: Belongs to the RPAP1 family.

59894:DOK5
gene id: 59894:DOK5
uniprot id: U3K8T5
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

59894:SPDL1
gene id: 59894:SPDL1
uniprot id: U3K4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spindly family.
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.
messages: kinetochore

59894:MOSPD1
gene id: 59894:MOSPD1
uniprot id: A0A803VDK7
uniprot id: A0A803VWT0
names: Subcellular Location Annotation
messages: Membrane

59894:ACSL1
gene id: 59894:ACSL1
uniprot id: U3KBD1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

59894:TMEM121
gene id: 59894:TMEM121
uniprot id: U3KJC8
names: Similarity
messages: Belongs to the TMEM121 family.

59894:PDXK
gene id: 59894:PDXK
uniprot id: U3KCQ4
names: Similarity
messages: Belongs to the pyridoxine kinase family.

59894:SCN3B
gene id: 59894:SCN3B
uniprot id: U3JT96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

59894:FGFR1OP2
gene id: 59894:FGFR1OP2
uniprot id: A0A803VNA9
names: Similarity
messages: Belongs to the SIKE family.

59894:LOC101820552
gene id: 59894:LOC101820552
uniprot id: A0A803V346
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

59894:HTR2C
gene id: 59894:HTR2C
uniprot id: A0A803VM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:TMPRSS2
gene id: 59894:TMPRSS2
uniprot id: U3JHB8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:ADRA1D
gene id: 59894:ADRA1D
uniprot id: A0A803VWQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

59894:AGT
gene id: 59894:AGT
uniprot id: U3JL95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

59894:LOC101817365
gene id: 59894:LOC101817365
uniprot id: U3KI83
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:HAT1
gene id: 59894:HAT1
uniprot id: A0A803VGF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

59894:TTC39C
gene id: 59894:TTC39C
uniprot id: U3JU90
names: Similarity
messages: Belongs to the TTC39 family.

59894:SOAT1
gene id: 59894:SOAT1
uniprot id: U3K0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:LOC101818173
gene id: 59894:LOC101818173
uniprot id: U3K939
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

59894:LOC101817197
gene id: 59894:LOC101817197
uniprot id: A0A803VNI5
names: Similarity
messages: Belongs to the HEBP family.

59894:WNT8A
gene id: 59894:WNT8A
uniprot id: U3JYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:CDX1
gene id: 59894:CDX1
uniprot id: U3JZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

59894:BCL2
gene id: 59894:BCL2
uniprot id: A0A803VR88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

59894:BPI
gene id: 59894:BPI
uniprot id: U3JRQ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

59894:ADGRG6
gene id: 59894:ADGRG6
uniprot id: U3KE79
uniprot id: U3KE83
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:ALAS1
gene id: 59894:ALAS1
uniprot id: U3K2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

59894:SLC12A3
gene id: 59894:SLC12A3
uniprot id: U3JYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

59894:CCND2
gene id: 59894:CCND2
uniprot id: A0A803VIP2
names: Similarity
messages: Belongs to the cyclin family.

59894:MOV10
gene id: 59894:MOV10
uniprot id: U3JDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

59894:OSTC
gene id: 59894:OSTC
uniprot id: U3KCL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

59894:PDP1
gene id: 59894:PDP1
uniprot id: A0A803UZX3
names: Similarity
messages: Belongs to the PP2C family.

59894:LOC107603309
gene id: 59894:LOC107603309
uniprot id: A0A803V9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

59894:RPL7L1
gene id: 59894:RPL7L1
uniprot id: A0A803V0A7
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

59894:MAFK
gene id: 59894:MAFK
uniprot id: A0A803W4E3
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

59894:MCOLN3
gene id: 59894:MCOLN3
uniprot id: U3JUJ5
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

59894:ADCY8
gene id: 59894:ADCY8
uniprot id: U3JIS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

59894:ABCB6
gene id: 59894:ABCB6
uniprot id: U3JNL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

59894:ALOX5AP
gene id: 59894:ALOX5AP
uniprot id: U3K1F0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:MC3R
gene id: 59894:MC3R
uniprot id: U3KKY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

59894:LOC101813454
gene id: 59894:LOC101813454
uniprot id: U3JPL5
names: Subcellular Location Annotation
messages: Membrane

59894:ECI1
gene id: 59894:ECI1
uniprot id: U3JNM4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

59894:RUVBL1
gene id: 59894:RUVBL1
uniprot id: U3JZN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

59894:CCDC47
gene id: 59894:CCDC47
uniprot id: U3JQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC47 family.
messages: Rough endoplasmic reticulum membrane

59894:MLLT1
gene id: 59894:MLLT1
uniprot id: U3KHB9
names: Subcellular Location Annotation
messages: Nucleus

59894:NCAPD2
gene id: 59894:NCAPD2
uniprot id: A0A803V287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

59894:PDCD11
gene id: 59894:PDCD11
uniprot id: U3K2A0
names: Subcellular Location Annotation
messages: nucleolus

59894:SLC8B1
gene id: 59894:SLC8B1
uniprot id: U3JZ77
names: Subcellular Location Annotation
messages: Membrane

59894:P4HA1
gene id: 59894:P4HA1
uniprot id: A0A803W1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

59894:ABCA2
gene id: 59894:ABCA2
uniprot id: U3JQS4
names: Subcellular Location Annotation
messages: Membrane

59894:VAX1
gene id: 59894:VAX1
uniprot id: A0A803V9Z0
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101817209
gene id: 59894:LOC101817209
uniprot id: U3JGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

59894:NIM1K
gene id: 59894:NIM1K
uniprot id: U3K9C0
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:CKMT2
gene id: 59894:CKMT2
uniprot id: U3KE73
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

59894:TGFBI
gene id: 59894:TGFBI
uniprot id: U3K050
names: Subcellular Location Annotation
messages: extracellular matrix

59894:CTPS1
gene id: 59894:CTPS1
uniprot id: U3JEH3
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

59894:ZBTB8OS
gene id: 59894:ZBTB8OS
uniprot id: U3JCW6
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

59894:CXCR4
gene id: 59894:CXCR4
uniprot id: U3KH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

59894:ATP6AP2
gene id: 59894:ATP6AP2
uniprot id: U3JFQ7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

59894:SDC4
gene id: 59894:SDC4
uniprot id: U3JSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

59894:WNT5B
gene id: 59894:WNT5B
uniprot id: U3JN09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:CD3E
gene id: 59894:CD3E
uniprot id: U3JTY0
names: Subcellular Location Annotation
messages: Membrane

59894:ST6GALNAC6
gene id: 59894:ST6GALNAC6
uniprot id: U3JF16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

59894:VIMP
gene id: 59894:VIMP
uniprot id: U3K6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:NR2F1
gene id: 59894:NR2F1
uniprot id: A0A803VDV8
uniprot id: A0A803W9Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

59894:STX17
gene id: 59894:STX17
uniprot id: A0A803W6Y4
names: Similarity
messages: Belongs to the syntaxin family.

59894:LOC101809294
gene id: 59894:LOC101809294
uniprot id: U3JU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:ZGPAT
gene id: 59894:ZGPAT
uniprot id: U3JTS2
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101821887
gene id: 59894:LOC101821887
uniprot id: A0A803VRX4
uniprot id: U3JJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

59894:SV2B
gene id: 59894:SV2B
uniprot id: U3K737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

59894:ASPH
gene id: 59894:ASPH
uniprot id: A0A803VQG2
uniprot id: A0A803VQQ8
uniprot id: A0A803WH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

59894:RTEL1
gene id: 59894:RTEL1
uniprot id: U3JTN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

59894:CTSC
gene id: 59894:CTSC
uniprot id: U3JZI7
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

59894:OSBPL11
gene id: 59894:OSBPL11
uniprot id: U3KGG6
names: Similarity
messages: Belongs to the OSBP family.

59894:SUMF2
gene id: 59894:SUMF2
uniprot id: U3JWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

59894:TMEM150C
gene id: 59894:TMEM150C
uniprot id: A0A803VH62
names: Subcellular Location Annotation
messages: Membrane

59894:SDAD1
gene id: 59894:SDAD1
uniprot id: U3K166
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

59894:BRIX1
gene id: 59894:BRIX1
uniprot id: U3JHD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

59894:ROS1
gene id: 59894:ROS1
uniprot id: U3K981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

59894:AGPAT5
gene id: 59894:AGPAT5
uniprot id: A0A803VKD5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

59894:SEC24D
gene id: 59894:SEC24D
uniprot id: U3JDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

59894:BDKRB2
gene id: 59894:BDKRB2
uniprot id: U3KK45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

59894:ATP6V1D
gene id: 59894:ATP6V1D
uniprot id: U3JRT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

59894:DERL1
gene id: 59894:DERL1
uniprot id: U3JID9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

59894:MTHFR
gene id: 59894:MTHFR
uniprot id: U3K671
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

59894:ALDH1A3
gene id: 59894:ALDH1A3
uniprot id: U3K6Q3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

59894:LOC101819243
gene id: 59894:LOC101819243
uniprot id: U3KID7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

59894:DRD1
gene id: 59894:DRD1
uniprot id: U3KJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LOC101817870
gene id: 59894:LOC101817870
uniprot id: U3JZB6
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:NAA35
gene id: 59894:NAA35
uniprot id: U3JLU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

59894:LOC101806066
gene id: 59894:LOC101806066
uniprot id: U3JZ87
names: Similarity
messages: Belongs to the DCK/DGK family.

59894:LRRC8A
gene id: 59894:LRRC8A
uniprot id: U3JFD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

59894:SERINC5
gene id: 59894:SERINC5
uniprot id: A0A803WGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

59894:RNF121
gene id: 59894:RNF121
uniprot id: A0A803VK41
names: Subcellular Location Annotation
messages: Membrane

59894:NCOR2
gene id: 59894:NCOR2
uniprot id: U3K414
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

59894:PLA1A
gene id: 59894:PLA1A
uniprot id: U3JS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

59894:BRD1
gene id: 59894:BRD1
uniprot id: U3K4S9
names: Subcellular Location Annotation
messages: Nucleus

59894:ITFG1
gene id: 59894:ITFG1
uniprot id: U3JBH9
names: Similarity
messages: Belongs to the TIP family.

59894:LOC101811535
gene id: 59894:LOC101811535
uniprot id: U3KKU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

59894:HTR1B
gene id: 59894:HTR1B
uniprot id: U3KJS0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1D.
messages: Membrane

59894:MAEL
gene id: 59894:MAEL
uniprot id: U3JFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

59894:FAM120A
gene id: 59894:FAM120A
uniprot id: A0A803VQM8
uniprot id: U3JX26
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

59894:EFTUD2
gene id: 59894:EFTUD2
uniprot id: U3JYM2
names: Subcellular Location Annotation
messages: Nucleus

59894:PTDSS1
gene id: 59894:PTDSS1
uniprot id: U3JSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:MRAP2
gene id: 59894:MRAP2
uniprot id: U3JJC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:DNAJC24
gene id: 59894:DNAJC24
uniprot id: A0A803VTH6
names: Similarity
messages: Belongs to the DPH4 family.

59894:PPAT
gene id: 59894:PPAT
uniprot id: A0A803VDM4
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

59894:NCOA3
gene id: 59894:NCOA3
uniprot id: U3KEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

59894:POLR3H
gene id: 59894:POLR3H
uniprot id: U3KBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

59894:LOC101807050
gene id: 59894:LOC101807050
uniprot id: A0A803V5B1
uniprot id: U3K8T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

59894:PPIH
gene id: 59894:PPIH
uniprot id: U3K6T2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

59894:SEC11A
gene id: 59894:SEC11A
uniprot id: U3K5N4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:FABP5
gene id: 59894:FABP5
uniprot id: U3K1U5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:XG
gene id: 59894:XG
uniprot id: U3JNK4
names: Similarity
messages: Belongs to the CD99 family.

59894:SLC6A17
gene id: 59894:SLC6A17
uniprot id: A0A803VLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:TARS
gene id: 59894:TARS
uniprot id: U3JHG2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

59894:NMUR2
gene id: 59894:NMUR2
uniprot id: U3K0R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

59894:C1S
gene id: 59894:C1S
uniprot id: U3JPU3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:USP18
gene id: 59894:USP18
uniprot id: U3K4Q5
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:LOC101808993
gene id: 59894:LOC101808993
uniprot id: U3JRL8
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

59894:LOC101812529
gene id: 59894:LOC101812529
uniprot id: A0A803WGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

59894:GPBP1L1
gene id: 59894:GPBP1L1
uniprot id: U3K4K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

59894:ZIC1
gene id: 59894:ZIC1
uniprot id: U3JX97
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

59894:RPA1
gene id: 59894:RPA1
uniprot id: U3JVR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

59894:STX12
gene id: 59894:STX12
uniprot id: A0A803VGP8
names: Similarity
messages: Belongs to the syntaxin family.

59894:CNOT8
gene id: 59894:CNOT8
uniprot id: U3K0Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

59894:OCSTAMP
gene id: 59894:OCSTAMP
uniprot id: A0A803VJ74
names: Subcellular Location Annotation
messages: Membrane

59894:USP2
gene id: 59894:USP2
uniprot id: U3JU75
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:AP3M2
gene id: 59894:AP3M2
uniprot id: U3JV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

59894:SLC1A2
gene id: 59894:SLC1A2
uniprot id: U3KDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

59894:C1H11orf70
gene id: 59894:C1H11orf70
uniprot id: U3JC63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

59894:RNF182
gene id: 59894:RNF182
uniprot id: U3KK90
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

59894:LOC101807822
gene id: 59894:LOC101807822
uniprot id: U3K094
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

59894:USMG5
gene id: 59894:USMG5
uniprot id: U3K298
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

59894:LOC101817073
gene id: 59894:LOC101817073
uniprot id: A0A803WC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

59894:FUCA2
gene id: 59894:FUCA2
uniprot id: U3KE10
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

59894:STAG2
gene id: 59894:STAG2
uniprot id: A0A803V0E6
uniprot id: A0A803V9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

59894:TATDN1
gene id: 59894:TATDN1
uniprot id: U3JIM3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

59894:CLCN6
gene id: 59894:CLCN6
uniprot id: A0A803V8L6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:MRPS6
gene id: 59894:MRPS6
uniprot id: U3JR92
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

59894:GLYCTK
gene id: 59894:GLYCTK
uniprot id: A0A803WGT1
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

59894:WDPCP
gene id: 59894:WDPCP
uniprot id: U3KGN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

59894:LOC101816877
gene id: 59894:LOC101816877
uniprot id: A0A803W4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

59894:SPI1
gene id: 59894:SPI1
uniprot id: A0A803W3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:PTRF
gene id: 59894:PTRF
uniprot id: U3JD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

59894:DLL4
gene id: 59894:DLL4
uniprot id: U3JUE3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

59894:OSBPL8
gene id: 59894:OSBPL8
uniprot id: A0A803VEW4
uniprot id: A0A803W996
names: Similarity
messages: Belongs to the OSBP family.

59894:PGK1
gene id: 59894:PGK1
uniprot id: U3K8X2
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

59894:C26H6orf89
gene id: 59894:C26H6orf89
uniprot id: U3JKW6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

59894:SENP5
gene id: 59894:SENP5
uniprot id: U3K0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

59894:FPGS
gene id: 59894:FPGS
uniprot id: U3JF34
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

59894:ARL6IP5
gene id: 59894:ARL6IP5
uniprot id: A0A803VTP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

59894:ROMO1
gene id: 59894:ROMO1
uniprot id: U3KDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

59894:RIN3
gene id: 59894:RIN3
uniprot id: U3JID2
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

59894:TSHZ2
gene id: 59894:TSHZ2
uniprot id: A0A803V9D1
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

59894:STAT6
gene id: 59894:STAT6
uniprot id: U3JC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

59894:MAFG
gene id: 59894:MAFG
uniprot id: A0A803VYL3
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

59894:SSX2IP
gene id: 59894:SSX2IP
uniprot id: U3JUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

59894:APITD1
gene id: 59894:APITD1
uniprot id: U3JXN6
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

59894:MYO7B
gene id: 59894:MYO7B
uniprot id: U3KGL7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

59894:REXO2
gene id: 59894:REXO2
uniprot id: U3K622
names: Similarity
messages: Belongs to the oligoribonuclease family.

59894:KCNV2
gene id: 59894:KCNV2
uniprot id: U3K7F7
names: Subcellular Location Annotation
messages: Membrane

59894:ABCG2
gene id: 59894:ABCG2
uniprot id: U3JRH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

59894:LOC101816669
gene id: 59894:LOC101816669
uniprot id: U3K663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

59894:FBLN1
gene id: 59894:FBLN1
uniprot id: U3JJJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

59894:LOC101807523
gene id: 59894:LOC101807523
uniprot id: A0A803VXE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

59894:RAB3GAP2
gene id: 59894:RAB3GAP2
uniprot id: U3KC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP regulatory subunit family.
messages: Cytoplasm

59894:PPP1CB
gene id: 59894:PPP1CB
uniprot id: A0A803V127
uniprot id: A0A803W9V5
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

59894:SCN4A
gene id: 59894:SCN4A
uniprot id: U3KGZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

59894:ZDHHC7
gene id: 59894:ZDHHC7
uniprot id: A0A803V6K2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:TRPC1
gene id: 59894:TRPC1
uniprot id: U3JX68
names: Subcellular Location Annotation
messages: Membrane

59894:GLRB
gene id: 59894:GLRB
uniprot id: A0A803W5F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

59894:CTDP1
gene id: 59894:CTDP1
uniprot id: U3KFV6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

59894:GAB3
gene id: 59894:GAB3
uniprot id: U3JBQ6
names: Similarity
messages: Belongs to the GAB family.

59894:TMEM144
gene id: 59894:TMEM144
uniprot id: A0A803VPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

59894:RRM2B
gene id: 59894:RRM2B
uniprot id: U3JTN7
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

59894:TRPM2
gene id: 59894:TRPM2
uniprot id: U3JKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

59894:STT3A
gene id: 59894:STT3A
uniprot id: U3JRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

59894:MLF2
gene id: 59894:MLF2
uniprot id: U3JQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

59894:SLC43A3
gene id: 59894:SLC43A3
uniprot id: U3K9L7
names: Subcellular Location Annotation
messages: Membrane

59894:LPAR5
gene id: 59894:LPAR5
uniprot id: U3KJF1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:ELMO2
gene id: 59894:ELMO2
uniprot id: U3JQK7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

59894:FAM214A
gene id: 59894:FAM214A
uniprot id: U3KBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

59894:UNC5A
gene id: 59894:UNC5A
uniprot id: U3K1V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

59894:PKIB
gene id: 59894:PKIB
uniprot id: A0A803W361
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

59894:LOC101817249
gene id: 59894:LOC101817249
uniprot id: U3JDR2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

59894:ERRFI1
gene id: 59894:ERRFI1
uniprot id: A0A803W1X3
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

59894:PTPN6
gene id: 59894:PTPN6
uniprot id: A0A803VH52
uniprot id: A0A803W6U4
uniprot id: U3JPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

59894:ZDHHC22
gene id: 59894:ZDHHC22
uniprot id: A0A803V2E1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

59894:ASCC1
gene id: 59894:ASCC1
uniprot id: U3KDX1
names: Subcellular Location Annotation
messages: Cytoplasm

59894:MATK
gene id: 59894:MATK
uniprot id: A0A803V1L1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:CZH18orf32
gene id: 59894:CZH18orf32
uniprot id: U3K2U3
names: Similarity
messages: Belongs to the UPF0729 family.

59894:MRPL53
gene id: 59894:MRPL53
uniprot id: A0A803W869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

59894:ABCC8
gene id: 59894:ABCC8
uniprot id: U3JDE3
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

59894:RAB3IP
gene id: 59894:RAB3IP
uniprot id: U3K6K8
names: Similarity
messages: Belongs to the SEC2 family.

59894:FAM175B
gene id: 59894:FAM175B
uniprot id: A0A803V623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

59894:CLCC1
gene id: 59894:CLCC1
uniprot id: U3JJ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane

59894:UBE2H
gene id: 59894:UBE2H
uniprot id: A0A803WF16
uniprot id: U3JQY8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

59894:N4BP3
gene id: 59894:N4BP3
uniprot id: U3K293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Vesicle
messages: dendrite

59894:MMP7
gene id: 59894:MMP7
uniprot id: U3JC75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

59894:RIBC2
gene id: 59894:RIBC2
uniprot id: U3JJI7
names: Similarity
messages: Belongs to the RIB43A family.

59894:HRH2
gene id: 59894:HRH2
uniprot id: U3K1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:ARHGEF6
gene id: 59894:ARHGEF6
uniprot id: U3JMA9
names: Subcellular Location Annotation
messages: lamellipodium

59894:DPM1
gene id: 59894:DPM1
uniprot id: U3KF01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

59894:SLC6A7
gene id: 59894:SLC6A7
uniprot id: U3JZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

59894:TMEM9
gene id: 59894:TMEM9
uniprot id: U3JIJ0
names: Similarity
messages: Belongs to the TMEM9 family.

59894:CHD7
gene id: 59894:CHD7
uniprot id: U3JST3
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

59894:ITPRIP
gene id: 59894:ITPRIP
uniprot id: U3KL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

59894:SLC2A9
gene id: 59894:SLC2A9
uniprot id: U3K427
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:RPL36
gene id: 59894:RPL36
uniprot id: U3KBT7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

59894:NDUFA8
gene id: 59894:NDUFA8
uniprot id: A0A803V4M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

59894:ARL1
gene id: 59894:ARL1
uniprot id: U3K9E2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

59894:HSPA5
gene id: 59894:HSPA5
uniprot id: U3JHL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

59894:GORASP1
gene id: 59894:GORASP1
uniprot id: A0A803V3T7
names: Similarity
messages: Belongs to the GORASP family.

59894:LOC101809373
gene id: 59894:LOC101809373
uniprot id: A0A803VFE4
names: Subcellular Location Annotation
messages: Membrane

59894:GJA9
gene id: 59894:GJA9
uniprot id: U3KIP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:UBA6
gene id: 59894:UBA6
uniprot id: U3JVS9
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

59894:ARRDC3
gene id: 59894:ARRDC3
uniprot id: U3K354
names: Similarity
messages: Belongs to the arrestin family.

59894:ZNF488
gene id: 59894:ZNF488
uniprot id: A0A803WE74
names: Subcellular Location Annotation
messages: Nucleus

59894:AURKAIP1
gene id: 59894:AURKAIP1
uniprot id: A0A803VPL9
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

59894:NMUR1
gene id: 59894:NMUR1
uniprot id: U3JYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

59894:LRRFIP1
gene id: 59894:LRRFIP1
uniprot id: A0A803V4N4
uniprot id: A0A803VR93
uniprot id: A0A803WBK8
uniprot id: A0A803WC85
names: Similarity
messages: Belongs to the LRRFIP family.

59894:NDUFS1
gene id: 59894:NDUFS1
uniprot id: U3JMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

59894:FAM63B
gene id: 59894:FAM63B
uniprot id: U3KCQ5
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

59894:ATP7A
gene id: 59894:ATP7A
uniprot id: U3K8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

59894:IMPA1
gene id: 59894:IMPA1
uniprot id: U3K1U8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

59894:OSBPL3
gene id: 59894:OSBPL3
uniprot id: U3K4K8
names: Similarity
messages: Belongs to the OSBP family.

59894:MFSD10
gene id: 59894:MFSD10
uniprot id: U3K5C1
names: Subcellular Location Annotation
messages: Membrane

59894:THBS2
gene id: 59894:THBS2
uniprot id: U3JKF0
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:C8B
gene id: 59894:C8B
uniprot id: U3KCU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:TMEM184A
gene id: 59894:TMEM184A
uniprot id: U3KHL7
names: Subcellular Location Annotation
messages: Membrane

59894:SCML4
gene id: 59894:SCML4
uniprot id: U3KB42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

59894:IL7R
gene id: 59894:IL7R
uniprot id: U3JHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
messages: The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

59894:LOC101814452
gene id: 59894:LOC101814452
uniprot id: U3JRA1
names: Similarity
messages: Belongs to the peptidase M14 family.

59894:MUT
gene id: 59894:MUT
uniprot id: U3KE18
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

59894:ALB
gene id: 59894:ALB
uniprot id: U3K0R0
names: Subcellular Location Annotation
messages: Secreted

59894:P2RX3
gene id: 59894:P2RX3
uniprot id: U3K9X5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

59894:TSEN15
gene id: 59894:TSEN15
uniprot id: U3JKD0
names: Similarity
messages: Belongs to the SEN15 family.

59894:BICD2
gene id: 59894:BICD2
uniprot id: A0A803VM33
names: Similarity
messages: Belongs to the BicD family.

59894:ACTN1
gene id: 59894:ACTN1
uniprot id: A0A803V8Q4
uniprot id: A0A803VS66
uniprot id: U3JR83
names: Similarity
messages: Belongs to the alpha-actinin family.

59894:ASIP
gene id: 59894:ASIP
uniprot id: A0A803VWB4
names: Subcellular Location Annotation
messages: Secreted

59894:KCNB1
gene id: 59894:KCNB1
uniprot id: A0A803VWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: dendrite
messages: sarcolemma
messages: synaptosome

59894:LOC101814802
gene id: 59894:LOC101814802
uniprot id: U3KC12
names: Similarity
messages: Belongs to the peptidase A1 family.

59894:KLHL15
gene id: 59894:KLHL15
uniprot id: A0A803W3Y2
names: Subcellular Location Annotation
messages: Nucleus

59894:PIK3CD
gene id: 59894:PIK3CD
uniprot id: U3JXY4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

59894:LDLRAD4
gene id: 59894:LDLRAD4
uniprot id: A0A803V8Y5
uniprot id: A0A803VUP0
uniprot id: A0A803WCV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:PDE7A
gene id: 59894:PDE7A
uniprot id: A0A803WBN4
uniprot id: U3JSD0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:PRDM16
gene id: 59894:PRDM16
uniprot id: U3K4P4
names: Subcellular Location Annotation
messages: Nucleus

59894:ATIC
gene id: 59894:ATIC
uniprot id: U3KEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

59894:LOC101810921
gene id: 59894:LOC101810921
uniprot id: U3KKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:CLDN19
gene id: 59894:CLDN19
uniprot id: U3K6W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:USP44
gene id: 59894:USP44
uniprot id: U3K8A2
names: Similarity
messages: Belongs to the peptidase C19 family.

59894:INTS2
gene id: 59894:INTS2
uniprot id: U3JSH9
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

59894:RRM1
gene id: 59894:RRM1
uniprot id: U3K6Q9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

59894:GLI3
gene id: 59894:GLI3
uniprot id: U3JRB6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

59894:KIF24
gene id: 59894:KIF24
uniprot id: A0A803W994
uniprot id: U3K5K1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

59894:CEPT1
gene id: 59894:CEPT1
uniprot id: A0A803VIZ5
uniprot id: A0A803VRX7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

59894:MRPL41
gene id: 59894:MRPL41
uniprot id: U3KJZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

59894:HYOU1
gene id: 59894:HYOU1
uniprot id: U3K5I9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

59894:LOC101808185
gene id: 59894:LOC101808185
uniprot id: U3JFJ7
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

59894:ATP6V0A2
gene id: 59894:ATP6V0A2
uniprot id: U3K3W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

59894:HARBI1
gene id: 59894:HARBI1
uniprot id: A0A803VN74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

59894:LOC101815822
gene id: 59894:LOC101815822
uniprot id: A0A803V927
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

59894:GPLD1
gene id: 59894:GPLD1
uniprot id: U3KGH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPLD1 family.
messages: Secreted

59894:APAF1
gene id: 59894:APAF1
uniprot id: U3K8W9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Monomer. Oligomerizes upon binding of cytochrome c and dATP.
messages: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.

59894:STARD3NL
gene id: 59894:STARD3NL
uniprot id: U3JJL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

59894:DTNBP1
gene id: 59894:DTNBP1
uniprot id: U3KG51
names: Similarity
messages: Belongs to the dysbindin family.

59894:PCK1
gene id: 59894:PCK1
uniprot id: A0A803VVV7
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

59894:LOC101812619
gene id: 59894:LOC101812619
uniprot id: U3KKV4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

59894:SLC43A2
gene id: 59894:SLC43A2
uniprot id: U3JVX8
names: Subcellular Location Annotation
messages: Membrane

59894:SAMD8
gene id: 59894:SAMD8
uniprot id: U3JWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

59894:LOC101819452
gene id: 59894:LOC101819452
uniprot id: U3JH19
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

59894:GAL3ST2
gene id: 59894:GAL3ST2
uniprot id: A0A803V1X9
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

59894:CLCF1
gene id: 59894:CLCF1
uniprot id: U3KCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

59894:MAST4
gene id: 59894:MAST4
uniprot id: A0A803VIC0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

59894:CHAT
gene id: 59894:CHAT
uniprot id: U3JWD1
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

59894:SLCO1A2
gene id: 59894:SLCO1A2
uniprot id: A0A803W175
uniprot id: U3K039
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:MINA
gene id: 59894:MINA
uniprot id: A0A803VP40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

59894:KLC4
gene id: 59894:KLC4
uniprot id: A0A803V3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

59894:CDH6
gene id: 59894:CDH6
uniprot id: U3KEA4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:TXNL4A
gene id: 59894:TXNL4A
uniprot id: U3KFU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

59894:HRH1
gene id: 59894:HRH1
uniprot id: U3KIB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:CLDN16
gene id: 59894:CLDN16
uniprot id: U3JY20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

59894:LOC101819625
gene id: 59894:LOC101819625
uniprot id: U3JUN0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

59894:THRSP
gene id: 59894:THRSP
uniprot id: U3KKR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

59894:IQCD
gene id: 59894:IQCD
uniprot id: U3JWP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC10 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
messages: flagellum axoneme

59894:LYRM1
gene id: 59894:LYRM1
uniprot id: A0A803W3N3
names: Similarity
messages: Belongs to the complex I LYR family.

59894:LOC101818100
gene id: 59894:LOC101818100
uniprot id: U3K7C5
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:LOC101813221
gene id: 59894:LOC101813221
uniprot id: U3JK79
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:GOLT1A
gene id: 59894:GOLT1A
uniprot id: U3JCE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

59894:KPNA5
gene id: 59894:KPNA5
uniprot id: U3K917
names: Similarity
messages: Belongs to the importin alpha family.

59894:LOC101820708
gene id: 59894:LOC101820708
uniprot id: U3JMU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 23 family.
messages: Secreted

59894:TTC12
gene id: 59894:TTC12
uniprot id: A0A803VZE6
uniprot id: U3JBV7
names: Subcellular Location Annotation
messages: A band
messages: Z line

59894:RC3H1
gene id: 59894:RC3H1
uniprot id: U3JJY9
names: Subcellular Location Annotation
messages: P-body

59894:TOM1L1
gene id: 59894:TOM1L1
uniprot id: U3JHU9
names: Similarity
messages: Belongs to the TOM1 family.

59894:NSDHL
gene id: 59894:NSDHL
uniprot id: U3KA43
names: Similarity
messages: Belongs to the 3-beta-HSD family.

59894:SLC1A7
gene id: 59894:SLC1A7
uniprot id: U3JT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

59894:FSHB
gene id: 59894:FSHB
uniprot id: A0A803W6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

59894:RAMP1
gene id: 59894:RAMP1
uniprot id: A0A803V565
names: Similarity
messages: Belongs to the RAMP family.

59894:PCNA
gene id: 59894:PCNA
uniprot id: U3JBU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

59894:NIPBL
gene id: 59894:NIPBL
uniprot id: A0A803VM48
uniprot id: U3JH84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

59894:GABRA3
gene id: 59894:GABRA3
uniprot id: A0A803VQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:LOC101808676
gene id: 59894:LOC101808676
uniprot id: A0A803W7E2
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:KARS
gene id: 59894:KARS
uniprot id: U3JIR9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

59894:TTC27
gene id: 59894:TTC27
uniprot id: U3KBX5
names: Similarity
messages: Belongs to the TTC27 family.

59894:SLC35A5
gene id: 59894:SLC35A5
uniprot id: U3JTI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

59894:LOC101810165
gene id: 59894:LOC101810165
uniprot id: U3KEY0
names: Similarity
messages: Belongs to the serpin family.

59894:LRRCC1
gene id: 59894:LRRCC1
uniprot id: U3JQM6
names: Similarity
messages: Belongs to the SDS22 family.

59894:MMD2
gene id: 59894:MMD2
uniprot id: U3KHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

59894:LPIN2
gene id: 59894:LPIN2
uniprot id: U3JUW6
names: Similarity
messages: Belongs to the lipin family.

59894:GIMD1
gene id: 59894:GIMD1
uniprot id: U3KCY5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

59894:OLFM3
gene id: 59894:OLFM3
uniprot id: A0A803VLU1
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

59894:P2RY8
gene id: 59894:P2RY8
uniprot id: U3KKT0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:PMM2
gene id: 59894:PMM2
uniprot id: U3JN15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

59894:STX7
gene id: 59894:STX7
uniprot id: U3KBB5
names: Similarity
messages: Belongs to the syntaxin family.

59894:ADRB1
gene id: 59894:ADRB1
uniprot id: U3JHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LOC101818535
gene id: 59894:LOC101818535
uniprot id: U3KHV8
names: Similarity
messages: Belongs to the 3-beta-HSD family.

59894:SMDT1
gene id: 59894:SMDT1
uniprot id: U3KB44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

59894:SLC22A2
gene id: 59894:SLC22A2
uniprot id: U3KBU9
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

59894:SLC9A3
gene id: 59894:SLC9A3
uniprot id: A0A803VKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

59894:FAP
gene id: 59894:FAP
uniprot id: U3JD75
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

59894:AMT
gene id: 59894:AMT
uniprot id: U3K304
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

59894:RIOK3
gene id: 59894:RIOK3
uniprot id: U3JUF5
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

59894:MPP3
gene id: 59894:MPP3
uniprot id: U3JDK7
names: Similarity
messages: Belongs to the MAGUK family.

59894:RPS8
gene id: 59894:RPS8
uniprot id: U3JRK7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

59894:DGKG
gene id: 59894:DGKG
uniprot id: U3JL51
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

59894:EIF4H
gene id: 59894:EIF4H
uniprot id: A0A803VGS1
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

59894:DAP3
gene id: 59894:DAP3
uniprot id: U3JJK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

59894:ENTPD6
gene id: 59894:ENTPD6
uniprot id: U3JDA9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

59894:FAM83B
gene id: 59894:FAM83B
uniprot id: U3JGK8
names: Similarity
messages: Belongs to the FAM83 family.

59894:CDH19
gene id: 59894:CDH19
uniprot id: U3JVU7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:GLUL
gene id: 59894:GLUL
uniprot id: U3JZZ9
names: Similarity
messages: Belongs to the glutamine synthetase family.

59894:GMNN
gene id: 59894:GMNN
uniprot id: A0A803W2B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

59894:WTAP
gene id: 59894:WTAP
uniprot id: A0A803VCK8
names: Similarity
messages: Belongs to the fl(2)d family.

59894:LOC101820160
gene id: 59894:LOC101820160
uniprot id: U3K1I4
names: Similarity
messages: Belongs to the TASOR family.

59894:TOP3B
gene id: 59894:TOP3B
uniprot id: U3JZQ9
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

59894:PITPNM2
gene id: 59894:PITPNM2
uniprot id: A0A803VQ82
uniprot id: A0A803VX65
uniprot id: A0A803WA08
uniprot id: U3K3P2
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

59894:TNFAIP6
gene id: 59894:TNFAIP6
uniprot id: U3KHH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:PDP2
gene id: 59894:PDP2
uniprot id: U3KIV8
names: Similarity
messages: Belongs to the PP2C family.

59894:THYN1
gene id: 59894:THYN1
uniprot id: U3JT00
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

59894:MMAA
gene id: 59894:MMAA
uniprot id: A0A803V5Y4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

59894:SPC25
gene id: 59894:SPC25
uniprot id: A0A803W1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

59894:THAP1
gene id: 59894:THAP1
uniprot id: U3JRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

59894:GABARAPL2
gene id: 59894:GABARAPL2
uniprot id: U3JIL3
names: Similarity
messages: Belongs to the ATG8 family.

59894:CTSL
gene id: 59894:CTSL
uniprot id: A0A803VMR0
names: Similarity
messages: Belongs to the peptidase C1 family.

59894:L3MBTL2
gene id: 59894:L3MBTL2
uniprot id: A0A803VEE4
uniprot id: U3KC09
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.
messages: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

59894:LOC101818444
gene id: 59894:LOC101818444
uniprot id: A0A803W4T2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:ACAA1
gene id: 59894:ACAA1
uniprot id: U3JVR3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

59894:LOC101808769
gene id: 59894:LOC101808769
uniprot id: U3KJB0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:GABARAPL1
gene id: 59894:GABARAPL1
uniprot id: U3JLZ6
names: Similarity
messages: Belongs to the ATG8 family.

59894:ACER1
gene id: 59894:ACER1
uniprot id: A0A803V5J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

59894:LOC107603324
gene id: 59894:LOC107603324
uniprot id: U3JXL2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

59894:VPS4B
gene id: 59894:VPS4B
uniprot id: A0A803V9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

59894:DZIP1
gene id: 59894:DZIP1
uniprot id: U3JPG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

59894:UPP1
gene id: 59894:UPP1
uniprot id: U3JYD8
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

59894:NCOA2
gene id: 59894:NCOA2
uniprot id: U3K118
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

59894:SIGIRR
gene id: 59894:SIGIRR
uniprot id: U3KAK0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

59894:TUBA8
gene id: 59894:TUBA8
uniprot id: U3K4R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

59894:CEP162
gene id: 59894:CEP162
uniprot id: A0A803VI47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

59894:LOC101808357
gene id: 59894:LOC101808357
uniprot id: U3JXA2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

59894:LOC101819083
gene id: 59894:LOC101819083
uniprot id: U3KIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

59894:AS3MT
gene id: 59894:AS3MT
uniprot id: A0A803VCA5
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

59894:PLD4
gene id: 59894:PLD4
uniprot id: A0A803WET2
uniprot id: U3JK22
names: Similarity
messages: Belongs to the phospholipase D family.

59894:PTK2
gene id: 59894:PTK2
uniprot id: U3JJM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

59894:NEIL2
gene id: 59894:NEIL2
uniprot id: U3JIK9
names: Similarity
messages: Belongs to the FPG family.

59894:ECHDC2
gene id: 59894:ECHDC2
uniprot id: U3JSX2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

59894:ENSA
gene id: 59894:ENSA
uniprot id: A0A803VUQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

59894:IL13RA2
gene id: 59894:IL13RA2
uniprot id: A0A803VR09
names: Subcellular Location Annotation
messages: Membrane

59894:SLC24A5
gene id: 59894:SLC24A5
uniprot id: U3KAN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

59894:GCSH
gene id: 59894:GCSH
uniprot id: U3JWH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

59894:MPPED1
gene id: 59894:MPPED1
uniprot id: A0A803VW19
names: Similarity
messages: Belongs to the UPF0046 family.

59894:GPSM2
gene id: 59894:GPSM2
uniprot id: U3JJ45
names: Similarity
messages: Belongs to the GPSM family.

59894:KCNAB2
gene id: 59894:KCNAB2
uniprot id: U3K533
uniprot id: U3K536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

59894:INSIG1
gene id: 59894:INSIG1
uniprot id: A0A803W7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

59894:KANSL2
gene id: 59894:KANSL2
uniprot id: U3JBH3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

59894:CDC123
gene id: 59894:CDC123
uniprot id: A0A803V3J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

59894:CD40LG
gene id: 59894:CD40LG
uniprot id: A0A803V9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

59894:CELF1
gene id: 59894:CELF1
uniprot id: A0A803WDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

59894:HMGN5
gene id: 59894:HMGN5
uniprot id: U3JN83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

59894:DNM3
gene id: 59894:DNM3
uniprot id: A0A803V9V3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

59894:STAM2
gene id: 59894:STAM2
uniprot id: A0A803W9G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

59894:CDK1
gene id: 59894:CDK1
uniprot id: U3KFU5
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:HSPA14
gene id: 59894:HSPA14
uniprot id: U3JGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

59894:LOC101814354
gene id: 59894:LOC101814354
uniprot id: U3KF64
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

59894:EXOSC1
gene id: 59894:EXOSC1
uniprot id: U3K1A1
names: Subcellular Location Annotation
messages: Cytoplasm

59894:LOC101815246
gene id: 59894:LOC101815246
uniprot id: U3JNH1
names: Subcellular Location Annotation
messages: Membrane

59894:ATP2B1
gene id: 59894:ATP2B1
uniprot id: A0A803W301
uniprot id: U3K7U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:FASN
gene id: 59894:FASN
uniprot id: U3KB05
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

59894:LACC1
gene id: 59894:LACC1
uniprot id: U3K0C8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

59894:LOC101809150
gene id: 59894:LOC101809150
uniprot id: A0A803W6D5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:PAH
gene id: 59894:PAH
uniprot id: U3K3A9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

59894:GTF2E1
gene id: 59894:GTF2E1
uniprot id: U3JRU8
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

59894:GNPDA1
gene id: 59894:GNPDA1
uniprot id: A0A803V6X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

59894:C28H19orf24
gene id: 59894:C28H19orf24
uniprot id: U3KHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

59894:LAMP2
gene id: 59894:LAMP2
uniprot id: A0A803WD13
uniprot id: U3JFP7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

59894:FAM221A
gene id: 59894:FAM221A
uniprot id: U3K4P6
names: Similarity
messages: Belongs to the FAM221 family.

59894:AASDH
gene id: 59894:AASDH
uniprot id: A0A803W1R3
uniprot id: A0A803WE17
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

59894:DTX2
gene id: 59894:DTX2
uniprot id: U3K4M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

59894:CLSTN3
gene id: 59894:CLSTN3
uniprot id: U3JPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

59894:NNT
gene id: 59894:NNT
uniprot id: U3K9H5
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

59894:RBKS
gene id: 59894:RBKS
uniprot id: U3K8E6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

59894:SLC25A37
gene id: 59894:SLC25A37
uniprot id: U3K994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

59894:LOC101816948
gene id: 59894:LOC101816948
uniprot id: U3JRK3
names: Similarity
messages: Belongs to the cornifelin family.

59894:MIOS
gene id: 59894:MIOS
uniprot id: U3K6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

59894:KCNF1
gene id: 59894:KCNF1
uniprot id: U3KJN8
names: Subcellular Location Annotation
messages: Membrane

59894:MAS1
gene id: 59894:MAS1
uniprot id: U3KLQ4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:CRABP1
gene id: 59894:CRABP1
uniprot id: U3K7U2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

59894:SNX20
gene id: 59894:SNX20
uniprot id: U3JBC8
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

59894:SLC9A9
gene id: 59894:SLC9A9
uniprot id: U3JX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

59894:HOMER1
gene id: 59894:HOMER1
uniprot id: U3K5M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

59894:ABCG4
gene id: 59894:ABCG4
uniprot id: U3JUB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

59894:RPL31
gene id: 59894:RPL31
uniprot id: U3JMH0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

59894:DDO
gene id: 59894:DDO
uniprot id: A0A803VZ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

59894:SIN3B
gene id: 59894:SIN3B
uniprot id: U3KHH1
names: Subcellular Location Annotation
messages: Nucleus

59894:GDPD2
gene id: 59894:GDPD2
uniprot id: U3KC25
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

59894:EIF3I
gene id: 59894:EIF3I
uniprot id: A0A803VD57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

59894:BRF1
gene id: 59894:BRF1
uniprot id: A0A803V409
names: Similarity
messages: Belongs to the TFIIB family.

59894:GNG12
gene id: 59894:GNG12
uniprot id: U3KEP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

59894:SSH2
gene id: 59894:SSH2
uniprot id: A0A803VBF8
uniprot id: U3JUP1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

59894:SETD3
gene id: 59894:SETD3
uniprot id: U3JIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

59894:LOC101819725
gene id: 59894:LOC101819725
uniprot id: A0A803W5D6
names: Similarity
messages: Belongs to the histone H2B family.

59894:FMN2
gene id: 59894:FMN2
uniprot id: A0A803VW23
uniprot id: U3KFG0
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

59894:LOC101817697
gene id: 59894:LOC101817697
uniprot id: A0A803VKF9
names: Similarity
messages: Belongs to the 3-beta-HSD family.

59894:MRPS25
gene id: 59894:MRPS25
uniprot id: U3KGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

59894:TMEM198
gene id: 59894:TMEM198
uniprot id: U3JNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

59894:SLC12A9
gene id: 59894:SLC12A9
uniprot id: U3JZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

59894:CTGF
gene id: 59894:CTGF
uniprot id: U3KB68
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:HOXA7
gene id: 59894:HOXA7
uniprot id: A0A803WEB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

59894:LOC101811458
gene id: 59894:LOC101811458
uniprot id: U3JMT9
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:PKNOX1
gene id: 59894:PKNOX1
uniprot id: U3JGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

59894:LOC101820945
gene id: 59894:LOC101820945
uniprot id: A0A803V107
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

59894:KCNB2
gene id: 59894:KCNB2
uniprot id: U3K1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: dendrite

59894:BICC1
gene id: 59894:BICC1
uniprot id: U3JHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BicC family.
messages: Cytoplasm

59894:ELK3
gene id: 59894:ELK3
uniprot id: U3K8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

59894:LOC101822060
gene id: 59894:LOC101822060
uniprot id: A0A803WBT7
uniprot id: U3JRV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

59894:CCKAR
gene id: 59894:CCKAR
uniprot id: U3K3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

59894:LOC101812631
gene id: 59894:LOC101812631
uniprot id: U3JVP0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

59894:MSH5
gene id: 59894:MSH5
uniprot id: U3KLN3
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

59894:KCTD20
gene id: 59894:KCTD20
uniprot id: A0A803V290
uniprot id: A0A803VY24
uniprot id: U3JKM6
names: Subcellular Location Annotation
messages: Cytoplasm

59894:LOC101808646
gene id: 59894:LOC101808646
uniprot id: U3JHQ2
names: Similarity
messages: Belongs to the avidin/streptavidin family.

59894:SPTAN1
gene id: 59894:SPTAN1
uniprot id: A0A803V212
uniprot id: A0A803W697
uniprot id: A0A803WFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

59894:SYNGR3
gene id: 59894:SYNGR3
uniprot id: U3JLE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

59894:RBM5
gene id: 59894:RBM5
uniprot id: U3K2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

59894:CASP3
gene id: 59894:CASP3
uniprot id: U3KB70
names: Similarity
messages: Belongs to the peptidase C14A family.

59894:DUS3L
gene id: 59894:DUS3L
uniprot id: U3JF48
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

59894:MON1A
gene id: 59894:MON1A
uniprot id: U3K2V5
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

59894:PRIMPOL
gene id: 59894:PRIMPOL
uniprot id: U3KB76
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

59894:AARS2
gene id: 59894:AARS2
uniprot id: A0A803VK82
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

59894:PARL
gene id: 59894:PARL
uniprot id: U3JLZ4
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101822002
gene id: 59894:LOC101822002
uniprot id: U3KHZ0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

59894:CDH18
gene id: 59894:CDH18
uniprot id: U3JYJ1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

59894:PTPRT
gene id: 59894:PTPRT
uniprot id: A0A803VLK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

59894:ANXA5
gene id: 59894:ANXA5
uniprot id: A0A803VDW6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

59894:LRRC16A
gene id: 59894:LRRC16A
uniprot id: A0A803VZT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

59894:EBAG9
gene id: 59894:EBAG9
uniprot id: A0A803VGI5
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

59894:PLXNB2
gene id: 59894:PLXNB2
uniprot id: U3K5C4
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CHAF1B
gene id: 59894:CHAF1B
uniprot id: U3K770
names: Subcellular Location Annotation
messages: Nucleus

59894:ZHX1
gene id: 59894:ZHX1
uniprot id: U3KIZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

59894:EYA3
gene id: 59894:EYA3
uniprot id: A0A803VW65
uniprot id: U3JEF6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

59894:LOC101820005
gene id: 59894:LOC101820005
uniprot id: U3K4I2
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

59894:NDUFB4
gene id: 59894:NDUFB4
uniprot id: A0A803VEW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

59894:LAMA4
gene id: 59894:LAMA4
uniprot id: A0A803VQI6
uniprot id: U3K8U2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

59894:ALDH8A1
gene id: 59894:ALDH8A1
uniprot id: A0A803V0Q7
uniprot id: U3KBL3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

59894:ADCY2
gene id: 59894:ADCY2
uniprot id: U3JXI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

59894:FZR1
gene id: 59894:FZR1
uniprot id: A0A803VCT4
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

59894:RHOT1
gene id: 59894:RHOT1
uniprot id: A0A803V2D8
uniprot id: A0A803W1W4
uniprot id: U3JHY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

59894:LOC101814429
gene id: 59894:LOC101814429
uniprot id: U3JNP7
names: Similarity
messages: Belongs to the DNase I family.

59894:AMD1
gene id: 59894:AMD1
uniprot id: U3K8A8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

59894:RPL12
gene id: 59894:RPL12
uniprot id: U3JSD6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

59894:PRDM10
gene id: 59894:PRDM10
uniprot id: A0A803VEX8
uniprot id: U3JQN2
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

59894:LOC101818404
gene id: 59894:LOC101818404
uniprot id: U3KGW5
names: Caution
names: Cofactor
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:P2RX5
gene id: 59894:P2RX5
uniprot id: U3JU46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

59894:IFNG
gene id: 59894:IFNG
uniprot id: U3K651
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer.
messages: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

59894:LOC101813071
gene id: 59894:LOC101813071
uniprot id: U3JL74
names: Function
names: Similarity
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.

59894:XYLB
gene id: 59894:XYLB
uniprot id: A0A803VMU3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

59894:TSPO
gene id: 59894:TSPO
uniprot id: A0A803VR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

59894:TMEM14A
gene id: 59894:TMEM14A
uniprot id: U3JGQ0
names: Similarity
messages: Belongs to the TMEM14 family.

59894:GJA1
gene id: 59894:GJA1
uniprot id: U3KLL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

59894:STC1
gene id: 59894:STC1
uniprot id: U3K9B2
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

59894:RC3H2
gene id: 59894:RC3H2
uniprot id: A0A803VTC0
uniprot id: U3JH35
names: Subcellular Location Annotation
messages: P-body

59894:LOC101810612
gene id: 59894:LOC101810612
uniprot id: A0A803WGH3
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

59894:CHST3
gene id: 59894:CHST3
uniprot id: A0A803V2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

59894:LOC101812090
gene id: 59894:LOC101812090
uniprot id: U3JQZ5
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:PPP4R3B
gene id: 59894:PPP4R3B
uniprot id: U3K9K3
names: Similarity
messages: Belongs to the SMEK family.

59894:LOC101819049
gene id: 59894:LOC101819049
uniprot id: A0A803VRQ9
uniprot id: U3JJM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CAND1
gene id: 59894:CAND1
uniprot id: A0A803VPA9
names: Similarity
messages: Belongs to the CAND family.

59894:PLA2G1B
gene id: 59894:PLA2G1B
uniprot id: U3JYR0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

59894:PLAGL1
gene id: 59894:PLAGL1
uniprot id: A0A803VLF4
names: Subcellular Location Annotation
messages: Nucleus

59894:ERN2
gene id: 59894:ERN2
uniprot id: U3JMG7
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101814258
gene id: 59894:LOC101814258
uniprot id: U3JLL6
names: Similarity
messages: Belongs to the FBPase class 1 family.

59894:DOK6
gene id: 59894:DOK6
uniprot id: U3JPR0
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

59894:MPV17L2
gene id: 59894:MPV17L2
uniprot id: U3JF38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

59894:LOC101822182
gene id: 59894:LOC101822182
uniprot id: U3JBQ4
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

59894:TNK2
gene id: 59894:TNK2
uniprot id: A0A803VZY6
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

59894:LOC101818745
gene id: 59894:LOC101818745
uniprot id: A0A803VGZ9
names: Similarity
messages: Belongs to the PWWP3A family.

59894:SNRPD3
gene id: 59894:SNRPD3
uniprot id: U3JXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

59894:RFC4
gene id: 59894:RFC4
uniprot id: U3K0M6
names: Similarity
messages: Belongs to the activator 1 small subunits family.

59894:LOC101816641
gene id: 59894:LOC101816641
uniprot id: A0A803W7S2
names: Similarity
messages: Belongs to the cornifelin family.

59894:ISY1
gene id: 59894:ISY1
uniprot id: U3JB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

59894:DHRS11
gene id: 59894:DHRS11
uniprot id: A0A803VZM4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

59894:BMP5
gene id: 59894:BMP5
uniprot id: U3JGJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

59894:LMNA
gene id: 59894:LMNA
uniprot id: U3JIT9
names: Similarity
messages: Belongs to the intermediate filament family.

59894:APOLD1
gene id: 59894:APOLD1
uniprot id: U3KL53
names: Similarity
messages: Belongs to the apolipoprotein L family.

59894:SEMA4G
gene id: 59894:SEMA4G
uniprot id: U3K202
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LOC101811809
gene id: 59894:LOC101811809
uniprot id: U3KL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

59894:MEOX1
gene id: 59894:MEOX1
uniprot id: U3JDJ8
names: Subcellular Location Annotation
messages: Nucleus

59894:PDGFRB
gene id: 59894:PDGFRB
uniprot id: U3JZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

59894:DOLPP1
gene id: 59894:DOLPP1
uniprot id: U3JFD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

59894:NKD1
gene id: 59894:NKD1
uniprot id: A0A803VG47
uniprot id: U3JBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

59894:CAMSAP2
gene id: 59894:CAMSAP2
uniprot id: A0A803W509
uniprot id: U3JJ58
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

59894:GPRC6A
gene id: 59894:GPRC6A
uniprot id: A0A803VYU0
uniprot id: U3K926
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

59894:CUBN
gene id: 59894:CUBN
uniprot id: U3JYD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:COL4A3BP
gene id: 59894:COL4A3BP
uniprot id: A0A803W5E9
uniprot id: U3K652
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

59894:PXN
gene id: 59894:PXN
uniprot id: A0A803V1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cell cortex
messages: cytoskeleton
messages: focal adhesion

59894:LOC101812477
gene id: 59894:LOC101812477
uniprot id: A0A803W1N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

59894:RBM17
gene id: 59894:RBM17
uniprot id: U3JGF8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

59894:ADGRL4
gene id: 59894:ADGRL4
uniprot id: U3JTU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:NPRL2
gene id: 59894:NPRL2
uniprot id: U3K2Y5
names: Similarity
messages: Belongs to the NPR2 family.

59894:STK11
gene id: 59894:STK11
uniprot id: A0A803VF14
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

59894:LIG3
gene id: 59894:LIG3
uniprot id: U3K569
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

59894:SP4
gene id: 59894:SP4
uniprot id: U3K559
names: Subcellular Location Annotation
messages: Nucleus

59894:VIPR2
gene id: 59894:VIPR2
uniprot id: U3JWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

59894:MYO1D
gene id: 59894:MYO1D
uniprot id: A0A803VG27
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

59894:GAPVD1
gene id: 59894:GAPVD1
uniprot id: A0A803VX14
uniprot id: U3JHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

59894:LPIN3
gene id: 59894:LPIN3
uniprot id: U3JSN6
names: Similarity
messages: Belongs to the lipin family.

59894:LOC101815407
gene id: 59894:LOC101815407
uniprot id: A0A803V8R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

59894:SIRT4
gene id: 59894:SIRT4
uniprot id: U3JYR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

59894:SLC30A1
gene id: 59894:SLC30A1
uniprot id: U3KDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

59894:LOC101815074
gene id: 59894:LOC101815074
uniprot id: A0A803V8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

59894:DLK2
gene id: 59894:DLK2
uniprot id: A0A803VRI4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:LIMK2
gene id: 59894:LIMK2
uniprot id: U3JYE6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

59894:ALKBH1
gene id: 59894:ALKBH1
uniprot id: U3KDN3
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

59894:LOC101819664
gene id: 59894:LOC101819664
uniprot id: U3KF10
names: Similarity
messages: Belongs to the serpin family.

59894:PANX2
gene id: 59894:PANX2
uniprot id: U3K4Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

59894:SDHAF4
gene id: 59894:SDHAF4
uniprot id: U3JWX6
names: Similarity
messages: Belongs to the SDHAF4 family.

59894:NPC1
gene id: 59894:NPC1
uniprot id: U3JUE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

59894:SKA1
gene id: 59894:SKA1
uniprot id: A0A803W4E4
names: Similarity
messages: Belongs to the SKA1 family.

59894:LOC101808986
gene id: 59894:LOC101808986
uniprot id: U3KGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

59894:AGXT
gene id: 59894:AGXT
uniprot id: U3JLI2
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

59894:CHCHD4
gene id: 59894:CHCHD4
uniprot id: A0A803W6V6
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

59894:NTN4
gene id: 59894:NTN4
uniprot id: U3K8A7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CHM
gene id: 59894:CHM
uniprot id: U3JN06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

59894:CAMK1D
gene id: 59894:CAMK1D
uniprot id: A0A803VNC0
uniprot id: A0A803VVD5
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:LBR
gene id: 59894:LBR
uniprot id: U3KB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

59894:OAZ1
gene id: 59894:OAZ1
uniprot id: U3KH92
names: Similarity
messages: Belongs to the ODC antizyme family.

59894:UGGT1
gene id: 59894:UGGT1
uniprot id: U3JLP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

59894:PTAFR
gene id: 59894:PTAFR
uniprot id: U3KIP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

59894:ABCB5
gene id: 59894:ABCB5
uniprot id: U3K561
names: Subcellular Location Annotation
messages: Membrane

59894:VAT1L
gene id: 59894:VAT1L
uniprot id: U3JBW7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

59894:NCLN
gene id: 59894:NCLN
uniprot id: A0A803W8V5
names: Function
names: Similarity
messages: Belongs to the nicastrin family.
messages: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

59894:CEP44
gene id: 59894:CEP44
uniprot id: U3KAE3
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

59894:DBNL
gene id: 59894:DBNL
uniprot id: A0A803VPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

59894:PUS7
gene id: 59894:PUS7
uniprot id: U3K6W2
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

59894:CHRNA4
gene id: 59894:CHRNA4
uniprot id: U3K764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

59894:PAN3
gene id: 59894:PAN3
uniprot id: U3K1M4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

59894:CACNG2
gene id: 59894:CACNG2
uniprot id: A0A803VED8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

59894:LOC101816390
gene id: 59894:LOC101816390
uniprot id: A0A803VJU1
uniprot id: A0A803W8X8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

59894:ARF1
gene id: 59894:ARF1
uniprot id: A0A803VL11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

59894:MAPKAPK3
gene id: 59894:MAPKAPK3
uniprot id: A0A803VNS9
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:CHRM3
gene id: 59894:CHRM3
uniprot id: U3KL06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

59894:SLC4A4
gene id: 59894:SLC4A4
uniprot id: A0A803VZU9
uniprot id: U3K110
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

59894:LOC101820998
gene id: 59894:LOC101820998
uniprot id: A0A803VMV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

59894:STAC
gene id: 59894:STAC
uniprot id: U3JJP5
names: Subcellular Location Annotation
messages: sarcolemma

59894:F7
gene id: 59894:F7
uniprot id: U3JP47
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:IGF1
gene id: 59894:IGF1
uniprot id: U3K384
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

59894:SLC16A5
gene id: 59894:SLC16A5
uniprot id: U3JES7
names: Subcellular Location Annotation
messages: Membrane

59894:FURIN
gene id: 59894:FURIN
uniprot id: U3K9L3
names: Similarity
messages: Belongs to the peptidase S8 family.

59894:INPP5B
gene id: 59894:INPP5B
uniprot id: U3JE26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

59894:RAB4A
gene id: 59894:RAB4A
uniprot id: U3JL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

59894:LOC101810182
gene id: 59894:LOC101810182
uniprot id: U3KGI2
names: Similarity
messages: Belongs to the ARTD/PARP family.

59894:PSMC3IP
gene id: 59894:PSMC3IP
uniprot id: A0A803WGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

59894:PTGER4
gene id: 59894:PTGER4
uniprot id: U3JH44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

59894:NUP35
gene id: 59894:NUP35
uniprot id: U3KFE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

59894:MOGAT1
gene id: 59894:MOGAT1
uniprot id: A0A803VWV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CLDN12
gene id: 59894:CLDN12
uniprot id: U3KJ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

59894:C9
gene id: 59894:C9
uniprot id: A0A803W223
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

59894:UBR2
gene id: 59894:UBR2
uniprot id: U3KDP2
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

59894:LOC101821176
gene id: 59894:LOC101821176
uniprot id: U3JM30
names: Subcellular Location Annotation
messages: Membrane

59894:ORC6
gene id: 59894:ORC6
uniprot id: A0A803VMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

59894:SEPT11
gene id: 59894:SEPT11
uniprot id: U3K1F7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

59894:LOC101815188
gene id: 59894:LOC101815188
uniprot id: A0A803VSY4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

59894:LOC101810556
gene id: 59894:LOC101810556
uniprot id: U3K475
names: Similarity
messages: Belongs to the amidase family.

59894:CAMK2G
gene id: 59894:CAMK2G
uniprot id: A0A803V6D0
uniprot id: A0A803VGD2
uniprot id: A0A803VLU5
uniprot id: A0A803VVM7
uniprot id: A0A803WCD9
uniprot id: U3JX42
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

59894:CPT1A
gene id: 59894:CPT1A
uniprot id: U3KDP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

59894:BORCS5
gene id: 59894:BORCS5
uniprot id: U3JIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

59894:KDM4A
gene id: 59894:KDM4A
uniprot id: U3JS96
names: Subcellular Location Annotation
messages: Nucleus

59894:PEBP1
gene id: 59894:PEBP1
uniprot id: A0A803V8D0
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

59894:LOC101811789
gene id: 59894:LOC101811789
uniprot id: A0A803VY64
names: Similarity
messages: Belongs to the globin family.

59894:ANTXRL
gene id: 59894:ANTXRL
uniprot id: A0A803W1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

59894:KCTD10
gene id: 59894:KCTD10
uniprot id: A0A803VCP3
names: Similarity
messages: Belongs to the BACURD family.

59894:DOCK4
gene id: 59894:DOCK4
uniprot id: A0A803VI16
names: Similarity
messages: Belongs to the DOCK family.

59894:ZC3H15
gene id: 59894:ZC3H15
uniprot id: A0A803V2K2
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

59894:PRKCQ
gene id: 59894:PRKCQ
uniprot id: U3JGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

59894:DYNLL1
gene id: 59894:DYNLL1
uniprot id: A0A803V3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

59894:TMC7
gene id: 59894:TMC7
uniprot id: U3KI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

59894:CAPN15
gene id: 59894:CAPN15
uniprot id: A0A803W1W6
names: Similarity
messages: Belongs to the peptidase C2 family.

59894:ATG13
gene id: 59894:ATG13
uniprot id: A0A803V5B5
uniprot id: U3JUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

59894:FUBP1
gene id: 59894:FUBP1
uniprot id: A0A803VCV6
uniprot id: A0A803WCG4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:TRPM6
gene id: 59894:TRPM6
uniprot id: A0A803VYG9
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

59894:MMP23B
gene id: 59894:MMP23B
uniprot id: U3K432
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:PHKA2
gene id: 59894:PHKA2
uniprot id: A0A803V3Q9
uniprot id: A0A803W5S9
uniprot id: U3JNW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

59894:CRK
gene id: 59894:CRK
uniprot id: A0A803V939
names: Similarity
messages: Belongs to the CRK family.

59894:HSPB8
gene id: 59894:HSPB8
uniprot id: U3JZ23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Displays temperature-dependent chaperone activity.

59894:APLP2
gene id: 59894:APLP2
uniprot id: A0A803V1L5
uniprot id: A0A803VJR9
uniprot id: U3JQN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:LOC101805774
gene id: 59894:LOC101805774
uniprot id: U3JGF7
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

59894:SGTB
gene id: 59894:SGTB
uniprot id: A0A803VVS2
names: Similarity
messages: Belongs to the SGT family.

59894:EMC6
gene id: 59894:EMC6
uniprot id: U3KL55
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

59894:CDS1
gene id: 59894:CDS1
uniprot id: U3JS21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

59894:LOC101808879
gene id: 59894:LOC101808879
uniprot id: U3JD40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

59894:CHST8
gene id: 59894:CHST8
uniprot id: U3JZB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:ACLY
gene id: 59894:ACLY
uniprot id: A0A803VV09
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

59894:MRPL13
gene id: 59894:MRPL13
uniprot id: A0A803WFM3
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

59894:SSR2
gene id: 59894:SSR2
uniprot id: A0A803V9C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

59894:TTC38
gene id: 59894:TTC38
uniprot id: U3JJL8
names: Similarity
messages: Belongs to the TTC38 family.

59894:UGT8
gene id: 59894:UGT8
uniprot id: U3JE99
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

59894:ZHX3
gene id: 59894:ZHX3
uniprot id: U3JSP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

59894:EPC2
gene id: 59894:EPC2
uniprot id: A0A803WDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

59894:LOC101814982
gene id: 59894:LOC101814982
uniprot id: U3JZM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

59894:STK3
gene id: 59894:STK3
uniprot id: A0A803VAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

59894:PSMB2
gene id: 59894:PSMB2
uniprot id: A0A803W592
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

59894:LOC101820076
gene id: 59894:LOC101820076
uniprot id: U3JSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

59894:FCF1
gene id: 59894:FCF1
uniprot id: U3JUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

59894:FAT2
gene id: 59894:FAT2
uniprot id: U3K0L5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:KIAA2022
gene id: 59894:KIAA2022
uniprot id: A0A803VRN3
names: Subcellular Location Annotation
messages: Nucleus

59894:LOC101815274
gene id: 59894:LOC101815274
uniprot id: U3KF66
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

59894:SLC6A4
gene id: 59894:SLC6A4
uniprot id: U3JUM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Synapse
messages: focal adhesion
messages: neuron projection

59894:PIAS2
gene id: 59894:PIAS2
uniprot id: U3K2R0
names: Similarity
messages: Belongs to the PIAS family.

59894:SF3B5
gene id: 59894:SF3B5
uniprot id: U3KKS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

59894:PPFIBP1
gene id: 59894:PPFIBP1
uniprot id: A0A803V6H5
uniprot id: A0A803VXI8
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

59894:CRYL1
gene id: 59894:CRYL1
uniprot id: U3K268
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

59894:SLC35E3
gene id: 59894:SLC35E3
uniprot id: A0A803VZU5
names: Subcellular Location Annotation
messages: Membrane

59894:NPBWR1
gene id: 59894:NPBWR1
uniprot id: U3KK50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

59894:LOC101810101
gene id: 59894:LOC101810101
uniprot id: A0A803V395
uniprot id: U3KBK9
names: Similarity
messages: Belongs to the protein kinase superfamily.

59894:SH3BGRL
gene id: 59894:SH3BGRL
uniprot id: A0A803V1B7
names: Similarity
messages: Belongs to the SH3BGR family.

59894:UXS1
gene id: 59894:UXS1
uniprot id: U3JLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

59894:POLR3K
gene id: 59894:POLR3K
uniprot id: U3JN74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

59894:PRPH2
gene id: 59894:PRPH2
uniprot id: U3KDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

59894:TEKT1
gene id: 59894:TEKT1
uniprot id: U3JPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

59894:FAM129A
gene id: 59894:FAM129A
uniprot id: A0A803VTJ6
names: Similarity
messages: Belongs to the Niban family.

59894:LOC101810446
gene id: 59894:LOC101810446
uniprot id: A0A803V5L4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CAPZA2
gene id: 59894:CAPZA2
uniprot id: A0A803W6J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

59894:HCK
gene id: 59894:HCK
uniprot id: U3JSC9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

59894:SMARCAL1
gene id: 59894:SMARCAL1
uniprot id: A0A803VJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

59894:NDST4
gene id: 59894:NDST4
uniprot id: U3JEC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

59894:HTR2B
gene id: 59894:HTR2B
uniprot id: U3JYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

59894:LOC101819832
gene id: 59894:LOC101819832
uniprot id: U3KHP6
names: Similarity
messages: Belongs to the cytochrome P450 family.

59894:COX2
gene id: 59894:COX2
uniprot id: S0AT20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

59894:PLPP2
gene id: 59894:PLPP2
uniprot id: U3KHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

59894:PSMD9
gene id: 59894:PSMD9
uniprot id: A0A803VK46
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

59894:PCSK7
gene id: 59894:PCSK7
uniprot id: U3JTB5
names: Similarity
messages: Belongs to the peptidase S8 family.

59894:SMARCAD1
gene id: 59894:SMARCAD1
uniprot id: A0A803VDR8
names: Subcellular Location Annotation
messages: Chromosome

59894:TPX2
gene id: 59894:TPX2
uniprot id: U3JSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

59894:ATP12A
gene id: 59894:ATP12A
uniprot id: U3JT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

59894:EMP1
gene id: 59894:EMP1
uniprot id: U3KAB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

59894:ILKAP
gene id: 59894:ILKAP
uniprot id: U3JLJ1
names: Similarity
messages: Belongs to the PP2C family.

59894:LOC101815087
gene id: 59894:LOC101815087
uniprot id: U3JY85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

59894:LOC101812234
gene id: 59894:LOC101812234
uniprot id: A0A803W4T2
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

59894:PEX7
gene id: 59894:PEX7
uniprot id: U3KEJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

59894:MRRF
gene id: 59894:MRRF
uniprot id: A0A803VHA9
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

59894:TRAF3
gene id: 59894:TRAF3
uniprot id: A0A803VUV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

59894:IPO5
gene id: 59894:IPO5
uniprot id: U3JP88
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

59894:LOC101818299
gene id: 59894:LOC101818299
uniprot id: U3KIN8
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

59894:PAX2
gene id: 59894:PAX2
uniprot id: U3JXX5
names: Subcellular Location Annotation
messages: Nucleus

59894:NDUFA11
gene id: 59894:NDUFA11
uniprot id: U3KBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA11 subunit family.
messages: Mitochondrion inner membrane

59894:GGT1
gene id: 59894:GGT1
uniprot id: A0A803VII8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:ATP6V0D1
gene id: 59894:ATP6V0D1
uniprot id: A0A803VWD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

59894:PPP2R5C
gene id: 59894:PPP2R5C
uniprot id: U3JJ70
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

59894:AIG1
gene id: 59894:AIG1
uniprot id: U3KE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

59894:NKX2-1
gene id: 59894:NKX2-1
uniprot id: U3JUF7
names: Subcellular Location Annotation
messages: Nucleus

59894:PAX9
gene id: 59894:PAX9
uniprot id: U3JUG2
names: Subcellular Location Annotation
messages: Nucleus

59894:BCL9L
gene id: 59894:BCL9L
uniprot id: U3K5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

59894:GCNT7
gene id: 59894:GCNT7
uniprot id: A0A803WDA7
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

59894:MTMR10
gene id: 59894:MTMR10
uniprot id: U3KDH2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

59894:MC5R
gene id: 59894:MC5R
uniprot id: U3KIF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

59894:SRP9
gene id: 59894:SRP9
uniprot id: A0A803V9W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

59894:CRBN
gene id: 59894:CRBN
uniprot id: U3KGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

59894:BMP10
gene id: 59894:BMP10
uniprot id: A0A803WAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

59894:TUB
gene id: 59894:TUB
uniprot id: A0A803V2S9
uniprot id: A0A803VK12
uniprot id: U3JDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

59894:DESI2
gene id: 59894:DESI2
uniprot id: U3KAG1
names: Similarity
messages: Belongs to the DeSI family.

59894:NME3
gene id: 59894:NME3
uniprot id: A0A803VKJ7
names: Similarity
messages: Belongs to the NDK family.

59894:MARCO
gene id: 59894:MARCO
uniprot id: U3KGT2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:EHHADH
gene id: 59894:EHHADH
uniprot id: U3KG80
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

59894:MAGOH
gene id: 59894:MAGOH
uniprot id: U3JT84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

59894:ZNF326
gene id: 59894:ZNF326
uniprot id: U3JG34
names: Similarity
messages: Belongs to the AKAP95 family.

59894:PDE1A
gene id: 59894:PDE1A
uniprot id: A0A803VTQ9
uniprot id: A0A803VZ62
uniprot id: U3JLV3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:ATP6V1A
gene id: 59894:ATP6V1A
uniprot id: U3JRC0
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

59894:F3
gene id: 59894:F3
uniprot id: U3JI36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

59894:YWHAQ
gene id: 59894:YWHAQ
uniprot id: A0A803VRU4
names: Similarity
messages: Belongs to the 14-3-3 family.

59894:SCG2
gene id: 59894:SCG2
uniprot id: U3JW98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

59894:HS2ST1
gene id: 59894:HS2ST1
uniprot id: A0A803VGD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

59894:KCNG1
gene id: 59894:KCNG1
uniprot id: U3KF05
names: Subcellular Location Annotation
messages: Membrane

59894:GPAM
gene id: 59894:GPAM
uniprot id: U3JHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

59894:FAM20B
gene id: 59894:FAM20B
uniprot id: U3K0J0
names: Similarity
messages: Belongs to the FAM20 family.

59894:TENM1
gene id: 59894:TENM1
uniprot id: A0A803VIC3
uniprot id: U3JFL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:LUC7L
gene id: 59894:LUC7L
uniprot id: U3JNG8
names: Similarity
messages: Belongs to the Luc7 family.

59894:SEC13
gene id: 59894:SEC13
uniprot id: A0A803VVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

59894:CPLX3
gene id: 59894:CPLX3
uniprot id: U3K8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

59894:DLK1
gene id: 59894:DLK1
uniprot id: U3JJ67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:GLB1L
gene id: 59894:GLB1L
uniprot id: U3JNR1
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

59894:BNIP1
gene id: 59894:BNIP1
uniprot id: U3K2D9
names: Subcellular Location Annotation
messages: Membrane

59894:PITPNM3
gene id: 59894:PITPNM3
uniprot id: U3JPZ7
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

59894:TRPC4
gene id: 59894:TRPC4
uniprot id: U3K0H3
names: Subcellular Location Annotation
messages: Membrane

59894:LOC101819738
gene id: 59894:LOC101819738
uniprot id: U3KK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

59894:PDE8A
gene id: 59894:PDE8A
uniprot id: A0A803VBC7
uniprot id: A0A803VP06
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

59894:LMOD1
gene id: 59894:LMOD1
uniprot id: U3JI89
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

59894:CCDC39
gene id: 59894:CCDC39
uniprot id: U3K0V7
names: Similarity
messages: Belongs to the CCDC39 family.

59894:SNTB2
gene id: 59894:SNTB2
uniprot id: U3JJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

59894:TMEM65
gene id: 59894:TMEM65
uniprot id: A0A803V031
names: Subcellular Location Annotation
messages: Membrane

59894:ACVR2B
gene id: 59894:ACVR2B
uniprot id: U3JWE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

59894:POLR2B
gene id: 59894:POLR2B
uniprot id: U3JTT7
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

59894:SNTG1
gene id: 59894:SNTG1
uniprot id: U3JT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

59894:EFEMP1
gene id: 59894:EFEMP1
uniprot id: U3K9I7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:MAST3
gene id: 59894:MAST3
uniprot id: A0A803VG65
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

59894:CCNI
gene id: 59894:CCNI
uniprot id: U3K1G0
names: Similarity
messages: Belongs to the cyclin family.

59894:ACO2
gene id: 59894:ACO2
uniprot id: A0A803VP94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

59894:PRKAB2
gene id: 59894:PRKAB2
uniprot id: U3JME5
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

59894:LAMC1
gene id: 59894:LAMC1
uniprot id: U3JK20
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

59894:ACTR1A
gene id: 59894:ACTR1A
uniprot id: U3K221
names: Similarity
messages: Belongs to the actin family.

59894:RARS2
gene id: 59894:RARS2
uniprot id: U3JJV3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

59894:NKX6-2
gene id: 59894:NKX6-2
uniprot id: U3JF17
names: Subcellular Location Annotation
messages: Nucleus

59894:YIPF1
gene id: 59894:YIPF1
uniprot id: U3KBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

59894:NPNT
gene id: 59894:NPNT
uniprot id: A0A803V555
uniprot id: U3KD20
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:CERS4
gene id: 59894:CERS4
uniprot id: U3KBM2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

59894:LHFPL3
gene id: 59894:LHFPL3
uniprot id: A0A803V2I4
names: Subcellular Location Annotation
messages: Membrane

59894:PPM1B
gene id: 59894:PPM1B
uniprot id: A0A803VK77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

59894:GTPBP10
gene id: 59894:GTPBP10
uniprot id: U3JZ35
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

59894:ALOX5
gene id: 59894:ALOX5
uniprot id: U3JY58
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

59894:NADK
gene id: 59894:NADK
uniprot id: A0A803V6T9
names: Similarity
messages: Belongs to the NAD kinase family.

59894:ALDOC
gene id: 59894:ALDOC
uniprot id: U3JVB0
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

59894:PCNX4
gene id: 59894:PCNX4
uniprot id: U3JLF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

59894:FLT4
gene id: 59894:FLT4
uniprot id: U3JZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

59894:PPP1R12A
gene id: 59894:PPP1R12A
uniprot id: A0A803W6A6
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

59894:LOC101819516
gene id: 59894:LOC101819516
uniprot id: A0A803VCK4
names: Similarity
messages: Belongs to the perilipin family.

59894:GPR83
gene id: 59894:GPR83
uniprot id: U3JC17
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

59894:CMTM8
gene id: 59894:CMTM8
uniprot id: U3K3D2
names: Subcellular Location Annotation
messages: Membrane

59894:PPFIA2
gene id: 59894:PPFIA2
uniprot id: U3K7H1
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

59894:WNT2
gene id: 59894:WNT2
uniprot id: A0A803VJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

59894:MET
gene id: 59894:MET
uniprot id: A0A803VZ61
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

59894:CPPED1
gene id: 59894:CPPED1
uniprot id: A0A803V3U2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.

59894:SLC7A3
gene id: 59894:SLC7A3
uniprot id: U3KBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

59894:ARAP3
gene id: 59894:ARAP3
uniprot id: A0A803VHY5
uniprot id: U3JJV7
names: Subcellular Location Annotation
messages: Cytoplasm

59894:GSG1L2
gene id: 59894:GSG1L2
uniprot id: U3JD63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

59894:CPNE2
gene id: 59894:CPNE2
uniprot id: U3JX01
names: Similarity
messages: Belongs to the copine family.

59894:ADCY7
gene id: 59894:ADCY7
uniprot id: U3JBD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

59894:PPP3R1
gene id: 59894:PPP3R1
uniprot id: U3KGU1
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

59894:UBE4B
gene id: 59894:UBE4B
uniprot id: U3JXQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

59894:PDE4D
gene id: 59894:PDE4D
uniprot id: A0A803V6H3
uniprot id: A0A803WA13
uniprot id: A0A803WCW9
uniprot id: U3K8Z6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.