589873:EP13 RS00930
gene id: 589873:EP13_RS00930
uniprot id: A0A075NS87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

589873:EP13 RS16045
gene id: 589873:EP13_RS16045
uniprot id: A0A075P9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

589873:EP13 RS06550
gene id: 589873:EP13_RS06550
uniprot id: A0A075NUV4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

589873:EP13 RS00175
gene id: 589873:EP13_RS00175
uniprot id: A0A075NUN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

589873:EP13 RS16950
gene id: 589873:EP13_RS16950
uniprot id: A0A075P5Y4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

589873:EP13 RS07080
gene id: 589873:EP13_RS07080
uniprot id: A0A075NV29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS12800
gene id: 589873:EP13_RS12800
uniprot id: A0A075P128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

589873:EP13 RS05350
gene id: 589873:EP13_RS05350
uniprot id: A0A075NXE1
names: Similarity
messages: Belongs to the PspA/IM30 family.

589873:EP13 RS14770
gene id: 589873:EP13_RS14770
uniprot id: A0A075P4N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS02810
gene id: 589873:EP13_RS02810
uniprot id: A0A075NW55
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

589873:EP13 RS18055
gene id: 589873:EP13_RS18055
uniprot id: A0A075PAY5
names: Function
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

589873:EP13 RS02790
gene id: 589873:EP13_RS02790
uniprot id: A0A075NW43
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

589873:EP13 RS14495
gene id: 589873:EP13_RS14495
uniprot id: A0A075P210
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

589873:EP13 RS16280
gene id: 589873:EP13_RS16280
uniprot id: A0A075PA22
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

589873:EP13 RS17215
gene id: 589873:EP13_RS17215
uniprot id: A0A075P624
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

589873:EP13 RS08725
gene id: 589873:EP13_RS08725
uniprot id: A0A075P676
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS15400
gene id: 589873:EP13_RS15400
uniprot id: A0A075P9P0
names: Similarity
messages: Belongs to the DEAD box helicase family.

589873:EP13 RS08865
gene id: 589873:EP13_RS08865
uniprot id: A0A075NW40
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

589873:EP13 RS18440
gene id: 589873:EP13_RS18440
uniprot id: A0A075P417
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

589873:EP13 RS02235
gene id: 589873:EP13_RS02235
uniprot id: A0A075NVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

589873:EP13 RS02135
gene id: 589873:EP13_RS02135
uniprot id: A0A075NSR2
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

589873:EP13 RS01680
gene id: 589873:EP13_RS01680
uniprot id: A0A358E2H8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS03990
gene id: 589873:EP13_RS03990
uniprot id: A0A075NWU0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

589873:EP13 RS08205
gene id: 589873:EP13_RS08205
uniprot id: A0A075P1B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

589873:EP13 RS00480
gene id: 589873:EP13_RS00480
uniprot id: A0A075P1Q4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS13765
gene id: 589873:EP13_RS13765
uniprot id: A0A075NYH4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

589873:EP13 RS11520
gene id: 589873:EP13_RS11520
uniprot id: A0A075P7P5
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

589873:EP13 RS09820
gene id: 589873:EP13_RS09820
uniprot id: A0A075NZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

589873:EP13 RS05575
gene id: 589873:EP13_RS05575
uniprot id: A0A075P051
names: Similarity
messages: Belongs to the DinB family.

589873:EP13 RS03610
gene id: 589873:EP13_RS03610
uniprot id: A0A075NZ64
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

589873:EP13 RS02100
gene id: 589873:EP13_RS02100
uniprot id: A0A075P2L1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS09480
gene id: 589873:EP13_RS09480
uniprot id: A0A075P6L1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS01540
gene id: 589873:EP13_RS01540
uniprot id: A0A075P2B6
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

589873:EP13 RS18790
gene id: 589873:EP13_RS18790
uniprot id: A0A075PBB9
names: Similarity
messages: Belongs to the UPF0234 family.

589873:EP13 RS17150
gene id: 589873:EP13_RS17150
uniprot id: A0A075PAH8
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

589873:EP13 RS09350
gene id: 589873:EP13_RS09350
uniprot id: A0A075NZF5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS00250
gene id: 589873:EP13_RS00250
uniprot id: A0A075NRT7
names: Similarity
messages: Belongs to the UPF0758 family.

589873:EP13 RS12295
gene id: 589873:EP13_RS12295
uniprot id: A0A075P0Y2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

589873:EP13 RS04900
gene id: 589873:EP13_RS04900
uniprot id: A0A075NXC2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

589873:EP13 RS05960
gene id: 589873:EP13_RS05960
uniprot id: A0A075NUL9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

589873:EP13 RS09805
gene id: 589873:EP13_RS09805
uniprot id: A0A075NZN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

589873:EP13 RS16660
gene id: 589873:EP13_RS16660
uniprot id: A0A075PA86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

589873:EP13 RS00240
gene id: 589873:EP13_RS00240
uniprot id: A0A075P1I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

589873:EP13 RS16725
gene id: 589873:EP13_RS16725
uniprot id: A0A075P054
names: Similarity
messages: Belongs to the group II decarboxylase family.

589873:EP13 RS12825
gene id: 589873:EP13_RS12825
uniprot id: A0A075P134
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

589873:EP13 RS02815
gene id: 589873:EP13_RS02815
uniprot id: A0A075P300
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

589873:EP13 RS16900
gene id: 589873:EP13_RS16900
uniprot id: A0A075P5X5
names: Similarity
messages: Belongs to the peptidase M13 family.

589873:EP13 RS16690
gene id: 589873:EP13_RS16690
uniprot id: A0A075P3J5
names: Similarity
messages: Belongs to the SfsA family.

589873:EP13 RS02880
gene id: 589873:EP13_RS02880
uniprot id: A0A075NT26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

589873:EP13 RS17900
gene id: 589873:EP13_RS17900
uniprot id: A0A075P474
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

589873:EP13 RS01840
gene id: 589873:EP13_RS01840
uniprot id: A0A075P2G6
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS08000
gene id: 589873:EP13_RS08000
uniprot id: A0A075NYM2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

589873:EP13 RS16520
gene id: 589873:EP13_RS16520
uniprot id: A0A075P5L6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

589873:EP13 RS04515
gene id: 589873:EP13_RS04515
uniprot id: A0A075NTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS16650
gene id: 589873:EP13_RS16650
uniprot id: A0A075P5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

589873:EP13 RS03970
gene id: 589873:EP13_RS03970
uniprot id: A0A075P3P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS03810
gene id: 589873:EP13_RS03810
uniprot id: A0A075NTK0
names: Similarity
messages: Belongs to the peptidase S1C family.

589873:EP13 RS10265
gene id: 589873:EP13_RS10265
uniprot id: A0A075P6Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

589873:EP13 RS14090
gene id: 589873:EP13_RS14090
uniprot id: A0A075P218
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

589873:EP13 RS10690
gene id: 589873:EP13_RS10690
uniprot id: A0A075P2D3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

589873:EP13 RS08300
gene id: 589873:EP13_RS08300
uniprot id: A0A075P1C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

589873:EP13 RS13805
gene id: 589873:EP13_RS13805
uniprot id: A0A075P8R8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

589873:EP13 RS07170
gene id: 589873:EP13_RS07170
uniprot id: A0A075P5E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS18115
gene id: 589873:EP13_RS18115
uniprot id: A0A075PAZ3
names: Similarity
messages: Belongs to the phosphoribulokinase family.

589873:EP13 RS14720
gene id: 589873:EP13_RS14720
uniprot id: A0A075P239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

589873:EP13 RS17140
gene id: 589873:EP13_RS17140
uniprot id: A0A075P3E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS07220
gene id: 589873:EP13_RS07220
uniprot id: A0A075P0Y3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

589873:EP13 RS12540
gene id: 589873:EP13_RS12540
uniprot id: A0A075P3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

589873:EP13 RS13250
gene id: 589873:EP13_RS13250
uniprot id: A0A075P3R7
names: Similarity
messages: Belongs to the nitroreductase family.

589873:EP13 RS14265
gene id: 589873:EP13_RS14265
uniprot id: A0A075P1Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS17630
gene id: 589873:EP13_RS17630
uniprot id: A0A075P677
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS00030
gene id: 589873:EP13_RS00030
uniprot id: A0A075P1E8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

589873:EP13 RS14855
gene id: 589873:EP13_RS14855
uniprot id: A0A075P261
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

589873:EP13 RS06680
gene id: 589873:EP13_RS06680
uniprot id: A0A075NUX0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

589873:EP13 RS16560
gene id: 589873:EP13_RS16560
uniprot id: A0A075PA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

589873:EP13 RS17510
gene id: 589873:EP13_RS17510
uniprot id: A0A350P9U6
names: Caution
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS16450
gene id: 589873:EP13_RS16450
uniprot id: A0A075PA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS14850
gene id: 589873:EP13_RS14850
uniprot id: A0A075P4P2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

589873:EP13 RS12335
gene id: 589873:EP13_RS12335
uniprot id: A0A075P0U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

589873:EP13 RS05160
gene id: 589873:EP13_RS05160
uniprot id: A0A075P4E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

589873:EP13 RS11230
gene id: 589873:EP13_RS11230
uniprot id: A0A075P075
names: Similarity
messages: Belongs to the pyruvate kinase family.

589873:EP13 RS04040
gene id: 589873:EP13_RS04040
uniprot id: A0A075NWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

589873:EP13 RS03345
gene id: 589873:EP13_RS03345
uniprot id: A0A075NWI9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

589873:EP13 RS08080
gene id: 589873:EP13_RS08080
uniprot id: A0A075P5V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

589873:EP13 RS03760
gene id: 589873:EP13_RS03760
uniprot id: A0A075NTJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

589873:EP13 RS06590
gene id: 589873:EP13_RS06590
uniprot id: A0A075P527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

589873:EP13 RS16910
gene id: 589873:EP13_RS16910
uniprot id: A0A075PAE3
names: Similarity
messages: Belongs to the DEAD box helicase family.

589873:EP13 RS07460
gene id: 589873:EP13_RS07460
uniprot id: A0A075NYI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

589873:EP13 RS03150
gene id: 589873:EP13_RS03150
uniprot id: A0A075P3A2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

589873:EP13 RS18740
gene id: 589873:EP13_RS18740
uniprot id: A0A075PBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

589873:EP13 RS07070
gene id: 589873:EP13_RS07070
uniprot id: A0A075P5C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

589873:EP13 RS15085
gene id: 589873:EP13_RS15085
uniprot id: A0A075P296
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

589873:EP13 RS10000
gene id: 589873:EP13_RS10000
uniprot id: A0A075P216
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

589873:EP13 RS04030
gene id: 589873:EP13_RS04030
uniprot id: A0A075NTM2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS06875
gene id: 589873:EP13_RS06875
uniprot id: A0A075NY11
names: Similarity
messages: Belongs to the peptidase S51 family.

589873:EP13 RS13570
gene id: 589873:EP13_RS13570
uniprot id: A0A075P8N7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

589873:EP13 RS10245
gene id: 589873:EP13_RS10245
uniprot id: A0A075NZV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

589873:EP13 RS13045
gene id: 589873:EP13_RS13045
uniprot id: A0A075P177
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

589873:EP13 RS08740
gene id: 589873:EP13_RS08740
uniprot id: A0A075P1K9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

589873:EP13 RS00360
gene id: 589873:EP13_RS00360
uniprot id: A0A075NUR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

589873:EP13 RS11555
gene id: 589873:EP13_RS11555
uniprot id: A0A075P0L2
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS17835
gene id: 589873:EP13_RS17835
uniprot id: A0A075P462
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

589873:EP13 RS14985
gene id: 589873:EP13_RS14985
uniprot id: A0A075P4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

589873:EP13 RS01000
gene id: 589873:EP13_RS01000
uniprot id: A0A075NVH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS05315
gene id: 589873:EP13_RS05315
uniprot id: A0A075NU51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

589873:EP13 RS05860
gene id: 589873:EP13_RS05860
uniprot id: A0A075P0B6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

589873:EP13 RS03955
gene id: 589873:EP13_RS03955
uniprot id: A0A358DUS7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS07975
gene id: 589873:EP13_RS07975
uniprot id: A0A075NYL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

589873:EP13 RS14150
gene id: 589873:EP13_RS14150
uniprot id: A0A075P4C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

589873:EP13 RS15250
gene id: 589873:EP13_RS15250
uniprot id: A0A075NZB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS14165
gene id: 589873:EP13_RS14165
uniprot id: A0A075P238
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

589873:EP13 RS11600
gene id: 589873:EP13_RS11600
uniprot id: A0A075P0G0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

589873:EP13 RS14310
gene id: 589873:EP13_RS14310
uniprot id: A0A075P4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

589873:EP13 RS07575
gene id: 589873:EP13_RS07575
uniprot id: A0A075NYE2
names: Similarity
messages: Belongs to the UPF0145 family.

589873:EP13 RS00955
gene id: 589873:EP13_RS00955
uniprot id: A0A075NS91
names: Similarity
messages: Belongs to the thioesterase PaaI family.

589873:EP13 RS10910
gene id: 589873:EP13_RS10910
uniprot id: A0A075NWZ7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

589873:EP13 RS14800
gene id: 589873:EP13_RS14800
uniprot id: A0A075P4N6
names: Similarity
messages: Belongs to the AHA1 family.

589873:EP13 RS09050
gene id: 589873:EP13_RS09050
uniprot id: A0A075NW69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

589873:EP13 RS00785
gene id: 589873:EP13_RS00785
uniprot id: A0A075NV17
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS03570
gene id: 589873:EP13_RS03570
uniprot id: A0A075NWK3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

589873:EP13 RS09920
gene id: 589873:EP13_RS09920
uniprot id: A0A075NWK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

589873:EP13 RS16445
gene id: 589873:EP13_RS16445
uniprot id: A0A075P2X7
names: Similarity
messages: Belongs to the GbsR family.

589873:EP13 RS12675
gene id: 589873:EP13_RS12675
uniprot id: A0A075P102
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

589873:EP13 RS14330
gene id: 589873:EP13_RS14330
uniprot id: A0A075NYW4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

589873:EP13 RS08270
gene id: 589873:EP13_RS08270
uniprot id: A0A075NVP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

589873:EP13 RS02410
gene id: 589873:EP13_RS02410
uniprot id: A0A075NSV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

589873:EP13 RS06800
gene id: 589873:EP13_RS06800
uniprot id: A0A075P568
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

589873:EP13 RS08390
gene id: 589873:EP13_RS08390
uniprot id: A0A075P618
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

589873:EP13 RS08830
gene id: 589873:EP13_RS08830
uniprot id: A0A075NZ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

589873:EP13 RS16870
gene id: 589873:EP13_RS16870
uniprot id: A0A075P5X1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS11805
gene id: 589873:EP13_RS11805
uniprot id: A0A075P321
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

589873:EP13 RS02170
gene id: 589873:EP13_RS02170
uniprot id: A0A075NVT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

589873:EP13 RS08980
gene id: 589873:EP13_RS08980
uniprot id: A0A075P6B8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

589873:EP13 RS08030
gene id: 589873:EP13_RS08030
uniprot id: A0A075P5U5
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS05135
gene id: 589873:EP13_RS05135
uniprot id: A0A075P4D9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

589873:EP13 RS12060
gene id: 589873:EP13_RS12060
uniprot id: A0A075P7X9
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

589873:EP13 RS06475
gene id: 589873:EP13_RS06475
uniprot id: A0A075NUU1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

589873:EP13 RS07965
gene id: 589873:EP13_RS07965
uniprot id: A0A075NVI4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

589873:EP13 RS17560
gene id: 589873:EP13_RS17560
uniprot id: A0A075P414
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

589873:EP13 RS08355
gene id: 589873:EP13_RS08355
uniprot id: A0A075P1D8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

589873:EP13 RS13950
gene id: 589873:EP13_RS13950
uniprot id: A0A075P1V2
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

589873:EP13 RS05545
gene id: 589873:EP13_RS05545
uniprot id: A0A075NUA2
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

589873:EP13 RS08940
gene id: 589873:EP13_RS08940
uniprot id: A0A075NW53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

589873:EP13 RS18715
gene id: 589873:EP13_RS18715
uniprot id: A0A075PBA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

589873:EP13 RS09120
gene id: 589873:EP13_RS09120
uniprot id: A0A075P6E3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS12065
gene id: 589873:EP13_RS12065
uniprot id: A0A075P0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS18410
gene id: 589873:EP13_RS18410
uniprot id: A0A075P6M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

589873:EP13 RS14835
gene id: 589873:EP13_RS14835
uniprot id: A0A075P9D2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

589873:EP13 RS14540
gene id: 589873:EP13_RS14540
uniprot id: A0A075P4J4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

589873:EP13 RS12715
gene id: 589873:EP13_RS12715
uniprot id: A0A075NXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

589873:EP13 RS15945
gene id: 589873:EP13_RS15945
uniprot id: A0A075P9W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

589873:EP13 RS12150
gene id: 589873:EP13_RS12150
uniprot id: A0A075NXM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

589873:EP13 RS14975
gene id: 589873:EP13_RS14975
uniprot id: A0A075P2J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

589873:EP13 RS10150
gene id: 589873:EP13_RS10150
uniprot id: A0A075P236
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS14370
gene id: 589873:EP13_RS14370
uniprot id: A0A075P952
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS11700
gene id: 589873:EP13_RS11700
uniprot id: A0A075P2Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS16580
gene id: 589873:EP13_RS16580
uniprot id: A0A075P305
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

589873:EP13 RS08545
gene id: 589873:EP13_RS08545
uniprot id: A0A075NVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS03520
gene id: 589873:EP13_RS03520
uniprot id: A0A075NTH3
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

589873:EP13 RS06790
gene id: 589873:EP13_RS06790
uniprot id: A0A075P0S0
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS18295
gene id: 589873:EP13_RS18295
uniprot id: A0A075P4E7
names: Similarity
messages: Belongs to the SlyX family.

589873:EP13 RS17095
gene id: 589873:EP13_RS17095
uniprot id: A0A075PAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

589873:EP13 RS06040
gene id: 589873:EP13_RS06040
uniprot id: A0A075NY26
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

589873:EP13 RS14965
gene id: 589873:EP13_RS14965
uniprot id: A0A075P278
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

589873:EP13 RS16815
gene id: 589873:EP13_RS16815
uniprot id: A0A075P5W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

589873:EP13 RS07280
gene id: 589873:EP13_RS07280
uniprot id: A0A075P5F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

589873:EP13 RS09510
gene id: 589873:EP13_RS09510
uniprot id: A0A075NZI2
names: Similarity
messages: Belongs to the UPF0352 family.

589873:EP13 RS01890
gene id: 589873:EP13_RS01890
uniprot id: A0A075NVR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

589873:EP13 RS02970
gene id: 589873:EP13_RS02970
uniprot id: A0A075P337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

589873:EP13 RS18360
gene id: 589873:EP13_RS18360
uniprot id: A0A075P3Z9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

589873:EP13 RS04580
gene id: 589873:EP13_RS04580
uniprot id: A0A075P425
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS14395
gene id: 589873:EP13_RS14395
uniprot id: A0A075P957
names: Similarity
messages: Belongs to the UPF0246 family.

589873:EP13 RS18470
gene id: 589873:EP13_RS18470
uniprot id: A0A075PB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

589873:EP13 RS14155
gene id: 589873:EP13_RS14155
uniprot id: A0A075P1W8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS11685
gene id: 589873:EP13_RS11685
uniprot id: A0A075P7R8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS00140
gene id: 589873:EP13_RS00140
uniprot id: A0A075P1G4
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

589873:EP13 RS16345
gene id: 589873:EP13_RS16345
uniprot id: A0A075P5I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

589873:EP13 RS09335
gene id: 589873:EP13_RS09335
uniprot id: A0A075P1S1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

589873:EP13 RS10275
gene id: 589873:EP13_RS10275
uniprot id: A0A075NWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

589873:EP13 RS10470
gene id: 589873:EP13_RS10470
uniprot id: A0A075NZW6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS05480
gene id: 589873:EP13_RS05480
uniprot id: A0A075NXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

589873:EP13 RS09375
gene id: 589873:EP13_RS09375
uniprot id: A0A075NZG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS00605
gene id: 589873:EP13_RS00605
uniprot id: A0A075NUY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

589873:EP13 RS17780
gene id: 589873:EP13_RS17780
uniprot id: A0A075PAT9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS02820
gene id: 589873:EP13_RS02820
uniprot id: A0A075NW49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

589873:EP13 RS12395
gene id: 589873:EP13_RS12395
uniprot id: A0A075P817
names: Similarity
messages: Belongs to the P(II) protein family.

589873:EP13 RS00090
gene id: 589873:EP13_RS00090
uniprot id: A0A075NV70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

589873:EP13 RS01260
gene id: 589873:EP13_RS01260
uniprot id: A0A075NSE1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

589873:EP13 RS18190
gene id: 589873:EP13_RS18190
uniprot id: A0A075PB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS02210
gene id: 589873:EP13_RS02210
uniprot id: A0A075NVV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS06470
gene id: 589873:EP13_RS06470
uniprot id: A0A075NY73
names: Subcellular Location Annotation
messages: Cytoplasm

589873:EP13 RS09440
gene id: 589873:EP13_RS09440
uniprot id: A0A075P1T4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

589873:EP13 RS09445
gene id: 589873:EP13_RS09445
uniprot id: A0A075NZE7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS12205
gene id: 589873:EP13_RS12205
uniprot id: A0A075P370
names: Similarity
messages: Belongs to the CFA/CMAS family.

589873:EP13 RS08340
gene id: 589873:EP13_RS08340
uniprot id: A0A075P610
names: Similarity
messages: Belongs to the fabD family.

589873:EP13 RS03960
gene id: 589873:EP13_RS03960
uniprot id: A0A075NZB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

589873:EP13 RS11060
gene id: 589873:EP13_RS11060
uniprot id: A0A075P091
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS15075
gene id: 589873:EP13_RS15075
uniprot id: A0A075P4S5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

589873:EP13 RS01050
gene id: 589873:EP13_RS01050
uniprot id: A0A075NVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

589873:EP13 RS11205
gene id: 589873:EP13_RS11205
uniprot id: A0A075P070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

589873:EP13 RS11945
gene id: 589873:EP13_RS11945
uniprot id: A0A075P0M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS07555
gene id: 589873:EP13_RS07555
uniprot id: A0A075P5K1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

589873:EP13 RS06685
gene id: 589873:EP13_RS06685
uniprot id: A0A075P0Q0
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

589873:EP13 RS00145
gene id: 589873:EP13_RS00145
uniprot id: A0A075NV77
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS02090
gene id: 589873:EP13_RS02090
uniprot id: A0A075NYA6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

589873:EP13 RS15280
gene id: 589873:EP13_RS15280
uniprot id: A0A075NZC2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

589873:EP13 RS04660
gene id: 589873:EP13_RS04660
uniprot id: A0A075P438
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

589873:EP13 RS13975
gene id: 589873:EP13_RS13975
uniprot id: A0A075P469
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

589873:EP13 RS02915
gene id: 589873:EP13_RS02915
uniprot id: A0A075NW77
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

589873:EP13 RS10890
gene id: 589873:EP13_RS10890
uniprot id: A0A075P7A8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS04000
gene id: 589873:EP13_RS04000
uniprot id: A0A075NWV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

589873:EP13 RS00650
gene id: 589873:EP13_RS00650
uniprot id: A0A075NXF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

589873:EP13 RS13210
gene id: 589873:EP13_RS13210
uniprot id: A0A075P8H5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS08970
gene id: 589873:EP13_RS08970
uniprot id: A0A075P1M8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS16705
gene id: 589873:EP13_RS16705
uniprot id: A0A075P5Q8
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

589873:EP13 RS14110
gene id: 589873:EP13_RS14110
uniprot id: A0A075P911
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

589873:EP13 RS17175
gene id: 589873:EP13_RS17175
uniprot id: A0A075PAI4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

589873:EP13 RS14845
gene id: 589873:EP13_RS14845
uniprot id: A0A075NZ34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

589873:EP13 RS16780
gene id: 589873:EP13_RS16780
uniprot id: A0A075P082
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS08430
gene id: 589873:EP13_RS08430
uniprot id: A0A075P1F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS05100
gene id: 589873:EP13_RS05100
uniprot id: A0A075NZV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

589873:EP13 RS04715
gene id: 589873:EP13_RS04715
uniprot id: A0A075NX89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

589873:EP13 RS03390
gene id: 589873:EP13_RS03390
uniprot id: A0A075NZ23
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

589873:EP13 RS03370
gene id: 589873:EP13_RS03370
uniprot id: A0A075NWJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

589873:EP13 RS08785
gene id: 589873:EP13_RS08785
uniprot id: A0A075NW26
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

589873:EP13 RS07025
gene id: 589873:EP13_RS07025
uniprot id: A0A075NYC3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

589873:EP13 RS09295
gene id: 589873:EP13_RS09295
uniprot id: A0A075P6H1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

589873:EP13 RS07255
gene id: 589873:EP13_RS07255
uniprot id: A0A075P5F3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS09515
gene id: 589873:EP13_RS09515
uniprot id: A0A075NWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

589873:EP13 RS10915
gene id: 589873:EP13_RS10915
uniprot id: A0A075P2I6
names: Similarity
messages: Belongs to the MoaD family.

589873:EP13 RS17535
gene id: 589873:EP13_RS17535
uniprot id: A0A075P410
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

589873:EP13 RS03800
gene id: 589873:EP13_RS03800
uniprot id: A0A075P3M1
names: Similarity
messages: Belongs to the BolA/IbaG family.

589873:EP13 RS09685
gene id: 589873:EP13_RS09685
uniprot id: A0A075P1X0
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

589873:EP13 RS11965
gene id: 589873:EP13_RS11965
uniprot id: A0A075P347
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

589873:EP13 RS14620
gene id: 589873:EP13_RS14620
uniprot id: A0A075P227
names: Similarity
messages: Belongs to the glutamate synthase family.

589873:EP13 RS02285
gene id: 589873:EP13_RS02285
uniprot id: A0A075NVW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

589873:EP13 RS03995
gene id: 589873:EP13_RS03995
uniprot id: A0A075P3Q2
names: Subcellular Location Annotation
messages: Cytoplasm

589873:EP13 RS16300
gene id: 589873:EP13_RS16300
uniprot id: A0A075P2V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

589873:EP13 RS07635
gene id: 589873:EP13_RS07635
uniprot id: A0A075P5L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS14010
gene id: 589873:EP13_RS14010
uniprot id: A0A075P8U9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

589873:EP13 RS10530
gene id: 589873:EP13_RS10530
uniprot id: A0A075P009
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

589873:EP13 RS04430
gene id: 589873:EP13_RS04430
uniprot id: A0A075P3Z5
names: Similarity
messages: Belongs to the type III secretion exporter family.

589873:EP13 RS12165
gene id: 589873:EP13_RS12165
uniprot id: A0A075P7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

589873:EP13 RS18160
gene id: 589873:EP13_RS18160
uniprot id: A0A075P3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS00010
gene id: 589873:EP13_RS00010
uniprot id: A0A075NRP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

589873:EP13 RS00245
gene id: 589873:EP13_RS00245
uniprot id: A0A075NV88
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS12285
gene id: 589873:EP13_RS12285
uniprot id: A0A075P0T9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

589873:EP13 RS13935
gene id: 589873:EP13_RS13935
uniprot id: A0A075P459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS05055
gene id: 589873:EP13_RS05055
uniprot id: A0A075P4C0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

589873:EP13 RS05255
gene id: 589873:EP13_RS05255
uniprot id: A0A075NZZ2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

589873:EP13 RS00365
gene id: 589873:EP13_RS00365
uniprot id: A0A075P1K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

589873:EP13 RS06825
gene id: 589873:EP13_RS06825
uniprot id: A0A075P574
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS08620
gene id: 589873:EP13_RS08620
uniprot id: A0A075NVZ8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

589873:EP13 RS05445
gene id: 589873:EP13_RS05445
uniprot id: A0A075P026
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

589873:EP13 RS05405
gene id: 589873:EP13_RS05405
uniprot id: A0A075P4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS03365
gene id: 589873:EP13_RS03365
uniprot id: A0A075NZ20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

589873:EP13 RS10300
gene id: 589873:EP13_RS10300
uniprot id: A0A075NWP7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

589873:EP13 RS03710
gene id: 589873:EP13_RS03710
uniprot id: A0A075NTJ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS13715
gene id: 589873:EP13_RS13715
uniprot id: A0A075NYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS04955
gene id: 589873:EP13_RS04955
uniprot id: A0A075NTY2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

589873:EP13 RS10375
gene id: 589873:EP13_RS10375
uniprot id: A0A075NZY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

589873:EP13 RS06185
gene id: 589873:EP13_RS06185
uniprot id: A0A075NUQ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS05425
gene id: 589873:EP13_RS05425
uniprot id: A0A075NXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

589873:EP13 RS09330
gene id: 589873:EP13_RS09330
uniprot id: A0A075NWB5
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

589873:EP13 RS00945
gene id: 589873:EP13_RS00945
uniprot id: A0A075P1Y8
names: Similarity
messages: Belongs to the GST superfamily.

589873:EP13 RS08375
gene id: 589873:EP13_RS08375
uniprot id: A0A075NVR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

589873:EP13 RS05930
gene id: 589873:EP13_RS05930
uniprot id: A0A075NY09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

589873:EP13 RS12680
gene id: 589873:EP13_RS12680
uniprot id: A0A075P873
names: Similarity
messages: Belongs to the SufE family.

589873:EP13 RS11695
gene id: 589873:EP13_RS11695
uniprot id: A0A075NXE4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS11710
gene id: 589873:EP13_RS11710
uniprot id: A0A075P7S1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

589873:EP13 RS14935
gene id: 589873:EP13_RS14935
uniprot id: A0A075P4Q6
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

589873:EP13 RS08855
gene id: 589873:EP13_RS08855
uniprot id: A0A075NZ63
names: Similarity
messages: Belongs to the peptidase S49 family.

589873:EP13 RS15105
gene id: 589873:EP13_RS15105
uniprot id: A0A075P4S9
names: Similarity
messages: Belongs to the peptidase M16 family.

589873:EP13 RS00080
gene id: 589873:EP13_RS00080
uniprot id: A0A075P1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

589873:EP13 RS04735
gene id: 589873:EP13_RS04735
uniprot id: A0A075P457
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

589873:EP13 RS10295
gene id: 589873:EP13_RS10295
uniprot id: A0A075NZW8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

589873:EP13 RS16625
gene id: 589873:EP13_RS16625
uniprot id: A0A075P5P1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS00705
gene id: 589873:EP13_RS00705
uniprot id: A0A075NV06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

589873:EP13 RS15505
gene id: 589873:EP13_RS15505
uniprot id: A0A075P2H1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

589873:EP13 RS02140
gene id: 589873:EP13_RS02140
uniprot id: A0A075NYB7
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

589873:EP13 RS11845
gene id: 589873:EP13_RS11845
uniprot id: A0A075P7U2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

589873:EP13 RS09905
gene id: 589873:EP13_RS09905
uniprot id: A0A075NZN0
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

589873:EP13 RS03595
gene id: 589873:EP13_RS03595
uniprot id: A0A075NWK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

589873:EP13 RS10540
gene id: 589873:EP13_RS10540
uniprot id: A0A075P2A0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

589873:EP13 RS15745
gene id: 589873:EP13_RS15745
uniprot id: A0A075P553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

589873:EP13 RS04460
gene id: 589873:EP13_RS04460
uniprot id: A0A075NX51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

589873:EP13 RS18265
gene id: 589873:EP13_RS18265
uniprot id: A0A075PB21
names: Similarity
messages: Belongs to the UPF0270 family.

589873:EP13 RS09910
gene id: 589873:EP13_RS09910
uniprot id: A0A075P6V2
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

589873:EP13 RS18070
gene id: 589873:EP13_RS18070
uniprot id: A0A075P0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

589873:EP13 RS04365
gene id: 589873:EP13_RS04365
uniprot id: A0A075NTR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

589873:EP13 RS01265
gene id: 589873:EP13_RS01265
uniprot id: A0A075NXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

589873:EP13 RS02925
gene id: 589873:EP13_RS02925
uniprot id: A0A075NW75
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS04695
gene id: 589873:EP13_RS04695
uniprot id: A0A075NTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

589873:EP13 RS03165
gene id: 589873:EP13_RS03165
uniprot id: A0A075NYZ2
names: Similarity
messages: Belongs to the BolA/IbaG family.

589873:EP13 RS03740
gene id: 589873:EP13_RS03740
uniprot id: A0A075NZ82
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

589873:EP13 RS05950
gene id: 589873:EP13_RS05950
uniprot id: A0A075P4R9
names: Similarity
messages: Belongs to the UPF0229 family.

589873:EP13 RS06780
gene id: 589873:EP13_RS06780
uniprot id: A0A075NYA1
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS01080
gene id: 589873:EP13_RS01080
uniprot id: A0A075NSB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

589873:EP13 RS14125
gene id: 589873:EP13_RS14125
uniprot id: A0A075P4B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

589873:EP13 RS07020
gene id: 589873:EP13_RS07020
uniprot id: A0A075P5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

589873:EP13 RS00625
gene id: 589873:EP13_RS00625
uniprot id: A0A075NXF2
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

589873:EP13 RS07150
gene id: 589873:EP13_RS07150
uniprot id: A0A075NYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

589873:EP13 RS10835
gene id: 589873:EP13_RS10835
uniprot id: A0A075P799
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

589873:EP13 RS01200
gene id: 589873:EP13_RS01200
uniprot id: A0A075P241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

589873:EP13 RS08925
gene id: 589873:EP13_RS08925
uniprot id: A0A075NZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

589873:EP13 RS15115
gene id: 589873:EP13_RS15115
uniprot id: A0A075P9I2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS01665
gene id: 589873:EP13_RS01665
uniprot id: A0A075NVJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS01765
gene id: 589873:EP13_RS01765
uniprot id: A0A075NSK7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

589873:EP13 RS16675
gene id: 589873:EP13_RS16675
uniprot id: A0A075P5Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS13835
gene id: 589873:EP13_RS13835
uniprot id: A0A075P1T1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS00805
gene id: 589873:EP13_RS00805
uniprot id: A0A075NXJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

589873:EP13 RS14580
gene id: 589873:EP13_RS14580
uniprot id: A0A075P2C1
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

589873:EP13 RS01985
gene id: 589873:EP13_RS01985
uniprot id: A0A075P2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

589873:EP13 RS17990
gene id: 589873:EP13_RS17990
uniprot id: A0A075P0S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

589873:EP13 RS03350
gene id: 589873:EP13_RS03350
uniprot id: A0A075P3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

589873:EP13 RS17490
gene id: 589873:EP13_RS17490
uniprot id: A0A075PAN6
names: Similarity
messages: Belongs to the TPP enzyme family.

589873:EP13 RS01280
gene id: 589873:EP13_RS01280
uniprot id: A0A075NVK2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

589873:EP13 RS04060
gene id: 589873:EP13_RS04060
uniprot id: A0A075NZC7
names: Similarity
messages: Belongs to the IMPACT family.

589873:EP13 RS16655
gene id: 589873:EP13_RS16655
uniprot id: A0A075P323
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

589873:EP13 RS06730
gene id: 589873:EP13_RS06730
uniprot id: A0A075NUX6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS17125
gene id: 589873:EP13_RS17125
uniprot id: A0A075P3U4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS09690
gene id: 589873:EP13_RS09690
uniprot id: A0A075NZJ2
names: Similarity
messages: Belongs to the peptidase S8 family.

589873:EP13 RS18445
gene id: 589873:EP13_RS18445
uniprot id: A0A075PB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS14980
gene id: 589873:EP13_RS14980
uniprot id: A0A075NZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

589873:EP13 RS02450
gene id: 589873:EP13_RS02450
uniprot id: A0A075NYH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

589873:EP13 RS01495
gene id: 589873:EP13_RS01495
uniprot id: A0A075NVM6
names: Similarity
messages: Belongs to the peptidase A31 family.

589873:EP13 RS16455
gene id: 589873:EP13_RS16455
uniprot id: A0A075P3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

589873:EP13 RS08680
gene id: 589873:EP13_RS08680
uniprot id: A0A075NW07
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS08920
gene id: 589873:EP13_RS08920
uniprot id: A0A075P1M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

589873:EP13 RS07595
gene id: 589873:EP13_RS07595
uniprot id: A0A075P141
names: Similarity
messages: Belongs to the ArsC family.

589873:EP13 RS10215
gene id: 589873:EP13_RS10215
uniprot id: A0A075P6Y5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

589873:EP13 RS10225
gene id: 589873:EP13_RS10225
uniprot id: A0A075NWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

589873:EP13 RS11975
gene id: 589873:EP13_RS11975
uniprot id: A0A075P7W8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

589873:EP13 RS03750
gene id: 589873:EP13_RS03750
uniprot id: A0A075P3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

589873:EP13 RS04895
gene id: 589873:EP13_RS04895
uniprot id: A0A075P492
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

589873:EP13 RS06715
gene id: 589873:EP13_RS06715
uniprot id: A0A075NXY7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS02585
gene id: 589873:EP13_RS02585
uniprot id: A0A075NYK4
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

589873:EP13 RS09365
gene id: 589873:EP13_RS09365
uniprot id: A0A075NZD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS12545
gene id: 589873:EP13_RS12545
uniprot id: A0A075P0Y9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

589873:EP13 RS18705
gene id: 589873:EP13_RS18705
uniprot id: A0A075P6S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

589873:EP13 RS03685
gene id: 589873:EP13_RS03685
uniprot id: A0A075NTI8
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

589873:EP13 RS05925
gene id: 589873:EP13_RS05925
uniprot id: A0A075P4R3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

589873:EP13 RS09705
gene id: 589873:EP13_RS09705
uniprot id: A0A075NWG3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

589873:EP13 RS12220
gene id: 589873:EP13_RS12220
uniprot id: A0A075P0W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

589873:EP13 RS16380
gene id: 589873:EP13_RS16380
uniprot id: A0A075P2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS14055
gene id: 589873:EP13_RS14055
uniprot id: A0A075P1U0
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS00600
gene id: 589873:EP13_RS00600
uniprot id: A0A075NXE6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

589873:EP13 RS01955
gene id: 589873:EP13_RS01955
uniprot id: A0A075NVP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

589873:EP13 RS15310
gene id: 589873:EP13_RS15310
uniprot id: A0A075P4X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS10685
gene id: 589873:EP13_RS10685
uniprot id: A0A075NWW1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

589873:EP13 RS00880
gene id: 589873:EP13_RS00880
uniprot id: A0A075NXK5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS04530
gene id: 589873:EP13_RS04530
uniprot id: A0A075P416
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS16270
gene id: 589873:EP13_RS16270
uniprot id: A0A075P5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

589873:EP13 RS16720
gene id: 589873:EP13_RS16720
uniprot id: A0A075P3K1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

589873:EP13 RS19180
gene id: 589873:EP13_RS19180
uniprot id: A0A350P747
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS11820
gene id: 589873:EP13_RS11820
uniprot id: A0A075P0Q6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS13100
gene id: 589873:EP13_RS13100
uniprot id: A0A075P8F9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

589873:EP13 RS11370
gene id: 589873:EP13_RS11370
uniprot id: A0A075P0C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS13345
gene id: 589873:EP13_RS13345
uniprot id: A0A075P3T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

589873:EP13 RS13110
gene id: 589873:EP13_RS13110
uniprot id: A0A075NY38
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

589873:EP13 RS15625
gene id: 589873:EP13_RS15625
uniprot id: A0A075P2I9
names: Similarity
messages: Belongs to the PspA/IM30 family.

589873:EP13 RS16685
gene id: 589873:EP13_RS16685
uniprot id: A0A075PA91
names: Similarity
messages: Belongs to the peptidase M17 family.

589873:EP13 RS16715
gene id: 589873:EP13_RS16715
uniprot id: A0A075PA96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

589873:EP13 RS12755
gene id: 589873:EP13_RS12755
uniprot id: A0A075P890
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

589873:EP13 RS06355
gene id: 589873:EP13_RS06355
uniprot id: A0A075NXV2
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS06140
gene id: 589873:EP13_RS06140
uniprot id: A0A075P4U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

589873:EP13 RS16305
gene id: 589873:EP13_RS16305
uniprot id: A0A075PA27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

589873:EP13 RS00505
gene id: 589873:EP13_RS00505
uniprot id: A0A075P1Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

589873:EP13 RS18710
gene id: 589873:EP13_RS18710
uniprot id: A0A075P472
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

589873:EP13 RS02900
gene id: 589873:EP13_RS02900
uniprot id: A0A075NW71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

589873:EP13 RS10305
gene id: 589873:EP13_RS10305
uniprot id: A0A075P263
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

589873:EP13 RS16330
gene id: 589873:EP13_RS16330
uniprot id: A0A075PA31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

589873:EP13 RS03630
gene id: 589873:EP13_RS03630
uniprot id: A0A075NWL3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

589873:EP13 RS09975
gene id: 589873:EP13_RS09975
uniprot id: A0A075P213
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS07275
gene id: 589873:EP13_RS07275
uniprot id: A0A075NY85
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

589873:EP13 RS10285
gene id: 589873:EP13_RS10285
uniprot id: A0A075NZU0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS17230
gene id: 589873:EP13_RS17230
uniprot id: A0A075P3W4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

589873:EP13 RS10460
gene id: 589873:EP13_RS10460
uniprot id: A0A075NWS0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS09720
gene id: 589873:EP13_RS09720
uniprot id: A0A075P6S2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

589873:EP13 RS17610
gene id: 589873:EP13_RS17610
uniprot id: A0A075P3L7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

589873:EP13 RS01120
gene id: 589873:EP13_RS01120
uniprot id: A0A075P223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

589873:EP13 RS04445
gene id: 589873:EP13_RS04445
uniprot id: A0A075NZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

589873:EP13 RS03490
gene id: 589873:EP13_RS03490
uniprot id: A0A075NZ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

589873:EP13 RS02985
gene id: 589873:EP13_RS02985
uniprot id: A0A075NYS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS14280
gene id: 589873:EP13_RS14280
uniprot id: A0A075NYV7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

589873:EP13 RS12710
gene id: 589873:EP13_RS12710
uniprot id: A0A075P168
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

589873:EP13 RS08595
gene id: 589873:EP13_RS08595
uniprot id: A0A075P1K2
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

589873:EP13 RS16320
gene id: 589873:EP13_RS16320
uniprot id: A0A075P5I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

589873:EP13 RS07540
gene id: 589873:EP13_RS07540
uniprot id: A0A075NVA1
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS02825
gene id: 589873:EP13_RS02825
uniprot id: A0A075NT16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS12815
gene id: 589873:EP13_RS12815
uniprot id: A0A075NXZ5
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS14570
gene id: 589873:EP13_RS14570
uniprot id: A0A075P220
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

589873:EP13 RS09750
gene id: 589873:EP13_RS09750
uniprot id: A0A075P6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.

589873:EP13 RS14815
gene id: 589873:EP13_RS14815
uniprot id: A0A075P2G2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

589873:EP13 RS07430
gene id: 589873:EP13_RS07430
uniprot id: A0A075NYI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

589873:EP13 RS04500
gene id: 589873:EP13_RS04500
uniprot id: A0A075NX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

589873:EP13 RS15990
gene id: 589873:EP13_RS15990
uniprot id: A0A075P2Q2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS10445
gene id: 589873:EP13_RS10445
uniprot id: A0A075NZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

589873:EP13 RS05085
gene id: 589873:EP13_RS05085
uniprot id: A0A075P4C6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

589873:EP13 RS14030
gene id: 589873:EP13_RS14030
uniprot id: A0A075P1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

589873:EP13 RS01895
gene id: 589873:EP13_RS01895
uniprot id: A0A075NSM4
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

589873:EP13 RS17825
gene id: 589873:EP13_RS17825
uniprot id: A0A075P3Q1
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

589873:EP13 RS00340
gene id: 589873:EP13_RS00340
uniprot id: A0A075P1J7
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS08705
gene id: 589873:EP13_RS08705
uniprot id: A0A075NZ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

589873:EP13 RS00015
gene id: 589873:EP13_RS00015
uniprot id: A0A075NX03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

589873:EP13 RS08330
gene id: 589873:EP13_RS08330
uniprot id: A0A075P1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

589873:EP13 RS01500
gene id: 589873:EP13_RS01500
uniprot id: A0A075NSH0
names: Similarity
messages: Belongs to the HupH/HyaF family.

589873:EP13 RS09845
gene id: 589873:EP13_RS09845
uniprot id: A0A075NZM0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

589873:EP13 RS02800
gene id: 589873:EP13_RS02800
uniprot id: A0A075NT12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

589873:EP13 RS15940
gene id: 589873:EP13_RS15940
uniprot id: A0A075P2P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

589873:EP13 RS04850
gene id: 589873:EP13_RS04850
uniprot id: A0A075NXB0
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

589873:EP13 RS14525
gene id: 589873:EP13_RS14525
uniprot id: A0A075P979
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

589873:EP13 RS17970
gene id: 589873:EP13_RS17970
uniprot id: A0A075P6D4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

589873:EP13 RS07660
gene id: 589873:EP13_RS07660
uniprot id: A0A075P5M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

589873:EP13 RS08105
gene id: 589873:EP13_RS08105
uniprot id: A0A075P5W2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

589873:EP13 RS08035
gene id: 589873:EP13_RS08035
uniprot id: A0A075NYR1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

589873:EP13 RS11610
gene id: 589873:EP13_RS11610
uniprot id: A0A075P0L9
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

589873:EP13 RS14675
gene id: 589873:EP13_RS14675
uniprot id: A0A075P2D7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

589873:EP13 RS11785
gene id: 589873:EP13_RS11785
uniprot id: A0A075P0J1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

589873:EP13 RS05185
gene id: 589873:EP13_RS05185
uniprot id: A0A075P4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

589873:EP13 RS08415
gene id: 589873:EP13_RS08415
uniprot id: A0A075P622
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS06235
gene id: 589873:EP13_RS06235
uniprot id: A0A075NUQ9
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS00290
gene id: 589873:EP13_RS00290
uniprot id: A0A075P1J0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

589873:EP13 RS12760
gene id: 589873:EP13_RS12760
uniprot id: A0A075P180
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS04155
gene id: 589873:EP13_RS04155
uniprot id: A0A075P3U5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

589873:EP13 RS15980
gene id: 589873:EP13_RS15980
uniprot id: A0A075NZR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS06255
gene id: 589873:EP13_RS06255
uniprot id: A0A075NY54
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

589873:EP13 RS08250
gene id: 589873:EP13_RS08250
uniprot id: A0A075P1B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

589873:EP13 RS12325
gene id: 589873:EP13_RS12325
uniprot id: A0A075NXQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS18075
gene id: 589873:EP13_RS18075
uniprot id: A0A075P6F1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

589873:EP13 RS12155
gene id: 589873:EP13_RS12155
uniprot id: A0A075P364
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

589873:EP13 RS02250
gene id: 589873:EP13_RS02250
uniprot id: A0A075NVV1
names: Similarity
messages: Belongs to the catalase family.

589873:EP13 RS14645
gene id: 589873:EP13_RS14645
uniprot id: A0A075P4L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS18270
gene id: 589873:EP13_RS18270
uniprot id: A0A075P4E1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

589873:EP13 RS15935
gene id: 589873:EP13_RS15935
uniprot id: A0A075P5B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

589873:EP13 RS03765
gene id: 589873:EP13_RS03765
uniprot id: A0A075NZ86
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

589873:EP13 RS12440
gene id: 589873:EP13_RS12440
uniprot id: A0A075P3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

589873:EP13 RS15090
gene id: 589873:EP13_RS15090
uniprot id: A0A075P9H7
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

589873:EP13 RS07125
gene id: 589873:EP13_RS07125
uniprot id: A0A075NYD3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

589873:EP13 RS12400
gene id: 589873:EP13_RS12400
uniprot id: A0A075P103
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

589873:EP13 RS00835
gene id: 589873:EP13_RS00835
uniprot id: A0A075NV26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

589873:EP13 RS12330
gene id: 589873:EP13_RS12330
uniprot id: A0A075P389
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

589873:EP13 RS17060
gene id: 589873:EP13_RS17060
uniprot id: A0A075P600
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

589873:EP13 RS05250
gene id: 589873:EP13_RS05250
uniprot id: A0A075NU39
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS03585
gene id: 589873:EP13_RS03585
uniprot id: A0A075NWM9
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

589873:EP13 RS04395
gene id: 589873:EP13_RS04395
uniprot id: A0A075NZH2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS14875
gene id: 589873:EP13_RS14875
uniprot id: A0A075NZ42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

589873:EP13 RS16710
gene id: 589873:EP13_RS16710
uniprot id: A0A075P333
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

589873:EP13 RS18600
gene id: 589873:EP13_RS18600
uniprot id: A0A075P6Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

589873:EP13 RS14535
gene id: 589873:EP13_RS14535
uniprot id: A0A075NYZ1
names: Similarity
messages: Belongs to the UPF0102 family.

589873:EP13 RS11910
gene id: 589873:EP13_RS11910
uniprot id: A0A075NXI1
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

589873:EP13 RS06010
gene id: 589873:EP13_RS06010
uniprot id: A0A075NY21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

589873:EP13 RS01165
gene id: 589873:EP13_RS01165
uniprot id: A0A075NVA0
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

589873:EP13 RS03745
gene id: 589873:EP13_RS03745
uniprot id: A0A075NWQ2
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

589873:EP13 RS07260
gene id: 589873:EP13_RS07260
uniprot id: A0A075NYF3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

589873:EP13 RS01630
gene id: 589873:EP13_RS01630
uniprot id: A0A075NSJ1
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS06535
gene id: 589873:EP13_RS06535
uniprot id: A0A075NXX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS14585
gene id: 589873:EP13_RS14585
uniprot id: A0A075NYZ5
names: Similarity
messages: Belongs to the PrpF family.

589873:EP13 RS08475
gene id: 589873:EP13_RS08475
uniprot id: A0A075P629
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

589873:EP13 RS16830
gene id: 589873:EP13_RS16830
uniprot id: A0A075P3P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

589873:EP13 RS04360
gene id: 589873:EP13_RS04360
uniprot id: A0A075NX30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

589873:EP13 RS11780
gene id: 589873:EP13_RS11780
uniprot id: A0A075P316
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

589873:EP13 RS08065
gene id: 589873:EP13_RS08065
uniprot id: A0A075NVK9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

589873:EP13 RS10605
gene id: 589873:EP13_RS10605
uniprot id: A0A075P023
names: Similarity
messages: Belongs to the UPF0178 family.

589873:EP13 RS15195
gene id: 589873:EP13_RS15195
uniprot id: A0A075P2P5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS12480
gene id: 589873:EP13_RS12480
uniprot id: A0A075P121
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

589873:EP13 RS08895
gene id: 589873:EP13_RS08895
uniprot id: A0A075P1M2
names: Similarity
messages: Belongs to the UPF0250 family.

589873:EP13 RS01990
gene id: 589873:EP13_RS01990
uniprot id: A0A075NVT0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

589873:EP13 RS01510
gene id: 589873:EP13_RS01510
uniprot id: A0A075NVG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

589873:EP13 RS18180
gene id: 589873:EP13_RS18180
uniprot id: A0A349TPS7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS05965
gene id: 589873:EP13_RS05965
uniprot id: A0A075P0D5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

589873:EP13 RS16035
gene id: 589873:EP13_RS16035
uniprot id: A0A075P5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

589873:EP13 RS13380
gene id: 589873:EP13_RS13380
uniprot id: A0A075NY88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS02300
gene id: 589873:EP13_RS02300
uniprot id: A0A075NVW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

589873:EP13 RS16540
gene id: 589873:EP13_RS16540
uniprot id: A0A075P020
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS02850
gene id: 589873:EP13_RS02850
uniprot id: A0A358E355
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS04670
gene id: 589873:EP13_RS04670
uniprot id: A0A075NTV3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS06150
gene id: 589873:EP13_RS06150
uniprot id: A0A075NUP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

589873:EP13 RS17905
gene id: 589873:EP13_RS17905
uniprot id: A0A075P0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS12245
gene id: 589873:EP13_RS12245
uniprot id: A0A075P0X1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

589873:EP13 RS08095
gene id: 589873:EP13_RS08095
uniprot id: A0A075P198
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

589873:EP13 RS03815
gene id: 589873:EP13_RS03815
uniprot id: A0A358DX91
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS05390
gene id: 589873:EP13_RS05390
uniprot id: A0A075NU67
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

589873:EP13 RS03045
gene id: 589873:EP13_RS03045
uniprot id: A0A075NWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

589873:EP13 RS00335
gene id: 589873:EP13_RS00335
uniprot id: A0A075NUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

589873:EP13 RS03005
gene id: 589873:EP13_RS03005
uniprot id: A0A075NW85
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS14420
gene id: 589873:EP13_RS14420
uniprot id: A0A075P960
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

589873:EP13 RS01605
gene id: 589873:EP13_RS01605
uniprot id: A0A075NSI6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

589873:EP13 RS15270
gene id: 589873:EP13_RS15270
uniprot id: A0A075P9L1
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

589873:EP13 RS00005
gene id: 589873:EP13_RS00005
uniprot id: A0A075NV59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

589873:EP13 RS02355
gene id: 589873:EP13_RS02355
uniprot id: A0A075NYG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

589873:EP13 RS04455
gene id: 589873:EP13_RS04455
uniprot id: A0A075P401
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

589873:EP13 RS06570
gene id: 589873:EP13_RS06570
uniprot id: A0A075NY84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

589873:EP13 RS00895
gene id: 589873:EP13_RS00895
uniprot id: A0A075NVG2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

589873:EP13 RS16205
gene id: 589873:EP13_RS16205
uniprot id: A0A075NZW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

589873:EP13 RS00590
gene id: 589873:EP13_RS00590
uniprot id: A0A075NVD5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

589873:EP13 RS05235
gene id: 589873:EP13_RS05235
uniprot id: A0A075NXB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

589873:EP13 RS06670
gene id: 589873:EP13_RS06670
uniprot id: A0A075NY92
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS09830
gene id: 589873:EP13_RS09830
uniprot id: A0A075NZN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

589873:EP13 RS02460
gene id: 589873:EP13_RS02460
uniprot id: A0A075P2T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

589873:EP13 RS01945
gene id: 589873:EP13_RS01945
uniprot id: A0A075NSN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

589873:EP13 RS11185
gene id: 589873:EP13_RS11185
uniprot id: A0A075P7H6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

589873:EP13 RS12465
gene id: 589873:EP13_RS12465
uniprot id: A0A075P3B5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

589873:EP13 RS06880
gene id: 589873:EP13_RS06880
uniprot id: A0A075P584
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

589873:EP13 RS13870
gene id: 589873:EP13_RS13870
uniprot id: A0A075NYJ6
names: Similarity
messages: Belongs to the TPP enzyme family.

589873:EP13 RS17415
gene id: 589873:EP13_RS17415
uniprot id: A0A075P0H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

589873:EP13 RS12270
gene id: 589873:EP13_RS12270
uniprot id: A0A075P0X7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

589873:EP13 RS11535
gene id: 589873:EP13_RS11535
uniprot id: A0A075P2X5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

589873:EP13 RS10620
gene id: 589873:EP13_RS10620
uniprot id: A0A075NZZ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS05905
gene id: 589873:EP13_RS05905
uniprot id: A0A075NY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

589873:EP13 RS14130
gene id: 589873:EP13_RS14130
uniprot id: A0A075P1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

589873:EP13 RS11605
gene id: 589873:EP13_RS11605
uniprot id: A0A075P7Q7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS16470
gene id: 589873:EP13_RS16470
uniprot id: A0A075P5K5
names: Subcellular Location Annotation
messages: Cytoplasm

589873:EP13 RS06560
gene id: 589873:EP13_RS06560
uniprot id: A0A075NXX3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

589873:EP13 RS11955
gene id: 589873:EP13_RS11955
uniprot id: A0A075P0S3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

589873:EP13 RS14230
gene id: 589873:EP13_RS14230
uniprot id: A0A075NYU9
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

589873:EP13 RS12230
gene id: 589873:EP13_RS12230
uniprot id: A0A075P373
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

589873:EP13 RS18420
gene id: 589873:EP13_RS18420
uniprot id: A0A075PB47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS15560
gene id: 589873:EP13_RS15560
uniprot id: A0A075P2V4
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS05900
gene id: 589873:EP13_RS05900
uniprot id: A0A075P4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

589873:EP13 RS08460
gene id: 589873:EP13_RS08460
uniprot id: A0A075NVT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

589873:EP13 RS09105
gene id: 589873:EP13_RS09105
uniprot id: A0A075NW78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS12735
gene id: 589873:EP13_RS12735
uniprot id: A0A075P175
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

589873:EP13 RS08825
gene id: 589873:EP13_RS08825
uniprot id: A0A075P691
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

589873:EP13 RS13295
gene id: 589873:EP13_RS13295
uniprot id: A0A075P1C0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS02240
gene id: 589873:EP13_RS02240
uniprot id: A0A075NST0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

589873:EP13 RS08485
gene id: 589873:EP13_RS08485
uniprot id: A0A075NVU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

589873:EP13 RS15470
gene id: 589873:EP13_RS15470
uniprot id: A0A075NZG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS04235
gene id: 589873:EP13_RS04235
uniprot id: A0A075NWX8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

589873:EP13 RS01115
gene id: 589873:EP13_RS01115
uniprot id: A0A075NV91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS01475
gene id: 589873:EP13_RS01475
uniprot id: A0A075NSG7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS16600
gene id: 589873:EP13_RS16600
uniprot id: A0A075P5N3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

589873:EP13 RS02430
gene id: 589873:EP13_RS02430
uniprot id: A0A075NVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS10995
gene id: 589873:EP13_RS10995
uniprot id: A0A075P2K1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

589873:EP13 RS03715
gene id: 589873:EP13_RS03715
uniprot id: A0A075NZ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

589873:EP13 RS10170
gene id: 589873:EP13_RS10170
uniprot id: A0A075NZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

589873:EP13 RS03310
gene id: 589873:EP13_RS03310
uniprot id: A0A075NTE6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS08910
gene id: 589873:EP13_RS08910
uniprot id: A0A075NZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

589873:EP13 RS02510
gene id: 589873:EP13_RS02510
uniprot id: A0A075P2U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

589873:EP13 RS16890
gene id: 589873:EP13_RS16890
uniprot id: A0A075P3Q3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

589873:EP13 RS10450
gene id: 589873:EP13_RS10450
uniprot id: A0A075P716
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

589873:EP13 RS01520
gene id: 589873:EP13_RS01520
uniprot id: A0A075NVN0
names: Similarity
messages: Belongs to the HupF/HypC family.

589873:EP13 RS06370
gene id: 589873:EP13_RS06370
uniprot id: A0A075NUS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

589873:EP13 RS01125
gene id: 589873:EP13_RS01125
uniprot id: A0A075NVI7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

589873:EP13 RS17355
gene id: 589873:EP13_RS17355
uniprot id: A0A075P3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS01235
gene id: 589873:EP13_RS01235
uniprot id: A0A075NSD8
names: Similarity
messages: Belongs to the peptidase U62 family.

589873:EP13 RS05515
gene id: 589873:EP13_RS05515
uniprot id: A0A075NXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

589873:EP13 RS04450
gene id: 589873:EP13_RS04450
uniprot id: A0A075NX00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

589873:EP13 RS16530
gene id: 589873:EP13_RS16530
uniprot id: A0A075PA62
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

589873:EP13 RS05155
gene id: 589873:EP13_RS05155
uniprot id: A0A075NXA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

589873:EP13 RS06180
gene id: 589873:EP13_RS06180
uniprot id: A0A075NY44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

589873:EP13 RS12935
gene id: 589873:EP13_RS12935
uniprot id: A0A075P8C8
names: Similarity
messages: Belongs to the asparagine synthetase family.

589873:EP13 RS12485
gene id: 589873:EP13_RS12485
uniprot id: A0A075NXT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

589873:EP13 RS05165
gene id: 589873:EP13_RS05165
uniprot id: A0A075NXH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

589873:EP13 RS01545
gene id: 589873:EP13_RS01545
uniprot id: A0A075NVN1
names: Similarity
messages: Belongs to the HypE family.

589873:EP13 RS08020
gene id: 589873:EP13_RS08020
uniprot id: A0A075P188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

589873:EP13 RS10825
gene id: 589873:EP13_RS10825
uniprot id: A0A075P2H3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

589873:EP13 RS08210
gene id: 589873:EP13_RS08210
uniprot id: A0A075NYR0
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

589873:EP13 RS10665
gene id: 589873:EP13_RS10665
uniprot id: A0A075P2C7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

589873:EP13 RS00530
gene id: 589873:EP13_RS00530
uniprot id: A0A075P1R2
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.

589873:EP13 RS02530
gene id: 589873:EP13_RS02530
uniprot id: A0A075NVZ7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

589873:EP13 RS11630
gene id: 589873:EP13_RS11630
uniprot id: A0A075P0G5
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

589873:EP13 RS11885
gene id: 589873:EP13_RS11885
uniprot id: A0A075P334
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

589873:EP13 RS10120
gene id: 589873:EP13_RS10120
uniprot id: A0A075NZR2
names: Similarity
messages: Belongs to the pirin family.

589873:EP13 RS00470
gene id: 589873:EP13_RS00470
uniprot id: A0A075NXB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS12510
gene id: 589873:EP13_RS12510
uniprot id: A0A075NXT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

589873:EP13 RS17090
gene id: 589873:EP13_RS17090
uniprot id: A0A075P3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

589873:EP13 RS17595
gene id: 589873:EP13_RS17595
uniprot id: A0A350NYJ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS00355
gene id: 589873:EP13_RS00355
uniprot id: A0A075NX72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

589873:EP13 RS02325
gene id: 589873:EP13_RS02325
uniprot id: A0A075NSU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

589873:EP13 RS17170
gene id: 589873:EP13_RS17170
uniprot id: A0A075P3F4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS10925
gene id: 589873:EP13_RS10925
uniprot id: A0A075P7B3
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

589873:EP13 RS10175
gene id: 589873:EP13_RS10175
uniprot id: A0A075NWN3
names: Similarity
messages: Belongs to the DsrF/TusC family.

589873:EP13 RS16350
gene id: 589873:EP13_RS16350
uniprot id: A0A075P2W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

589873:EP13 RS07515
gene id: 589873:EP13_RS07515
uniprot id: A0A075NV95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS01770
gene id: 589873:EP13_RS01770
uniprot id: A0A075NY30
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

589873:EP13 RS04475
gene id: 589873:EP13_RS04475
uniprot id: A0A075NX04
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

589873:EP13 RS17505
gene id: 589873:EP13_RS17505
uniprot id: A0A075P0I9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

589873:EP13 RS02875
gene id: 589873:EP13_RS02875
uniprot id: A0A075NW65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

589873:EP13 RS02005
gene id: 589873:EP13_RS02005
uniprot id: A0A075NVQ1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

589873:EP13 RS03805
gene id: 589873:EP13_RS03805
uniprot id: A0A075NWR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS14340
gene id: 589873:EP13_RS14340
uniprot id: A0A075P1Z0
names: Similarity
messages: Belongs to the YggT family.

589873:EP13 RS18205
gene id: 589873:EP13_RS18205
uniprot id: A0A075P6H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

589873:EP13 RS14190
gene id: 589873:EP13_RS14190
uniprot id: A0A075P242
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

589873:EP13 RS06250
gene id: 589873:EP13_RS06250
uniprot id: A0A075P4W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

589873:EP13 RS18650
gene id: 589873:EP13_RS18650
uniprot id: A0A075P142
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

589873:EP13 RS02445
gene id: 589873:EP13_RS02445
uniprot id: A0A075NSV9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

589873:EP13 RS12725
gene id: 589873:EP13_RS12725
uniprot id: A0A075P113
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

589873:EP13 RS15920
gene id: 589873:EP13_RS15920
uniprot id: A0A075P9V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

589873:EP13 RS17685
gene id: 589873:EP13_RS17685
uniprot id: A0A075P687
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

589873:EP13 RS03375
gene id: 589873:EP13_RS03375
uniprot id: A0A075P3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

589873:EP13 RS04690
gene id: 589873:EP13_RS04690
uniprot id: A0A075NX86
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS05150
gene id: 589873:EP13_RS05150
uniprot id: A0A075NZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

589873:EP13 RS15900
gene id: 589873:EP13_RS15900
uniprot id: A0A075P320
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

589873:EP13 RS16565
gene id: 589873:EP13_RS16565
uniprot id: A0A075P3E6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

589873:EP13 RS16475
gene id: 589873:EP13_RS16475
uniprot id: A0A075P2Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS14320
gene id: 589873:EP13_RS14320
uniprot id: A0A075P944
names: Similarity
messages: Belongs to the GSP E family.

589873:EP13 RS05970
gene id: 589873:EP13_RS05970
uniprot id: A0A075NXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS11335
gene id: 589873:EP13_RS11335
uniprot id: A0A075NX84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

589873:EP13 RS04835
gene id: 589873:EP13_RS04835
uniprot id: A0A075NZQ8
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

589873:EP13 RS05450
gene id: 589873:EP13_RS05450
uniprot id: A0A075NXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS02405
gene id: 589873:EP13_RS02405
uniprot id: A0A075NVY5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

589873:EP13 RS06415
gene id: 589873:EP13_RS06415
uniprot id: A0A075P4Z4
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS01380
gene id: 589873:EP13_RS01380
uniprot id: A0A075NVD4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

589873:EP13 RS07135
gene id: 589873:EP13_RS07135
uniprot id: A0A075P0X2
names: Similarity
messages: Belongs to the ArsC family.

589873:EP13 RS12490
gene id: 589873:EP13_RS12490
uniprot id: A0A075P3C1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

589873:EP13 RS10550
gene id: 589873:EP13_RS10550
uniprot id: A0A075P738
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS01615
gene id: 589873:EP13_RS01615
uniprot id: A0A075NVI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

589873:EP13 RS09880
gene id: 589873:EP13_RS09880
uniprot id: A0A075NZM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

589873:EP13 RS04855
gene id: 589873:EP13_RS04855
uniprot id: A0A075NTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

589873:EP13 RS04700
gene id: 589873:EP13_RS04700
uniprot id: A0A075NZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

589873:EP13 RS16295
gene id: 589873:EP13_RS16295
uniprot id: A0A075P5H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

589873:EP13 RS05420
gene id: 589873:EP13_RS05420
uniprot id: A0A075P021
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

589873:EP13 RS09675
gene id: 589873:EP13_RS09675
uniprot id: A0A075NZK8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

589873:EP13 RS16325
gene id: 589873:EP13_RS16325
uniprot id: A0A075P2V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

589873:EP13 RS07250
gene id: 589873:EP13_RS07250
uniprot id: A0A075NY79
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

589873:EP13 RS13145
gene id: 589873:EP13_RS13145
uniprot id: A0A075P196
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

589873:EP13 RS09615
gene id: 589873:EP13_RS09615
uniprot id: A0A075P6Q3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

589873:EP13 RS07455
gene id: 589873:EP13_RS07455
uniprot id: A0A075P5H8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

589873:EP13 RS14135
gene id: 589873:EP13_RS14135
uniprot id: A0A075P915
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

589873:EP13 RS03280
gene id: 589873:EP13_RS03280
uniprot id: A0A075NWF8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS13895
gene id: 589873:EP13_RS13895
uniprot id: A0A075NYK1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

589873:EP13 RS02920
gene id: 589873:EP13_RS02920
uniprot id: A0A075P327
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

589873:EP13 RS07860
gene id: 589873:EP13_RS07860
uniprot id: A0A075P169
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS03030
gene id: 589873:EP13_RS03030
uniprot id: A0A075NW91
names: Similarity
messages: Belongs to the PhoH family.

589873:EP13 RS04795
gene id: 589873:EP13_RS04795
uniprot id: A0A075P471
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS15450
gene id: 589873:EP13_RS15450
uniprot id: A0A075P4Z5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

589873:EP13 RS18000
gene id: 589873:EP13_RS18000
uniprot id: A0A075P3S7
names: Similarity
messages: Belongs to the CutA family.

589873:EP13 RS17475
gene id: 589873:EP13_RS17475
uniprot id: A0A075P0I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS17120
gene id: 589873:EP13_RS17120
uniprot id: A0A075PAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

589873:EP13 RS16005
gene id: 589873:EP13_RS16005
uniprot id: A0A075NZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

589873:EP13 RS07425
gene id: 589873:EP13_RS07425
uniprot id: A0A075P5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

589873:EP13 RS13640
gene id: 589873:EP13_RS13640
uniprot id: A0A075P3Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

589873:EP13 RS02910
gene id: 589873:EP13_RS02910
uniprot id: A0A075NYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

589873:EP13 RS13785
gene id: 589873:EP13_RS13785
uniprot id: A0A075P1S0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

589873:EP13 RS07985
gene id: 589873:EP13_RS07985
uniprot id: A0A075NYQ5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

589873:EP13 RS18350
gene id: 589873:EP13_RS18350
uniprot id: A0A075P0Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

589873:EP13 RS17005
gene id: 589873:EP13_RS17005
uniprot id: A0A075P5Z4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

589873:EP13 RS04465
gene id: 589873:EP13_RS04465
uniprot id: A0A075NTS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS06855
gene id: 589873:EP13_RS06855
uniprot id: A0A075NYB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

589873:EP13 RS11760
gene id: 589873:EP13_RS11760
uniprot id: A0A350P599
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS06205
gene id: 589873:EP13_RS06205
uniprot id: A0A075NY48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS00745
gene id: 589873:EP13_RS00745
uniprot id: A0A075NS55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS16590
gene id: 589873:EP13_RS16590
uniprot id: A0A075P3F3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

589873:EP13 RS07490
gene id: 589873:EP13_RS07490
uniprot id: A0A075NV90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

589873:EP13 RS16260
gene id: 589873:EP13_RS16260
uniprot id: A0A075P378
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

589873:EP13 RS16055
gene id: 589873:EP13_RS16055
uniprot id: A0A075NZT2
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

589873:EP13 RS14255
gene id: 589873:EP13_RS14255
uniprot id: A0A075NYV3
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS04860
gene id: 589873:EP13_RS04860
uniprot id: A0A075NZR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

589873:EP13 RS02315
gene id: 589873:EP13_RS02315
uniprot id: A0A075NVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

589873:EP13 RS10240
gene id: 589873:EP13_RS10240
uniprot id: A0A075P6Y8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

589873:EP13 RS12625
gene id: 589873:EP13_RS12625
uniprot id: A0A075P862
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

589873:EP13 RS08845
gene id: 589873:EP13_RS08845
uniprot id: A0A075NZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS10765
gene id: 589873:EP13_RS10765
uniprot id: A0A075NWX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS03965
gene id: 589873:EP13_RS03965
uniprot id: A0A075NWT7
names: Similarity
messages: Belongs to the transketolase family.

589873:EP13 RS08670
gene id: 589873:EP13_RS08670
uniprot id: A0A075P670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS09345
gene id: 589873:EP13_RS09345
uniprot id: A0A075P6I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

589873:EP13 RS09370
gene id: 589873:EP13_RS09370
uniprot id: A0A075P6I7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

589873:EP13 RS15600
gene id: 589873:EP13_RS15600
uniprot id: A0A075P2I4
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

589873:EP13 RS14085
gene id: 589873:EP13_RS14085
uniprot id: A0A075P907
names: Similarity
messages: Belongs to the Nudix hydrolase family.

589873:EP13 RS07165
gene id: 589873:EP13_RS07165
uniprot id: A0A075NY62
names: Similarity
messages: Belongs to the Dps family.

589873:EP13 RS01420
gene id: 589873:EP13_RS01420
uniprot id: A0A075NSG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

589873:EP13 RS12530
gene id: 589873:EP13_RS12530
uniprot id: A0A075P131
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

589873:EP13 RS05140
gene id: 589873:EP13_RS05140
uniprot id: A0A075NXH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

589873:EP13 RS18750
gene id: 589873:EP13_RS18750
uniprot id: A0A075P164
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

589873:EP13 RS14145
gene id: 589873:EP13_RS14145
uniprot id: A0A075NYT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

589873:EP13 RS16695
gene id: 589873:EP13_RS16695
uniprot id: A0A075P048
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

589873:EP13 RS16820
gene id: 589873:EP13_RS16820
uniprot id: A0A075P390
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

589873:EP13 RS06260
gene id: 589873:EP13_RS06260
uniprot id: A0A075NUR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

589873:EP13 RS16285
gene id: 589873:EP13_RS16285
uniprot id: A0A075P383
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

589873:EP13 RS05110
gene id: 589873:EP13_RS05110
uniprot id: A0A075P4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS02365
gene id: 589873:EP13_RS02365
uniprot id: A0A075P2R5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

589873:EP13 RS17065
gene id: 589873:EP13_RS17065
uniprot id: A0A075P3D4
names: Similarity
messages: Belongs to the TPP enzyme family.

589873:EP13 RS09650
gene id: 589873:EP13_RS09650
uniprot id: A0A075NZK4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS07155
gene id: 589873:EP13_RS07155
uniprot id: A0A075NV44
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

589873:EP13 RS11020
gene id: 589873:EP13_RS11020
uniprot id: A0A075P2K3
names: Similarity
messages: Belongs to the UPF0502 family.

589873:EP13 RS07825
gene id: 589873:EP13_RS07825
uniprot id: A0A075NYN4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS02305
gene id: 589873:EP13_RS02305
uniprot id: A0A075P2Q6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

589873:EP13 RS18645
gene id: 589873:EP13_RS18645
uniprot id: A0A075P4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS04645
gene id: 589873:EP13_RS04645
uniprot id: A0A075NTV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

589873:EP13 RS06860
gene id: 589873:EP13_RS06860
uniprot id: A0A075NUZ8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

589873:EP13 RS01920
gene id: 589873:EP13_RS01920
uniprot id: A0A075NSM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

589873:EP13 RS07530
gene id: 589873:EP13_RS07530
uniprot id: A0A075P5J4
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

589873:EP13 RS09810
gene id: 589873:EP13_RS09810
uniprot id: A0A075NWI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

589873:EP13 RS18720
gene id: 589873:EP13_RS18720
uniprot id: A0A075P4N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

589873:EP13 RS04915
gene id: 589873:EP13_RS04915
uniprot id: A0A075NX71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

589873:EP13 RS07840
gene id: 589873:EP13_RS07840
uniprot id: A0A075NYI8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

589873:EP13 RS13985
gene id: 589873:EP13_RS13985
uniprot id: A0A075P8U5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

589873:EP13 RS01205
gene id: 589873:EP13_RS01205
uniprot id: A0A075NVJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

589873:EP13 RS01530
gene id: 589873:EP13_RS01530
uniprot id: A0A075NXY2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

589873:EP13 RS18760
gene id: 589873:EP13_RS18760
uniprot id: A0A075P485
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

589873:EP13 RS03025
gene id: 589873:EP13_RS03025
uniprot id: A0A075P348
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

589873:EP13 RS00975
gene id: 589873:EP13_RS00975
uniprot id: A0A075NVG9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

589873:EP13 RS11200
gene id: 589873:EP13_RS11200
uniprot id: A0A075P2N0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

589873:EP13 RS09765
gene id: 589873:EP13_RS09765
uniprot id: A0A075P1Y1
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS13800
gene id: 589873:EP13_RS13800
uniprot id: A0A075P1L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

589873:EP13 RS09455
gene id: 589873:EP13_RS09455
uniprot id: A0A075P6K4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

589873:EP13 RS12730
gene id: 589873:EP13_RS12730
uniprot id: A0A075P884
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS15970
gene id: 589873:EP13_RS15970
uniprot id: A0A075P9W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

589873:EP13 RS03535
gene id: 589873:EP13_RS03535
uniprot id: A0A075NWM1
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

589873:EP13 RS02610
gene id: 589873:EP13_RS02610
uniprot id: A0A075NYK8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

589873:EP13 RS13445
gene id: 589873:EP13_RS13445
uniprot id: A0A075NYA3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

589873:EP13 RS12600
gene id: 589873:EP13_RS12600
uniprot id: A0A075P856
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

589873:EP13 RS09770
gene id: 589873:EP13_RS09770
uniprot id: A0A075NZK6
names: Similarity
messages: Belongs to the peptidase M1 family.

589873:EP13 RS15910
gene id: 589873:EP13_RS15910
uniprot id: A0A075P5A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

589873:EP13 RS02620
gene id: 589873:EP13_RS02620
uniprot id: A0A075P2W1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

589873:EP13 RS09340
gene id: 589873:EP13_RS09340
uniprot id: A0A075NZC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

589873:EP13 RS13840
gene id: 589873:EP13_RS13840
uniprot id: A0A075NYJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS03555
gene id: 589873:EP13_RS03555
uniprot id: A0A075NZ54
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

589873:EP13 RS01025
gene id: 589873:EP13_RS01025
uniprot id: A0A075NVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

589873:EP13 RS03420
gene id: 589873:EP13_RS03420
uniprot id: A0A075NWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

589873:EP13 RS06870
gene id: 589873:EP13_RS06870
uniprot id: A0A075P0T3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS05430
gene id: 589873:EP13_RS05430
uniprot id: A0A075P4I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

589873:EP13 RS15475
gene id: 589873:EP13_RS15475
uniprot id: A0A075P500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS07475
gene id: 589873:EP13_RS07475
uniprot id: A0A075NYC0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

589873:EP13 RS05285
gene id: 589873:EP13_RS05285
uniprot id: A0A075NXD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

589873:EP13 RS12005
gene id: 589873:EP13_RS12005
uniprot id: A0A075P7X2
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS09520
gene id: 589873:EP13_RS09520
uniprot id: A0A075P1U7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

589873:EP13 RS18175
gene id: 589873:EP13_RS18175
uniprot id: A0A075P0W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS08590
gene id: 589873:EP13_RS08590
uniprot id: A0A075NVY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS04875
gene id: 589873:EP13_RS04875
uniprot id: A0A075NXB6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

589873:EP13 RS08515
gene id: 589873:EP13_RS08515
uniprot id: A0A075NYY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS00110
gene id: 589873:EP13_RS00110
uniprot id: A0A075P1F9
names: Similarity
messages: Belongs to the DprA/Smf family.

589873:EP13 RS09145
gene id: 589873:EP13_RS09145
uniprot id: A0A075P1P3
names: Similarity
messages: Belongs to the UPF0434 family.

589873:EP13 RS10660
gene id: 589873:EP13_RS10660
uniprot id: A0A075NWV8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

589873:EP13 RS04950
gene id: 589873:EP13_RS04950
uniprot id: A0A075NXD2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

589873:EP13 RS06480
gene id: 589873:EP13_RS06480
uniprot id: A0A075P0L5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS02965
gene id: 589873:EP13_RS02965
uniprot id: A0A075NW90
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

589873:EP13 RS06015
gene id: 589873:EP13_RS06015
uniprot id: A0A075NUM9
names: Subcellular Location Annotation
messages: Cytoplasm

589873:EP13 RS02890
gene id: 589873:EP13_RS02890
uniprot id: A0A075NW72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS08070
gene id: 589873:EP13_RS08070
uniprot id: A0A075P195
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS00130
gene id: 589873:EP13_RS00130
uniprot id: A0A075NUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

589873:EP13 RS14910
gene id: 589873:EP13_RS14910
uniprot id: A0A075P269
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

589873:EP13 RS16195
gene id: 589873:EP13_RS16195
uniprot id: A0A075PA11
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

589873:EP13 RS15145
gene id: 589873:EP13_RS15145
uniprot id: A0A075P2N4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

589873:EP13 RS00950
gene id: 589873:EP13_RS00950
uniprot id: A0A075NVG8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

589873:EP13 RS18305
gene id: 589873:EP13_RS18305
uniprot id: A0A075P6K0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

589873:EP13 RS03655
gene id: 589873:EP13_RS03655
uniprot id: A0A075NWL9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

589873:EP13 RS08010
gene id: 589873:EP13_RS08010
uniprot id: A0A075NYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

589873:EP13 RS10565
gene id: 589873:EP13_RS10565
uniprot id: A0A075P2A4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

589873:EP13 RS06815
gene id: 589873:EP13_RS06815
uniprot id: A0A075P0S5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS04905
gene id: 589873:EP13_RS04905
uniprot id: A0A075NTX6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

589873:EP13 RS07145
gene id: 589873:EP13_RS07145
uniprot id: A0A075P5D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

589873:EP13 RS12175
gene id: 589873:EP13_RS12175
uniprot id: A0A075NXM6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

589873:EP13 RS08945
gene id: 589873:EP13_RS08945
uniprot id: A0A075P1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

589873:EP13 RS12705
gene id: 589873:EP13_RS12705
uniprot id: A0A075P879
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

589873:EP13 RS06135
gene id: 589873:EP13_RS06135
uniprot id: A0A075NXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

589873:EP13 RS13920
gene id: 589873:EP13_RS13920
uniprot id: A0A075P8T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

589873:EP13 RS03470
gene id: 589873:EP13_RS03470
uniprot id: A0A075NWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

589873:EP13 RS00515
gene id: 589873:EP13_RS00515
uniprot id: A0A075NS15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

589873:EP13 RS15425
gene id: 589873:EP13_RS15425
uniprot id: A0A075P2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

589873:EP13 RS16200
gene id: 589873:EP13_RS16200
uniprot id: A0A075P371
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

589873:EP13 RS06280
gene id: 589873:EP13_RS06280
uniprot id: A0A075P4X1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

589873:EP13 RS03820
gene id: 589873:EP13_RS03820
uniprot id: A0A075NWR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS12360
gene id: 589873:EP13_RS12360
uniprot id: A0A075P0V3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

589873:EP13 RS17660
gene id: 589873:EP13_RS17660
uniprot id: A0A075P3M5
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

589873:EP13 RS18460
gene id: 589873:EP13_RS18460
uniprot id: A0A075P6N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

589873:EP13 RS07735
gene id: 589873:EP13_RS07735
uniprot id: A0A075NYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS11640
gene id: 589873:EP13_RS11640
uniprot id: A0A075P0M4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS17525
gene id: 589873:EP13_RS17525
uniprot id: A0A075P3K6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

589873:EP13 RS15050
gene id: 589873:EP13_RS15050
uniprot id: A0A075P4S2
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

589873:EP13 RS04685
gene id: 589873:EP13_RS04685
uniprot id: A0A075P443
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

589873:EP13 RS14460
gene id: 589873:EP13_RS14460
uniprot id: A0A075NYY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS05495
gene id: 589873:EP13_RS05495
uniprot id: A0A075NU91
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS16185
gene id: 589873:EP13_RS16185
uniprot id: A0A075P5G0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

589873:EP13 RS01570
gene id: 589873:EP13_RS01570
uniprot id: A0A075NVN5
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS05195
gene id: 589873:EP13_RS05195
uniprot id: A0A075NU27
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

589873:EP13 RS11175
gene id: 589873:EP13_RS11175
uniprot id: A0A075P2M6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

589873:EP13 RS16865
gene id: 589873:EP13_RS16865
uniprot id: A0A075P092
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

589873:EP13 RS11220
gene id: 589873:EP13_RS11220
uniprot id: A0A075NX54
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS08345
gene id: 589873:EP13_RS08345
uniprot id: A0A075NYV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

589873:EP13 RS10655
gene id: 589873:EP13_RS10655
uniprot id: A0A075P030
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

589873:EP13 RS03355
gene id: 589873:EP13_RS03355
uniprot id: A0A075NWG8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

589873:EP13 RS17585
gene id: 589873:EP13_RS17585
uniprot id: A0A075PAQ1
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

589873:EP13 RS07325
gene id: 589873:EP13_RS07325
uniprot id: A0A075NY97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS04410
gene id: 589873:EP13_RS04410
uniprot id: A0A075NX41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

589873:EP13 RS07765
gene id: 589873:EP13_RS07765
uniprot id: A0A075P5P3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

589873:EP13 RS07685
gene id: 589873:EP13_RS07685
uniprot id: A0A349TUQ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS14840
gene id: 589873:EP13_RS14840
uniprot id: A0A075P2G7
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

589873:EP13 RS16160
gene id: 589873:EP13_RS16160
uniprot id: A0A075P5F5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS11470
gene id: 589873:EP13_RS11470
uniprot id: A0A075P0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

589873:EP13 RS07215
gene id: 589873:EP13_RS07215
uniprot id: A0A075NV53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

589873:EP13 RS02065
gene id: 589873:EP13_RS02065
uniprot id: A0A075NYA0
names: Similarity
messages: Belongs to the P(II) protein family.

589873:EP13 RS09110
gene id: 589873:EP13_RS09110
uniprot id: A0A075P1N9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

589873:EP13 RS09095
gene id: 589873:EP13_RS09095
uniprot id: A0A075NZA7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

589873:EP13 RS01270
gene id: 589873:EP13_RS01270
uniprot id: A0A075NVB6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS07590
gene id: 589873:EP13_RS07590
uniprot id: A0A075NVB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

589873:EP13 RS14020
gene id: 589873:EP13_RS14020
uniprot id: A0A075NYM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS11345
gene id: 589873:EP13_RS11345
uniprot id: A0A075P0C3
names: Similarity
messages: Belongs to the UxaA family.

589873:EP13 RS13275
gene id: 589873:EP13_RS13275
uniprot id: A0A353JPE5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS03830
gene id: 589873:EP13_RS03830
uniprot id: A0A075NWR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

589873:EP13 RS15030
gene id: 589873:EP13_RS15030
uniprot id: A0A075P2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS15915
gene id: 589873:EP13_RS15915
uniprot id: A0A075P2N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

589873:EP13 RS17050
gene id: 589873:EP13_RS17050
uniprot id: A0A075P3S9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

589873:EP13 RS08730
gene id: 589873:EP13_RS08730
uniprot id: A0A075NZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS04135
gene id: 589873:EP13_RS04135
uniprot id: A0A075NWY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS11655
gene id: 589873:EP13_RS11655
uniprot id: A0A075P0G9
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS01195
gene id: 589873:EP13_RS01195
uniprot id: A0A075NVA4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

589873:EP13 RS18150
gene id: 589873:EP13_RS18150
uniprot id: A0A075P0V7
names: Similarity
messages: Belongs to the HSP15 family.

589873:EP13 RS17710
gene id: 589873:EP13_RS17710
uniprot id: A0A075P692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

589873:EP13 RS09015
gene id: 589873:EP13_RS09015
uniprot id: A0A075P6C5
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

589873:EP13 RS09610
gene id: 589873:EP13_RS09610
uniprot id: A0A075NZH6
names: Similarity
messages: Belongs to the DEAD box helicase family.

589873:EP13 RS08325
gene id: 589873:EP13_RS08325
uniprot id: A0A075NVQ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

589873:EP13 RS17985
gene id: 589873:EP13_RS17985
uniprot id: A0A075P486
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

589873:EP13 RS02415
gene id: 589873:EP13_RS02415
uniprot id: A0A075NYH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

589873:EP13 RS14380
gene id: 589873:EP13_RS14380
uniprot id: A0A075NYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

589873:EP13 RS17250
gene id: 589873:EP13_RS17250
uniprot id: A0A075PAJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

589873:EP13 RS09695
gene id: 589873:EP13_RS09695
uniprot id: A0A075P6R8
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

589873:EP13 RS07090
gene id: 589873:EP13_RS07090
uniprot id: A0A075NY46
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

589873:EP13 RS03590
gene id: 589873:EP13_RS03590
uniprot id: A0A075P3I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

589873:EP13 RS03985
gene id: 589873:EP13_RS03985
uniprot id: A0A075NZB7
names: Similarity
messages: Belongs to the GppA/Ppx family.

589873:EP13 RS10010
gene id: 589873:EP13_RS10010
uniprot id: A0A075P6W4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

589873:EP13 RS01915
gene id: 589873:EP13_RS01915
uniprot id: A0A075NVS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

589873:EP13 RS17085
gene id: 589873:EP13_RS17085
uniprot id: A0A075P604
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

589873:EP13 RS13325
gene id: 589873:EP13_RS13325
uniprot id: A0A075P1C5
names: Similarity
messages: Belongs to the peptidase C56 family.

589873:EP13 RS10345
gene id: 589873:EP13_RS10345
uniprot id: A0A075P702
names: Similarity
messages: Belongs to the SAICAR synthetase family.

589873:EP13 RS13745
gene id: 589873:EP13_RS13745
uniprot id: A0A075P419
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

589873:EP13 RS18005
gene id: 589873:EP13_RS18005
uniprot id: A0A075PAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

589873:EP13 RS01935
gene id: 589873:EP13_RS01935
uniprot id: A0A075P2I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

589873:EP13 RS17460
gene id: 589873:EP13_RS17460
uniprot id: A0A075PAN4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

589873:EP13 RS11680
gene id: 589873:EP13_RS11680
uniprot id: A0A075P0H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

589873:EP13 RS11195
gene id: 589873:EP13_RS11195
uniprot id: A0A075NX49
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

589873:EP13 RS06325
gene id: 589873:EP13_RS06325
uniprot id: A0A075P0I4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

589873:EP13 RS18610
gene id: 589873:EP13_RS18610
uniprot id: A0A075PB85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

589873:EP13 RS08710
gene id: 589873:EP13_RS08710
uniprot id: A0A075NW11
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

589873:EP13 RS02495
gene id: 589873:EP13_RS02495
uniprot id: A0A075NSW9
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

589873:EP13 RS04890
gene id: 589873:EP13_RS04890
uniprot id: A0A075NX68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

589873:EP13 RS03680
gene id: 589873:EP13_RS03680
uniprot id: A0A075NWM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

589873:EP13 RS13980
gene id: 589873:EP13_RS13980
uniprot id: A0A075P1Q2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

589873:EP13 RS12845
gene id: 589873:EP13_RS12845
uniprot id: A0A075P3J1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS04370
gene id: 589873:EP13_RS04370
uniprot id: A0A075NZG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS03825
gene id: 589873:EP13_RS03825
uniprot id: A0A075P3M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

589873:EP13 RS00075
gene id: 589873:EP13_RS00075
uniprot id: A0A075NUL4
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

589873:EP13 RS16050
gene id: 589873:EP13_RS16050
uniprot id: A0A075P349
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

589873:EP13 RS08700
gene id: 589873:EP13_RS08700
uniprot id: A0A353JPN0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS10505
gene id: 589873:EP13_RS10505
uniprot id: A0A075P004
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

589873:EP13 RS10985
gene id: 589873:EP13_RS10985
uniprot id: A0A075NX13
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

589873:EP13 RS06215
gene id: 589873:EP13_RS06215
uniprot id: A0A075P0G6
names: Similarity
messages: Belongs to the asparagine synthetase family.

589873:EP13 RS17890
gene id: 589873:EP13_RS17890
uniprot id: A0A075P3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

589873:EP13 RS11180
gene id: 589873:EP13_RS11180
uniprot id: A0A075P066
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

589873:EP13 RS00680
gene id: 589873:EP13_RS00680
uniprot id: A0A075NV01
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

589873:EP13 RS13015
gene id: 589873:EP13_RS13015
uniprot id: A0A075P3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

589873:EP13 RS08050
gene id: 589873:EP13_RS08050
uniprot id: A0A075NYN2
names: Similarity
messages: Belongs to the SufE family.

589873:EP13 RS01225
gene id: 589873:EP13_RS01225
uniprot id: A0A075P248
names: Similarity
messages: Belongs to the peptidase U62 family.

589873:EP13 RS00035
gene id: 589873:EP13_RS00035
uniprot id: A0A075NV63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

589873:EP13 RS08350
gene id: 589873:EP13_RS08350
uniprot id: A0A075NVR1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

589873:EP13 RS17165
gene id: 589873:EP13_RS17165
uniprot id: A0A075P616
names: Similarity
messages: Belongs to the UPF0047 family.

589873:EP13 RS12025
gene id: 589873:EP13_RS12025
uniprot id: A0A075P355
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

589873:EP13 RS12960
gene id: 589873:EP13_RS12960
uniprot id: A0A075P160
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS12225
gene id: 589873:EP13_RS12225
uniprot id: A0A075NXN5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

589873:EP13 RS16010
gene id: 589873:EP13_RS16010
uniprot id: A0A075P5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

589873:EP13 RS05090
gene id: 589873:EP13_RS05090
uniprot id: A0A075NXG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

589873:EP13 RS01925
gene id: 589873:EP13_RS01925
uniprot id: A0A075NY55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

589873:EP13 RS17350
gene id: 589873:EP13_RS17350
uniprot id: A0A075PAL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

589873:EP13 RS04525
gene id: 589873:EP13_RS04525
uniprot id: A0A350P8K1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS11595
gene id: 589873:EP13_RS11595
uniprot id: A0A075P2Y4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

589873:EP13 RS09150
gene id: 589873:EP13_RS09150
uniprot id: A0A075NZ87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

589873:EP13 RS08240
gene id: 589873:EP13_RS08240
uniprot id: A0A075NYU1
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS18155
gene id: 589873:EP13_RS18155
uniprot id: A0A075P6G5
names: Similarity
messages: Belongs to the GSP C family.

589873:EP13 RS01105
gene id: 589873:EP13_RS01105
uniprot id: A0A075NSB8
names: Similarity
messages: Belongs to the aldose epimerase family.

589873:EP13 RS11410
gene id: 589873:EP13_RS11410
uniprot id: A0A075NX99
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS18170
gene id: 589873:EP13_RS18170
uniprot id: A0A075P4B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

589873:EP13 RS00615
gene id: 589873:EP13_RS00615
uniprot id: A0A075NVD8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

589873:EP13 RS08125
gene id: 589873:EP13_RS08125
uniprot id: A0A075NYP5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

589873:EP13 RS15670
gene id: 589873:EP13_RS15670
uniprot id: A0A075P533
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

589873:EP13 RS09155
gene id: 589873:EP13_RS09155
uniprot id: A0A075P6E6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

589873:EP13 RS17130
gene id: 589873:EP13_RS17130
uniprot id: A0A075P0D3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

589873:EP13 RS14740
gene id: 589873:EP13_RS14740
uniprot id: A0A075NZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

589873:EP13 RS12160
gene id: 589873:EP13_RS12160
uniprot id: A0A075P0R3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

589873:EP13 RS00500
gene id: 589873:EP13_RS00500
uniprot id: A0A075NUX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS00330
gene id: 589873:EP13_RS00330
uniprot id: A0A075NX67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

589873:EP13 RS18335
gene id: 589873:EP13_RS18335
uniprot id: A0A075P3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

589873:EP13 RS02980
gene id: 589873:EP13_RS02980
uniprot id: A0A075NT49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

589873:EP13 RS15735
gene id: 589873:EP13_RS15735
uniprot id: A0A075P2Y5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

589873:EP13 RS04390
gene id: 589873:EP13_RS04390
uniprot id: A0A075NTS1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

589873:EP13 RS06420
gene id: 589873:EP13_RS06420
uniprot id: A0A075NY67
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

589873:EP13 RS10220
gene id: 589873:EP13_RS10220
uniprot id: A0A075NZV3
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

589873:EP13 RS12840
gene id: 589873:EP13_RS12840
uniprot id: A0A075NXZ9
names: Cofactor
messages: Can also use Mn(2+) ion.

589873:EP13 RS11565
gene id: 589873:EP13_RS11565
uniprot id: A0A075P2X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

589873:EP13 RS10900
gene id: 589873:EP13_RS10900
uniprot id: A0A075P069
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

589873:EP13 RS01505
gene id: 589873:EP13_RS01505
uniprot id: A0A075NXX8
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

589873:EP13 RS05280
gene id: 589873:EP13_RS05280
uniprot id: A0A075NZZ8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

589873:EP13 RS01775
gene id: 589873:EP13_RS01775
uniprot id: A0A075NVL1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

589873:EP13 RS06450
gene id: 589873:EP13_RS06450
uniprot id: A0A075NUT8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

589873:EP13 RS17320
gene id: 589873:EP13_RS17320
uniprot id: A0A075P3X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

589873:EP13 RS02165
gene id: 589873:EP13_RS02165
uniprot id: A0A075NYC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS08965
gene id: 589873:EP13_RS08965
uniprot id: A0A075NW58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

589873:EP13 RS00190
gene id: 589873:EP13_RS00190
uniprot id: A0A075NRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

589873:EP13 RS08155
gene id: 589873:EP13_RS08155
uniprot id: A0A075NYQ0
names: Cofactor
messages: Binds 2 iron ions per subunit.

589873:EP13 RS17110
gene id: 589873:EP13_RS17110
uniprot id: A0A075P606
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

589873:EP13 RS06465
gene id: 589873:EP13_RS06465
uniprot id: A0A075P505
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

589873:EP13 RS12355
gene id: 589873:EP13_RS12355
uniprot id: A0A075P396
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

589873:EP13 RS06160
gene id: 589873:EP13_RS06160
uniprot id: A0A075NXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

589873:EP13 RS12700
gene id: 589873:EP13_RS12700
uniprot id: A0A075P107
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

589873:EP13 RS16315
gene id: 589873:EP13_RS16315
uniprot id: A0A075NZY0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

589873:EP13 RS11660
gene id: 589873:EP13_RS11660
uniprot id: A0A075P7R2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS18725
gene id: 589873:EP13_RS18725
uniprot id: A0A075P157
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

589873:EP13 RS12605
gene id: 589873:EP13_RS12605
uniprot id: A0A075P143
names: Similarity
messages: Belongs to the histone deacetylase family.

589873:EP13 RS12040
gene id: 589873:EP13_RS12040
uniprot id: A0A075P0U1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

589873:EP13 RS01525
gene id: 589873:EP13_RS01525
uniprot id: A0A075NSH3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

589873:EP13 RS10670
gene id: 589873:EP13_RS10670
uniprot id: A0A075P005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

589873:EP13 RS00665
gene id: 589873:EP13_RS00665
uniprot id: A0A075NVE1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS09660
gene id: 589873:EP13_RS09660
uniprot id: A0A075P1W7
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

589873:EP13 RS15565
gene id: 589873:EP13_RS15565
uniprot id: A0A075NZH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

589873:EP13 RS12055
gene id: 589873:EP13_RS12055
uniprot id: A0A075P0P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

589873:EP13 RS18010
gene id: 589873:EP13_RS18010
uniprot id: A0A075P490
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

589873:EP13 RS07315
gene id: 589873:EP13_RS07315
uniprot id: A0A075NV69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

589873:EP13 RS14470
gene id: 589873:EP13_RS14470
uniprot id: A0A075P207
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

589873:EP13 RS15960
gene id: 589873:EP13_RS15960
uniprot id: A0A075P5B8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS17255
gene id: 589873:EP13_RS17255
uniprot id: A0A075P3W9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

589873:EP13 RS05305
gene id: 589873:EP13_RS05305
uniprot id: A0A075P4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

589873:EP13 RS18525
gene id: 589873:EP13_RS18525
uniprot id: A0A075P431
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

589873:EP13 RS13425
gene id: 589873:EP13_RS13425
uniprot id: A0A075P1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS11990
gene id: 589873:EP13_RS11990
uniprot id: A0A075P351
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

589873:EP13 RS15340
gene id: 589873:EP13_RS15340
uniprot id: A0A075P2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

589873:EP13 RS08900
gene id: 589873:EP13_RS08900
uniprot id: A0A075NZ40
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

589873:EP13 RS10720
gene id: 589873:EP13_RS10720
uniprot id: A0A075P012
names: Similarity
messages: Belongs to the CvfB family.

589873:EP13 RS05145
gene id: 589873:EP13_RS05145
uniprot id: A0A075NU14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

589873:EP13 RS11330
gene id: 589873:EP13_RS11330
uniprot id: A0A075P0H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

589873:EP13 RS16825
gene id: 589873:EP13_RS16825
uniprot id: A0A075PAD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

589873:EP13 RS04770
gene id: 589873:EP13_RS04770
uniprot id: A0A075NX96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

589873:EP13 RS15800
gene id: 589873:EP13_RS15800
uniprot id: A0A075P2L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS10350
gene id: 589873:EP13_RS10350
uniprot id: A0A075NZX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

589873:EP13 RS18765
gene id: 589873:EP13_RS18765
uniprot id: A0A075PBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

589873:EP13 RS17690
gene id: 589873:EP13_RS17690
uniprot id: A0A075P3N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS05130
gene id: 589873:EP13_RS05130
uniprot id: A0A075NXA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

589873:EP13 RS11585
gene id: 589873:EP13_RS11585
uniprot id: A0A075NXC5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

589873:EP13 RS18085
gene id: 589873:EP13_RS18085
uniprot id: A0A075PAY8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

589873:EP13 RS03155
gene id: 589873:EP13_RS03155
uniprot id: A0A075NWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

589873:EP13 RS10770
gene id: 589873:EP13_RS10770
uniprot id: A0A075P2E9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

589873:EP13 RS09855
gene id: 589873:EP13_RS09855
uniprot id: A0A075P6U6
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

589873:EP13 RS03065
gene id: 589873:EP13_RS03065
uniprot id: A0A075NYU5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

589873:EP13 RS17205
gene id: 589873:EP13_RS17205
uniprot id: A0A075P3V7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

589873:EP13 RS09965
gene id: 589873:EP13_RS09965
uniprot id: A0A075NZR1
names: Similarity
messages: Belongs to the universal stress protein A family.

589873:EP13 RS09760
gene id: 589873:EP13_RS09760
uniprot id: A0A075NWH5
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS11665
gene id: 589873:EP13_RS11665
uniprot id: A0A075P0M9
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS08890
gene id: 589873:EP13_RS08890
uniprot id: A0A075NW46
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

589873:EP13 RS14115
gene id: 589873:EP13_RS14115
uniprot id: A0A075P225
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

589873:EP13 RS17635
gene id: 589873:EP13_RS17635
uniprot id: A0A075P3M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS12695
gene id: 589873:EP13_RS12695
uniprot id: A0A075P3G2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

589873:EP13 RS07500
gene id: 589873:EP13_RS07500
uniprot id: A0A075NYC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS00070
gene id: 589873:EP13_RS00070
uniprot id: A0A075NX15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

589873:EP13 RS02200
gene id: 589873:EP13_RS02200
uniprot id: A0A075NVT8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS03040
gene id: 589873:EP13_RS03040
uniprot id: A0A075NYT9
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

589873:EP13 RS02085
gene id: 589873:EP13_RS02085
uniprot id: A0A075NSQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS13845
gene id: 589873:EP13_RS13845
uniprot id: A0A075P439
names: Function
messages: Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).

589873:EP13 RS08245
gene id: 589873:EP13_RS08245
uniprot id: A0A075NVP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

589873:EP13 RS00645
gene id: 589873:EP13_RS00645
uniprot id: A0A075NS37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

589873:EP13 RS02275
gene id: 589873:EP13_RS02275
uniprot id: A0A075NVV5
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

589873:EP13 RS14435
gene id: 589873:EP13_RS14435
uniprot id: A0A075P4H5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

589873:EP13 RS04020
gene id: 589873:EP13_RS04020
uniprot id: A0A075P3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

589873:EP13 RS01035
gene id: 589873:EP13_RS01035
uniprot id: A0A075NXN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS18200
gene id: 589873:EP13_RS18200
uniprot id: A0A075P0W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

589873:EP13 RS00815
gene id: 589873:EP13_RS00815
uniprot id: A0A075P1W1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

589873:EP13 RS16485
gene id: 589873:EP13_RS16485
uniprot id: A0A075P3C4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

589873:EP13 RS04665
gene id: 589873:EP13_RS04665
uniprot id: A0A075NX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

589873:EP13 RS03440
gene id: 589873:EP13_RS03440
uniprot id: A0A075NZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

589873:EP13 RS12590
gene id: 589873:EP13_RS12590
uniprot id: A0A075P3D7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS13705
gene id: 589873:EP13_RS13705
uniprot id: A0A075P8Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

589873:EP13 RS16845
gene id: 589873:EP13_RS16845
uniprot id: A0A075P395
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

589873:EP13 RS01835
gene id: 589873:EP13_RS01835
uniprot id: A0A349TQ68
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS12690
gene id: 589873:EP13_RS12690
uniprot id: A0A075NXW9
names: Similarity
messages: Belongs to the HesB/IscA family.

589873:EP13 RS18605
gene id: 589873:EP13_RS18605
uniprot id: A0A075P446
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

589873:EP13 RS05415
gene id: 589873:EP13_RS05415
uniprot id: A0A075NU72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

589873:EP13 RS06130
gene id: 589873:EP13_RS06130
uniprot id: A0A075P0F4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

589873:EP13 RS03140
gene id: 589873:EP13_RS03140
uniprot id: A0A075NYZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS15955
gene id: 589873:EP13_RS15955
uniprot id: A0A075NZR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

589873:EP13 RS17325
gene id: 589873:EP13_RS17325
uniprot id: A0A075P0G3
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS05360
gene id: 589873:EP13_RS05360
uniprot id: A0A075NXM1
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS06440
gene id: 589873:EP13_RS06440
uniprot id: A0A075P4Z9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

589873:EP13 RS01040
gene id: 589873:EP13_RS01040
uniprot id: A0A075NV68
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

589873:EP13 RS16210
gene id: 589873:EP13_RS16210
uniprot id: A0A075P5G4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

589873:EP13 RS05240
gene id: 589873:EP13_RS05240
uniprot id: A0A075P4F9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

589873:EP13 RS15025
gene id: 589873:EP13_RS15025
uniprot id: A0A350P7Z4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS08320
gene id: 589873:EP13_RS08320
uniprot id: A0A075NYV0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

589873:EP13 RS14065
gene id: 589873:EP13_RS14065
uniprot id: A0A075P201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

589873:EP13 RS03770
gene id: 589873:EP13_RS03770
uniprot id: A0A075NWQ7
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS08990
gene id: 589873:EP13_RS08990
uniprot id: A0A075NW62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

589873:EP13 RS12495
gene id: 589873:EP13_RS12495
uniprot id: A0A075P0Y0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

589873:EP13 RS12645
gene id: 589873:EP13_RS12645
uniprot id: A0A075P3F0
names: Similarity
messages: Belongs to the YfgM family.

589873:EP13 RS04425
gene id: 589873:EP13_RS04425
uniprot id: A0A075NWZ9
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS05260
gene id: 589873:EP13_RS05260
uniprot id: A0A075NXC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

589873:EP13 RS17075
gene id: 589873:EP13_RS17075
uniprot id: A0A075P3T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

589873:EP13 RS12525
gene id: 589873:EP13_RS12525
uniprot id: A0A075P845
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

589873:EP13 RS06555
gene id: 589873:EP13_RS06555
uniprot id: A0A075P0N0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

589873:EP13 RS12655
gene id: 589873:EP13_RS12655
uniprot id: A0A075P868
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

589873:EP13 RS11970
gene id: 589873:EP13_RS11970
uniprot id: A0A075P0N1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

589873:EP13 RS10250
gene id: 589873:EP13_RS10250
uniprot id: A0A075NWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

589873:EP13 RS11155
gene id: 589873:EP13_RS11155
uniprot id: A0A075P063
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

589873:EP13 RS16850
gene id: 589873:EP13_RS16850
uniprot id: A0A075PAD7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

589873:EP13 RS16290
gene id: 589873:EP13_RS16290
uniprot id: A0A075NZX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

589873:EP13 RS14080
gene id: 589873:EP13_RS14080
uniprot id: A0A075P1V3
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

589873:EP13 RS01285
gene id: 589873:EP13_RS01285
uniprot id: A0A075NSE4
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

589873:EP13 RS01620
gene id: 589873:EP13_RS01620
uniprot id: A0A075P2D2
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS14070
gene id: 589873:EP13_RS14070
uniprot id: A0A075NYR5
names: Similarity
messages: Belongs to the SusD family.

589873:EP13 RS13740
gene id: 589873:EP13_RS13740
uniprot id: A0A075NYG9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

589873:EP13 RS16395
gene id: 589873:EP13_RS16395
uniprot id: A0A075NZZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

589873:EP13 RS10560
gene id: 589873:EP13_RS10560
uniprot id: A0A075NWT9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

589873:EP13 RS04190
gene id: 589873:EP13_RS04190
uniprot id: A0A075P3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS15950
gene id: 589873:EP13_RS15950
uniprot id: A0A075P330
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

589873:EP13 RS14595
gene id: 589873:EP13_RS14595
uniprot id: A0A075P222
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

589873:EP13 RS03230
gene id: 589873:EP13_RS03230
uniprot id: A0A075NWE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

589873:EP13 RS06885
gene id: 589873:EP13_RS06885
uniprot id: A0A075NYB4
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

589873:EP13 RS12670
gene id: 589873:EP13_RS12670
uniprot id: A0A075P3F6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

589873:EP13 RS12210
gene id: 589873:EP13_RS12210
uniprot id: A0A075P0S4
names: Similarity
messages: Belongs to the MotB family.

589873:EP13 RS17375
gene id: 589873:EP13_RS17375
uniprot id: A0A075PAL9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS05460
gene id: 589873:EP13_RS05460
uniprot id: A0A075NXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

589873:EP13 RS16835
gene id: 589873:EP13_RS16835
uniprot id: A0A075P089
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

589873:EP13 RS17895
gene id: 589873:EP13_RS17895
uniprot id: A0A075PAV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

589873:EP13 RS02590
gene id: 589873:EP13_RS02590
uniprot id: A0A075NW08
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS09895
gene id: 589873:EP13_RS09895
uniprot id: A0A075NWJ8
names: Similarity
messages: Belongs to the glutamate synthase family.

589873:EP13 RS08950
gene id: 589873:EP13_RS08950
uniprot id: A0A075NZ51
names: Similarity
messages: Belongs to the peptidase S16 family.

589873:EP13 RS14425
gene id: 589873:EP13_RS14425
uniprot id: A0A075P289
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

589873:EP13 RS04245
gene id: 589873:EP13_RS04245
uniprot id: A0A075NX11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

589873:EP13 RS09310
gene id: 589873:EP13_RS09310
uniprot id: A0A075P1R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

589873:EP13 RS15095
gene id: 589873:EP13_RS15095
uniprot id: A0A075P2M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

589873:EP13 RS06565
gene id: 589873:EP13_RS06565
uniprot id: A0A075P524
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

589873:EP13 RS04675
gene id: 589873:EP13_RS04675
uniprot id: A0A075NZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

589873:EP13 RS12365
gene id: 589873:EP13_RS12365
uniprot id: A0A075P815
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

589873:EP13 RS03620
gene id: 589873:EP13_RS03620
uniprot id: A0A075P3I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

589873:EP13 RS17545
gene id: 589873:EP13_RS17545
uniprot id: A0A075P661
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS18475
gene id: 589873:EP13_RS18475
uniprot id: A0A075P4I6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

589873:EP13 RS00675
gene id: 589873:EP13_RS00675
uniprot id: A0A075NXG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

589873:EP13 RS06915
gene id: 589873:EP13_RS06915
uniprot id: A0A075NYB5
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS14780
gene id: 589873:EP13_RS14780
uniprot id: A0A075P9C2
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

589873:EP13 RS18185
gene id: 589873:EP13_RS18185
uniprot id: A0A075P3W2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

589873:EP13 RS03380
gene id: 589873:EP13_RS03380
uniprot id: A0A075NWH4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

589873:EP13 RS12620
gene id: 589873:EP13_RS12620
uniprot id: A0A075P0Z5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

589873:EP13 RS08480
gene id: 589873:EP13_RS08480
uniprot id: A0A075NYX5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

589873:EP13 RS04725
gene id: 589873:EP13_RS04725
uniprot id: A0A075NZN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

589873:EP13 RS12390
gene id: 589873:EP13_RS12390
uniprot id: A0A075P0V9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

589873:EP13 RS13190
gene id: 589873:EP13_RS13190
uniprot id: A0A075P1H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

589873:EP13 RS07230
gene id: 589873:EP13_RS07230
uniprot id: A0A075P5E8
names: PTM
messages: Binds 1 heme group per subunit.

589873:EP13 RS02535
gene id: 589873:EP13_RS02535
uniprot id: A0A075P2U5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS02440
gene id: 589873:EP13_RS02440
uniprot id: A0A075NVY9
names: Similarity
messages: Belongs to the UPF0438 family.

589873:EP13 RS07615
gene id: 589873:EP13_RS07615
uniprot id: A0A075NVC0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

589873:EP13 RS14335
gene id: 589873:EP13_RS14335
uniprot id: A0A075P4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

589873:EP13 RS16790
gene id: 589873:EP13_RS16790
uniprot id: A0A075P386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

589873:EP13 RS14430
gene id: 589873:EP13_RS14430
uniprot id: A0A075NYX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS10865
gene id: 589873:EP13_RS10865
uniprot id: A0A075P7A3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS14510
gene id: 589873:EP13_RS14510
uniprot id: A0A075NYY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS00115
gene id: 589873:EP13_RS00115
uniprot id: A0A075NV74
names: Similarity
messages: Belongs to the Smg family.

589873:EP13 RS01155
gene id: 589873:EP13_RS01155
uniprot id: A0A075NSC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

589873:EP13 RS16365
gene id: 589873:EP13_RS16365
uniprot id: A0A075NZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

589873:EP13 RS10700
gene id: 589873:EP13_RS10700
uniprot id: A0A075P775
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

589873:EP13 RS14640
gene id: 589873:EP13_RS14640
uniprot id: A0A075NZ02
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

589873:EP13 RS12035
gene id: 589873:EP13_RS12035
uniprot id: A0A075P7X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

589873:EP13 RS07820
gene id: 589873:EP13_RS07820
uniprot id: A0A075P5Q4
names: Similarity
messages: Belongs to the fructosamine kinase family.

589873:EP13 RS08290
gene id: 589873:EP13_RS08290
uniprot id: A0A075NYU7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

589873:EP13 RS07225
gene id: 589873:EP13_RS07225
uniprot id: A0A075NY72
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

589873:EP13 RS07550
gene id: 589873:EP13_RS07550
uniprot id: A0A075NYD6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

589873:EP13 RS18220
gene id: 589873:EP13_RS18220
uniprot id: A0A075P4C9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

589873:EP13 RS08470
gene id: 589873:EP13_RS08470
uniprot id: A0A075NYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

589873:EP13 RS06240
gene id: 589873:EP13_RS06240
uniprot id: A0A075P0H0
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS02075
gene id: 589873:EP13_RS02075
uniprot id: A0A075P2K4
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

589873:EP13 RS10110
gene id: 589873:EP13_RS10110
uniprot id: A0A075NWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

589873:EP13 RS02615
gene id: 589873:EP13_RS02615
uniprot id: A0A075NW15
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

589873:EP13 RS09305
gene id: 589873:EP13_RS09305
uniprot id: A0A075NWB1
names: Similarity
messages: Belongs to the citrate synthase family.

589873:EP13 RS18455
gene id: 589873:EP13_RS18455
uniprot id: A0A075P114
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

589873:EP13 RS13360
gene id: 589873:EP13_RS13360
uniprot id: A0A075P1J8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

589873:EP13 RS15440
gene id: 589873:EP13_RS15440
uniprot id: A0A075P2T3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS03090
gene id: 589873:EP13_RS03090
uniprot id: A0A075NYX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

589873:EP13 RS07245
gene id: 589873:EP13_RS07245
uniprot id: A0A075P0Y8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

589873:EP13 RS14775
gene id: 589873:EP13_RS14775
uniprot id: A0A075P247
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS02505
gene id: 589873:EP13_RS02505
uniprot id: A0A075NVZ2
names: Similarity
messages: Belongs to the thioredoxin family.

589873:EP13 RS17840
gene id: 589873:EP13_RS17840
uniprot id: A0A075P0P9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

589873:EP13 RS09755
gene id: 589873:EP13_RS09755
uniprot id: A0A075NZM3
names: Similarity
messages: Belongs to the peptidase S41A family.

589873:EP13 RS04015
gene id: 589873:EP13_RS04015
uniprot id: A0A075NWU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

589873:EP13 RS14325
gene id: 589873:EP13_RS14325
uniprot id: A0A075P268
names: Similarity
messages: Belongs to the GSP E family.

589873:EP13 RS03915
gene id: 589873:EP13_RS03915
uniprot id: A0A075P3N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

589873:EP13 RS02745
gene id: 589873:EP13_RS02745
uniprot id: A0A075NYN5
names: Similarity
messages: Belongs to the RelE toxin family.

589873:EP13 RS08115
gene id: 589873:EP13_RS08115
uniprot id: A0A075NVM3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS09625
gene id: 589873:EP13_RS09625
uniprot id: A0A075NWF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS08745
gene id: 589873:EP13_RS08745
uniprot id: A0A075NZ12
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

589873:EP13 RS05030
gene id: 589873:EP13_RS05030
uniprot id: A0A075P4B4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

589873:EP13 RS10585
gene id: 589873:EP13_RS10585
uniprot id: A0A075NWU4
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

589873:EP13 RS13750
gene id: 589873:EP13_RS13750
uniprot id: A0A075P1J6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS17210
gene id: 589873:EP13_RS17210
uniprot id: A0A075P0E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

589873:EP13 RS11165
gene id: 589873:EP13_RS11165
uniprot id: A0A075P0B0
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

589873:EP13 RS02320
gene id: 589873:EP13_RS02320
uniprot id: A0A358DVB6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS03720
gene id: 589873:EP13_RS03720
uniprot id: A0A075NWP8
names: Subcellular Location Annotation
messages: Cytoplasm

589873:EP13 RS12015
gene id: 589873:EP13_RS12015
uniprot id: A0A075P0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS18480
gene id: 589873:EP13_RS18480
uniprot id: A0A075P119
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS17795
gene id: 589873:EP13_RS17795
uniprot id: A0A075P6A7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS10165
gene id: 589873:EP13_RS10165
uniprot id: A0A075P6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

589873:EP13 RS12340
gene id: 589873:EP13_RS12340
uniprot id: A0A075P811
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

589873:EP13 RS04400
gene id: 589873:EP13_RS04400
uniprot id: A0A075NWZ5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

589873:EP13 RS11040
gene id: 589873:EP13_RS11040
uniprot id: A0A075NX23
names: Similarity
messages: Belongs to the UPF0438 family.

589873:EP13 RS18735
gene id: 589873:EP13_RS18735
uniprot id: A0A075P480
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

589873:EP13 RS08935
gene id: 589873:EP13_RS08935
uniprot id: A0A075NZ80
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

589873:EP13 RS12765
gene id: 589873:EP13_RS12765
uniprot id: A0A075NXY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

589873:EP13 RS00560
gene id: 589873:EP13_RS00560
uniprot id: A0A349TTW0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS02040
gene id: 589873:EP13_RS02040
uniprot id: A0A358E1H8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS01005
gene id: 589873:EP13_RS01005
uniprot id: A0A075NSA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

589873:EP13 RS03780
gene id: 589873:EP13_RS03780
uniprot id: A0A075NWQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

589873:EP13 RS15595
gene id: 589873:EP13_RS15595
uniprot id: A0A075P521
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

589873:EP13 RS09115
gene id: 589873:EP13_RS09115
uniprot id: A0A075NZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

589873:EP13 RS16575
gene id: 589873:EP13_RS16575
uniprot id: A0A075P5M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

589873:EP13 RS00465
gene id: 589873:EP13_RS00465
uniprot id: A0A075NS04
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS15180
gene id: 589873:EP13_RS15180
uniprot id: A0A075P4U4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

589873:EP13 RS02525
gene id: 589873:EP13_RS02525
uniprot id: A0A075NYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

589873:EP13 RS07700
gene id: 589873:EP13_RS07700
uniprot id: A0A075NYL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

589873:EP13 RS18490
gene id: 589873:EP13_RS18490
uniprot id: A0A349TWN2
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS04920
gene id: 589873:EP13_RS04920
uniprot id: A0A075P497
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

589873:EP13 RS07990
gene id: 589873:EP13_RS07990
uniprot id: A0A075NVJ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

589873:EP13 RS07510
gene id: 589873:EP13_RS07510
uniprot id: A0A075NYJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

589873:EP13 RS15100
gene id: 589873:EP13_RS15100
uniprot id: A0A075NZ83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

589873:EP13 RS15705
gene id: 589873:EP13_RS15705
uniprot id: A0A075P9T6
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS05050
gene id: 589873:EP13_RS05050
uniprot id: A0A075NX88
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

589873:EP13 RS14665
gene id: 589873:EP13_RS14665
uniprot id: A0A075P9A3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

589873:EP13 RS04865
gene id: 589873:EP13_RS04865
uniprot id: A0A075NX64
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

589873:EP13 RS10195
gene id: 589873:EP13_RS10195
uniprot id: A0A075NZU9
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

589873:EP13 RS07075
gene id: 589873:EP13_RS07075
uniprot id: A0A075NYC8
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

589873:EP13 RS18195
gene id: 589873:EP13_RS18195
uniprot id: A0A075P4C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS05400
gene id: 589873:EP13_RS05400
uniprot id: A0A075NXF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS09795
gene id: 589873:EP13_RS09795
uniprot id: A0A075NZL1
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS01930
gene id: 589873:EP13_RS01930
uniprot id: A0A075NVN8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

589873:EP13 RS04870
gene id: 589873:EP13_RS04870
uniprot id: A0A075P488
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

589873:EP13 RS06320
gene id: 589873:EP13_RS06320
uniprot id: A0A075NUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

589873:EP13 RS03070
gene id: 589873:EP13_RS03070
uniprot id: A0A075NWB4
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

589873:EP13 RS06950
gene id: 589873:EP13_RS06950
uniprot id: A0A075P595
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

589873:EP13 RS11795
gene id: 589873:EP13_RS11795
uniprot id: A0A075P0Q1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

589873:EP13 RS09045
gene id: 589873:EP13_RS09045
uniprot id: A0A075NZ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS04925
gene id: 589873:EP13_RS04925
uniprot id: A0A075NXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

589873:EP13 RS16310
gene id: 589873:EP13_RS16310
uniprot id: A0A075P388
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

589873:EP13 RS06455
gene id: 589873:EP13_RS06455
uniprot id: A0A075P0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

589873:EP13 RS02385
gene id: 589873:EP13_RS02385
uniprot id: A0A353JNF0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS08835
gene id: 589873:EP13_RS08835
uniprot id: A0A075NW35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

589873:EP13 RS08810
gene id: 589873:EP13_RS08810
uniprot id: A0A075NW30
names: Subcellular Location Annotation
messages: Cytoplasm

589873:EP13 RS06490
gene id: 589873:EP13_RS06490
uniprot id: A0A075P511
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

589873:EP13 RS19185
gene id: 589873:EP13_RS19185
uniprot id: A0A353JM71
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS13070
gene id: 589873:EP13_RS13070
uniprot id: A0A075P183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

589873:EP13 RS18095
gene id: 589873:EP13_RS18095
uniprot id: A0A075P0U4
names: Similarity
messages: Belongs to the GARS family.

589873:EP13 RS07835
gene id: 589873:EP13_RS07835
uniprot id: A0A075P166
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

589873:EP13 RS00585
gene id: 589873:EP13_RS00585
uniprot id: A0A075P1S2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS17105
gene id: 589873:EP13_RS17105
uniprot id: A0A075P0C9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

589873:EP13 RS02150
gene id: 589873:EP13_RS02150
uniprot id: A0A075P2M2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

589873:EP13 RS00460
gene id: 589873:EP13_RS00460
uniprot id: A0A075NVC5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS13795
gene id: 589873:EP13_RS13795
uniprot id: A0A075P428
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

589873:EP13 RS03545
gene id: 589873:EP13_RS03545
uniprot id: A0A075NWJ9
names: Similarity
messages: Belongs to the aspartokinase family.

589873:EP13 RS05220
gene id: 589873:EP13_RS05220
uniprot id: A0A075NU34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

589873:EP13 RS11980
gene id: 589873:EP13_RS11980
uniprot id: A0A075P0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

589873:EP13 RS09655
gene id: 589873:EP13_RS09655
uniprot id: A0A075NWF7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

589873:EP13 RS14100
gene id: 589873:EP13_RS14100
uniprot id: A0A075P4B0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

589873:EP13 RS03580
gene id: 589873:EP13_RS03580
uniprot id: A0A075NZ59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

589873:EP13 RS01405
gene id: 589873:EP13_RS01405
uniprot id: A0A075NVD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

589873:EP13 RS17860
gene id: 589873:EP13_RS17860
uniprot id: A0A075P3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS09885
gene id: 589873:EP13_RS09885
uniprot id: A0A075P6V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

589873:EP13 RS06410
gene id: 589873:EP13_RS06410
uniprot id: A0A075NXV7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS12240
gene id: 589873:EP13_RS12240
uniprot id: A0A075P7Z9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

589873:EP13 RS14075
gene id: 589873:EP13_RS14075
uniprot id: A0A075P4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS08805
gene id: 589873:EP13_RS08805
uniprot id: A0A075NZ53
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

589873:EP13 RS16620
gene id: 589873:EP13_RS16620
uniprot id: A0A075P032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

589873:EP13 RS07320
gene id: 589873:EP13_RS07320
uniprot id: A0A075P105
names: Similarity
messages: Belongs to the PhoH family.

589873:EP13 RS16080
gene id: 589873:EP13_RS16080
uniprot id: A0A075P353
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS03980
gene id: 589873:EP13_RS03980
uniprot id: A0A075NTL6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

589873:EP13 RS04385
gene id: 589873:EP13_RS04385
uniprot id: A0A075NX36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS16765
gene id: 589873:EP13_RS16765
uniprot id: A0A075PAC7
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

589873:EP13 RS04610
gene id: 589873:EP13_RS04610
uniprot id: A0A075NX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS05810
gene id: 589873:EP13_RS05810
uniprot id: A0A075NXZ4
names: Similarity
messages: Belongs to the Gfa family.

589873:EP13 RS09945
gene id: 589873:EP13_RS09945
uniprot id: A0A075NWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

589873:EP13 RS11215
gene id: 589873:EP13_RS11215
uniprot id: A0A075P0C1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

589873:EP13 RS17960
gene id: 589873:EP13_RS17960
uniprot id: A0A075P482
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS16785
gene id: 589873:EP13_RS16785
uniprot id: A0A075P5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS02470
gene id: 589873:EP13_RS02470
uniprot id: A0A075NSW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

589873:EP13 RS03690
gene id: 589873:EP13_RS03690
uniprot id: A0A075NZ75
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

589873:EP13 RS11580
gene id: 589873:EP13_RS11580
uniprot id: A0A075P0L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

589873:EP13 RS16915
gene id: 589873:EP13_RS16915
uniprot id: A0A075P3Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

589873:EP13 RS03255
gene id: 589873:EP13_RS03255
uniprot id: A0A075NWF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

589873:EP13 RS07115
gene id: 589873:EP13_RS07115
uniprot id: A0A075NY50
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

589873:EP13 RS16420
gene id: 589873:EP13_RS16420
uniprot id: A0A075NZZ6
names: Similarity
messages: Belongs to the SCO1/2 family.

589873:EP13 RS13830
gene id: 589873:EP13_RS13830
uniprot id: A0A075P8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS09430
gene id: 589873:EP13_RS09430
uniprot id: A0A075NZH0
names: Similarity
messages: Belongs to the peptidase S49 family.

589873:EP13 RS10390
gene id: 589873:EP13_RS10390
uniprot id: A0A075NZV7
names: Similarity
messages: Belongs to the WrbA family.

589873:EP13 RS07670
gene id: 589873:EP13_RS07670
uniprot id: A0A358E3K5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS12635
gene id: 589873:EP13_RS12635
uniprot id: A0A075P150
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

589873:EP13 RS09735
gene id: 589873:EP13_RS09735
uniprot id: A0A350P6T3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS09090
gene id: 589873:EP13_RS09090
uniprot id: A0A075P6D9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

589873:EP13 RS08885
gene id: 589873:EP13_RS08885
uniprot id: A0A075NZ68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

589873:EP13 RS07465
gene id: 589873:EP13_RS07465
uniprot id: A0A075NV85
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

589873:EP13 RS10145
gene id: 589873:EP13_RS10145
uniprot id: A0A075NWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

589873:EP13 RS08915
gene id: 589873:EP13_RS08915
uniprot id: A0A075NW48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

589873:EP13 RS10745
gene id: 589873:EP13_RS10745
uniprot id: A0A075P2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS16605
gene id: 589873:EP13_RS16605
uniprot id: A0A075P311
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS13025
gene id: 589873:EP13_RS13025
uniprot id: A0A075P8E3
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS02070
gene id: 589873:EP13_RS02070
uniprot id: A0A075NVR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

589873:EP13 RS08260
gene id: 589873:EP13_RS08260
uniprot id: A0A075P5Z2
names: Similarity
messages: Belongs to the intimin/invasin family.

589873:EP13 RS11145
gene id: 589873:EP13_RS11145
uniprot id: A0A075NX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS11530
gene id: 589873:EP13_RS11530
uniprot id: A0A075NXB7
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS17880
gene id: 589873:EP13_RS17880
uniprot id: A0A075P6C0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

589873:EP13 RS00295
gene id: 589873:EP13_RS00295
uniprot id: A0A075NV96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

589873:EP13 RS17100
gene id: 589873:EP13_RS17100
uniprot id: A0A075P3T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

589873:EP13 RS00630
gene id: 589873:EP13_RS00630
uniprot id: A0A075NUZ1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

589873:EP13 RS14575
gene id: 589873:EP13_RS14575
uniprot id: A0A075P989
names: Similarity
messages: Belongs to the citrate synthase family.

589873:EP13 RS02580
gene id: 589873:EP13_RS02580
uniprot id: A0A075NSY0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

589873:EP13 RS13340
gene id: 589873:EP13_RS13340
uniprot id: A0A075NY82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS04050
gene id: 589873:EP13_RS04050
uniprot id: A0A075NWX5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

589873:EP13 RS06985
gene id: 589873:EP13_RS06985
uniprot id: A0A075P0U7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

589873:EP13 RS00065
gene id: 589873:EP13_RS00065
uniprot id: A0A075NRQ4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

589873:EP13 RS03650
gene id: 589873:EP13_RS03650
uniprot id: A0A075P3J3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

589873:EP13 RS16730
gene id: 589873:EP13_RS16730
uniprot id: A0A075P5R3
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

589873:EP13 RS17435
gene id: 589873:EP13_RS17435
uniprot id: A0A075PAM8
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS07420
gene id: 589873:EP13_RS07420
uniprot id: A0A075NYA7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

589873:EP13 RS07880
gene id: 589873:EP13_RS07880
uniprot id: A0A075NYP1
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS18165
gene id: 589873:EP13_RS18165
uniprot id: A0A075PB00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

589873:EP13 RS03550
gene id: 589873:EP13_RS03550
uniprot id: A0A075NTH4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

589873:EP13 RS08315
gene id: 589873:EP13_RS08315
uniprot id: A0A075P605
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

589873:EP13 RS04330
gene id: 589873:EP13_RS04330
uniprot id: A0A075P3X5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

589873:EP13 RS06540
gene id: 589873:EP13_RS06540
uniprot id: A0A075P518
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

589873:EP13 RS09500
gene id: 589873:EP13_RS09500
uniprot id: A0A075NZF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

589873:EP13 RS18730
gene id: 589873:EP13_RS18730
uniprot id: A0A075P6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

589873:EP13 RS11210
gene id: 589873:EP13_RS11210
uniprot id: A0A075P7I2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

589873:EP13 RS14925
gene id: 589873:EP13_RS14925
uniprot id: A0A075P2I1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

589873:EP13 RS08335
gene id: 589873:EP13_RS08335
uniprot id: A0A075NYT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

589873:EP13 RS04510
gene id: 589873:EP13_RS04510
uniprot id: A0A075NX61
names: Similarity
messages: Belongs to the ABC transporter superfamily.

589873:EP13 RS08715
gene id: 589873:EP13_RS08715
uniprot id: A0A075P1K7
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

589873:EP13 RS05880
gene id: 589873:EP13_RS05880
uniprot id: A0A075NY02
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

589873:EP13 RS14035
gene id: 589873:EP13_RS14035
uniprot id: A0A075P8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

589873:EP13 RS11850
gene id: 589873:EP13_RS11850
uniprot id: A0A075P0Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

589873:EP13 RS18615
gene id: 589873:EP13_RS18615
uniprot id: A0A075P4L4
names: Similarity
messages: Belongs to the YicC/YloC family.

589873:EP13 RS06610
gene id: 589873:EP13_RS06610
uniprot id: A0A075NY86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

589873:EP13 RS17675
gene id: 589873:EP13_RS17675
uniprot id: A0A075P430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS11985
gene id: 589873:EP13_RS11985
uniprot id: A0A075NXJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

589873:EP13 RS03675
gene id: 589873:EP13_RS03675
uniprot id: A0A075P3J9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

589873:EP13 RS13770
gene id: 589873:EP13_RS13770
uniprot id: A0A075P424
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

589873:EP13 RS12380
gene id: 589873:EP13_RS12380
uniprot id: A0A075NXR5
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

589873:EP13 RS12250
gene id: 589873:EP13_RS12250
uniprot id: A0A075NXP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

589873:EP13 RS00280
gene id: 589873:EP13_RS00280
uniprot id: A0A075NX58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

589873:EP13 RS14940
gene id: 589873:EP13_RS14940
uniprot id: A0A075P274
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

589873:EP13 RS02885
gene id: 589873:EP13_RS02885
uniprot id: A0A075NYQ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

589873:EP13 RS02550
gene id: 589873:EP13_RS02550
uniprot id: A0A075NW06
names: Similarity
messages: Belongs to the Dps family.

589873:EP13 RS14405
gene id: 589873:EP13_RS14405
uniprot id: A0A075NYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

589873:EP13 RS15860
gene id: 589873:EP13_RS15860
uniprot id: A0A075P594
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS02575
gene id: 589873:EP13_RS02575
uniprot id: A0A075NW10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

589873:EP13 RS04585
gene id: 589873:EP13_RS04585
uniprot id: A0A075NX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

589873:EP13 RS11380
gene id: 589873:EP13_RS11380
uniprot id: A0A075P0I6
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

589873:EP13 RS04760
gene id: 589873:EP13_RS04760
uniprot id: A0A075NX45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

589873:EP13 RS18015
gene id: 589873:EP13_RS18015
uniprot id: A0A075P0T0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

589873:EP13 RS08535
gene id: 589873:EP13_RS08535
uniprot id: A0A075P636
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

589873:EP13 RS05245
gene id: 589873:EP13_RS05245
uniprot id: A0A075NXJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

589873:EP13 RS01075
gene id: 589873:EP13_RS01075
uniprot id: A0A075NVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

589873:EP13 RS10630
gene id: 589873:EP13_RS10630
uniprot id: A0A075P027
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS04375
gene id: 589873:EP13_RS04375
uniprot id: A0A075NWZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

589873:EP13 RS15335
gene id: 589873:EP13_RS15335
uniprot id: A0A075P4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

589873:EP13 RS10270
gene id: 589873:EP13_RS10270
uniprot id: A0A075NZW2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

589873:EP13 RS01070
gene id: 589873:EP13_RS01070
uniprot id: A0A075P211
names: Similarity
messages: Belongs to the heat shock protein 70 family.

589873:EP13 RS04680
gene id: 589873:EP13_RS04680
uniprot id: A0A075NX31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

589873:EP13 RS16760
gene id: 589873:EP13_RS16760
uniprot id: A0A075P368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS14870
gene id: 589873:EP13_RS14870
uniprot id: A0A075P2H0
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS00655
gene id: 589873:EP13_RS00655
uniprot id: A0A075NUZ6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

589873:EP13 RS12280
gene id: 589873:EP13_RS12280
uniprot id: A0A075P380
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

589873:EP13 RS10355
gene id: 589873:EP13_RS10355
uniprot id: A0A075NWQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

589873:EP13 RS06155
gene id: 589873:EP13_RS06155
uniprot id: A0A075P0F9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

589873:EP13 RS01220
gene id: 589873:EP13_RS01220
uniprot id: A0A075NVA9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

589873:EP13 RS11560
gene id: 589873:EP13_RS11560
uniprot id: A0A075NXC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS02785
gene id: 589873:EP13_RS02785
uniprot id: A0A075P2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

589873:EP13 RS13385
gene id: 589873:EP13_RS13385
uniprot id: A0A075P3U2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS08255
gene id: 589873:EP13_RS08255
uniprot id: A0A075NYR4
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS01940
gene id: 589873:EP13_RS01940
uniprot id: A0A075NVS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

589873:EP13 RS06810
gene id: 589873:EP13_RS06810
uniprot id: A0A075NUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

589873:EP13 RS05125
gene id: 589873:EP13_RS05125
uniprot id: A0A075NZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

589873:EP13 RS13400
gene id: 589873:EP13_RS13400
uniprot id: A0A075P8K4
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS18785
gene id: 589873:EP13_RS18785
uniprot id: A0A075P489
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS14410
gene id: 589873:EP13_RS14410
uniprot id: A0A075P4H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

589873:EP13 RS18390
gene id: 589873:EP13_RS18390
uniprot id: A0A075PB42
names: Similarity
messages: Belongs to the SCO1/2 family.

589873:EP13 RS14015
gene id: 589873:EP13_RS14015
uniprot id: A0A075P1W6
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

589873:EP13 RS12930
gene id: 589873:EP13_RS12930
uniprot id: A0A075P154
names: Similarity
messages: Belongs to the FemABX family.

589873:EP13 RS05275
gene id: 589873:EP13_RS05275
uniprot id: A0A075NU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

589873:EP13 RS12770
gene id: 589873:EP13_RS12770
uniprot id: A0A075P3H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

589873:EP13 RS02120
gene id: 589873:EP13_RS02120
uniprot id: A0A075NVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

589873:EP13 RS10695
gene id: 589873:EP13_RS10695
uniprot id: A0A075P010
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS11320
gene id: 589873:EP13_RS11320
uniprot id: A0A075P0B5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

589873:EP13 RS14830
gene id: 589873:EP13_RS14830
uniprot id: A0A075P256
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

589873:EP13 RS01755
gene id: 589873:EP13_RS01755
uniprot id: A0A075P2F3
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

589873:EP13 RS02290
gene id: 589873:EP13_RS02290
uniprot id: A0A075NST8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

589873:EP13 RS09935
gene id: 589873:EP13_RS09935
uniprot id: A0A075P6V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

589873:EP13 RS03465
gene id: 589873:EP13_RS03465
uniprot id: A0A075NZ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

589873:EP13 RS01400
gene id: 589873:EP13_RS01400
uniprot id: A0A075NXV8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS14610
gene id: 589873:EP13_RS14610
uniprot id: A0A075NYZ9
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

589873:EP13 RS06545
gene id: 589873:EP13_RS06545
uniprot id: A0A075NY80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

589873:EP13 RS14660
gene id: 589873:EP13_RS14660
uniprot id: A0A075P231
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS13315
gene id: 589873:EP13_RS13315
uniprot id: A0A075NY74
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. Sucrose phosphorylase subfamily.

589873:EP13 RS03125
gene id: 589873:EP13_RS03125
uniprot id: A0A075P392
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

589873:EP13 RS14295
gene id: 589873:EP13_RS14295
uniprot id: A0A075P940
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

589873:EP13 RS02860
gene id: 589873:EP13_RS02860
uniprot id: A0A075NYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

589873:EP13 RS01905
gene id: 589873:EP13_RS01905
uniprot id: A0A075NVN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

589873:EP13 RS04880
gene id: 589873:EP13_RS04880
uniprot id: A0A075NTX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

589873:EP13 RS18240
gene id: 589873:EP13_RS18240
uniprot id: A0A075PB16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

589873:EP13 RS00980
gene id: 589873:EP13_RS00980
uniprot id: A0A075NS96
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

589873:EP13 RS13700
gene id: 589873:EP13_RS13700
uniprot id: A0A075P1I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

589873:EP13 RS07865
gene id: 589873:EP13_RS07865
uniprot id: A0A075NYJ2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

589873:EP13 RS10475
gene id: 589873:EP13_RS10475
uniprot id: A0A075P722
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

589873:EP13 RS01045
gene id: 589873:EP13_RS01045
uniprot id: A0A075P206
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS18020
gene id: 589873:EP13_RS18020
uniprot id: A0A075P6E2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

589873:EP13 RS11900
gene id: 589873:EP13_RS11900
uniprot id: A0A353JIY9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS00100
gene id: 589873:EP13_RS00100
uniprot id: A0A075NX19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

589873:EP13 RS07775
gene id: 589873:EP13_RS07775
uniprot id: A0A075NVE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS18300
gene id: 589873:EP13_RS18300
uniprot id: A0A350P0J7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS02500
gene id: 589873:EP13_RS02500
uniprot id: A0A075NYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

589873:EP13 RS09070
gene id: 589873:EP13_RS09070
uniprot id: A0A075NZA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

589873:EP13 RS02895
gene id: 589873:EP13_RS02895
uniprot id: A0A075P319
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

589873:EP13 RS13060
gene id: 589873:EP13_RS13060
uniprot id: A0A075NY31
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

589873:EP13 RS17680
gene id: 589873:EP13_RS17680
uniprot id: A0A075P0L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

589873:EP13 RS12575
gene id: 589873:EP13_RS12575
uniprot id: A0A075P850
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS00350
gene id: 589873:EP13_RS00350
uniprot id: A0A075NRW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

589873:EP13 RS00535
gene id: 589873:EP13_RS00535
uniprot id: A0A075NVD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

589873:EP13 RS10760
gene id: 589873:EP13_RS10760
uniprot id: A0A075P049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

589873:EP13 RS03130
gene id: 589873:EP13_RS03130
uniprot id: A0A075NWD4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

589873:EP13 RS18465
gene id: 589873:EP13_RS18465
uniprot id: A0A075P422
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS08435
gene id: 589873:EP13_RS08435
uniprot id: A0A075NYV6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

589873:EP13 RS09325
gene id: 589873:EP13_RS09325
uniprot id: A0A075NZE9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

589873:EP13 RS09670
gene id: 589873:EP13_RS09670
uniprot id: A0A075P6R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

589873:EP13 RS13225
gene id: 589873:EP13_RS13225
uniprot id: A0A075P3R3
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

589873:EP13 RS14555
gene id: 589873:EP13_RS14555
uniprot id: A0A075P2B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS17865
gene id: 589873:EP13_RS17865
uniprot id: A0A075PAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

589873:EP13 RS00275
gene id: 589873:EP13_RS00275
uniprot id: A0A075NRU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

589873:EP13 RS11615
gene id: 589873:EP13_RS11615
uniprot id: A0A075NXD0
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

589873:EP13 RS15720
gene id: 589873:EP13_RS15720
uniprot id: A0A075P546
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

589873:EP13 RS18960
gene id: 589873:EP13_RS18960
uniprot id: A0A353JLN4
names: Caution
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS00325
gene id: 589873:EP13_RS00325
uniprot id: A0A075NRV5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS04800
gene id: 589873:EP13_RS04800
uniprot id: A0A075NXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

589873:EP13 RS16495
gene id: 589873:EP13_RS16495
uniprot id: A0A075P5L0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

589873:EP13 RS17155
gene id: 589873:EP13_RS17155
uniprot id: A0A075P3U9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS02360
gene id: 589873:EP13_RS02360
uniprot id: A0A075NVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

589873:EP13 RS17040
gene id: 589873:EP13_RS17040
uniprot id: A0A075P3C8
names: Similarity
messages: Belongs to the GST superfamily.

589873:EP13 RS09410
gene id: 589873:EP13_RS09410
uniprot id: A0A075NWC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

589873:EP13 RS15370
gene id: 589873:EP13_RS15370
uniprot id: A0A075P9N6
names: Similarity
messages: Belongs to the peptidase M1 family.

589873:EP13 RS08820
gene id: 589873:EP13_RS08820
uniprot id: A0A075NZ24
names: Similarity
messages: Belongs to the ClpA/ClpB family.

589873:EP13 RS02975
gene id: 589873:EP13_RS02975
uniprot id: A0A075NW82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS15275
gene id: 589873:EP13_RS15275
uniprot id: A0A358E3C3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS05995
gene id: 589873:EP13_RS05995
uniprot id: A0A075P0D9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

589873:EP13 RS01140
gene id: 589873:EP13_RS01140
uniprot id: A0A075NV97
names: Similarity
messages: Belongs to the glycosyl hydrolase.

589873:EP13 RS10210
gene id: 589873:EP13_RS10210
uniprot id: A0A075NZS7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS05855
gene id: 589873:EP13_RS05855
uniprot id: A0A075NUK2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS04295
gene id: 589873:EP13_RS04295
uniprot id: A0A075NZF4
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS03645
gene id: 589873:EP13_RS03645
uniprot id: A0A075NWN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

589873:EP13 RS04705
gene id: 589873:EP13_RS04705
uniprot id: A0A075NX35
names: Similarity
messages: Belongs to the skp family.

589873:EP13 RS05190
gene id: 589873:EP13_RS05190
uniprot id: A0A075NXI4
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

589873:EP13 RS12375
gene id: 589873:EP13_RS12375
uniprot id: A0A353JJ13
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS06340
gene id: 589873:EP13_RS06340
uniprot id: A0A075NY61
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

589873:EP13 RS17270
gene id: 589873:EP13_RS17270
uniprot id: A0A075P3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS03480
gene id: 589873:EP13_RS03480
uniprot id: A0A075NWI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

589873:EP13 RS03385
gene id: 589873:EP13_RS03385
uniprot id: A0A075NTF8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

589873:EP13 RS08425
gene id: 589873:EP13_RS08425
uniprot id: A0A075NVS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

589873:EP13 RS07655
gene id: 589873:EP13_RS07655
uniprot id: A0A075NYF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

589873:EP13 RS13090
gene id: 589873:EP13_RS13090
uniprot id: A0A075P3N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS08280
gene id: 589873:EP13_RS08280
uniprot id: A0A075NYS1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS14175
gene id: 589873:EP13_RS14175
uniprot id: A0A075P4C8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

589873:EP13 RS14170
gene id: 589873:EP13_RS14170
uniprot id: A0A075NYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

589873:EP13 RS10360
gene id: 589873:EP13_RS10360
uniprot id: A0A075P271
names: Subcellular Location Annotation
messages: Cytoplasm

589873:EP13 RS03020
gene id: 589873:EP13_RS03020
uniprot id: A0A075NWA5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

589873:EP13 RS08265
gene id: 589873:EP13_RS08265
uniprot id: A0A075NYU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

589873:EP13 RS09590
gene id: 589873:EP13_RS09590
uniprot id: A0A075P6N6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

589873:EP13 RS02490
gene id: 589873:EP13_RS02490
uniprot id: A0A075NVZ6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

589873:EP13 RS01910
gene id: 589873:EP13_RS01910
uniprot id: A0A075P2H8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

589873:EP13 RS01780
gene id: 589873:EP13_RS01780
uniprot id: A0A075P2F7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

589873:EP13 RS00610
gene id: 589873:EP13_RS00610
uniprot id: A0A075P1S5
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

589873:EP13 RS02945
gene id: 589873:EP13_RS02945
uniprot id: A0A075P332
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS16480
gene id: 589873:EP13_RS16480
uniprot id: A0A075PA52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

589873:EP13 RS05500
gene id: 589873:EP13_RS05500
uniprot id: A0A075P036
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS16810
gene id: 589873:EP13_RS16810
uniprot id: A0A075P085
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

589873:EP13 RS14160
gene id: 589873:EP13_RS14160
uniprot id: A0A075P919
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

589873:EP13 RS11960
gene id: 589873:EP13_RS11960
uniprot id: A0A075NXJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

589873:EP13 RS08840
gene id: 589873:EP13_RS08840
uniprot id: A0A075P1L7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

589873:EP13 RS00810
gene id: 589873:EP13_RS00810
uniprot id: A0A075NV21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

589873:EP13 RS07545
gene id: 589873:EP13_RS07545
uniprot id: A0A075P135
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

589873:EP13 RS17615
gene id: 589873:EP13_RS17615
uniprot id: A0A075PAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS04115
gene id: 589873:EP13_RS04115
uniprot id: A0A075NTN1
names: Similarity
messages: Belongs to the MipA/OmpV family.

589873:EP13 RS09600
gene id: 589873:EP13_RS09600
uniprot id: A0A075NWE9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

589873:EP13 RS03935
gene id: 589873:EP13_RS03935
uniprot id: A0A353JG82
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS04545
gene id: 589873:EP13_RS04545
uniprot id: A0A075NZK3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

589873:EP13 RS04335
gene id: 589873:EP13_RS04335
uniprot id: A0A075NX25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

589873:EP13 RS03190
gene id: 589873:EP13_RS03190
uniprot id: A0A075NYZ4
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS09710
gene id: 589873:EP13_RS09710
uniprot id: A0A075P1X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

589873:EP13 RS04230
gene id: 589873:EP13_RS04230
uniprot id: A0A075NZE8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

589873:EP13 RS03975
gene id: 589873:EP13_RS03975
uniprot id: A0A075NWV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

589873:EP13 RS15925
gene id: 589873:EP13_RS15925
uniprot id: A0A075P325
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

589873:EP13 RS06145
gene id: 589873:EP13_RS06145
uniprot id: A0A075NY39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

589873:EP13 RS07065
gene id: 589873:EP13_RS07065
uniprot id: A0A075NY40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

589873:EP13 RS04830
gene id: 589873:EP13_RS04830
uniprot id: A0A075NTW9
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

589873:EP13 RS14105
gene id: 589873:EP13_RS14105
uniprot id: A0A075P1V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

589873:EP13 RS11390
gene id: 589873:EP13_RS11390
uniprot id: A0A075P2V3
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS12850
gene id: 589873:EP13_RS12850
uniprot id: A0A075P140
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

589873:EP13 RS09315
gene id: 589873:EP13_RS09315
uniprot id: A0A075NZB8
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

589873:EP13 RS02295
gene id: 589873:EP13_RS02295
uniprot id: A0A075NYF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

589873:EP13 RS18135
gene id: 589873:EP13_RS18135
uniprot id: A0A075P3V2
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS07060
gene id: 589873:EP13_RS07060
uniprot id: A0A075P0W2
names: Similarity
messages: Belongs to the YciI family.

589873:EP13 RS12610
gene id: 589873:EP13_RS12610
uniprot id: A0A075NXV5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

589873:EP13 RS14415
gene id: 589873:EP13_RS14415
uniprot id: A0A075P1Z9
names: Similarity
messages: Belongs to the threonine synthase family.

589873:EP13 RS18080
gene id: 589873:EP13_RS18080
uniprot id: A0A075P3U3
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

589873:EP13 RS04885
gene id: 589873:EP13_RS04885
uniprot id: A0A075NZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

589873:EP13 RS12460
gene id: 589873:EP13_RS12460
uniprot id: A0A075NXS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

589873:EP13 RS14285
gene id: 589873:EP13_RS14285
uniprot id: A0A075P4E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

589873:EP13 RS13420
gene id: 589873:EP13_RS13420
uniprot id: A0A075P3U7
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

589873:EP13 RS02205
gene id: 589873:EP13_RS02205
uniprot id: A0A075P2N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS14550
gene id: 589873:EP13_RS14550
uniprot id: A0A075P985
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS07520
gene id: 589873:EP13_RS07520
uniprot id: A0A075P132
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

589873:EP13 RS08140
gene id: 589873:EP13_RS08140
uniprot id: A0A075NVM7
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

589873:EP13 RS10385
gene id: 589873:EP13_RS10385
uniprot id: A0A075P275
names: Similarity
messages: Belongs to the ArsC family.

589873:EP13 RS18500
gene id: 589873:EP13_RS18500
uniprot id: A0A075P4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS14140
gene id: 589873:EP13_RS14140
uniprot id: A0A075P232
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

589873:EP13 RS15405
gene id: 589873:EP13_RS15405
uniprot id: A0A075P2S9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

589873:EP13 RS03615
gene id: 589873:EP13_RS03615
uniprot id: A0A075NWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

589873:EP13 RS04325
gene id: 589873:EP13_RS04325
uniprot id: A0A075NWZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

589873:EP13 RS02010
gene id: 589873:EP13_RS02010
uniprot id: A0A075P2J5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

589873:EP13 RS18210
gene id: 589873:EP13_RS18210
uniprot id: A0A075P3W8
names: Similarity
messages: Belongs to the GSP N family.

589873:EP13 RS03665
gene id: 589873:EP13_RS03665
uniprot id: A0A075NZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS07285
gene id: 589873:EP13_RS07285
uniprot id: A0A075NYF8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

589873:EP13 RS12275
gene id: 589873:EP13_RS12275
uniprot id: A0A075NXP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS01445
gene id: 589873:EP13_RS01445
uniprot id: A0A075NVM0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

589873:EP13 RS03430
gene id: 589873:EP13_RS03430
uniprot id: A0A075NWI2
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

589873:EP13 RS06930
gene id: 589873:EP13_RS06930
uniprot id: A0A075NY18
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS17845
gene id: 589873:EP13_RS17845
uniprot id: A0A075P6B6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

589873:EP13 RS03260
gene id: 589873:EP13_RS03260
uniprot id: A0A075NTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS15055
gene id: 589873:EP13_RS15055
uniprot id: A0A075P291
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

589873:EP13 RS00820
gene id: 589873:EP13_RS00820
uniprot id: A0A075NVF5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

589873:EP13 RS09160
gene id: 589873:EP13_RS09160
uniprot id: A0A075NZB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

589873:EP13 RS08790
gene id: 589873:EP13_RS08790
uniprot id: A0A075P1L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

589873:EP13 RS00670
gene id: 589873:EP13_RS00670
uniprot id: A0A075NS41
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

589873:EP13 RS14025
gene id: 589873:EP13_RS14025
uniprot id: A0A075P481
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

589873:EP13 RS00095
gene id: 589873:EP13_RS00095
uniprot id: A0A075NRQ9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

589873:EP13 RS18655
gene id: 589873:EP13_RS18655
uniprot id: A0A075P6R2
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

589873:EP13 RS07470
gene id: 589873:EP13_RS07470
uniprot id: A0A075P120
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

589873:EP13 RS09030
gene id: 589873:EP13_RS09030
uniprot id: A0A075P1N2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

589873:EP13 RS10280
gene id: 589873:EP13_RS10280
uniprot id: A0A075P257
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS09135
gene id: 589873:EP13_RS09135
uniprot id: A0A075NW83
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS10370
gene id: 589873:EP13_RS10370
uniprot id: A0A075P704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

589873:EP13 RS17310
gene id: 589873:EP13_RS17310
uniprot id: A0A075P3H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS07350
gene id: 589873:EP13_RS07350
uniprot id: A0A075NYA2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

589873:EP13 RS10255
gene id: 589873:EP13_RS10255
uniprot id: A0A075P253
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS16880
gene id: 589873:EP13_RS16880
uniprot id: A0A075P398
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS18395
gene id: 589873:EP13_RS18395
uniprot id: A0A075P4G9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

589873:EP13 RS11855
gene id: 589873:EP13_RS11855
uniprot id: A0A075NXH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

589873:EP13 RS12475
gene id: 589873:EP13_RS12475
uniprot id: A0A075P835
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

589873:EP13 RS08465
gene id: 589873:EP13_RS08465
uniprot id: A0A075P1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

589873:EP13 RS17455
gene id: 589873:EP13_RS17455
uniprot id: A0A075P3J8
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

589873:EP13 RS12750
gene id: 589873:EP13_RS12750
uniprot id: A0A075P118
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

589873:EP13 RS14905
gene id: 589873:EP13_RS14905
uniprot id: A0A075P4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS14040
gene id: 589873:EP13_RS14040
uniprot id: A0A075P1X3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

589873:EP13 RS00825
gene id: 589873:EP13_RS00825
uniprot id: A0A075NS70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

589873:EP13 RS04720
gene id: 589873:EP13_RS04720
uniprot id: A0A075NTV9
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

589873:EP13 RS03475
gene id: 589873:EP13_RS03475
uniprot id: A0A075P3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

589873:EP13 RS10645
gene id: 589873:EP13_RS10645
uniprot id: A0A075P001
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

589873:EP13 RS04940
gene id: 589873:EP13_RS04940
uniprot id: A0A075NX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

589873:EP13 RS06695
gene id: 589873:EP13_RS06695
uniprot id: A0A075P542
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

589873:EP13 RS02280
gene id: 589873:EP13_RS02280
uniprot id: A0A075P2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

589873:EP13 RS18315
gene id: 589873:EP13_RS18315
uniprot id: A0A075PB28
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

589873:EP13 RS04650
gene id: 589873:EP13_RS04650
uniprot id: A0A075NZM2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

589873:EP13 RS05120
gene id: 589873:EP13_RS05120
uniprot id: A0A075NU08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

589873:EP13 RS01110
gene id: 589873:EP13_RS01110
uniprot id: A0A075NXP7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

589873:EP13 RS02570
gene id: 589873:EP13_RS02570
uniprot id: A0A075P2V0
names: Similarity
messages: Belongs to the thioredoxin family.

589873:EP13 RS16840
gene id: 589873:EP13_RS16840
uniprot id: A0A075P5W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

589873:EP13 RS14400
gene id: 589873:EP13_RS14400
uniprot id: A0A075P283
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

589873:EP13 RS04765
gene id: 589873:EP13_RS04765
uniprot id: A0A075P464
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

589873:EP13 RS05380
gene id: 589873:EP13_RS05380
uniprot id: A0A075P4H9
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

589873:EP13 RS12255
gene id: 589873:EP13_RS12255
uniprot id: A0A075P377
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

589873:EP13 RS13600
gene id: 589873:EP13_RS13600
uniprot id: A0A075P8P2
names: Similarity
messages: Belongs to the DEAD box helicase family.

589873:EP13 RS01245
gene id: 589873:EP13_RS01245
uniprot id: A0A075NVB2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

589873:EP13 RS06485
gene id: 589873:EP13_RS06485
uniprot id: A0A075NXW5
names: Similarity
messages: Belongs to the SUI1 family.

589873:EP13 RS16595
gene id: 589873:EP13_RS16595
uniprot id: A0A075P028
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

589873:EP13 RS00960
gene id: 589873:EP13_RS00960
uniprot id: A0A075NXM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

589873:EP13 RS09970
gene id: 589873:EP13_RS09970
uniprot id: A0A075NWK8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

589873:EP13 RS01950
gene id: 589873:EP13_RS01950
uniprot id: A0A075NY76
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

589873:EP13 RS06435
gene id: 589873:EP13_RS06435
uniprot id: A0A075NXW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

589873:EP13 RS12320
gene id: 589873:EP13_RS12320
uniprot id: A0A075P0Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

589873:EP13 RS07210
gene id: 589873:EP13_RS07210
uniprot id: A0A075NYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

589873:EP13 RS08815
gene id: 589873:EP13_RS08815
uniprot id: A0A075P1L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

589873:EP13 RS05365
gene id: 589873:EP13_RS05365
uniprot id: A0A075NU62
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

589873:EP13 RS04710
gene id: 589873:EP13_RS04710
uniprot id: A0A075P450
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

589873:EP13 RS10950
gene id: 589873:EP13_RS10950
uniprot id: A0A075P7B7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

589873:EP13 RS00060
gene id: 589873:EP13_RS00060
uniprot id: A0A075NV67
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

589873:EP13 RS16015
gene id: 589873:EP13_RS16015
uniprot id: A0A075P2Q5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

589873:EP13 RS11170
gene id: 589873:EP13_RS11170
uniprot id: A0A075NX44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

589873:EP13 RS09320
gene id: 589873:EP13_RS09320
uniprot id: A0A075P6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS08305
gene id: 589873:EP13_RS08305
uniprot id: A0A075NYS6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

589873:EP13 RS12615
gene id: 589873:EP13_RS12615
uniprot id: A0A075P3E4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

589873:EP13 RS12830
gene id: 589873:EP13_RS12830
uniprot id: A0A075P8A6
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

589873:EP13 RS12235
gene id: 589873:EP13_RS12235
uniprot id: A0A075P0S8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

589873:EP13 RS13695
gene id: 589873:EP13_RS13695
uniprot id: A0A075P408
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

589873:EP13 RS16335
gene id: 589873:EP13_RS16335
uniprot id: A0A075P393
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

589873:EP13 RS01715
gene id: 589873:EP13_RS01715
uniprot id: A0A075NVJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS00720
gene id: 589873:EP13_RS00720
uniprot id: A0A075NS50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS13415
gene id: 589873:EP13_RS13415
uniprot id: A0A358E420
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS00885
gene id: 589873:EP13_RS00885
uniprot id: A0A075NV31
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

589873:EP13 RS16635
gene id: 589873:EP13_RS16635
uniprot id: A0A075PA82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

589873:EP13 RS04935
gene id: 589873:EP13_RS04935
uniprot id: A0A075NZS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

589873:EP13 RS03565
gene id: 589873:EP13_RS03565
uniprot id: A0A075P3I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

589873:EP13 RS05175
gene id: 589873:EP13_RS05175
uniprot id: A0A075NZX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

589873:EP13 RS15480
gene id: 589873:EP13_RS15480
uniprot id: A0A075P2G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS03950
gene id: 589873:EP13_RS03950
uniprot id: A0A358DVU2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS04105
gene id: 589873:EP13_RS04105
uniprot id: A0A075P3T6
names: Similarity
messages: Belongs to the GST superfamily.

589873:EP13 RS03455
gene id: 589873:EP13_RS03455
uniprot id: A0A075NWI3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS01970
gene id: 589873:EP13_RS01970
uniprot id: A0A075NSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

589873:EP13 RS05095
gene id: 589873:EP13_RS05095
uniprot id: A0A075NU03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

589873:EP13 RS07035
gene id: 589873:EP13_RS07035
uniprot id: A0A075P0V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

589873:EP13 RS07330
gene id: 589873:EP13_RS07330
uniprot id: A0A075P5G6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

589873:EP13 RS06395
gene id: 589873:EP13_RS06395
uniprot id: A0A349TW91
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS01535
gene id: 589873:EP13_RS01535
uniprot id: A0A075NVG5
names: Similarity
messages: Belongs to the HypD family.

589873:EP13 RS10920
gene id: 589873:EP13_RS10920
uniprot id: A0A075P035
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

589873:EP13 RS08875
gene id: 589873:EP13_RS08875
uniprot id: A0A075NZ35
names: Similarity
messages: Belongs to the asparaginase 1 family.

589873:EP13 RS18485
gene id: 589873:EP13_RS18485
uniprot id: A0A075P6P0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS11190
gene id: 589873:EP13_RS11190
uniprot id: A0A075P0B7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

589873:EP13 RS18515
gene id: 589873:EP13_RS18515
uniprot id: A0A075P122
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

589873:EP13 RS10185
gene id: 589873:EP13_RS10185
uniprot id: A0A075NZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

589873:EP13 RS07570
gene id: 589873:EP13_RS07570
uniprot id: A0A075P138
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS06265
gene id: 589873:EP13_RS06265
uniprot id: A0A075P0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS04490
gene id: 589873:EP13_RS04490
uniprot id: A0A075NTT1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

589873:EP13 RS00660
gene id: 589873:EP13_RS00660
uniprot id: A0A075P1T5
names: Similarity
messages: Belongs to the RutC family.

589873:EP13 RS13080
gene id: 589873:EP13_RS13080
uniprot id: A0A075P1F5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS18430
gene id: 589873:EP13_RS18430
uniprot id: A0A075P111
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

589873:EP13 RS18425
gene id: 589873:EP13_RS18425
uniprot id: A0A075P4H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

589873:EP13 RS01415
gene id: 589873:EP13_RS01415
uniprot id: A0A075NVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

589873:EP13 RS07970
gene id: 589873:EP13_RS07970
uniprot id: A0A075P182
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

589873:EP13 RS11635
gene id: 589873:EP13_RS11635
uniprot id: A0A075P7R0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

589873:EP13 RS15235
gene id: 589873:EP13_RS15235
uniprot id: A0A075P2C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

589873:EP13 RS00050
gene id: 589873:EP13_RS00050
uniprot id: A0A075NUK9
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

589873:EP13 RS05265
gene id: 589873:EP13_RS05265
uniprot id: A0A075P4G3
names: Similarity
messages: Belongs to the peptidase M13 family.

589873:EP13 RS09035
gene id: 589873:EP13_RS09035
uniprot id: A0A349TTP7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS06200
gene id: 589873:EP13_RS06200
uniprot id: A0A075P4V6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

589873:EP13 RS11570
gene id: 589873:EP13_RS11570
uniprot id: A0A075P0F6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

589873:EP13 RS11715
gene id: 589873:EP13_RS11715
uniprot id: A0A075P0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

589873:EP13 RS11350
gene id: 589873:EP13_RS11350
uniprot id: A0A075P7M4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

589873:EP13 RS10290
gene id: 589873:EP13_RS10290
uniprot id: A0A075P6Z5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

589873:EP13 RS12130
gene id: 589873:EP13_RS12130
uniprot id: A0A075P0Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

589873:EP13 RS06245
gene id: 589873:EP13_RS06245
uniprot id: A0A075NXT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

589873:EP13 RS15975
gene id: 589873:EP13_RS15975
uniprot id: A0A075P336
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

589873:EP13 RS06585
gene id: 589873:EP13_RS06585
uniprot id: A0A075NXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

589873:EP13 RS00125
gene id: 589873:EP13_RS00125
uniprot id: A0A075NX24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

589873:EP13 RS02345
gene id: 589873:EP13_RS02345
uniprot id: A0A075NVX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

589873:EP13 RS15590
gene id: 589873:EP13_RS15590
uniprot id: A0A075NZI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS05330
gene id: 589873:EP13_RS05330
uniprot id: A0A075P4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

589873:EP13 RS16275
gene id: 589873:EP13_RS16275
uniprot id: A0A075P2U4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

589873:EP13 RS16090
gene id: 589873:EP13_RS16090
uniprot id: A0A075P5E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

589873:EP13 RS07195
gene id: 589873:EP13_RS07195
uniprot id: A0A075P0X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

589873:EP13 RS09055
gene id: 589873:EP13_RS09055
uniprot id: A0A075P1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

589873:EP13 RS08540
gene id: 589873:EP13_RS08540
uniprot id: A0A075NYY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

589873:EP13 RS15620
gene id: 589873:EP13_RS15620
uniprot id: A0A075P525
names: Subcellular Location Annotation
messages: Membrane

589873:EP13 RS12535
gene id: 589873:EP13_RS12535
uniprot id: A0A075NXU4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

589873:EP13 RS07565
gene id: 589873:EP13_RS07565
uniprot id: A0A075NVA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

589873:EP13 RS05520
gene id: 589873:EP13_RS05520
uniprot id: A0A075NU96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

589873:EP13 RS16340
gene id: 589873:EP13_RS16340
uniprot id: A0A075NZY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

589873:EP13 RS12215
gene id: 589873:EP13_RS12215
uniprot id: A0A075P7Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

589873:EP13 RS08450
gene id: 589873:EP13_RS08450
uniprot id: A0A075P625
names: Subcellular Location Annotation
messages: Cell inner membrane

589873:EP13 RS04005
gene id: 589873:EP13_RS04005
uniprot id: A0A075NTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS00900
gene id: 589873:EP13_RS00900
uniprot id: A0A075NS83
names: Similarity
messages: Belongs to the histone deacetylase family.

589873:EP13 RS12785
gene id: 589873:EP13_RS12785
uniprot id: A0A075P186
names: Similarity
messages: Belongs to the PspA/IM30 family.

589873:EP13 RS04340
gene id: 589873:EP13_RS04340
uniprot id: A0A075NTR5
names: Function
names: Miscellaneous
names: Similarity
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.

589873:EP13 RS14300
gene id: 589873:EP13_RS14300
uniprot id: A0A075P262
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

589873:EP13 RS07360
gene id: 589873:EP13_RS07360
uniprot id: A0A075NYH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

589873:EP13 RS15930
gene id: 589873:EP13_RS15930
uniprot id: A0A075NZQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

589873:EP13 RS17520
gene id: 589873:EP13_RS17520
uniprot id: A0A075P659
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

589873:EP13 RS18795
gene id: 589873:EP13_RS18795
uniprot id: A0A075P4P8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

589873:EP13 RS18535
gene id: 589873:EP13_RS18535
uniprot id: A0A075P4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

589873:EP13 RS16770
gene id: 589873:EP13_RS16770
uniprot id: A0A350P9V8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

589873:EP13 RS03755
gene id: 589873:EP13_RS03755
uniprot id: A0A075NWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

589873:EP13 RS08380
gene id: 589873:EP13_RS08380
uniprot id: A0A075P1E4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

589873:EP13 RS09490
gene id: 589873:EP13_RS09490
uniprot id: A0A075NWD3
names: Similarity
messages: Belongs to the HIBADH-related family.

589873:EP13 RS10105
gene id: 589873:EP13_RS10105
uniprot id: A0A075NZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

589873:EP13 RS01190
gene id: 589873:EP13_RS01190
uniprot id: A0A075NXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

589873:EP13 RS13450
gene id: 589873:EP13_RS13450
uniprot id: A0A075P3V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

589873:EP13 RS09835
gene id: 589873:EP13_RS09835
uniprot id: A0A075NWJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

589873:EP13 RS08975
gene id: 589873:EP13_RS08975
uniprot id: A0A075NZ55
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.