598659:NAMH RS01210
gene id: 598659:NAMH_RS01210
uniprot id: B9L7R0
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08195
gene id: 598659:NAMH_RS08195
uniprot id: B9L6Q8
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS05130
gene id: 598659:NAMH_RS05130
uniprot id: B9L9Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterioferritin family.
messages: Cytoplasm
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

598659:NAMH RS00635
gene id: 598659:NAMH_RS00635
uniprot id: B9L7F6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

598659:NAMH RS00190
gene id: 598659:NAMH_RS00190
uniprot id: B9L772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

598659:NAMH RS05665
gene id: 598659:NAMH_RS05665
uniprot id: B9LA86
names: Similarity
messages: Belongs to the GSP E family.

598659:NAMH RS07425
gene id: 598659:NAMH_RS07425
uniprot id: B9L6B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

598659:NAMH RS06945
gene id: 598659:NAMH_RS06945
uniprot id: B9L616
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

598659:NAMH RS00260
gene id: 598659:NAMH_RS00260
uniprot id: B9L785
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

598659:NAMH RS08300
gene id: 598659:NAMH_RS08300
uniprot id: B9L6T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

598659:NAMH RS03915
gene id: 598659:NAMH_RS03915
uniprot id: B9L985
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

598659:NAMH RS07820
gene id: 598659:NAMH_RS07820
uniprot id: B9L6I8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

598659:NAMH RS07590
gene id: 598659:NAMH_RS07590
uniprot id: B9L6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

598659:NAMH RS02350
gene id: 598659:NAMH_RS02350
uniprot id: B9L8D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

598659:NAMH RS04110
gene id: 598659:NAMH_RS04110
uniprot id: B9L9C5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

598659:NAMH RS01775
gene id: 598659:NAMH_RS01775
uniprot id: B9L823
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

598659:NAMH RS08570
gene id: 598659:NAMH_RS08570
uniprot id: B9L6X8
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS04790
gene id: 598659:NAMH_RS04790
uniprot id: B9L9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Membrane

598659:NAMH RS02380
gene id: 598659:NAMH_RS02380
uniprot id: B9L8D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

598659:NAMH RS08215
gene id: 598659:NAMH_RS08215
uniprot id: B9L6R2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

598659:NAMH RS00340
gene id: 598659:NAMH_RS00340
uniprot id: B9L7A1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS04780
gene id: 598659:NAMH_RS04780
uniprot id: B9L9R1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS02105
gene id: 598659:NAMH_RS02105
uniprot id: B9L889
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

598659:NAMH RS08330
gene id: 598659:NAMH_RS08330
uniprot id: B9L6T6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

598659:NAMH RS06455
gene id: 598659:NAMH_RS06455
uniprot id: B9L5R5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

598659:NAMH RS02860
gene id: 598659:NAMH_RS02860
uniprot id: B9L8N3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

598659:NAMH RS01350
gene id: 598659:NAMH_RS01350
uniprot id: B9L7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

598659:NAMH RS02865
gene id: 598659:NAMH_RS02865
uniprot id: B9L8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

598659:NAMH RS02235
gene id: 598659:NAMH_RS02235
uniprot id: B9L8B1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

598659:NAMH RS05085
gene id: 598659:NAMH_RS05085
uniprot id: B9L9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

598659:NAMH RS07360
gene id: 598659:NAMH_RS07360
uniprot id: B9L697
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

598659:NAMH RS01715
gene id: 598659:NAMH_RS01715
uniprot id: B9L811
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

598659:NAMH RS02070
gene id: 598659:NAMH_RS02070
uniprot id: B9L882
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

598659:NAMH RS00280
gene id: 598659:NAMH_RS00280
uniprot id: B9L789
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

598659:NAMH RS00130
gene id: 598659:NAMH_RS00130
uniprot id: B9L760
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

598659:NAMH RS04015
gene id: 598659:NAMH_RS04015
uniprot id: B9L9A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

598659:NAMH RS05760
gene id: 598659:NAMH_RS05760
uniprot id: B9LAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

598659:NAMH RS05680
gene id: 598659:NAMH_RS05680
uniprot id: B9LA89
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

598659:NAMH RS00535
gene id: 598659:NAMH_RS00535
uniprot id: B9L7D6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS04900
gene id: 598659:NAMH_RS04900
uniprot id: B9L9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

598659:NAMH RS00980
gene id: 598659:NAMH_RS00980
uniprot id: B9L7L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

598659:NAMH RS06610
gene id: 598659:NAMH_RS06610
uniprot id: B9L5U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS02240
gene id: 598659:NAMH_RS02240
uniprot id: B9L8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

598659:NAMH RS07550
gene id: 598659:NAMH_RS07550
uniprot id: B9L6D5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

598659:NAMH RS08050
gene id: 598659:NAMH_RS08050
uniprot id: B9L6M9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

598659:NAMH RS05340
gene id: 598659:NAMH_RS05340
uniprot id: B9LA24
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

598659:NAMH RS03860
gene id: 598659:NAMH_RS03860
uniprot id: B9L974
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS01455
gene id: 598659:NAMH_RS01455
uniprot id: B9L7V9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

598659:NAMH RS02325
gene id: 598659:NAMH_RS02325
uniprot id: B9L8C8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

598659:NAMH RS02870
gene id: 598659:NAMH_RS02870
uniprot id: B9L8N5
names: Similarity
messages: Belongs to the peptidase A31 family.

598659:NAMH RS08090
gene id: 598659:NAMH_RS08090
uniprot id: B9L6N7
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS02440
gene id: 598659:NAMH_RS02440
uniprot id: B9L8F1
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS04610
gene id: 598659:NAMH_RS04610
uniprot id: B9L9M7
names: Similarity
messages: Belongs to the UPF0045 family.

598659:NAMH RS05020
gene id: 598659:NAMH_RS05020
uniprot id: B9L9W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

598659:NAMH RS08425
gene id: 598659:NAMH_RS08425
uniprot id: B9L6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

598659:NAMH RS00010
gene id: 598659:NAMH_RS00010
uniprot id: B9L736
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

598659:NAMH RS03725
gene id: 598659:NAMH_RS03725
uniprot id: B9L946
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS07680
gene id: 598659:NAMH_RS07680
uniprot id: B9L6G1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

598659:NAMH RS02255
gene id: 598659:NAMH_RS02255
uniprot id: B9L8B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

598659:NAMH RS03130
gene id: 598659:NAMH_RS03130
uniprot id: B9L8T8
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS05425
gene id: 598659:NAMH_RS05425
uniprot id: B9LA39
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

598659:NAMH RS03515
gene id: 598659:NAMH_RS03515
uniprot id: B9L912
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

598659:NAMH RS06150
gene id: 598659:NAMH_RS06150
uniprot id: B9L5K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

598659:NAMH RS01525
gene id: 598659:NAMH_RS01525
uniprot id: B9L7X3
names: Similarity
messages: Belongs to the PstS family.

598659:NAMH RS04175
gene id: 598659:NAMH_RS04175
uniprot id: B9L9D9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS00235
gene id: 598659:NAMH_RS00235
uniprot id: B9L781
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

598659:NAMH RS07080
gene id: 598659:NAMH_RS07080
uniprot id: B9L643
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

598659:NAMH RS04105
gene id: 598659:NAMH_RS04105
uniprot id: B9L9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

598659:NAMH RS01700
gene id: 598659:NAMH_RS01700
uniprot id: B9L808
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS04665
gene id: 598659:NAMH_RS04665
uniprot id: B9L9N8
names: Similarity
messages: Belongs to the acylphosphatase family.

598659:NAMH RS03760
gene id: 598659:NAMH_RS03760
uniprot id: B9L953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

598659:NAMH RS02700
gene id: 598659:NAMH_RS02700
uniprot id: B9L8K1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

598659:NAMH RS06705
gene id: 598659:NAMH_RS06705
uniprot id: B9L5W8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

598659:NAMH RS04410
gene id: 598659:NAMH_RS04410
uniprot id: B9L9I7
names: Similarity
messages: Belongs to the XseB family.

598659:NAMH RS08270
gene id: 598659:NAMH_RS08270
uniprot id: B9L6S4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

598659:NAMH RS00710
gene id: 598659:NAMH_RS00710
uniprot id: B9L7H1
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

598659:NAMH RS08105
gene id: 598659:NAMH_RS08105
uniprot id: B9L6P0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

598659:NAMH RS07095
gene id: 598659:NAMH_RS07095
uniprot id: B9L646
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

598659:NAMH RS05960
gene id: 598659:NAMH_RS05960
uniprot id: B9LAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

598659:NAMH RS07805
gene id: 598659:NAMH_RS07805
uniprot id: B9L6I5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

598659:NAMH RS07480
gene id: 598659:NAMH_RS07480
uniprot id: B9L6C3
names: Similarity
messages: Belongs to the thioredoxin family.

598659:NAMH RS04025
gene id: 598659:NAMH_RS04025
uniprot id: B9L9A8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

598659:NAMH RS03620
gene id: 598659:NAMH_RS03620
uniprot id: B9L928
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

598659:NAMH RS04310
gene id: 598659:NAMH_RS04310
uniprot id: B9L9G7
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

598659:NAMH RS01680
gene id: 598659:NAMH_RS01680
uniprot id: B9L804
names: Similarity
messages: Belongs to the RNase T2 family.

598659:NAMH RS04355
gene id: 598659:NAMH_RS04355
uniprot id: B9L9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

598659:NAMH RS08790
gene id: 598659:NAMH_RS08790
uniprot id: B9L716
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

598659:NAMH RS03120
gene id: 598659:NAMH_RS03120
uniprot id: B9L8T6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

598659:NAMH RS07675
gene id: 598659:NAMH_RS07675
uniprot id: B9L6G0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

598659:NAMH RS08305
gene id: 598659:NAMH_RS08305
uniprot id: B9L6T1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

598659:NAMH RS05910
gene id: 598659:NAMH_RS05910
uniprot id: B9LAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

598659:NAMH RS08440
gene id: 598659:NAMH_RS08440
uniprot id: B9L6V7
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS01780
gene id: 598659:NAMH_RS01780
uniprot id: B9L824
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

598659:NAMH RS00860
gene id: 598659:NAMH_RS00860
uniprot id: B9L7J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

598659:NAMH RS00195
gene id: 598659:NAMH_RS00195
uniprot id: B9L773
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

598659:NAMH RS01360
gene id: 598659:NAMH_RS01360
uniprot id: B9L7U0
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS04760
gene id: 598659:NAMH_RS04760
uniprot id: B9L9Q8
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00630
gene id: 598659:NAMH_RS00630
uniprot id: B9L7F5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

598659:NAMH RS01530
gene id: 598659:NAMH_RS01530
uniprot id: B9L7X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

598659:NAMH RS07655
gene id: 598659:NAMH_RS07655
uniprot id: B9L6F6
names: Similarity
messages: Belongs to the DEAD box helicase family.

598659:NAMH RS05545
gene id: 598659:NAMH_RS05545
uniprot id: B9LA63
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

598659:NAMH RS07785
gene id: 598659:NAMH_RS07785
uniprot id: B9L6I1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

598659:NAMH RS04895
gene id: 598659:NAMH_RS04895
uniprot id: B9L9T4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

598659:NAMH RS06335
gene id: 598659:NAMH_RS06335
uniprot id: B9L5N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

598659:NAMH RS05735
gene id: 598659:NAMH_RS05735
uniprot id: B9LAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS00580
gene id: 598659:NAMH_RS00580
uniprot id: B9L7E5
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00100
gene id: 598659:NAMH_RS00100
uniprot id: B9L754
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

598659:NAMH RS03770
gene id: 598659:NAMH_RS03770
uniprot id: B9L955
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

598659:NAMH RS04440
gene id: 598659:NAMH_RS04440
uniprot id: B9L9J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS00070
gene id: 598659:NAMH_RS00070
uniprot id: B9L748
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS03135
gene id: 598659:NAMH_RS03135
uniprot id: B9L8T9
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS03235
gene id: 598659:NAMH_RS03235
uniprot id: B9L8V5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

598659:NAMH RS05460
gene id: 598659:NAMH_RS05460
uniprot id: B9LA46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

598659:NAMH RS05360
gene id: 598659:NAMH_RS05360
uniprot id: B9LA28
names: Similarity
messages: Belongs to the TlyA family.

598659:NAMH RS06735
gene id: 598659:NAMH_RS06735
uniprot id: B9L5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

598659:NAMH RS05755
gene id: 598659:NAMH_RS05755
uniprot id: B9LAA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

598659:NAMH RS04775
gene id: 598659:NAMH_RS04775
uniprot id: B9L9R0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

598659:NAMH RS03445
gene id: 598659:NAMH_RS03445
uniprot id: B9L8Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

598659:NAMH RS08660
gene id: 598659:NAMH_RS08660
uniprot id: B9L6Z1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

598659:NAMH RS05580
gene id: 598659:NAMH_RS05580
uniprot id: B9LA69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

598659:NAMH RS00310
gene id: 598659:NAMH_RS00310
uniprot id: B9L795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

598659:NAMH RS04525
gene id: 598659:NAMH_RS04525
uniprot id: B9L9L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS01980
gene id: 598659:NAMH_RS01980
uniprot id: B9L865
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

598659:NAMH RS03270
gene id: 598659:NAMH_RS03270
uniprot id: B9L8W2
names: Similarity
messages: Belongs to the YggT family.

598659:NAMH RS07830
gene id: 598659:NAMH_RS07830
uniprot id: B9L6J0
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

598659:NAMH RS04650
gene id: 598659:NAMH_RS04650
uniprot id: B9L9N5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS03040
gene id: 598659:NAMH_RS03040
uniprot id: B9L8S0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

598659:NAMH RS06090
gene id: 598659:NAMH_RS06090
uniprot id: B9L5J0
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

598659:NAMH RS02455
gene id: 598659:NAMH_RS02455
uniprot id: B9L8F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

598659:NAMH RS03450
gene id: 598659:NAMH_RS03450
uniprot id: B9L8Z9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

598659:NAMH RS02605
gene id: 598659:NAMH_RS02605
uniprot id: B9L8I4
names: Similarity
messages: Belongs to the YoeB family.

598659:NAMH RS03840
gene id: 598659:NAMH_RS03840
uniprot id: B9L970
names: Subcellular Location Annotation
messages: Cytoplasm

598659:NAMH RS08800
gene id: 598659:NAMH_RS08800
uniprot id: B9L718
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

598659:NAMH RS03740
gene id: 598659:NAMH_RS03740
uniprot id: B9L949
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS04960
gene id: 598659:NAMH_RS04960
uniprot id: B9L9U8
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS01165
gene id: 598659:NAMH_RS01165
uniprot id: B9L7Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

598659:NAMH RS03380
gene id: 598659:NAMH_RS03380
uniprot id: B9L8Y5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

598659:NAMH RS08415
gene id: 598659:NAMH_RS08415
uniprot id: B9L6V2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

598659:NAMH RS07150
gene id: 598659:NAMH_RS07150
uniprot id: B9L657
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

598659:NAMH RS07975
gene id: 598659:NAMH_RS07975
uniprot id: B9L6L4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

598659:NAMH RS02285
gene id: 598659:NAMH_RS02285
uniprot id: B9L8C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

598659:NAMH RS01910
gene id: 598659:NAMH_RS01910
uniprot id: B9L851
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

598659:NAMH RS04825
gene id: 598659:NAMH_RS04825
uniprot id: B9L9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

598659:NAMH RS08705
gene id: 598659:NAMH_RS08705
uniprot id: B9L6Z8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

598659:NAMH RS05490
gene id: 598659:NAMH_RS05490
uniprot id: B9LA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

598659:NAMH RS05430
gene id: 598659:NAMH_RS05430
uniprot id: B9LA40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

598659:NAMH RS07580
gene id: 598659:NAMH_RS07580
uniprot id: B9L6E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

598659:NAMH RS04540
gene id: 598659:NAMH_RS04540
uniprot id: B9L9L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

598659:NAMH RS02560
gene id: 598659:NAMH_RS02560
uniprot id: B9L8H5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

598659:NAMH RS01665
gene id: 598659:NAMH_RS01665
uniprot id: B9L801
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS01135
gene id: 598659:NAMH_RS01135
uniprot id: B9L7P5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

598659:NAMH RS00690
gene id: 598659:NAMH_RS00690
uniprot id: B9L7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

598659:NAMH RS02420
gene id: 598659:NAMH_RS02420
uniprot id: B9L8E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

598659:NAMH RS05125
gene id: 598659:NAMH_RS05125
uniprot id: B9L9Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS03925
gene id: 598659:NAMH_RS03925
uniprot id: B9L987
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

598659:NAMH RS03460
gene id: 598659:NAMH_RS03460
uniprot id: B9L901
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

598659:NAMH RS02815
gene id: 598659:NAMH_RS02815
uniprot id: B9L8M4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

598659:NAMH RS08530
gene id: 598659:NAMH_RS08530
uniprot id: B9L6X5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

598659:NAMH RS06130
gene id: 598659:NAMH_RS06130
uniprot id: B9L5J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS00880
gene id: 598659:NAMH_RS00880
uniprot id: B9L7J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

598659:NAMH RS03775
gene id: 598659:NAMH_RS03775
uniprot id: B9L956
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

598659:NAMH RS04815
gene id: 598659:NAMH_RS04815
uniprot id: B9L9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

598659:NAMH RS02620
gene id: 598659:NAMH_RS02620
uniprot id: B9L8I7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

598659:NAMH RS04165
gene id: 598659:NAMH_RS04165
uniprot id: B9L9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

598659:NAMH RS02595
gene id: 598659:NAMH_RS02595
uniprot id: B9L8I2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

598659:NAMH RS03780
gene id: 598659:NAMH_RS03780
uniprot id: B9L957
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

598659:NAMH RS04350
gene id: 598659:NAMH_RS04350
uniprot id: B9L9H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

598659:NAMH RS01260
gene id: 598659:NAMH_RS01260
uniprot id: B9L7S0
names: Similarity
messages: Belongs to the RecJ family.

598659:NAMH RS04215
gene id: 598659:NAMH_RS04215
uniprot id: B9L9E7
names: Similarity
messages: Belongs to the GARS family.

598659:NAMH RS00890
gene id: 598659:NAMH_RS00890
uniprot id: B9L7J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

598659:NAMH RS01990
gene id: 598659:NAMH_RS01990
uniprot id: B9L867
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

598659:NAMH RS03095
gene id: 598659:NAMH_RS03095
uniprot id: B9L8T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

598659:NAMH RS02995
gene id: 598659:NAMH_RS02995
uniprot id: B9L8R0
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS01925
gene id: 598659:NAMH_RS01925
uniprot id: B9L854
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

598659:NAMH RS06710
gene id: 598659:NAMH_RS06710
uniprot id: B9L5W9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

598659:NAMH RS02555
gene id: 598659:NAMH_RS02555
uniprot id: B9L8H4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS07905
gene id: 598659:NAMH_RS07905
uniprot id: B9L6K5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

598659:NAMH RS06080
gene id: 598659:NAMH_RS06080
uniprot id: B9L5I8
names: Similarity
messages: Belongs to the class-I fumarase family.

598659:NAMH RS06465
gene id: 598659:NAMH_RS06465
uniprot id: B9L5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

598659:NAMH RS00560
gene id: 598659:NAMH_RS00560
uniprot id: B9L7E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

598659:NAMH RS00145
gene id: 598659:NAMH_RS00145
uniprot id: B9L763
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS03160
gene id: 598659:NAMH_RS03160
uniprot id: B9L8U4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

598659:NAMH RS05855
gene id: 598659:NAMH_RS05855
uniprot id: B9LAC3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

598659:NAMH RS02795
gene id: 598659:NAMH_RS02795
uniprot id: B9L8M0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

598659:NAMH RS05195
gene id: 598659:NAMH_RS05195
uniprot id: B9L9Z6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

598659:NAMH RS06095
gene id: 598659:NAMH_RS06095
uniprot id: B9L5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

598659:NAMH RS00845
gene id: 598659:NAMH_RS00845
uniprot id: B9L7I9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

598659:NAMH RS04655
gene id: 598659:NAMH_RS04655
uniprot id: B9L9N6
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS01675
gene id: 598659:NAMH_RS01675
uniprot id: B9L803
names: Similarity
messages: Belongs to the IMPACT family.

598659:NAMH RS02300
gene id: 598659:NAMH_RS02300
uniprot id: B9L8C3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

598659:NAMH RS07980
gene id: 598659:NAMH_RS07980
uniprot id: B9L6L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

598659:NAMH RS06375
gene id: 598659:NAMH_RS06375
uniprot id: B9L5P7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

598659:NAMH RS07920
gene id: 598659:NAMH_RS07920
uniprot id: B9L6K8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

598659:NAMH RS05285
gene id: 598659:NAMH_RS05285
uniprot id: B9LA14
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS06065
gene id: 598659:NAMH_RS06065
uniprot id: B9L5I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

598659:NAMH RS00505
gene id: 598659:NAMH_RS00505
uniprot id: B9L7D0
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

598659:NAMH RS08995
gene id: 598659:NAMH_RS08995
uniprot id: B9L9I5
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS05485
gene id: 598659:NAMH_RS05485
uniprot id: B9LA51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

598659:NAMH RS07160
gene id: 598659:NAMH_RS07160
uniprot id: B9L659
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

598659:NAMH RS03660
gene id: 598659:NAMH_RS03660
uniprot id: B9L934
names: Similarity
messages: Belongs to the HypD family.

598659:NAMH RS08350
gene id: 598659:NAMH_RS08350
uniprot id: B9L6U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

598659:NAMH RS04710
gene id: 598659:NAMH_RS04710
uniprot id: B9L9P8
names: Similarity
messages: Belongs to the peptidase M16 family.

598659:NAMH RS02590
gene id: 598659:NAMH_RS02590
uniprot id: B9L8I1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS03765
gene id: 598659:NAMH_RS03765
uniprot id: B9L954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS04470
gene id: 598659:NAMH_RS04470
uniprot id: B9L9J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS05685
gene id: 598659:NAMH_RS05685
uniprot id: B9LA90
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

598659:NAMH RS03575
gene id: 598659:NAMH_RS03575
uniprot id: B9L919
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

598659:NAMH RS01635
gene id: 598659:NAMH_RS01635
uniprot id: B9L7Z5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

598659:NAMH RS04125
gene id: 598659:NAMH_RS04125
uniprot id: B9L9C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

598659:NAMH RS00390
gene id: 598659:NAMH_RS00390
uniprot id: B9L7B1
names: Similarity
messages: Belongs to the leucine-binding protein family.

598659:NAMH RS02085
gene id: 598659:NAMH_RS02085
uniprot id: B9L885
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

598659:NAMH RS00415
gene id: 598659:NAMH_RS00415
uniprot id: B9L7B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

598659:NAMH RS03425
gene id: 598659:NAMH_RS03425
uniprot id: B9L8Z4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS06510
gene id: 598659:NAMH_RS06510
uniprot id: B9L5S6
names: Similarity
messages: Belongs to the threonine synthase family.

598659:NAMH RS01475
gene id: 598659:NAMH_RS01475
uniprot id: B9L7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS04755
gene id: 598659:NAMH_RS04755
uniprot id: B9L9Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

598659:NAMH RS02730
gene id: 598659:NAMH_RS02730
uniprot id: B9L8K7
names: Similarity
messages: Belongs to the pyruvate kinase family.

598659:NAMH RS08970
gene id: 598659:NAMH_RS08970
uniprot id: B9L8Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

598659:NAMH RS04585
gene id: 598659:NAMH_RS04585
uniprot id: B9L9M2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

598659:NAMH RS06700
gene id: 598659:NAMH_RS06700
uniprot id: B9L5W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

598659:NAMH RS05695
gene id: 598659:NAMH_RS05695
uniprot id: B9LA92
names: Similarity
messages: Belongs to the DprA/Smf family.

598659:NAMH RS08080
gene id: 598659:NAMH_RS08080
uniprot id: B9L6N5
names: Similarity
messages: Belongs to the LOG family.

598659:NAMH RS05050
gene id: 598659:NAMH_RS05050
uniprot id: B9L9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

598659:NAMH RS06905
gene id: 598659:NAMH_RS06905
uniprot id: B9L608
names: Similarity
messages: Belongs to the RutC family.

598659:NAMH RS06665
gene id: 598659:NAMH_RS06665
uniprot id: B9L5V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

598659:NAMH RS04690
gene id: 598659:NAMH_RS04690
uniprot id: B9L9P4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

598659:NAMH RS05365
gene id: 598659:NAMH_RS05365
uniprot id: B9LA29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

598659:NAMH RS08580
gene id: 598659:NAMH_RS08580
uniprot id: B9L6Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

598659:NAMH RS07055
gene id: 598659:NAMH_RS07055
uniprot id: B9L638
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

598659:NAMH RS06970
gene id: 598659:NAMH_RS06970
uniprot id: B9L621
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

598659:NAMH RS08670
gene id: 598659:NAMH_RS08670
uniprot id: B9L6Z3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

598659:NAMH RS00140
gene id: 598659:NAMH_RS00140
uniprot id: B9L762
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

598659:NAMH RS05510
gene id: 598659:NAMH_RS05510
uniprot id: B9LA56
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

598659:NAMH RS05990
gene id: 598659:NAMH_RS05990
uniprot id: B9LAF0
names: Similarity
messages: Belongs to the aspartokinase family.

598659:NAMH RS06525
gene id: 598659:NAMH_RS06525
uniprot id: B9L5S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

598659:NAMH RS06965
gene id: 598659:NAMH_RS06965
uniprot id: B9L620
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS05720
gene id: 598659:NAMH_RS05720
uniprot id: B9LA97
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

598659:NAMH RS08285
gene id: 598659:NAMH_RS08285
uniprot id: B9L6S7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

598659:NAMH RS02290
gene id: 598659:NAMH_RS02290
uniprot id: B9L8C1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

598659:NAMH RS02210
gene id: 598659:NAMH_RS02210
uniprot id: B9L8A6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

598659:NAMH RS03895
gene id: 598659:NAMH_RS03895
uniprot id: B9L981
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS05225
gene id: 598659:NAMH_RS05225
uniprot id: B9LA02
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS04405
gene id: 598659:NAMH_RS04405
uniprot id: B9L9I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

598659:NAMH RS06035
gene id: 598659:NAMH_RS06035
uniprot id: B9L5H9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

598659:NAMH RS07085
gene id: 598659:NAMH_RS07085
uniprot id: B9L644
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

598659:NAMH RS07840
gene id: 598659:NAMH_RS07840
uniprot id: B9L6J2
names: Similarity
messages: Belongs to the ArsC family.

598659:NAMH RS04155
gene id: 598659:NAMH_RS04155
uniprot id: B9L9D4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

598659:NAMH RS01440
gene id: 598659:NAMH_RS01440
uniprot id: B9L7V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

598659:NAMH RS07210
gene id: 598659:NAMH_RS07210
uniprot id: B9L669
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS05475
gene id: 598659:NAMH_RS05475
uniprot id: B9LA49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

598659:NAMH RS05530
gene id: 598659:NAMH_RS05530
uniprot id: B9LA60
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

598659:NAMH RS03490
gene id: 598659:NAMH_RS03490
uniprot id: B9L907
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

598659:NAMH RS05730
gene id: 598659:NAMH_RS05730
uniprot id: B9LA99
names: Similarity
messages: Belongs to the MotB family.

598659:NAMH RS05470
gene id: 598659:NAMH_RS05470
uniprot id: B9LA48
names: Similarity
messages: Belongs to the GSP E family.

598659:NAMH RS01370
gene id: 598659:NAMH_RS01370
uniprot id: B9L7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

598659:NAMH RS04735
gene id: 598659:NAMH_RS04735
uniprot id: B9L9Q3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

598659:NAMH RS08060
gene id: 598659:NAMH_RS08060
uniprot id: B9L6N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

598659:NAMH RS07350
gene id: 598659:NAMH_RS07350
uniprot id: B9L695
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08840
gene id: 598659:NAMH_RS08840
uniprot id: B9L726
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS01770
gene id: 598659:NAMH_RS01770
uniprot id: B9L822
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

598659:NAMH RS05180
gene id: 598659:NAMH_RS05180
uniprot id: B9L9Z3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

598659:NAMH RS02305
gene id: 598659:NAMH_RS02305
uniprot id: B9L8C4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS05740
gene id: 598659:NAMH_RS05740
uniprot id: B9LAA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

598659:NAMH RS03995
gene id: 598659:NAMH_RS03995
uniprot id: B9L9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

598659:NAMH RS01565
gene id: 598659:NAMH_RS01565
uniprot id: B9L7Y1
names: Similarity
messages: Belongs to the ParB family.

598659:NAMH RS08620
gene id: 598659:NAMH_RS08620
uniprot id: B9L6Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

598659:NAMH RS08835
gene id: 598659:NAMH_RS08835
uniprot id: B9L725
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

598659:NAMH RS07665
gene id: 598659:NAMH_RS07665
uniprot id: B9L6F8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

598659:NAMH RS04085
gene id: 598659:NAMH_RS04085
uniprot id: B9L9C0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

598659:NAMH RS07985
gene id: 598659:NAMH_RS07985
uniprot id: B9L6L6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

598659:NAMH RS01575
gene id: 598659:NAMH_RS01575
uniprot id: B9L7Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

598659:NAMH RS03205
gene id: 598659:NAMH_RS03205
uniprot id: B9L8U9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

598659:NAMH RS04515
gene id: 598659:NAMH_RS04515
uniprot id: B9L9K8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

598659:NAMH RS00330
gene id: 598659:NAMH_RS00330
uniprot id: B9L799
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS02310
gene id: 598659:NAMH_RS02310
uniprot id: B9L8C5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

598659:NAMH RS08290
gene id: 598659:NAMH_RS08290
uniprot id: B9L6S8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

598659:NAMH RS05290
gene id: 598659:NAMH_RS05290
uniprot id: B9LA15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

598659:NAMH RS06820
gene id: 598659:NAMH_RS06820
uniprot id: B9L5Z1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

598659:NAMH RS04195
gene id: 598659:NAMH_RS04195
uniprot id: B9L9E3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

598659:NAMH RS04320
gene id: 598659:NAMH_RS04320
uniprot id: B9L9G9
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00940
gene id: 598659:NAMH_RS00940
uniprot id: B9L7K6
names: Similarity
messages: Belongs to the UPF0597 family.

598659:NAMH RS02920
gene id: 598659:NAMH_RS02920
uniprot id: B9L8P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS00840
gene id: 598659:NAMH_RS00840
uniprot id: B9L7I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

598659:NAMH RS08880
gene id: 598659:NAMH_RS08880
uniprot id: B9L734
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

598659:NAMH RS06540
gene id: 598659:NAMH_RS06540
uniprot id: B9L5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

598659:NAMH RS04810
gene id: 598659:NAMH_RS04810
uniprot id: B9L9R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

598659:NAMH RS01610
gene id: 598659:NAMH_RS01610
uniprot id: B9L7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

598659:NAMH RS03045
gene id: 598659:NAMH_RS03045
uniprot id: B9L8S1
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

598659:NAMH RS04490
gene id: 598659:NAMH_RS04490
uniprot id: B9L9K3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

598659:NAMH RS01685
gene id: 598659:NAMH_RS01685
uniprot id: B9L805
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08845
gene id: 598659:NAMH_RS08845
uniprot id: B9L727
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS06855
gene id: 598659:NAMH_RS06855
uniprot id: B9L5Z8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

598659:NAMH RS02470
gene id: 598659:NAMH_RS02470
uniprot id: B9L8F7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

598659:NAMH RS04090
gene id: 598659:NAMH_RS04090
uniprot id: B9L9C1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

598659:NAMH RS00875
gene id: 598659:NAMH_RS00875
uniprot id: B9L7J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

598659:NAMH RS06500
gene id: 598659:NAMH_RS06500
uniprot id: B9L5S4
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08130
gene id: 598659:NAMH_RS08130
uniprot id: B9L6P5
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS03375
gene id: 598659:NAMH_RS03375
uniprot id: B9L8Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

598659:NAMH RS06390
gene id: 598659:NAMH_RS06390
uniprot id: B9L5Q0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

598659:NAMH RS03345
gene id: 598659:NAMH_RS03345
uniprot id: B9L8X8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

598659:NAMH RS00185
gene id: 598659:NAMH_RS00185
uniprot id: B9L771
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

598659:NAMH RS00305
gene id: 598659:NAMH_RS00305
uniprot id: B9L794
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

598659:NAMH RS06155
gene id: 598659:NAMH_RS06155
uniprot id: B9L5K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS05675
gene id: 598659:NAMH_RS05675
uniprot id: B9LA88
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS08045
gene id: 598659:NAMH_RS08045
uniprot id: B9L6M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

598659:NAMH RS00555
gene id: 598659:NAMH_RS00555
uniprot id: B9L7E0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

598659:NAMH RS04805
gene id: 598659:NAMH_RS04805
uniprot id: B9L9R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

598659:NAMH RS07440
gene id: 598659:NAMH_RS07440
uniprot id: B9L6B5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

598659:NAMH RS07540
gene id: 598659:NAMH_RS07540
uniprot id: B9L6D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

598659:NAMH RS03405
gene id: 598659:NAMH_RS03405
uniprot id: B9L8Z0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

598659:NAMH RS07415
gene id: 598659:NAMH_RS07415
uniprot id: B9L6B0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

598659:NAMH RS06005
gene id: 598659:NAMH_RS06005
uniprot id: B9LAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

598659:NAMH RS05230
gene id: 598659:NAMH_RS05230
uniprot id: B9LA03
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS01255
gene id: 598659:NAMH_RS01255
uniprot id: B9L7R9
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

598659:NAMH RS02480
gene id: 598659:NAMH_RS02480
uniprot id: B9L8F9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

598659:NAMH RS00035
gene id: 598659:NAMH_RS00035
uniprot id: B9L741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

598659:NAMH RS05830
gene id: 598659:NAMH_RS05830
uniprot id: B9LAB9
names: Similarity
messages: Belongs to the bacterial secretin family.

598659:NAMH RS07190
gene id: 598659:NAMH_RS07190
uniprot id: B9L665
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

598659:NAMH RS06135
gene id: 598659:NAMH_RS06135
uniprot id: B9L5J9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS00575
gene id: 598659:NAMH_RS00575
uniprot id: B9L7E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

598659:NAMH RS00765
gene id: 598659:NAMH_RS00765
uniprot id: B9L7I2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

598659:NAMH RS03065
gene id: 598659:NAMH_RS03065
uniprot id: B9L8S5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

598659:NAMH RS06530
gene id: 598659:NAMH_RS06530
uniprot id: B9L5T0
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

598659:NAMH RS01445
gene id: 598659:NAMH_RS01445
uniprot id: B9L7V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

598659:NAMH RS01285
gene id: 598659:NAMH_RS01285
uniprot id: B9L7S5
names: Similarity
messages: Belongs to the UPF0102 family.

598659:NAMH RS08395
gene id: 598659:NAMH_RS08395
uniprot id: B9L6U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

598659:NAMH RS01430
gene id: 598659:NAMH_RS01430
uniprot id: B9L7V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

598659:NAMH RS01070
gene id: 598659:NAMH_RS01070
uniprot id: B9L7N2
names: Similarity
messages: Belongs to the P(II) protein family.

598659:NAMH RS00025
gene id: 598659:NAMH_RS00025
uniprot id: B9L739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

598659:NAMH RS08375
gene id: 598659:NAMH_RS08375
uniprot id: B9L6U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

598659:NAMH RS00680
gene id: 598659:NAMH_RS00680
uniprot id: B9L7G5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

598659:NAMH RS07895
gene id: 598659:NAMH_RS07895
uniprot id: B9L6K3
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

598659:NAMH RS02750
gene id: 598659:NAMH_RS02750
uniprot id: B9L8L1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Periplasm

598659:NAMH RS00895
gene id: 598659:NAMH_RS00895
uniprot id: B9L7J7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

598659:NAMH RS07935
gene id: 598659:NAMH_RS07935
uniprot id: B9L6L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

598659:NAMH RS08525
gene id: 598659:NAMH_RS08525
uniprot id: B9L6X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

598659:NAMH RS02600
gene id: 598659:NAMH_RS02600
uniprot id: B9L8I3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

598659:NAMH RS06920
gene id: 598659:NAMH_RS06920
uniprot id: B9L611
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

598659:NAMH RS07995
gene id: 598659:NAMH_RS07995
uniprot id: B9L6L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

598659:NAMH RS07115
gene id: 598659:NAMH_RS07115
uniprot id: B9L650
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

598659:NAMH RS08720
gene id: 598659:NAMH_RS08720
uniprot id: B9L701
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS03600
gene id: 598659:NAMH_RS03600
uniprot id: B9L924
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS05235
gene id: 598659:NAMH_RS05235
uniprot id: B9LA04
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

598659:NAMH RS03845
gene id: 598659:NAMH_RS03845
uniprot id: B9L971
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

598659:NAMH RS02855
gene id: 598659:NAMH_RS02855
uniprot id: B9L8N2
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

598659:NAMH RS02275
gene id: 598659:NAMH_RS02275
uniprot id: B9L8B8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

598659:NAMH RS06535
gene id: 598659:NAMH_RS06535
uniprot id: B9L5T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

598659:NAMH RS01535
gene id: 598659:NAMH_RS01535
uniprot id: B9L7X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

598659:NAMH RS01290
gene id: 598659:NAMH_RS01290
uniprot id: B9L7S6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

598659:NAMH RS04020
gene id: 598659:NAMH_RS04020
uniprot id: B9L9A7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

598659:NAMH RS04500
gene id: 598659:NAMH_RS04500
uniprot id: B9L9K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

598659:NAMH RS05275
gene id: 598659:NAMH_RS05275
uniprot id: B9LA12
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

598659:NAMH RS02030
gene id: 598659:NAMH_RS02030
uniprot id: B9L875
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

598659:NAMH RS00900
gene id: 598659:NAMH_RS00900
uniprot id: B9L7J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

598659:NAMH RS05355
gene id: 598659:NAMH_RS05355
uniprot id: B9LA27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

598659:NAMH RS05295
gene id: 598659:NAMH_RS05295
uniprot id: B9LA16
names: Similarity
messages: Belongs to the hemerythrin family.

598659:NAMH RS02505
gene id: 598659:NAMH_RS02505
uniprot id: B9L8G4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

598659:NAMH RS07430
gene id: 598659:NAMH_RS07430
uniprot id: B9L6B3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

598659:NAMH RS04860
gene id: 598659:NAMH_RS04860
uniprot id: B9L9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

598659:NAMH RS04625
gene id: 598659:NAMH_RS04625
uniprot id: B9L9N0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS08030
gene id: 598659:NAMH_RS08030
uniprot id: B9L6M5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

598659:NAMH RS05640
gene id: 598659:NAMH_RS05640
uniprot id: B9LA81
names: Similarity
messages: Belongs to the GSP E family.

598659:NAMH RS07280
gene id: 598659:NAMH_RS07280
uniprot id: B9L683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

598659:NAMH RS05480
gene id: 598659:NAMH_RS05480
uniprot id: B9LA50
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

598659:NAMH RS01495
gene id: 598659:NAMH_RS01495
uniprot id: B9L7W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

598659:NAMH RS04080
gene id: 598659:NAMH_RS04080
uniprot id: B9L9B9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

598659:NAMH RS06995
gene id: 598659:NAMH_RS06995
uniprot id: B9L626
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

598659:NAMH RS06115
gene id: 598659:NAMH_RS06115
uniprot id: B9L5J5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

598659:NAMH RS03795
gene id: 598659:NAMH_RS03795
uniprot id: B9L961
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

598659:NAMH RS04370
gene id: 598659:NAMH_RS04370
uniprot id: B9L9H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

598659:NAMH RS06860
gene id: 598659:NAMH_RS06860
uniprot id: B9L5Z9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

598659:NAMH RS01150
gene id: 598659:NAMH_RS01150
uniprot id: B9L7P8
names: Similarity
messages: Belongs to the TrpF family.

598659:NAMH RS03855
gene id: 598659:NAMH_RS03855
uniprot id: B9L973
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

598659:NAMH RS04850
gene id: 598659:NAMH_RS04850
uniprot id: B9L9S4
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

598659:NAMH RS03810
gene id: 598659:NAMH_RS03810
uniprot id: B9L964
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

598659:NAMH RS06825
gene id: 598659:NAMH_RS06825
uniprot id: B9L5Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.

598659:NAMH RS03850
gene id: 598659:NAMH_RS03850
uniprot id: B9L972
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

598659:NAMH RS06690
gene id: 598659:NAMH_RS06690
uniprot id: B9L5W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

598659:NAMH RS04575
gene id: 598659:NAMH_RS04575
uniprot id: B9L9M0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.

598659:NAMH RS03730
gene id: 598659:NAMH_RS03730
uniprot id: B9L947
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08070
gene id: 598659:NAMH_RS08070
uniprot id: B9L6N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

598659:NAMH RS02665
gene id: 598659:NAMH_RS02665
uniprot id: B9L8J4
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS01335
gene id: 598659:NAMH_RS01335
uniprot id: B9L7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

598659:NAMH RS07355
gene id: 598659:NAMH_RS07355
uniprot id: B9L696
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS04190
gene id: 598659:NAMH_RS04190
uniprot id: B9L9E2
names: Similarity
messages: Belongs to the MEMO1 family.

598659:NAMH RS04720
gene id: 598659:NAMH_RS04720
uniprot id: B9L9Q0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

598659:NAMH RS02880
gene id: 598659:NAMH_RS02880
uniprot id: B9L8N7
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

598659:NAMH RS03355
gene id: 598659:NAMH_RS03355
uniprot id: B9L8Y0
names: Similarity
messages: Belongs to the asparagine synthetase family.

598659:NAMH RS07825
gene id: 598659:NAMH_RS07825
uniprot id: B9L6I9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

598659:NAMH RS05520
gene id: 598659:NAMH_RS05520
uniprot id: B9LA58
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

598659:NAMH RS05605
gene id: 598659:NAMH_RS05605
uniprot id: B9LA74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

598659:NAMH RS04005
gene id: 598659:NAMH_RS04005
uniprot id: B9L9A4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

598659:NAMH RS05380
gene id: 598659:NAMH_RS05380
uniprot id: B9LA32
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

598659:NAMH RS02095
gene id: 598659:NAMH_RS02095
uniprot id: B9L887
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

598659:NAMH RS03650
gene id: 598659:NAMH_RS03650
uniprot id: B9L932
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

598659:NAMH RS07640
gene id: 598659:NAMH_RS07640
uniprot id: B9L6F3
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS03735
gene id: 598659:NAMH_RS03735
uniprot id: B9L948
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS07140
gene id: 598659:NAMH_RS07140
uniprot id: B9L655
names: Similarity
messages: Belongs to the UPF0235 family.

598659:NAMH RS00495
gene id: 598659:NAMH_RS00495
uniprot id: B9L7C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

598659:NAMH RS01230
gene id: 598659:NAMH_RS01230
uniprot id: B9L7R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

598659:NAMH RS04520
gene id: 598659:NAMH_RS04520
uniprot id: B9L9K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

598659:NAMH RS00490
gene id: 598659:NAMH_RS00490
uniprot id: B9L7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

598659:NAMH RS04550
gene id: 598659:NAMH_RS04550
uniprot id: B9L9L5
names: Similarity
messages: Belongs to the CvfB family.

598659:NAMH RS08085
gene id: 598659:NAMH_RS08085
uniprot id: B9L6N6
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00005
gene id: 598659:NAMH_RS00005
uniprot id: B9L735
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

598659:NAMH RS03240
gene id: 598659:NAMH_RS03240
uniprot id: B9L8V6
names: Similarity
messages: Belongs to the peptidase S41A family.

598659:NAMH RS01250
gene id: 598659:NAMH_RS01250
uniprot id: B9L7R8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

598659:NAMH RS07530
gene id: 598659:NAMH_RS07530
uniprot id: B9L6D2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

598659:NAMH RS00870
gene id: 598659:NAMH_RS00870
uniprot id: B9L7J2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

598659:NAMH RS04865
gene id: 598659:NAMH_RS04865
uniprot id: B9L9S7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

598659:NAMH RS02570
gene id: 598659:NAMH_RS02570
uniprot id: B9L8H7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS07970
gene id: 598659:NAMH_RS07970
uniprot id: B9L6L3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

598659:NAMH RS03015
gene id: 598659:NAMH_RS03015
uniprot id: B9L8R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

598659:NAMH RS08110
gene id: 598659:NAMH_RS08110
uniprot id: B9L6P1
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00910
gene id: 598659:NAMH_RS00910
uniprot id: B9L7K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

598659:NAMH RS01605
gene id: 598659:NAMH_RS01605
uniprot id: B9L7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS02790
gene id: 598659:NAMH_RS02790
uniprot id: B9L8L9
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS04675
gene id: 598659:NAMH_RS04675
uniprot id: B9L9P0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

598659:NAMH RS07775
gene id: 598659:NAMH_RS07775
uniprot id: B9L6H9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

598659:NAMH RS02225
gene id: 598659:NAMH_RS02225
uniprot id: B9L8A9
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS02510
gene id: 598659:NAMH_RS02510
uniprot id: B9L8G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

598659:NAMH RS05410
gene id: 598659:NAMH_RS05410
uniprot id: B9LA36
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

598659:NAMH RS03805
gene id: 598659:NAMH_RS03805
uniprot id: B9L963
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

598659:NAMH RS07605
gene id: 598659:NAMH_RS07605
uniprot id: B9L6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

598659:NAMH RS00180
gene id: 598659:NAMH_RS00180
uniprot id: B9L770
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

598659:NAMH RS06890
gene id: 598659:NAMH_RS06890
uniprot id: B9L605
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

598659:NAMH RS02835
gene id: 598659:NAMH_RS02835
uniprot id: B9L8M8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

598659:NAMH RS07930
gene id: 598659:NAMH_RS07930
uniprot id: B9L6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

598659:NAMH RS06075
gene id: 598659:NAMH_RS06075
uniprot id: B9L5I7
names: Similarity
messages: Belongs to the class-I fumarase family.

598659:NAMH RS04260
gene id: 598659:NAMH_RS04260
uniprot id: B9L9F6
names: Subcellular Location Annotation
messages: Cytoplasm

598659:NAMH RS03030
gene id: 598659:NAMH_RS03030
uniprot id: B9L8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

598659:NAMH RS02805
gene id: 598659:NAMH_RS02805
uniprot id: B9L8M2
names: Similarity
messages: Belongs to the ALAD family.

598659:NAMH RS04095
gene id: 598659:NAMH_RS04095
uniprot id: B9L9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

598659:NAMH RS06800
gene id: 598659:NAMH_RS06800
uniprot id: B9L5Y7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

598659:NAMH RS01225
gene id: 598659:NAMH_RS01225
uniprot id: B9L7R3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS01585
gene id: 598659:NAMH_RS01585
uniprot id: B9L7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

598659:NAMH RS01000
gene id: 598659:NAMH_RS01000
uniprot id: B9L7L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

598659:NAMH RS05715
gene id: 598659:NAMH_RS05715
uniprot id: B9LA96
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

598659:NAMH RS04820
gene id: 598659:NAMH_RS04820
uniprot id: B9L9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

598659:NAMH RS00355
gene id: 598659:NAMH_RS00355
uniprot id: B9L7A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

598659:NAMH RS03960
gene id: 598659:NAMH_RS03960
uniprot id: B9L994
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00965
gene id: 598659:NAMH_RS00965
uniprot id: B9L7L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

598659:NAMH RS05650
gene id: 598659:NAMH_RS05650
uniprot id: B9LA83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS08725
gene id: 598659:NAMH_RS08725
uniprot id: B9L702
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS08860
gene id: 598659:NAMH_RS08860
uniprot id: B9L730
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

598659:NAMH RS04495
gene id: 598659:NAMH_RS04495
uniprot id: B9L9K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

598659:NAMH RS03265
gene id: 598659:NAMH_RS03265
uniprot id: B9L8W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

598659:NAMH RS01810
gene id: 598659:NAMH_RS01810
uniprot id: B9L830
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS03590
gene id: 598659:NAMH_RS03590
uniprot id: B9L922
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS05450
gene id: 598659:NAMH_RS05450
uniprot id: B9LA44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

598659:NAMH RS05280
gene id: 598659:NAMH_RS05280
uniprot id: B9LA13
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

598659:NAMH RS03385
gene id: 598659:NAMH_RS03385
uniprot id: B9L8Y6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

598659:NAMH RS02270
gene id: 598659:NAMH_RS02270
uniprot id: B9L8B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

598659:NAMH RS06895
gene id: 598659:NAMH_RS06895
uniprot id: B9L606
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

598659:NAMH RS08005
gene id: 598659:NAMH_RS08005
uniprot id: B9L6M0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

598659:NAMH RS01215
gene id: 598659:NAMH_RS01215
uniprot id: B9L7R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS04925
gene id: 598659:NAMH_RS04925
uniprot id: B9L9U1
names: Similarity
messages: Belongs to the RibF family.

598659:NAMH RS06615
gene id: 598659:NAMH_RS06615
uniprot id: B9L5U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

598659:NAMH RS03315
gene id: 598659:NAMH_RS03315
uniprot id: B9L8X2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS08855
gene id: 598659:NAMH_RS08855
uniprot id: B9L729
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

598659:NAMH RS06955
gene id: 598659:NAMH_RS06955
uniprot id: B9L618
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS02425
gene id: 598659:NAMH_RS02425
uniprot id: B9L8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

598659:NAMH RS06805
gene id: 598659:NAMH_RS06805
uniprot id: B9L5Y8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

598659:NAMH RS02545
gene id: 598659:NAMH_RS02545
uniprot id: B9L8H2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

598659:NAMH RS03890
gene id: 598659:NAMH_RS03890
uniprot id: B9L980
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

598659:NAMH RS06880
gene id: 598659:NAMH_RS06880
uniprot id: B9L603
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

598659:NAMH RS04340
gene id: 598659:NAMH_RS04340
uniprot id: B9L9H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

598659:NAMH RS03585
gene id: 598659:NAMH_RS03585
uniprot id: B9L921
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

598659:NAMH RS03465
gene id: 598659:NAMH_RS03465
uniprot id: B9L902
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

598659:NAMH RS00125
gene id: 598659:NAMH_RS00125
uniprot id: B9L759
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

598659:NAMH RS02800
gene id: 598659:NAMH_RS02800
uniprot id: B9L8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS06545
gene id: 598659:NAMH_RS06545
uniprot id: B9L5T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

598659:NAMH RS05565
gene id: 598659:NAMH_RS05565
uniprot id: B9LA66
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

598659:NAMH RS03815
gene id: 598659:NAMH_RS03815
uniprot id: B9L965
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

598659:NAMH RS06365
gene id: 598659:NAMH_RS06365
uniprot id: B9L5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS03390
gene id: 598659:NAMH_RS03390
uniprot id: B9L8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

598659:NAMH RS04970
gene id: 598659:NAMH_RS04970
uniprot id: B9L9V0
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

598659:NAMH RS07990
gene id: 598659:NAMH_RS07990
uniprot id: B9L6L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

598659:NAMH RS02360
gene id: 598659:NAMH_RS02360
uniprot id: B9L8D5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

598659:NAMH RS08410
gene id: 598659:NAMH_RS08410
uniprot id: B9L6V1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

598659:NAMH RS06555
gene id: 598659:NAMH_RS06555
uniprot id: B9L5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

598659:NAMH RS06940
gene id: 598659:NAMH_RS06940
uniprot id: B9L615
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

598659:NAMH RS04530
gene id: 598659:NAMH_RS04530
uniprot id: B9L9L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

598659:NAMH RS05765
gene id: 598659:NAMH_RS05765
uniprot id: B9LAA6
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08850
gene id: 598659:NAMH_RS08850
uniprot id: B9L728
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

598659:NAMH RS07235
gene id: 598659:NAMH_RS07235
uniprot id: B9L674
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

598659:NAMH RS06740
gene id: 598659:NAMH_RS06740
uniprot id: B9L5X5
names: Similarity
messages: Belongs to the GSP E family.

598659:NAMH RS05465
gene id: 598659:NAMH_RS05465
uniprot id: B9LA47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

598659:NAMH RS03910
gene id: 598659:NAMH_RS03910
uniprot id: B9L984
names: Similarity
messages: Belongs to the sigma-54 factor family.

598659:NAMH RS04270
gene id: 598659:NAMH_RS04270
uniprot id: B9L9F9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

598659:NAMH RS05250
gene id: 598659:NAMH_RS05250
uniprot id: B9LA07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS07720
gene id: 598659:NAMH_RS07720
uniprot id: B9L6G9
names: Similarity
messages: Belongs to the glutamate synthase family.

598659:NAMH RS02550
gene id: 598659:NAMH_RS02550
uniprot id: B9L8H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

598659:NAMH RS01945
gene id: 598659:NAMH_RS01945
uniprot id: B9L858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

598659:NAMH RS08200
gene id: 598659:NAMH_RS08200
uniprot id: B9L6Q9
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

598659:NAMH RS08040
gene id: 598659:NAMH_RS08040
uniprot id: B9L6M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

598659:NAMH RS01545
gene id: 598659:NAMH_RS01545
uniprot id: B9L7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

598659:NAMH RS03820
gene id: 598659:NAMH_RS03820
uniprot id: B9L966
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

598659:NAMH RS01590
gene id: 598659:NAMH_RS01590
uniprot id: B9L7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

598659:NAMH RS07915
gene id: 598659:NAMH_RS07915
uniprot id: B9L6K7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

598659:NAMH RS06205
gene id: 598659:NAMH_RS06205
uniprot id: B9L5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

598659:NAMH RS00465
gene id: 598659:NAMH_RS00465
uniprot id: B9L7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

598659:NAMH RS01570
gene id: 598659:NAMH_RS01570
uniprot id: B9L7Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

598659:NAMH RS04475
gene id: 598659:NAMH_RS04475
uniprot id: B9L9K0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

598659:NAMH RS07365
gene id: 598659:NAMH_RS07365
uniprot id: B9L698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

598659:NAMH RS00200
gene id: 598659:NAMH_RS00200
uniprot id: B9L774
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

598659:NAMH RS07250
gene id: 598659:NAMH_RS07250
uniprot id: B9L677
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

598659:NAMH RS00030
gene id: 598659:NAMH_RS00030
uniprot id: B9L740
names: Similarity
messages: Belongs to the GSP E family.

598659:NAMH RS06300
gene id: 598659:NAMH_RS06300
uniprot id: B9L5N2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

598659:NAMH RS06175
gene id: 598659:NAMH_RS06175
uniprot id: B9L5K7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

598659:NAMH RS07495
gene id: 598659:NAMH_RS07495
uniprot id: B9L6C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

598659:NAMH RS05325
gene id: 598659:NAMH_RS05325
uniprot id: B9LA22
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

598659:NAMH RS05395
gene id: 598659:NAMH_RS05395
uniprot id: B9LA34
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

598659:NAMH RS04910
gene id: 598659:NAMH_RS04910
uniprot id: B9L9T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

598659:NAMH RS06760
gene id: 598659:NAMH_RS06760
uniprot id: B9L5X9
names: Similarity
messages: Belongs to the bacterial secretin family.

598659:NAMH RS00460
gene id: 598659:NAMH_RS00460
uniprot id: B9L7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

598659:NAMH RS07000
gene id: 598659:NAMH_RS07000
uniprot id: B9L627
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

598659:NAMH RS02025
gene id: 598659:NAMH_RS02025
uniprot id: B9L874
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS03430
gene id: 598659:NAMH_RS03430
uniprot id: B9L8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

598659:NAMH RS01890
gene id: 598659:NAMH_RS01890
uniprot id: B9L847
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

598659:NAMH RS05440
gene id: 598659:NAMH_RS05440
uniprot id: B9LA42
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

598659:NAMH RS02450
gene id: 598659:NAMH_RS02450
uniprot id: B9L8F3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

598659:NAMH RS08075
gene id: 598659:NAMH_RS08075
uniprot id: B9L6N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

598659:NAMH RS05155
gene id: 598659:NAMH_RS05155
uniprot id: B9L9Y8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

598659:NAMH RS08065
gene id: 598659:NAMH_RS08065
uniprot id: B9L6N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

598659:NAMH RS01065
gene id: 598659:NAMH_RS01065
uniprot id: B9L7N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS02190
gene id: 598659:NAMH_RS02190
uniprot id: B9L8A2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

598659:NAMH RS02710
gene id: 598659:NAMH_RS02710
uniprot id: B9L8K3
names: Similarity
messages: Belongs to the UPF0763 family.

598659:NAMH RS01625
gene id: 598659:NAMH_RS01625
uniprot id: B9L7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

598659:NAMH RS04795
gene id: 598659:NAMH_RS04795
uniprot id: B9L9R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS03920
gene id: 598659:NAMH_RS03920
uniprot id: B9L986
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

598659:NAMH RS04360
gene id: 598659:NAMH_RS04360
uniprot id: B9L9H7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS00450
gene id: 598659:NAMH_RS00450
uniprot id: B9L7B9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS04980
gene id: 598659:NAMH_RS04980
uniprot id: B9L9V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

598659:NAMH RS06145
gene id: 598659:NAMH_RS06145
uniprot id: B9L5K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

598659:NAMH RS04075
gene id: 598659:NAMH_RS04075
uniprot id: B9L9B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

598659:NAMH RS05620
gene id: 598659:NAMH_RS05620
uniprot id: B9LA77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

598659:NAMH RS04985
gene id: 598659:NAMH_RS04985
uniprot id: B9L9V3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS03225
gene id: 598659:NAMH_RS03225
uniprot id: B9L8V3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

598659:NAMH RS06900
gene id: 598659:NAMH_RS06900
uniprot id: B9L607
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

598659:NAMH RS07300
gene id: 598659:NAMH_RS07300
uniprot id: B9L687
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

598659:NAMH RS03530
gene id: 598659:NAMH_RS03530
uniprot id: B9L915
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS03755
gene id: 598659:NAMH_RS03755
uniprot id: B9L952
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

598659:NAMH RS05955
gene id: 598659:NAMH_RS05955
uniprot id: B9LAE3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

598659:NAMH RS07500
gene id: 598659:NAMH_RS07500
uniprot id: B9L6C7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

598659:NAMH RS00275
gene id: 598659:NAMH_RS00275
uniprot id: B9L788
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

598659:NAMH RS05140
gene id: 598659:NAMH_RS05140
uniprot id: B9L9Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

598659:NAMH RS05005
gene id: 598659:NAMH_RS05005
uniprot id: B9L9V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

598659:NAMH RS03535
gene id: 598659:NAMH_RS03535
uniprot id: B9L916
names: Similarity
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

598659:NAMH RS06230
gene id: 598659:NAMH_RS06230
uniprot id: B9L5L8
names: Similarity
messages: Belongs to the bacterial secretin family.

598659:NAMH RS02720
gene id: 598659:NAMH_RS02720
uniprot id: B9L8K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

598659:NAMH RS00665
gene id: 598659:NAMH_RS00665
uniprot id: B9L7G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

598659:NAMH RS03655
gene id: 598659:NAMH_RS03655
uniprot id: B9L933
names: Similarity
messages: Belongs to the HupF/HypC family.

598659:NAMH RS07595
gene id: 598659:NAMH_RS07595
uniprot id: B9L6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

598659:NAMH RS00660
gene id: 598659:NAMH_RS00660
uniprot id: B9L7G1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

598659:NAMH RS03055
gene id: 598659:NAMH_RS03055
uniprot id: B9L8S3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

598659:NAMH RS03025
gene id: 598659:NAMH_RS03025
uniprot id: B9L8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

598659:NAMH RS01705
gene id: 598659:NAMH_RS01705
uniprot id: B9L809
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS03300
gene id: 598659:NAMH_RS03300
uniprot id: B9L8W8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

598659:NAMH RS08510
gene id: 598659:NAMH_RS08510
uniprot id: B9L6X1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

598659:NAMH RS05120
gene id: 598659:NAMH_RS05120
uniprot id: B9L9Y1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

598659:NAMH RS05415
gene id: 598659:NAMH_RS05415
uniprot id: B9LA37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

598659:NAMH RS00605
gene id: 598659:NAMH_RS00605
uniprot id: B9L7F0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS08000
gene id: 598659:NAMH_RS08000
uniprot id: B9L6L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

598659:NAMH RS00915
gene id: 598659:NAMH_RS00915
uniprot id: B9L7K1
names: Similarity
messages: Belongs to the NadC/ModD family.

598659:NAMH RS08280
gene id: 598659:NAMH_RS08280
uniprot id: B9L6S6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

598659:NAMH RS08365
gene id: 598659:NAMH_RS08365
uniprot id: B9L6U2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

598659:NAMH RS08035
gene id: 598659:NAMH_RS08035
uniprot id: B9L6M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

598659:NAMH RS05575
gene id: 598659:NAMH_RS05575
uniprot id: B9LA68
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS03105
gene id: 598659:NAMH_RS03105
uniprot id: B9L8T3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

598659:NAMH RS01730
gene id: 598659:NAMH_RS01730
uniprot id: B9L814
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08815
gene id: 598659:NAMH_RS08815
uniprot id: B9L721
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

598659:NAMH RS05660
gene id: 598659:NAMH_RS05660
uniprot id: B9LA85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

598659:NAMH RS06575
gene id: 598659:NAMH_RS06575
uniprot id: B9L5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

598659:NAMH RS06010
gene id: 598659:NAMH_RS06010
uniprot id: B9LAF4
names: Similarity
messages: Belongs to the TrpC family.

598659:NAMH RS06340
gene id: 598659:NAMH_RS06340
uniprot id: B9L5P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

598659:NAMH RS00165
gene id: 598659:NAMH_RS00165
uniprot id: B9L767
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

598659:NAMH RS08340
gene id: 598659:NAMH_RS08340
uniprot id: B9L6T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

598659:NAMH RS08875
gene id: 598659:NAMH_RS08875
uniprot id: B9L733
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

598659:NAMH RS00475
gene id: 598659:NAMH_RS00475
uniprot id: B9L7C4
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

598659:NAMH RS04390
gene id: 598659:NAMH_RS04390
uniprot id: B9L9I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

598659:NAMH RS02390
gene id: 598659:NAMH_RS02390
uniprot id: B9L8E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

598659:NAMH RS08125
gene id: 598659:NAMH_RS08125
uniprot id: B9L6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

598659:NAMH RS00345
gene id: 598659:NAMH_RS00345
uniprot id: B9L7A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

598659:NAMH RS01870
gene id: 598659:NAMH_RS01870
uniprot id: B9L843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS01965
gene id: 598659:NAMH_RS01965
uniprot id: B9L862
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08145
gene id: 598659:NAMH_RS08145
uniprot id: B9L6P8
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS05625
gene id: 598659:NAMH_RS05625
uniprot id: B9LA78
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

598659:NAMH RS06850
gene id: 598659:NAMH_RS06850
uniprot id: B9L5Z7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

598659:NAMH RS08930
gene id: 598659:NAMH_RS08930
uniprot id: B9L821
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

598659:NAMH RS09045
gene id: 598659:NAMH_RS09045
uniprot id: B9L6W9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

598659:NAMH RS01245
gene id: 598659:NAMH_RS01245
uniprot id: B9L7R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

598659:NAMH RS07965
gene id: 598659:NAMH_RS07965
uniprot id: B9L6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

598659:NAMH RS07800
gene id: 598659:NAMH_RS07800
uniprot id: B9L6I4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS07490
gene id: 598659:NAMH_RS07490
uniprot id: B9L6C5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

598659:NAMH RS02220
gene id: 598659:NAMH_RS02220
uniprot id: B9L8A8
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

598659:NAMH RS05260
gene id: 598659:NAMH_RS05260
uniprot id: B9LA09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

598659:NAMH RS02925
gene id: 598659:NAMH_RS02925
uniprot id: B9L8P6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

598659:NAMH RS05645
gene id: 598659:NAMH_RS05645
uniprot id: B9LA82
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

598659:NAMH RS03970
gene id: 598659:NAMH_RS03970
uniprot id: B9L997
names: Similarity
messages: Belongs to the UPF0251 family.

598659:NAMH RS04010
gene id: 598659:NAMH_RS04010
uniprot id: B9L9A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

598659:NAMH RS03495
gene id: 598659:NAMH_RS03495
uniprot id: B9L908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS05770
gene id: 598659:NAMH_RS05770
uniprot id: B9LAA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS01390
gene id: 598659:NAMH_RS01390
uniprot id: B9L7U6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

598659:NAMH RS07445
gene id: 598659:NAMH_RS07445
uniprot id: B9L6B6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

598659:NAMH RS06265
gene id: 598659:NAMH_RS06265
uniprot id: B9L5M5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

598659:NAMH RS08400
gene id: 598659:NAMH_RS08400
uniprot id: B9L6U9
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08135
gene id: 598659:NAMH_RS08135
uniprot id: B9L6P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

598659:NAMH RS08210
gene id: 598659:NAMH_RS08210
uniprot id: B9L6R1
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

598659:NAMH RS06480
gene id: 598659:NAMH_RS06480
uniprot id: B9L5S0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

598659:NAMH RS00290
gene id: 598659:NAMH_RS00290
uniprot id: B9L791
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

598659:NAMH RS06625
gene id: 598659:NAMH_RS06625
uniprot id: B9L5V0
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

598659:NAMH RS08265
gene id: 598659:NAMH_RS08265
uniprot id: B9L6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS07330
gene id: 598659:NAMH_RS07330
uniprot id: B9L692
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

598659:NAMH RS08385
gene id: 598659:NAMH_RS08385
uniprot id: B9L6U6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

598659:NAMH RS03050
gene id: 598659:NAMH_RS03050
uniprot id: B9L8S2
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

598659:NAMH RS04730
gene id: 598659:NAMH_RS04730
uniprot id: B9L9Q2
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS02065
gene id: 598659:NAMH_RS02065
uniprot id: B9L881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS09165
gene id: 598659:NAMH_RS09165
uniprot id: B9L8Y3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

598659:NAMH RS01075
gene id: 598659:NAMH_RS01075
uniprot id: B9L7N3
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

598659:NAMH RS01275
gene id: 598659:NAMH_RS01275
uniprot id: B9L7S3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

598659:NAMH RS04220
gene id: 598659:NAMH_RS04220
uniprot id: B9L9E8
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00700
gene id: 598659:NAMH_RS00700
uniprot id: B9L7G9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

598659:NAMH RS02230
gene id: 598659:NAMH_RS02230
uniprot id: B9L8B0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

598659:NAMH RS08335
gene id: 598659:NAMH_RS08335
uniprot id: B9L6T7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

598659:NAMH RS00295
gene id: 598659:NAMH_RS00295
uniprot id: B9L792
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

598659:NAMH RS01760
gene id: 598659:NAMH_RS01760
uniprot id: B9L820
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

598659:NAMH RS05060
gene id: 598659:NAMH_RS05060
uniprot id: B9L9W8
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

598659:NAMH RS06450
gene id: 598659:NAMH_RS06450
uniprot id: B9L5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

598659:NAMH RS05905
gene id: 598659:NAMH_RS05905
uniprot id: B9LAD3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

598659:NAMH RS01345
gene id: 598659:NAMH_RS01345
uniprot id: B9L7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

598659:NAMH RS08490
gene id: 598659:NAMH_RS08490
uniprot id: B9L6W7
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS02715
gene id: 598659:NAMH_RS02715
uniprot id: B9L8K4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

598659:NAMH RS06185
gene id: 598659:NAMH_RS06185
uniprot id: B9L5K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS05145
gene id: 598659:NAMH_RS05145
uniprot id: B9L9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS03125
gene id: 598659:NAMH_RS03125
uniprot id: B9L8T7
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

598659:NAMH RS00650
gene id: 598659:NAMH_RS00650
uniprot id: B9L7F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

598659:NAMH RS08360
gene id: 598659:NAMH_RS08360
uniprot id: B9L6U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

598659:NAMH RS07320
gene id: 598659:NAMH_RS07320
uniprot id: B9L691
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

598659:NAMH RS06975
gene id: 598659:NAMH_RS06975
uniprot id: B9L622
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

598659:NAMH RS08345
gene id: 598659:NAMH_RS08345
uniprot id: B9L6T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

598659:NAMH RS08675
gene id: 598659:NAMH_RS08675
uniprot id: B9L6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatB family.
messages: Cell inner membrane

598659:NAMH RS08780
gene id: 598659:NAMH_RS08780
uniprot id: B9L714
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS05555
gene id: 598659:NAMH_RS05555
uniprot id: B9LA64
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

598659:NAMH RS06885
gene id: 598659:NAMH_RS06885
uniprot id: B9L604
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

598659:NAMH RS07170
gene id: 598659:NAMH_RS07170
uniprot id: B9L661
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

598659:NAMH RS07110
gene id: 598659:NAMH_RS07110
uniprot id: B9L649
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

598659:NAMH RS07010
gene id: 598659:NAMH_RS07010
uniprot id: B9L629
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

598659:NAMH RS02780
gene id: 598659:NAMH_RS02780
uniprot id: B9L8L7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

598659:NAMH RS00600
gene id: 598659:NAMH_RS00600
uniprot id: B9L7E9
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS04120
gene id: 598659:NAMH_RS04120
uniprot id: B9L9C7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

598659:NAMH RS08015
gene id: 598659:NAMH_RS08015
uniprot id: B9L6M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

598659:NAMH RS08205
gene id: 598659:NAMH_RS08205
uniprot id: B9L6R0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS01375
gene id: 598659:NAMH_RS01375
uniprot id: B9L7U3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

598659:NAMH RS00720
gene id: 598659:NAMH_RS00720
uniprot id: B9L7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

598659:NAMH RS01485
gene id: 598659:NAMH_RS01485
uniprot id: B9L7W5
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

598659:NAMH RS00540
gene id: 598659:NAMH_RS00540
uniprot id: B9L7D7
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00865
gene id: 598659:NAMH_RS00865
uniprot id: B9L7J1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

598659:NAMH RS01180
gene id: 598659:NAMH_RS01180
uniprot id: B9L7Q4
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00120
gene id: 598659:NAMH_RS00120
uniprot id: B9L758
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

598659:NAMH RS03365
gene id: 598659:NAMH_RS03365
uniprot id: B9L8Y2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

598659:NAMH RS02915
gene id: 598659:NAMH_RS02915
uniprot id: B9L8P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

598659:NAMH RS06380
gene id: 598659:NAMH_RS06380
uniprot id: B9L5P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

598659:NAMH RS01170
gene id: 598659:NAMH_RS01170
uniprot id: B9L7Q2
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

598659:NAMH RS06985
gene id: 598659:NAMH_RS06985
uniprot id: B9L624
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

598659:NAMH RS04435
gene id: 598659:NAMH_RS04435
uniprot id: B9L9J2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

598659:NAMH RS07285
gene id: 598659:NAMH_RS07285
uniprot id: B9L684
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

598659:NAMH RS01860
gene id: 598659:NAMH_RS01860
uniprot id: B9L840
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

598659:NAMH RS02490
gene id: 598659:NAMH_RS02490
uniprot id: B9L8G1
names: Similarity
messages: Belongs to the glutamine synthetase family.

598659:NAMH RS03010
gene id: 598659:NAMH_RS03010
uniprot id: B9L8R4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

598659:NAMH RS08025
gene id: 598659:NAMH_RS08025
uniprot id: B9L6M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

598659:NAMH RS07290
gene id: 598659:NAMH_RS07290
uniprot id: B9L685
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

598659:NAMH RS03230
gene id: 598659:NAMH_RS03230
uniprot id: B9L8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

598659:NAMH RS08055
gene id: 598659:NAMH_RS08055
uniprot id: B9L6N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

598659:NAMH RS00905
gene id: 598659:NAMH_RS00905
uniprot id: B9L7J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

598659:NAMH RS07135
gene id: 598659:NAMH_RS07135
uniprot id: B9L654
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

598659:NAMH RS07205
gene id: 598659:NAMH_RS07205
uniprot id: B9L668
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

598659:NAMH RS05705
gene id: 598659:NAMH_RS05705
uniprot id: B9LA94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

598659:NAMH RS07100
gene id: 598659:NAMH_RS07100
uniprot id: B9L647
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

598659:NAMH RS02080
gene id: 598659:NAMH_RS02080
uniprot id: B9L884
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

598659:NAMH RS03360
gene id: 598659:NAMH_RS03360
uniprot id: B9L8Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane

598659:NAMH RS03400
gene id: 598659:NAMH_RS03400
uniprot id: B9L8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

598659:NAMH RS02690
gene id: 598659:NAMH_RS02690
uniprot id: B9L8J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

598659:NAMH RS05455
gene id: 598659:NAMH_RS05455
uniprot id: B9LA45
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS02005
gene id: 598659:NAMH_RS02005
uniprot id: B9L870
names: Similarity
messages: Belongs to the UPF0047 family.

598659:NAMH RS05185
gene id: 598659:NAMH_RS05185
uniprot id: B9L9Z4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

598659:NAMH RS06085
gene id: 598659:NAMH_RS06085
uniprot id: B9L5I9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

598659:NAMH RS01915
gene id: 598659:NAMH_RS01915
uniprot id: B9L852
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS06960
gene id: 598659:NAMH_RS06960
uniprot id: B9L619
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

598659:NAMH RS01720
gene id: 598659:NAMH_RS01720
uniprot id: B9L812
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

598659:NAMH RS07900
gene id: 598659:NAMH_RS07900
uniprot id: B9L6K4
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

598659:NAMH RS06250
gene id: 598659:NAMH_RS06250
uniprot id: B9L5M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

598659:NAMH RS04430
gene id: 598659:NAMH_RS04430
uniprot id: B9L9J1
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS06650
gene id: 598659:NAMH_RS06650
uniprot id: B9L5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

598659:NAMH RS00405
gene id: 598659:NAMH_RS00405
uniprot id: B9L7B4
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS00015
gene id: 598659:NAMH_RS00015
uniprot id: B9L737
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

598659:NAMH RS01550
gene id: 598659:NAMH_RS01550
uniprot id: B9L7X8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

598659:NAMH RS06070
gene id: 598659:NAMH_RS06070
uniprot id: B9L5I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

598659:NAMH RS06210
gene id: 598659:NAMH_RS06210
uniprot id: B9L5L4
names: Subcellular Location Annotation
messages: Cytoplasm

598659:NAMH RS04395
gene id: 598659:NAMH_RS04395
uniprot id: B9L9I4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

598659:NAMH RS01805
gene id: 598659:NAMH_RS01805
uniprot id: B9L829
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

598659:NAMH RS03670
gene id: 598659:NAMH_RS03670
uniprot id: B9L936
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

598659:NAMH RS01835
gene id: 598659:NAMH_RS01835
uniprot id: B9L835
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

598659:NAMH RS07615
gene id: 598659:NAMH_RS07615
uniprot id: B9L6E8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

598659:NAMH RS00695
gene id: 598659:NAMH_RS00695
uniprot id: B9L7G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

598659:NAMH RS00385
gene id: 598659:NAMH_RS00385
uniprot id: B9L7B0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

598659:NAMH RS03435
gene id: 598659:NAMH_RS03435
uniprot id: B9L8Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

598659:NAMH RS02465
gene id: 598659:NAMH_RS02465
uniprot id: B9L8F6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

598659:NAMH RS04740
gene id: 598659:NAMH_RS04740
uniprot id: B9L9Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

598659:NAMH RS00955
gene id: 598659:NAMH_RS00955
uniprot id: B9L7K9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

598659:NAMH RS08010
gene id: 598659:NAMH_RS08010
uniprot id: B9L6M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

598659:NAMH RS06295
gene id: 598659:NAMH_RS06295
uniprot id: B9L5N1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

598659:NAMH RS03680
gene id: 598659:NAMH_RS03680
uniprot id: B9L938
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

598659:NAMH RS03415
gene id: 598659:NAMH_RS03415
uniprot id: B9L8Z2
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS08495
gene id: 598659:NAMH_RS08495
uniprot id: B9L6W8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS02955
gene id: 598659:NAMH_RS02955
uniprot id: B9L8Q2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

598659:NAMH RS08250
gene id: 598659:NAMH_RS08250
uniprot id: B9L6S0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

598659:NAMH RS00780
gene id: 598659:NAMH_RS00780
uniprot id: B9L7I5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

598659:NAMH RS04855
gene id: 598659:NAMH_RS04855
uniprot id: B9L9S5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

598659:NAMH RS04050
gene id: 598659:NAMH_RS04050
uniprot id: B9L9B3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

598659:NAMH RS00885
gene id: 598659:NAMH_RS00885
uniprot id: B9L7J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

598659:NAMH RS06870
gene id: 598659:NAMH_RS06870
uniprot id: B9L601
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

598659:NAMH RS00550
gene id: 598659:NAMH_RS00550
uniprot id: B9L7D9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

598659:NAMH RS01670
gene id: 598659:NAMH_RS01670
uniprot id: B9L802
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

598659:NAMH RS05890
gene id: 598659:NAMH_RS05890
uniprot id: B9LAD0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

598659:NAMH RS03880
gene id: 598659:NAMH_RS03880
uniprot id: B9L978
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

598659:NAMH RS03665
gene id: 598659:NAMH_RS03665
uniprot id: B9L935
names: Similarity
messages: Belongs to the HypE family.

598659:NAMH RS07815
gene id: 598659:NAMH_RS07815
uniprot id: B9L6I7
names: Similarity
messages: Belongs to the UPF0047 family.

598659:NAMH RS04700
gene id: 598659:NAMH_RS04700
uniprot id: B9L9P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

598659:NAMH RS03110
gene id: 598659:NAMH_RS03110
uniprot id: B9L8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

598659:NAMH RS01595
gene id: 598659:NAMH_RS01595
uniprot id: B9L7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

598659:NAMH RS01970
gene id: 598659:NAMH_RS01970
uniprot id: B9L863
names: Similarity
messages: Belongs to the P(II) protein family.

598659:NAMH RS04130
gene id: 598659:NAMH_RS04130
uniprot id: B9L9C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

598659:NAMH RS02735
gene id: 598659:NAMH_RS02735
uniprot id: B9L8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

598659:NAMH RS01460
gene id: 598659:NAMH_RS01460
uniprot id: B9L7W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

598659:NAMH RS08020
gene id: 598659:NAMH_RS08020
uniprot id: B9L6M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

598659:NAMH RS06630
gene id: 598659:NAMH_RS06630
uniprot id: B9L5V1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

598659:NAMH RS02525
gene id: 598659:NAMH_RS02525
uniprot id: B9L8G8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

598659:NAMH RS01435
gene id: 598659:NAMH_RS01435
uniprot id: B9L7V5
names: Similarity
messages: Belongs to the peptidase S49 family.

598659:NAMH RS02705
gene id: 598659:NAMH_RS02705
uniprot id: B9L8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

598659:NAMH RS07635
gene id: 598659:NAMH_RS07635
uniprot id: B9L6F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

598659:NAMH RS05505
gene id: 598659:NAMH_RS05505
uniprot id: B9LA55
names: Subcellular Location Annotation
messages: Membrane

598659:NAMH RS01600
gene id: 598659:NAMH_RS01600
uniprot id: B9L7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

598659:NAMH RS05725
gene id: 598659:NAMH_RS05725
uniprot id: B9LA98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

598659:NAMH RS06225
gene id: 598659:NAMH_RS06225
uniprot id: B9L5L7
names: Similarity
messages: Belongs to the GSP E family.

598659:NAMH RS00520
gene id: 598659:NAMH_RS00520
uniprot id: B9L7D3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.